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Cerebellar Abiotrophy (CA) , A Serious Concern
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[quote][i]Originally posted by Montana[/i] [br]Hi folks! A couple of things for those of you who are most interested in this topic. I consulted with Dr. Alexander de LaHunta, a retired verterinary neurologist from Cornell University, about my filly. He told me a few interesting things. One is that the loss of of the purkinje cells the allow the granular and cortical layer of the cerebellum to communicate (which is basically what CA is...loss of purkinje cells...that's what they look for in an autopsy) will occur for about 6 to 12 months from onset but then stop and the horse will stabilize--if it lives that long and if the symptoms are not so severe that the horse is at risk of killing itself in an accident and needs to be euthanized for humane reasons! This is true from my experience with my filly May. Severity of symptoms varies tremendously. She first had noticable symptoms as a yearling (though may have had symptoms that were not noticed sooner--she has a relatively mild case) and while it was so upsetting to see her repeatedly fall down and run into fences that I nearly put her down, my vet kept talking me out of it [:P] and so I did notice what appeared to be an "improvement" over time...she didn't get better, but she DID learn to cognitively compensate for the fact that her cerebellum didn't fully communicate with the rest of her brain. She's now four. The bottom line on bloodlines is that the suspect lines exist all over: in Crabbet, Polish, Russian, and Spanish breeding. (I think there have been cases in Egyptian lines, but I have no direct examples--however, the Egyptian lines have their own problems with Lavender foal syndrome and juvenile epilepsy anyway) So, no matter what horses turn out to be the progenitors, all the likely suspects are probably in 90-99% of all Arabian pedigrees today. I also agree with Lisa that in places where the gene pool gets smaller, the prevalence is going to rise. We must have a test because we simply cannot eliminate the suspect lines. We might on occasion be able to pinpoint a carrier, but even when you breed a carrier to a carrier, you have a 25% chance of a "clear" foal, and thus it is also important not to scapegoat a particular line. For example, I am virtually certain that a particular horse foaled prior to 1950 was a carrier. However, although people have helped me identify several of his sons and grandsons who are carriers too--they threw affected foals (including my filly)--I am also reasonably sure that his most famous son is probably NOT a carrier. So, we have a dilemma: Without a test, we don't know who the carriers are until they produce an affected foal. But if we eliminate a bloodline without knowing if a horse is a carrier for sure, we risk throwing out the good with the bad. I urge everyone to support Lisa's efforts and provide all the data you can. In the states, "wobblers" is a catchall term for horses with neurological problems. Any Arabian with neurological symptoms probably does NOT have true "wobbler's syndrome," but rather has CA or another genetic condition we know even less about called OAAM (occipital-atlantal-axial-myelopathy). What IS important to remember is that this is a recessive condition, so it can "lurk" for generations, passed on as a carrier gene and yet a horse in between never throwing an affected offspring (this is particularly true of mares, even the most productive have relatively few foals compared to a stallion). In the case of my filly, a full sibling died mysteriously as a suckling...a massive onset of CA? We don't know, the breeders claim they found the foal dead in its stall one morning and the local agriculture college (no vet school) couldn't determine a cause of death--but didn't autopsy the brain! Other than that, May's sire has not, to my knowledge, sired other affected foals. But, it only takes one to identify a carrier. "Prepotency" has no effect...it's a flip of the coin, a 50-50 chance the carrier horse will pass on the gene every time (and, an affected foal will only occur if the horse is bred to another carrier who happens to pass on the gene as well). In the total population, of random matings of carriers and non-carriers, the incidence will be about 3%. But if the gene pool shrinks, that incidence will rise. For example, there is documentation in the veterinary literature of a farm that closely bred certain bloodlines lost 8% of its foal crop to CA in a single year! So, I encourage a twofold approach: 1) Education of veterinarians to recognize the disease when it appears; 2) Helping researchers obtain enough DNA samples to develop a test. To do this, we need owners who both recognize the condition and understand that it is to everyone's benefit to provide this critially needed data. Sorry to go on so long about this, but the condition was first observed in the veterinary literature in 1966. I think 40+ years is plenty of time to educate vets and owners about the disease, and now that we have the technology, it's time to develop a test! Thank you, everyone, for your interest and caring. [/quote]
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Posted - 12 Jan 2007 : 8:16:38 PM
CA is a defective genetic allele appearing in ALL Arabian Bloodlines. Please Read~
25 L A T E S T R E P L I E S (Newest First)
Posted - 17 Dec 2013 : 10:38:41 PM
Just wanted to share these links to remind everyone about CA and the importance of testing. They show the most beautiful little colt who unfortunately is no longer with us. Hopefully these videos will help show how important it is to be aware of CA and test. He really had the most beautiful head and such a profoundly deep and sad look in his eye. Even in his short life he was special.
Brigid Fairman
Posted - 02 Oct 2012 : 6:04:01 PM
I find this thread very interesting as I owned an endurance horse who would suddenly lose co-ordination and fall down. He would also go disunited in canter. The episodes were very brief and he would immediately spring to his feet. I had him looked at by Sue Dyson at the Animal Health Trust but her findings were inconclusive. Watching him suddenly collapse while being lunged made up my mind for me never to ride him again. He eventually broke a leg in the field and was put down.
Posted - 10 Aug 2011 : 12:38:16 PM
Newly posted Test Lab in the UK.
ANIMAL GENETICS in Cornwall:
Also we have a professional webmaster in charge now and the CA Public Lists have been condenced into ONE Alphabetisized Public List. So much easier to search for horses now.
Posted - 12 Mar 2011 : 4:28:21 PM
The laboratory of the Netherlands @ Dr. Van Haeringen Laboratorium (VGL)is now offerring in-house testing with the new CA test at very reasonable prices:
�42.50 = US$59.08, �40.00 = US$55.61, �15.00 = US$20.85, �70.00 = US$97.32. (current exchange rate 12Mar2011)
- CA ONLY @ 42.50� (single samples)
- SCID ONLY @ 40.00� (single samples)
- LFS ONLY @ 40.00� (single samples)
- Optional ADD DNA-Profile @ + 15.00� (single samples)
- COMBO: CA + SCID + LFS + DNA-Profile @70.00�
Click HERE
for the information flyer
The test can be done on hair roots or blood. Please send in the material and a sample submission form, which you can print out from our website. ("Genetic properties') If you cannot print them please let us know and we will send some sample submission forms by post. You do not need an import permit within the European Union.
Dr. Van Haeringen Laboratorium BV
P.O. Box 408
6700 AK Wageningen
Tel +31 317 416 402
Fax +31 317 426 117
Posted - 10 Jan 2011 : 2:06:22 PM
For any of you who have been concerned about the validity of the CA Marker Scanning test please go to the CA WEBsite for the latest NEWS!
The Causative Mutation has been identified at UC Davis �s VGL lab.
This is really exciting news and soon there will be more to come!
Posted - 02 Dec 2010 : 11:29:32 PM
Thanks, Lisa. I assumed that it was just a random thing as I have occasionally seen my new foals get up back end first and never thought any more about it and, as you say, the birth is down to mum.
Posted - 02 Dec 2010 : 02:46:37 AM
As we all know too well, new born foals have a pretty wobbly time of it when trying to get to their feet. I have seen perfectly normal foals use their muzzle to support themselves as they try to stand.
A CA Affected foal is going to have a difficult time trying not to run into things once it is on its legs. The most noticable clinical sign of CA is the head tremors.
As for the protracted birth , that is more of a problem of the mare�s, not the foal�s condition. The mare is the one trying to push the foal out. The foal is just going along with the whole proceedure.
Posted - 01 Dec 2010 : 10:07:14 PM
I have just been rereading this thread and I noticed that an affected foal had "a protracted birth and took a long time to stand. it also stood at the back end first rather than at the front". Is this usual in CA affected foals and is standing with the rear end first indicative of CA in the newborn as I understood from the literature that CA foals were normal for weeks/months after birth and only developed symptoms as the purkinge cells died off rather than developed?
Posted - 23 Oct 2010 : 4:10:40 PM
The latest statistics are in
This week we received the latest statistics from UC Davis. Nothing changed much from the previous information, which means that the carrier percentage remains the same, just under 20%.
Disclosures of carriers and clears on the CA website also stayed steady at ~ 12% and 86% respectively. These numbers vary strongly from those of UC Davis, but logically owners are swifter to disclose a clear rather than a carrier.
For the complete overview go to the statistics page.
Posted - 28 Sep 2010 : 11:43:25 PM
I am delighted to see that the AUSTRALIAN REGISTRY IS LEADING THE WAY IN ARABIAN HORSE GENETIC DISEASES !!!!!!!!!!!!!!!!
The above is based on the September Bulletin of the AHSA:
1st January 2011 is the cut off date.
- No imported breeding stock will be allowed to be registered unless DNA results of tests for SCID, CA and LFS are presented to the AHSA.
- No imported semen will be allowed for use unless AHSA has receipt of DNA tests for SCID, CA and LFS.
- The Board is also actively investigating the testing of ALL nominated stallions for SCID, CA, LFS and GPA (as tests become available) with the intention of publishing the results on the online Stud Book.
The CA WEB has this information also on the Latest News Page:
Posted - 18 Apr 2010 : 04:02:05 AM
Now on the heels of the Swiss Registry accepting compulsorary testing for CA , we
have Saturday�s results in on:
VZAP (German Arabian Registry)
German to English translation
Results of the Annual General Meeting:
All breeding horses, whether new or old, mare or stallion must be tested.
Breeding animals that are re-recorded must be tested immediately, the "old" have a transitional measure until 31.12.2011.
There were no abstentions - so there were all members present 100% for the tests.
The already made tests are accepted in full.
