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After a spectacular January, the second month of 2019 also turned out positive for Wall Street with SPDR S&P 500 ETF SPY, SPDR Dow Jones Industrial Average ETF (DIA - Free Report) and Invesco QQQ ETF QQQ adding about 3.4%, 4% and 3.7%, respectively. Overall, the broader market was charged up and iShares Core S&P Total US Stock Mkt ETF (ITOT - Free Report) gained about 6.1% past month (as of Feb 27, 2019).
In fact, February's performance positioned the S&P 500 for its best year-to-date performance in more than three decades, per financial times. The S&P 500 has recoiled sharply this year from the Christmas slump and is now less than 5% away from its record high five months ago as indicated by financial times.
Against this backdrop, let's delve a little deeper into the key ETF events of February that helped Wall Street maintain its 2019 mojo.
Dovish Fed
The Fed minutes from the Jan 29-30 meeting confirms the patient view of the central bank toward future rates hike. The Fed started offering a dovish tone from the start of this year, which is one of key reasons for the market rally. A dovish Fed has kept Invesco DB US Dollar Bullish (UUP) (up 0.6% past month) at a subdued level.
U.S.-China Trade Relation: Peaks & Valleys
Apparently, the month was all about U.S.-China trade optimism. On Feb 25, President Donald Trump even announced a delay in the increase of tariffs to 25% on about $200 billion worth of Chinese goods, citing "substantial progress" in trade talks with Beijing (read: Top Performing ETF Areas of February).
With this, the year-long trade dispute between the world's biggest economies was thought to be reaching a conclusion. However, there was skepticism too in the U.S.-China trade relation. At month-end, U.S. trade representative Robert Lighthizer told Congress that the disagreement between both countries "was too serious to be solved by promises by China to buy more US products."
Whatever the case, China ETFs were clear winners in the month. Global X MSCI China Information Tech ETF CHIK, VanEck Vectors ChinaAMC SME-ChiNext ETF (CNXT - Free Report) and VanEck Vectors ChinaAMC CSI 300 ETF PEK returned in the range of 15% to 20%.
Zero-Fee ETF to Hit Market?
In late February, Social Finance Inc., an online lender also known as SoFi, made headlines by proposing two ETFs that will waive off managed fees for at least the first year of operation. Not only this, renowned issuer Vanguard also cut fees of the 10 key ETFs like Vanguard FTSE Emerging Markets ETF (VWO - Free Report) as part of the ongoing fee war trend (read: Zero-Fee ETFs to Hit the Market Finally?).
M&A Holds Up Biotech Sector
A solid merger-and-acquisition momentum has been instrumental in the biotech rally this year. February was no exception as Swiss pharma giant Roche Holdings (RHHBY - Free Report) announced the acquisition of the U.S.-based gene therapy company Spark Therapeutics ONCE for $4.8 billion (read: Biotech ETFs Jump on Roche-Spark Deal).
Principal Healthcare Innovators Index ETF (BTEC - Free Report) , ALPS Medical Breakthroughs ETF (SBIO - Free Report) and Virtus LifeSci Biotech Products ETF BBP are some of the winners in the month, having gained around 10% each.
Marijuana Maintains its Mojo
Pot stocks are on a tear this year on positive industry-specific news and renewed risk appetite. February's key tailwind in the marijuana market was Canadian cannabis firm Tilray Inc.'s TLRY announcement of acquisition of the world's largest hemp food maker Manitoba Harvest for $318 million. Growing efforts of inducing cannabis in food, beverage, tobacco and beauty products explain the 15% one-month gains in ETFMG Alternative Harvest ETF MJ (read: Tilray's Deal to Buy Hemp Food Maker Bolsters Marijuana ETF).
Busy U.S. IPO Market
Just as the government reopened, the U.S. IPO market charged up in February. In late February, Up Fintech and NASH biotech Genfit came up with IPO filings. Cardiovascular disease device maker ShockWave Medical, Diamondback midstream services unit Rattler Midstream LP, and NASH biotech Cirius Therapeutics are also on their way for a March IPO. Renaissance IPO ETF (IPO - Free Report) was up 14% in the past month (read: Will IPO ETFs Sizzle in 2019?).
Brexit Could Be Delayed
Amid huge internal differences, the UK parliament is now likely to decide between "no deal" and delay in Brexit. If the no-deal option is voted down, the Commons in the U.K. will have a chance to request prime minister May for an extension to Article 50, postponing Brexit by a few months, per an article published on CNN. However, France and Spain already signed their disapproval to a likely last-minute request for a two-month extension of the Brexit (read: Brexit Delay in the Cards? Europe ETFs to Rally).
If Brexit delays, several Europe-related ETFs like Invesco CurrencyShares British Pound Sterling (FXB - Free Report) , First Trust Europe Alphadex Fund (FEP - Free Report) , Europe Smallcap Dividend Wisdomtree (DFE - Free Report) and Europe Financials iShares MSCI ETF (EUFN - Free Report) should go higher.
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Global Integrated Shipping Information System (GISIS)
Annual IOEO Summary Report for 2019
IMO Financial Statements
Financial Regulations and Financial Rules
IMO Code of Ethics
IMO News Magazine
Lessons Learned from Marine Casualties
The Global initiative for West, Central and Southern Africa, GIWACAF works alongside 22 partner countries in Africa to strengthen their national capacities for preparedness and response to oil spills. In order to continue to improve the level of preparedness during the pandemic, GIWACAF has launched a series of webinar to keep providing capacity-building activities and best practices to its stakeholders and beyond. The webinars began in June and will run monthly through to late automn. more...
IMO remains committed to reducing GHG emissions from ships, even though the COVID-19 pandemic has led to postponements of important marine environment meetings and forced the maritime community to focus on other pressing issues, such as crew changes. In order to keep up the momentum on the implementation of the Initial IMO Strategy on reduction of GHG emissions from ships, IMO is holding an informal (virtual) preliminary discussion session on short-term measures for reducing GHG emissions from ships (6-10 July). more...
Governments have the power to solve a growing humanitarian crisis and must take action to bring seafarers home and allow their relief crews to join ships. "Get our hero seafarers home" was the plea from panelists during a webinar (26 June) hosted by IMO on the occasion of the Day of the Seafarer. IMO, the International Chamber of Shipping (ICS) and the International Transport Workers Federation (ITF) urged countries to implement protocols on safe crew change developed by the maritime industry and circulated by IMO. more...
Mr. Kitack Lim

subset: commoncrawl


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Practicality is the name of the game when creating a family transporter, and this Dodge Journey has it in spades. This 2014 Dodge Journey is for sale today in Sudbury.
There's no better crossover to take you on an adventure than this Dodge Journey. It's the ultimate combination of form and function, a rare blend of versatility, performance, and comfort. With loads of technology, there's entertainment for everyone. It's time to go - your Journey awaits. This SUV has 76223 kms. It's gray in colour and is completely accident free based on the CarProof Report. It has an automatic transmission and is powered by a 2.4L I4 16V MPFI DOHC engine. It may have some remaining factory warranty, please check with dealer for details.
To view the original window sticker for this vehicle view this http://www.chrysler.com/hostd/windowsticker/getWindowStickerPdf.do?vin=3C4PDCAB0ET176447.
To apply right now for financing use this link http://www.sudburyhyundai.net/finance/credit-application
Buy this vehicle now for the lowest bi-weekly payment of $98.53 with $0 down for 72 months @ 5.99% APR O.A.C. ( Plus applicable taxes - Plus applicable fees / Total cost of borrowing $2471 / Total Obligation of $15370 ). See dealer for details.
Come by and check out our fleet of 40+ used cars and trucks and 110+ new cars and trucks for sale in Sudbury. o~o


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Ain't no power in the 'verse can stop this wax!
Scent: Spearmint and lemongrass
Official Directions: Remove melt from package and place a few cubes in a device approved for use with wax melts. Engage heat. Inhale. Smile. Emit happy sighs. Only for use by attentive adults in a well ventilated area, away from combustible materials. Not for children, pets, or mystical creatures. Please sniff responsibly!


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I've started a yahoo league and need up to 12 managers, as it is a 16-team league with 4 managers so far. The rules are in place, but will not be finalized until the league votes collectively. Large rosters, and competitive, no entry fee. Been playing Fantasy Hockey since '16, and I have commissioner experience. Draft is November 30th, but will change as managers join. Please reply if you will be an active manager.
Last edited by Rajin; November 24, 2019 at 1:14 PM.


