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Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.
A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia
Full Title of Study: "A Safety and Effectiveness Study of Intratumoral Diffusing Alpha Radiation Emitters for the Treatment of Malignant Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia"
Study Type
- Study Type: Interventional
- Study Design
- Allocation: N/A
- Intervention Model: Single Group Assignment
- Primary Purpose: Treatment
- Masking: None (Open Label)
- Study Primary Completion Date: January 2022
Detailed Description
This will be a prospective, open label, single arm, controlled study, assessing the safety and efficacy of diffusing alpha emitters radiation therapy (DaRT) delivered through radioactive seeds inserted into the tumor.
This approach combines the advantages of local intratumoral irradiation of the tumor, as used in conventional brachytherapy, with the power of the alpha radiation emitting atoms, that will be introduced in quantities considerably lower than radiation therapy already used in patients.
Superficial lesions with histopathological confirmation of malignancy will be treated using DaRT seeds.
Reduction in tumor size 70 days after DaRT insertion will be assessed. Safety will be assessed by the incidence, severity and frequency of all Adverse Events (AE).
- Device: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
- An intratumoral insertion of a seed(s), loaded with Radium-224, securely fixed in the seeds. The seeds release by recoil into the tumor short-lived alpha-emitting atoms.
Arms, Groups and Cohorts
- Experimental: DaRT Seeds
- Intratumoral Diffusing alpha-emitters Radiation Therapy (DaRT) Seeds
Clinical Trial Outcome Measures
Primary Measures
- Tumor response to DaRT
- Time Frame: 9-11 weeks after DaRT seed insertion.
- Assessment of the rate of malignant cutaneous, mucosal or superficial soft tissue tumors response using the Response Evaluation Criteria in Solid Tumors (RECIST) (Version 1.1)
- Adverse Events
- Time Frame: Time Frame: 9-11 weeks post DaRT insertion.
- The incidence, frequency, severity and causality of acute adverse events related to the DaRT treatment
Secondary Measures
- Assessment of the reduction in tumor volume
- Time Frame: 9-11 weeks follow-up visit.
- Assessment of the reduction in tumor volume based on CT / PET-CT measured tumor volume
- DaRT seeds placement.
- Time Frame: Day of insertion procedure.
- Assessment of the DaRT seeds placement by localization of the DaRT seeds in the tumor using CT imaging on the day of DaRT insertion.
- Change in quality of life
- Time Frame: Screening, DaRT removal and day 70 visits.
- Assessment of patient reported health-related Quality of Life outcome after DaRT, using QoL questionnaire Skindex-16 questionnaire score. An overall score ranging from 0 (best) to 100 (worst).
- Change in quality of life
- Time Frame: Screening, DaRT removal and day 70 visits.
- Assessment of patient reported health-related Quality of Life outcome after DaRT, using QoL questionnaire Skin Cancer Index (SCI) questionnaire score. An overall score ranging from 0 (best) to 100 (worst).
Participating in This Clinical Trial
Inclusion Criteria
- Subjects with histopathological confirmation of primary or secondary malignant cutaneous neoplastic lesions, or oral cavity mucosal tumors, or superficial soft tissue sarcoma.
- Subjects with a tumor size ≤ 7 centimeters in the longest diameter.
- Measurable disease according to RECIST v1.1.
- Subjects over 18 years old.
- Subjects' ECOG Performance Status Scale is < 2.
- Subjects' life expectancy is more than 6 months.
- Platelet count ≥100,000/mm3.
- International normalized ratio of prothrombin time ≤1.8.
- Creatinine ≤1.9 mg/dL.
- Women of childbearing potential (WOCBP) will have evidence of negative pregnancy test.
- Subjects are willing to sign an informed consent form.
Exclusion Criteria
- Subject has a tumor of Keratoacanthoma histology.
- Patients with significant comorbidities that the treating physician deems may conflict with the endpoints of the study (e.g., poorly controlled autoimmune diseases, vasculitis, etc.)
- Patients undergoing systemic immunosuppressive therapy excepting intermittent, brief use of systemic corticosteroids
- Volunteers participating in another interventional study in the past 30 days which might conflict with the endpoints of this study or the evaluation of response or toxicity of DaRT.
- High probability of protocol non-compliance (in opinion of investigator).
- Subjects not willing to sign an informed consent.
- Women who are pregnant or breastfeeding.
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: N/A
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- Alpha Tau Medical LTD.
- Provider of Information About this Clinical Study
- Sponsor
- Overall Official(s)
- Tomer Charas, MD, Principal Investigator, Radiotherapy unit at Rambam Health Care Campus, Israel
- Overall Contact(s)
- Naama Barel, +972-3-618-24770, firstname.lastname@example.com
Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.


