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Blog Archives
Marxist Ignorance
This morning I read an article on this website called Socialist Appeal about science and how those of any religion tend to be ignorant of science. It also speculates that once material wealth is abundant for all that religion would disappear entirely.
The coming socialist revolution will establish universal high-quality education, placing the wondrous power of modern technology at the feet of the people and allowing it to be used according a democratic plan in the interests of all. This revolution will be the negation of all traditional faiths and superstitious rituals, as people voluntarily drift away from these, on the basis of material wealth and security, available for the first time to everyone.
That's a bold statement to make considering that in most cases becoming religious or spiritual isn't because a lack of security and/or material wealth, but rather the emptiness produced by being solely reliant on such. This is one classic example of the ignorance shown by Marxists in general, they believe that once people are "happy", within a materialistic and superficial paradigm, that religion will disappear. Well, Christians believed this very same thing when they converted our ancestors from paganism to Christianity, that once the light of Christ entered the souls of the pagan that "happiness" would become more common place in society. However, with the resurgence of paganism, especially in Iceland a country that should be, by all means in the realm of socialism, "happy", but somethings missing apparently that Iceland is the first nation in over a thousand years to build a pagan temple to the old Norse Gods. Scandinavian socialism is held in such high regard by socialists in the West, so shouldn't the Marxist hypothesis be true in this respect? Seems like the hypothesis is null and void because for a nation to be abundant and accepting enough to allow a pagan temple to be built shows that religion will never die out no matter how much the Marxists want their ideology to be held in sacrosanct.
I'm coming from this as someone highly into the sciences and currently attending college for a Biotechnology degree, so to assume because I believe in multiple Gods doesn't mean I'm an ignorant simpleton. In fact, the director of the National Health Institute and leader of the Human Genome Project, Francis Collins, is a Christian, though not a Creationist Christian, but a Christian who believes in Yahweh and Jesus Christ. I seriously doubt this man would've been allowed to conduct such an important project if he were simply a feeble minded, Dark Age mystic. Another example is my father, another Evolutionist Christian, who most likely has a genius IQ with all the things he DIYed and the problem solving skills shown. However, Marxists would figure him to be a superstitious dolt.
Within much of the Leftist spectrum is a tendency to be shameful of the actions of their ancestors, which is called "white guilt". I find this trend to be ridiculous and a sign of a weak mind. Since Lizzy Borden is my distant relative, should I feel shameful for her acts of violence? Gods no! Why would I since I wasn't even born then? So it must be asked why white Leftists should shame and induce shameful feelings within other white people about actions they themselves had no hand nor control over? No one should have any shame for what their ancestors did, because there is nothing you can do to change the past. The past is an immovable mountain, however the present and future is quite malleable. You affect change now instead of wasting your time feeling guilty for the past that you had no hand in. One of those discussions we need is the discussion that eliminates the idea of melanin based racial labels and viewing all people as what they really are: The Human Race. However, Marxists still enjoy dividing people up into small, easily controlled parcels of human beings in order to better control their attempt at social engineering. It's the same tactic used by the two major parties in power in America today, the Democrats and Republicans. In order to keep absolute power the people must be absolutely divided.
I used to be a Marxist years ago and I have no regrets. After all, it helped me formulate my slight socialist with a libertarian edge ideology. I consider myself patriotic in regards to my country and I support the Constitution. It's perhaps one of the most perfect documents outlining our freedoms these days. I support the 2nd Amendment to the point where I believe open carry should be allowed. Though I would prefer a battle axe to a gun, but to each their own. I support states rights and a decentralized form of government, meaning that the Federal Government interferes as little as possible with what states and their population vote and decide for themselves. I support gay marriage and gay adoption. I don't see anything repulsive about this. I support Universal Healthcare, which I think can still be decided by states to implement or not without the Federal government. I'm neutral on abortion. I have my reasons, but I'll keep them to myself. I believe in absolute religious freedom which extends to businesses as well. If a business wishes to not patronize a certain group of people, that's their right. However, they must not whine about the loss of profits due to their decision. This of course goes beyond Christian businesses, but also other religiously based businesses such as pagan ones who wouldn't want to patronize Christians or other monotheists. I'm pro-animal rights and pro-environment, obviously.
That's just a few things where no one can truly pinpoint my ideology, which I think if anyone follows one ideology to the T, then it's nothing more than ignorance. I believe both sides of the political spectrum have something to contribute to our political system. Whether socialism or capitalism wins out for absolute control of a country it's simply totalitarianism.
Posted in Uncategorized
Tags: america, american, americans, appeal, atheism, atheist, belief, black, blacks, capitalism, capitalist, center, christian, christianity, communism, communist, conservative, creationism, democrat, democratic, evolution, faith, gay, guilt, ideology, ignorance, international, intolerance, league, left, leftism, leftist, lgbt, liberal, marriage, marxism, marxist, pagan, paganism, progressive, race, racism, religion, religious, republican, rights, science, socialism, socialist, tolerance, white, whites, wil, workers
Why Race Needs to Be Obliterated From Human Minds
As we progress further into the 21st Century, racial tensions have increased by the simplistic manipulation by the New Royalty aka the politicians of both the Left and the Right and the Race Baiting minions of said politicians. Race is the disease that infests the human mind like a virus running rampant destroying life giving cells on the body. Instead of destroying the body of the host, it destroys the mind of the person and creates the illusion that we humans are different in any way. Except we aren't different, we are all of the same species. The only thing different is the amount of melanin contained within the flesh of human beings. This is simply superficial, but because we are a superficial species race tends to be held sacrosanct, an idol of worship that a lot of people get on their knees and blindly follow. Race, in other words, is nothing but an illusion created by the powers that be to control the population via forced culture (aka stereotypes) and absolute division. With unity of the human species comes true solutions and power unlike anything we have ever seen.
If humanity were to cast aside their pride and realize the destructive nature of recognizing race, we would be able to solve the problems that afflict this planet because no borders would separate us anymore. We would be united for the common cause of bettering our species. We could finally prove to the universe that we are a species able to overcome our petty, superficial differences. People like David Duke, Saida Grundy, and other race baiting, fear mongering zealots would not be able to profit anymore on keeping humanity divided. We would be too educated afterwards to allow these hateful zealots room in our hearts and minds. We would finally be set free from the shackles that recognizing race puts us in. Our full potential would be used once and for all for everyone and not a select few.
Humanity must once and for all be united as one race, the Human Race! That is who we are regardless of the traits of high melanin content or not given to us by evolution of our species in certain environments. We are Human Beings, not black, white, red, brown, yellow or whatever else. Those superficial labels destroy our species, keeps us divided, and harms people along the way. Racial recognition is an evil that needs to be stamped out like an ember that threatens a forest on a dry, summer day. Today, from here on out, make a commitment to yourself and others that you will no longer see them as one of those superficial labels, but as a fellow traveler on our planet Earth, as a Human Being! Boldly proclaim that we are all Brothers and Sisters of Earth and of one race, the Human Race! This is the revolution we truly need right now!
$15 an Minimum Wage Hike?
So when in our sordid little world did flipping burgers become a career? Probably since when people stopped having ambitions I. Life to be better than they are now which coincides to the lack of innovation in this country and a piss poor public education system that churns out drones rather than innovators. Why is it that minimum wage earners feel they are more entitled to more pay while the rest of us have to live on less than what they are asking fondue to pay freezes? I went to college for my profession, graphic design at $10.75 an hour that includes a pay freeze AND furloughs, so why should a minimum wage worker make more than me? Minimum wage is around for a reason:
a). With workers being paid cheaply it also means cheaper goods for the consumer. Once you raise the wages of an employee, especially to $15 that means higher priced goods which in turn means less customers and then that means layoffs of employees
b). It's a way to spurn an individual to achieve a better quality of life by thinking to themselves, " Wow this job sucks, I can do better!" And thus pushing them to do elevate themselves out of a crappy job.
But people these days have been raised, with the help of government propaganda, to believe they are entitled to the fruits unearned by them. What they have no understanding of is simple economics and what a $15 wage will mean in the long run. If they had an inkling of economics they wouldn't be asking for such a wage. Of course, you will have the race card bearers saying that anyone against this wage hike is racist. On the contrary it's actually racist to assume that a majority of minimum wage earners are mostly minority. Minimum wage jobs aren't just populated by minorities but by whites as well. So remember that when you speak against minimum wage hikes that you are dealing with veiled racists who will project their racism on you.
Such extreme wage hikes will spell doom for more workers rather than save them from the so-called capitalist doom that socialists try to fill their heads with. With today's technology it's possible to cut out human labor and replace it with automation. All you have to do is go look in your nearest grocery and see the self checkout aisle where automation has become a staple. This is the future of the overpaid, low skilled worker that the socialists want: automation.
The Evilness of Socialist Appeal
Much is to be said about socialist and the dangers it poses, as shown to us by history over and over again, but one can not ignore the absolute ignorance to history that many of these socialist groups hold. One of them comes to mind is Socialist Appeal, which is the publication organ of the Workers International League ( aTrotskyist based socialist organization), which many of it's members regard Trotsky as the saviour of communism in the same religious zeal Christians have for Jesus. Not only do they have this zeal and ignorance of history, but they also twist history of socialism to suit their means and call anything that goes against the grain of their current beliefs as revisionism and capitalist propaganda. If that doesn't make these folks seem heinous enough it is their undying support of Venezuela and it's failed socialist program, which as we speak is degrading into the same Stalinist dictatorship that Trotskyists despise. They ignore the obvious evilness that Chavez and Maduro indulge in to bring about THEIR vision of a socialist utopia in order to prop their highly held faith that socialism can't fail. As history has taught us that socialism does and will always fail because it lacks any common sense planning. It goes from point A to point C without any thought of how to properly go to point B first. The basic understanding of economics and how to create a sustainable system are lost to socialists because they would have to admit that a socialist economy can not and will never work. It is the basis of why China and many other surviving socialist nations have switched to market socialism it's the only way that they can survive. If they stuck with an orthodox socialist economy then those nations would've collapses ages ago.
There is a reason why no true socialist nation exists today because it doesn't work. It negates certain variables such as market forces, individual human beings and their wants, and how to maintain the dynamics of a successful economy. Though capitalism has a bad rep these days it is still the most thought system that improves with the times and generates surplus wealth for people thus providing a better standard of living for people. Socialism has yet to even produce a better standard of living for people and continually blaming it on capitalism is more than truth denial and a facade to escape the responsibility that socialists have in admitting their faults in their silly ideology.
Speaking of facades, the main facade that entices people to socialism is the idea of a 'workers government'. Sounds awesome, but the reality is that it will never happen because once the elitists of the socialist organizations have their grubby hands on power they'll rule IN THE NAME of the worker, but without letting the workers have any power whatsoever because workers aren't ideologically homogenous. No, in fact there are workers who have Leftist to Right Wing views with Libertarianism thrown in between the cracks. So to give workers power would also giving those who are your ideological opponents power as well, which is something socialists will never do. No matter their claim to tolerance they truly have no tolerance for outside thinking. They'll lambast and chastise you for your beliefs until you leave their cadre. That is the true face of socialism, an intolerant system that seeks sublimation of ALL people to the will of the so-called Workers State.
So whenever you encounter a socialist and get a whiff of bullshit you haven't stepped in doggie landmines, it's just the elitist, hipster spiel of the socialist thinking they are morally superior to you. Just remember the facts, they aren't morally superior and wouldn't even know the meaning of it because forcing people into a system isn't moral much akin to forcing socialists into a capitalist system (hence I'm all in favor of communes based of ideologies) and their ignorance is much to grieve about when it comes to socialists. Never hate them, just feel sorry for them. They need it.
The Blunder Games
Since October 1st, the staple of the Obama Administration and perhaps only victory has been less than successful. The rollout has been plagued with many technical difficulties that it should be simply replaced with a sign saying, "Sorry, we're experiencing technical difficulties. Please stay tuned!" However, despite the multitude of problems the Obama Administration is still saying ObamaCare is a good product. How can that be when the website isn't even entirely operational? You can't get a website that has been in the making since March of 2010 up and running, how do you expect to be the handler of peoples health insurance? I'm sorry, but the Obama Administration either planned this debacle in order to make way for a single-payer health care system or they are the biggest bunch of dolts the world has ever seen, from Obama down to Sebelius. What's even more ridiculous is the fact that Obama has stated that NO ONE will be fired over this extreme waste of taxpayers money! I mean nevermind the other stuff that has come out about this website and who made it, CGI a Canadian company that has a track record of messing up, but the enormous waste that this website poses is something that should outrage taxpayers. This is your money at work and the problem is that it is NOT working! It is so messed up that even the DEMOCRATS are agreeing that the forced individual mandate should be delayed. That's pretty big if the Democrats are even saying, "Hey since the website is messed up we should delay the individual mandate." Maybe they aren't so stupid after all.
Perhaps the worst aspect of this whole blunder is that people, who were told by Obama that they could keep their current plans, are losing their plans at a rate that outpaces people who sign up for ObamaCare. This is despicable and should be shunned by the Liberals because we all know how much they hated it when Bush lied, but so far the cries of foul have been minimum in comparison to the cacophonous cries of foul when Bush Lied. I guess when you have one of your own in power the standards at which a leader leads and what they state can be shrugged off. Point is Obama lied about his policy and now people who HAD health insurance are now losing it because of ObamaCare and this is unfair to those who had it. Should we blame the insurance companies? Partially, but the majority of the blame lies on Obamas shoulders. This is HIS pet project and is HIS achievement, so he needs to own up to this blunder. People are now suffering because of his plan.
Is this the Hope and Change that Liberals wanted? If so, you're pretty damn sick and twisted, but if not then you need to hold your President Obama accountable for his mistakes. You need to prove that you Liberals aren't the sick and twisted type who bow down to Obamas feet repeating in your mind, "The Messiah makes no mistakes!" while making excuses for his screw ups. Make him own his mistakes and then maybe we can take you seriously again. This Affordable Care Act is the biggest blunder since the Patriot Act and is about to surpass it in it's ridiculousness. If Obama doesn't own it and the Liberals don't eat the crow handed to them then both Obama and the Liberals lose ALL credibility or what credibility they had left. These Blunder Games need to end and soon because the cost on the American People for generations is far too great, both physically and financially.
Posted in Uncategorized
Tags: act, affordable, blunder, care, chaotic, communism, health, healthcare, nazi, obama, obamacare, pos, socialism


