Objective To analyze the clinical characteristics of patients with isolated clinic hypertension (ICH) compared with other hypertensive patients, and to evaluate the capacity of physicians to predict a diagnosis of ICH. Methods A cross-sectional, comparative multicenter descriptive study was made of 6176 hypertensive individuals without pharmacological treatment, subjected to ambulatory blood pressure monitoring (ABPM). In 2611 cases, ABPM was prescribed due to suspected ICH. The participants were consecutively selected in primary care centers and hospital hypertension units in all Spanish Autonomous Communities. ICH was defined by clinical blood pressure (BP) ≥ 140 mmHg (systolic) or ≥ 90 mmHg (diastolic), with diurnal ambulatory BP < 135 and < 85 mmHg (ICH1) or BP < 130 and < 80 mmHg (ICH2) or 24-h BP < 125 and < 80 mmHg (ICH3). Results ICH1, ICH2 and ICH3 criteria were met by 1807 (29.2%), 960 (15.5%) or 1133 (18.3%) subjects, respectively. Total sample mean age (SD) was 51.8 (14.1) years, and clinical BP 145.7 ± 17.3/89.3 ± 11.3 mmHg. Compared with the rest of the hypertensive individuals, the patients with ICH were predominantly female, of older age, with fewer smokers, and increased frequency of obesity. Moreover, they were more frequently nondippers, and with greater systolic BP in the office (P < 0.05), except when we used ICH3 criteria. The sensitivity and specificity of the physician predictions in relation to suspected ICH1, ICH2 and ICH3 were 48.7 and 60.4%, 52.9 and 59.7%, and 52.3 and 60.0%, respectively. Conclusions The prevalence of ICH is between 15 and 29%, depending on the defining criterion used. The 24-h ICH criteria are not affected by awake/sleep biases, and should be preferred. Clinical capacity for predicting ICH is low.


The incidence of the pulmonary complications in patients with acute pancreatitis is up to 60%, from mild hypoxaemia without clinical or radiological abnormalities to severe acute lung injury. Although a number of reviews has described clinical evidence of pancreatitis-associated lung injury (PALI), there is still a lack of information on potential interorgan signalling involved in the development of PALI. The present review discusses the potential factors that have been considered as candidates responsible for interorgan signalling coupling pancreatitis to lung injury. Inflammatory mediators produced from the pancreas, leucocyte system and extrapancreatic organs may directly or indirectly contribute to the high concentration in the circulation, activate circulating leucocytes, initiate the inflammatory responses of pulmonary resident cells or induce acute lung injury. Circulating leucocytes have been suggested to play an important role in interorgan signalling during the development of PALI, by producing ...


Service integration in Cloud computing reusing existing services nowadays presents a very important research problem. It is presented during different software's and application implementations and the idea comes for something new, innovative, and contemporary, enabling several services to be integrated and by providing stable, decentralized and just in time services. In SEE University there are different web application platforms that serve to offer services to the students but not integrated, they are isolated in psychical and business process aspects. The aim of this paper is to propose a modeling platform (framework) in SEEU, which is tailored to build efficient, elastic and autonomous applications from tasks and services provided by the Cloud environment, and to define patterns that can result in the efficient optimization of money and resources.


`Heather' is commonly used to qualify honeys issuing from the Ericaceae family. As mellissopalynology and sensory assessments alone were not sucient to authenticate their  ̄oral origin, volatile compounds from Erica arborea and Calluna vulgaris uni ̄oral honeys were investigated. Flavours were isolated via dichloromethane solubilisation, followed by a Likens-Nickerson simultaneous steam-distillation/solvent extraction. The extracts exhibited an intense honey aroma, representative of their  ̄oral origin. Four hundred compounds were separated by gas chromatography and mass spectrometry. Among them, and in comparison with 11 other honey types, 4 proved to be markers of the Ericaceae family. Moreover, 3 were speci®c for Calluna vulgaris species and 3 others discriminant for the Erica arborea samples. # 1998 Elsevier Science Ltd. All rights reserved..


This report presents analytical and experimental studies that describe the performance of nuclear waste packages at the system level. Several water chemistry modules were developed, and ground-water-radiolysis studies were performed to examine the production of radiolytic species at the outside surface of waste packages. Uncertainty analysis studies with a UO/sub 2/ water chemistry model assessed the importance of input parameters on the variability of calculated solubilities. A shell for a computer code was developed that provides an alternative method for examining the system performance of high-level waste packages. Integral experiments were conducted to examine interactions between components of the waste package and repository, bringing together elements of repository environments with components of spent-fuel waste forms. The system performance investigations showed that radiolysis effects are not significant when the gamma source is shielded by the overpack. The production of oxalate is related to bicarbonate concentration and dose rate. The dissolution of UO/sub 2/ may be influenced significantly by solution pe and chloride concentration. Spent fuel performance studies showed that spent fuel rod sections with microscopic failure openings showed unexpected high release rates for some radionuclides when compared with releases from macroscopic failure openings. 121 refs., 81 figs., 30 tabs.


