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Research Topics
Genomes and Genes
Gene Symbol: dld
Description: deltaD
Alias: sc:d0402, delta-like protein D, aei, after eight protein
Species: zebrafish
Products: dld
Top Publications
Scientific Experts
More Information
- van Eeden F, Granato M, Schach U, Brand M, Furutani Seiki M, Haffter P, et al. Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development. 1996;123:153-64 pubmed..in fused somites (fss) and beamter (bea) affect all somites, whereas mutations in deadly seven (des), after eight (aei) and white tail (wit) only affect the more posterior somites...
- Itoh M, Kim C, Palardy G, Oda T, Jiang Y, Maust D, et al. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev Cell. 2003;4:67-82 pubmed..This facilitates intramembranous cleavage of the remaining Notch receptor, release of the Notch intracellular fragment, and activation of target genes in neighboring cells. ..
- Hans S, Campos Ortega J. On the organisation of the regulatory region of the zebrafish deltaD gene. Development. 2002;129:4773-84 pubmed..Transcriptional control of deltaD by proneural proteins therefore represents a molecular target for the regulatory feedback loop mediated by the Notch pathway in lateral inhibition. ..
- Oates A, Mueller C, Ho R. Cooperative function of deltaC and her7 in anterior segment formation. Dev Biol. 2005;280:133-49 pubmed..Thus, anterior segmentation requires the functions of both her and delta family members in a parallel manner, suggesting that the segmentation oscillator operates in paraxial mesoderm along the entire vertebrate axis. ..
- Giudicelli F, Ozbudak E, Wright G, Lewis J. Setting the tempo in development: an investigation of the zebrafish somite clock mechanism. PLoS Biol. 2007;5:e150 pubmed
- Smithers L, Haddon C, Jiang Y, Lewis J. Sequence and embryonic expression of deltaC in the zebrafish. Mech Dev. 2000;90:119-23 pubmed..There is expression also in notochord, blood vessels and pronephros. ..
- Barrios A, Poole R, Durbin L, Brennan C, Holder N, Wilson S. Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis. Curr Biol. 2003;13:1571-82 pubmed..We propose a new role for Eph receptors and Ephrins as intercellular signaling molecules that establish cell polarity during mesenchymal-to-epithelial transition of the paraxial mesoderm. ..
- Sieger D, Tautz D, Gajewski M. The role of Suppressor of Hairless in Notch mediated signalling during zebrafish somitogenesis. Mech Dev. 2003;120:1083-94 pubmed..This phenotype is stronger than the known amorphic phenotypes for notch1 (des) or deltaD (aei) in zebrafish, but mimicks the knockout phenotype of RBP-Jkappa gene in the mouse, which is the homologue of Su(H)...
- Crosnier C, Vargesson N, Gschmeissner S, Ariza McNaughton L, Morrison A, Lewis J. Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine. Development. 2005;132:1093-104 pubmed..In particular, the Notch ligand DeltaD (Delta1 in the mouse) is expressed in cells of the secretory lineage. In an aei mutant, where DeltaD is defective, secretory cells are overproduced...
- van Eeden F, Holley S, Haffter P, Nusslein Volhard C. Zebrafish segmentation and pair-rule patterning. Dev Genet. 1998;23:65-76 pubmed..However, both the relationship between these two groups of genes within the genetic heirarchy governing segmentation and the precise roles that they play during segmentation likely differ significantly between the two organisms. ..
- Mahler J, Filippi A, Driever W. DeltaA/DeltaD regulate multiple and temporally distinct phases of notch signaling during dopaminergic neurogenesis in zebrafish. J Neurosci. 2010;30:16621-35 pubmed publisher..precursor pools, as olig2 expression in ventral diencephalic dopaminergic precursors is affected in dla/dld mutants. DeltaA/D act upstream of sim1a and otpa during dopaminergic specification...
- Park H, Appel B. Delta-Notch signaling regulates oligodendrocyte specification. Development. 2003;130:3747-55 pubmed..Our data provide evidence that Notch signaling maintains subsets of ventral spinal cord precursors during neuronal birth and, acting with other temporally and spatially restricted factors, specifies them for oligodendrocyte fate. ..
- Kawamura A, Koshida S, Hijikata H, Ohbayashi A, Kondoh H, Takada S. Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites. Dev Cell. 2005;9:735-44 pubmed..Thus, ripply1 plays dual roles in the transition from the PSM to somites: termination of the segmentation program in the PSM and maintenance of the rostrocaudal polarity. ..
- Diks S, Sartori da Silva M, Hillebrands J, Bink R, Versteeg H, van Rooijen C, et al. d-Asb11 is an essential mediator of canonical Delta-Notch signalling. Nat Cell Biol. 2008;10:1190-8 pubmed publisher..We conclude that d-Asb11 is a component in the regulation of Delta-Notch signalling, important in fine-tuning the lateral inhibition gradients between DeltaA and Notch through a cell non-autonomous mechanism. ..
- Bingham S, Chaudhari S, Vanderlaan G, Itoh M, Chitnis A, Chandrasekhar A. Neurogenic phenotype of mind bomb mutants leads to severe patterning defects in the zebrafish hindbrain. Dev Dyn. 2003;228:451-63 pubmed
- Mara A, Schroeder J, Chalouni C, Holley S. Priming, initiation and synchronization of the segmentation clock by deltaD and deltaC. Nat Cell Biol. 2007;9:523-30 pubmed..Oscillations of adjacent cells are synchronized and amplified by deltaC in the posterior presomitic mesoderm as cell movement subsides and cells maintain stable neighbour relationships. ..
- Takke C, Dornseifer P, v Weizsäcker E, Campos Ortega J. her4, a zebrafish homologue of the Drosophila neurogenic gene E(spl), is a target of NOTCH signalling. Development. 1999;126:1811-21 pubmed..These results suggest that her4 acts as a target of notch-mediated signals that regulate primary neurogenesis. ..
- Cheng Y, Amoyel M, Qiu X, Jiang Y, Xu Q, Wilkinson D. Notch activation regulates the segregation and differentiation of rhombomere boundary cells in the zebrafish hindbrain. Dev Cell. 2004;6:539-50 pubmed..These findings reveal that Notch activation couples the regulation of location and differentiation in hindbrain boundary cells. Such coupling may be important for these cells to act as a stable signaling center. ..
- Jahangiri L, Nelson A, Wardle F. A cis-regulatory module upstream of deltaC regulated by Ntla and Tbx16 drives expression in the tailbud, presomitic mesoderm and somites. Dev Biol. 2012;371:110-20 pubmed publisher..This CRM is bound by both Ntla and Tbx16 at a cluster of T-box binding sites, which are required in combination for activation of the CRM. ..
- Okigawa S, Mizoguchi T, Okano M, Tanaka H, Isoda M, Jiang Y, et al. Different combinations of Notch ligands and receptors regulate V2 interneuron progenitor proliferation and V2a/V2b cell fate determination. Dev Biol. 2014;391:196-206 pubmed publisher..In conclusion, V2-IN cell progenitor proliferation and V2a/V2b cell fate determination involve signaling through different sets of Notch ligand-receptor combinations that occur concurrently during development in zebrafish. ..
- Palardy G, Chitnis A. Identification of the Mind Bomb1 Interaction Domain in Zebrafish DeltaD. PLoS ONE. 2015;10:e0127864 pubmed publisher..As a result, ectopic expression of DeltaD lacking an effective MID results in a failure of Notch-mediated lateral inhibition and a neurogenic phenotype. ..
- Dill K, Amacher S. tortuga refines Notch pathway gene expression in the zebrafish presomitic mesoderm at the post-transcriptional level. Dev Biol. 2005;287:225-36 pubmed
- Snow C, Peterson M, Khalil A, Henry C. Muscle development is disrupted in zebrafish embryos deficient for fibronectin. Dev Dyn. 2008;237:2542-53 pubmed publisher..morphogenesis is more disrupted in fn morphants than in a mutant where initial somite boundaries did not form, aei/deltaD...
- Bink R, Habuchi H, Lele Z, Dolk E, Joore J, Rauch G, et al. Heparan sulfate 6-o-sulfotransferase is essential for muscle development in zebrafish. J Biol Chem. 2003;278:31118-27 pubmed..In conclusion, our results show that transfer of sulfate to specific positions on glycosaminoglycans is essential for muscle development. ..
- Dias T, Yang Y, Ogai K, Becker T, Becker C. Notch signaling controls generation of motor neurons in the lesioned spinal cord of adult zebrafish. J Neurosci. 2012;32:3245-52 pubmed publisher..This demonstrates that Notch is a negative signal for regenerative neurogenesis, and, importantly, that spinal motor neuron regeneration can be augmented in an adult vertebrate by inhibiting Notch signaling. ..
- Madelaine R, Blader P. A cluster of non-redundant Ngn1 binding sites is required for regulation of deltaA expression in zebrafish. Dev Biol. 2011;350:198-207 pubmed publisher..These results suggest that evolutionary constraints on the mechanism by which Ngn1 regulates gene expression appear less strict than for Ascl1. ..
- Matsuda M, Chitnis A. Atoh1a expression must be restricted by Notch signaling for effective morphogenesis of the posterior lateral line primordium in zebrafish. Development. 2010;137:3477-87 pubmed publisher..Together, our observations reveal a genetic regulatory network that explains why atoh1a expression must be restricted by Notch signaling for effective morphogenesis of the pLLp. ..
- Roach G, Heath Wallace R, Cameron A, Emrah Ozel R, Hongay C, Baral R, et al. Loss of ascl1a prevents secretory cell differentiation within the zebrafish intestinal epithelium resulting in a loss of distal intestinal motility. Dev Biol. 2013;376:171-86 pubmed publisher..Loss of enteroendocrine cells reveals the critical need for enteroendocrine products in maintenance of normal intestinal motility. ..
- Lin C, He J, Zeng C, Loo M, Chang W, Zhang P, et al. microRNA-206 modulates an Rtn4a/Cxcr4a/Thbs3a axis in newly forming somites to maintain and stabilize the somite boundary formation of zebrafish embryos. Open Biol. 2017;7: pubmed publisher..Collectively, we suggest that miR-206 mediates a novel pathway, the Rtn4a/Cxcr4a/Thbs3a axis, that allows boundary cells to undergo MET and form somite boundaries in the newly forming somites of zebrafish embryos. ..
- He Y, Tang D, Li W, Chai R, Li H. Histone deacetylase 1 is required for the development of the zebrafish inner ear. Sci Rep. 2016;6:16535 pubmed publisher..Taken together, our results indicate that HDAC1 plays an important role in otic vesicle formation. ..
- Schebesta M, Serluca F. olig1 Expression identifies developing oligodendrocytes in zebrafish and requires hedgehog and notch signaling. Dev Dyn. 2009;238:887-98 pubmed publisher..Lastly, knockdown of Olig1 in an Olig2-sensitized background did result in defects in CNS myelination, indicating a functional overlap between Olig1 and Olig2 proteins. ..
- Therapontos C, Vargesson N. Zebrafish notch signalling pathway mutants exhibit trunk vessel patterning anomalies that are secondary to somite misregulation. Dev Dyn. 2010;239:2761-8 pubmed publisherThe Notch signalling pathway mutants, after-eight (aei), beamter (bea), and deadly-seven (des) have previously been used to study somitogenesis and neurogenesis. Notch signalling has also been shown to have roles in vascular development...
- Wan J, Ramachandran R, Goldman D. HB-EGF is necessary and sufficient for Müller glia dedifferentiation and retina regeneration. Dev Cell. 2012;22:334-47 pubmed publisher..These data provide a link between extracellular signaling and regeneration-associated gene expression in the injured retina and suggest strategies for stimulating retina regeneration in mammals. ..
- Stickney H, Barresi M, Devoto S. Somite development in zebrafish. Dev Dyn. 2000;219:287-303 pubmed..We show directly, for the first time, that muscle cell and sclerotome migrations occur at the same time. We end with a look at the many questions about somitogenesis that are still unanswered. ..