Hopefully this will give other registries an incentive to do the same.!
Posted - 09 Apr 2010 : 3:42:30 PM
I have heard from Dr, Penedo and LABOKLIN (UK) is also working in conjuction with UC Davis to do the CA testing. Same link as above and use their contact email to get more information.
Posted - 15 Mar 2010 : 12:30:33 PM
There have been some changes at the CA website
Due to the amount of entries and space available on even this excellent band width, the CA Status List has been redesigned into two sections:
MAIN LIST with all entries posted in the order received: Horse Name + Identification + Status
CARRIER /AFFECTED LIST in alphabetical order with Horse Name + Identification + Status.
SEARCH OPTIONS remain the same on both pages:
- Use search box provided at top of each page for a page search.
- Right click on entry without number and do a Google Search. This usually brings up website / farm name / owner or breeder info.
Please note the following important additions:
Only owners of horses have the option to submit and publish two default CA derivatives under their own responsibility:
- "CA: Clear by parentage" - for a foal of which both parents are tested CA N/N CLEAR
- "CA: CARRIER by default (I)" - for a parent of a CA: CA/CA AFFECTED foal
- "CA: CARRIER by default (II)" - for a parent of a CA: N/CA CARRIER foal of which the other parent is CA: N/N CLEAR
The CA Marker Scanning Test was officially launched in September 2008. Horses tested by this method and those horses clinically diagnosed with a necropsy prior to this date are designated by the symbols N/N Clear, N/CA CARRIER or CA/CA AFFECTED where applicable. Horses which were vet diagnosed based on clinical signs but not clinically diagnosed with a post mortum microscopic study (Histopathic) are termed simply AFFECTED.
Thank you,
Posted - 03 Mar 2010 : 8:50:07 PM
Good to see, Pinto
If the CA site is going to be a complete database there will be quite a few people Worldwide affected by the difficulties in posting colours so I guess they will want to change that.
Given that he is chestnut, even I managed to navigate the site to post that Marcus Aurelius is CA in addition to SCID clear
Posted - 02 Mar 2010 : 9:05:17 PM
CA results for our gang in today:
Picasso Kossack (Kubinec x Popova) CA clear.SCID clear.
Rodania Karisma (Farrukh x Kadidja) CA Clear.SCID test pending.
Prima Ballerina (Thee Onyx x LC Special Treat)CA Clear.SCID clear.
Malibu Surfbreaker (Kennox Zalsun x Mistral Whisper)CA Clear.SCID clear.
TP Starbuck (Black Tie x TP Mystic Fire) CA Clear.SCID clear.
Incandescent Flame (TP Starbuck x Malibu Surfbreaker CA Clear.SCID clear (both parents tested clear).
AKA Starbuck's Champagne Star (TP Starbuck x Malibu Surfbreaker) CA Clear.SCID clear (both parents tested clear).
Roundhills Crystal King (Moonshine Vision x Shulay Coral) CA clear. SCID clear.
It's Showtyme (Infiniti Z x Hunter's Moon) CA clear. SCID clear.
Having a problem posting results for the part breds on the CA site as their colours aren't recognised and colour is a required field.
Posted - 09 Feb 2010 : 11:42:24 PM
I am very pleased to be able to say that Pianist(Gazal al Shaqab x HS Pelagrina) has just tested N/N clear for CA.Still awaiting scid results.
Just had his Scid result back.Scid clear.
Posted - 04 Feb 2010 : 2:12:00 PM
Congratulations ! That is great news. Be sure to share it and submit your test results to the CA Website:
Originally posted by JuliaB
Just had the CA result back on my daughter, Olivia's, 2 year old colt Phantom (Azteq x Pjatakova) which is clear (N/N). To say we are pleased is an understatement.
Posted - 04 Feb 2010 : 09:22:04 AM
Just had the CA result back on my daughter, Olivia's, 2 year old colt Phantom (Azteq x Pjatakova) which is clear (N/N). To say we are pleased is an understatement.
Posted - 03 Feb 2010 : 10:43:03 PM
I have emailed Trina our webmaster and my sincerst apologies for the mistake. As part of the CA website team , as stated on the Public List:
Owners or agents of the following horses have disclosed their results publicly on websites, public forums, equine journals or given permission privately. Any information unintentionally or otherwise wrongly posted will be removed with-in 48 hours upon request of owner or authorized agent.
Our team consists of myself , Trina the webmaster (and owner of an affected foal) and Gideon who most generously donated the website domain for us. Trina is on the far side of the US so the time difference sometimes is a handicap but I assure you she will correct it as soon as possible.
Again my sincerest apologies for the mistake of typying SCID clear instead of a SCID carrier
Posted - 03 Feb 2010 : 9:50:20 PM
Just a little request:
Yesterday (2/2/09) I posted our first 4 results on one of the CA threads, before submitting them to the CA website.
Today I checked the international list. Someone had posted our results there before my own submission (described as "on arabianlines.com" in the header - which means how the information was gathered).
Now that's not a problem, except that the person who posted the results got them wrong.
One of the boys is a SCID carrier, incorrectly copied by whoever as clear - see my postings on the CA threads. I would hate anyone to think we were trying to cover up a carrier status, and I hope that I have corrected the error (resubmitted to the CA site and I hope they won't just look at it and say: "weve already got him...")
I suggest that people don't rush in to submit other peoples' results. We don't need an assumption that the owners will try to deceive us: that's paranoia. If you do submit under a sort of freedom of information flag, GET IT RIGHT.
Seren Arabians
Posted - 02 Feb 2010 : 6:47:44 PM
This morning we received the first 4 results. The original set of samples didn't arrive in Holland, hence the forever wait...
UC Davis emailed on Thursday that they had received the samples, and the results arrived at 0200 GMT Tuesday (or about 1800 local time on Monday in California. That's faster than their most optimistic published turnround of 5 working days.
Winged Saint: SCID clear and now CA clear
Halal: SCID carrier and now CA clear
Seren Hanau: SCID clear and now CA clear
seren Hanag: SCID clear and now CA clear
Posted - 01 Feb 2010 : 11:34:24 PM
G.Fantastica (IBN Estopa x Fanatica) Tested UC Davis
CA clear
Posted - 12 Jan 2010 : 8:36:01 PM
MONESCOCIA (Ajman Moniscione x Estoniah) CA & SCID CLEAR .
Posted - 08 Jan 2010 : 03:05:53 AM
The CA website has moved to a new server with a broader band so we now have faster downloading :
We are also pleased to say that over 500 entries have been made on the CA Status List.
Including a first time result from a deceased stallion by using frozen semen.
Our applause to Rojo Arabians for their support and efforts with VERSACE !!
And his dam!
Check it out.
Register to get the latest updates.
Posted - 30 Dec 2009 : 4:23:38 PM
Yes, Lisa, I'm now of the opinion that I haven't wasted the fee for the tests I have submitted. I'm also waiting for replies from UC Davis which may convince me to start the testing of the other 15 as well.
I note that the VH site is still carrying the same doubt-producing information about the test, and their terms and conditions section 7 gives them the usual walk-away from the consequences if the test had turned out to be based on wishful thinking.
I make no apologies for asking the questions and raising my doubts. The resistance I have encountered in bringing other dog breeders on board as far as genetic testing is concerned has taught me that people need the clearest explanation available.
Once I am completely happy with the reliability of the testing, we will make the same offer to other breeders as we already do with the dogs: as well as offering clear stallions to carrier mare owners, we will also offer carrier stallion owners the opportunity to bring their stallions here to our clear mares to rescue their lines. (Note the optimistic assumption here!)
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Wild Stories About The Spice Girls That Prove They Are The Definition Of Girl Power
It feels like every couple years the Spice Girls are rumored to be embarking on a reunion tour, much to the excitement of their worldwide fan base. The girl group that took over the '90s pop scene remains hugely popular, but there may still be some things you didn't know about the Spice Girls.
By 1996, Baby, Ginger, Posh, Scary, and Sporty Spice conquered England and then went on to conquer the world. Their debut single "Wannabe" was a huge success that still holds up over a decade later, not only because of its pop beat and catchy lyrics, but also because fans are likely still trying to figure out what the heck "zig-a-zig-ah" even means. More hits followed and the girls reached undeniable stardom. They released their very own (insane) movie, Spice World, and rubbed shoulders with powerful world leaders, all while maintaining their signature cheeky attitude. Wild stories about the Spice Girls include their bold questions of royalty ("Do you have a Prince Albert?") and unconventional ways of celebrating (let's hope Posh got her knickers back).
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That inquiry from Baby Spice sure showed she had girl power and, well… balls.
From the beginning of their career, the Spice Girls got the opportunity to hang out with some powerful, important people... and yet never seemed intimidated. They even got to meet South African leader Nelson Mandela at his home, and the girls weren't afraid of nabbing some souvenirs. During the visit, Ginger, Baby, and Scary Spice took some toilet paper and pebbles from a plant in the Mandela bathroom.
"I told Nelson what I'd done and he just laughed," Scary Spice said.
Getting signed to a record label is a huge deal for a recording artist new to the music scene and is without question a reason to celebrate. A normal celebration might include a small party for friends with a champagne toast, or maybe a commemorative photo shoot. The Spice Girls don't do many things normally, though.
In her memoir Learning to Fly, Victoria Beckham (Posh Spice) reveals what happened when the girls got the exciting news: "I was so drunk I fell over and the other girls ripped my knickers off and threw them out of the window," she said. "I have a vague memory of hanging out of the window and shouting to the world, 'We've just signed with Virgin!'"
When Prince Charles attended the premiere of the group's movie Spice World in December 1997, the Spice Girls again caused a stir with their interactions with the royal. Ginger and Scary Spice kissed the Prince on the cheek, breaking strict royal family rules. Even more shocking, though, was when Ginger Spice allegedly pinched Charles on the bum.
In 2016, however, she set the record straight: "I didn't pinch Prince Charles's bum, as was reported. I patted it." She explained, "Patting him on the bottom was against royal protocol, but we're all human. It was the premiere of our film, Spice World, in the late '90s. There was a lot of nervous energy – young women, happy antics."
Prince Charles should learn stay away from these fearless girls if he wants to stay out of trouble.