text:
Remember Shakti
© Ridvan Yumlu. All Rights Reserved.
If you are the rightful owner of this image and are not credited, contact us.
All About Jazz / Vision X Software is a DMCA designated agent.
About this image
Remember Shakti performing at the Ramallah Cultural Palace, in the Palestinian Territories
Uploaded: 2012-02-26
Size: 1,023 x 631 pixels

subset: commoncrawl


text:
- Dependable Hurricane Impact Windows in Elm Grove, WI
- Local in Elm Grove, WI Hurricane Impact Window Experts
- Free Estimates on Hurricane Impact Windows in Elm Grove, WI
Top Quality Hurricane Impact Windows in Elm Grove for the Right Price
Call Now (888) 907-5667
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Find the Best Costs on Hurricane Impact Windows - Elm Grove, WI
You will find that Elm Grove hurricane impact windows are a great investment to make, especially if you are concerned about security. These windows do not break easily at all, so you won't have to worry about someone getting into your home, such as a burglar. Impact windows are designed to withstand the extremely strong winds of hurricanes, which is why you won't have to worry about taking the time and effort to board yours up anymore when a hurricane is expected to hit. These windows will also provide you with an additional layer of soundproofing that will keep out noises so you will have a much easier time relaxing in your house.
Elm Grove Hurricane Impact Windows FAQ
Why should I have Elm Grove hurricane impact windows installed on my home?
The hurricane impact windows Elm Grove, WI has to offer can provide your home with additional protection from the extremely high winds that are associated with severe weather. Many people who live in areas where hurricanes are fairly common end up spending a lot of money replacing their windows because of these storms, but with hurricane impact windows in Elm Grove, WI you will no longer have to do that. With these windows on your home you will also not have to worry about boarding them up when a hurricane is expected to hit, as they will be able to withstand the high winds.
How much will I pay for hurricane impact windows in Elm Grove, WI?
The total cost of hurricane windows depends on a number of factors, such as how many you need as well as the specific ones you choose to have installed. These windows are typically priced at around $550 and up, but you will definitely get your money's worth because of all the protection they offer. Hurricane impact windows in Elm Grove, WI are reinforced with extremely durable materials to ensure that they will last through even the most violent storms. And although the cost of these windows might be significantly higher than most others, they are well worth the additional expense because of the benefits they offer.
What are some of the primary benefits of hurricane impact windows in Elm Grove, WI?
One of the primary benefits that Elm Grove hurricane impact windows offer is that they will continue to stand strong even through severe weather. Another benefit of these windows is that they offer protection against burglars and all other forms of intruders. Because these windows are so incredibly difficult to break, you will not have to worry about anyone getting into your house through the windows. Overall, hurricane impact windows in Elm Grove, WI have a lot to offer homeowners.
Hurricane Impact Windows Companies
Palace Windows Inc.
4545 W Burnham St
Milwaukee, WI 53219
Ruebl Builders
Sunset Dr
East Troy, WI 53122
J & J Roofing & Siding
Brook Ct
Waukesha, WI 53189
Veteran Home Improvements Llc
P.O Box 510568
New Berlin, WI 53151
Laforce Inc.
N58w16780 Ridgewood Dr
Menomonee Falls, WI 53051
Meckelburg Sash & Door Div of Getzel Corp The
2715 S 28th St
Milwaukee, WI 53215
Related Services
Cities We Service
Hurricane Impact Windows in Wisconsin
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- 53122, 53005, 53007, 53146, 53202, 53051, 53130, 53186, 53046, 53129, 53072, 53089


text:
Just unpack and settle in to this immaculate, bright, ranch style home located in the Great Plain neighborhood in Danbury. This well-maintained home has been completely painted and is move-in ready. The main level offers an open, bright living room, dining room, eat-in kitchen with stainless appliances, master bedroom with en-suite master bathroom, 2 additional bedrooms, hall bath, and gleaming wood floors throughout. Step down to the lower level and find a terrific recreation room complete with dry bar and walk-out leading to a private, screened in patio. Huge storage room, laundry area with sink, a walk-In cedar closet, one-car garage, and new furnace and hot water heater (2018) complete the picture. All of this and centrally located with easy access to Candlewood Lake, terrific shopping, college, hospital, downtown area, dining and I84. Welcome home!
Whether you're in the research phase beginning your real estate journey or you know exactly what you're looking for, you'll benefit from having a real estate professional by your side.


text:
We took our son to a splash park tonight at a local mall, totally on a whim. We knew he'd have a blast, so we finished up at our restaurant and promised that a "surprise" awaited him. He was excited and very, very curious. When he saw the fountains springing from the concrete and the myriad of children laughing, running, and playing, he knew just what he wanted to do. With widened eyes, he said with extreme excitement, "Where's my SWIMSUIT, I wanna PLAY!" His joy gave us joy. We said, "don't worry about a swimsuit, we'll just dry you off in the car. Go and play!"
Micah was a little bewildered. "But I'll get wet…I need my swimsuit." He knows that getting his clothes wet is a no-no at home, but in the midst of his worry about breaking our rules, he wasn't embracing that the rule-makers were giving him permission to go and play. He kept fretting about getting wet. We said "go and play!" He walked cautiously to the first fountain and gingerly stuck his toe into it, cautiously scanning our faces for the go-ahead. Our smiles and nods told him that it was time to put his leg into the spewing water cannon emanating from the ground. We said "go and play!" He looked at us again, searching for permission to break the rules. We again nodded and smiled. We said "go and play!" He interpreted this final nod as the greenlight for Operation Splashbody, running full-bore into the drenching center of the park: a pumping, pulsing urban geyser which soaks anyone who comes near. He no longer looked for our approval of every step. He finally stopped thinking of the rules and started listening to the call of the rule-maker: "Go and play!"