- Alunni A, Krecsmarik M, Bosco A, Galant S, Pan L, Moens C, et al. Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium. Development. 2013;140:3335-47 pubmed publisher..They implicate Notch3 at the top of this hierarchy to gate NSC activation and amplification, protecting the homeostasis of adult NSC reservoirs under physiological conditions. ..
- Zaucker A, Mercurio S, Sternheim N, Talbot W, Marlow F. notch3 is essential for oligodendrocyte development and vascular integrity in zebrafish. Dis Model Mech. 2013;6:1246-59 pubmed publisher..Our analysis of zebrafish notch3 mutants indicates that Notch3 regulates OPC development and mbp gene expression in larvae, and maintains vascular integrity in adults...
- Sampaio P, Ferreira R, Guerrero A, Pintado P, Tavares B, Amaro J, et al. Left-right organizer flow dynamics: how much cilia activity reliably yields laterality?. Dev Cell. 2014;29:716-28 pubmed publisher..We conclude that cilia number, dorsal anterior motile cilia clustering, and left flow are critical to situs solitus via robust asymmetric charon expression. ..
- Rothschild S, Lahvic J, Francescatto L, McLeod J, Burgess S, Tombes R. CaMK-II activation is essential for zebrafish inner ear development and acts through Delta-Notch signaling. Dev Biol. 2013;381:179-88 pubmed publisher..Continued expression and activation of CaMK-II in maculae and cristae in older embryos suggests continued roles in auditory sensory maturation and transduction. ..
- Fujita M, Cha Y, Pham V, Sakurai A, Roman B, Gutkind J, et al. Assembly and patterning of the vascular network of the vertebrate hindbrain. Development. 2011;138:1705-15 pubmed publisher..Knockdown of either cxcl12b or cxcr4a results in defects in basilar artery formation, showing that the assembly and patterning of this crucial artery depends on chemokine signaling. ..
- Appel B, Marasco P, McClung L, Latimer A. lunatic fringe regulates Delta-Notch induction of hypochord in zebrafish. Dev Dyn. 2003;228:281-6 pubmed
- Kok F, Oster E, Mentzer L, Hsieh J, Henry C, Sirotkin H. The role of the SPT6 chromatin remodeling factor in zebrafish embryogenesis. Dev Biol. 2007;307:214-26 pubmed..However, additional Spt6 mutant phenotypes are likely caused by vital functions of Spt6 in other pathways. ..
- Kroehne V, Freudenreich D, Hans S, Kaslin J, Brand M. Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors. Development. 2011;138:4831-41 pubmed publisher..Thus, regeneration after traumatic lesion of the adult zebrafish brain occurs efficiently from radial glia-type stem/progenitor cells. ..
- Chandrasekhar A, Schauerte H, Haffter P, Kuwada J. The zebrafish detour gene is essential for cranial but not spinal motor neuron induction. Development. 1999;126:2727-37 pubmed
- Lee H, Tseng W, Lo F, Liu T, Tsai H. FoxD5 mediates anterior-posterior polarity through upstream modulator Fgf signaling during zebrafish somitogenesis. Dev Biol. 2009;336:232-45 pubmed publisher..An Fgf-FoxD5-Mesps signaling network is therefore proposed. ..
- Münch J, González Rajal A, de la Pompa J. Notch regulates blastema proliferation and prevents differentiation during adult zebrafish fin regeneration. Development. 2013;140:1402-11 pubmed publisher..We conclude that Notch signalling maintains blastema cells in a plastic, undifferentiated and proliferative state, an essential requirement for fin regeneration. ..
- Niikura Y, Tabata Y, Tajima A, Inoue I, Arai K, Watanabe S. Zebrafish Numb homologue: phylogenetic evolution and involvement in regulation of left-right asymmetry. Mech Dev. 2006;123:407-14 pubmed
- Kikuchi Y, Verkade H, Reiter J, Kim C, Chitnis A, Kuroiwa A, et al. Notch signaling can regulate endoderm formation in zebrafish. Dev Dyn. 2004;229:756-62 pubmed..Altogether, these results suggest that Notch signaling plays a role in the formation of the endoderm, possibly in its segregation from the mesoderm. ..
- Geudens I, Herpers R, Hermans K, Segura I, Ruiz de Almodovar C, Bussmann J, et al. Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish. Arterioscler Thromb Vasc Biol. 2010;30:1695-702 pubmed publisher..At a later phase, Notch silencing impaired navigation of lymphatic intersomitic vessels along their arterial templates. These studies imply critical roles for Notch signaling in the formation and wiring of the lymphatic network. ..
- Takano A, Zochi R, Hibi M, Terashima T, Katsuyama Y. Function of strawberry notch family genes in the zebrafish brain development. Kobe J Med Sci. 2011;56:E220-30 pubmed..Knockdown of sbno1 specifically affects regionalization along the anterior-posterior axis of the brain. These results suggest essential roles of sbno genes in vertebrate brain development. ..
- He Y, Wang Z, Sun S, Tang D, Li W, Chai R, et al. HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish. Mol Neurobiol. 2016;53:5103-17 pubmed publisher..Our results indicate that HDAC3 plays a crucial role in regulating posterior lateral line (PLL) formation and provide evidence for epigenetic regulation in auditory organ development. ..
- Lopes S, Lourenço R, Pacheco L, Moreno N, Kreiling J, Saude L. Notch signalling regulates left-right asymmetry through ciliary length control. Development. 2010;137:3625-32 pubmed publisher..Notch signalling brings together ciliary length control and fluid flow hydrodynamics with transcriptional activation of laterality genes. In addition, our deltaD mutant analysis discloses an uncoupling between gut and heart laterality. ..
- Sidik H, Talbot W. A zinc finger protein that regulates oligodendrocyte specification, migration and myelination in zebrafish. Development. 2015;142:4119-28 pubmed publisher..Our results defined the function of a new zinc finger protein with specific function in oligodendrocyte specification, migration and myelination in the developing CNS. ..
- Lecaudey V, Ulloa E, Anselme I, Stedman A, Schneider Maunoury S, Pujades C. Role of the hindbrain in patterning the otic vesicle: a study of the zebrafish vhnf1 mutant. Dev Biol. 2007;303:134-43 pubmed..They suggest that, despite the evolution of inner ear structure and function, some of the mechanisms underlying the regionalisation of the otic vesicle in fish and amniotes have been conserved. ..
- Dong Z, Yang N, Yeo S, Chitnis A, Guo S. Intralineage directional Notch signaling regulates self-renewal and differentiation of asymmetrically dividing radial glia. Neuron. 2012;74:65-78 pubmed publisher..These findings reveal with single-cell resolution how self-renewal and differentiation become precisely segregated within asymmetrically dividing neural progenitor/stem lineages. ..
- Soni K, Choudhary A, Patowary A, Singh A, Bhatia S, Sivasubbu S, et al. miR-34 is maternally inherited in Drosophila melanogaster and Danio rerio. Nucleic Acids Res. 2013;41:4470-80 pubmed publisher..Here, we report for the first time, the maternal inheritance of an miRNA involved in development of the neuronal system in a vertebrate model system. ..
- Tucker B, Hepperle C, Kortschak D, Rainbird B, Wells S, Oates A, et al. Zebrafish Angiotensin II Receptor-like 1a (agtrl1a) is expressed in migrating hypoblast, vasculature, and in multiple embryonic epithelia. Gene Expr Patterns. 2007;7:258-65 pubmed..During segmentation stages, expression is observed in epithelial structures such as adaxial cells, border cells of the newly formed somites, developing lens, otic vesicles and venous vasculature. ..
- Romero Carvajal A, Navajas Acedo J, Jiang L, Kozlovskaja Gumbrienė A, Alexander R, Li H, et al. Regeneration of Sensory Hair Cells Requires Localized Interactions between the Notch and Wnt Pathways. Dev Cell. 2015;34:267-82 pubmed publisher..The striking similarities to other vertebrate stem cell compartments uniquely place zebrafish to help elucidate why mammals possess such low capacity to regenerate hair cells. ..
- Oates A, Rohde L, Ho R. Generation of segment polarity in the paraxial mesoderm of the zebrafish through a T-box-dependent inductive event. Dev Biol. 2005;283:204-14 pubmed
- Lissemore J, Starmer W. Phylogenetic analysis of vertebrate and invertebrate Delta/Serrate/LAG-2 (DSL) proteins. Mol Phylogenet Evol. 1999;11:308-19 pubmed..Finally, the linear order of EGF repeats has been conserved in the vertebrate Jagged/Serrate orthologs and vertebrate Delta orthologs. ..
- Chen W, Casey Corliss D. Three modules of zebrafish Mind bomb work cooperatively to promote Delta ubiquitination and endocytosis. Dev Biol. 2004;267:361-73 pubmed..Thus, the three functionally distinct modules of Mind bomb work cooperatively to regulate Notch signaling by associating with, ubiquitinating, and internalizing Delta. ..
- Taylor S, Alvarez Delfin K, Saade C, Thomas J, Thummel R, Fadool J, et al. The bHLH Transcription Factor NeuroD Governs Photoreceptor Genesis and Regeneration Through Delta-Notch Signaling. Invest Ophthalmol Vis Sci. 2015;56:7496-515 pubmed publisher..In contrast, during embryonic development, NeuroD governs photoreceptor maturation via mechanisms that are independent of Notch signaling. ..
- Chen Y, Lu Y, Ko T, Tsai M, Lin C, Lin C, et al. Zebrafish cdx1b regulates differentiation of various intestinal cell lineages. Dev Dyn. 2009;238:1021-32 pubmed publisher..Overall, our results suggest that zebrafish cdx1b plays important roles in regulating intestinal cell proliferation and the differentiation of various intestinal cell lineages. ..
- Banote R, Edling M, Eliassen F, Kettunen P, Zetterberg H, Abramsson A. ?-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner. Dev Biol. 2016;413:26-38 pubmed publisher..Our results suggest that Appb-regulated neurogenesis is mediated through balancing the Notch1a signaling pathway and provide new insights into the development of the Mauthner cell. ..
- Hsieh F, Ma T, Shih H, Lin S, Huang C, Wang H, et al. Dner inhibits neural progenitor proliferation and induces neuronal and glial differentiation in zebrafish. Dev Biol. 2013;375:1-12 pubmed publisher..This is the first study to demonstrate a role for Dner in neural progenitors and neuronal differentiation and provides new insights into mediation of neuronal development and differentiation by the Notch signaling pathway. ..
- Herrgen L, Ares S, Morelli L, Schroter C, Jülicher F, Oates A. Intercellular coupling regulates the period of the segmentation clock. Curr Biol. 2010;20:1244-53 pubmed publisher..Here we ask whether Delta-Notch coupling additionally influences the collective period of the segmentation clock...
- Kim A, Melick C, Clements W, Stachura D, Distel M, Panáková D, et al. Discrete Notch signaling requirements in the specification of hematopoietic stem cells. EMBO J. 2014;33:2363-73 pubmed publisher..downstream of Wnt16, which is required for HSC specification through its regulation of two Notch ligands, dlc and dld. Collectively, these findings demonstrate for the first time that multiple Notch signaling inputs are required to ..
- Gui J, Greene C, Sullivan C, Taylor W, Moore J, KIM C. Testing multiple hypotheses through IMP weighted FDR based on a genetic functional network with application to a new zebrafish transcriptome study. BioData Min. 2015;8:17 pubmed publisher..We compared the mRNA expression for each group and found over 200 differentially expressed genes and several enriched pathways including defense response pathways, arsenic response pathways, and the Notch signaling pathway. ..
- Hwang J, Kim H, Seok J, Kim J, Koun S, Park S, et al. Transcriptome analysis of the zebrafish mind bomb mutant. Mol Genet Genomics. 2009;281:77-85 pubmed publisher..Interestingly, it was suggested that the mib ( ta52b ) mutation may affect not only neurogenesis but also mesoderm development. These results provide new insights into Notch signaling pathway. ..
- Jülich D, Geisler R, Holley S. Integrinalpha5 and delta/notch signaling have complementary spatiotemporal requirements during zebrafish somitogenesis. Dev Cell. 2005;8:575-86 pubmed..Our data suggest that notch- and integrinalpha5-dependent cell polarization and Fibronectin matrix assembly occur concomitantly and interdependently during border morphogenesis. ..