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As a social networking site, Facebook marketing is rapidly becoming one of the top businesses in the world. If you want to make a success out of your business then you should learn the skills to attract more people to your profile and to extend your network. But even if you want to use Facebook marketing to your advantage, you have to keep in mind that there are a lot of competitors using this social networking site and they are also trying to make their profiles more interesting than your profile. So, here are some tips that will help you get the most out of Facebook marketing: Visit here for more information Curt Maly – The BELT Method 2020
Stay active on your page – Engaging in conversations with your friends can help you build a community. Keep in mind that you do not have to post your information all the time. You can also send out useful messages to your network of friends in the morning and at night. Remember that if you can keep your network interested, it will be easier for you to convert them into paying customers.
Expand your reach – Don't just try to make a long term goal for your account. As much as possible, you should always be sharing good and informative content with your friends and followers. This will help you get a lot of new customers. So, make sure that you share valuable information that will help people gain knowledge and experience. And also try to have interesting posts to make your network interested about what you are offering.
Use pay per click – Before you start marketing, you should know that there are a lot of websites that offer you advertisements or ads. It would be better if you use pay per click services to get a higher return from your campaign. You can find the right company to manage your account by looking up in reviews sites or forums.
Make use of bookmarking websites – To encourage more traffic to your company's website, you can make use of bookmarking websites. Just bookmark any articles, blogs, comments, or websites that can help boost your traffic. And, if you are just looking for a good blog, you can also bookmark the blog of your company.
Don't hesitate to ask for help – Sometimes, there are things that you are unable to do alone. To help you get better results, you should be open to asking for help from other members of your network. Ask them to give you more content to be posted on your Facebook profile. Then, you can also ask for help when it comes to writing more content for your site.
Create social media – There are a lot of benefits that you can get from social media. You can ask your friends for help in starting a Facebook community and can make use of the social media to help you spread the word about your company. Your friends might also be able to provide you with some useful information on how to build a successful business.
These are some tips that you can use when you are trying to improve your Facebook marketing. Be sure that you will be able to grab the maximum benefits from this social networking site so that you can make a successful business.


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Omar Guzmán - Giróscopo download album
- Performer: Omar Guzmán
- Album: Giróscopo
- FLAC: 1969 mb | MP3: 1169 mb
- Style: Art Rock
- Rating: 4.3/5
- Votes: 121
- Format: WAV WMA MMF VQF DTS FLAC MIDI
Complete your Salvador Aguero Patino record collection. Discover Salvador Aguero Patino's full discography. Shop new and used Vinyl and CDs.
Booking details: Cat Music Booking & Concerts Madalina Simionescu: +. 744. 288 (Arabic Support).
Corazones is the 28th studio album by Omar Rodríguez-López as a solo artist, released on 29 July 2016. It is his second release in the 12 album series initiated by Ipecac Recordings. The song "Sea is Rising" made its first studio appearance on 2013's Unicorn Skeleton Mask, while the song was actually debuted instrumentally on the Omar Rodriguez Lopez Group 2010 tour. Running Away" was uploaded in advance as the album's single.
Check out Omar Rodríguez-López's gear and equipment including the Fender Mustang Electric Guitar, Ibanez AX120 Custom, and Ibanez Jet-King Omar Rodríguez-López Signature ORM-1. Used in Bosnian Rainbows on their first tour and their first album more. Used in Bosnian Rainbows on their first tour and their first album. Its a left handed 3/4 scale 60's Supro "super". Omar bought it because of its thick neck and because it his hand naturally falls where the lower notes were, which he was more interested in at at the time.
Omar Guzmán, studied Linguistics at Universidad Autónoma Metropolitana. Answered Apr 4, 2019. more)Loadin. hat popular music in the . overlaps with Mexico? Omar Guzmán, lives in Mexico. Answered Mar 25, 2019. Omar Guzmán, lives in Mexicali, Baja California, Mexico. Answered Mar 21, 2019. If Mexicans and Central Americans are in such dire need, why won't these States declare a "National Emergency" and we can help them there, not here? Omar Guzmán, I am one. Answered Feb 22, 2019.
Are you Omar Guzman-Quevedo? Register this Author. Register with ORCID iD. PUBLICATIONS 16. Omar Guzman-Quevedo. About publications (16) network. Publications by authors named "Omar Guzman-Quevedo". Are you Omar Guzman-Quevedo? Register this Author. Omar Guzmán-Quevedo Raquel Da Silva Aragão Georgina Pérez García Rhowena J B Matos André de Sa Braga Oliveira Raul Manhães de Castro Francisco Bolaños-Jiménez. PLoS One 2013 9;8(9):e74990.
Omar Coria Fashion Photographer. MODELSOmar CoriaJune 01, 2019Débora, Omar Coria, Brazilian model, Mexico City. MODELSOmar CoriaApril 25, 2019Ana Pau, Mexican model, Omar Coria, Mexico City. MODELSOmar CoriaApril 10, 2019russian model, Omar Coria, Mexico City, Vika Radchenko.
Never miss another show from Omar Guzman.
Tracklist Hide Credits
Drums – Carlos Macías Orchestra – Filarmónica De La Ciudad De México*Percussion – Arturo Guzmán Piano [Steinway], Glockenspiel, Electric Piano [Fender Rhodes], Synthesizer – Omar Guzman
Electric Bass – Jorge RosellGuitar – Marco A. Morel*Synthesizer – Omar Guzman
Drums – Salvador Aguero PatinoDrums, Percussion – Arturo Guzmán Marimba – Salvador Aguero SalazarOboe, English Horn – Roberto KolbPiano [Yamaha C3], Synthesizer – Omar GuzmanSoprano Saxophone – Alejandro Campos
|Bajo Las Nubes (Ballet)
Synthesizer – Omar Guzman
|Bajo Las Nubes
|Casi Al Amanecer
Piano [Kurzwell] – Omar Guzman
- Mastered By – Juan Switalski
- Producer – Omar Guzman
- Text By – Juan Arturo Brennan
NotesTrack 1 composed on 1978, recorded on December 1982
Track 2 composed on 1994
Tracks 3 to 5 composed on 1981, recorded on March 1983
Tracks 6 to 10 and track 11 composed on 1997
Barcode and Other Identifiers
- Barcode: 7501905300095


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Parks also learned that those over-the-top homes spend more on video in general than other homes – about $67 per month on video, versus $40 on average for all U.S broadband homes. (That figure does not include pay-TV services, though most over-the-top users have pay-TV service).
Services that integrate both transactional and subscription over-the-top video are tapping into this consumer mindset, Parks added. Amazon Prime, for instance, offers a subscription service as well as videos for purchase. About two-thirds of Amazon Prime Instant Video subscribers also use Amazon transactional service, and the amount they spend on rented and purchased videos is rising, Parks said.
Many homes are watching such over-the-top services not only on TVs, but also on mobile devices. The Diffusion Group found that among adult broadband consumers, 15% of tablet users and 14% of smartphone users will occasionally connect their mobile devices to their TV to watch video on the big screen. This is still an early adopter behavior, but it could become an "early mainstream behavior" in the next few years, TDG said. This type of convergence makes sense. Mobile and tablet videos now account for more than 10% of all online video plays, Ooayala has said.


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In the run up to your big day, it's the perfect way to stay informed so that you can make all the best choices for your wedding.
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When it's time for you look for local businesses to help you with your wedding, take a look at our advertisements below. Most will have links to their own websites. These advertisements are updated regularly so please revisit often and mention County Wedding Magazines when making any enquiries.