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You can get the HIGHEST QUALITY CDL TRAINING for THOUSANDS LESS... and Be CONFIDENT Knowing you are QUALIFIED to drive for the BEST Driving jobs and the best class a driver training.
Every profession has it's pros and cons. Trucking CDL is no different. The trouble is, the "cons" can cost you a LOT of time and money.
On the other hand, the "pros" can accelerate how far you go in your chosen profession of truck driving.
On that note, I just reviewed a copy of Allen Smith's Truth About Trucking program.
There's some great information on there.
Allen covers the following and more...
* Learn How You can Get a Better Education By PAYING LESS MONEY.
* A State by State Listing of The Best Truck Driving Schools
* The Big Leasing SCAM - How the Trucking Companies manage to make Thousands while the driver loses their shirt (and pants).
* Important steps to setting up profitability as an owner/operator from buying your rig to fuel taxes, and everything in between.
* Which smart-trucking-jobs that pay the most for professional truck drivers.
* The BEST and CHEAPEST route for CDL training!
* And Much, Much More...
His program used to be in just a plain old digital ebook. But there was such a strong interest to have it in audio format that he actually brought in an audio production company and got it released ... in fact, it's now a 2 CD set
Great decision as I don't know many who want to be sitting at their computers to read a digital book.
Now truckers, trucking students and anyone just looking into the industry can put the audio into their CD players and review all this.
And I certainly recommend doing so.
The downside is that through nearly 30 years of being heavily involved in the trucking, Allen Smith has obviously been impacted by the pitfalls of the profession ... so his audios do have a bit of a pessimist undertone.
But, as you'll discover, he's as genuinely interested in providing guidance and direction as he is experienced to talk about truck driving.
He's a very sincere and VERY experienced individual.
I recommend taking a peek at what he and his wife Donna have assembled.
At their page, you can also grab a free copy of 3 brief reports: * "Guide to Pros and Cons to Trucking" * "Truck Driving Careers: Choose the Right Truck Driving School or Trucking Company" * "Truck Driving Schools and Student Responsibility" Again, go check out their website for more information ...
Jun 18, 20 08:22 PM
Hello! I'm curious about what exactly the hub mileage is used for. I see hubodometers on trailers all the time on the road, but am curious are they still
Jun 15, 20 07:42 PM
Small mom and pop otr cheap pay companies or foreign owned companies don't give a darn about dac but yes it's highway robbery that report I can never work
Jun 09, 20 05:29 PM
a street sweeper that has the capacity of holding a 125 gallons of water. Does that require a tanker endorsement on my licence

subset: commoncrawl


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Eric Hosmer- 1B- SD- Idea- Hosmer had a very productive season against RH pitching last season, with a slash line of .335/.410/.528 against them. Her normally performs much better against RH than southpaws. Charlie Morton had a season of reverse splits in 2017, holding LH hitters to a .172 average. This was out of his norm, as his career slash line against LH hitters is .283/.375/.442. Morton enjoyed a .244 BABIP against LH hitters last year, which offers some explanation for his unusual numbers. Given the longer track records of the veterans, Hosmer is the better bet in this matchup. Value play- Draft Kings salary $3200
Ian Happ- OF- CHC- Cold- You might think that Happ's .179 average would be due to bad luck in a small sample size. Then you'd look at his .400 BABIP and wonder what was going on. The problem for Happ is that he hasn't put enough of the "balls in play" part to get a boost from his BABIP. After going 1-for-5 with 3 Ks yesterday, Happ has struck out 17 times in 30 PAs in 2018. Joe Maddon can't keep Happ in the lineup, much less at the top of the order, with that kind of performance (unless Maddon is staying cool by using Happ's bat as a fan.) Happ struck out a lot last season, also, but it took him 13 games and 52 PAs to get to 17 Ks in 2017. I see a trip to Iowa in Happ's near future if he doesn't turn things around quickly.
Maikel Franco- 3B- PHI- Hot- Franco got the most RBIs of any Phillie in their 201- shellacking of the Marlins. He knocked in 6 and scored 2 in his 2 for 5 day. Both of Franco's hits were for extra bases; a double and homer. He now has a .316 average early in the season, going 6-for-19. Four of his 6 hits are for extra bases. Franco hasn't been the beneficiary of extraordinary luck, with a BABIP of only .286. A very promising sign is that his Batting EYE is at 1.00 as he has walked and struck out 3 times so far. It's way early, but Franco is showing signs of the potential he has long had.
Chris Owings- SS- ARI- Stats- Is Owings going to be the first major leaguer since Ted Williams to hit .400 in a season? Not unless his BABIP of .600 keeps rolling along. Owings has also struck out 8 times in his last 5 games, giving him a 32.1% K% for the season. Both of those numbers should go down, which makes his projected .273 average still a reasonable mark.
Ender Inciarte- OF- ATL- FYI- Slow starts are nothing new to Inciarte. His career average is .261 in March and April for the career .294 hitter. The average is that high primarily due to one outlier season when he hit .316 in 2015. Add to that the first month of his career, when he hit .156 in May 2014 and it's clearly not time to go into any panic over a .229 average in the early part of the season.
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THIS SUNDAY: Tune into The Progressive Underground as we have an interview with iconic falsetto/R & B crooner Russell Thompkins Jr (pictured middle), lead singer of the legendary Philly Soul group The Stylistics (one of the leading purveyors of the Philly soul movement of the 1970s) in advance of their show next week at Detroit's Fox Theatre. We also interview artist/poet Joel Fluent Greene, who will talk about his latest upcoming event "Love Her, Love Him," an evening of poetry, music and performance happening next week as well. It'll be an evening of deep soulful vibrations and profound thoughtstyle.
The Progressive Underground Show 250 feat. RUSSELL THOMPKINS JR (STYLISTICS) & JOEL FLUENT GREENE
We explore the outer reaches of electronica through techno, deep house, future soul, nu-jazz, b-sides and rare r & b groove.
We also sample tracks from GoGo Penguin, Laurence Guy, Omar, Jamiroquai, The Nonce, J. Lamotta & the Dizzy Sparrow, Crayon, Remi, Sampa the Great, Moodymann, Paul Randolph, Kathy Kosins, Will Sessions, Amp Fiddler, Ideeya, and may more!
The action happens this Sunday, 8-10 pm EST on 101.9 FM WDET and WDET.org.