The paper reveals one of the key problems of the modern artistic pedagogy, which lies in the application of the potential of creative fantasy and imagination of students in the pedagogical process. It considers the various preconditions for the development of the ability to fantasize, depending on the individual capabilities of students. Reliance on initially individual systems of perception of artistic information with the subsequent development of this perception to the level of creation of full-fledged artistic images and interpretations is proposed as a leading pedagogical strategy. The interrelation between the organized social and aesthetic experience of students and possibilities of creative fantasy and imagination is established. In this process, the role of educational creative teams as a space of social, artistic and aesthetic development of students is highlighted.


This paper study the dielectric and mechanical properties of poly (methyl methacrylate)-nickel silica core-shell nanocomposite. Ni@SiO2/PMMA nanocomposite films were prepared by incorporating Ni@SiO2 nanoparticles in PMMA matrix using the solution casting method. The morphology of the prepared nanoparticles was examined through a High-resolution transition electron microscope (HRTEM), which revealed the formation of SiO2 shell at Ni magnetic nanoparticles. The dielectric properties of the nanocomposite films were studied as a function of temperature and frequency in the ranges of 30–180°C and 100 Hz – 5 MHz respectively. The incorporation of the nano Ni@SiO2 to PMMA has a positive effect on the dielectric constant ε′ of the nanocomposites, as well as, ε′ improved with increasing temperature. The real electric modulus (M′) of composites confirms the occurrence of dispersion in all composites at all temperatures. While dielectric loss tangent ε ″ and the loss part of electric modulus spectra (M) exhibit relaxation peaks which characterize possible relaxation of interfacial polarization in the interface between Ni@SiO2 core-shell and PMMA matrix, these peaks have shifted towards higher frequency with temperature. The relaxation and activation energies, Ec and Ea values decreased from 0.49 to 0.40 eV and from 0.87 to 0.70 eV respectively as Ni@SiO2 content increased. The ac conductivity of the nanocomposite films has deeply increased with increasing temperature and Ni@SiO2 content. The longitudinal modulus (L), shear modulus (G), Young's modulus (E), and bulk modulus (B) of films were studied and they increased as the filler increased from 0 to 15 wt.%.


Quantitative and Qualitative exploration of clinical and diagnostic data using advanced analytics could unravel hidden medical knowledge by finding correlations, causations, and associations between apparently independent variables. Therefore, the scope and use and of Data Mining techniques in the current healthcare system is increasing steadily. In regard to this, we will discuss the disciplines, methods, models, algorithms, and results, and how these techniques would help in performing studies including but not limited to long-term prospective and retrospective studies, population studies, correlation studies, multicentric, multiracial, phased studies, meta-analysis, pharmacovigilance, etc. on Ayurvedic drugs and methods. We have discussed the applications of Data Mining on healthcare that is being implemented in developed countries. We have also discussed the issues like lack of quality data and record-keeping, and other issues and challenges in conducting ayurvedic studies in India, and how the National Digital Health Blueprint would be a game-changer in the current healthcare system of India.


An approach is proposed to study the relationship between water, food and energy resources, supply chains, social and medico-epidemiological spheres based on the multi-sectoral Lorenz model. The model combines in a one framework similarly described sectors of the economy, each of which is considered in terms of the level of productivity, the number of jobs and the level of structural disruptions. As a result of modeling the conditions of occurrence of deterministic chaos has been defined, and trajectories of change of social and economic factors which allow to reduce number of structural disturbances has been calculated. This is achieved by changing the ratio of supply and demand for jobs and products. Numerical study of the model has been allowed us to analyze how changes in the balance of supply and demand in interconnected systems lead to a chaotic stable attractor. It has been considered how the sequential transition of interconnected sectors to the mode of deterministic chaos is reflected in the integrated mode of operation when there is a kind of phase synchronization of self-oscillations of six connected generators.


Frequent pattern mining has been playing an essential role in knowledge discovery and data mining tasks that try to find usable patterns from databases. Efficiency is especially crucial for an algorithm in order to find frequent itemsets from a large database. Numerous methods have been proposed to solve this problem, such as Apriori and FP-growth. These are regarded as fundamental frequent pattern mining methods. In addition, parallel computing architectures, such as an on-cloud platform, a grid system, multi-core and GPU platform, have been popular in data mining. However, most of the algorithms have been proposed without considering the prevalent multi-core architectures. In this study, multi-core architectures were used as well as two high efficiency load balancing parallel data mining methods based on the Apriori algorithm. The main goal of the proposed algorithms was to reduce the massive number of duplicate candidates generated using previous methods. This goal was achieved for, in this detailed experimental study the algorithms performed better than the previous methods. The experimental results demonstrated that the proposed algorithms had dramatically reduced computation time when using more threads. Moreover, the observations showed that the workload was equally balanced among the computing units.


A subsurface radar using a multi-frequency signal has been developed. It is designated for surveying building structures and works. The characteristic feature of this device is the possibility of obtaining sounding plane radio images featuring a high resolution attaining 1...2 cm. The main applications of this device includes the survey of building structures to reveal their heterogeneities and defects and the investigation of premises to detect bugging devices.