subset: commoncrawl


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Using Dex3 v3 10.0.4 The Mouse arrow wont scroll in main list or under my userlists or database or history. The Side list on the right scrolls up and down ok using the muse. Its like the arrow is stuck and wont move the list up not down. I can use the mouse wheel and it will scroll up and down the list. Many thanks. Steve.
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Try searching this forum. I'm sure the information will be there somewhere. Th H of G is under some boxes in a room offff the swimming pool (I think).
Where can I find the "Hand of Glory" and the "Keeper's Medallion"?
And I have also to find 800 in Gold. Where is it?
Thank you.
Try searching this forum. I'm sure the information will be there somewhere. Th H of G is under some boxes in a room offff the swimming pool (I think).
Philly's is right. The Hand of Glory is in one of the rooms just off of the big pool. It's the room across from the Sergeant at Arms room. Move the boxes.
The Medalllion is a little more complicated to explain. You need to go back to the pool that you swam up out of to get to the area with the bank. There was a locked gate on the other side that you couldn't go through. Hopefully, it's open now. (Did you find the key to the Gate room and go back and flip the lever?) Go upstairs in the building in there and look for a ceiling hatch over a water trough. The Medallion is in the area up there. There's loot in that area as well, so that may be enough.
Where can I open the locked door next to the bank? Where is the key and the lever?
Which locked door next to the bank?? There are some doors that don't open at all in this mission. I've smashed a wood one down in the bank area and there's nothing behind it. Is that the door that you mean?
I think the Gate room key is found in the other building down by the Bank, the same building where you found the vault key. The Gate room itself is in the building that you enter by rope arrowing up onto a balcony. After you go up on the balcony, go out to the hall and downstairs. The Gate room is down there and the lever in there opens the gate to the area with the Medallion.
Neat mission. Recent addition to cheap mission downloads. The objectives unfold as you play, not spelled out beforehand. You start with nothing, and only 3 health points. And if one of the guards sees you, game over.
Anyway, where's the switch to open the gate? (I'm probably standing on it, or looking right at it.) Thx V6
spoiler:The switch is inside a building very close to where you come up out of the crypt. It's ahead and a bit to the right as you walk out that door.
This mission pack ended on me prematurely. I was in the 3rd mission and went down into the crypt and I got the Mission Complete screen, even though I hadn't completed the objectives. I never saved and the strangeness of this mission pack left me with no motivation to restart. There seems to be alot of storyline that's missing.
Hmmm , I can't get this one to end . I went through the gate and even checked out the underground gate . Interesting concept though .
Last edited by bdkl; 25th Jun 2002 at 20:18.
I have everything but the eye.
I have a bunch of keys and have been everywhere I can think of and just can't seem to find it.
Help me, hint me, spoil me, anything, I am getting tired of looking at the scenery.
Also can you get in the bank where the teller is?...don't tell me ..... thats where the eye is, right?
Try searching for "Awaken" down at the bottom right of the main page of this forum
I did try the search but didn't see anything about the eye. I saw a lot about the hand of glory but not the eye
You're talking about The Awakenings, right? Awaken is a different mission but I don't recall a bank in it. In Awakenings, the bank key is in the building to the south past the Bank door. There is a church upstairs, but the bank key is in the set of rooms to the left before you go up the stairs to the church itself. You also need another key, which you find upstairs in the rooms behind the church.
I can get in the bank but I can't get behind the counter and yes it is the awakening.
I have looked in the rooms behind the church alter and in the rooms that you get to going to the left of the bank and up the stairs if thats what you mean about behind the bank but I can't get to the stuff behind the wall inside the bank.
Help me!
You just climb over. Jump up on the desk, then over the railing above the counter and down onto the other side.
I don't know why I could not get over that wall before. I must have tried a hundred times but it worked this time. I was beginning to go crazy.
Anyway one more down.
has anyone completed this mission? i started the third part in the basement where i got the spices at the end of the previous section, avoided the guard, found the underground river and obtained the well cover key. then when i went back to the crypt the mission ended. i never got the key to the gate lever, yet that sole objective is checked off and i'm back to the main menu screen as if the entire mission in completed. what the deuce?
bdkl - how did you get through the gate and where is the underground gate (if you're not referring to the well cover)?
I have a question. After waking up in the crypt/tomb, and I leave it, I find myself not able to do much of anything. Found no items, equipment. Only a couple of hammers, including 1 in a room with other guys snoozing. What the heck do I do now? Any and all hints would be greatly appreciated.
You'll need to get inside the buildings so you'll need to pickpocket some keys.
"That I an accessary needs must be
To that sweet thief which sourly robs from me."
William Shakespeare, sonnet 35
Ok spamlet, I have i think 3 or 4 keys, and when I go into the tomb the mission ends. I dont believe I found a key for the lockbox to the gate lever. I managed to avoid the hammer in the storage room where you find herbs. After that I dont think I have done anything else.
So now what do I do? The hammers patrolling outside have no keys that I can see. The church/temple has hammers within and they kick the crap out of you if they find you. Not sure where to go from here.
thanks for the reply. any help from anybody is greatly appreciated.
i have had the same happen to me, get a couple of keys, avoid a guard, get spices, then go back to the crypt and that is all she wrote. Never once got to unlock the gate and run to the hills. What to do? Anybody have ideas?
I don't know if anyone is still interested, but I just gave this one a try and completed it. There wasn't much to do on the final mission. Just grab a key, outrun the guards, unlock the lever and throw it, then run out the gate. It was an interesting concept, but there wasn't much to it.
I have one key that gave me access to the small building with the gate lever and now I've run out of stuff to do There are no more keys to lift. What am I missing?
You're missing everything! You should be able to get into every building by the end of the mission (in other words, you aren't trying/looking hard enough). If you've been in the guard's sleeping quarters you should have another key. It's hard to see though so look carefully at the desk/counter areas.
It is also a mission which is split up into 3 sections though, so when you get through with 1st night's objective you go back down into the tomb. Did you go downstairs in the building with the gate lever yet? That might be part 2...?
"That I an accessary needs must be
To that sweet thief which sourly robs from me."
William Shakespeare, sonnet 35
Yeah, I went downstairs in that lever room, but my only key didn't open the door at the bottom. I will sweep those desks again and hopefully find another key.