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Hardhat Digital hosts a monthly speaker event that aims to educate and inspire. May's theme was 'Sex, Drugs & Rock n' Roll' to celebrate their 18th event and 'coming of age'. My talk focussed on the orgasm gap between men and women, and cliteracy 101 – a light hearted introduction to gender inequality in human relationships and sexuality education. You can watch my talk here
Here is the transcript if you prefer to read –
Good morning, before I begin I would first like to acknowledge that we are meeting today on Aboriginal land, the land of the Wurundjeri people of the Kulin nation. And pay my respect to their Elders past, present and emerging. I would also like to preface this talk by saying that I am speaking mainly on issues relevant to cis-gender people, who identify mostly as heterosexual. Cis-gender is a term for people whose gender identity matches the sex that they were assigned at birth. For LGBTQI and non-binary members in the audience, I see you and hear you, and I respect and acknowledge that this is not the experience of all who identify as women. Now, I would like to issue a warning that the following content may contain elements that are not suitable for some audiences. Accordingly, viewer discretion is advised. (Projection of penis graffiti) Can anyone tell me what this is? Yes, that's right, penis graffiti.
We see it everywhere; at the train station, on the walls of toilet cubicles, some of us here are probably guilty of drawing them; on the back of books, on our friend's faces when they pass out at a party… it's common practice. This is of course the male sexual organ and it takes pride of place, front and center. We are so familiar with it, it has become comical. Now can anyone tell me what the female sexual organ is? Ok, I'm hearing vagina? Look you're not entirely wrong… but you're not quite right either. Often female genitalia gets mistakenly referred to as the vagina, when in fact the 'whole package' so to speak is the vulva. (Projection of vulva) Which consists of mons pubis, labia majora, labia minora, the urethra, the vagina and the clitoris. Another mistake we often make is that we refer to the vagina as the primary female sexual organ, and I'm here today to tell you that the hole is not the whole.
Thank you kindly to our none-the-wiser volunteers, who probably wouldn't have put their hand up at this point. (Volunteers are given markers and a white board) I'd like you both to draw an anatomically correct clitoris. (allowing time for activity) Big round of applause for our volunteers, now I'm going to show you what an anatomically correct clitoris looks like. (Projection of clitoris) How is it that we all know how to draw a penis with our eyes closed, and yet for the life of us cannot draw a clitoris – even if we have one!
Did you know that the clit technically wasn't discovered until 1998? By an Australian Urologist named Dr Helen O'Connell, she was the first person to investigate and document the full scope of the organ using MRI. Another fun fact, that same year, Google was founded. Just think how much pleasure Google has brought us in the last 19 years… It's actually astounding that technology has developed faster than our knowledge of our own bodies. The first text message was sent December 3, 1992, by a Canadian engineer named Neil Papworth saying "Merry Christmas". Who else thinks the second one was probably a dick pic? Look don't feel bad, I was ilcliterate once too, it was actually an artwork by Sophia Wallace, called 'Cliteracy', that brought it to my attention in 2013. How did I get to the age of twenty-five and not know integral things about my own body.
This says a lot about the significance of visibility and representation. If male sexuality is the central or only narrative that we see, then what happens to female sexuality? Sigmund Freud, one of the first sexuality theorists of the western world is famous for saying that orgasms from clitoral stimulation were infantile and that vaginal orgasms from penetration meant that a woman was more mature. This has perpetuated the myth that women have the best orgasms from vaginal penetration, when in actuality the clitoris is where that pleasure comes from. Studies have shown that women whose clit is within two centimeters of their urethra are more likely to orgasm from vaginal penetration, though it's not a sure thing, keep in mind this pleasure is still derived from the clit, it's a matter of proximity. This means that anyone's body that deviates from that very specific make-up will not orgasm from penetration alone. This is not dysfunction, this is human.
We live in a world where heterosexual – penis in vagina – penetrative sex, is the central narrative, where sex ends when the man has an orgasm, where male sexuality is celebrated and visible to the point that it is comical. We live in a world where female bodies are deemed a mystery and their orgasms 'elusive', and if they are unable to orgasm from penetration they are seen as dysfunctional. This has created an orgasm gap between men and women. A study conducted at Chapman University in the US, with a sample size of over 52,000 revealed that only 65% of hetero women orgasm during sex, compared to 95% of hetero men. That's a 30% difference, which is larger than the currently reported gender pay gap – talk about equal pay for equal work.
We have clung to Freud's idea of sex and sexuality and this is most evident in mainstream porn and Hollywood. How often do we see a woman moaning in ecstasy after being touched for approximately seven seconds? Or couples climaxing at the same time, every time? It's no wonder 80% of women fake orgasm. And it's not just women, some men do too. A small study was conducted in the US that showed 30% of men had at one time or another faked orgasm in order to 'appear normal'. Where are people getting this sense of normal? It's not just movies and television, it's in advertising, it's online… Pornhub – arguably the world's most popular free porn site, reported 64 million visits per day, with women making up a third of that population. It is becoming more popular for all genders every year and it is increasingly accessible.
Given that we all lead such digitally full lives and almost everyone has a smartphone within 2 cm at all times, we now have greater access to porn, and that access contributes to its popularity. This is clearly influencing our perception of what sex is like and how we think it should be. I'm not here to have an opinion on porn or Hollywood (next time), but rather encourage you to consider what our consumption of these narratives is doing to us. Porn is essentially adult entertainment – just like drinking at a bar or smoking. And just like these regulated adult activities, children will try to consume them before they are ready and legal. 64% of children aged between 11 and 16 are reported to have seen pornography in some capacity. Unfortunately this is their first introduction to sex, before having a conversation about it, before any education, and before they know their own bodies and own desires.
We are looking at a future that has all the tools and technology to stimulate, enhance, advance and excite, all in the name of having better sex. But will this really be the case if 80% of women and 30% of men continue to fake orgasm, and still fail to recognise cis-women's primary sexual organ? In this situation we can't just fake it till we make it. So what needs to happen in order for us to catch up with technology and really reap the benefits? Maybe it's not a case of moving forward, but rather getting back to basics. This means talking more about sex, and not in a glossy Hollywood or Cosmo Mag kind of way. We need to have real conversations about real sex – including bad sex. We need to check in with one another, ask what feels good, what doesn't. This may be uncomfortable at first, but at least we are working towards something authentic. No more faking.
We need to stop thinking about sex as penetrative, penis in vagina intercourse that ends when the man cums. This may mean engaging in or exploring alternative sexual activity. On a more social level I believe we need to be educated on our bodies earlier, and allowed our own desires, free from shame. We need broader representation of sexuality in the media, especially those that celebrate women's sexuality and prioritizes pleasure. And above all else, we need to get cliterate. Next time someone refers to the vulva as vagina, I dare you to correct them, and next time you see penis graffiti, I want you to stop and spare a thought for the clit. The part of women's bodies that goes mostly unseen, and generates the most pleasure.


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Alicia Chang
LOS ANGELES: Neil Armstrong inspired millions with his moonwalk. Can a feisty robotic rover exploring Mars do the same for another generation? With manned missions beyond the International Space Station on hold, the spotlight has turned on machines.
While it did not rise to Armstrong�s �one small step for man, one giant leap for mankind,� interest was so high in the rover Curiosity�s �seven minutes of terror� approach to the red planet this month that NASA�s website crashed. The rover last week beamed home photographs of its first wheel tracks on the Martian soil since its daredevil landing.
�There�s something exciting about reaching another place in the solar system. If you think about the kind of interest the landing of Curiosity had, you get a sense of that,� said Smithsonian Institution space curator Roger Launius.
It wasn�t on the same level as Armstrong�s feat, �but it was pretty darn exciting,� he said.
When Armstrong, then fellow astronaut Buzz Aldrin, stepped onto the moon on July 20, 1969, an estimated 600 million people watched and listened. �Virtually the entire world took that memorable journey with us,� Aldrin recalled after Armstrong�s death on Saturday.
Early in the Space Age, the Mercury, Gemini and Apollo astronauts were the public face of NASA�s space endeavor while the unmanned lunar missions that paved the way were in the shadows. The public craved adventure and the manned missions delivered. Aiming for the moon was new and exciting � not to mention dangerous � and the U.S. was locked in a Cold War space race with the Soviets.
Next, the space shuttle ferried a new crop of astronauts to low-Earth orbit, but after three decades of service, it became routine. And the Cold War thawed with the Russians and Americans cooperating on the Russian space station Mir and the International Space Station.
With the space shuttle fleet retired, the space station is all that�s left. Its crew of six for the most part quietly goes about doing its job about 250 miles above the Earth. President Barack Obama nixed plans for returning astronauts to the moon in favor of landing on an asteroid and eventually Mars.
These days, space exploration is carried out by robotic spacecraft � commanded by human handlers on Earth. Advances in technology have allowed unmanned spacecraft to go farther and peer deeper, with craft circling Mercury, Saturn, asteroid Vesta and others headed for Jupiter and dwarf planet Pluto. The twin Voyager craft are still going strong at the fringes of the solar system 35 years after their launch in 1977.
American University space policy analyst Howard McCurdy said today�s generation of explorers was raised on technology and tends to get more jazzed about delivering a car-size rover to Mars.
�Robotic exploration has taken more of a center stage,� he said. �It gets more publicity now than the International Space Station.�
When the first Mars rover Sojourner landed in 1997, science fiction writer Arthur C. Clarke rephrased Armstrong�s famous line and said the event was �one small step for the rover.�
Three other rovers have followed, including Curiosity, which landed Aug. 5 by executing an intricate routine that ended with it being lowered by cables to the surface.
Curiosity chief scientist John Grotzinger said Monday the wheel prints on Mars may turn out to be an iconic image just like those first boot prints on the lunar surface.
�Instead of a human, it�s a robot pretty much doing the same thing,� he said.