By analyzing the main problems and teaching situation of higher vocational ASP.NET Dynamic Web Design course,based on the combination of ASP.NET Dynamic Web Design characteristics of the course,the essay gives vocational ASP.NET Dynamic Web design course overall objectives,and then closely the teaching objectives of the course,the essay discusses this course content design concept and content modules.


Population of the world's largest database of stress intensity factor (K) solutions began in 2002 with the calculation of 5.6 million K solutions for diametrically opposed unsymmetric corner cracks at a straight shank hole in a finite width sheet subject to remote tension, remote bending, and bearing loading. For the last 20 years, the well-known Newman/Raju K solutions have been used for predicting fatigue life for the case of two cracks of the same shape and size. Differences between the Newman/Raju solutions and new K's exist and the effect on inspection intervals and fatigue lives is assessed. In addition, the accuracy of engineering assumptions required to use the Newman/Raju solutions are evaluated. Overall, the correlation between the two solution sets was quite poor.


We compared the course and outcome of schizophrenia in two groups: (i) hospitalised patients (HP) (n = 5980) who were identified based on their first hospital admission for schizophrenia and (ii) outpatient‐treated patients (OTP) who received disability pension because of schizophrenia but who had no hospital admissions for schizophrenia or other psychotic disorder before having been granted a disability pension for schizophrenia (n = 1220). Outcomes were compared using data on mortality, psychiatric hospital utilisation, relapse rate and occupational functioning.


Computational Electromagnetic (CEM) techniques have become an indispensable tool in efficient EM modeling, analysis and design process. EM subsurface scattering is a broad field of research with varying degree of complexity. Due level of the obscurity involved in the subsurface scattering investigation, it is therefore considered imperative to explore this problem area of EM for better insight through CEM-based study and models. In this paper, frequency domain CEM techniques are studied which have been tested to provide solution for subsurface scattering problems in terrestrial environments. The development of CEM methods for comparatively more complex problems of scattering from embedded non-metallic inhomogeneity in lossy, rough and layered media remains the focus of this article. The objective here is to provide an overview of CEM development by selecting few examples from the wide area of subsurface EM scattering.


We propose a third-order-accurate variable-mesh two-parameter alternating group explicit (TAGE) iteration method for the numerical solution of the two-point singular boundary value problem subject to boundary conditions u(0)=A, u(1)=B, where A and B are finite constants. We also discuss a Newton–TAGE iteration method for the third-order numerical solution of a two-point non-linear boundary value problem. The proposed method is applicable to singular and non-singular problems and is suitable for use on parallel computers. The convergence analysis is briefly discussed. Computational results are provided to illustrate the proposed TAGE iterative methods.


Substance use is a societal and an important public health concern in this 21st century. The number of substance use cases and relapse are increasing geenrally, thus slowing down the progress made in the care and treatment of individuals with substance abuse disorders. The study identified determinant of relapse among the rehabilitated substance use patients in Neuropsychiatric hospital, Aro, Abeokuta. The study adopted cross-sectional, selected 125 relapse substance use patients and their primary informal caregiver on the wards and clinics at neuropsychiatric hospital, Aro, Abeokuta. An interviewer-administered structured questionnaire was used to obtain data on determinants of relapse among the rehabilitated substance use patients and the retrieved data was analysed using SPSS version 21 for descriptive statistics. The findings shows that nearly half (44.4%) of the respondents were below 20 years, majority (64.5%) were male, 40.3% married. Most (69.4%) of the respondents agreed that the patient have friends who use drugs, 71.0% of the patients were currently relapsed, though majority (72.5%) of the patients were on treatment either outside or/and in-ward under control compliance. Conclusively, higher proportion were currently relapsed and had varied factors correlating the relapse; male, under 20years. Hence the client needs be proactively managed to prevent relapse through prompt therapy / care of psychotic patients lengthy to lead a high quality of life.


In this section, a modified finite-time controller will be designed for the inner attitude control loop of a coaxial rotor. The convergence term in the MFTC is used to track to reference trajectories with finite time convergence. This convergence term include two kind of the correction mode. The nonlinear term is great when the system trajectories is far away from the desired trajectories, while the linear correction term is great when the system trajectories is around the reference trajectories.


When a clinical MR scan is acquired, there might be missing tissue contrasts due to the corruption by patient's motion during long scan time. In this study, we propose a method to synthesize the missing T2-weighted or FLAIR contrasts from a T1-weighted image using physics-constrained neural network. We incorporate the Bloch equations that generate MR contrast images from tissue parameter maps based on MR physical models into a synthesis neural network and show the improved performance compared with the existing U-Net directly synthesizing from a T1-weighted image.