text:
The Graphic Neck Gaiter with Coolcore Technology features innovative fabric to help regulate temperature for year-round comfort. This lightweight riding accessory is designed with extra length for added versatility. It tucks inside your jacket and collar to block wind. Wear over your mouth and nose to repel dust and bugs. Or slide it over your head as a do-rag (CONFIRM - per KPM).
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Accelerated dryland expansion under climate change (Nature- Climate Change)
Drylands are home to more than 38% of the total global population and are one of the most sensitive areas to climate change and human activities. Projecting the areal change in drylands is essential for taking early action to prevent the aggravation of global desertification.
However, dryland expansion has been underestimated in the Fifth Coupled Model Intercomparison Project (CMIP5) simulations considering the past 58 years (1948–2005). Here, using historical data to bias-correct CMIP5 projections, we show an increase in dryland expansion rate resulting in the drylands covering half of the global land surface by the end of this century.
Dryland area, projected under representative concentration pathways (RCPs) RCP8.5 and RCP4.5, will increase by 23% and 11%, respectively, relative to 1961–1990 baseline, equalling 56% and 50%, respectively, of total land surface. Such an expansion of drylands would lead to reduced carbon sequestration and enhanced regional warming, resulting in warming trends over the present drylands that are double those over humid regions.
The increasing aridity, enhanced warming and rapidly growing human population will exacerbate the risk of land degradation and desertification in the near future in the drylands of developing countries, where 78% of dryland expansion and 50% of the population growth will occur under RCP8.5.


text:
Summer Internship in Smart Materials and Adaptive Structures
Located in Malibu, California, HRL has been on the leading edge of technology, conducting pioneering research and advancing the state of the art.
EDUCATION DESIRED: The candidate should be in the process of getting their BS or MS in mechanical engineering, aerospace engineering, engineering mechanics, material science, electrical engineering or related discipline.
ESSENTIAL JOB FUNCTIONS: We are looking for motivated candidates interested in experiencing the design-build-test cycle of first-of-its kind prototypes in the field of smart materials and adaptive structures.You will be a part of a diverse team of scientists and engineers researching new applications of nonlinear dynamics, multiferroic, and multi-functional materials for vibration isolation, sensing, and communication.The ideal candidate has creative problem solving skills, hands-on prototyping experience, and the ability to work effectively on a team and independently.
A typical set of tasks for this job include new concept brainstorming, modeling and simulation (CAD, FEA, Matlab), procurement of hardware, interfacing with the machine shop, and electromechanical device assembly, instrumentation and testing.Test activities include operating load frames and electrodynamic shakers and data acquisition verifying the performance of electromechanical devices including measurement of power, temperature, strain, acceleration, and modal response.
EXPERIENCE DESIRED: The candidate should have experience as a strongly contributing member of a product development team designing and prototyping electromechanical devices.Experience in a university research lab, national lab, or similar organization is also desirable.
ESSENTIAL PHYSICAL/MENTAL REQUIREMENTS: Application must be capable of working safely in a laboratory and performing extended analysis at computer workstations.
SPECIAL REQUIREMENTS (e.g. driver's license special tools or restrictions): U.S. citizenship or permanent resident status required.
Selected candidates will be hired through a temporary agency and subject to the agency's pre-employment substance abuse testing.
Other details
- Pay Type Hourly
- Employment Indicator Internship
- Malibu, CA, USA


text:
2019 Economic Forecast
Last March, Robert Aliber, Professor Emeritus of International Economics and Finance at The University of Chicago Booth School of Business, foresaw the decline in financial markets in 2018.
Prof. Aliber, once again, uncensored, pulled no punches last March at our 2018 Economic Forecast. Prof. Aliber predicted the erosion of assets values in financial markets, as the U.S. dollar gains finally slowed with trade and fiscal deficits persisting. Back by popular demand, Prof. Aliber once again comes out of retirement to share his unique economic outlook, independent of conventional, popular press group think. His refreshing, bold market calls have become legendary among Dallas-Ft. Worth alumni. Is the worst still yet to come in stock and bond markets? Will the U.S. dollar finally fall under the weight of mounting deficits? Will the China real estate and credit bubble ever burst? Will oil and other commodities continue to be dead money? Ask Prof. Aliber about his current views on the future of stocks, bonds, oil, gold or your personal finance decisions.
11:30 am - Registration begins
12 noon - Plated lunch served
12:30 pm - Prof Aliber Remarks and Q&A
Speaker Profile
Robert Z. Aliber, Professor Emeritus of International Economics and Finance, The University of Chicago Booth School of Business
Professor Robert Z. Aliber received the Ph.D degree from Yale University in 1962 and Bachelors degrees from Williams College and Cambridge University. He joined the faculty of The University of Chicago Booth School of Business in 1965 and retired in 2004 as Professor of International Economics and Finance. Prior to joining the Chicago faculty, Aliber was Senior Economic Advisor, Agency for International Development, Department of State.
Bob was the National Westminster Professor of International Finance at the London Business School in 1978, the Bundesbank Professor at the Free University of Berlin in 1997, and a visiting Professor at the Amos Tuck School of Business at Dartmouth College in the early 1980s and again in 2004; he was also a visiting professor at Brandeis University and at Williams College. Bob was the Houblon-Norman fellow at the Bank of England in 1996. He was the JPMorgan Prize Fellow at the American Academy in Berlin in 2003 and a visiting scholar at the Woodrow Wilson Center for International Scholars in Washington in 2004. Aliber has been a visiting scholar at the Federal Reserve Bank of San Francisco, and a consultant to the World Bank and the International Monetary Fund and a various think tanks in Washington and London.
Aliber has written extensively about international financial issues, including changes in cross-border capital flows and changes in currency values; and the efficiency of the currency market. His publications include The New International Money Game (7th edition 2010), The Multinational Paradigm (1995) and Maniacs, Panics and Crashes (6th edition 2010). In the early 1980s, he wrote a book on personal finance, Your Money and Your Life (re-published by Stanford University Press 2010). He is the co-editor of a collection of papers and reports that were published prior to the Iceland's financial crisis.
Bob founded Dorchester Capital Management in 1991, which provides asset management and financial planning service.
Event Information
General admission pricing only available through February 1st:
$60 for UChicago and Chicago Booth alumni, students and parents
$65 for non-alumni friends
(Non-alumni, please call 773-702-2150 to register)
$480 for one whole table, seats 8
After February 1st:
$70 event-day tickets and walk-ins.
12:30PM - 2:30PM Fri 8 Feb 2019 ( Timezone: Central )
Four Seasons Las Colinas
4150 N. MacArthur Blvd
Irving , TX 75038 USA
[ Get Directions ]
Look Who's Coming:
Pariveda Solutions
BBVA Compass
Southwest Airlines
Strongside Financial
Energy Capital Solutions
Blackland Capital Partners
Jack Henry and Associates
Merrill Lynch
Carlson Capital, L.P.
Gartner, Inc.
Course & Club
CB JENI Homes
Trinity Basin Preparatory
Liberty Capital Bank
A+ Charter Schools
Retired: Briggs International
BB&T Capital Markets
Dynamic Support Solutions
Trinity Basin Preparatory
Molli - True Mexican Flavors
Tarrant County College
Delphi Behavioral Health Group
(214) 238-3674