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Raphe Nuclei
This page will be update by the 27th of Auj. Ninad Mehta
Basic Information
During the mid-nineteen century it was observed that the serum that was left after the clotting of the blood could constrict vascular smooth muscle so as to increase the vascular tone. It was later discovered that blood platelets were a source of this substance. Rapport and his collaborators[1] later isolated this compound and named it serotonin(5-hydrocytryptamine). Since the structure of 5-HT is hydrophilic and this would imply that I would not be able to pass through the blood-brain barrier and thus the presence of 5-HT in the blood suggested that it was produced in the brain. In 1964, Dahlstrom and Fuxe using the method of histoflurescence found that the majority of serotonergic soma was found in the midline of the brainstem. This locus had been designated as the raphe nuclei[2]. One fact that must be kept in mind is that not all the neurons in the raphe nuclei are serotonergic.
Traditional Dahlstrom and Fuxe described nine group of serotonin-containing cell bodies and they were designated B1 to B9. The figure shows the nine cell bodies and the region of the brain that they invigilate. The B1 to B4 are located in the midpons to caudal medulla. The largest group of serotonergic cells is the B7 . It is continuous with the B6 group of cells and they together from are called as the dorsal raphe nucleus. B8 is termed as median raphe nucleus(the nucleus central superior.) Group B9 is located in the ventrolateral tegmentum of the pons of the midbrain. The dorsal and the median raphe nuclei give rise to distinct projection in the forebrain region. Within this raphe the neurons are organized into groups that send axon to specific areas of the brain. The organized innervations of the fore brain structure by raphe neuron implies to the fact that the function of the neuron is dependent on their origin and terminal projection.
Some researchers use a different method of nomenclature for the Raphe nuclei. NeuroNames has shown a classification of the raphe nuclei into seven parts:-
Raphe nuclei of medulla:-
Nucleus raphe obscures Nucleus raphe magnus Nucleus pallidus.
Raphe nuclei of the pontine reticular formation
Pontine raphe nucleus Inferior central nucleus
Raphe nuclei of the Midbrain reticular formation
Superior central nucleus Dorsal Raphe nucleus
Specification of the Neuron
As mentioned earlier the total number of the serotonergic neurons is really small. In Rats the number of neurons is around 20,000 out of some 1010 neurons. The Neurons are generated in the early stages of embryonic development. It has been commonly observed that a day after the generation of the neurons they can start the production of 5-HT[3]. The raphe neurons also start profuse axon tracts and project into many parts of the brain and the spinal cord. Based on the labeled 5-HT uptake experiments and immunohistochemical techniques difference in the raphe nuclei neurons have been observed.
The axons of the neurons from the median raphe nucleus, type M, have coarse large spherical varicosities while the ones from the dorsal raphe, type D, have very fine and small pleomorphic varicosities.
The serotonergic neurons of the raphe nuclei exhibit spontaneous discharge activity of 1-5 spikes per second. [5] The activity of this neurons is controlled by three different events that take place in the nuclei. The events initially start of with the slow firing activity of 5-HT neurons, the autoinhibitry action of 5-HT and also by the signals provided by non-5-HT receptors. Both axon and Dendron's act as the site for the 5-HT release. [6]. The non-5-HT neurons in the raphe nuclei are GABA-containing interneurons. The function of this neurons is to establish local connection with the 5-HT neurons. It has been observed that GABA inhibits serotonergic system as it reduces the turn-over rate of 5-HT in the raphe nuclei. [7]
Molecular profile
- Neurotransmitter:Serotonin is a combination of the hydroxyl group in the 5 position of the indole nucleus and a primary amine nitrogen.[1] 5-HT is released from the serotonergic varicosities into the extra neuron place and not from the synaptic terminal boutons. The diffusion area of 5-HT is >20µm of the active receptor.[8]
- Receptor:The receptor for the serotonin are the same as the for 5-HT and they are located on the cell membrane of the neurons. Most of the 5-HT receptor in the neurons are G-proteins. When the ligand binds to this receptor it will activate and intracellular second messenger cascade. Seven classes of Receptor are know in case of mice. The information of the receptor is given in the table.
Serotonin plays an important role in the modulation of mood swings, anger, anxiety, aggression, body temperature, sleep, appetite, metabolism and sexuality. Serotonin is one of the major players in stimulating vomiting.
Researcher have found that mutation in the 5-HT2A receptor was much common in patients with major depression and suicidal tendencies. Studies on human patients groups have also shown that lower levels of serotonin leads to the shift of the behavior pattern to aggressiveness.
Gross and et al, have found that Serotonin 1A receptor acts during the development of a mice and leads to normal anxiety like behavior in adult mice. The knock – out of this receptor in these mice have shown higher levels of anxiety in the mice.[9] Groups of Researchers have also found that mice with defective serotonin receptors or 5-HT levels show deviations from the normal pattern of behavior in case of a maze experiment.
Serotonin has also been linked with SIDS ( sudden infant death syndrome). Lesurtel M. el al have shown that low levels of serotonin in mice brainstems that control heartbeat and breathing maybe one of the reasons for SIDS. Lately it has also been found that the serotonergic neurons in raphe have central respiratory chemoreceptos. It has also been proposed that the mid brain raphe neurons can sense the carbon dioxide. It is also believed that the raphe can induce anxiety, arousal or cerebrovascular modification so as to maintain the pH homeostasis.
- Author1 FM,Author2 FM (year) Title, Journal, vol: pages. PMID.
- Author1 FM,Author2 FM (year) Title, Journal, vol: pages. PMID.


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Job Description
The Mack Brooks Group are leading exhibition/trade fair organisers and publishers within a range of engineering, transport, textiles, trade and technical sectors, working internationally including in Europe, the USA and South-East Asia. Established in 1965 the company is privately owned, profitable and looking to expand its activities within media including exhibitions, publishing and the internet, by both new product and development and acquisition.
The Position
The company are currently looking for a PR & Marketing Executive who will be responsible for providing full administrative support as well as assisting with a variety of PR / Marketing activities relating to the preparation and staging of trade events. Additionally, Internal contact to exhibition teams and external contact to agencies and media companies as and when needed.
Key Tasks
- Creating content for HTML templates and delivering promotional email shots
- Copywriting promotional material
- Production of newsletters
- Assisting with the production of sales support material and website
- Database management
- Briefing designers
- Liaising with media companies
- Writing press releases
- Proof-reading of sales material and other documents
- Media buying and advertising campaigns
Skills, Knowledge, Experience
- Fluent German and English language skills (verbal & written communication)
- PR / Marketing experience, especially writing (open mindedness for dealing with technical jargon); media and customer service experience is seen as nice to have
- Professional MS Excel/Word skills; HTML and other mailing programs is seen as nice to have
- Hands-on individual with a strong administrative flair and an eye for design
- Proactive, well-organised, and independent style of work
- Highly accurate with a strong sense of responsibility
Qualifications /Commercial Experience
- A minimum of 1 years + commercial experience (not including internships)
The duties and responsibilities in this job description are intended to be indicative but not exhaustive of the responsibilities of the post holder. As Mack Brooks develops, the requirements of the job may develop and change. The post holder will be expected to adapt to these changes.
Mack Brooks is an equal opportunities employer.


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If you haven't already heard the official World Cup anthem, then you will do soon. There's a slight hiccup with Shakira's "Waka Waka" however – it's a copy of a 1980s classic from a group of Cameroonian presidential guards.
Since the Colombian popstar's song was selected by FIFA as the official anthem for the 2010 World Cup, African radio stations haven't stopped playing it. In Cameroon however, listeners soon realised that the tune was rather familiar. Even more so for the members of "Zangaleza", a pop group of presidential guards who came up with the song in the 1980s…
Shakira's Waka Waka:
The chorus is identical to that of the original - listen at 52" seconds. Video posted on YouTube by "edkalos".
The original song by Zangalewa:
Posted on YouTube by "SupraSensibilis".
"Zangalewa was a group of presidential guards who wrote the song for the troops"
Mohamadou Houmfa is a freelance journalist from Yaoundé, Cameroon.
Zangaleza say that they've come to an agreement with Shakira and will probably be compensated. But I think it's a shame that the international media don't point out where the song actually comes from.
The Cameroonians are actually very proud of the remake. In cybercafés you see both versions of the song playing on repeat. Young people don't know the original as it came out in 1986. [Zangalewa released four albums - the one that included the song in question was awarded 'record of the year' in Cameroon]. But the older generations know the clip off by heart, especially the bit with the presidential guards' parade. The song was released just after television arrived in the country so we remember it well.
Zangalewa [formed in 1984] was a group of presidential guards who wrote the song for the troops. They even sung part of the song in Beti, a dialect from the south.
This could prove to serve as an opportunity for the group who are talking about reforming now. It's also something positive for the Cameroonian players, who will be proud to think that the song comes from their country."


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If you are a regular attender of Danville Friends Church, we invite you be a part of the work God is doing through our weekly offering. You can place your tithes and offerings in the plate as it is passed or you can send a check to the church office.
Kroger Community Rewards
You can register your Kroger Plus Card with Danville Friends Church and a portion of your purchases at Kroger will be sent to our church.