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Also found in: Thesaurus, Medical, Encyclopedia.
in·nate(ĭ-nāt′, ĭn′āt′)
a. Existing naturally or by heredity rather than being learned through experience: "Chimpanzees show an innate distrust of contact with strangers" (Cindy Engel).
b. Of or produced by the mind rather than learned through experience: an innate knowledge of right and wrong.
2. Possessed as an essential characteristic; inherent: "As the Army and farmers built more and more levees, the Missouri lost an innate capacity to absorb its frequent excesses" (William Least Heat-Moon).
[Middle English innat, from Latin innātus, past participle of innāscī, to be born in : in-, in; see in-2 + nāscī, to be born; see genə- in Indo-European roots.]
in·nate′ly adv.
in·nate′ness n.
ThesaurusAntonymsRelated WordsSynonymsLegend:
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|innateness - the quality of being innate
unchangeability, unchangeableness, unchangingness, changelessness - the quality of being unchangeable; having a marked tendency to remain unchanged


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Hot on the heels of the international reveal of the BMW X7, pricing has appeared on the BMW South Africa website. Here's how much the biggest X costs.
After seeing the BMW X7 iPerformance concept, it was only a matter of time before a production X7 was revealed. Built alongside the X3, X4, X5 and X6 at BMW's plan in Spartanburg, South Carolina, the BMW X7 is a lot bigger than you'd think. It boasts 7 seats and is 5 151 mm in length, 2 000 mm wide and 1 805 mm tall, and has a wheelbase of 3 105 mm. BMW claims that these are the largest kidney grilles ever.
The X7 also features large wheels. The standard units are of the 20-inch variety, while you can option 21- and 22-inch wheels. BMW has fitted the new X7 with a smart xDrive system which can send 100% power to the rear axle.
The price for the South African-spec BMW X7 was discovered on the BMW SA website and we can confirm that we're getting the two diesel models. The xDrive 30d has 195 kW and 620 Nm from a 3.0-litre inline 6 cylinder motor, while the M50d Performance pushes out 294 kW and 760 Nm from a quad-turbo 3.0-litre inline 6-cylinder. Both vehicles feature all-wheel drive and an 8-speed automatic transmission. The 30d is said to consume 7.0 L/100 km and emit 192 g/km, while the M50d is said to use 7.3 L / 100 km, with CO2 emissions rated at 192 g/km.
Further Reading
Meet the new BMW X7
BMW X7 iPerformance Concept Revealed
BMW X7 Price in South Africa
BMW X7 xDrive30d SAV R1 562 849
BMW X7 M50d SAV R1 862 308


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Available ebook formats: epub mobi pdf rtf lrf pdb txt html
After a long career working with books - first as a buyer for a national retail book chain, then as a production associate publishing leather-bound classic books, I decided to use my creative energy to actually write some books! My kids were a great inspiration.
I wrote my first book, The Forgotten Isle, in 2003, and then started many projects, and never finished any of them. I finally finished and published The Forgotten Isle with illustrations by Noa Chaikin in 2011.
The concept for "Into the Outside" (which began life with working title "Out of Ewr") has been around since about 2005, and the novels have been floating around in my head since then. The first "Into the Outside" short story was released on Kindle in Nov. 2013, and the full length novel to follow later in 2014.
I currently belong to a Writer's Group in northern Vermont, and I'd like to thank them all for their invaluable critiques. I wouldn't know what to do without them! And my sincerest thanks go to my best friend/editor/co-writer/bounce-off-the-wall-all-things-important-and-not-important (I'm not sure exactly what to call him) but I couldn't do any of this without him, Henry Dixon.


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ZOO Magazine 59 – Summer Issue. On this cover Agnes Nieske Abma in a Prada FW 18 Special photographed by Nagi Sakai
ZOO Magazine 59 – Summer Issue. ZOO Magazine 59 delivers 5 covers featuring dancer Sergei Polunin photographed by Roger Rich, Agnes Nieske Abma in a Prada FW18 Special as shot by Nagi Sakai, Alyssa Traoré in a denim special by Alex Cayley and Daniel Desmarais in a Louis Vuitton special by Nik Hartley.
Other stories in this issue include an interview with Angela Missoni, an interview with Charlotte Macaux-Perelman and Alexis Fabry, Creative Directors of Hermès Maison Universe, a portfolio by and interview with Wim Wenders, Marie Ange-Casta in a special Longchamp shoot by Ricardo Gomes, a fashion story with Querelle Jansen by Thomas Schenk, Actress Hanna Hilsdorf showcasing Chanel's Métiers d'Art Paris-Hamburg collection in a shoot by Roman Goebel, a special portfolio by Swip Stolk, an interview with artist David Claerbout and an interview with Olivier Audemars, Vice President of Audemars Piguet's Board of Directors, and the British artist duo Semiconductor, who were selected to create the fourth Audemars Piguet Art Commission as well as a Salone Special featuring the latests interior and design.
Note that the covers of this issue will be selected at random when ordered. At the end of the Checkout you can note which cover you prefer, so we can send the right one.


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I figured that since I'd sold my firstborn to buy my race photos, I'd better do something with them. So here they are:
Out of the swim. Note the "Here is my race number" pose? This is how to make sure you get your swim-exit photos! SIGH. My debut race, yet so onto it. This was the first indication of the awesomeness to come. Also, possibly the only time I've ever managed to raise just one eyebrow. Completing the Ironman kinda pales into insignificance really…
Cornering in the rain. Actually, I just wanted to show off the flash new helmet they made me buy because my one was cracked! Alert readers will recognise the IMTalk jersey which I didn't get to show off due to the rain.
Tongue action. Look, it was so wet that I had to concentrate even on the straight roads! Two fingers on the rear brake this time – disappointed I didn't have at least one on the front. Further proof that I can take it up another level!
Dancing girls. Yeah, that's the first thing I noticed in this photo too! Shame I didn't notice them on the day. End of the first lap and I was hurting bad from the stitch about now – not that I can tell from this photo. Clearly I cry on the inside…
I won! That's right. You thought Cameron Brown won Ironman New Zealand 2011 didn't you? Well, if you look close you can see him despairing behind me as I crossed the line for my first Ironman victory. See, I've even got the "I am number 1" fingers going and all (my sponsors got really mad at me for not holding the tape above my head though).
Could I also be the first guy anywhere in the world to win an Ironman – in a rain jacket?


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Review Details
Coca-Cola Share a Vend
- Product Review (submitted on February 18, 2019):
- I placed two vend orders. The first one showed up in my Apple Wallet as soon as I added the Coke pass card. The credit for the second vend did not show up despite the fact that I received an e-mail confirmation of the order and a text confirmation on the phone it was sent to. It was my understanding that if a Coke pass card was already set up additional credits should show up automatically. This did not work for me. I called the helpdesk and someone is supposed to contact me within two business days.


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Landlords house insurance protects you against unwanted mishaps, but it is important to remember that you do have some legal obligations for all of your properties. This is to safeguard the wellbeing of your tenants and to ensure that the properties you lease remain in a tenable position. In this post, we are going to briefly review the things you are obliged to do with regards to gas and electrical appliances.
First of all, you need to ensure that you keep a track of the gas and electricity usage in your household. All of the gas-based appliances must be verified for safety purposes every 12 months, and they must be maintained in between these checks. You need to keep all gas-related records for two years, and when a tenancy ends, you must do a brand-new check of the property's appliances before re-leasing.
Ensuring that every electrical product or appliance is not defective is a vital part of your job as a landlord, and landlords house insurance may not cover you should you not fulfil your responsibilities. Make sure you keep track of all of the times you monitor the electrical products, and if you discover that there are defective or faulty products, make sure that they are removed from the house straight away. This will ensure that the safety of your tenants comes first. Some of the time, your landlords house insurance will cover the cost of replacements if you make a claim.
With being a landlord comes responsibilities, and to guarantee that you have satisfied tenants who will always want to remain in your property and renew their agreements, make sure that you look after your property. Being a landlord is an investment, and by fulfilling your duties, you could benefit financially and prevent the need to use your insurance and pay an excess.


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3886 23RD AVENUE, Vancouver West, BCMLS®#: R2165012
Listing Overview
- Property Value$4,588,000
- Property Address3886 23RD AVENUE, Vancouver West, BC, V6S 1K9, Ca
- TypeHouse
- Style2 Storey w/Bsmt.
- BasementFull, Fully Finished
- Year Built2017
- Taxes$7,536.03
- Living Area2,918 sq.ft.
- Lot Depth122 ft
- Lot Size Area4,026 sq.ft.
- Bedrooms4
- Bathrooms6 full
- Maintenance Fee$0.00
3886 23RD AVENUE, Vancouver West, BC, V6S 1K9, Ca
Brand new custom built home! Located in famous location "Dunbar"! Spacious & bright open layout. Features 3 ensuite bedrooms upstairs. Chef's kitchen including a wok kitchen/island/all Miele appliances/white cabinetry/solid wood doors/top-of-the-line silestone countertops, spa-like bathrooms with luxurious finishes. Basement features recreation room, home theatre & 1 bedroom. Conveniently close to Dunbar shopping, retail, community centre & UBC. Lord Byng Secondary, QE Elementary, St George's, immaculate school close by. Don't miss out! Open House: Sun, May 21, 2-4pm
Listing Provided By
Royal Pacific Realty Corp.
Copyright and Disclaimer
The data relating to real estate on this web site comes in part from the MLS Reciprocity program of the Real Estate Board of Greater Vancouver. Real estate listings held by participating real estate firms are marked with the MLSR logo and detailed information about the listing includes the name of the listing agent. This representation is based in whole or part on data generated by the Real Estate Board of Greater Vancouver which assumes no responsibility for its accuracy. The materials contained on this page may not be reproduced without the express written consent of the Real Estate Board of Greater Vancouver. Copyright 2019 by the Real Estate Board of Greater Vancouver, Fraser Valley Real Estate Board, Chilliwack and District Real Estate Board, BC Northern Real Estate Board, and Kootenay Real Estate Board. All Rights Reserved.
- Sarina Han
- Mobile: 778-882-0099
- Office Phone: (604) 730-1111
- Email: firstname.lastname@example.com
- Luxmore Realty
- 3076 Arbutus St
- Vancouver, BC


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Refining and Petrochemical
Transform the oil in clean and valuable products through a set of physicochemical processes, taking advantage of synergies, ensuring profitability and aligned to the strategic framework of Ecopetrol SA
Add more value to Ecopetrol's raw materials available and identify opportunities for growth and market-based through a set of physicochemical processes, exploiting synergies, ensuring returns for the Petrochemical business, assure the integrity of persons, environment, infrastructure, quality and secure information management.
There are currently no open positions matching this category or location.
Receive emails by subscribing to jobs matching Refining and Petrochemical when they are posted.
The 0 most recent jobs posted by Ecopetrol are listed below for your convenience.