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Devin Homan41
The configuration file for that particular Mango install is attached
to ticket 1146 on the support page. We have three TUF meters on a
single RS485 bus that are polled once every five seconds, with a
baud rate of 9600. We see one error about every two days. Mango is
the only master that we have at the install location, with each
meter being a slave to it. We are sometimes making multiple single
register read requests, sending out multiple request packets; we are
not sending multi-register-read requests. We have a number of TUF
meter registers that are persistent and store accumulative values,
so those values are very recognizable when they occur in the wrong
table or when a value not from that register occurs in its
corresponding table. My understanding is that each response packet
from a slave contains a header with the slave id and register id,so it
should be unambiguous to Mango where to store the data.
I'm guessing that this is happening when multiple packets are being
returned from different slaves or from the same slave for different
Devin Homan41
The company I work for is having communication issues between Mango and a number of TUF-2000M meters using ModBus over RS-485. I have issued a ticket, #1146, which contains our Mango's configuration. The issue that we are having is that sometimes data appears to end up in incorrect locations; data that is from one data point ends up in another data point's table. The data is checksummed, so corruption is not the issue. The data is coming from persistent and instantaneous registers, and we are able to see corresponding values in the meters and in Mango sometimes being put in the wrong table, but this only happens occasionally. I was wondering if anyone has noticed similar problems. To me this seems like the kind of problem due to a race condition.


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Mental Health / Counselling - Depression - Child & Youth
|Program Name
|Taking Care: Depression
|TeensHealth: Depression
Page 1 of 1
Mission Residents Looking for a Family Doctor Register today for the family doctor patient referral list. Please note: this Patient Registry is for
Mission residents only.
Mission residents only.


text:
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- Canada's Aviation. PEPPLER, GRAEME // Canadian Aviator;Mar/Apr2009, Vol. 19 Issue 2, p20
The article features the Canada Aviation Museum. The museum's collection of aerial machines and artifacts is housed at the Rockcliffe Airport in Ottawa, Ontario. According to Tony Smyth of Canadian Aviation Museum, the museum's aim is to collect, preserve, display and interpret the aviation...
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Dear Jasonh-san,
Nice photos and great info!
May I ask you a couple of questions?
2: Did you make a careful selection before sowing (sort fine seeds out with care (the stereoscopic microscope ))? Or sowed all seeds you received?
Thank you very much in advance.
Kind regards from the Far East