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As someone who has been working from home for years, I want to share realistic tips that have helped me and my clients find a work from home routine that works. If you are overwhelmed by creating a new routine or can't seem to make habits stick, we are here to help!
We don't want you to feel overwhelmed creating a new routine. We are all at different places in this process and health is a journey, not a destination. We recommend making 2-3 SMART goals to focus on during the week. SMART goals means the goal is specific, measurable, attainable, relevant and time based. By making SMART goals, you can slowly but surely create lasting habits.
When you are spending more time at home, you have to have a realistic plan for your day and build routine. Be proactive in your new work from home environment. There is naturally more flexibility working from home, you will find yourself preparing more meals, eating more at home, and moving less. The time is now to make time for your health and wellness.
Our dietitians help you create healthy routines for your lifestyle in the most realistic way. Our objective is not to overhaul your entire lifestyle, but rather help you make small tweaks to build healthy and lasting habits. We keep you accountable to your goals and provide you with personalized, expert recommendations. Here are our top habits for staying healthy while working from home:
1. Be Well Hydrated
Did you know your body is 70% water and your brain is 75% water? Hydration is essential for basic body functions, cognitive function, digestion, performance and recovery.
How much water should you be drinking during the day? Aim to drink .5 – 1 ounce of water per pound of your body weight. For example, if you weigh 180 lbs, drink 90-180oz (3-6 Liters) water daily. This may seem like a lot of water, but water is essential for life. The best way to stay well hydrated is first knowing how much water you should be drinking each day.
Once you know how much water you should be drinking, make a daily goal to meet this minimum level of hydration. There are many tactics to successfully drink more water – there is no one size fits all. Start small and be realistic. If you usually drink 2 bottles on auto pilot, try to shoot for 3-4 bottles of water. Tactics to up your hydration include: drinking water with meals, drinking water with snacks, drinking water before other drinks like coffee and setting 1-2 time based goals to drink "x" oz water before "x" time.
Do you get bored drinking plain water? Besides plain ole H20, other hydrating drinks include sparkling water, unsweetened teas, infused water, unsweetened and non-artificially sweetened drinks. To make infused water, add fresh fruits to water to make a refreshing and hydrating drink. If you're looking to add sweetness, try combinations of infused water with strawberries, pineapple and watermelon. Create an infused pitcher or bottles of water to easily pour and drink. For sparkling water, there are many minimally processed options like La Croix, Waterloo, Topo Chico, Spindrift … all surprisingly delicious! Sparkling water is like treating yourself to a refreshing can of soda during lunch or you can pop one to enjoy after a long day.
Staying well hydrated is essential for optimizing your health and day to day functions. If you need accountability to hit your goals, we are here to help you with a personalized strategy and plan to stay well hydrated.
2. Hit Pause Before Mindlessly Snacking
You need a break from work so you find yourself in the kitchen. Mindlessly snacking is when you wander into the kitchen because you're bored or tired and blankly stare at the open refrigerator. What you really need is a break from working, but instead you are eating to fill the time.
Stop and hit pause. Are you really hungry? Or are you really just needing a break? If you are hungry, it's always appropriate to eat. You may find it helpful to practice hitting pause to check in on your hunger level before snacking. You may notice you are opportunistically snacking or using snacking to distract yourself from getting back to work. Mindless snacking is a short sighted way to fill your time. It's also an easy bad habit to fall into. How often, if ever, do you really feel better after over snacking?
Instead of breaking for a snack, break for a walk, take a stretch, do house work, meal or snack prep for later in the day (wash and cut), grab a glass of water or dance it out listening to a few favorite songs. Want help coming up with a plan to become a more mindful eater? Schedule a call with our dietitians to see how we can help you out.
3. Prioritize Meal and Snack Times
On a busy day, it's easy to skip meals and snacks. Next thing you know you're ravenously hungry, grazing from snack to snack and overdoing portions. This cycle of eating is completely normal and the good news, it's avoidable if you practice more intentional eating. You may be self-sabotaging by skipping meals and snacks. Instead of drinking 2-3 Cups of coffee, skipping breakfast and eating bird food for lunch, have a plan for what to eat as a balanced breakfast, balanced lunch and balanced snacks.
Do you find it hard to take a break and make time for a healthy snack? Try setting calendar reminders as alerts to remind yourself to eat regularly during the day. Setting reminders may seem like overkill, but give it a try and thank me later! You can benefit from ongoing reminders to eat lunch and to eat a mid-afternoon snack. Honor the reminder to take care of yourself so you can think clearly and perform optimally.
While there are benefits to taking undistracted meals and snacks, just focus on setting the reminders to get started. A general recommendation is 30-45 minutes for lunch and 5-10 minutes for snacks.
Unsure what to eat and when to eat? We are here to help break it down for you in an initial session.
4. Time Block Movement
Do you find yourself saying, I will workout tonight or go for a walk at the end of the day … but never end up finding the time? Make the time in your work calendar to stop and break for movement.
Most of us think of exercise in 1 hour increments. If it's hard for you to stop for 60 minutes of uninterrupted movement, begin to think of movement in 15-20 minute time blocks. It's much more manageable to think in smaller time blocks and you may be more likely to workout because 20 minutes feels more realistic. Throughout your work day, take a few 15 minute walks, 20 minutes of strength training or 20 minutes of stretching or yoga.
Use your work calendar to time block off 2-3 blocks to get up from working and get moving. If you have a consistent schedule, set a repeating reminder. If your days vary, look a few days ahead to prematurely block off time in your schedule. Make the time and honor the blocks you set! Taking 15-20 minute breaks can improve performance and leave us feeling more focused when we get back on task.
If you need more accountability to your workout and movement routine, we are here to help you stay on track with your routine.
5. Have a Meal and Snack Plan
The term meal plan gets a bad wrap. When I think of a "meal plan", what comes to mind is a rigid, unpersonalized and unrealistic plan that you can probably do for 1-3 days. We help clients with realistic meal and snack plans. Some of our clients love cooking, others loathe it. Surprisingly, you don't always have to cook to be prepared with meals and snacks.
There are many ways to better plan for meals and snacks, but the most common methods are traditional meal prep, modified meal prep and assembly meal prep. Traditional meal prep is home cooking. As a home cook, we encourage taking shortcuts because let's be honest no one has time to roast and peel beets. Modified meal prep is using shortcuts, batch prepping for multiple meals during the week and using convenience foods to streamline meal prep. Have you ever used a roasted chicken or leftover beans in a few different ways? This is how you modified meal prep. Finally, assembly meal prep is loved by college students, busy moms and bachelors. Grocery stores have lots of ready made, pre-cooked and healthy packaged foods. A quick weeknight assembly meal plan can include rotisserie chicken with frozen rice and bagged salad or sandwiches with a piece of fruit.
Having a simple meal and snack plan will help you stay on track while eating at home. Nutrition is not black and white, so we very much expect our clients to use their meal and snack plans as a guide for the week. Having a plan for 2-3 choices at meals makes grocery shopping easier and ensures you always have a few options during the week to fall back on.
Want a simple meal plan fit for your preferences and cooking abilities? Schedule a free call with one of our dietitians to get started with food coaching.
Do you need to create a healthy work at home routine? We are here to support you in creating a lasting, healthy routine. Your dietitian will provide recommendations fit for your work schedule, preferences and lifestyle. Schedule a complimentary call to get your questions answered about our nutrition services and make sure working together is a good fit.
5 Healthy Habits For Working From Home
Mar 23, 2020 | Ask the Nutritionist, Ideas for You | 0 comments


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Historical Mortgage Rates: Averages and Trends. – ValuePenguin – Today, current mortgage rates remain at historic lows around 4% – with over 63% of homeowners with mortgages paying interest rates between 3% and 4.9%, according to the Census Bureau. As of June 2017, interest rates for new 30-year mortgages were as low as 3.89%.
Fha Upfront Mip Calculation At NerdWallet, we adhere to strict standards of. from periodic delinquencies or a collection could still qualify, however. FHA loans require an Upfront Mortgage Insurance Premium. This amount is.
See how Australian interest rates have fluctuated over time and compare today's rates. On this page you can find the average standard variable home loan interest rate from 1959 until the present.
Historical Interest Rates Australia – Australian Home Loans – Home Loan F05 Indicator Lending Rates The graph below shows the historical f05 indicator lending rates for home loans, which appear to me to be about 1.8 to 2.5% higher than the Reserve Bank of Australia's official cash interest rate.
Best Month To List A House When's the Best Time to List a House? – Realtor McLean VA – To calculate the best time to list, we begin by grouping homes by the month they were first listed, then calculate how much those homes tend to sell for relative to their Zestimate, Zillow's estimated value placed on roughly 100 million homes nationwide.
View daily mortgage and refinance interest rates for a variety of mortgage. Use our compare home mortgage loans calculator for rates customized to your.
Why Mortgage Rates Once Reached a Sky-high 18.5% – Imagine paying over 18% interest on a 30-year fixed mortgage. It's almost unthinkable. But that was the reality for home buyers in October 1981 – a year when the average rate was almost 17%.
Monthly Interest Rate Survey | Federal Housing Finance Agency – Update on the Discontinuation of fhfa's monthly interest rate survey (mirs) On May 29, 2019, FHFA published its final Monthly Interest Rate Survey (MIRS),
Home Mortgage Rates Historical Mortgage Rates by Month – 1986 to 2016 HSH's National Monthly Mortgage Statistics: 1986 to 2016 HSH's Fixed-Rate Mortgage Indicator (FRMI) averages 30-year mortgages of all sizes, including conforming, expanded conforming, and jumbo.
Realtors Report Latest Local Home Sales Figures – Time on market inched up from 18 days in May to 19 days in June. It took a median number of 15 days to sell a home in June.
Paying care home fees: what everyone needs to know – If you really have to sell your home to fund your care, you need to maximise the resulting capital by either choosing a.
Chase Home Equity Loan Fixed Rates Fha Mortgage Refinance Rates 2019 FHA Loan Rates – How to Find Better Interest Rates. – updated january 2018. fha streamline is one of the most popular mortgage refinance programs in the last couple of years. If you are interested in FHA streamline mortgage refinance, it is important that you know what the current rates are – because they change frequently.Home Equity Loan: As of March 23, 2019, the fixed Annual Percentage Rate (APR) of 4.89% is available for 10-year second position home equity installment loans $50,000 to $250,000 with loan-to-value (LTV) of 70% or less. Rates may vary based on LTV, credit scores, or other loan amount.
Causes of the United States housing bubble – Wikipedia – Observers and analysts have attributed the reasons for the 2001-2006 housing bubble and its 2007-10 collapse in the United States to "everyone from home buyers to Wall Street, mortgage brokers to Alan Greenspan". Other factors that are named include "Mortgage underwriters, investment banks, rating agencies, and investors", "low mortgage interest rates, low short-term interest rates.
As of July 17, 2019, mortgage rates for 30-year fixed mortgages fell over the past week, with the rate borrowers were quoted on Zillow at 3.82%, down 11 basis.