The study of hyperuniform states of matter is an emerging multidisciplinary field, influencing and link-ing developments across the physical sciences, math-ematics, and biology (1, 2). A hyperuniform many-particle system in d -dimensional Euclidean space is characterized by an anomalous suppression of large-scale density fluctuations relative to those in typical disordered systems, such as liquids and amorphous solids. As such, the hyperuniformity concept the traditional notion of long-range to only all perfect crystals and quasicrystals but also exotic disordered states of matter. algae robustly self-organize into disordered hyperuniform states through long-range hydrodynamic interactions at air – liquid interfaces. How is hyperuniformity quantified? Such systems astructure ð scattering wave-number j


Brief survey of the activity being carried out in IPPE in the field of calculation and experimental studies on MA transmutation is given. Results of recent developments on calculation code and crosssections supply for MA transmutation works are presented. Calculation investigations on incineration of Am and Cm with shares of rare-earth elements in BOR-60 reactor are described for the forthcoming experiment. Comparative analysis on MA transmutation in fast and thermal reactors is given.


Minimally invasive total knee arthroplasty is growing in popularity. It appears to reduce blood loss, reduce hospital stay, improve post-operative quadriceps function and shortens post-operative recovery. We show our experience of minimally invasive TKA with a computer navigation system. Forty patients who underwent MICATKA were compared with forty patients having conventional CATKA. Component positioning was assessed radiographically with AP long leg standing views. Knee Society Scores, length of stay and recovery of straight leg raise was also recorded pre-operatively and at 6, 12, 18 and 24 months. Pre-operative Knee Society Scores showed no significant difference between the two groups. Post operatively the mean femoral component alignment was 89.7 degrees for MICATKA and 90.2 for CATKA. The mean tibial component alignment was 89.7 degrees for both. Knees society scores at 6, 12, 18 and 24 months were statistically better in the MICATKA (p MICATKA is a safe procedure with reproducible results. Alignment is equivalent to CATKA. It gives statistically significant improvement in Knee Society Scores compared to the open procedure. The length of stay and time to straight leg raise is also reduced. At a minimum of 2 years follow-up we have seen no revisions and no evidence of radiographic loosening. A randomised multi centre trial is under way and early results are awaited.


ABSTRACT THE three-stage turkey production system utilizes a two-story building. Day old poults are started in the brooding section (first stage) utilizing one-third of the se-cond floor area. At about 5 wk of age the birds are moved into the growing section (second stage) utilizing the other two-thirds of the second floor. After about 5 to 6 wk in the growing section the birds are then dropped to the finishing section (third stage) utilizing the entire first floor area where they are finished out to desired market weight usually from 5.87 to 7.26 kg (13 to 16 lb). The three-stage system increases annual production by about 30 percent compared to conventional all-in all-out systems, provides more efficient use of building space and equipment, and reduces energy costs for brooding.


The tension of strings on a badminton racket can be adjusted by players according to their personal experiences. The best way to execute such an adjustment remains unclear. A finite element model was employed in this study to investigate the effect of having nonuniform string tension on string-bed deformation, and the direction of force applied to shuttlecock head upon impact. The racket model was based on a commercially available racket with a simplified string-bed of 16 strings established using SolidWorks. A displacement was applied to the ball to simulate impacting on the string-bed. The simulations revealed that slightly lowering the tension of off-centered strings had a minimal effect on the von Mises stress distribution of the ball and string-bed. The off-centered impact caused comparable contact force magnitude but altered force direction. Further investigation is needed for understanding the effect of varying string tension on badminton racket performance.


11529 Background: Nab-paclitaxel (albumin-bound paclitaxel) has shown preclinical activity against pediatric solid tumors. Preclinical data in EwS PDX models suggested high activity of nab-paclitaxel in tumors expressing high-levels of SPARC. Tumoral SPARC facilitates the accumulation of albumin in the tumor and increases the effectiveness of albumin-bound paclitaxel. Nab-paclitaxel utilizes albumin to deliver paclitaxel via caveolin-mediated endocytosis which is expressed in the EwS cells surface. We hypothesized that SPARC can be a predictive biomarker for nab-paclitaxel in EwS and DSRCT that could potentially be relevant for a better design of clinical trials and personalized treatments using nab-paclitaxel. Methods: Main endpoint of GEIS-39 was the overall response rate (ORR) assessed by RECIST 1.1 criteria with centralized pathology and imaging review. Secondary objectives included safety according to the CTCAE 4.0 criteria. Patients aged ≥ 6 months and ≤ 40 years, with relapsed/refractory DSRCT were eligible after having received at least one previous poly-chemotherapy line; EwS must have received at least two standard chemotherapy lines. Prior taxane therapy was accepted. Central pathology review selected for tumors with > Grade 3 (intense and diffuse) expression of SPARC by immunohistochemistry to be eligible. Nab-paclitaxel was administered as follows: age ≥ 21 and ≤ 40 years: 125 mg/m2 days 1, 8 and 15 in cycles of 28 days; age ≥ 6 months and ≤ 20 years: 240 mg/m2 days 1, 8 and 15 in cycles of 28 days. A 30% ORR was anticipated with a sample size of 25 patients needed to test the hypothesis. Stopping rule was set at 1 response within the first 16 treated pts. If 5 or more successes were observed in 25 pts, the results of the trial will warrant further investigation. Results: Twenty-nine patients were enrolled from June 2017 until October 2019, 11 DSRCT and 18 EwS. Median age was 32 years (range 14-69), and 5 females and 24 males were included, having received a median of 3 previous systemic treatment lines. Patients received a median of 3 cycles of nab-paclitaxel (range 1-17). In the EwS cohort an ORR of 33.3% (all partial responses, median duration 2 months) and 16.7% of stabilizations were achieved. No objective responses were observed among DSRCT pts, but 27.3% of pts achieved a stabilization. Overall, median progression free survival was 2.8 months and median overall survival 12.1 months, with no significant differences between DSRCT and EwS cohorts. Most common grade 3 toxicities were neutropenia (20.7%) and diarrhea (10.3%). Conclusions: Single agent nab-paclitaxel in biomarker selected EwS patients, but not in DSRCT, provided clinically meaningful activity that deserves further development. Nab-paclitaxel had a manageable adverse event profile. Clinical trial information: 2016-002464-14.