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Queen Guinevere is torn between her love for Lancelot - the brilliant warrior she meets as a young woman - and her King Arthur Pendragon, the valiant knight who saves Camelot in its darkest hour.WATCH
Aspiring songstress Holly Moon admires the famous diva "Samantha" and attempts to sneak her own act on stage, in the same elite futuristic techno club. With a weird stroke of luck, Holly succeeds, but is unaware that "Samantha" really appears only with the help of an illegal, secret military computer program. The program uses the imagination of a real person to create a total virtual reality environment. At the club, the MC introduces Holly with ...WATCH
84 years later, a 101-year-old woman named Rose DeWitt Bukater tells the story to her granddaughter Lizzy Calvert, Brock Lovett, Lewis Bodine, Bobby Buell and Anatoly Mikailavich on the Keldysh about her life set in April 10th 1912, on a ship called Titanic when young Rose boards the departing ship with the upper-class passengers and her mother, Ruth DeWitt Bukater, and her fiancé, Caledon Hockley. Meanwhile, a drifter and artist named Jack Dawson and his ...WATCH

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Kapenguria MP Samuel Moroto this morning recorded a statement over inflammatory remarks he allegedly issued in connection with government's inaction following the loss of lives following devastating landslides.
Moroto confirmed he was summoned to the Kapenguria DCI offices where he recorded a statement on his public utterances during the mass burial of the landslides.
Speaking after recording the statement, Moroto who was accompanied by Sigor MP Peter Lochakapong said his remarks were made in mourning.
"This morning, I was summoned by DCI officers to Kapenguria Police Station where I have recorded a statement over alleged incitement during the mass burial of the victims,"said Moroto.
Moroto had in his remarks accused the National Government of neglecting West Pokot residents. He hit out President Uhuru Kenyatta for inaction on the tragedy.
Moroto lauded investigative agencies in the county for the way they handed the matter but pointed out that he doesn't regret his remarks since he was defending his people.
"We were mourning and those were emotional remarks but it was true because upto now we have not recovered some bodies buried in the debris," added Moroto.
He said he was happy that President Uhuru Kenyatta had in his recent address to the Nation announced that he has mobilised funds and made available 5.2 billion shillings to provide relief food supplies, undertake a resettlement programme for communities displaced by floods.
He said the funds will also support reconstruction of homes that have been destroyed, address health concerns and reconstruct critical infrastructure, including water supplies.
"I am closely monitoring the implementation of this disaster recovery operation to ensure that the affected households are able to regain some stability as soon as possible," said Uhuru.
The Head of State added,"If you have any concerns about the implementation of the programme, I encourage you to share it with your county administration."