text:
Murray-Miller on Freundschuh, 'The Courtesan and the Gigolo: The Murders in the Rue Montaigne and the Dark Side of Empire in Nineteenth-Century Paris'
Aaron Freundschuh. The Courtesan and the Gigolo: The Murders in the Rue Montaigne and the Dark Side of Empire in Nineteenth-Century Paris. Stanford: Stanford University Press, 2016. 272 pp. $24.95 (paper), ISBN 978-1-5036-0082-9.
Reviewed by Gavin Murray-Miller (SHARE) Published on H-Empire (August, 2018) Commissioned by Gemma Masson (University of Birmingham)
Printable Version: http://www.h-net.org/reviews/showpdf.php?id=52227
On the night of March 16-17, 1887, Régine de Montille (né Marie Regnault) was found gruesomely murdered in her apartment on the rue Montaigne alongside the bodies of her servant, Anette Gremeret, and Gremeret's young daughter. The apartment was located in the lower Champs-Elysées, a gentrified quarter of the French capital frequented by Parisian elites and wealthy visitors to the city. Evidence at the crime scene quickly revealed that Regnault was a high-class prostitute with an exclusive clientele, making the incident in the rue Montaigne the latest in a string of murders among women of the demimonde dating back at least two years. Within weeks, police had in their custody the handsome Enrico Pranzini, an Egyptian-born Italian who had come to France in 1886 and whom authorities believed responsible for the crime. Triple-homicide, sexual intrigue, and a foreign-born culprit: the murders in the rue Montaigne possessed all the makings of a sensational story destined to enthrall a French public hungry for scandal and gossip.
In The Courtesan and the Gigolo, Aaron Freundschuh seeks to place the rue Montaigne murders within the context of the broader social and political milieu of fin-de-siècle France. Histories of crime and criminality are hardly in short supply when it comes to this well-researched period. The works of Dominque Kalifa, Edward Berenson, and Benjamin Martin have provided excellent studies of the republican justice system and crime during the Third Republic. Adding to this body of scholarship, Freundschuh brings to the table a focus on colonial history and theory in his treatment of the rue Montaigne murders. As he states, his book is intended to serve as a "microhistorical approach to empire" (p. 12). Such an approach is welcome in imperial studies, which often tend to focus on broad structural themes and issues that cut across vast swaths of territory. As a methodology, it offers a promising means of analyzing the precise ways in which colonialism might have engendered feelings of national vulnerability and crisis central to Freundschuh's book. Building upon this conjecture, Freundschuh argues that the rue Montaigne affair demonstrates how xenophobia, racial attitudes, sexual deviancy, and gender converged with colonial influences at the tail end of the nineteenth century. The case and dramatic trial became a manifestation of national anxieties and "imperial insecurity" that blurred the boundaries between metropole and colony and exposed a "darker vision of the age of empire" (p. 11).
Central to Freundschuh's argument is Enrico Pranzini, the leading suspect in the rue Montaigne murders. Following his arrest, Pranzini became a symbol of the many threats the nation faced, whether as a foreign immigrant, an ambiguous "oriental," or a case study in the new racialized theories of criminology emerging at the time. The evidence against Pranzini was circumstantial, and this entailed the prosecution making Pranzini's character and "Laventine" origins a centerpiece of the trial. Freundschuh nicely places these details within the broader context of French cultural and political life. As he notes, the trial occurred during the building of the Eiffel Tower—a monument that provoked heated debates over French identity—and in the midst of the Boulangist threat and rise of the new Right, which was actively whipping up fears regarding foreign and cosmopolitan infiltration. Right-wing publicists used the trial to illustrate the dangers posed by foreigners while authorities and the prosecution employed colonial stereotypes related to criminalized behavior and sexual deviance to emphasize Pranzini's guilt. According to Freundschuh, perceptions of the "cosmopolitan colonial" as a criminal archetype were becoming more pronounced as colonial expansion destabilized concepts of borders and identity in the late nineteenth century. The investigation and trial, in his estimation, underscored the close links "between the colonial and the criminal imaginaries" (p. 199).
One of the more interesting details brought to light in this book is the colonial subculture that existed within the metropolitan police. Marie-François Goron, one of the chief investigators in the case, had served in Algeria and the Antilles prior to joining the metropolitan police force, and as Freundschuh claims, Goron put his colonial knowledge to the test while investigating Pranzini. The transition from colonial official to metropolitan law enforcer was not unique to Goron, hinting at a broader colonial mindset embedded within metropolitan policing at the time. These colonial influences came out in one of the most gruesome details of the Pranzini affair when, following Pranzini's sentencing and execution, leading men within the security force obtained pieces of Pranzini's skin and had it made into decorative cardholders given to the top brass of the metropolitan police. The so-called skin affair elicited a scandal, with the press linking the taking of Pranzini's skin to forms of trophy collection popular on the colonial frontier. Journalists did not fail to remark on the "savage" attributes of such practices, leading Freundschuh to surmise that the skin affair served to feed anxieties over imminently "colonial" influences coming to imprint themselves on the metropole. In no uncertain terms, the skin affair lifted the veil of French civilization to expose the Other beneath, as Freundschu argues.
Freundschuh has written an entertaining and insightful book. Yet at times it seems that the themes of colonialism and anxiety are lost among the accounts of the criminal investigation and Parisian press as Freundschu establishes the details of the case. Mixing a narrative of events with reflections on domestic politics and colonialism, he modulates between giving readers a traditional history of crime and a more analytical study of race, xenophobia, and imperialism. The first half of the book is primarily concerned with following the development of the case, rarely hinting at the broader themes and concepts Freundschuh seeks to address later in his study. The effect tends to leave readers with a feeling that some of Freundschuh's main claims regarding the influence of colonial anxieties might be overstated in places. While fears of imperial insecurity may have loomed over the Pranzini affair, their direct impact on the case and trial seems speculative in many instances and reliant upon Freundschuh's interpretive reading of the event.
This is not to suggest that Freundschuh's detailed examination of the investigation is without merit. His account provides insight into the metropolitan police force, recounting the internal rivalries and subcultures that came to shape criminal investigation in France. The Sûreté—the primary agency dedicated to criminal investigation in France during the nineteenth century—was in a period of transition as the murders of the demimondaines broke. Recently removed from the watchful eye of the municipal police, Sûreté was bent on reforming its image as a corrupt, antirevolutionary arm of the state. The newly appointed chief of security, Ernest Taylor, cultivated the image of a cooperative republican fonctionnaire, an "umbrella inspector," as critics charged. Yet if criminal investigation was attempting to adopt a more professional persona, authorities were forced to confront the newly democratized press, which often competed with criminal investigators for clues and leads. One of the most interesting aspects of Freundschuh's book is its examination of how modern investigative reporting developed in the 1880s alongside the professionalization of the criminal police. Reporters like Georges Grison, who chronicled the rue Montaigne murders for La Figaro, surveilled authorities, printed their own conjectures on cases, and openly hectored officials in their columns. In this evolving relationship between Parisian officialdom and investigative reporters, authorities were forced to come to grips with a democratized press and journalists catering to sensationalism.
Just as intriguing is Freundschuh's examination of the milieu of the Parisian demimonde. His insights are informed by a variety of sources ranging from secret police files to books like The Pretty Women of Paris (1883), a notorious sex guide rating upscale prostitutes. Elite prostitution thrived on networks that brought sex workers to Paris from various parts of the world, with "exotic" women often fetching a high price at the high-end maisons de rendez-vous that typically facilitated sexual encounters. Freundschuh gives a detailed picture of the Parisian sex industry in the late nineteenth century and its place within the world of elite male sociability. He equally provides insight into the lives of elite prostitutes like Marie Regnault. Demimondaines often acquired expensive collections of jewelry, art, and luxury items from clients. Their net worth, as Freundschuh reveals, sometimes rivaled the top income-earners in the country. This conclusion is, in part, ascertained from the inventory lists of auctions held at the Hôtel Drouot, which sold many belongings of demimondaines in the midst of financial troubles or after their death.
For those interested in the history of crime and investigative journalism in late nineteenth-century France, Freundschuh's book will be a pleasure to read. It is short, well-paced, and informative. For those seeking new insights on the French Empire, however, the book may not have as much to offer. While certain aspects of the investigation and trial were shaped by the culture of nineteenth-century imperialism, these elements are often diffuse and spread throughout the story. Pranzini after all was an Egyptian, not a French colonial subject. The xenophobia and racism that Freundschuh critiques were just as much reactions to early globalization and security concerns following the Franco-Prussian War as they were to French empire-building and expansion during the period. These distinctions are never delineated as carefully as they might be by Freundschuh, leaving questions as to whether the many national anxieties he notes were all representative of the "dark side of empire."
Citation: Gavin Murray-Miller. Review of Freundschuh, Aaron, The Courtesan and the Gigolo: The Murders in the Rue Montaigne and the Dark Side of Empire in Nineteenth-Century Paris. H-Empire, H-Net Reviews. August, 2018. URL: http://www.h-net.org/reviews/showrev.php?id=52227This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.