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As a first-time business owner, it's easy to get caught up in the hype when it comes to creating elaborate product copy or simplistic navigation. Although these website features are some of the most crucial elements of your online presence, supporting pages like your "About Us" section serves a key purpose when it comes to branding, attracting a target audience and creating a sense of trust within the industry. Whether you use this section to write the entire history of your company, talk about your mission as a business owner or simply just state what your service stands for, when a visitor wants insight into your professional ventures, this should be the page that they can utilize to answer their questions.
What the About Us page is for?
Your "About Us" page is the space for your founding story and it's also a place for you to show off your business achievements. While many business owners bury their "About Us" page within a random footer at the bottom of their website, others simply write a few poor paragraphs talking about the origin company. Needless to say, this profound section of your website should be best reserved to talk about the business and highlight the biggest selling points of your story and brand. So, that being said, why not wow your customers by making a strong impression?
Here are some examples of what you could include:
- The story of your business and why you started it.
- Discuss how your business best serves its clientele.
- Talk about how your products are made.
- Feature some information on all the members of your team in order to put a face to your business.
How should you structure your "About Us" page?
If your goal is to set the stage with your branding, your "About Us" page needs to have compelling storytelling. Here are some tips that you can use to craft a narrative that's both professional and effortless to read.
- Set the scene by introducing yourself to your audience. Make sure to include how long you've been in business, where your inspiration came from and talk a little about how your product or service fits into the industry.
- Describe the industry problem that encouraged you to take action.
- Talk a little about the obstacles that you crossed. This adds some insight into your journey as a business owner.
- Talk about your future goals. What do you hope to achieve as your company grows?
Do you need help getting your web design started? Aside from creating your "About Us" page we're equipped with the skill and knowledge to develop a variety of plugins and installation upgrades on your e-commerce platform
What is your favorite element in the "About Us" space of a website? Drop a comment below to share your thoughts.
Alex Wilks is the Social Media & Content Creator for Trek Marketing. Her work has been featured on Global News, Black Press Media, andthe Kwantlen Chronicle


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The Fountain
Looking Back
October 12, 2011
Read More
October 12, 2011
One of the few universally loved showmen in Hollywood, Hugh Jackman has maintained his humble attitude and Aussie charm every step up his career ladder. Audiences love him whether he's slicing up bad guys as Wolverine or hoofing it in Broadway musicals like Oklahoma and The Boy from Oz. Snakkle takes a look at the varied path Hugh's taken to international fame.
Read More