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In a Blow to Maduro, Russia Withdraws Key Defense Support to Venezuela
Russia has been one of Maduro's major supporters in its standoff with the U.S.
MOSCOW—Russia has withdrawn key defense advisers from Venezuela, an embarrassment for President Nicolás Maduro as Moscow weighs the leader's political and economic resilience against growing U.S. pressure.
Russian state defense contractor Rostec, which has trained Venezuelan troops and advised on securing arms contracts, has cut its staff in Venezuela to just a few dozen from about 1,000 at the height of cooperation between Moscow and Caracas several years ago, said a person close to the Russian defense ministry.
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- How to Get Back Together With Your Ex
How To Get Your Ex Girlfriend Back
Updated: May 5, References. Relationships often end in a whirlwind of doubt and bitter accusation. You probably said a few things you didn't mean, and she fought back. Now that you've had a little bit of time to think about what's been lost, you know you want her back. If you put your heart and mind to it, you might be able to win her over all over again.
Fixing whatever went wrong in the first place can be all it takes to prove that you've changed. If you want to get your ex girlfriend back after a break-up, first take some time to get your own life back on track and recover emotionally. This might mean getting some new clothes, going to the gym, spending more time with your friends, or getting invested in a new hobby.
This will show her that you can be independent and that you respect yourself, which will make her respect you more. Girls typically want to be with guys who have a good attitude about life, so try to act positive and avoid being outwardly jealous or mopey. You should also give her space for a little while so she has time to reflect on the good parts of the relationship and potentially miss you.
For more tips on winning over your ex girlfriend again, like how to tell her you still have feelings for her, keep reading! Did this summary help you? Yes No. Random Article. Home Random Terms of Use. We use cookies to make wikiHow great. By using our site, you agree to our cookie policy.
This article was co-authored by our trained team of editors and researchers who validated it for accuracy and comprehensiveness. Together, they cited information from 6 references. Set The Stage.
Make The Move. Tips and Warnings. Related Articles. Article Summary. Method 1 of Get your life back on track. So you've been in a relationship for some time, and maybe your girlfriend has just broken it off. It's a sad and lonely time for you right now, but focus on the things you can change about yourself before you move back on to her. Girls want to see self-improvement from guys. Maybe your girlfriend complained about something you did while you two were in your relationship.
Maybe there's something that you know you can improve simply because it will make you a better person. Well, now's the time to strike. Cut your video game playing down to a reasonable time, if that's what she wants, or start wearing cleaner clothes when you're around her.
If you focus on being a better person while apart, you can go back to her with the "evidence" that you're a new guy. Recover emotionally. You don't stand a chance of getting your ex back if you're not emotionally calm and controlled. Like it or not, showing her that you can deal with life on your own will attract her back to you.
That's because girls like men who are self-sufficient and independent. So go out to the gym, visit the movies with friends, or start an adventure. If you're having a great time, she'll want to be there with you. Get some new clothes. New times call for new duds.
It's a subtle change in you, but the importance will be clear to her: your new outer shell will signal deeper changes underneath. Get that new shirt that you've been wanting to buy, or those new pair of jeans. Looking sharp is an important aspect of physical attraction, and if she sees you looking great in unfamiliar clothes, she'll sense that there's been forward movement, if not wholesale change.
Get the right attitude. Getting your ex-girlfriend back starts with finding the right attitude. Girls, for the most part, want to see mature [2] X Research source , independent guys who like to have fun and know what they're good at.
We know that's a lot to work, so start small if you're feeling overwhelmed. Stop being jealous. Being jealous will get you nowhere. Plus, what you're non-verbally telling her is that you want to control her. No one wants to be controlled. So learn to fight your jealousy if you can, and focus on being non-threatening. You'll get more bees with honey than you will with vinegar.
Act like nothing is wrong. Even if your guts are tumbling like clothes in a washing machine, try not to let her know. She's probably not going to want you back if you're acting depressed, mopey, or sulky. Make sure you're laughing and genuinely trying to have a good time. You might find that you've become a happier person along the way.
If you are feeling depressed, surround yourself with friends or family. Don't wait alone in a corner and just hope for her to come back to you. Develop a playful sense of humor. What do girls say they look for most in guys? A sense of humor and a playful attitude These two traits are attractive because they tell other people that we're youthful and not aggressive. So learn a few jokes if you can friends are always good to try them out on and keep the ones that work and throw away the ones that don't.
Learn to make fun of yourself a little, in a confident way — not a mopey way. And, for goodness sake, be playful, especially when you're around her. Tease her lovingly, or play a small prank on a friend. You'll notice the difference in her. Method 2 of Leave her alone. At least for a little while, give her some time to think about the relationship. If you had a great relationship, she'll think about all the good things that you did for her and feel the absence of you in her life.
Cut off all communication. Maybe you don't talk to her for a couple weeks, or perhaps a month. This is tough and it will hurt, but really it's killing her more. This will also let your tempers cool down if things were heating right when you broke up. You need to give her space for three reasons: 1 People simply need space; if you can't give her any space, maybe that's something you can work on to show her that you've changed.
Start talking to another girl. Don't do anything with her, but strike up a friendship. You want to raise your own stock by showing her that other girls like you and are attracted to you. Don't get this step confused with pursuing another girl. You want to hang out and talk, do fun things together, but not hook up. If you hook up with another girl, your chances of getting back together with your ex are greatly diminished. Go out with a group of girls. Show your ex that attentive girls like being around you.
These girls will be your wing-women. If you can pull together a big group of popular, intelligent, smart girls, chances are your ex is going to feel more interested, maybe without even noticing it. Tap your inner alpha male. The alpha male, in nature, is the male in a group of primates that has the highest rank, and gets his pick of the females. Even if you don't think that alpha males are your ex's type, subtle changes might work on her: pump out your chest a bit, make an effort to work out your arms and thighs, and project strength.
Method 3 of Give her an apology. Whether you broke up with her, or she broke up with you, an apology is almost always in order. An apology shows her that you're capable of swallowing your ego, and that you care enough to tell her you were wrong. If done correctly, an apology will work wonders. Send her flowers.
10 ways to get your ex-girlfriend back
For many people, a familiar unhappiness is better than an unfamiliar one. But is getting back together really such a great idea? In order to understand whether getting back together with an ex is a good idea, AskMen spoke with several dating experts, as well as some people who got back together with their exes. Tessina, Ph. Romance's Guide to Finding Love Today.
The relationship you had is OVER and will not magically return due to any trick, gimmick, text message or clever conversation. While it is possible to learn how to get your ex back and re-enter into a new relationship with her…a relationship where you have both learned, grown, and improved…this new relationship will be markedly different from the love you had before. If done right, it can be better…but it will not be exactly like the love you had before. A man who has shed the unattractive and beta behaviors of the past and shifted into a more empowering mindset and a stronger more Grounded Man.
How To Get Your Ex Girlfriend Back – Why Most Lose Even When They Win
You only get a handful of chances. And if you are not prepared, you will screw it up. If you want to get your ex girlfriend back, you need to take this as a mission. Almost like a video game. If asking her to get back together is the final fight in this game, you need to level up and win a lot of mini fights before doing that. But first, let me introduce myself and tell you a bit about why I am writing this. Read more about me and this website here. This article is everything I wish I had access to when I had my first breakup and wanted to get my ex girlfriend back. When I woke up in the middle of the night crying and feeling lonely, with no one around me to give me good advise. Always wondering if I have a chance get her back.
How to Get Your Ex-Girlfriend Back
I talked with lots of my friends and dating gurus before locating Michael Fiore regarding how to get an ex girlfriend back. He talks about important aspects of a healthy relationship that I feel my relationship was missing. I knew it is easy to get likes on your Youtube video but the interaction and feedback he was getting from his audience seems real dude to me. After couples of meetings on Facebook, I decided to visit his place as he was at my hometown Vancouver, BC, Canada at that time. In my one-to-one meeting I asked lots of question about how to get an ex girlfriend back and lot of other stuff on female psychology.
My most powerful strategies are in my Emergency Breakup Kit. It contains advanced strategies based on Ph. Even if they got their ex back, do they know how and why based on scientific principles or is it just what they think worked.
Can You Get Your Ex-Girlfriend Back?
Every single relationship is different. The truth is, even the smallest of habits we see as no big deal, such as leaving a toilet seat down can drive a woman to want to run out the door. She might not speak up about it, however, perhaps she still feels strongly about it.
You made a huge mistake when you let her go. You want to do this right, and that means re-engaging with an abundance of caution and more confidence than ever. Sometimes absence makes the heart grow fonder—but other times, it causes that heart to seek out another man. Brought back memories of the concert together. If she responds, she may be open to rekindling the spark. So propose getting together—not moving in together.
How To Get Your Ex Girlfriend Back By LEVELING UP – Game Plan in 5 Stages (And 17 Missions)
Have you ever hated someone and then really liked them later on when they changed the way that they communicated or behaved around you? When you begin saying and doing things that make her feel respect and attraction for you, she will naturally begin to feel differently about you. Right now, your ex might not have much or any feelings for you to want to get back into a relationship. In most cases, all it usually takes is a spark of attraction and woman immediately becomes more open to communicating with her ex and even meeting up with him in person. As long as you are interacting with her and sparking her feelings of respect and attraction for you, her guard will come down and you can then guide her back into a relationship and get her back for good.
Has your girlfriend broken up with you? Not so long ago my girlfriend dumped me just the same. Amazingly though, a few months later, we were and are back together and engaged. The approach we will take on how to make your ex want you back will depend on WHO initiated the breakup.
How To Get Your Ex Back After A Breakup: A Method That Actually Works
By Chris Seiter. Now, I am not saying that it is impossible to get her back. On the contrary, if you play your cards right then you can drastically improve your chances of winning her back.
How to Get Your Ex Girlfriend Back: Step By Step How to Win Her Back Revealed
Despite the lyrics to any Taylor Swift song , breakups don't always have to be permanent, and exes tend to get back together more often than you think. At the same time, reuniting with a partner doesn't have to be one person desperately wooing the other back in true rom-com fashion. In fact, seeing a reconciliation as anything other than a combination of mutual growth and effort is a pretty unhealthy approach.
Best Ways to Get Your Ex Back
How to Get Back Together With Your Ex
Earlier I thought differently, I thank for the help in this question.