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Don't miss out promotions, sales, and new product introductions!
These all-natural hand-dipped Milk Chocolate Cherry Truffles are created with old-world recipes and craftsmanship.We use only the finest chocolate, the freshest local cream, and the most flavorful Meduri fruits in these superb truffles. Montmorency Cherries create luscious "crumbles" blended into a delicate ganache center of milk chocolate that brings out the fruit's essence. It's a whole new way to enjoy chocolate covered fruits. Two truffles come packed in a sweet gift box. Find other unique specialty chocolate gifts at Meduri World Delights.
Coming Soon


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HensonFuerst Attorneys is proud to have sponsored the Stand Up! Anti-Bullying Festival, on Saturday, November 9, 2013. The event drew more than 2,500 people to the Royal Palace Theatre in Roanoke Rapids. The festival featured the Chris Hendricks Band, motivational speaker, Ahmed Toure and several other entertainers, vendors, and contests.
HensonFuerst is proud to sponsor Chris Hendricks Band's "Breaking Down Barriers" program in North Carolina schools. Chris Hendricks has cerebral palsy and was bullied throughout his childhood. His music and anti-bullying message motivate students to take action against bullying in their schools.
Chris Hendricks and David Henson discuss the importance of inspiring young people to help each other reach their fullest potential.
Our Anti-Bullying PSA Contest Video.
Performance Spotlight
Chris continually performs his message of Anti-Bullying. Did you know Chris was bullied too? Learn more about his inspirational story here:
Chris performs all around the North Carolina area. A few highlights are below.
StandUp! Anti-Bullying Festival
The Stand Up! Anti-Bullying Festival was a celebration of acceptance and spirit. More than 2,500 members of our community came together with the goal of raising awareness about the problem of bullying. It was a full day of music, entertainment, contests, vendors, and giveaways. We are honored to have been a part of it.
Durham Academy Middle School
The first Breaking Down Barriers program was a huge success! The program was held at Durham Academy Middle School, where Chris shared his story with nearly 400 students.


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Every design element in a little bathroom ought to have a purpose and be functional in some manner or another to create a space-saving sanctuary. These true-life small bathroom ideas are going to have you loving your space immediately. Perhaps, you've got an outdated second bathroom with a severe case of seventies style.
If storage is crucial, try out a wall-mounted floating vanity. Well-lit bathrooms feel bright and airy, therefore it's wise to benefit from pure light to make an illusion of room in your bathroom. Floor space could possibly be scarce in a compact bathroom, but it doesn't mean that you can't get the most out of your wall space.
If you should store a significant number of accessories and toiletries, then a little vanity with under counter cabinets is an option to think about. As soon as it's wonderful to believe that all grooming products can easily be kept behind cabinet doors, some bathrooms just don't permit that alternative. Vanity cabinets occupy a big room in your bathroom.
Small spaces are much more difficult to adjust and arrange, especially in regards to the bathroom. A bathroom redo may be a cheap and enjoyable method to spruce up your entire residence. It is a particular region of the house for private hygiene.
Just ensure you leave enough head clearance for those who stand up to visit the loo! You're probably wondering how someone can create a little bathroom to be functional and lovely. As the little bathroom above shows, including a mirror across a complete wall, can double the appearance and feel of a little room.
If you adore the vintage style, then do it. You are able to add an element of color in the shape of colorful parts of the accent in the restroom. You're able to add color to the entire wall or only a band of color.
The key isn't to squeeze too much in. You have to be worried about space, hygiene, and placement in a manner that suits your family's style but is also functional for ordinary use. Consider an overall look you would like to achieve and stick with this.


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You and I both know that big corporations use their massive amounts of cash to fight the kind of change we need in Washington. Unfortunately, it's about to get a lot worse. A recent decision by the Supreme Court lifted a century of modest limits on corporate spending in elections. Let's do something about it! Public Citizen has made it easy on a Web site you might find interesting: www.DontGetRolled.org.
Posted via email from #p


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Showing 11 posts from September 2019.
Mandated Reporting Age of Consent
An incident from Vermont illustrates a not-uncommon conundrum for mandated reporters, deciding when to report sexual activity by minors above the age of consent. The pastor of a church learned of consensual sexual activity between a minor in the church and the church's youth pastor. Because the girl was 16 year old, the age of consent in Vermont, the pastor's lawyer initially told him that he did not need to report it.
Reading, Writing, and … Mindfulness?
Two recently-published studies claim that mindfulness training can help children cope with stress in school. The first study was small, with only 99 middle-school children participating. Half of them received 8 weeks of mindfulness-based interventions, while the other half received active-control interventions.
Mandated Reporter: Sexting Laws
A recent court ruling continues the trend of insanity surrounding teenage sexting. A 16-year-old girl performed oral sex on a male friend, and one of them videoed it. The girl later sent the video to two friends by text message. When she later fell out with one of the friends, he showed the video to a school police officer. The prosecutor charged her with distributing child pornography, and Maryland's highest appellate court recently affirmed the conviction.
Questioning a Child: A Case Study
A military court of appeals recently made headlines when it dismissed child abuse charges against a Marine colonel. The very thorough opinion provides a good case study in the difficulties of interviewing young children. In both my experience as a civil lawyer defending youth organizations and my past life as a criminal prosecutor, I have seen inadequate interviews so taint a child's disclosure that it becomes impossible to know what actually happened.
Resilience After Child Abuse
One very important issue for youth-serving organizations is what factors help children recover from abuse or neglect. It is a complicated question, in part because children are at such varying developmental stages when they suffer maltreatment. A recent systematic review of several mental health studies offers possible factors that organizations can consider to help children overcome adverse experiences.
Questioning Children: A New Study
A recent study adds more support to the evidence that asking children open-ended questions is the best way to obtain the information that they have. Researchers studied 83 children in Australia, from ages 7-12. They showed the children a short film, and then interviewed them twice, once by a person who asked only open questions and once by a person who asked only closed questions. A third interviewer then asked the children their thoughts about the interviews using a 10-point rating scale.
Depositions of Children: How
The next, and for many lawyers the most frightening, issue in deposing children is how to ask questions of children. Like many tasks, it is more frightening than difficult. Fortunately, many other people have faced this same problem, and many of them have written some very instructive manuals.
Depositions of Children: Where, What, and Who
As I discussed in my last post, courts generally allow depositions of children who may have relevant information. That right is not boundless, however, and courts have the right to set conditions to reduce the stress and trauma to the child. Courts that have allowed depositions have either set the conditions themselves or required the parties to confer on various factors.
Continue reading Depositions of Children: Where, What, and Who ›
Depositions of Children: When and Why
One dilemma that lawyers confront is when and how to depose children. Sometimes, those children are the professed victims in litigation; other times they are fact witnesses. Quite often lawyers for the child's family will resist a deposition, citing the potential for psychological trauma. Most courts that have considered the question have found a right to a deposition, tempered by the need to make accommodations for the child's age, maturity, and potential for trauma.
Team Sports Increase Resilience
A recent study of more than 9000 young adults examined whether team sports helped children overcome adverse childhood experiences (ACEs). The researchers followed almost 10,000 teens for a decade, including almost 4900 teens exposed to ACEs and more than 4700 who were not. The study concluded that teens who participated in team sports had a 24 percent lower probability of receiving a depression diagnosis and 30 percent lower odds of receiving an anxiety diagnosis than those who did not participate.
- Construction
- Data Privacy
- Corporate and Business
- Employee Accomodation
- Mandated Reporter Laws
- Current Events
- Adverse Childhood Experiences
- Child Abuse Registry
- Depositions
- Staff Training
- Child Protection Policies
- Protection Policies
- Internal Investigations
- Speaking Engagement
- Risk Avoidance
- Charities
- Child Abuse
- Schools
- Criminal Law
- Mental Health Research
- Public Policy
- Resilience
- Employment Issues
- Bullying
- Over-Protection
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- Miscellaneous
- Negligence
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- Illness
- Mandated Reporter
- Media
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- Presentations
- Youth Camps
- Teresa E. Adams
- Deborah A. Ausburn
- James Balli
- Scott G. Blews
- Alisa P. Cleek
- Jonathan D. Crumly Sr.
- Glianny Fagundo
- Julian A. Fortuna
- Randy C. Gepp
- Shawntel R. Hebert
- Katie Heron
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- Donald S. Kohla
- Lauren Parsons Langham
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- Lauren Marlow
- Jan G. Marsh
- LaTise Miller
- Christina L. Moore
- Allen W. Nelson
- Michele L. Stumpe