The openness of Polish space to the new challenges of civilisation causes that the historically shaped spatial structures are currently undergoing dynamic changes. These changes result both from the contemporary world-wide trends, primarily globalisation, metropolisation, development of the information civilisation, as well as the widespread introduction of the principles of free market, development of car transport, changes in the lifestyles, and the process of European integration. All these processes exert an essential influence, both on the socio-economic activation and on environmental protection. Among the metropolitan areas developing in Poland the most important spatial changes are taking place within the Metropolitan Area of Warsaw (Furman, 2001). The reach of this area is estimated at some 30–40 km from the centre (Chmielewski, 1996). It is the sole Polish metropolis that is perceived in Europe, ranked at the end of the third ten of the European metropolises (Jałowiecki, 2000). During the recent years the rate of landscape degradation within the Metropolitan Area of Warsaw significantly increased. It can be supposed that the contemporary spatial processes will lead to the lowering of life quality. The currently observed manner of managing space might be called "unsustainable" within many areas. This fact is reflected, in particular, through (Degórska, 2002):


The prognosis of patients with brain metastases from breast cancer is poor. Median survival after radiotherapy is 5-6 months. We report a patient in whom a complete response of a brain metastasis was induced by megestrol acetate at a daily dose of 160 mg orally.


Received: 09, Feb, 2015 Final Accepted: 13, March, 2015 Published Online: 18, March, 2015 Evaluating indicators such as productivity and efficiency, make managers aware at various levels of the strengths and weaknesses of the organization. In today's business environment, organizations try to improve their efficiency in order to have more power in the global competition. The present paper presents an integrated fuzzy approach for the efficiency evaluation of industrial co-operatives. This method consists of three different techniques: (1) identify important evaluation criteria based on Balanced Scorecard(BSC) According to the previous literature review and expert preference ; (2) apply fuzzy inference system(FIS) to eliminate unsuitable criterion; and, (3) develop data envelopment analysis (DEA) approach for the final evaluation. Among the indicators "The capacity of machines and production to capacity ratio" determined as the input parameters and "annual profits, customer satisfaction and continuous improvement of productivity" were considered as the output of the proposed DEA model. Finally, an actual industrial application is presented to demonstrate the proposed method. By transforming the linguistic variables to quantitative numbers by fuzzy numbers, the DEA model was formed and four units of the fifteen cooperatives were identified as efficient units..


We study pairing symmetry of noncentrosymmetric superconductors based on the extended Hubbard model on the square lattice near half-filling, using the random phase approximation. We show that $d+f$-wave pairing is favored and the triplet $f$-wave state is enhanced by Rashba-type spin-orbit coupling originating from the broken inversion symmetry. The enhanced triplet superconductivity stems from the increase of the effective interaction for the triplet pairing and the reduction of the spin susceptibility caused by the Rashba-type spin-orbit coupling which lead to the increase of the triplet component and the destruction of the singlet one, respectively.


There is often a need to map a multi-dimensional space on to a one-dimensional space. For example, this kind of mapping has been proposed to permit the use of one-dimensional indexing techniques to a multi-dimensional index space such as in a spatial database. This kind of mapping is also of value in assigning physical storage, such as assigning buckets to records that have been indexed on multiple attributes, to minimize the disk access effort.
In this paper, we discuss what the desired properties of such a mapping are, and evaluate, through analysis and simulation, several mappings that have been proposed in the past. We present a mapping based on Hilbert's space-filling curve, which out-performs previously proposed mappings on average over a variety of different operating conditions.