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This entry was posted in Patio on June 20, 2016
Decorating your patio is an opportunity to show your personality, and create a special place to host gatherings, games, and solo sessions with a glass of wine and a best seller.
Studies show spending time outdoors makes you a happier person. With a carefully decorated and planned patio, you can create a space to cater to any activity you love.
Once you have your space just the way you want it, you need to start thinking about how to maintain it! Prone to dust, dirt and other outdoor debris, patios get dirtier than any other area in our homes. Below are a few tips for keeping your patio space in top-notch shape so you can enjoy it all summer long.
Sweep, then soak. When doing a thorough clean of your patio (which you should do at least once a year at the beginning of the summer season), sweep off everything you can first. Then hose down the patio flooring with mild detergent (or another cleaning solution of your choice) and water.
Know your patio well. Different patio materials require different maintenance and methods of cleaning. When purchasing patio flooring, make sure to ask the sales associate what tips they have for keeping it clean and making it last as long as it can. Search online for your patio material as well, and you can find numerous guides for how to take care of the flooring.
Schedule a weekly cleaning. Make sure you have a small weekly cleaning session on the calendar – and stick to it. Use this time to clear off outdoor debris like leaves, dirt, stray flowers, etc.
Take care of your furniture too. Make sure you're washing patio cushions every few weeks. Always bring them inside when you're expecting rain. Cushions develop mold easily, and once they do, you won't be able to reuse them. Another often-neglected patio item is umbrellas. These need to be cleaned thoroughly with detergent and water once or twice during the summer.
Patio maintenance is much easier than most people think. If you take the time to do a deep clean of your space at the beginning of the summer and then schedule weekly smaller cleanup sessions, you can keep your patio looking as new as the first day you designed it. Don't let your dream space become a home for leaves, soil, and animal droppings. With these simple tips, you'll have a lovely place to hang out in all summer long.
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Switzerland County High School will celebrate its Winter Homecoming tomorrow (Friday) with a home basketball game against New Washington.
As is tradition, between the junior varsity and varsity games, this year's Homecoming Queen and King will be crowned. Members of the senior class were chosen as members of the Homecoming Court, with the student body then voting on the winners.
First and second runners up will also be crowned, and the new royals and their court will reign over the varsity game and the dance that will follow in the cafeteria.
This year's Homecoming Queen candidates include:
— Matty Anderson is the daughter of Tully and Cindy Anderson of Florence. During high school, she has been a member of the soccer, track, and cross country teams. Matty was a three-time regional qualifier in the 3,200-meter relay and a regional qualifier in cross country during her junior year. She was the Madison Courier Girls Soccer Player of the Year and a three-time all-conference selection.
Matty earned All-Sectional during her senior year of soccer when her team won the conference championship. She is also a member of the Pep Club, where she serves as the communications director and serves as the vice president of the National Honor Society.
After graduation, Matty plans to enter the United States Air Force, where she will begin her career in cybersecurity.
— Aliyah Begley is the daughter of Karen and William Begley of Vevay. During high school, she has been a member of the softball and soccer teams. She is also an active member of Student Council.
Aliyah has volunteered her time at the Switzerland County Animal Shelter, the Swiss Villa Nursing Home, and the Lantern Coffeehouse. She was also selected for the Junior Leadership Program and holds a full time job at Belterra.
After graduation, Aliyah plans to attend Indiana University Bloomington to pursue a career in biomedical engineering.
— Allison Detmer is the daughter of Allen and Michelle Detmer of Patriot. During high school, she has been a member of the cross country and track teams. Allison has also participated in Drama Club and National Honor Society.
She is the president of Student Council, the co-president of Key Club, the president of the Art Academic Team, and president of the Posey Pioneers 4-H Club. Allison also volunteers her time as a member of the Hoosier Theater Board. She was awarded the ORVC Cross Country Mental Attitude Award and the National Academy Future Scientists and Technologists Award of Excellence.
After graduation, Allison plans to pursue a degree in computer science.
— Ally Furnish is the daughter of Raymond and Stephanie Furnish of Vevay. During high school, she has been a member of the volleyball, swimming, and track and field teams. In volleyball, Ally was an Indiana Academic All-Star and a three time all-conference and all-sectional award winner. In swimming, she holds every female record. In track and field, Ally was a three-time regional qualifier in the 300 hurdles.
She has also participated in Student Council, National Honor Society, and Drama Club. Ally is also the treasurer of Key Club and her senior class. She volunteered her time on the community spray paint mural and currently works as a lifeguard at the YMCA.
After graduation, Ally plans to attend Trine University and major in cybersecurity.
— Josie Meyer is the daughter of Melissa and Mike Meyer of Vevay. During high school, she has been a member of the basketball, track, cross country, and golf teams. Josie is also an active member of the Pep Club. She has volunteered her time coaching at the YMCA Girls Basketball Camp and running the clock at several youth basketball games. In basketball, Josie earned awards for the most three pointers, the best defense, and the most improved player.
She was also named the top student in Building Trades 1 and 2.
After graduation, Josie plans to attend Northern Kentucky University to study business, where she will be working towards her dream of owning her own construction company.
— Destine Peelman is the daughter of Darrell and Beverly Peelman of Vevay. During high school, she has been a member of the cheer and track teams. She has also participated in Pep Club, Key Club, and Spanish Club. Destine is a three-time cheerleading state finalist, a member of two track conference championship teams, and a volunteer at Sleepy Hollow.
She currently works as a CNA at Swiss Villa and Manderley Health Care Center and is a part of the Bridge Youth Ministry at the River.
After graduation, Destine plans to enter the United States Air Force.
This year's Homecoming King candidates include:
— Logan Bennett is the son of LuAnn Bennett of Patriot and the late Bruce Bennett. During high school, he has been a member of the basketball team, Pep Club, and Conservation Club.
He enjoys spending time with his friends and working at Roxano's Italian Restaurant.
After graduation, Logan plans to attend Indiana University in Bloomington to pursue a career as an anesthesiologist.
— Damian Breeck is the son of Christian Breeck, and the grandson of Doug and Julie Brown of Vevay. During high school, he has been a member of the basketball, soccer, and baseball teams. Damian has also been a part of the Iron Sharpens Iron Club. He earned all-conference honors in basketball his junior year and all-conference honors in soccer his senior year.
He was also named one of the top 100 underclassmen basketball players after his sophomore and junior seasons.
Damian is undecided on what career he wants to pursue after graduation.
— Trey Gray is the son of Tracy and Tammy Gray of Vevay. During high school, he has been a member of Drama Club and the Social Studies and English Academic Teams. Trey was also the junior class vice president, a member of the prom committee, and is currently the president of the FFA and the vice president of his class. He has volunteered his time at the Lions Club booth at the Swiss Wine Festival and the Lions Club Golf Scramble. Trey was also part of campaign calling for the Greg Pence congressional race and helped maintain plants around Vevay over the summer.
He was a Swiss Wine Festival 2019 Swiss Ambassador and earned his FFA State Degree. Trey is a district FFA Historian and was a page at the Indiana Statehouse. He is also a member of Long Run Baptist Church.
After graduation, Trey plans to pursue a degree in Agriculture Education to prepare for a career as an agriculture teacher.
— Sam Herald is the son of Jennifer Mathews of Vevay and Darin Herald of Bedford, Kentucky. He has had perfect attendance throughout several years in his high school career.
He attends Poplar Ridge Baptist Church and enjoys quoting lines from various different movies.
After graduation, Sam plans to pursue a degree in chemistry at Ivy Tech and later obtain a job at the Clifty Creek Power Plant.
— Patrick Stow is the son of Tom and Missy Stow of Vevay. During high school, he has been a member of the baseball team and was a part of the sectional championship team in 2018.
Patrick was recognized as all-conference and all-sectional during the 2018 baseball season. He has also participated in FFA and has earned many awards and titles including his state degree this past year.
After high school, Patrick plans to attend Ivy Tech in Columbus, Indiana, to pursue a degree in agricultural business which he will use to become the co-owner of his dads company, Final Grade.
— Landon Wilks is the son of Anthony and Lisa Wilks of Vevay. He is a member of the basketball team, where he currently serves as a captain. Landon is also a member of the DistinXion AAU Basketball Club.
He spends time outside of school as an active member of his church. He is a member of the Bridge Youth Group, the National Youth Convention, and a volunteer at the community food pantry.
Landon is undecided on what career he wants to pursue after graduation.