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Tokyo 2020 Olympic Games in danger due to COVID 19 Pandemic – The much-awaited Tokyo 2020 Olympic Games is in danger following the global outbreak of the deadly coronavirus(COVID 19).
The widespread of the virus has indeed affected sporting activities world wide following the postponement and cancellation of some major sporting events such as the Euro 2020, the English Premier League, the Spanish La Liga, and many others.
Since then, there has been intense pressure on the organisers of the Games – Japan and the International Olympic Committee (IOC) to take a definite decision on the event scheduled for July to August, and followed by the Paralympic Games in the same country I, September.
Earlier the Prime Minister of Japan Mr. Shinzo Abe insists the Games would be held as scheduled but recent public pressure made him make a u-turn to say the postponement of the global event is unvoidable, whilst the
IOC President Thomas Bach wants at least four more weeks to determine the future of the event.
According to Prime Minister Abe, whilst canceling the Games was not an option, a delay was now on the cards if that was the only way to hold the events in a complete format.
"If it becomes difficult. we may have no option but to consider postponing the games," he told parliament.
From all indications, Japan which so far recorded over 1000 cases is definitely not in the mood to cancel the Games but postponement.
Their position is understandable after spending almost $15 billion for preparations for the Games, and the cancellation of the event means the huge investments have gone waste.
However, the pressure for the cancellation or postponement of the event have become intense after Australia and Canada on Monday announced that they were not going to send athletes to the Games due to the ongoing outbreak.
For the two countries who have also been hard hit by the pandemic, participating in the Games would pose more threat to the campaign against the global pandemic, as they can also not guarantee the safety of their athletes.
In addition, the pandemic seemed to have affected the qualifiers for the competition as most athletes are yet to secure qualification marks to participate in the Games. Boxers from Europe and Asia are yet to undertake their qualifiers, which the world qualifiers in France in May also hanged up due to the pandemic.
Similarly, the training schedules of most athletes for the games have been truncated following the pandemic and this has made the call for the postponement of the Games more intense.
It is expected that many countries would announce their withdrawal from the competition, thereby making the competition less attractive and meeting the Olympic values.
With no end in sight for the virus, as daily reports suggests a decrease in the number of people infected as well as deaths, one cannot but say the 2020 Olympic Games is in serious doubts.