Non-linear resonance of quantum beats under harmonically modulated excitation in a magnetic field is considered as a method of determining the Landt factor for a single electronic-vibrational-rotational (EVR) level of a diatomic molecule in its electronic ground state. The role of the sign of the Land4 factor in the ground and excited levels, stimulated emission and "fly-through" relaxation conditions are analysed using a semiclassical description of the beat resonance signal in laser-induced fluorescence. Refined Land& factor values of EVR levels of "I&(X 'X: ) and ?'es(XO: ) are obtained by means of fitting experimental signals. As a rule, the orbital and spin angular momenta of diatomic molecules in the ground state have zero-value projection on the molecular axis. In this case magnetism may be due to nuclear rotation, as well as to nonadiabatic term interaction (the "electronic" contribution). In this connection experimental data on LandC g factors of separate rovibronic levels are of considerable interest. g factor measurements of such states are based on the optical pumping effect [ 11 (in the sense of orientation or alignment) of the lower EVR level in the process of its depopulation, e.g. in the process of optical absorption. During absorption, coherence between magnetic sublevels of the ground state is created, which is transferred by the same light field to the excited state and manifests itself through subsequent fluorescence. Coherence may be destroyed by an external magnetic field causing a splitting of the degeneracy of magnetic sublevels (ground-state level crossing effect [ 2 ] ), but may also be restored in case of modulated pumping [ 3 1, producing quantum beats after pulsed excitation and beat resonance (BR) at harmonically modulated excitation. The BR method can be easily effected at laser excitation, see for example ref. [4] for neon. The methods have first been applied to ground-state molecules in refs. [2,5,6] for Tel and Kz_ Correct description of the shape of the registered non-linear signal is required for precise determination of the splitting frequency, accounting for resonance peak shifts in the presence of the pumping light field. From this point of view the approximation applied in ref. [ 51 and giving an analytical description in terms of polarization moments is not sufficiently precise. This fault is removed in refs. [ 7,8] by an approach based on classical description of angular momentum orientation. The present paper forms a further stage in this approach. It takes into account effect of stimulated radiation, fly-through effects, and also analyses the role of Land6 factor sign of states interconnected by laser radiation. This has made it possible to obtain refined LandC factor values of rovibronic levels of 39K2( X '2: ) and i3@Tez(X0,+ ).


To the Editor: Clozapine is used in patients with treatment-resistant schizophrenia.1–3 Agranulocytosis, myocarditis, and cardiomyopathy are potentially fatal side effects of clozapine, although the incidence is low.4 Tachycardia occurs in approximately 25% of patients, with a mean increase of 10 to 15 bpm,5 and appears to be related to vagal inhibition by the anticholinergic properties of clozapine.6 Here, a case of dose-dependent supraventricular tachycardia in a schizophrenic patient taking clozapine is presented.


In this paper we assess appropriate statistical methodology for modelling a continuous response variable with data recorded through a longitudinal social survey. The variables of interest in this study have been captured by the Longitudinal Suvery of Immigrants to Australia (LSIA) which is the most comprehensive suvery of immigrants ever to be undertaken in Australia. The LSIA cohort had a sample siza of 5192 Principal Applicants (PA) and was completed in February 1999. The survey consisted of three waves of interviews for each participating immigrant, at fixed time intervals following arrival in Australia. The purpose of the model is to quantify the relationships between income levels of immigrants and various explanatory variables collected throughout the survey. Of particular interest is the trend in the relationship between an immigrant's Visa Category and income level as the settlement process continues. Results show that predicted mean income is highest for employed PAs and income for males is higher than income for females. For employed PAs, the predicted mean income is highest for the Independent Visa Category but for non-participant and unemployed PAs, income is highest for those with a Humanitarian Visa Category. It appears that once an immigrant enters the labour force, the level of income achieved is not associated with Visa Category.


In this article the semantic evolution of the modal verb -sobol- in Luganda is examined through the analysis of a diachronic corpus spanning the last 120 years. It is shown that the usage frequency of this verb increased exponentially between the early 20th century and the present, and that its use as a lexical verb has dramatically decreased during the same time span. The corpus data furthermore substantiate that its modal uses have been extended from the exclusive expression of dynamic possibility until the 1960s to deontic possibility. Methodologically, this is the first full-scale article within the young field of Bantu corpus linguistics in which a corpus-driven study is performed on a diachronic corpus. The approach is not only shown to be feasible, but the encouraging results will hopefully entice colleagues working on the Bantu languages to undertake the building and analysis of such diachronic corpora for linguistic purposes.


We investigate the stability of aqueous barium titanate suspensions as a function of dispersant architecture, ionic strength, counterion valency, and particle size. Both pure polyelectrolytes, poly(acrylic acid) and poly(methacrylic acid) (PMAA), and comb polymer dispersants composed of a PMAA backbone with methoxy-poly(ethylene oxide) (mPEO) teeth of varying molecular weights are studied. While each dispersant imparts stability to barium titanate suspensions at low ionic strength (<∼0.01M), only the PMAA–mPEO comb polymer with the longest teeth provides stability at higher ionic strengths independent of particle size and counterion valency. Our findings provide new insight into the design of comb polymer dispersants for stabilizing aqueous ceramic suspensions over a broad range of processing conditions.


The gyrokinetic Particle-in-Cell (PIC) method is a critical computational tool enabling petascale fusion simulation re- search. In this work, we present novel multi- and manycore-centric optimizations to enhance performance of GTC, a PIC-based production code for studying plasma microturbulence in tokamak devices. Our optimizations encompass all six GTC sub-routines and include multi-level particle and grid decompositions designed to improve multi-node parallel scaling, particle binning for improved load balance, GPU acceleration of key subroutines, and memory-centric optimizations to improve single-node scaling and reduce memory utilization. The new hybrid MPI-OpenMP and MPI-OpenMP-CUDA GTC versions achieve up to a 2× speedup over the production Fortran code on four parallel systems - clusters based on the AMD Magny-Cours, Intel Nehalem-EP, IBM BlueGene/P, and NVIDIA Fermi architectures. Finally, strong scaling experiments provide insight into parallel scalability, memory utilization, and programmability trade-offs for large-scale gyrokinetic PIC simulations, while attaining a 1.6× speedup on 49,152 XE6 cores.