text: 03 Jul IBM Adversarial Robustness Toolbox Helps to Protect Neural Networks Against Malicious Attacks Posted at 09:05h in Jesus Rodriguez by ywkl 0 CommentsThe open source framework provides best practices to defend deep neural networks against adversarial threats.Mar 9 . 6 min readDeep neural networks(DNNs) are rapidly achieving a level of sophistication that is dazzling even the most optimistic technologists in the space. However, with sophistication have come a lack of interpretability of DNN models and with that come risks. If we can't understand what a DNN is doing, how can we possibly protect it against potential vulnerabilities. Not surprisingly, sophisticated DNNs have proven to even extremely vulnerable for the simple manipulations in the models and training datasets. Generative adversarial neural networks(GANs) have emerged as one of the fundamental techniques to attack DNNs. The raised of GAN-based attacks have forced machine learning specialists to regularly evaluate the robustness of DNN models. IBM has been one of the most active companies in this area and, about a year ago, compiled some of its findings into an open source framework known as the adversarial robustness toolbox.Generative adversarial neural networks(GANs) are one of the most active areas of research in the deep learning ecosystem. Conceptually, GANs are a form of unsupervised learning in which two neural networks build knowledge by competing against each other in a zero-sum game. While GANs are a great mechanism for knowledge acquisition, they can also be used to generate attacks against deep neural networks. In a very well-known example, a GAN attacker can cause imperceptible changes in training images to trick a classification model.The topic of evaluating the robustness of models against adversarial attacks have been a top priority of AI powerhouses such as OpenAI or Google. A bit under the radar, IBM has been doing a lot of work trying to advance the research and implementation of adversarial attacks in deep neural network. Just last week, IBM AI researchers published two different research papers in the area of GAN protection. Today, I would like to explore some of IBM's recent work about protecting neural networks against adversarial attacks and discuss its relevance in modern deep learning implementation.Adversarial attacks against deep neural networks can be classified in two main groups: White-Box and Black-Box based on their knowledge of the model's training policy. The white-box adversarial attacks describe scenarios in which the attacker has access to the underlying training policy network of the target model. The research found that even introducing small perturbations in the training policy can drastically affect the performance of the model.Black-box adversarial attacks describe scenarios in which the attacker does not have complete access to the policy network. In AI research literary, black-box attacks are classified into two main groups:1) The adversary has access to the training environment and knowledge of the training algorithm and hyperparameters. It knows the neural network architecture of the target policy network, but not its random initialization. They refer to this model as transferability across policies.2) The adversary additionally has no knowledge of the training algorithm or hyperparameters. They refer to this model as transferability across algorithms.A simpler way to think about white-box and black-box adversarial attacks is whether the attacker is targeting a model during training time or after is deployed. Despite that simple distinction, the techniques used to defend against white-box or black-box attack are fundamentally different. Recently, IBM has been dabbling into both attack models both from the research and implementation standpoint. Let's take a look at some of IBM's recent efforts in adversarial attacks.The Adversarial Robustness Toolbox(ART) is one of the most complete resources for evaluating the robustness of deep neural networks against adversarial attacks. Open sourced by IBM a few months ago, ART supports incorporates techniques to prevents adversarial attacks for deep neural networks written in TensorFlow, Keras, PyTorch and MxNet although support for more deep learning frameworks should be added shortly.ART operates by examining and clustering the neural activations produced by a training dataset and trying to discriminate legit examples from those likely manipulated by an adversarial attack. The current version of ART focuses on two types of adversarial attacks: evasion and poisoning. For each type of adversarial attack, ART includes defense methods that can be incorporated into deep learning models.Developers can start using ART via its Python SDK which doesn't require any major modifications in the architecture of the deep neural network.A large percentage of the adversarial attacks against deep neural networks are produced in a white-box setting in which the attacker has access to the network's training policy. Black-Box attacks are both more challenging to implement as well as more difficult to defend against them. For instance, a black-box attack against an image classification model typically needs to execute a large number of queries against the model in order to find the correct adversarial images. Many times, those queries cause a performance degradation in the model that have nothing to do with the attack itself but with the network's poor design for high volume queries. For instance, in the following image, the black-box adversarial attack takes more than 1 million queries to find the adversarial image. That level of computational resources are rarely available to attackers.IBM's Autoencoder-based Zeroth Order Optimization Method(AutoZOOM) is a technique for creating more efficient black-box attacks. Initially published in a research paper, AutoZOOM also includes an open source implementation that can be used by developers across several deep learning frameworks. The goal of AutoZOOM is to accelerate the efficiency of queries targeting adversarial examples and it accomplishes that using two main building blocks:i. An adaptive random gradient estimation strategy to balance query counts and distortion.ii. An autoencoder that is either trained offline with unlabeled data or a bilinear resizing operation for acceleration.To achieve i, AutoZOOM features an optimized and query-efficient gradient estimator, which has an adaptive scheme that uses few queries to find the first successful adversarial perturbation and then uses more queries to fine-tune the distortion and make the adversarial example more realistic. To achieve ii, AutoZOOM implements a technique called "dimension reduction" to reduce the complexity of finding adversarial examples. The dimension reduction can be realized by an offline trained autoencoder to capture data characteristics or a simple bilinear image resizer which does not require any training.The initial tests of AutoZOOM showed that the method is able to generate black-box adversarial examples with a far fewer queries than traditional methods.As you can probably tell from the examples, convolutional neural networks(CNNs) used for image classification are among the top targets of adversarial attacks. However, many of the current defense techniques are not optimized for CNN architectures. Created by AI researchers of the Massachusetts Institute of Technology(MIT) and IBM, CNN-Cert is a framework for certifying the robustness of CNNs against adversarial attacks.The key innovation in CNN-Cert is deriving explicit network output bound by considering the input/output relations of each building block. The activation layer can be general activations other than ReLU. The approach demonstrated to be about 11 to 17 times more efficient than traditional adversarial robustness certification methods. CNN-Cert is able to handle various architectures including convolutional layers, max-pooling layers, batch normalization layer, residual blocks, as well as general activation functions such as ReLU, tanh, sigmoid and arctan.As you can see, IBM seems to be really committed to advance the conversation about adversarial attacks in deep neural networks. Efforts like ART, AutoZOOM and CNN-Cert are among the most creative recent efforts in adversarial techniques. Hopefully, we will see some of these implementations included in mainstream deep learning frameworks soon.


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In the past people used to travel on their feet and that method has turned out to be into many ways. Now people have the liberty to use airways as well. Planes have adapted many sources to their wills and the technology is being developed day by day. Here are 10 amazing factors you love to know about airbus.
It is not the biggest
Though people have a belief that airbus is the largest man-made thing in air, it is not. Because they have a competition with Anatanov and that party could win the contest by having the largest plane in air. An-225 was the one won the contest.
It is said that the wiring has been an amazing thing to discuss on airbus series. Even though it is about an electrical engineer, it might take up to months to have a better understanding about the electrical system. If you are wondering how much to know, the length of it is about 320km.
Most orders
Though how much bigger the Antanov series, airbus has already touched the hearts of all levels. Airbus series has received $72.2 billion worth orders from the aviation authorities around the world because its attractive features. It is a record as well.
Though the airbus has not been the largest one with wings, it is considered as the largest civil aircraft on Earth. It weighs 560tons with a length of 72m from front to back. There are 200 windows for the passengers and the crew to look at the clouds from the sky. It is said that 6000 engineers have worked on this project.
Airbus Defense
There is a defense department inside the Airbus Company that do researches and tests for defense purposes. They are planning to produce a new supersonic jet for defense purposes. Aerion AS2, supersonic jet to be produced will be released in 2021.
The first flight
Singapore Airlines was the first one to call for an order for a super-giant passenger plane. They had their order from airbus and that flight was scheduled from Singapore to Sydney. There were 450 passengers in that flight. It was a memorable moment for Sydney airport as well. They had to expend $128 to improve the infrastructure in the airport. Special air bridges had to be created because of the highest figures of this jumbo jet.
Not so common
It was a thing that all the airports around the world needed to be aware after the Sydney incident, not having enough resources to land this giant bird on their runways. Some of the authorities identified the necessity of a large runway as a future investment. So, now there are 20 runways and the relevant infrastructure for landing an A380 in their airport runways.
Life time
There is a particular lifetime for any good in the world. 140,000+ fly hour range has been guaranteed for this giant bird which means it can have 2000 flights all around the world. That means a huge value when comparing with other related brand in the world.


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Grief Is the Thing with Feathers
Max Porter (Author) Jot Davies (Narrated by)
DescriptionHere he is, husband and father, scruffy romantic, a shambolic scholar-a man adrift in the wake of his wife's sudden, accidental death. And there are his two sons who like him struggle in their London apartment to face the unbearable sadness that has engulfed them. The father imagines a future of well-meaning visitors and emptiness, while the boys wander, savage and unsupervised. In this moment of violent despair they are visited by Crow-antagonist, trickster, goad, protector, therapist, and babysitter. This self-described "sentimental bird," at once wild and tender, who "finds humans dull except in grief," threatens to stay with the wounded family until they no longer need him. As weeks turn to months and the pain of loss lessens with the balm of memories, Crow's efforts are rewarded and the little unit of three begins to recover: Dad resumes his book about the poet Ted Hughes; the boys get on with it, grow up. Part novella, part polyphonic fable, part essay on grief, Max Porter's extraordinary debut combines compassion and bravura style to dazzling effect. Full of angular wit and profound truths, Grief Is the Thing with Feathers is a startlingly original and haunting debut by a significant new talent.
Product Details
$19.99 $18.39
Tantor Audio
Publish Date
October 31, 2017
2.2 X 0.6 X 9.8 inches | 0.1 pounds
BISAC Categories:
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About the Author
Max Porter works in publishing. He lives in South London with his wife and children. Grief Is the Thing with Feathers is his first book.
Jot Davies is a television and voice actor who recorded dozens of audiobooks, including Ben Goldacre's Bad Pharma and multiple works by Charles Cumming and Paul Strathern. In reviewing his narration of A Foreign Country, AudioFile magazine praises, "Davies's narration ushers you in" and his "pacing fits the narrative," calling his voice "a steady presence through the disparate events from the beginning to the satisfying conclusion." Outside of narration, his acting credits include television shows Casualty, New Tricks and Hotel Babylon and the video game Haze.
"[A] remarkable debut . . . Like a prose poem in its splendid language but with its own swift flow, this is highly recommended for ambitious readers." ---Library Journal Starred Review


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Categories: General, Publications and Resources
Hi Daffnetters
The NZ Annual was delivered yesterday just in time for the cold snap that's hit the area today- It's 5'C and hail is falling outside – good indoor weather for watching the Olympic Games replays.
How lovely to be able to relax and read the descriptions and impressions from so many people who attended the recent Australasian and World Daffodil Conventions. Dr Keith Hammett's article is thought provoking too and I'm saving the rest of the magazine for later. A big thankyou to everyone who contributed.
Are you sure you want to relinquish the position of editor Peter? It seems to me that you're just getting into your stride so to speak. The illustrations and photos are a delight as is 'Digging Tony's daffodil patch'.
Many thanks
Margaret Seconi
Wellington NZ


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More 60's inspiration. I love this set, unique and full of texture! Made of a nylon stitched to create a rose pattern and trimed with a tiny bow. The little cap tops it off perfectly!
Head over to Ammunition Couture to check out the awesome accessories and latex pieces paired with this mini collection.