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One of the best things video games can do is bring people together. Multiplayer has been around for decades, and with a general shift toward online multiplayer being the only way to play with others, local multiplayer and party games have been declining. Despite this, some of the greatest video games created were made specifically with local multiplayer in mind. Recently Nintendo seems to be the only publisher making games to fit in this genre, but there have been dozens of games released over the past years that exemplify the party genre. Here is my list of the ten greatest party games ever! Read the rest of this entry »
Tag Archives: New Super Mario Bros. U
Sunday Roundup: 11/24/13 – The Wii U Edition
I bought a Wii U!!
And with some pretty great deals surrounding it: I was able to score the Legend of Zelda Special Edition system for nearly $75 off, as well as snag some cheap, brand new games!
And what could make this week even more awesome? Getting a trio of Saturn games off eBay, of course!! Winners all around!! More exclamation points!!! Read the rest of this entry »


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What are the Patterns of a Conservation Economy?
U.S Coast Guard Housing in Astoria, OR
The U.S. Coast Guard received an award for developing innovative and attractive family housing in Astoria. Building on a 45-acre site within the city limits, the development team surveyed Astoria's neighborhood characteristics and worked with the city and its residents to ensure it would be compatible with Astoria's existing community. The development emphasizes the connection between homes, schools, commercial services, and open spaces in the area.
Orenco Station in Hillsboro, OR
With a site designated as a town center in Metro's region 2040 plan, the developers of Orenco Station set out to realize the vision of living and workng in wakling distrance of transit, and Orenco Station is already demonstrating that mixed-use development near light rail can work — and sell. The plan was created to take advantage of the light rail's proximity as well as to support transit by providing a higher density of residential and commercial uses within walking distance. The project features a mix of housing types, parks and open spaces, a traditional neighborhood main street, and an adjacent community shopping center. The design includes pleasant sidewalks, narrow tree-lined streets and through connections to surrounding streets and businesses. And all of this is next to some of the area's largest high-tech employers.
Fairview Village in Portland, OR
Fairview Village is gaining National attention for its unique approach to neighborhood design. It is a mix of houses, rowhouses, & apartments built among retail, office, and other civic amenities. In short, a town designed the old-fashioned way - with all the comfort and community feel of a small town, and all one's daily necessities just a short stroll away. The homes are designed with timeless charm and grace and built with traditional craftsmanship — but using contemporary floorplans and amenities. These are not tract homes...we have an endless variety in the Village. We believe they are simply...the best-built homes in the Portland marketplace.
Livable Oregon
Partners for Livable Communities
Calthorpe, Peter. The Next American Metropolis: Ecology, Community, and the American Dream. Princeton Architectural Press. Princeton, NJ. 1993.
Corbett, Judy and Michael Corbett. Designing Sustainable Communities: Learning from Village Homes. Island Press. Washtington, DC. 2000.
« Previous Pattern | Next Pattern »
A Conservation Economy
Social Capital
Fundamental Needs
Subsistence Rights
Shelter For All
Access To Knowledge
Social Equity
Cultural Diversity
Cultural Preservation
Sense Of Place
Beauty And Play
Just Transitions
Civic Society
Natural Capital
Ecological Land-Use
Connected Wildlands
Core Reserves
Wildlife Corridors
Buffer Zones
Productive Rural Areas
Sustainable Agriculture
Sustainable Forestry
Sustainable Fisheries
Compact Towns And Cities
Human-Scale Neighborhoods
Green Building
Transit Access
Ecological Infrastructure
Urban Growth Boundaries
Ecosystem Services
Watershed Services
Soil Services
Climate Services
Economic Capital
Household Economies
Green Business
Long-Term Profitability
Community Benefit
Green Procurement
Renewable Energy
Sustainable Materials Cycles
Resource Efficiency
Waste As Resource
Product As Service
Local Economies
Value-Added Production
Rural-Urban Linkages
Local Assets
Bioregional Economies
Fair Trade
True Cost Pricing
Product Labeling


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These extra large greetings cards are bold, cheerful & sure to make bird lovers chuckle. Bring a smile to your bird loving buddies, colleagues & loved ones with a message of thanks from this well meaning robin!
Cheeky Birds Thank You Card
- Extra large card! Measures 21 x 15cm
- Risograph print in red
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- Printed on 170gsm recycled yellow card
- Paired with a brown kraft envelope
- Packaged in a bio-degradable cellophane bag
- Posted in a sturdy cardboard envelope


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Introduction – Kirstie Alley's Hair Should Pass Abercrombie & Fitch Cool Test
Abercrombie & Fitch chief executive, Michael Jeffries, was a media target for the brand's message of only wanting cool kids coming through its doors. Beloved Dancing With The Stars star Kirstie Alley recently took to Twitter to slam Jeffries for the company's refusal to stock items in larger sizes. Kirstie Alley's hair should pass Abercrombie Fitch's cool test.
Not to mention Kirstie is amazingly cool in so many other ways.
Does Abercrombie & Fitch deserve the media blast they received after explaining why they only want the thin and the beautiful kids in their stores? Most experts believe they do. They also support Kirstie, who is definitely cool due to for her long luscious locks, willingness to share her weight battles with the world and her concern with the wrong message Abercromie is sending to young people.
Especially now in the era of bullying where kids are harassed over their body type, individual characteristics, race and gender. They're bullied for being different or not cool in any possible way.
Obviously the message sent my Abercrombie plays into bullying by promoting the ideal that only thin and beautiful people are cool.
Abercrombie & Fitch Refusing To Stock Larger Sizes
The media dust-up started with a May 3 Business Insider story about Abercrombie, unlike its prime competitors, refusing to stock clothes in XL and XXL. The story resurfaced comments made by Jeffries to Salon in 2006, in which he said his business was built on sex appeal and therefore "we want to market to cool, good-looking people. We don't market to anyone other than that."
The controversial CEO was also quoted as saying "In every school there are the cool and popular kids, and then there are the not-so-cool kids," he continued in the quote that went viral. "Candidly, we go after the cool kids. We go after the attractive all-American kid with a great attitude and a lot of friends. A lot of people don't belong [in our clothes], and they can't belong. Are we exclusionary? Absolutely."
Kirstie Alley Slammed Abercrombie & Fitch In Media
The outspoken actress took offense to the Abercrombie message, especially since she has publicly waged her own battles with her weight and understands the pain of body size discrimination.
As a result the actress slammed Abercrombie honcho Michael Jeffries on Twitter, taking personal shots at the chief exec.
Kirstie tweeted "Dear CEO of Abercrombie & Fitch…you are not cute and your head is HUGE. You need to stop wearing A&F clothing…just not attractive enough," . She also tweeted "Dear Abercrombie & Fitch CEO, If I ever meet you at a party, don't stand close to me. Your veneers are blinding & could take down a G6 [airplane]." Finally Kirstie posted "Dear CEO of Abercrombie & Fitch, arent you the same douche frog that ok'd THONGS for six y/o girls??"
To underline her anger at the discriminatory messages of A&F the actress went on "Entertainment Tonight," to encourage folks of all sizes to stop shopping at A&F. "I've got two kids in that [target] bracket, but they will never walk in those doors because of his view of people — forget women, his view of just people," she explained.
The Abercrombie CEO finally addressed the issue Thursday in a statement which fell short of an actual apology. Jeffries said he regretted his "choice of words was interpreted in a manner that has caused offense," stating that the "7-year-old, resurrected quote (from Salon) has been taken out of context."
A&F "targets its marketing at a particular segment of customers," the CEO said, adding that A&F was opposed to discrimination and bullying based on "race, gender, body type or other individual characteristics."
Summary – Kirstie Alley Wins In A&F Dust-up
The result of all this media dust-up? Kirstie Alley is more respected and appreciated than ever, but the A&F retailer's reputation among 18- to 34-year-olds has tanked in the last two weeks according to Business Insider.
In other news, the media reported that an unnamed man was handing out Abercrombie clothes on skid row in bid to shame the brand for their messages of discrimination against those deemed uncool.
Meanwhile, Kirstie Alley's coolness scores continue to skyrocket. Not only does she have amazing hair, she's maintained her significant weight loss, launched a product to help others struggling with weight and has a new TV series for 2013.
Kirstie has beautiful hair and is cool in so many ways that A&F should hire her to rebrand. After all the damage their body discrimination message has caused they're going to need a gorgeous celebrity spokesperson to get them back on track.