Potato (Solanum tuberosum L.) ranks fourth on the list of the most important food stable worldwide. It cultivates in Egypt in three cycles, of which is the summer cycle where the predominant high temperature stress which exert an adverse effect on the growth of the whole plant. Therefore, this study hypothesized that foliar application of cytokinin-phenylureaderivative as (CPPU) and salicylic acid (SA) could be a crucial role in this context. Thus, two open field experiments were conducted during summer seasons of 2016 and 2017, in a private farm of sandy loam soil, at Abou Elmatamer city, Behiera Governorate, Egypt. Certified imported potato seeds of 'Cara' cv. were used after splitting-up. Cut seedy explants (ca. 40 g) contain one eye each were planted at 0.80 m wide and 0.17 m apart between hills, using four concentrations of the synthetic cytokinin CPPU (0.00, 0.04, 0.08, and 0.12 mM) and five concentrations of SA (0.00, 1.00, 2.00, 3.00, and 4.00 mM) were foliar applied separately and in combinations. Control plants were sprayed with distilled water. The effects of both variables and their combinations were investigated on the vegetative growth-related characters, yield and its components, tuber quality, leaves and tubers chemical composition. The obtained results declare, in general, that foliar application treatments of cytokinin as CPPU and salicylic acid (SA) alone or in combination to potato plants gave, significantly, the highest average values of both yield and quality compare to untreated plants. The combination between 0.12 mM CPPU plus 4.00 mM SA might be considered as an optimal treatment for the production of high yield and good quality of potato plants under the environmental conditions of Behiera Governorate and other similar regions.


Aiming at seismic prospecting signals,the comparisons of some effective time-frequency analysis methods for nonstationary signal are studied,including short time Fourier transform(STFT),wavelet transform(WT),S transform(ST),Wigner distribution(WVD),smoothed pseudo-Wigner distribution(SPWVD),cone-kernel time-frequency distribution(CKD) and adaptive optimum kernel time-frequency representation(AOK).Numerical methods and applications are implementd on base of their principles.Firstly,time-frequency representations of the above methods and testing computations are implemented with a modeling unstable seismic signal and time-frequency attributes are extracted.The comparisons of the results of above methods are studied according to the time-frequency localization precision and cross-terms suppressing.Secondly,the above methods are applied to real 2D seismic data and seismic attributes extraction for instantaneous frequency and instantaneous bandwidth.On base of the results,it can be concluded that AOK time-frequency representation is the best method among the above methods according to the time-frequency localization precision,cross-terms suppressing,sequences detection validity and worthing to do more research for seismic attributes extraction and spectral decomposition.


This article analyzes shares and rankings of Russian bioscience publications and journals in international bibliometric databases. Studying scholarly output, international collaboration, and the share of Russian papers both in national and international journals enables the authors to highlight the current state of biological science and journals in Russia and outline some pronounced trends. A comparative analysis with the leading countries confirms good representation of Russian bioscience journals among other international serials. Certain problems remain unsolved, however: low impact factors, overrepresentation of national papers, and poor online services. Thus, Russian publishers should correct their editorial policy to improve availability and performance of serials.


The application of elastic guided waves to inspect structures has a long history, and is quite common for online monitoring of structures nowadays. In thin-walled structures, special elastic guided waves, named after Horace Lamb who described these waves first in 1917 [1], occur. Those plate-like structures have free, parallel surfaces and are stress free at the top and bottom boundaries. Lamb wave based monitoring systems have several advantages compared to other non-destructive evaluation methods, for example long range inspection capabilities, sensitivity to structural damages, etc. To use them efficiently, one important point is to understand coupling effects between the actuator and the structure which affect the induced wave front. Ha [2] performed studies to understand the influence of ambient temperature, height and Young's modulus of the bonding layer on the emitted signal. The impact of soldering points at the top of a piezoelectric actuator has been shown by Willberg et al [3]. The presented paper is focused on the variation of the glue layer angle between the actuator patch and the plate. This kind of variation is a typical effect caused by fixing the actuator to a plate as experimental investigations at manufactured plates have proven. If the excitation source (e.g. circular patches)


Abstract : In 1989, no Eighth U.S. Army installations had yet acquired a complete library of Republic of Korea (ROK) hazardous waste regulations. Since the Korean Waste Management Law is the primary las governing the U.S. Forces Korea (USFK) hazardous waste management program, the USFK/EUSA Environmental Program Office (EPO) tasked the U.S. Army Construction Engineering Research Laboratory to translate the Korean Waste Management Law and attendant documents into English. This special report contains English translations of: (1) the Korean Waste Management Law, (2) the Korean Ministry of Health and Safety Administration (MOHSA) Order To Implement the Waste Management Law, (3) the Korean Presidential Decree To Implement the Waste Management Law, and (4) Korean government forms for documentation of waste disposal in that country. These translations will help USFK installation planners in Korea to formulate a hazardous waste management program that recognizes and adheres to host country regulations.