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7MP file extension
The table below provides useful information about the .7mp file extension. It answers questions such as:
- What is the .7mp file?
- What program do I need to open a .7mp file?
- How can the .7mp file be opened, edited or printed?
- How can I convert .7mp files to another format?
Table of Contents
- ✅ SafeNet MP-1 Token Data
- 🔄 .7mp file converters
- 🚫 .7mp file related errors
We hope you find this page helpful and a valuable resource!
1 extension(s) and 0 alias(es) found in database
✅ SafeNet MP-1 Token Data
7MP file is a SafeNet MP-1 Token Data. SafeNet MP-1 Tokens are software tokens that transform a user's computer into a one-time password (OTP) generator.
Other types of files may also use the .7mp file extension.
🚫 The .7mp file extension is often given incorrectly!
According to the searches on our site, these misspellings were the most common in the past year:
Is it possible that the filename extension is misspelled?
We found the following similar file extensions in our database:
🔴 Can't open a .7mp file?
When you double-click a file to open it, Windows examines the filename extension. If Windows recognizes the filename extension, it opens the file in the program that is associated with that filename extension. When Windows does not recognize a filename extension, you receive the following message:
Windows cannot open this file:
To open this file, Windows needs to know what program you want to use to open it...
If you don't know how to set the .7mp file association, check the FAQ.
🔴 Can I change the extension of files?
Changing the filename extension of a file is not a good idea. When you change a file's extension, you change the way programs on your computer read the file. The problem is, changing the file extension does not change the file format.
If you have helpful information about the .7mp file extension, write to us!
🔴 Rate our 7MP page
Please help us by rating our 7MP page on a 5-star rating system below. (1 star is poor, 5 star is excellent)


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Inviting 4 Bedroom Home, PLUS a Loft & 3 Full Baths…. Spectacular Pool & Spa…. On a Quiet Cul-de-Sac Street. Customized & Meticulously Maintained by the Original Owners. Wonderful Indoor and Outdoor Living….Minutes to the Beach! Sunny Two-Story Living Room, w Vaulted Ceilings & Decorator Tile Flooring, focuses on a Cozy Fireplace accented by Handcrafted Cabinetry & Mantel. Sparkling Kitchen boasts Custom Cabinets, Granite Counter Tops, Stainless Steel Appliances & Huge Breakfast Island with Added Storage…. Even a Wine Rack. Kitchen opens to a Large Flagstone Cabana Area & Spectacular Pool & Spa, for entertaining or just vacationing at home! ….Downstairs Bedroom & Full Bath is perfect for "Mom" or Guests. Upstairs, there are 3 Bedrooms, 2 Full Baths… AND a Study Loft. Spacious Master Suite has Cathedral Ceiling, Ceiling Fan/Light, Custom Wall Covering, Mirrored Wardrobe Doors & Generous Master Bath. Two Additional Bedrooms include…. Large Loft, w Built-In Desk, overlooks the living room, makes a Great Den, Kid's TV Room or Home Office. Features: *Friendly Front Porch *Custom Tile & Hardwood Flooring *Decorator Ceiling Fans & Lighting *Vaulted Ceilings *Glass Tub Enclosures *Mirrored Wardrobe Doors *Custom Woodwork & Wall Coverings *Flagstone Covered Porch & Patio *Spectacular Pool & Spa. Come home from the beach to Sit by the Fire…. Enjoy the warmth & comfort of indoor living, or…. Take a swim…. Relax in your spa…. Hangout on your Patio…. VACATION at HOME!
Listing courtesy of John Williams from Harcourts Prime Properties
Listing sold by Gabe Cole from Compass


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Class Schedule
Spa Services
Contact Us
Kindred Yoga & Wellness
Your guides to relaxation...
Yoga Instructor & Co-Owner
Kim's love of yoga began in 1991, when she first started taking classes in the basement of a local church in her home-town of Cedar Rapids, Iowa. She has paricipated in many styles of yoga over the years before deciding to become a yoga teacher herself. Finding a Yoga Alliance approved training that focused on yoga from a Christian perspective was a dream come true! Kim completed her RYT-200 in Tempe, AZ at Yahweh Yoga and began teaching in early 2018. Kim is currently working toward her RYT-500 at AYC in Ashville, NC and is excited to share all she is learning about different styles of yoga in her classes at Kindred Yoga & Wellness
Yoga Teacher & Co Owner
Yoga Teacher
Lannie, an Air-force Veteran, spent many years traveling the world, finding himself. While in the service he found his love for yoga. He found that the military workouts that he lead and participated in were hard on his body and that he needed to nourish and take care of his body. He did this with Yoga and meditation. Lannie started with at home vidoes and soon after began finding sequences of his own that he would practice. After many years of self practice Lannie took the 200 hour YTT program in Statesborro, Georgia. Lannie enjoys teaching restorative and Yin.
Yoga Instructor
Shelby is originally from Omaha, Nebraska where she found her passion for yoga. Shelby found yoga at YMCA in high school and has practiced since. In Colorado, her love of yoga grew even more. After just marrying her husband, Lannie, they decided to move to Metter, Georgia and get serious about yoga. Shelby has her 200 hour yoga teacher certification in Statesborro, Georgia. Shelby enjoys teaching any flow classes and guided deep meditations.


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Pop quiz for you.
A genetically enhanced super soldier has given you very clear instructions as she has you hanging by your feet over the balcony of a high rise skyscraper with tons of asphalt and concrete below ready to give you a very bloody and final kiss if you dont answer and repeat a very important question.
Do you understand? Repeat it.
Well, yes I understand can be the only correct answer.
While other 19 year olds are walking around college with loans as heavy as their back packs, Jessica Alba was starring in the TV series Dark Angel with a ton of money in her back pack.
Very prophetic.
Soon youll see what we mean.
Dark Angel is an American television series that premiered on the Fox network on October 3, 2000.
It was created by James Cameron and Charles H. Eglee, starring Jessica in her breakthrough role.
Set in 2019, the series chronicles the life of Max Guevara (Alba), a genetically enhanced super-soldier who escapes from a covert military facility as a child. In a post-apocalyptic Seattle, she tries to lead a normal life, while eluding capture by government agents and searching for her brothers and sisters scattered in the aftermath of their escape.
Talk about a walk down memory lane.
Jessica, now 36, went on to a blockbuster Hollywood career and if she chooses to, can not only walk around with a ton of Hollywood money in her back pack, she can also tote around a ton of entrepreneurial business cash as well.
Our gorgeous star with mesmerizing sad and beautiful eyes began her television and movie appearances at age 13 in Camp Nowhere and The Secret World of Alex Mack (1994).
She later appeared in Honey (2003), Sin City (2005), Fantastic Four (2005), Into the Blue (2005), Fantastic Four: Rise of the Silver Surfer (2007) and Good Luck Chuck (2007).
One of her later gems that audiences loved was when she took a risk and appeared in 2010s The Killer Inside Me as an aggressive prostitute who brings a Texas lawman's (Casey Affleck) homicidal tendencies screaming to the surface.
Very, very sexy role.
Jessica has evolved into a business mogul as well.
Did you know that?
In January 2012, Alba co-founded The Honest Company, a consumer goods company that sells non-toxic household products, and owns 15 to 20 percent of the company.
The Honest Company is an American consumer goods company that emphasizes household products to supply the marketplace for ethical consumerism.
The company had $170 million in 2014 sales and was valued at $1.7 billion as of August 2015.
The Honest Company has raised multiple rounds of venture capital and was anticipating an initial public offering as of 2016.
The company serves the United States and Canada.
We are so impressed we wanted to visit then. At their warm and receptive site honest.com they smile, Our story began with a simple desire: to make the right choices for our families. We were parents in search of safe options, but unsure of where to turn. We needed one brand that we could go to for trusted products and information. And when we couldn't find what we were looking for and realized we weren't alone the idea for Honest was born.
We're a wellness brand with values rooted in consciousness, community, transparency and design. And we're on a mission to empower people to live happy, healthy lives. Every day and in every way, we hold ourselves to an Honest standard. Because we believe that what you put on, in and around your body matters. A lot.
What a great philosophy. It certainly has won over thousands of customers. A lot.
It always helps when the sensuous and talented Jessica speaks on screen on in the board room. Regarding the Honest Company she adds, I founded The Honest Company because I wanted safe, effective products that perform. After all, you shouldn't have to choose between what works and what's good for you.
Very honest.
Very good point.
Jessica is scoring business points elsewhere as well.
When she forms business partnerships, the announcement trumpets come at. On February 22, 2017 at the global news and information source telegraph.co.uk they reported, Jessica Alba, an American actress known for her roles in blockbusters such as Sin City and Fantastic Four, as well as the founder of baby skincare brand The Honest Company, has joined Rosewood Hotels & Resorts as a brand curator.
The hotel group's curators are a carefully selected group of luminaries and leaders who share travel tips and insider secrets for Rosewood destinations around the world.
Sounds intriguing. Lets pack a suitcase and meet them.
Smiling with open arms at their hospitable site rosewoodhotels.com we are delighted.
Rosewood Hotels & Resorts is an international luxury hotel and resort company operating 19 properties in 11 countries, owned by Hong Kong-based New World Development.
Ms. Caroline Rose Hunt founded Rosewood in 1979, desiring to create residential-style luxury hotels that would provide guests with attentive personalized services. A year later, she converted the mansion of Texas cotton magnate Sheppard King into Rosewood's first hotel, The Mansion on Turtle Creek, located in the upscale Turtle Creek neighborhood.
The rest as they say is international history.
Jessica offers advice on the Riviera Maya in Mexico, one of her favorite places to holiday with her family, and the location of Rosewood Mayakoba, a luxury Mayan-inspired resort with private plunge pools, floating villas and eco credentials, located north of Playa del Carmen.
As far as back packs go, talk about going green? Thats the kind of green that really looks and tastes good.
What makes her triumphs even more admirable is that our sensuous fresh faced beauty hasnt always had it easy.
Her early life was marked by a multitude of physical afflictions.
During her childhood, she suffered from partially collapsed lungs twice, had pneumonia four to five times a year, as well as a ruptured appendix and a tonsillar cyst.
Yet she endured.
Jessica excelled and graduated from high school at 16.
She sure has come a long way since then.
At the entertainment industry site imdb.com they report that she paid $4,050,000 for a 4,686-square-foot house in Beverly Hills, California.
Part of her success was due to her determination to have a better life after her parents married early at 20 and financially struggled.
When we first saw her in Dark Angel, we knew that she was extremely beautiful, talented and could attract and mesmerize a crowd, have fans fall in love with her and had a bright future in Hollywood.
Her phenomenal business success came as a surprise to some.
It shouldnt have though.
In an interview she reveals at least the foundation for some of her success. I wasn't given a whole lot in my life. I was on the bottom of the class system. But I got wisdom. I never just did what people told me. I questioned everything. When I look back, it is really no surprise that I started working at 12.
Looking back, it is really no surprise that she continues to shine and have a positive impact on the world as an angel of light.
~ ~ ~
OPENING PHOTO fciwomenswrestling.com article, photo via Youtube