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One of the biggest factors necessary to assure effective change is how well do employees respond to the change. Because let's face it. Employees are the one who will actually carry out the change.
Here are the seven key elements of an effective action plan that will facilitate employee acceptance of any change, big or small.
1) What are the goals of the change? What is the change meant to accomplish? Too often, employees are asked to adopt to change. Be that a change in procedure, technology, staffing or relocation, reorganization even downsizing without being told why such a change is mandated.
Now, old school management was to say, "Hey they don't need to be told why, just do it." But today's workforce they just won't accept, just do it at least not for long. Give employees the big picture.
Our expert mentioned in one of the workplace success audio conferences that employees who understand the overall purpose of the change are far more likely to cooperate with its implementation. Give clear and convincing reasons for the change.Push the change with all the enthusiasm you can master. Because change is frightening and anxiety producing for both people, they need your confidence in the benefits of the change. Tell the benefits loud and clear. Support your reasons for the change with solid evidence. Much like lawyer would build the rationale for his or her takes.
Be detailed. "Because it's good for the company" isn't a sound reason. "Because the studies we've done show that with this change we can shorten the turnaround time from order to delivery at the same time, as we decrease the number of steps you need to take." That's a sound reason.
Make it a winning proposition for everyone, the company and to the employees. If in the end, you deliver on your promises, the change does end up benefiting employees in the way you described. Every change you instigate thereafter will be accepted more and more willingly.
2) How will the change be implemented? Even when workers know a change is about to occur and why, they can be anxious about how the change will be implemented. Will outside firms be responsible for implementing the change? Will the change be managed entirely from within?
Healthcare Training Tip: Keep employees informed on a regular basis. Don't be hesitant about providing information even if you need to come back later and say, "Well, we expected to start with part A of the change but we found it makes more sense to start with part B. Here is why and how."
Use a number of methods to communicate how things will happen. Email, newsletters, bulletin boards, lunch time get together, and a good open door policy. All these will help employees look at the change in a favorable light.
3) Who is involved in the change? How does the change impact specific persons or departments? One of the mistakes companies make in their efforts to bring about change is failing to ask the employees involved how they would like to see the change take place. What concerns those employees have about how the change will impact their work current and future.
Inform employees fully about who will be involved in the change and what is expected of each of them. A well-informed employee can engage in the process successfully and uninformed one cannot.
4) What are the resources available for the change? Make sure there are sufficient materials, training, mentors, seminars whatever else is needed to facilitate the change. Not only that, but make sure the employees involved know well ahead of time what resources they will have access to. The more employees feel secure about what the future holds for them, the less likely they are to sabotage the change or resist it.
Healthcare Event Tip: Conduct informal focus groups. Say free brown bag lunch meeting to get discussion going with employees as to what resources they believe would be helpful. And don't just give their ideas lip service. Employees are often best place to know what is needed to do the job since after all, they are the ones on the job.
Engage employees in the process and the change will be much smoother. Use your most engaged employees to help. In other words, there will always be some employees who embrace the change wholeheartedly from the get-go.
These employees are precious resources for the company in assuring the change process. Ask for these employees' help in communicating with and motivating those who are less engaged. What resources to these committed employees' feel would be most helpful? Getting already engaged employees involve fosters, a sense of ownership which they can then transmit to other employees.
5) What's the timeframe? Is the change eminent? Is it a year down the road? What's the timetable and how does that affect those involved? A change that is slow in coming will have an entirely different motivation process than one which is happening next week. The time frame must be taken into account as you plan. How the change will be implemented and how will it affect different departments.
For any substantial change have time lines drawn out that are readily accessible on your company bulletin boards, on computers, such like giving dates when the different phases of the change will kick in. Include who's involved in each stage and who's the "go-to" person for that particular phase of the change. The more information you give employees, the less their anxiety, the more willing they are to cooperate and the easier the change.
6) Who is the "go-to" person? Or more accurately, who is the "go-to" person for each aspect of the change? Confusion and chaos are the enemies of successful change. In the absence of a well-defined "go-to" person, employees are easily confused and disoriented. They'll ask, "Well, where do I go for this? Who could answer that?"
You don't want your employees in such as a state. Help them out, designate "go-to" persons for each facet of the change and post the names of those individuals where employees can easily find them. Use as many of your already committed to the change employees as those "go-to" individuals as you can.
Have the "go-to" persons report to a designated manager in-charged of the change with any problems or issues they encountered along the way because that is a final element of an effective action plan for change.
7) What are the problems? No matter how carefully you planned for a change, problems arise from bumps in the road to full blown crises. How will you deal with those inevitable problems?
Oh, certainly having "go-to" employees who come to you regularly with the problems. They are made aware of is very useful. Be sure those "go-to" employees have their own "go-to" manager they can turn to when a problem arises.
You can find out about potential problems other ways too by conducting informal focus groups or meetings with the affected departments before and during the change process. Pay attention to company blogs and other sections, sources of information. Problems will often be revealed more readily there.
Strengthen you management skills and healthcare; know-how with healthcare compliance company management conferences at AudioEducator


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New York Knicks vs Brooklyn Nets
Hello world,
So much has happened in the sports world that I was waiting for things to settle down and the dust settled. I think it has for the time been. The London 2012 Olympics will now grab our attentions for the next two weeks. So let's start with the New York Knicks and Jeremy Lin. Why did Jeremy Lin leave NY Knicks? Who is sorry now? Did Houston or New York get win? This is very easy to call. Houston is a loser because they had Jeremy Lin and they did not pay him what he was worth, instead they let him go. Then he went somewhere else in order for Houston to see what they gave up, but now they have to pay Jeremy double for his trouble. That is what happens when people don't treat you right. Don't worry if they fire you or let you go because if you will keep trying someone else will see your greatness and the same people who let you go will have to pay you double.
Linsane No More
Now that Jeremy Lin is no longer a New York Knick- it is fair to say that Linsanity is over.
No matter how great he becomes it will never be the same as if he were in New York. Jeremy Lin seemed to have outsmarted himself. Jeremy Lin was taking the attention from the real superstars on the Knicks and he was also shooting the ball too much. In New York he was at the bottom of the totem pole but in Houston he can be at the top. If he doesn't make the best of his opportunity- Jeremy and the Houston Rockets will be the biggest losers.
Rockets Still Grounded
Had Houston not let Jeremy go, Linsanity would never have been born. Now that Houston Rockets have Jeremy Lin- are they still poised for takeoff. I don't think so at all. Jeremy has not had a chance to improve that much to help the Rockets make the playoffs. So, the only purpose for Jeremy Lin being back in Houston was for him to get his money. It is not about the New York Knicks, but about Jeremy Lin and the fact that he needed to make his money. We should wish him well in Houston for he is vey young, but if he already blew out his knee- the question is does he have longevity? Please feel to respond.


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Following its May meeting the Bank of England's Monetary Policy Committee (MPC) has announced that Bank Rate will remain unchanged at 0.5%. The decision reflects clearly how sentiment about the UK economy is changing. Go back a few weeks and my forecast that Bank Rate would be unchanged was at odds with the consensus (Is there any reason for the Bank of England to raise Bank Rate in May?). But by the time the MPC convened it had become clear that the time was not right for a further tightening of monetary policy.
The news is a further blow to savers who will continue to endure interest rates on their accounts that are below the rate of price inflation. With such negative interest rates savers should really be seeking alternative investments for money that can remain invested, and not drawn on, for two or three years at least.
Frankly there seems little prospect that interest rates will rise much, if at all, in the rest of this year as too many economic indicators are crying out for monetary policy to remain relaxed.
That adds up to eight good reasons for Bank Rate not to be raised. The direction of at least four of these economic factors needs to be reversed, in my view, before a rise in Bank Rate is necessary. How long will we have to wait for that to happen?
Martin Upton
Director, True Potential Centre for the Public Understanding of Finance (True Potential PUFin)
10th May 2018
True Potential PUFin is based at the Open University Business School in Milton Keynes, UK
True Potential PUFin is the first and only personal finance research centre in the UK that has an active teaching programme freely available to the public. Supported by the University's excellence in delivering distance learning, the Centre is uniquely positioned to develop the public's financial capability and to research the impact and effectiveness of its education programme.
True Potential PUFin is supported by a five-year programme of financial support provided by True Potential LLP.
The views of True Potential PUFin academics do not necessarily reflect the views of True Potential LLP
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On Hashish
Author(s): Walter Benjamin
Provides an intimate portrait of Walter Benjamin, venturesome at the end of the Weimar Republic, and of his unique form of thought. This English-language edition features a section of supplementary materials - drawn from Benjamin's essays, letters and sketches - relating to hashish use, as well as a reminiscence by his friend Jean Selz.
Product Information
Fascinating...On Hashish gives the reader a sense of Benjamin's philosophical method and a tour through the library (and the staggering erudition) that supported it, but also provides some insight into the man himself--his drives, his fears, and his creative process. -- Michael Berk Nextbook 20060516 In search of heightened awareness, Benjamin would eat hashish, smoke opium and get injected with mescaline...Some of his notes (such as the part about giggling) will be familiar to any contemporary stoner, but even when dealing with drugs he surprises his readers...Everything Benjamin wrote, even when the subject is less than pleasant, exudes an almost euphoric spirit. It was as if he wrote as a form of worship, out of gratitude for the chance to live and discover. -- Robert Fulford National Post 20060530 During the late 1920s and early 1930s, the radical thinker and cultural critic Walter Benjamin made a series of experiments with hashish, mescaline and opium...This very welcome collection is the first in English to round up his better-known drug pieces, such as his elliptical account of a hashish-intoxicated evening stroll around the port of Marseilles, and to place them in the context of the related notes, drafts and marginalia that track the course of his elusive and constantly evolving project. This is a very worthwhile venture, and one that produces a book much greater than the sum of its parts. Benjamin's scattershot approach to recording his drug experiences means that there are as many nuggets of brilliance (and as many incomprehensible rambles) in his notes and journal entries as in his finished prose. -- Mike Jay Fortean Times 20060901 [On Hashish is] a miscellany, gathering the protocols of [Benjamin's] drug experiments, two accounts of his experiences, and a handful of references to drugs culled from his other works. It can only begin to suggest the true importance of drug experiences for the development of Benjamin's thought. Yet for this very reason On Hashish stands in the same relation to a more conventional essay on drugs as Benjamin's literary essays do to conventional criticism...What makes On Hashish an important book is that Benjamin's drug experiments not only were a failure in themselves but also shifted the ground beneath his other work in a way that he never fully acknowledged. -- Adam Kirsch New Yorker 20060821 [Benjamin's] drug experiences show once again how singularly committed he was to the program of the avant-garde: overcoming the limitations of the self by subjecting it to an array of pulverizing, Dionysian, ego-transcending influences. -- Richard Wolin The Nation 20061016 Drugs did, mostly, make Benjamin smile, and what could bring smiles to the lips of this proud, gifted and doomed man can't but bring smiles to the reader. There is wonderful writing in this book, much of which illuminates Benjamin's better known, equally suggestive, and no less enigmatic texts. Plus, here, we catch him tapping his foot. And smiling. -- Harvey Blume Jerusalem Report 20061016 Harvard's pocket-sized On Hashish, edited by Howard Eiland, brings together everything that Benjamin ever wrote on the subject. It includes notes by him and his friends about the drug protocols and two essays. One of Benjamin's solitary experiments ended up as the basis for 'Hashish in Marseilles,' an essay that begins with him sitting in his hotel waiting for the drug to hit and then follows him around the streets. At points along the way, he giggles at his own jokes, has paranoid thoughts, feels the immensity of his solitude, and gets hungry. A piece of ice brings enormous pleasure; Pate de Lyon reminds him of the words 'Lion paste'; the name of a boat in the harbor makes him think of aerial warfare; and he passes two men on the street who remind him of Dante and Petrarch. -- Eric Bulson Times Literary Supplement 20070420 Benjamin's work continues to fascinate and delight because it has something for everyone: the literary critic, art historian, philosopher, urban theorist and architect. Whether he is talking about children's toys, Mickey Mouse, Surrealism, photography, or Kafka, Benjamin has a knack for figuring out what they can tell us about the wider world that produced them. -- Eric Bulson Times Literary Supplement 20070420
Walter Benjamin (1892-1940) was the author of many works of literary and cultural analysis. Howard Eiland teaches literature at the Massachusetts Institute of Technology. Marcus Boon is Associate Professor of English, York University, Toronto.
General Fields
- : 9780674022218
- : Harvard University Press
- : The Belknap Press
- : June 2006
- : 190mm X 140mm X 14mm
- : United States
- : books
Special Fields
- : Walter Benjamin
- : Paperback
- : en
- : 834.912
- : 208
- : 4 line illustrations