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Abstract. Fifty years after his death, Harold Innis remains one of the most widely cited but least understood of communication theorists. This is particularly true in. PROFESSOR INNIS has written a pioneering book and made a serious contrib nology, we can discover the specific "bias of communication" in each perio. Download Citation on ResearchGate | Harold Innis and "the bias of communication | Fifty years after his death, Harold Innis remains one of the most widely cited.
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Peter rated it it was hqrold Oct 24, Knowledge passed down orally depends on a lineage of transmission, often associated with ancestors, and ratified by human contact.
Harold Innis' bias of communications – a starting point, not a foundation
Innis's The Bias of Communication has played a major part in reshaping our understanding of history, communication, and media theory.
Jan 28, Szplug rated it really liked it Shelves: The first model is militaristic and concerned with the conquest of space.
Jun 17, George Walker rated it really liked it. As Canadian scholar Arthur Kroker writes, "Innis's political lesson was clear: Innis cojmunication outlined his ideas in The Fur Trade in Canada Innis considers political and economic forces in the context of social change and the role of communication in the creation of both ancient and modern empires. Characteristically, Innis summarizes the far-reaching implications of the new medium of paper in a single paragraph that starts with the Middle Ages and ends with the modern Communiication States:.
One of Harold Innis's primary contributions to the field of communications was to apply the dimensions of time and space to various media.
Harold Innis's communications theories – Wikipedia
According to its characteristics [a medium of communication] may be better suited to transportation, or to the pf of knowledge over time than over space, particularly if the medium is heavy and durable and not suited to transportation, or to the dissemination of knowledge over space than over time, particularly if the medium is light and easily transported. Innis believed that the overwhelming spatial bias of modern media was heightened in the United States by the development of powerful military technologies, including atomic weapons.
Innis devoted the remainder of his life to fleshing out these ideas, and toward comumnication end he began to explore the biases embedded in staples-driven communications systems. According to this view, certain social forms and situations encourage the development of new media; injis media, operating within existing situations, react back on society to produce a new cycle of change.
The development of "mechanized" communications media such as mass-circulation newspapers had shifted the balance decisively in favour of space and power, over time, continuity and knowledge. Comparatively, the media that have supported the military conquering of space have been lighter, so that the constraints of long distances could be lessened. Ted Turner buys RKO! He looked at media that led to the growth of an empire; those that sustained it during its periods of success, and then, the communications changes that hastened an empire's collapse.
The Laurentian paradigm dominated Canadian history and social science from the s to the early s. This contributes to an understanding of the timelessness of economic phenomena — like "the business cycle is as old as the Nile River". Apr 18, Kevin rated it really liked it.
Nov 10, Guy rated it it was amazing Shelves: MM rated it liked it Aug 14, Those who control knowledge have the power to define reality. Power was vested therefore, in a scribal and literate, religious elite.
The Bias of Communication by Harold A. Innis
Paper is such a medium; it is readily transported, but has a relatively short lifespan. Tom Dean rated it really liked it Sep 26, If you find the book slowing down, jump to the final chapter, "A Critical Review" for an ultimate synthesis of Innis's ideas — which were completely groundbreaking and paradigm-shifting at the time of publication. For them memory is of crucial importance; they revere the wisdom of elders and favour concrete over abstract forms of thought.
The adaptability of the alphabet to large-scale machine industry became the basis of literacy, advertising and trade. After the war, Innis studied political economy at the University of Chicago where he did his Ph. Heyer writes that Empire and Communications received few reviews and they ranged from "lukewarm to negative".
This site uses cookies. Then, universities could muster the courage to attack the monopolies that always imperil civilization. See also, Heyer, pp. In writing, the tendency is to isolate an aspect of some matter and to direct steady attention upon that aspect.
What Innis experienced during the war contradicted popular beliefs at home that the Canadian identity was a pale reflection of British imperialism and deepened his nationalist outlook. A monopoly control of communication defeated attempts to construct empires. Roy rated it really liked it Dec 21, Innis argued that a balance between the spoken word and writing contributed to the flourishing of ancient Greece in the time of Plato.
Media that emphasize space are apt to be less durable and light in character such as papyrus and paper. Books by Harold A. The limitations of the Egyptian empire were in part a result of the inflexibility of religious institutions supported by a monopoly over a complex system of writing. As a young professor at the University of Toronto, Innis was concerned that Canadians were being deluged with American material, so he set about to remedy that ckmmunication.
His reflections appear in separate chapters in his book Empire and Communications along with additional chapters on the combined effects of parchment and paper in the Middle Agesand paper and the printing press in the development of modern societies.
However, if you can make it through the book — you'll vias deep insights into the way our modern communication system aka — The Internet functions and become more keen to the biases which result from its monopoly on space. Each medium has its bias, a bias which changes in relation to the significance of the others in the consciousness of cultures. The god of writing was closely related to the leading deities and reflected the power of the scribe over religion.
Leave a Reply Cancel reply Enter your comment here Plato conveyed his ideas by recording the conversations of Socrates. Place and placelessness E. Concentration on a medium of communication implies a bias in the cultural development of the civilization concerned either towards an emphasis on space and political organization or towards an emphasis on time and religious organization.
We can further bia our study of media by focusing on the monopolies of knowledge within any empire, and the potential for marginalized cultures to adopt new technologies in order to gain some leverage against more powerful nations.


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Members must:
Members not adhering to the above are subject to suspension of membership privileges up to and including expulsion from the club.
ALWAYS keep your finger off the trigger until ready to shoot (sights on target)
When holding a gun, rest your finger on the trigger guard or along the side of the gun. Until you are actually ready to fire, do not touch the trigger.
I don't believe people should to be able to own guns.
Barack Obama
(during conversation with economist and author John Lott Jr. at the University of Chicago Law School in the 1990s)


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At Cengage, we are harnessing the power of tech to build a future where all learners have the tools and confidence to achieve their goals. As a Cengage employee, you will blaze a new trail to transform the way people learn. Collaborating with the best of the best, you will feel challenged and inspired to do breakthrough work. With the support of our united team, there is no limit to what you can imagine, create and set in motion.
We set the bar higher by bringing our unique talents and point of view to the table every day. We are curious and comfortable with change and are willing to take risks to transform education. Most importantly, with everything we do, we put learning first.
The Web Accessibility Specialist is responsible for technical development support and promotion of Cengage's aspiration to create inclusive, accessible learning experiences, with a focus on web accessibility. The Web Accessibility Specialist serves as the Learning Center of Excellence's technical accessibility subject matter expert for web accessibility – providing consultation for the design, production, and modification of digital media for Cengage product and platform teams to promote compliance with WCAG 2.1 standards. This role is critical to identifying accessibility barriers in digital products and proposing solutions to overcome them.
The Web Accessibility Specialist plays a critical role in communicating clear and consistent messaging involving web accessibility to all stakeholders, implementing web accessibility processes and procedures, and helping implement accessibility best practice in platform and digital media development. The Web Accessibility Specialist will work closely with the Accessibility Manager to ensure product teams receive the training, ongoing development, and support required to design, produce, and deliver accessible digital products.
The Web Accessibility Specialist is an ambassador for Cengage's commitment to inclusivity and accessibility both inside and outside of Cengage. Working in partnership with peers at Cengage is required to ensure stakeholders are aware of accessibility legislation and best practices that impact accessible web development, the organization and its products/platforms, and customers.
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In today's episode of The Startup Chat, Steli and Hiten talk about affiliate programs and how to use it for your business when you want to acquire more customers.
Affiliate programs can be an effective way to get new customers and scale your startup. For it to be successful, it is important to know how to create a program that helps your customers and advocates do your marketing for you.
In this episode, Steli and Hiten talk about what an affiliate program is, why they don't work for some startups, why some programs have failed in the past and much more.
Time Stamped Show Notes:
00:00 About today's topic.
00:46 What are affiliate programs?
01:09 Why it's a channel that works really well.
01:20 A key metric that you can use to determine if this is for you.
01:53 A mistake startups who want to use this channel make.
02:12 An interesting thing about affiliate programs.
03:52 Two reasons why affiliate programs work.
04:04 What a referral program is.
05:03 The reason affiliate programs don't work.
05:59 Another reason why affiliate programs don't work.
07:35 Examples of affiliate programs gone wrong
3 Key Points:
If my product already has a high word of mouth, it's more likely an affiliate program will work for you.
When you sell to b2b companies, just offering them some amount of money might not work as well.
You having an affiliate program doesn't really scale your business if a bunch of these factors are not in place.
Steli Efti: Hey, everybody, this is Steli Efti.
Hiten Shah: And this is Hiten Shah. And today on The Startup Chat, we're going to talk about affiliate programs, and how to use it for your business when you want to acquire more customers. I'm going to shoot this first, real quick, and then we'll get into it, Steli, 'cause this is one of those more rapid-fire ones, because it's just a topic and we haven't talked about it, but it's a super-important one, because it's affiliate partners, referrals, there's this whole category of, somebody is bringing me leads and/or sales for my business and I'm giving them some kind of commission. That's essentially what an affiliate is. Right?
Steli Efti: Right. Right.
Hiten Shah: I love the idea of having affiliates, or even partners that are bringing you customers for a commission. I think it's one of the key channels that, especially in B to B and SaaS, that works really well. It also works really well in e-commerce, and for me it has everything to do with one key metric, if this is going to work for you. And it's going to sound crazy, but it's pretty standard, but the key metric that I actually go for is, if my product already has high word-of-mouth, it is more likely that an affiliate program, or a referral in partnerships are going to work really well.
Steli Efti: Yeah, that makes so much sense it hurts. But I'm still sure that a lot of people-
Hiten Shah: Yeah, exactly, because not every product has that.
Steli Efti: Yeah, and I'm sure a lot of the startups that are considering or have chosen ... Let's invest in affiliate programs or referral programs to fuel our growth, have never stepped back to ask this very simple question, "Hmm. Do we get any word of mouth right now? Are our customers or people who know about us talking about us at all?" It seems like a very fundamental first step to answer before you go, "Let's pay them money, or give them incentives to do it." But-
Hiten Shah: Exactly.
Steli Efti: ... But I'm still, I would be surprised if a lot of people thought about that first. So one thing, one interesting thing about affiliate programs is that, or referral programs, is that I do think,


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On Thursday, the European Commission launched a second call for applications for a further 20,000 travel passes to 18-year-old Europeans wanting to explore the EU.
To be eligible to apply for one of the 20,000 travel passes, applicants must be born between 2 July 2000 and 1 July 2001, as well as hold citizenship from one of the EU member states. Travel passes can be valid for as little as a day and as long as a month.
Further requirements state that the travel period in question must occur between 1 August 2019 and 31 January 2020. The DiscoverEU initiative should mainly take place by train, but the European Commission will make allowances for those living in remote areas or on islands.
The application form is simple, as candidates only need to fill out a quiz with five multiple choice questions on general knowledge about the European Union, EU initiatives aimed at young people, and the European Parliament elections.
The European Commission has also fixed a quota of travel passes for each member state based on its population compared to the total EU population.
In its launch year of 2018, the DiscoverEU programme provided 30,000 European teenagers with travel passes. The budget for 2019 lays at €16 million.
The programme allows DiscoverEU ambassadors to travel to multiple destinations, but limits their transport budget to €260. Those benefiting from travel passes should ensure their itinerary fits the budget.
The programme also asks beneficiaries to "report back on [their]travel experiences through social media tools like Instagram, Facebook or Twitter using #DiscoverEU." The website even suggests that DiscoverEU ambassadors "could even give a presentation at [their] school or local community," as well as win prizes by participating in the photo and video competition.