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Know how to apply FASTag for Toll Payment with Lowest Fees comparison from ICICI Bank, HDFC and Paytm with Process, Fixing, Common Queries answered
Fast Tag (FASTag) for Toll Payment
FASTag (hereafter referred as Fast Tag) in layman terms is a process through which toll payments on national highways can be done electronically. In this Fast tag sticker will be affixed on car windshield, when the car crosses in National Highway and passes through FASTag lane – the RFID reader will automatically scan the RFID without any need of stopping the car on toll booth for payment of toll
The RFID Technology automatically detect the tag and the toll amount will be debited from the Fast Tag balance. Its like having a prepaid account where the tolls are automatically deducted when ever the car crosses in the Toll booth
Direct Benefits of FASTag
- No Queing at the Toll Booth. A Fast way of making payments digitally for passing toll booth
- No Stopping of Car, No Cash Payments. Saves Time, Fuel
- Saves Manpower Cost of Collection of Toll
Deadline for FASTag: Now every Toll Plaza is equipped with RFID Scanner and deadline extended to 15th December 2019. Earlier it was 1st December 2019. FASTag is Mandatory at all Toll Plaza. Vehicles without FASTag sticker will be required to pay Double the Scheduled Toll rates in Cash.
How Fastag is Obtained with Fees
The Fast Tag can be enrolled in through any
- NETC (National Electronic Toll Collection) Toll Plaza selling Fast Tag Sticker.
- Banks like ICICI Bank, HDFC Bank, Kotak Bank selling FASTag
- Other Wallet like Paytm Payment Bank
Payment Details for Issuance of FASTag
|ICICI Bank
|HDFC Bank
|FASTag Fee
|Rs 100
|Rs 100
|Security Deposit
|Rs 250
|Rs 200
|Rs 200
|Minimum Balance
|Rs 150
|Rs 200
|Rs 100
|Net Minimum Payment
|Rs 400
|Rs 500
|Rs 400
** - Limited Period Offer
Additional Convenience Fee: 1% to 1.1% of Transaction Value by HDFC Bank. ICICI Bank charges 1.8% on recharging through Credit Card and from .2% to .85% through Debit Car or from 1% to 1.65% through Net Banking. Paytm also charges same. However no Fees on UPI Payment been charges by some of these
You can visit respective Bank Website or Paytm app for applying for FASTag and paying fees. Important is to have Vehicle RC / Smart Card Photo available to upload it along with it and update details on website
Special for ICICI Bank Account Holder: Those using the ICICI mobile app can order their tags through the app with no additional kyc. Once you give vehicle number the app it gets your other details from vahaan and displays for payment. The tag is activated within hours and dispatched in two days.
Recharge Amount: If you pay Rs 1000 in beginning - then it will give Rs 600 as recharge amount in FASTag with ICICI Bank, Rs 700 with HDFC Bank, Rs 750 with Paytm
It can take upto 7 working days to get the tag after applying. Important to note that Every Vehicle (Car, 2 Wheeler, 3 Wheeler, Truck or Bus) needs a separate FASTag
How to Affix Fast Tag on Windshield: Once received - you need to apply FasTag on Center Top of Windshield inside the Vehicle. Yes - inside the vehicle on Center Top of Windshield.
There is a Self Adhesive tape which needs to be peeled off and then face the adhesive side on the windshield to paste it. Important to note that no additional tape or adhesive need to be used, else will damage the FASTag
Recharge FASTag: Then you can recharge this Fast Tag easily online any time through Credit Card, InternetBanking so as to load with prepaid balance. As part of First year offer - Digital Payment done through FASTag on all National Highway Toll Payment will get 2.5% Cashback
Validity: The Fast Tag is valid for 5 years from the date of purchase, post which renewal has to be done as per applicable slab at the renewal time.
Whenever the car passes in toll – an SMS is sent to customer informing debit amount and balance of his Fast Tag account. So it Easy - Convenient and saves times and money to get FASTag in your car.
Fastag Q&A
Q. What Happens on Toll Fee when you want Return Journey Ticket as Return Journey within 24 Hours generally cost lesser
A. The first time you cross Toll will debit you equivalent to One way Toll Charges. But if you return within 24 Hours then system will automatically calculate in Return journey charges as applicable and adjust in toll fees on return so that lesser toll will be debited to account
Thus, even if you crossing within 24 hours then total toll charges will be same as Return Journey charges within 24 hour
Q. What Happens on Toll Gate if any Technical Problem in RFID Scanning Device
A. No Charges will be deducted and even no Cash needs to be paid.
Q. Is FASTag RFID Secure
A. Yes, as payment debited only through approved RFID Scanner of NETC (National Electronic Toll Collection)
Q. What Happen when Car Sold
A. The Balance can be transferred to new FASTag
Q. What Happen if FASTag became unusable or Windshield Broken
A. You need to apply for New FASTag and pay Issuance fees only. The Old Balance can be transferred to new FASTag
Q. Any Higher Fees Deducted on FASTag
A. Call up Issuing Bank Customer Care with Details


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SNC-Lavalin Group Inc. said it's not for sale after the Financial Post reported that at least two rivals had approached Canada's largest engineering and construction company to discuss a takeover.
Spain's Actividades de Construccion y Servicios SA, one of two possible suitors cited by the Financial Post, said it wasn't interested in SNC. The other company named by the newspaper, WorleyParsons Ltd. of Australia, didn't immediately respond to an e-mail message sent after regular business hours there.
"While SNC-Lavalin does not comment on rumors, I can say that the company is not for sale," spokesman Louis-Antoine Paquin said in an e-mail. "SNC-Lavalin is not engaged in any discussions of this nature with any companies."
ACS isn't interested in SNC-Lavalin, Juan Jose Diaz Clavel, a Madrid-based spokesman for the company, said by telephone.
SNC pared early gains in Toronto trading after the company's comments. The stock gained 1.7 percent to C$46.39 at 11:24 a.m. in Toronto after touching C$47.40, the highest price in intraday trading since Nov. 4.
"We expect any process to take some time as bidders have to sort through a number of unique issues surrounding the company," Chris Murray, an AltaCorp Capital analyst, said in a note to clients. "However we do believe a sale could create value for shareholders."
SNC slumped 13 percent in the 12 months ended Tuesday as the global decline in oil prices weighs on a company already grappling with a federal corruption investigation involving the predecessor of Chief Executive Officer Robert Card. Montreal- based SNC bought oil-services provider Kentz Corp. last year.
Sytchev rates the stock as buy, the equivalent of Murray's outperform recommendation.


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