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Showing 25 of 35 results
We present direct measurements of the $Z~0$-lepton coupling asymmetry parameters, $A_e$, $A_\mu$, and $A_\tau$, based on a data sample of 12,063 leptonic $Z~0$ decays collected by the SLD detector. The $Z$ bosons are produced in collisions of beams of polarized $e~-$ with unpolarized $e~+$ at the SLAC Linear Collider. The couplings are extracted from the measurement of the left-right and forward-backward asymmetries for each lepton species. The results are: $A_e=0.152 \pm 0.012 {(stat)} \pm 0.001 {(syst)}$, $A_\mu=0.102 \pm 0.034 \pm 0.002$, and $A_\tau=0.195 \pm 0.034 \pm 0.003$.
The polarization of tau leptons in the reaction e+ e- --> tau+ tau- has been measured using a e+e- collider, TRISTAN, at the center-of-mass energy of 58 GeV. From the kinematical distributions of daughter particles in tau --> e nu nu-bar, mu nu nu-bar, rho nu or pi(K) nu decays, the average polarization of tau- and its forward-backward asymmetry have been evaluated to be 0.012 +- 0.058 and 0.029 +- 0.057, respectively.
Cross-section and angular distributions for hadronic and lepton-pair final states in e+e- collisions at centre-of-mass energies between 189 GeV and 209 GeV, measured with the OPAL detector at LEP, are presented and compared with the predictions of the Standard Model. The measurements are used to determine the electromagnetic coupling constant alphaem at LEP2 energies. In addition, the results are used together with OPAL measurements at 91-183 GeV within the S-matrix formalism to determine the gamma-Z interference term and to make an almost model-independent measurement of the Z mass. Limits on extensions to the Standard Model described by effective four-fermion contact interactions or the addition of a heavy Z boson are also presented.
This final analysis of hadronic and leptonic cross-sections and of leptonic forward-backward asymmetries in e+e- collisions with the OPAL detector makes use of the full LEP1 data sample comprising 161 pb^-1 of integrated luminosity and 4.5 x 10^6 selected Z decays. An interpretation of the data in terms of contributions from pure Z exchange and from Z-gamma interference allows the parameters of the Z resonance to be determined in a model-independent way. Our results are in good agreement with lepton universality and consistent with the vector and axial-vector couplings predicted in the Standard Model. A fit to the complete dataset yields the fundamental Z resonance parameters: mZ = 91.1852 +- 0.0030 GeV, GZ = 2.4948 +- 0.0041 GeV, s0h = 41.501 +- 0.055 nb, Rl = 20.823 +- 0.044, and Afb0l = 0.0145 +- 0.0017. Transforming these parameters gives a measurement of the ratio between the decay width into invisible particles and the width to a single species of charged lepton, Ginv/Gl = 5.942 +- 0.027. Attributing the entire invisible width to neutrino decays and assuming the Standard Model couplings for neutrinos, this translates into a measurement of the effective number of light neutrino species, N_nu = 2.984 +- 0.013. Interpreting the data within the context of the Standard Model allows the mass of the top quark, mt = 162 +29-16 GeV, to be determined through its influence on radiative corrections. Alternatively, utilising the direct external measurement of mt as an additional constraint leads to a measurement of the strong coupling constant and the mass of the Higgs boson: alfa_s(mZ) = 0.127 +- 0.005 and mH = 390 +750-280 GeV.
Hadron production and lepton-pair production in e+e- collisions are studied with data collected with the L3 detector at LEP at centre-of-mass energies sqrt{s}=192-208GeV. Using a total integrated luminosity of 453/pb, 36057 hadronic events and 12863 lepton-pair events are selected. The cross sections for hadron production and lepton-pair production are measured for the full sample and for events where no high-energy initial-state-radiation photon is emitted prior to the collisions. Lepton-pair events are further investigated and forward-backward asymmetries are measured. Finally, the differential cross sections for electron-positron pair-production is determined as a function of the scattering angle. An overall good agreement is found with Standard Model predictions.
We report on measurements of e+e- annihilation into hadrons and lepton pairs. The data have been collected with the L3 detector at LEP at centre-of-mass energies between 130 and 189 GeV. Using a total integrated luminosity of 243.7 pb^-1, 25864 hadronic and 8573 lepton-pair events are selected for the measurement of cross sections and leptonic forward-backward asymmetries. The results are in good agreement with Standard Model predictions.


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Australians are spending $45 billion each year on eating out, according to a report put together by Future Food. However, they're aren't interested in greasy foods, they're craving healthy options. That means the products you're serving as a restaurant or caterer need to be fresher than ever.
It's essential that you keep your stock at the perfect temperature otherwise you risk spoiling the food and losing money. In order to keep track of it all, you need the right instruments for every step of the journey.
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There's a lot of room for error during the transportation of incoming goods as the cargo can go a while without being checked on, plenty of time for goods to go off if the temperature isn't right.
The Testo 104-IR allows you to carry out inspections of incoming goods and spot check during transport or food inspections. This pocket-sized thermometer measures both incoming goods and surface temperature of the individual foods or whole pallets. It features a folding probe to measure core temperatures of products. When the probe is away, the infrared measurement can be turned on for surface measurements.
Looking after goods in storage
Once the food has made it to storage, it's important that temperature monitoring continue to be a main priority. This can involve reading loggers for different measurement locations which can be troubling if you aren't able to catch an error in time to avoid spoiling goods.
Our Wi-Fi data logger system testo Saveris 2 gives you eyes over temperature and humidity automatically, sending the measurements to the cloud. You can access this information any time from your smart device allowing you to fix inaccurate temperatures before they become a bigger issue.
To learn more about how Testo's instruments can transform your restaurant or catering system, contact our team today.
Measuring temperature during preparation
When you're getting ready to prepare your food, it's important to do a double check of the food before you start cooking it. Of course, this can get tedious if you don't have the right tools to provide you with quick measurements.
For quick, reliable measurement readings, turn to the Testo 106 food thermometer. It measures up to two measurements per second, getting right to the core temperature of the food. And don't worry about your presentation, the measuring tip was designed to ensure you can hardly see the puncture mark.
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Before the food is served, it pays to do a temperature check to ensure the food isn't going out undercooked. Again, this is an area that could slow you up if you don't have the right tools.
The Testo 104 food probe thermometer is essential to quality assurance, cold chain documentation and hygiene regulations. It allows you to do a quick spot check, probing the core temperature of liquid, semi-solid and viscous media. Again, its probe is slim so your patrons won't see the puncture mark when you serve them. It's HACCP compliant and waterproof, perfect for your kitchen.
To learn more about how Testo's instruments can transform your restaurant or catering system, contact our team today.