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I Know You Lied
by Lesley Sanderson
Pub Date
This title was previously available on NetGalley and is now archived.
Buy this Book on
Buy this Book on
Pub Date
Talking about this book? Be sure to tag it using #WhatWeHide #NetGalley
The news of her mother's death hits Nell as if she's been shot. The letter must be some kind of prank, but who could be so cruel? Because Nell's mother died nearly thirty years ago.
When Nell was just a tiny baby, her parents died in a car crash, leaving her to be raised by her devoted grandmother, Lilian. So when the lawyer's letter arrives, informing her of her mother Sarah's very recent death, it destroys everything Nell thought she knew. Her grandmother loved her, so why did she lie? And why did her mother abandon her?
Nell knows she can never recapture the years with her mother that were taken from her, and fears this will haunt her forever. Now she won't rest until she finds out why she was so cruelly deceived. But her family's past has been kept secret for a reason, and someone is desperate for it to stay that way. How much danger will Nell risk for the truth?
If you loved The Silent Patient, The Secret Mother, and The Wife Between Us, then this addictive thriller about dark family secrets and obsession will have you on the edge of your seat.
*Previously titled: What We Hide
A Note From the Publisher
Advance Praise
Readers love Lesley Sanderson
'Wow wow wow!!!!!! What a thriller this book is! One killer secret that will leave you holding your breath until the last page! This book has so much suspense that you can't help turning the pages faster and faster!! A definite must read!' Goodreads reviewer, 5 stars
'WOW what a read! Just give me a minute I need to catch my breath!… Right from the start I was hooked and I couldn't flip the pages on my Kindle fast enough to see how it was all going to unfold. Lesley has done a great job with this story and her writing embodies everything that makes a psychological thriller great.' Once Upon a Time Book Blog, 5 stars
'What an addictive read – I got sucked in from page one and then went on a roller coaster ride of a read. WOW. Just WOW. WOW. WOW.' NetGalley Reviewer, 5 stars
'A taut, fast-paced psychological thriller that pulls you in from the very first paragraph. I could not turn the pages quickly enough… An absolutely gripping novel, chock full of twists and turns, and it will keep you guessing until the final dramatic conclusion.' Goodreads Reviewer, 5 stars
'Wow! This book had me up late, flipping pages and needing to know everything and everyone that was involved…. Thrilling, chilling and absolutely unputdownable! Will be highly recommending!' Chapter Chatter Pub, 5 stars
'A great psychological thriller. A cracking opener of a first page makes you wonder if that happened or it was a dream… This had more twists and turns than Strictly on a Saturday night and the author is one clever, devious manipulator.' Melanie's Reads
'This was a chilling read which had me hooked from the first page… This was a suspenseful thriller of a read, filled with lots of lies and mistrust. Would definitely recommend!' Stardust Book Reviews
Available Editions