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Scoffing aside for a while, the RDS isn't cheap. Whos bankrolling this? pic.twitter.com/P7RsCPrZYm
— Gerard Cunningham (@faduda) December 18, 2017
Scoffing aside for a while, the RDS isn't cheap. Whos bankrolling this? pic.twitter.com/P7RsCPrZYm
— Gerard Cunningham (@faduda) December 18, 2017
Nigel Farage? Wasn't he blown out into space and killed in the latest Star Wars Movie?
No, he's actually Voldemort.
You have to kill him seven times to be sure he's actually gone.
They blasted him off into space in a one man prison vessel. But it was revealed they had accidentally placed a foreigner on board by mistake. Spokesperson said: "This is the one thing we didn't want to happen."
Of three of first three speakers there, I see three visions for Ireland:
-The best little tax haven in which to do business,
-Confessional vassal of Rome,
-Quasi-independent vassal of Britain.
lolz @ url
Amusingly it's free but ticketed event. The more nefarious of you could book 2/4/6/8 tickets each…
By 'you' I mean, us.
Limited to 2 per head
and this
This event is sponsored by the EFDD Group in the European Parliament and is open only to supporters of a Irish Exit from the European Union. Unwelcome interjections from the audience may result in removal from the event.
One way around that is for loads of people to book two tickets each, and then not turn up. That way, you're not in breach of their rules about interjections, and they look like idiots speaking in front of an almost empty RDS hall.
What is the "Nationality Crisis"?
Code for too many migrants probably.
A foreigner telling us we've too many foreigners? Oh the ironing!
needs more starch…
Give ya a stiff upper lip that!
Poor oul Nige needs the money. he is broke after All. #Nigeaid
Oooooh,an outsider.He's not one of us.
I expect if John Waters is an outsider it's due to him being increasingly out of step with a new generation disaffected by and disenchanted with the Catholic Church and its more conservative teachings, not to mention its mistreatment and exploitation of vulnerable women and its protection of sexual predators. He really should try to be more understanding of that point of view, or he'll only become increasingly bitter at his marginalisation. Not sure embracing a radical far-right project fueled by xenophobia and isolationism will help with that, though.
Charger joins in, but so weakly, it's like the fights gone out of him, poor lamb.
Ha yeh Brexit is going so smoothly for Britain thus far, and it's clearly going to transport their economy into the major nations stratosphere. We would be mad not to do the same!
Oh wait, no….
*clutches EU passport close*
If John Waters is for it, then I'm against it
Terms and conditions:
"This event is sponsored by the EFDD Group in the European Parliament and is open only to supporters of a Irish Exit from the European Union. Unwelcome interjections from the audience may result in removal from the event."
(and WAS IT FOR THIS?: "For international customers based outside of the United Kingdom or to enter your address manually, click here.")
This will be the greatest event ever staged. Personally, I hope it's a tremendous success and the lads have a ball.
Just like the real brexit, the best guys are it, it's going to be AMAZING!
When the squeeze is put on and a common tax rate imposed at the behest of the French (who have done nothing to reform their own economy) I can see the calls for Irexit then.
It wasn't that long ago when the EU were the bad guy in Irish eyes.
Nobody can impose a common EU tax rate without the unanimous agreement of all EU member states – which, of course, wouldn't be imposing anything. I wouldn't hold my breath.
Don't hold your breath then Alastair but this will happen.
Wouldn't it be terrible if we all booked tickets and then didn't show up?
Ha, ha, ha. See they left the .co.uk out of the URL for tickets? Hiding the "Ireland will be a province once again" thinking of the Brexiteers? Also, this is from the ticket booking site:
"This event is sponsored by the EFDD Group in the European Parliament and is open only to supporters of a Irish Exit from the European Union. Unwelcome interjections from the audience may result in removal from the event."
Not sure how to pronounce thay. Doesn't quite roll off the tongue like 'Brexit'. Reckon that's the only reason UK went ahead with it- came up with the name and decided it was too good not to use.
It's not on the RDS website. Are they waiting to see what kind of uptake they get on the tickets before booking a room?
will there be light refreshments
April fools is early this year
Why scoff? Seriously the EU is not a benevolent organisation, they royally screwed us over when the banking crisis hit, and Greece's democratic reform was greeted with a "so-what? F.upp you – pay us" attitude. The Lisbon treaty was anything but democratic. Do I think we should leave the single market? Nope. Do I think the ever growing EU superstate could use some public debate? Yes I f.upping do and you're a sheep or worse if you make fun of those that do.
I would say everyone agrees with you on that point, curmudgeon.
It is the involvement of the likes of John Waters that I personally am scoffing at.
I agree that the EU suffers from a number of grave systemic structural problems that ought to be debated much more widely than is currently the case.
You ask, "why scoff?"
The answer to that is that this is an event bankrolled by Europe of Freedom and Democracy, an EU parliamentary group comprised of known racists, buffoons and neo-fascists and that at least two of the headline speakers are widely regarded as dangerous, objectionable clowns.
Scoff away.
They scoff because they have short memories.
Once Brexit is concluded and the compliant Irish have served their purpose and been tossed aside liked a used condom France and Germany will come after Corporation tax and tax havens.
And with Blighty's €10billion a year annual payments gone the net contributors, of which Ireland is finally one, will have to pony up plenty more moolah to cover the shortfall.
And all the while 20,000+ immigrants quietly flood into the country every year looking for housing,places in schools and free medical cards and suddenly Patrick wakes up to a very different country.
Great – can't wait for more immigrants to freshen up the gene pool and rid us of the vestiges of lace curtain west britishism and brutal, papist peasantry
As for this: " France and Germany will come after Corporation tax and tax havens." – great as well, about fupping time , who knows we might even be able to find some more social housing then or a proper health service
You people are xenophobic racist scum btw
"Great – can't wait for more immigrants to freshen up the gene pool and rid us of the vestiges of lace curtain west britishism and brutal, papist peasantry "
You forgot to mention the cuisine.
What utter clichéd nonsense.
I have a friend who is an anthropologist who would agree with you except the latest wave is gay Brazilians. Never behind the door when looks were being given out but hardly likely to be stretching the local primary school's resources anytime soon?
€10 bn off set by the €6.5bn the UK receives in funding from the EU no longer being paid out.
20,000 + immigrants that the UK has agreed to retain citizenship rights for.
Other than that, spot on mate.
Once Brexit is concluded. It will be concluded alright, into the dustbin of history.
Them and us doesn't work here sweetheart, we already have the 'howaya' blacks and the 'howaya' asians so it's only a matter of time before we have the 'howaya' Muslims too. Problem yours not theirs partner. Comperende?
+1 curmudgeon
where's Charger anyways? kinda missing the pub landlord. too busy fixing leaks on HMS Brexit innit?
From the BBC:
" The fault on the £3.1bn carrier was first identified during sea trials.
A Royal Navy spokesman said the ship was scheduled for repair and the fault did not prevent it from sailing again early in the new year. "
The clue is in the first line.
Oh, Charger, even lame horses get put down. See, it's getting embarrassing now, watching you squirm.
Thanks Broadsheet for highlighting this Event, just booked my tickets, can't wait 'til February!
Bankrolling, you ask? Probably the same international poo-stirrers who paid the intellectuals in the DUP £425,000 to push for a Brexit, comically contrary to their own obvious economic interests and endangering the economy in the rest of Ireland..
Freedom to prosper, if you're a business and keen on the idea of removing work hour limits, paid holidays and all that health and safety nonsense that is.
An opinion poll in May said that 88% of us are happy in the EU. Brexit gets more and more shambolic every day. Ireland has secured legally binding agreements on there being no hard border. What makes these goons think there's any appetite for self destruction here?
No thanks, I'll keep my paid holidays, Nige.
I find it heartening that the only Irish elected official that they could find to speak at their event is a local councillor that no-one has heard of.
It's the fear generated by the appearance of Nigel Farage in their midst that has Paddy up on his hind legs mewling and gibbering.
The very thought that someone with a different political view might wish to engage them in debate sends them off into paroxysms of angst.
" Ooooooooh,how very dare he.Let's get tickets surreptitiously and go along to disrupt the meeting and stamp our feet. "
Kevin Myers was right last night.The liberal bottom-sniffers hate anything that offends their politically correct and consensual norm.
Amazing how disagreement sends people like Salmon and Myers into spasms of insult and high dudgeon. We're not obliged to like you or your appalling opinions. We're not obliged to disguise our revulsion. Stop whinging. Your political views needed years of hateful lies blazed across tabloid front pages and about a million Russian bots and a delusion of utter disbelief in the sensible part of the UK electorate that anyone could be this stupid. Now you represent the Brexit point of view with endless stream of racist abuse. What a salesman for Brexit you are.
Brexit relied on lies and racism to get the vote so it should come as no surprise that racism is part and parcel of their rhetoric.
I certainly don't view Nigel the Nazi's intention to speak in Ireland with fear. If anything it's with incredulity at his brass neck and wry humour that a man so blatantly racist and hypocritical thinks he'll have an audience for his snake oil in a country that was used and abused by his own for generations. No doubt he'll get an evening on the Late Late though .
Curious thing here is that – yes, whisper it – I would actually be interested in Charger's response to this IF there was any chance he could or would present a reasoned, intelligent one.
Unfortunately, though, he will either 1) ignore it and stay quiet for a while only to pop up on another thread altogether and just repeat the same old hyperbole mixed with racist and childish insults, or 2) respond but ignoring the points, instead monkey-mocking a typo or whatever + a mix of childish and racist insults.
Would you perhaps take this as a challenge, Charger? Could you? Genuinely – are you capable of engaging in intelligent debate? And that does mean leaving your boorishness, childishness and racism to the side for a moment. And actually presenting intelligent argument.
Can you do that?
You're asking a pig not to snort.
Leather Jacket Guy effectively disappeared once we stopped giving him the oxygen of attention, perhaps we should do the same with Charger, he's clearly just looking for any attention, good or bad.
The Broadsheet regulars' collective decision to completely ignore LJG once enough vitriol had been poured forth (and the extraordinarily creepy legion of fake accounts went quiet) was a thing of great beauty.
If there's one thing we Irish can do it's a boycott :)
@Nigel (the snowflake and not " the most successful politician of his generation " )
Ah,the old " Russian bots persuaded 17.4 people to vote Leave against their will " nonsense that you keep peddling.
I don't suppose you subscribe to the Continuity Remaining Financial Times otherwise you would have seen their story this morning rubbishing such claims.
Researchers at Oxford University found that just 105 Russia-linked accounts tweeted in the run up to the vote and that there was no "significant Russian activity" during the referendum.
Twitter said only one Russian account spent any money promoting tweets during the referendum, and they only bought six adverts.
It emerged that most Russian Twitter activity about Brexit actually took place after the referendum.
And a number of the Russia-linked Twitter accounts were actually pro-Remain.
Google told the Electoral Commission it had found no evidence of any paid Russian activity during the referendum.
Facebook said Russia spent a total of 73p on adverts during the referendum, and they reached 200 people.
Researchers even found that one account accused by pro-Remainers of being a Russian troll turned out to be run by a security guard in Glasgow.
Doh !
You need to get your news from somewhere other than the RTE/Irish Times/Guardian axis of effluent.
Hey, since we agree about the endless tabloid lies and the racism, I won't argue the point, though even if true you should be ashamed that since you were so easily persuaded by the latter the Russian bot army barely bothered to show up.
Stop digging old cock.
Another one of your spurious claims has found to be hogwash.
Well according to you, oh trustworthy one. But not the lies and the racism.
Racism you say ?
You're right,I say.
What, you think Irish racism can be exploited to push for Irexit? That is certainly a bit of a worry, particularly with support from Brexit racists like yourself. Hopefully the rest of us will have learned a lesson from the dangerous complacency of non-racists in the UK.
By the way, you must be very proud of your own efforts in getting the levels of racism in Ireland up. Congrats!
I'm sure the bearded hipster types at Broadsheet Towers have a zero tolerance towards racist postings.
Otherwise why would I still be here ?
But it's an easy trope for sandalistas like yourself to trot out.
It's the default raised handbags position of the intolerant Left.
Most pathetic counter argument of the year award
It is easy to trot out the argument that you are racist because you are literally and obviously racist. You can't even argue coherently that you're not, and you'll say anything. Am I intolerant of your racism? Aw diddums.
Now you're floundering like a fish out of water old sport.
Step away from the keyboard,take a deep breath and perhaps go and make yourself a cup of camomile tea to calm yourself down.
Because at the moment you're making a tit out of yourself simply because I produced evidence which knocked one of your arguments into a cocked hat.
Seriously,you can shout wacist,wacist,wacist and stamp your feet as long as you like but it won't undo the evidence above.
I'm off for a while anyway – Christmas scoops with chums including my Slovakian gardener this arvo.
Pip pip !
Bye, racist!
I remember something. Monday 13th November. A very strong speech specifically accusing Russia and Putin of seeking to "undermine free societies" and "sow discord" in the West by "deploying its state-run media organizations to plant fake stories."
Theresa May.
Probably nothing.
Last I heard Facebook and Twitter were not Russian state-run media organisations.
But hey,if the cap fits you wear it lovey.
I dunno darling, after the Russians helped bail you out in WWII, I thought you'd welcome their help again in your pursuit of independence.
Not rewriting history again are we petal?
My personal favorite is when duchesses who purvey fake news buttress their point with other equally fake news sources
Wow, ouch. Your responses usually have a glibness that disguises their wrongness or dishonesty, but you must be off balance because that's about three blatantly stupid responses in a row. Or maybe your schtick is running on empty.
D'ya know wha' Sammy
The only thing about Farage that creeps me out is his Farah slacks and gold tone buttoned blazers
And my biggest fear about being in his near company is discovering that the arse on those slacks is shiney
So the Event Terms and Conditions:
"This event is sponsored by the EFDD Group in the European Parliament and is open only to supporters of a Irish Exit from the European Union. Unwelcome interjections from the audience may result in removal from the event."
So they obviously don't want to 'engage in debate' and hear opposing views – just more racist and xenophobic rabble rousing from the far right.
This YouTube video is posted on a channel called SkySA, which boasts other such charming gems as:
– Did Jews alter our Modern Bible in order to deny Christ, and to exaggerate their victimhood?
– 1,000,000 British Children Raped by Muslim Men! – This is Institutional Ethnic Cleansing!
– The Man who refused a photo with mandela!
– Why the dismantling of Apartheid has caused the destruction of Black South Africa and genocide of White South Africans
– European Leaders and MSM Must Hang! Proof Refugee Crisis is a Sham
Let's not even begin to pretend this event isn't fuelled by racism and xenophobia.
Oul' Sammy there must be as horny as a Hogget Ram
Oh.. it's that John Waters… I was gonna say, the new "I'll bleedin' recks it " campaign might be interesting with a cult film director on-board… shame..
I used to like the fact that farage had the balls to stand up to the beaurocracy that's been corrupted by financial elites at the heart of the EU and then it all went totally fruity and nutty within a year or two.
The main reason for Brexit was the political class in britain allowing a referendum in the first place. Our constitution is better suited to having a referendum but for britain it should have been debated properly and decided upon through parliament.
Everyone involved used the issue as a political football or a stick to beat the usual polemics of left vs the right, millenials vs baby boomers, liberal vs conservative etc. etc. and vice versa.
Added to that, the tory's are still living in the past thinking they are keeping the jolly old empire alive and deserve to be prioritised before the EU member states as a whole. Drop bojo the clown argueing against Labour( Tory light ) in the middle and good luck making sense of it… let alone not expecting every mad idea to burst out of the woodwork.
All this nonsense about russian hackers and putin is hilarious to read. US NSA, UK GSOC, RUS FSB, GER, FRA, CHINA, ISRAEL many other security services and a load of random hackers are all over your phones and devices right now and have been for years pretty much all of the time or anytime they like. The mad notion that it's only rus trying to intefere with the US and EU is hilarious, it's like Reagan whining about reds under your bed from the 50's in the middle of the mccarthy tribunals..
Just in case you haven't heard and you don't know… there's a new cold war that's been going on for almost twenty years at this point, you just can't see it and it's not reported in the news. Everyone is hacking everyone else you daft propaganda victims.
Anyway, the pope-a-dope vs the abortion referendum and more of all this madness will make for a fun year ahead….
What a bunch of gobs***s, just the fact that they included farage shows how clueless they are.
I might actually go to this. At worst I'll walk away thinking I have wasted some time. The 'working man down the pub' Farage is entertaining; especially when he tries to defend British top tier corruption with things like this.
I like how it's framed as having literally nothing to do with his beliefs. It is only to do with his repellent opinions but that's how people like him duck direct criticism.
Someone thinks its a good idea to put waters and farage in the same building in a nation thats full of people that hate them both, what could possibly go wrong? I am fully sure anti europe friend of farage, enda sherlock will be their and renua too, one would almost think that this would be the sort of gathering that someone who wished to send a message that these people are not welcome to spread hate would have to attend.
There are two ways to end a relationship. The not-so-clever way is for you to break up with the other. Unfortunately, the other will most likely resent you and also may not accept the breakup and continue to harass you.
The cleverer way is to annoy of your other half so much that they dump you!
The UK is doing it the first way. Meanwhile, Poland is doing it the other way. Poland is making the EU kick them out. Much simpler and more effective.