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United Kingdom
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This course will help both new and more experienced line managers prepare for and run successful performance appraisals and increase their confidence in supporting, challenging and developing staff.
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Afterthoughts on the asian crisis
More information
Category: Jamaican
Comparative Economic Studies. The Peruvian central bank took two major decisions in the early s: implementing an inflation target system and accumulating sufficient foreign-exchange reserves. These two decisions have allowed the central bank to preserve macroeconomic stability in favorable or unfavorable international environments. The use and impact of the main monetary policy instruments over the period — is discussed, namely, the short-term interest rate set by the central bank or reference interest rate, the reserve requirement ratio in local and foreign currencies, and, finally, sterilized intervention in the foreign exchange market. The process of bank credit de dollarization is also reviewed. Skip to main content.
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The Asian financial crisis, like many other financial crises before and after it, began with a series of asset bubbles. Growth in the region's export economies led to high levels of foreign direct investment , which in turn led to soaring real estate values, bolder corporate spending, and even large public infrastructure projects. Heavy borrowing from banks provided most of the funding. Ready investors and easy lending often lead to reduced investment quality, and excess capacity soon began to show in these economies.
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This paper is concerned with the role of debt composition on the firm-level investment by raising a main question: whether firms with high foreign currency or short maturity debts have less investment following a financial crisis. This paper finds that firms with more dollar debt have significantly less investment due to exchange rate depreciations. Accordingly, the balance sheet effects of exchange rate devaluations undermine the competitiveness of listed firms in Indonesia, so that the effects of crisis have been exacerbated and prolonged through corporate balance sheet channel.
The Asian financial crisis was a period of financial crisis that gripped much of East Asia and Southeast Asia beginning in July and raised fears of a worldwide economic meltdown due to financial contagion. Capital flight ensued, beginning an international chain reaction. At the time, Thailand had acquired a burden of foreign debt that made the country effectively bankrupt even before the collapse of its currency.
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- Promotional prices apply until the 7th of February 2020. From the 8th of February, standard prices for 2020 will apply.
- This promo can be used for a maximum of 4 weeks, after this time standard prices for 2020 will apply;
- To confirm the booking, we require the payment of the booking fee and one week rent, both not refundable;
- Rent must be paid in advance and it is not refundable;
- Full Security Deposit is required (by Credit Card) and it will be refunded at check-out, provided that everything is clean and in the same conditions as at the time of the check-in (-€30 check-out fee);
- If you would like to extend your stay from the 5th week, normal prices will be applied;
- Please note that it is possible to book extra nights after the promotion expiries but these should be paid for separately, at a standard price;
- This offer is subject to availability;
- Meeting at the property between 9am and 6pm; before 9am and after 6pm self-check in only;


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Watch Nov 18 Regular Council Meeting: Owner appeals Tin Grotto remediation order
–Highlights, Sooke Council meeting Nov 18 2019
Watch Sooke Council deliberate the tin grotto (2076 Otter Point Road) owner's appeal of an earlier decision to remediate the building. (Video will start at the beginning of this discussion.)
The current owner notes the significant clean-up that has already been undertaken. Council ultimately opted to support its original action but to extend the timeline for an additional 30 days. The building is for sale. If the District demolishes it, the costs will be assigned to the owner of the building.
Supporting documentation
Video clip
Date: Nov 18, 2019
Duration: Item runs from about the 4-minute mark to the 45-minute mark.
Present: Mayor Maja Tait and Councillors Tony St-Pierre, Megan McMath, Al Beddows, Jeff Bateman, Dana LaJeunesse, and Ebony Logins. Guest speaker Mr. Denis Woodward.


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Early Bird Restaurant
37 Main St, Oakland, ME, 04963
Early Bird Restaurant Menu
Sorry, We are updating this restaurant menu details.
Visit below restaurant in Oakland for healthy meals suggestion.
Visit below restaurant in Oakland for healthy meals suggestion.
Sorry, We are updating this restaurant cholesterol menu details.
Anne S.
The Crowd: mostly locals, the occasional colby/thomas college student who is tired of the dining halls. The Food: dirt cheap eggs, pancakes, what have you, all of decent quality. The baked goods are pretty good and, frankly, it's the best meal you can find at 4:45 a.m. in the oakland/waterville area. Note: all juices- including the "fresh" oj- are from mixes. The Atmosphere: clean but pretty low key- what do you want from a place that charges about two bucks for a stack of pancakes? The Bottom Line: not bad. Cheap, good, quick food: not much to complain about. Parking is easy and ample. Great for a hungover brunch.
Shannon G.
Oh my. Early Bird knows how to do breakfast. Came here this past weekend on a visit to Maine and ate like kings. It was crazy packed on a Sunday morning (always a good sign) but we were seated in 15 minutes, no hassle. We ordered the grilled pumpkin muffin, cinnamon roll, fried eggs, hash browns, ham, bacon... everything we could stomach! And for so, so cheap. It was all delicious. I'm salivating just thinking about that pumpkin muffin and those hash browns. Will definitely be trying the ginormous pancakes next time!
Shanna D.
One of my favorite places to go for breakfast. Fairly priced and the service is good and fast!
Lou V.
This place is solid Americana. Honorable greasy spoon. The food is basic and well made. Nothing fancy or foodie. I come hear every summer when I bring my son to camp. The wait staff are hard working and honest.
Adam L.
I've been going to this place for family breakfasts since I was young. The serving sizes are fairly large, so you're getting what you pay for. That almost is a negative, though, because I usually want to order a plethora of food, knowing that if I do, most of it will go to waste. It's best to go with some friends (or family), buy everything you want, and split it. When I go, I usually get some sort of egg omelet, a muffin (get it grilled--trust me), some hash browns, and chocolate milk. It's somewhat of a tradition, I think. Definitely give this place a try.
Kenneth G.
This restaurant came up fast and furious. Besides serving fantastic foods, especially breakfast, the politics are huge. Yet price is not. If you order their pancakes and gripe about only getting two, wait until you see the two first. They are each the size of a dinner plate. Freshest of all ingredients, great lunches, too. I've always find for breakfast and always had at hard time getting a parking spot and seat. It's that popular. Lines move fast, so never a long wait and it's worth working for.
Bob W.
Five stars for the Early Bird! Classic Maine breakfast joint. Delicious food, generous portions, friendly servers. The muffins are a must. Here's how you know these guys know their shit. When you order a muffin grilled, they slice it into three pieces, not just two, without us even asking them to do so. The egg dishes are always excellent, and my hash-loving brother gives the Early Bird's a thumbs-up. The clientele is mostly locals, but people from away like us are always treated very nicely. Breakfast is the best meal in Maine, so we set the bar high, and these guys clear it with ease.
Reid F.
A terrific place for breakfast and local flavor. Just remember to bring cash.
Linda M.
We were in town for Parent's weekend....I agree - if you are in the area for lunch or breakfast, do try it out! The portions were good and not greasey and the wait was worth it. The atmosphere is cheerful and very simple...very. Prices are outrageously reasonable
Charles W.
Open from 5:30am-2:00pm. Great breakfasts and the hot chicken sandwich with gravy is incredible. Supposedly everything is made there including the bread. The best part is that the portions are huge. Worth checking out if you're in the area. Always packed with locals.
Kristen H.
My bf got a burger and fries. He said it was okay. I got the chicken burger with swiss. I liked it. Chicken was yummy and the Swiss melty. The service was great! So it's a breakfast lunch joint, nothing spectacular but hit the spot in a pinch.
Kate N.
Cash only, be ready to wait. You could eat for days on your one meal. So affordable. You just can't go wrong!
Melissa B.
I'm deducting a star because this establishment is cash-only (seriously, it's 2014) and the menu I was handed was physically nasty-dirty. Other than that, the food was very good. I ordered the eggs benedict, and the english muffin was crispy and perfect, the eggs were poached perfectly and the hollandaise was tasty, however, there was so much hollandaise on the plate that the muffin quickly became soggy, which was disappointing. It should top the eggs, not be the main component of the dish. My boyfriend got the sausage gravy and biscuit, which I thought was just average (I could make it at home). The portions were large. The coffee was pretty terrible though, but I don't go to a place like this for good coffee.
Paula H.
I have only been for breakfast and it always seems busy. I thought the food was good and the price was even better. Cash only is one drawback.
Randy H.
The portions are really huge. Great home style meals. Very simple cute decor with friendly and quick service. Note early open and closing times.
Phillip A.
CASH ONLY!!! Was unprepared and had to run over to ATM when I got my bill!! but overall a pretty good breakfast with just the right portions and fast too. Um did I say CASH ONLY!!, hard to believe that there are still places like this but when in Maine.....
Sorry, we don't have Q&A for this restaurant.
Sorry, No Coupons available for this restaurant.
Opening Hours
Sorry, Store hours have not been updated. If you are the owner of this restaurants. Please update the store hours.
- Takes Reservations : No
Delivery : No
Take-out : Yes
Accepts Credit Cards : No
Good For : Breakfast
Parking : Private Lot
Wheelchair Accessible : Yes
Good for Kids : Yes
Good for Groups : Yes
Attire : Casual
Ambience : Divey
Noise Level : Loud
Alcohol : No
Outdoor Seating : No
Wi-Fi : No
Has TV : No
Waiter Service : Yes
Caters : No
© 2020 Restaurant Listings. All rights reserved.