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%0 Journal Article %J Journal of Global Oncology %D 2018 %T Development, Evaluation, and Implementation of a Pan-African Cancer Research Network: Men of African Descent and Carcinoma of the Prostate %A Andrews, C %A Fortier, B %A Quintana, Y %A Timothy Rebbeck %A el.al. %X
Cancer of the prostate (CaP) is the leading cancer among men in sub-Saharan Africa (SSA). A substantial proportion of these men with CaP are diagnosed at late (usually incurable) stages, yet little is known about the etiology of CaP in SSA.
We established the Men of African Descent and Carcinoma of the Prostate Network, which includes seven SSA centers partnering with five US centers to study the genetics and epidemiology of CaP in SSA. We developed common data elements and instruments, regulatory infrastructure, and biosample collection, processing, and shipping protocols. We tested this infrastructure by collecting epidemiologic, medical record, and genomic data from a total of 311 patients with CaP and 218 matched controls recruited at the seven SSA centers. We extracted genomic DNA from whole blood, buffy coat, or buccal swabs from 265 participants and shipped it to the Center for Inherited Disease Research (Baltimore, MD) and the Centre for Proteomics and Genomics Research (Cape Town, South Africa), where genotypes were generated using the UK Biobank Axiom Array.
We used common instruments for data collection and entered data into the shared database. Double-entered data from pilot participants showed a 95% to 98% concordance rate, suggesting that data can be collected, entered, and stored with a high degree of accuracy. Genotypes were obtained from 95% of tested DNA samples (100% from blood-derived DNA samples) with high concordance across laboratories.
We provide approaches that can produce high-quality epidemiologic and genomic data in multicenter studies of cancer in SSA.
Full Text Available at ResearchGate
Health research in low- and middle-income countries can generate novel scientific knowledge and improve clinical care, fostering population health improvements to prevent premature death. Project management is a critical part of the success of this research, applying knowledge, skills, tools, and techniques to accomplish required goals. Here, we describe the development and implementation of tools to support a multifaceted study of prostate cancer in Africa, focusing on building strategic and operational capacity.
Applying a learning organizational framework, we developed and implemented a project management toolkit (PMT) that includes a management process flowchart, a cyclical center-specific schedule of activities, periodic reporting and communication, and center-specific monitoring and evaluation metrics.
The PMT was successfully deployed during year one of the project with effective component implementation occurring through periodic cycles of dissemination and feedback to local center project managers. A specific evaluation was conducted 1 year after study initiation to obtain enrollment data, evaluate individual quality control management plans, and undertake risk log assessments and follow-up. Pilot data obtained identified areas in which centers required mentoring, strengthening, and capacity development. Strategies were implemented to improve project goals and operational capacity through local problem solving, conducting quality control checks and following compliancy with study aims. Moving forward, centers will perform quarterly evaluations and initiate strengthening measures as required.
The PMT has fostered the development of both strategic and operational capacity across project centers. Investment in project management resources is essential to ensuring high-quality, impactful health research in low- and middle-income countries.
Adherence to antiretroviral therapy (ART) is paramount to successful long-term suppression of human immunodeficiency virus (HIV). For poorly adherent patients with HIV, barriers to remaining adherent may be overcome by the implementation of targeted interventions delivered via mobile devices. This systematic review is focused specifically on mobile phone technologies to deliver adherence interventions in HIV/acquired immunodeficiency syndrome (AIDS) populations.
This review (PROSPERO #CRD42017065131) systematically extracted data from published literature from five databases on mobile phone interventions to improve adherence to ART for HIV. The reported studies had been conducted between 2007 and 2017. Risk of bias was assessed using the Cochrane method ranking each criterion as low, high, or unclear risk of bias.
Of the 835 articles returned, we identified 26 randomized controlled trials (RCTs), retrospective and prospective cohort trials, or mixed method studies with a comparison group that fit criteria for inclusion. No standard measure of adherence was consistent throughout the examined studies, and assessments by self-report, pill counting, and medication event monitoring system (MEMS) were utilized. The studies reported mixed results, with 17 reporting significant improvements to adherence, 3 reporting improvements without supplying p-values, and 6 reporting no significant change or a reduction in adherence.
The mixed nature of the results exemplifies the need for more comprehensive approaches and larger scale trials to confirm results observed in limited cohort sizes. To better retain satisfactory adherence within the HIV population, and especially in low-resource settings, we recommend that future interventions incorporate multiple strategies: mobile-based reminders, social support structures, and personalized content.
Request Full Text via ResearchGate%B Journal of Applied Clinical Informatics %V 9 %P 450-466 %G eng %U https://www.thieme-connect.com/DOI/DOI?10.1055/s-0038-1660516 %N 2 %0 Book Section %B Cognitive Informatics in Health and Biomedicine: Understanding and Modeling Health Behaviors %D 2017 %T Culturally Appropriate Behavioral Change in Maternal Health: Role of Mobile and Online Technologies Over Time %A Yuri Quintana %A Jennifer McWhirter %X
A major challenge in global health is improving newborn and maternal health. A variety of economic, geopolitical, socio-cultural, and technical factors are involved. Online and mobile technologies hold the potential to improve maternal and newborn health by supporting access to education, improving coordinated care, and facilitating patient support. These online and mobile systems have been designed to address a variety of maternal and newborn health outcomes, including: increasing antenatal care attendance; cessation of unhealthy behaviors, such as smoking and drinking alcohol; and increasing vaccination rates of newborns. The success of these systems, however, is very much dependent on how—and whether—they can effect behavioral changes in culturally appropriate ways. This chapter reviews the design of these systems in both developed and developing countries, the technologies and behavioral frameworks used, and the evaluation outcomes. The acceptance of these new patient support networks requires the trust of patients and healthcare providers. Hence, this chapter also reviews the evolution of these systems, and the potential benefits of, and challenges for, their sustained operation.
Request Full text via Research Gate%B Cognitive Informatics in Health and Biomedicine: Understanding and Modeling Health Behaviors %I Spinger %P 213-233 %G eng %U https://link.springer.com/chapter/10.1007/978-3-319-51732-2_10 %0 Book %D 2017 %T Serious Games for Health: Mejora tu salud jugando %A Yuri Quintana %A Oscar Garcia %X
Los juegos aplicados en salud educan, entretienen y favorecen un mejor acceso de los usuarios al mundo sanitario en todas sus vertientes. Además, para este sector suponen una oportunidad sin precedentes en lo relativo a la motivación y el cambio de conducta de las personas en relación a sus enfermedades y dolencias. Estos juegos se diseñan para promover mejores resultados en la salud de los pacientes, para mejorar la formación de los profesionales implicados y promover la educación al servicio de la salud. La industria del juego aplicado en salud está valorada en miles de millones de euros y dispone de centenares de productos y prototipos que se han diseñado desde los ámbitos académico y comercial. Este libro analiza las mejoras en el sector y nos proporciona un marco de evaluación, diseño y estrategia que además quiere ser sostenible.
The book is available for ordering online at this web page and Amazon in Spain and USA.
Serious games for health educate, entertain and improve access to healthcare services. In addition, they represent an unprecedented opportunity to motivate and change people's behavior in relation to their illnesses and conditions. These games are designed to promote better health outcomes for patients, and also to improve the training of the professionals involved in promoting education and health services. The health gaming industry is valued at billions of euros and has hundreds of products and prototypes that have been designed from the academic and commercial fields. This book analyzes the improvements in the sector and provides us with an evaluation, design and strategy framework for sustainable systems%7 1 %I Gedisa %C Barcelona, Spain %G eng %U http://www.gedisa.com/ficha.aspx?cod=500456&titulo=Serious-Games-for-Health#.WQc_h8m1sUE %0 Conference Proceedings %B Stud Health Technol Inform. 2017 %D 2017 %T InfoSAGE: Use of Online Technologies for Communication and Elder Care %A Yuri Quintana %A Crotty, Bradley H %A Darren Fahy %A Alex Orfanos %A Ruchira Jain %A Eli Kaldany %A Lipsitz, Lewis %A Diane Engorn %A Jorge Rodriguez %A Frank Pandolfe %A Adarsha Bajracharya %A Slack, Warner V %A Safran, Charles %X
Aging creates new information and communication needs for families who are helping to coordinate care for frail parents. To identify how information and communication needs evolve with the aging process, we created a living laboratory of families, supported by an online private social network with tools for care coordination. Site registrants are invite to participate in a more in-depth survey-based longitudinal study. In year one, we assessed the feasibility of an online living laboratory. During this first year, 155 individuals registered on InfoSAGE, and 26% opted into the more in-depth longitudinal study. The survey response rate for those in the study was 61%. We present here a descriptive analysis of our early participants and networks, as well as barriers to participation that the study team encountered.
PubMed PMID: 28186055.
View Full text%B Stud Health Technol Inform. 2017 %C Victoria, BC, Canada %V 234 %P 280-285 %G eng %0 Book Section %B Global Health Informatics %D 2017 %T Global Health Informatics—An Overview %A Yuri Quintana %A Safran, Charles %X
Global Health Informatics is a growing multidisciplinary field that combines research methods and applications of technology to improve healthcare systems and outcomes. Healthcare systems are facing many challenges including a growing population, the increasing complexity of care services, and limited resources to deliver services. These challenges will require more innovative approaches to scale healthcare services to larger numbers of people. This chapter outlines health informatics systems that have been developed to address these problems.
Full text%B Global Health Informatics %7 1 %I Elsevier %C New York, NY %G eng %U https://www.elsevier.com/books/global-health-informatics/marin/978-0-12-804591-6 %0 Journal Article %J Journal of Cancer Education %D 2016 %T St. Jude Cancer Education for Children Program: The Impact of a Teacher-Led Intervention on Student Knowledge Gains %A Katherine Ayers %A Zhenghong Li %A Yuri Quintana %A Aubrey Van Kirk Villalobos %A James L. Klosky %X
In 2006, St. Jude Children's Research Hospital (Memphis, Tennessee) began developing a school-based outreach program known as the St. Jude Cancer Education for Children Program (SJCECP). The aim of this program is to teach Memphis-area children about cells, cancer, and healthy habits that can prevent the development of cancer in adulthood. Initial plans for delivery of the program was for St. Jude staff to present the program at local schools. This plan for disseminating instruction was not feasible due to the limited availability of St. Jude staff. As a next step, during the 2012–2014 academic years, we conducted a study entitled SJCECP2, utilizing the SJCECP curriculum, with the objective of evaluating the impact of the educational intervention on knowledge acquisition and retention among fourth-grade students participating in a modified, teacher-led version of the program. Eighteen teachers and 426 students from 10 local schools in the greater Memphis area participated in the program evaluation. This study used a single-group, pre-test/post-test design to determine the impact of the SJCECP intervention on changes in knowledge scores among fourth-grade students. Testing was on cells, cancer, and healthy living. The mean scores increased from 6.45 to 8.12, 5.99 to 7.65, and 5.92 to 7.96 on cell, cancer, and health behaviors units, respectively (all p values <.001). Preliminary evidence suggests that the SJCECP2 intervention is a useful tool for teachers to improve student knowledge of knowledge of cells, cancer, and healthy living concepts at the fourth-grade level.
PubMed: 26939672%B Journal of Cancer Education %P 1-6 %G eng %U https://link.springer.com/article/10.1007%2Fs13187-016-1010-9 %0 Book Section %B Research on the use of Information and Communication Technologies in Brazilian health facilities - ICT in health 2014 %D 2015 %T eCare at a Distance: Opportunities and Challenges %A Yuri Quintana %A Safran, Charles %X
People-centered health care seeks an active role for the patient while empowering all other members of the health care team. By promoting greater patient responsibility and optimal usage, patient-centered health care leads to improved health outcomes, quality of life and optimal value for health care investment. This paper reviews some definitions of people-centered health care and various e-health approaches around the world used to implement this vision. The barriers and enablers to implementation this type of approach are explored. This paper provides a proposed research agenda for future implementations of people-centered e-health.
PubMed PMID: 26262279
Full Text%B MEDINFO 2015 Congress - MEDINFO 2015 Congress %7 216 %I ISO Press %V Stud Health Technol Inform %P 977 %G eng %U http://ebooks.iospress.nl/publication/40437 %0 Journal Article %J J Pediatr Hematol Oncol %D 2015 %T Ethical Decision Making About End-of-life Care Issues by Pediatric Oncologists in Economically Diverse Settings %A Ana M. Sanchez Varela %A Liza-Marie Johnson %A Javier R. Kane %A Kimberly A. Kasow %A Yuri Quintana %A April Coan %A Ying Yuan %A Raymond Barfield %A Christopher Church %A Micah Hester %A Justin N. Baker %X
Translational Collaboration Platforms connect clinical, genomics, and patient-reported data for the advancement of biomedical research, providing an opportunity to speed up the translating of basic science findings into clinical applications and new medicines. These platforms bring together data from both clinical and research databases and provide opportunities for multi-disciplinary research. Recent years have seen a significant growth of these platforms and some global collaborations research networks have been established using these platforms. In this brief summary of these platforms, we examine the challenges in implementation for global international research collaborations and challenges for the sustainability of research networks.
PubMed PMID: 26798845; PubMed Central PMCID: PMC4717481.
Full Text%B MOJ Proteom Bioinform. 2015;2(6):65. %V 2 %P 65 %G eng %N 6 %0 Journal Article %J Journal of the Association of Information Systems %D 2014 %T IT and Agility in the Social Enterprise: A Case Study of St. Jude Children's Research Hospital's 'Cure4Kids' IT-Platform for International Outreach %A Sandra Richardson %A Shane Banks %A Willam Kettinger %A Yuri Quintana %B Journal of the Association of Information Systems %V 15 %P 1-32 %G eng %U http://aisel.aisnet.org/jais/vol15/iss1/2/ %N 1 %0 Journal Article %J Stud Health Technol Inform %D 2013 %T POND4Kids: A Global Web-based Database for Pediatric Hematology and Oncology Outcome Evaluation and Collaboration. %A Yuri Quintana %A Aman N. Patel %A Federico G. Antillon %A Raul C. Ribeiro %A Scott C. Howard %X
The Pediatric Oncology Network Database, (www.pond4kids.org, POND), is a secure, web-based, multilingual pediatric hematology/oncology database created for use in countries with limited resources to meet various clinical data management needs including cancer registration, delivery of protocol-based care, outcome evaluation, and assessment of psychosocial support programs. Established as a part of the International Outreach Program at St. Jude Children's Research Hospital in Memphis, Tennessee, POND serves as a tool for oncology units to store patient data for easy retrieval and analysis and to achieve uniform data collection to facilitate meaningful comparison of information among centers. Launched in 2003, POND now has 233 sites registered with over 1,000 users in 66 countries. However, adoption and usage of POND varies widely among sites. This paper reviews some of the challenges to developing a global collaborative clinical platform based on the experiences of developing POND. The paper also presents a case study of POND use in Guatemala, where the Guatemalan National Oncology Unit (UNOP) has developed extensive internal and external global collaborations using POND.
PMID: 23388293%B Stud Health Technol Inform %V 183 %P 251-256 %G eng %U https://www.ncbi.nlm.nih.gov/pubmed/?term=23388293%5Buid%5D %0 Book %D 2012 %T Advancing Cancer Education and Healthy Living in Our Communities: Putting Visions and Innovations into Action %E Yuri Quintana %E Aubrey Van Kirk %E Dorothy Ogdon %X
Over half the deaths from disease in the world are now due to just four chronic conditions – diabetes, lung diseases, some cancers and heart disease. Health and education are inextricably linked. Developing and delivering effective, scalable and sustainable education programs which lead to real behavioral change would influence some of the common risk factors for these diseases, such as smoking, poor diet and lack of physical activity. This book contains the selected papers from the St. Jude Cure4Kids Global Summit, held in June, 2011 at St. Jude Children's Research Hospital in Memphis, Tennessee, USA. The aim of this three-day conference was to improve health and science education in classrooms and communities around the world. Leading educators, innovators and pioneers in the field of public health came together in a multidisciplinary forum to explore examples of successful education programs, analyze the challenges in designing effective, scalable and cost-efficient public health education programs and identify strategies, methodologies and incentives for developing future programs capable of yielding large-scale improvements in health outcomes for diverse communities. The papers presented here provide a foundation in the key topics necessary to create future innovative health promotion programs, and will be of interest to all those whose work involves improving health outcomes by means of better and more effective health education.
Book Available at Amazon and the Publisher Site%I IOS Press %C Amsterdam %G eng %U https://www.amazon.com/Advancing-Cancer-Education-Healthy-Communities/dp/1614990875 %0 Journal Article %J British Medical Journal Satellites %D 2011 %T People-Centred Healthcare systems: opportunities and challenges %A Yuri Quintana %A Nancy Lorenzi %A Mordechai Shani %X
People-centered health care systems aim to empower people with their health care decisions, make information more accessible, and enable more autonomy. The goal is to promote well-being as much as to treat disease, and to create more collaboration between providers, patients, and their families, thus reducing costs and improving health outcomes. Throughout the world growing populations and rising costs are challenging health care systems. In numerous countries, health care providers are unable to meet the needs of many individuals and groups due to limited budgets, time, and staff. An aging population and rapidly increasing rates of chronic diseases could overwhelm most health care systems. While information and communication technologies can connect health care providers with each other and the consumers they serve, there is no group, organization, or government that has successfully overcome the roadblocks to implementing a wide people-centered health system. Ideally, such a system would put the needs of the public first, enable individuals to take greater responsibility for managing their own health and health services, and promote optimal levels of health and resource utilization. In this paper, we explore a vision for future people-centered health care systems that could provide better access to information and decision-making tools for patients, health care providers, and the general public. We also examine key challenges to creating such systems.%B British Medical Journal Satellites %V 18 %P 17-24 %G eng