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- Homepage
- A Modern State
Nexio: leveraging digital technology in support of energy transition24 February 2020 News flash
Marie-Pierre Gramaglia, Minister of Public Works, the Environment and Urban Development, Thomas Battaglione, Director and CEO of SMEG, and Pierre Weill, Deployment Manager for Nexio, held a press c...Read more of Nexio: leveraging digital technology in support of energy transition
Visit by H.S.H. Prince Albert II to Mountain View Yesterday04 February 2020 News flash
H.S.H. the Sovereign Prince, accompanied by a Monegasque delegation, visited the MountainView site yesterday to meet Google executives, discuss possible areas of collaboration with the Principality...Read more of Visit by H.S.H. Prince Albert II to Mountain View Yesterday
The First Annual Activity Report of the Women's Rights Committee Has Just Been Published04 December 2019 News flash
The Women's Rights Committee has just published its first annual activity report. This report was presented at the Committee's second plenary meeting, which took place on Tuesday3December 2019 at t...Read more of The First Annual Activity Report of the Women's Rights Committee Has Just Been Published
Civil aviation in Monaco enters the digital era03 June 2019 News flash
On 3 June, the Civil Aviation Authority and Air Space Drone presented a preview of the FlySafe programme in Monaco. This unmanned traffic management (UTM) system will make it possible, from 17 June...Read more of Civil aviation in Monaco enters the digital era
Extended Monaco: the Monegasque model in a digital world02 May 2019 Press release
On 30 April, the Extended Monaco, Smart Principality programme was presented at the Yacht Club in the presence of H.S.H. Prince Albert II. The Prince's Government delivered its vision of the Princi...Read more of Extended Monaco: the Monegasque model in a digital world
11th IMSEE Scientific Council24 April 2019 Press release
The members of the Scientific Council for Statistics and Economic Studies met this morning at the offices of the Monegasque Institute of Statistics and Economic Studies (IMSEE) for an update on its...Read more of 11th IMSEE Scientific Council
See Monaco in augmented reality with CardMap19 April 2019 Press release
Thanks to close collaboration between Monaco's Tourist and Convention Authority and the company K-Rma tech, visitors can now enjoy an interactive and dynamic way of discovering the Principality wit...Read more of See Monaco in augmented reality with CardMap
The Prince's Government Makes a Commitment to Monaco Telecom With Regard to the Financing of Internet Security Solutions16 April 2019 Press release
This morning, Serge Telle presented Martin Peronnet, Director General of Monaco Telecom, with a letter of intent regarding the financing of Internet security solutions for individuals and professio...Read more of The Prince's Government Makes a Commitment to Monaco Telecom With Regard to the Financing of Internet Security Solutions
The Prince's Government Invests in Training28 February 2019 Press release
Today, the Minister of State inaugurated the Campus, a learning laboratory based at the premises of the Monaco Digital company in Fontvieille, in the presence, among others, of JeanCastellini, Patr...Read more of The Prince's Government Invests in Training
Lionel Galfré joins the DITN; Sophie Vincent Succeeds him as Head of IMSEE04 February 2019 Press release
Lionel Galfré, who has been Director of the Monegasque Institute of Statistics and Economic Studies (IMSEE) since it was founded in 2011, joined the Digital Transition Office (DITN) on 28 January,...Read more of Lionel Galfré joins the DITN; Sophie Vincent Succeeds him as Head of IMSEE
A Modern State
A Country, a State, an Administration, a Community: Modernity to serve excellence and act as an example to all
Monaco is a "modern" country, with its finger on the pulse – exemplary at more than one level.
The Prince's Government wishes to apply this exemplary character to its own Administration, the behaviour of the State and relationships with its users.
H.S.H. the Sovereign Prince has given the Government a very explicit roadmap on modernisation and the Administration, and how to interact with users.
Being modern does not mean being without roots, or turning one's back on experience. A modern State is an exemplary State. A modern Administration is a community of human resources striving for excellence, providing quality of service and nurturing high-quality relationships with all those with whom it is in contact.
The Prince's Government has put in place an ambitious and practical plan to modernise the State
This modernisation, affecting all of the human community involved in serving the public, concerns the management of the civil service. Click here to find out more
Keeping up in modernity has led to the setting up of new e-Government processes and facilitating contact, applications and procedures. It has also involved completely re-examining relationships with users. Click here to find out more
The whole State has been mobilised to work towards eco-responsibility, to be exemplary and to demonstrate that effectiveness is not incompatible with efficiency. Click here to find out more
A modern and responsible State must manage every euro in an exemplary way. In the midst of an international crisis, Monaco is a shining example. Healthy finances, no sovereign debt.
The Constitutional Reserve Fund is managed wisely to ensure the financial independence of the country, whilst still investing in its future. By managing its public finances in a modern way, the Prince's Government will have the resources to maintain the economic, social and sustainable model that defines Monaco. Click here to find out more
This website is an illustration of modernity. Browsing the many aspects of government action gives a measure of the exemplary nature of Monaco, a model country. Beyond its borders, a few clichés still abound. False ideas which are painful for the Monegasque community that is aptly proud of its country. These clichés sometimes mask reality, casting a shadow over the natural attractiveness of the Principality.
Each member of the community is the ambassador of an accurate and renewed image. The Prince's Government has decided to give to Principality additional visibility, by launching a communication campaign that has attracted the attention of the public all over the world. Click here to find out more
- The Extended Monaco digital programme
- Modernising the Administration
- Digital Security: a challenge for the future
- Assessment of public policies
- Protection of personal data
- The Administration's eco-responsibility
- The duty of remembrance
- Public finance – meeting challenges more effectively
- The Public Service
- Monaco's image


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For individuals who wish to invest in a certificate of deposit (CD), there are two methods by which they'll accomplish that, which is to go to a bank or a credit union. It is an financial affiliation actually and what the sellers of these buildings do is title them as a credit union like; ABC Credit Union and sell them for inflated costs as a credit union simply because the Swedes assist you to use credit union within the title, it's nothing like the American Credit Union.
According to the Kehrer examine credit unions have been extra generous than their financial institution counterparts on average using one sales assistant for every 2.6 advisors while banks have an assistant cover a mean of 3.6 advisors. The Swedish Credit Unions would not have financial institution secrecy since they're from Sweden which isn't a privacy jurisdiction.
If one didn't comply they could cancel your corporation or credit score union in case you want to name it such, or worse even going after you personally for fraud, income tax evasion, etc. Regardless of account measurement within the credit score union, every member could run for the volunteer board of administrators and cast a vote in elections. Operating as monetary intermediaries, credit score unions finance its mortgage portfolios with the mobilization of member savings and shares throughout the union, as a substitute of utilizing exterior capital resources. The motive that these members volunteer for this type of place is so that they will have a voice within the everyday workings of the union and so as to shield it's status.
A credit score union's effort to make sure that its members are glad over the long term is rewarded by a rise in income by means of repeat enterprise, referral sales, decreased member maintenance costs, and reduced exposure to price competitors.
The applications are designed to guard customers from writing unhealthy checks or making expenses on their debit or bank cards that are not correctly backed up by a checking account stability. Unions often require that members meet a wide range of eligibility criteria to change into a member, although it is gotten easier to qualify for credit score union membership in recent times. Compared to a bank that are owned by various shareholders, that does not essential belong to the particular financial institution in question. However, there are some key characteristics of credit score unions that draw many people to make the swap.credit union


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Sponsored swim aids Sheerness RNLI
Young swimmers took part in a sponsored swim and presented a cheque to the RNLI.
A group of youngsters aged from nine to 16 years of age from the Beachfields Swimming Squad based on Sheppey raised money for Children In Need and the RNLI by taking part in a sponsored swim at the Mote Park leisure centre in Maidstone.
A cheque for £222.50 was handed over to Sheerness Lifeboat Operations Manager Colin Washford at the lifeboat station on Sunday 10 April. The group were then given a tour of the station and the lifeboats by the volunteer members of the crew.
Lifeboat coxswain Robin Castle said: 'We were very pleased to receive the cheque on behalf of the RNLI and it would be nice to think that amongst the youngsters present we could have some future crew members or lifeguards.'
RNLI media contacts
• Vic Booth RNLI Lifeboat Press Officer (Sheerness) 07926904453 / 01795 880544 firstname.lastname@example.com / email@example.com
• Tim Ash, RNLI Public Relations Manager (London/East/South East) on 0207 6207426, 07785 296252 firstname.lastname@example.com
• James Oxley, RNLI Press Officer (London/East/South East)
0207 6207425 / 07786 668825 firstname.lastname@example.com
• For enquiries outside normal business hours, contact the RNLI duty press officer on 01202 336789
Key facts about the RNLI
The RNLI charity saves lives at sea. Its volunteers provide a 24-hour search and rescue service around the United Kingdom and Republic of Ireland coasts. The RNLI operates over 238 lifeboat stations in the UK and Ireland and, in a normal year, more than 240 lifeguard units on beaches around the UK and Channel Islands. The RNLI is independent of Coastguard and government and depends on voluntary donations and legacies to maintain its rescue service. Since the RNLI was founded in 1824, its lifeboat crews and lifeguards have saved over 142,700 lives.
Learn more about the RNLI
For more information please visit the RNLI website or Facebook, Twitter and YouTube. News releases, videos and photos are available on the News Centre.
Contacting the RNLI - public enquiries
Members of the public may contact the RNLI on 0300 300 9990 (UK) or 1800 991802 (Ireland) or by email.