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In part one of this presentation, physicist Eugene Bagashov began his examination of some of the enduring geological mysteries on Mars.
Of course, geologists examining the surface of Mars project familiar earthly processes onto the Red Planet — they imagine volcanic eruptions, flowing water and impacts from space as dominant forces shaping the Martian landscape. But countless Martian features defy these explanations.
Proponents of the Electric Universe theory have proposed that another process, high energy electrical discharge, may have produced some of the dramatic features on Mars — a hypothesis with a growing body of experimental support.
In this conclusion, Eugene summarizes some of the most compelling evidence for electrical scarring on Mars and elsewhere in the solar system, including our own planet.
Part one of the presentation:
Featured image and videos courtesy The Thunderbolts Project
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Your weekend survival guide
Here's a little "Weekend Survival Guide" – designed to help your healthy eating plan survive those dreaded weekends: Plan family activities like bike rides or outdoor games. This helps you spend time with your family and burn calories at the same time! Carry a water bottle with you to your weekend activities. This will help you get your water for the day and resist…Read More
Interval Training
Interval training is alternating bursts of intense activity with intervals of lighter activity. For example, if you walk for exercise and you're in fairly good shape, you might incorporate 30 seconds of jogging with 1-3 minutes of walking, and continually repeat. If you haven't worked up to jogging yet, you might alternate a moderate walking…Read More
Intensity or Insanity
QUESTION: Do you think that the intensity of your workout is "THE THING" that gives you results or is it more about being consistent with your workouts? I like doing these kind of workouts, but I'm having a hard time pushing myself that hard every day and I'm finding now that I'm starting to dread doing…Read More
How to be a successful maintainer
MY TOP 5 TIPS TO BE A SUCCESSFUL MAINTAINER 1. Increase your total daily activity level, including formal exercise as well as sports, physical work or recreational activity. Exercise improves weight loss, but more importantly, it is critical for weight maintenance. 2. Decrease sedentary recreational activities by cutting back on TV watching, computer games and…Read More
The ups and downs of a bodybuilder's journey
It was a few years ago when i decided to grace the stage after just turning 50 it was a long life quest to hold a title of Mr Australia in my division,not only did I do that I ended up winning the Mr Australia Asia and here are a few tips I learn't on…Read More


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I've been looking through the Ark Clothing site and have found all sorts of beautiful things I'd love to be wearing. My focus has been so much on holiday stuff recently that I'd forgotten all about amazing patterned leggings like the day of the dead ones in the bottom right above. I need to wear these with a simple top and massive boots. Also, the leather-sleeved military jacket in the top row is exactly what I've been looking for. Although, it's not really practical considering it's (supposed to be) summer.
There's a big sale going on at the moment so there's a good chance you'll be able to find a bargain! How about a cheap GEEK t-shirt. This one is only £3.50.