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This is the place where Rama created a bridge across the sea to reach Sri Lanka. As the world's economy slowly recovers, consumers should take comfort in the fact that there are a lot government and private aid available for them to take advantage of in order to successfully negotiate their debt relief problems. You expect that it will be difficult to persuade them to look for the hard drive, especially because you have no money to pay them with. Keep in mind it may be difficult to pay the loan back in the early years before your small business really takes off. The company has experienced some customer service issues in the past. Not sure why Dave doesn't have an extra Step in here, as he does mention on free newsletter app show to save up for a house at this point. See more in the end, you bury yourself deep- down the piles free newsletter app never-ending bills and charges, not knowing how and where to find the money to pay off these debts.
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Deadline for submitting presentation is 20th November!
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28th November 2019 - 30th November 2019 6th Lublin International Medical Congress for Students and Young Doctors


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Cervical insufficiency. Sometimes we do use a trimester system if we are seeking to describe how far along a woman is in general terms. No part of this publication may be reproduced, stored in a retrieval system, posted on the Internet, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without prior written permission from the publisher. Cardiac ICU. Evaluation and general management of patients with and at risk for AKI.
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Research Topics
Genomes and Genes
Gene Symbol: ninaB
Description: neither inactivation nor afterpotential B
Alias: CG9347, DRPE65, Dmel\CG9347, RPE65, anon-WO0148162.1, anon-WO0148163.1, beta-diox, neither inactivation nor afterpotential B, CG9347-PA, beta-carotene dioxygenase, ninaB-PA
Species: fruit fly
Top Publications
More Information
- Halme A, Cheng M, Hariharan I. Retinoids regulate a developmental checkpoint for tissue regeneration in Drosophila. Curr Biol. 2010;20:458-63 pubmed publisher..Our findings demonstrate that retinoid biosynthesis in Drosophila is important for the maintenance of a condition that is permissive for regenerative growth. ..
- Ranganathan R, Harris W, Zuker C. The molecular genetics of invertebrate phototransduction. Trends Neurosci. 1991;14:486-93 pubmed..The results of a combination of molecular, genetic, physiological and biochemical studies are beginning to produce a clearer model for the complex mechanisms involved in invertebrate visual transduction. ..
- Selinger Z, Doza Y, Minke B. Mechanisms and genetics of photoreceptors desensitization in Drosophila flies. Biochim Biophys Acta. 1993;1179:283-99 pubmed
- Krstic D, Boll W, Noll M. Influence of the White locus on the courtship behavior of Drosophila males. PLoS ONE. 2013;8:e77904 pubmed publisher..Implications of these findings for the proper interpretation of behavioral studies with white mutant flies are discussed. ..
- Kim W, Jan L, Jan Y. Contribution of visual and circadian neural circuits to memory for prolonged mating induced by rivals. Nat Neurosci. 2012;15:876-83 pubmed publisher..Our study thus delineates parts of the molecular and cellular basis for LMD, a plastic social behavior elicited by visual cues. ..
- Peschel N, Veleri S, Stanewsky R. Veela defines a molecular link between Cryptochrome and Timeless in the light-input pathway to Drosophila's circadian clock. Proc Natl Acad Sci U S A. 2006;103:17313-8 pubmed
- Kacsoh B, Lynch Z, Mortimer N, Schlenke T. Fruit flies medicate offspring after seeing parasites. Science. 2013;339:947-50 pubmed publisher..Our data reveal a behavioral immune response based on anticipatory medication of offspring and outline a nonassociative memory paradigm based on innate parasite recognition by the host. ..
- Voolstra O, Oberhauser V, Sumser E, Meyer N, Maguire M, Huber A, et al. NinaB is essential for Drosophila vision but induces retinal degeneration in opsin-deficient photoreceptors. J Biol Chem. 2010;285:2130-9 pubmed publisher..related enzymes, the carotenoid oxygenase beta-carotenoid-15,15'-monooxygenase and the retinoid isomerase RPE65 (retinal pigment epithelium protein of 65 kDa)...
- Oberhauser V, Voolstra O, Bangert A, von Lintig J, Vogt K. NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide. Proc Natl Acad Sci U S A. 2008;105:19000-5 pubmed publisher..Evidence from cell culture systems has implicated that the retinal pigment epithelium protein of 65 kDa (RPE65) is the long-sought all-trans to 11-cis retinoid isomerase...
- Wang T, Jiao Y, Montell C. Dissection of the pathway required for generation of vitamin A and for Drosophila phototransduction. J Cell Biol. 2007;177:305-16 pubmed..The protein is coexpressed and functionally coupled with the beta, beta-carotene-15, 15'-monooxygenase, NINAB, which converts beta-carotene to all-trans-retinal...
- Yang J, O Tousa J. Cellular sites of Drosophila NinaB and NinaD activity in vitamin A metabolism. Mol Cell Neurosci. 2007;35:49-56 pubmedThe Drosophila genes ninaB and ninaD, encoding a beta-carotene oxygenase and a type B scavenger receptor respectively, are essential for the biosynthesis of the 3-hydroxyretinal chromophore of rhodopsin...
- Zuker C. Phototransduction in Drosophila: a paradigm for the genetic dissection of sensory transduction cascades. Curr Opin Neurobiol. 1992;2:622-7 pubmed..The availability of Drosophila mutants with defects in visual physiology allows for an in vivo dissection of this complex sensory signal transduction process. ..
- Meyer N, Joel Almagor T, Frechter S, Minke B, Huber A. Subcellular translocation of the eGFP-tagged TRPL channel in Drosophila photoreceptors requires activation of the phototransduction cascade. J Cell Sci. 2006;119:2592-603 pubmed..The critical role of Ca2+ influx was directly demonstrated when the light-induced TRPL-eGFP translocation was blocked by removing extracellular Ca2+. ..
- Kacsoh B, Bozler J, Ramaswami M, Bosco G. Social communication of predator-induced changes in Drosophila behavior and germ line physiology. elife. 2015;4: pubmed publisher..The ability to teach does not require ovarian apoptosis. This work provides new insight into genetic and physiological mechanisms that underlie an ecologically relevant form of learning and mechanisms for its social transmission. ..


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