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Welcome to episode 30 of the Ready for More! Podcast. I'm so excited to have made 30 shows. It has been such a great experience and journey bring value to you through the Monday morning tip and Thursday interview shows. I've loved sharing the stores and expertise of 14 amazing women from all over the world.
To celebrate my 30th episode, I put together highlights from all of the amazing women. For each guest and episode I've share one value add snip-it of our conversation and each woman's parting advice for women business owners who are Ready for More!
- 2:28 Sophie Bennett Episode 2 – Find Your Flame
- Develop an Olympic attitude – be fully responsible for your future
- Sophie's advice for women who are Ready for More: "Decide what you want and commit to it."
- 5:12 Robin Meyers Episode 4 – Unleash Your Potential
- The four triggers of self-doubt – 4 "H's"
- Robin's advice for women who are Ready for More: "You have the power to do anything you want at any age. Don't let what you think is impossible, stop you. Your impossible is totally possible. You have to total control over that, no one can take that away from you."
- 7:35 Julia Jones Episode 6 – Rewrite Your Stories
- Use your "Thought Ladder"
- Julia's advice for women who are Ready for More: "I think that finding a way to tell yourself and believe that you can do this, is some of the most worthwhile work that you will do in building your business."
- 11:57 Elena Sonnino Episode 8 – Living Fully in the NOW
- Planting Seeds and cultivate what you plant and let it grow
- Elena's advice for women who are Ready for More: "You have everything you need already inside, that inner strength and wisdom. Tuning into that might just be magic and the sunrise that you need."
- 16:40 Tsufit Episode 10 – Step into the Spotlight
- Focus on the one "door" to your business, so potential clients are clear where to enter
- Tsufit's advice for women who are Ready for More: "You have to know when to sit down and shut up. Saying more doesn't always sell them more."
- 22:14 Marina Pearson Episode 12 – Leading a Joy Lead Life
- How can your business support you to lead the lifestyle you want?
- Marina's advice for women who are Ready for More: "Have fun and don't take life too seriously."
- 27:11 Karen Trepte Episode 14 – Pay Yourself First
- Let yourself learn, make mistakes and love yourself
- Karen's advice for women who are Ready for More: "Pay yourself first!"
- 30:18 Michelle Durand Episode 16 – Tears to Treasures
- Creating a business around a sensitive topic – Abortion
- Michelle's advice for women who are Ready for More: "Go for it! Whatever it is, if you are feeling lead in your heart, in your passion, and your gut is telling you to do something and you're scared as heck. Got for it!"
- 34:48 Caroline Wood Episode 18 – The Power of Systems and Numbers
- Systems and simplifying your business
- Caroline's advice for women who are Ready for More: "You shouldn't be afraid of your numbers. You need to come grips with them if you are going to be serious about your business. You have to understand the numbers. Yes, you can outsource a lot of that work but the key numbers, you as a business owner, really need to understand to step up to your role as being a CEO."
- 42:03 Kim Knight Episode 20 – Manage Stress, Health & Well-being
- Most important lessons: 1) Believe in what you offer and have a desire to be help and service 2) Have the right support system 3) Find emotional support
- Kim's advice for women who are Ready for More: : "Be true to oneself and look after oneself. To really understand oneself. That means more than your physical body and our personality; it is about getting to our true self and being guided by that"
- 45:30 Jayne Hopper Episode 22 – Your Personal Brand
- Find your personal brand and how to look good on video.
- Jayne's advice for women who are Ready for More: "Be yourself and find the right people to support you on this journey."
- 50:32 Yasmine Khater Episode 24 – The Art of Sales
- The four triggers of self-doubt – 4 "H's"
- Yasmine's advice for women who are Ready for More: "You are amazing. You can make things happen that's will really change and transform the world."
- 53:42 Nicole Burgess Episode 26 – Embrace Your Strengths
- Put systems in place to make things easier
- Every step we take is part of our learning path
- Nicole's advice for women who are Ready for More: "To be you. To do what really does light you up. And keep taking those small steps to follow that dream and that passion that you have."
- 57:32 Lisa Murray Episode 28 – Making a Business Out of Being Creative
- Planting Seeds and cultivate what you plant and let it grow
- Lisa's advice for women who are Ready for More: "Find the joy. That comes from trusting yourself and know that every single choice you make, makes a difference somehow. And when you actually put those two things together and start to trust your choices, the joy has to come."
Connect with Heather:
Join our Facebook Community: Ready For More! Women Business Owners Circle
Facebook: www.facebook.com/igniteyourmarket/
Instagram: www.instagram.com/heathercameroncoach/
LinkedIn: www.linkedin.com/in/cameronheather/
Download Your Should Buster: www.igniteyourmarket.com/shouldbuster
- Are You Unknowingly Losing Leads on Facebook? - April 22, 2020
- 3 Business Lessons from Leonardo Da Vinci - March 10, 2020
- Ignite Your Market Challenge: Finish - February 24, 2020


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Okay, so, I'm trying to give a good friend a really great x-mas gift, and I need some help.
On her wishlist was .Hack//Infection for the PS2. Well, I happen to have that, Mutation, and Outbreak just sitting in a box with no intention of being played again. I feel really bad gifting her three of the four parts and started hunting for the last part, Quarantine. The cheapest used copy on Amazon is $80, and my local old used game store hasn't seen a copy of it in quite some time. So I have come to TAY. If anyone has a copy, or can locate a copy of .Hack//Quarantine, I would not be opposed to paying at least $35 (the price Play 'n Trade would have sold a copy to me) for it. So, can anyone help me pull of a Christmas Miracle?


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MORRIS – Law enforcement officials are investigating an apparent drowning after a body was found Thursday afternoon in a private pond located at U.S. 6 and Seneca Road, according to a press release by the Grundy County Coroner's Office.
"The subject was discovered by a couple fisherman," the press release stated. The press release stated the coroner was called to the scene at 4:10 p.m.
The subject was taken from the water with the assistance of Morris Fire Department Water Rescue Team at around 6 p.m..
The coroner's office, Grundy County Sheriff's Office and Illinois State Police Crime Scene Services are investigating.
"Coroner (John) Callahan states this death could be related to a traffic crash that had occurred several months ago at the Seneca exit," the press release read. "The driver of that crash had never been found."
The identity of the deceased is being withheld pending notification of next of kin and an autopsy is scheduled for Friday.


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Covid-19 Info: We appreciate your support of us and other small businesses and are committed to keeping our staff and customers healthy and safe during this difficult time. Please expect delays in shipping and restocking. See updates on issues caused by the Covid-19 Pandemic here and our company Facebook Page.
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The question often arises, "Jimmy, what do you really think is going to happen with this whole asking famous people for money thing?"
Easy. Famous people will give me money. Next question.
Okay, so maybe that's not going to happen, still it's not totally out of the realm of possibility, right? After all, we live in a "realm of possibility" where there are people who actually give money to Spencer Pratt to, uh, speak and breathe (often at the same time, which is no small feat for him). I mean come on people, Spencer Pratt. It's right there in his name. I've got to have more value than that guy.
Okay, so let's say no one cuts me a check, what else is there? Well, there is exposure. There is publicity. There is the hope that more people will read my scripts and tell me how great my writing is (but then not give the standard "it's not what we're looking for at this time" part of the speech that I've heard far too often.)
Sure, there are proven ways to go from being an unproduced screenwriter to standing at the Oscar podium accepting an award for your first script that are more acceptable. I could start stripping tomorrow and put my musings in a blog and just start writing my acceptance speech, but I figure I'll give this a shot first.
Maybe I should start waxing though, just in case…


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Today was another good day with a repeat of an unexpected complication. This morning after getting up, I suddenly got very dizzy and my stomach got queasy. A repeat of what happened 2 days ago, but today there was no Fentanyl patch change day. So the possible link may not be the reason for both complications. I took immediately Zofran and Meclizine which got it under control. After having just a slice of toast I was ready for my morning walk with Dianne.
We started our walk after Dieter and company left to go home to Valencia a neighborhood in Santa Clarita located within the northwestern corner of the Santa Clarita Valley in Los Angeles County, California. Dianne picked today's photo theme, car tail lights. These PICTURES are good examples of primary shapes include circles, squares, triangles, and hexagons.
Getting back from our walk we needed to rush a bit to get to the Streets of Brentwood mall to see the movie Mission Impossible – Fallout. With previews, the movie was three (3) hours long. It was an action packed movie, at the least the last 2/3 of it since I fell asleep for the first 1/3 of it.
After the movie, we went back home doing a bit of house cleaning now that our guests are gone before resting and watching a romance movie before dinner. For dinner we had leftover Skipolini's pizza, not much to add that was said yesterday about it. The dessert was a leftover chocolate peanut butter cake. After dinner, we watch some more TV before calling it a day.
Picture of the Day
2018-08-12 – Photographic principle – Shapes (Part 2)