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Our five new lessons help you incorporate the Teaching Holocaust and Human Behavior unit more holistically in your classrooms.
Our five new lessons help you incorporate the Teaching Holocaust and Human Behavior unit more holistically in your classrooms.
This unit uses the 10 Questions Framework to explore two examples of youth activism: the 1963 Chicago schools boycott and the present-day movement against gun violence launched by Parkland students.
Intentionally designed for middle school classrooms, this unit explores themes of identity and community by using students' knowledge of the Memphis, Tennessee, community.
In this unit students experience how art can serve as a tool to understanding history by analyzing paintings by renowned artist and Holocaust survivor Samuel Bak.
Help students understand that their voices are integral to the story of the United States with six lesson plans that investigate individual and national identity.
Deepen students' understanding of resistance with these lessons that bring together the firsthand accounts of former Jewish partisans and historical context on the partisan movement.
Designed for students in the United Kingdom, these lessons foster the critical thinking, mutual respect, and toleration necessary to bring about a more humane society.
Use our online unit to lead students through a study of the Holocaust that asks what this history can teach us about the power and impact of choices.
Invite students to reflect on why it matters who tells our stories as they view a documentary film about the profound courage and resistance of the Oyneg Shabes in the Warsaw ghetto.
Journalists explore social media activism by discussing #IfTheyGunnedMeDown, a Twitter hashtag response to what was seen as racism and stereotypes in the images featured in the media.
How can we apply the lessons of the film Schindler's List toward standing up to hatred in our own communities? How do you engage students in conversations around racism, antisemitism and other forms of hatred? Watch this webinar to hear Mr. Spielberg discuss the legacy of Schindler's List, its impact on Holocaust education, and the importance of responding to hatred in our communities today.
This short documentary captures the spirit of Jewish life in Warsaw, Poland, before World War II.


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To find the perfect dress for Fall wedding is one of the most important part of planning a wedding.
Short wedding dress is the centerpiece of any wedding, and perhaps most importantly, to find the perfect wedding dress is a must for every bride.
Fall weddings are a rapidly advancing during the summer
And summer is still one of the most popular times for weddings, fast forward, as the fall season, fall weddings, and more and more popular, the wedding dresses of the perfect fall are even more urgent.
Fortunately, there are a lot of wedding dresses in the market, finding the perfect dress.
Perfect Wedding fashion for Fall
One of the most important things when you find the fall wedding dress is choosing what type of costume.
It is becoming increasingly popular in these large and their selection is truly amazing.
Local Seamstress
Your fall wedding dress is a personal touch, of course, other options such as a local seamstress. Many brides love the dressmaker as they can not only provide a fit custom, personalized, but also can be a big advantage too.
It is important to see fall wedding dress, for example, shop early, and then adapt a lot of work.
No matter where you buy, but it is very important to try on fall wedding dress in a store.


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Life Teen
Well I finally started Life Teen (which is a weekly bible study class at my church) finally, its the class after Edge. The first time I went to Life Teen l went to the wrong group (group 7) because they couldn't find my name on the list, l was supposed to be in group 4! The week after that I went to the right group which has a really good leader and I know a kid from chess club. There were some friends that I saw and what's cool is that I can go for the next four years until Comfirmation. So I'll probably have many friends by then.
Leave a Reply.
My name is Cameron Broyles, I'm 16 years old and I started my blog 5 years ago when I was 11. I have paraplegic cerebral palsy and cannot communicate in a traditional fashion. I am home-schooled now but I used to go to main stream public school. My love of exploring first began with going on field trips to learn about history. I play power soccer and it's become my sport of choice! I am originally from Texas but now I live in Colorado and LOVE it! I love to travel and explore but the majority of times it is much more difficult than the average person. I want this blog to not only be my mouthpiece for my friends and family but also give some ideas and maybe light a spark for other people with disabilities to get out and explore life! I was first coerced into starting a blog from my mom and dad and I have to admit that sometimes it's not my favorite thing to do but what I love most about having a blog for these past 5 years is that it's a daily reminder of all my blessings from God and how grateful and thankful I am for everything I have in my life.
October 2018


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I can't say that I don't like the 404 error page and the page with no search results... But I think it can be improved! Why not to make it in Mogr brand colors, and add the logo to it? That would lead to the term "consistency" :)
I think it would fit much better. What do you think!
Date Added: January 13, 2016
Only members can comment. Learn more.


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PřF:C7187 Experimental oncology - Course Information
C7187 Experimental oncologyFaculty of Science
Autumn 2015
- Extent and Intensity
- 2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
- Teacher(s)
- doc. Mgr. Pavel Bouchal, Ph.D. (lecturer)
doc. Mgr. Roman Hrstka, Ph.D. (lecturer)
MUDr. Petr Müller, Ph.D. (lecturer)
MUDr. Rudolf Nenutil, CSc. (lecturer)
RNDr. Bořivoj Vojtěšek, DrSc. (lecturer)
- Guaranteed by
- prof. RNDr. Zdeněk Glatz, CSc.
Department of Biochemistry - Chemistry Section - Faculty of Science
Supplier department: Department of Biochemistry - Chemistry Section - Faculty of Science
- Timetable
- Wed 17:00–18:50 A11/205
- Prerequisites
- C4182 Biochemistry II || Bi4020 Molecular biology
This course is suitable for students of master and doctoral study in biochemistry and molecular biology. The knowledge at biochemisty and molecular biology basic courses level is required.
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- there are 18 fields of study the course is directly associated with, display
- Course objectives
- At the end of the course, the students will understand the basics of biology and biochemistry of tumor cells as well as the mechanisms of malign transformation and spreading of tumors. They should be able to apply genomics and proteomics approaches and to use the main database sources in experimental oncology. The students should be able to explain the approaches used in production and purification of proteins and antibodies, principles of molecular cloning, gene therapy and the use of therapeutic antibodies. They should be able to make decisions about the proper use of biological material like model systems (cell lines), human tissues, or human plasma. The lecturers will provide insights into oncological pharmacology including drug discovery and testing, and into the basics of the use of viruses in experimental oncology. They will focus one of the lessons on the aspects of cooperation and carrier in science in general.
- Syllabus
- 1. Introduction, organization of the course (Dr. Bouchal). Physical, chemical and biological factors of carcinogenesis: Physical radiation, mechanisms of chemical carcinogens, tests of mutagenity, viral transformation. Morphological and biochemical changes in transformed cells, hypoxia. Mechanisms of cytostatic agents action, drug resistance. Examples of clinically used tumor markers.
- 2. Introduction in tumor cell biology (Dr. Hrstka). Mechanisms of malign transformation. Angiogenesis, formation of metastases. Important signal pathways in tumors. Tumor epidemiology. p53 protein, potential use in the therapy focused on the cell cycle.
- 3. Methods of molecular oncology (Dr. Hrstka). Human genome mapping, functional genomics, epigenetics. PCR based methods, chip based methods, next generation sequencing. Gene engineering. Model systems in applied research.
- 4. The use of human biological material in research (Dr. Nenutil). Human tissues as a source of information and a tool for validation of data obtained from experimental models. The use and processing of tissue samples. Predictive and prognostic pathology. Biological characteristics of tumors and their prognosis. Biological predictors of therapeutic response.
- 5. Molecular pathology and personalized medicine (Dr. Hrstka). Clinically used biomarkers, laboratory techniques, co-alteration and dysregulation of signal pathways, decision making, preanalytical issues, biomarkers in clinical studies.
- 6. Proteomics approaches in experimental oncology (Dr. Bouchal). Untargeted and targeted proteomics, protein/peptide quantification. Functional proteomics in oncology research, analysis of protein-protein interactions, biomarker discovery, verification and validation. Selection of suitable biological and tumor material and methods, design of the study, statistical analysis, data validation and interpretation. Practical examples of proteomics outputs.
- 7. Genomics and proteomics database sources in experimental oncology (Dr. Bouchal). Practical use of the algorithms: NCBI, ExPASy, UniProt, NCBI, BLAST, secondary structure and posttranslational modification prediction. Human Protein Atlas. Oncomine. Epidemiology of tumors in the Czech Republic (SVOD).
- 8. Gene therapy (Dr. Müller). Diseases curable by gene therapy. Vectors for gene therapy. Perspectives of gene therapy. Viruses and their use in experimental oncology. Characterization and categories of viruses. Tumors and viruses. Adenovirus and lentivirus vectors. Viruses and gene therapy.
- 9. Protein engineering (Dr. Müller). Protein-protein interactions, "phage display". Analysis of the activity. "Protein engineering"
- 10. Protein and expression and purification (Dr. Vojtěšek). The use of expression systems for protein expression. The use of "Tag sequences". Protein preparation for production of monoclonal antibodies. Protein preparation for functional studies.
- 11. Design, production and characterization of antibodies (Dr. Vojtěšek). Immunization schema, suitable animals and antigens. Production, purification, characterization and labeling of monoclonal and polyclonal antibodies. Application and humanization of antibodies.
- 12. Drug development (Dr. Müller). Therapeutic substance, pharmacodynamics and pharmacokinetics. The models used for "drug screening". Databases of chemical substances versus natural products. Quantitative and structural analysis of the potential therapeutic substance. Rational drug development. Clinical studies.
- Literature
- recommended literature
- REJTHAR, Aleš and Bořivoj VOJTĚŠEK. Obecná patologie nádorového růstu. 1. vyd. Praha: Grada, 2002. 206 s. ISBN 802470238X. info
- Teaching methods
- Presentations by professionals followed by class discussion and answers to students' questions. Practical use of database sources.
- Assessment methods
- Written exam followed by a short discussion with the lecturer.
- Language of instruction
- Czech
- Further Comments
- Study Materials
- Enrolment Statistics (Autumn 2015, recent)
- Permalink: https://is.muni.cz/course/sci/autumn2015/C7187


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Hi, Are there any T38s with a set of Jeckells sails? I am about to finalise my order and want to see if anyone wants to give their 2c worth. Are there any changes worth doing and areas of improvement? Did you find their 584 sq/ft chute big enough? Was it symmetrical or asymmetrical? Or did you go for a bigger headsail for light wind work? Also want to know is anyone running a jib and staysail? Even from the aft mast as per older Wharram designs? Regards Dan
COVID-19: Still dispatching orders as usual