This paper presents a general and nimble optical handwritten numerals recognition system which uses G 3 fascimile transceiver as the input device.By connecting a C 3 fascimile with a special designed board and with a central computer. the system can complets the recognition program very well and it also can locate the recognition program in RAM and/or ROM. Flexible recognition algorithms can perform raster scanning of the Huffman code produce by the fax only once. The hanger-chain algorithms can seperate handwritten numerals and obtain the first features at the same time. T h e speciality is flexible . f a s t-n o demand for big memory. The flexible recognition algorithms can read statistical charts of various sizes and formats written by different writers. #.The structure of system Based on the market investigations both at home and abroad .more and more government departments at different levels and various enterprises have now used computers widely to collect and process data and there is a great demand for better character recognition system.According to the experience of using past special and dull OCR readers. we have worked out a simple and practical open OCR system which can renew itself according to rapid development of hardware devices. (see fig. 1.) With the rapride development of the IS1 technology . the hardwarw price of OCR machine can be deduced by using advance CPU and advance system struct. And this can made the recognition system more easy to be use. more presise. more flexible and opening. Eespecialy by inserting a special board into the computer to consist the recognition system. As the properities to price of fax keep growing , we just use Japanesefax Panasonic UP-gl5 as the input file scanner. As there isn't any changes in the hardware of the fax, the system can be connected with any developing G3/G4 fax with R S-232 interface which is used as synchroinism data communication by means of the HDLC recommandation and the SIO chip. T h e communication recommandation is written by the CCITT T.30 standers. and it is located in the ROM of the special board designed communication M H code discrete grid)


Polyamide-containing fibre materials are given an anti-stain finish by treating them with a sulpho-containing aromatic formaldehyde condensation product in combination with polyacrylic acid, the treatment with the two components being carried out in any desired order or simultaneously.


The anion in the structure of the title compound, C7H7N2+·H+·2C9H7O5−, has a CO2H unit on the aromatic ring. Two anions are linked through an `acid H' atom (which lies on a center of inversion) to give a monoanionic entity. Adjacent entities are linked into a linear chain through hydrogen bonding involving the CO2H units. The chains are connected into a layer structure through the benzimidazolium cations, which possess C2 symmetry.


Social question and answer (social Q&A) sites facilitate people to share and distribute knowledge, expertise and experience every day. Key phrase extraction plays a fundamental role for content indexing. In this paper, a key phrase extraction algorithm for social Q&A sites is proposed which make the most of the structure and characteristics of the sites. Some Q&A related features are considered in the algorithm. The algorithm is trained with data of three social Q&A sites using logistic regression model. Experiments show that the result is better than the baseline system.


This paper presents large eddy simulation (LES) turbulent combustion models for premixed methane/hydrogen/air mixtures which account for stretch, heat loss and Lewis number effects by means of a previously proposed turbulent flame speed expression [1]. In this expression stretch and heat loss effects are introduced by means of strained non-adiabatic laminar consumption speed calculations in fresh-to-burnt counter flow configurations with detailed chemistry, and preferential diffusion of hydrogen is accounted for by calculating an effective Lewis number of the reactants.
 To validate and analyze the performance of the models, large eddy simulations of fully premixed atmospheric bluff body stabilized methane/hydrogen/air flames are compared against experimental measurements [2, 3]. Heat release distributions and mean flame shapes are compared against OH* chemiluminescence data. Flame dynamics are investigated by extracting flame transfer functions (FTFs) with system identification (SI) methods and comparing them with measured FTFs from experiments.


The invention relates to a power unit testing circuit for an IGCT (integrated gate commutated thyristor) three-level medium voltage frequency converter. The frequency converter is technically characterized in that an input switch Q1 is connected with a voltage regulator T1 and then is respectively connected with a transformer T11 and a transformer T12 by virtue of a branch switch Q11 and a branch switch Q12, the transformer T11 and the transformer T12 are respectively connected with a rectifier A and a rectifier B, the rectifier A and the rectifier B are respectively connected with a filter capacitor CA and a filter capacitor CB in parallel, a discharge circuit is respectively connected with the two ends of the filter capacitor CA and the filter capacitor CB in parallel, the discharge circuits are connected with a grounded circuit, the two filter capacitors are connected with a tested power unit by virtue of a di/dt buffer circuit, the tested power unit is connected with a test load, and a controller for test is connected with the discharge circuits and the tested power unit. By adopting the power unit testing circuit provided by the invention, a temperature rise test of the tested power unit and an on-off test of a single-IGCT device and a bridge arm are realized, and the power unit testing circuit provided by the invention has the characteristics of simple test circuit, low total capacity, low energy consumption, no pollution to a power grid, convenience in operation and the like.


Abstract Yellow nutsedge (Cyperus esculentus) is a difficult weed to control in conifer nurseries. Soil fumigation with methyl bromide has been used to control yellow nutsedge for years but may not...


Axisymmetric jets issuing from pipe, nozzle and orifice were observed to investigate the effect of exit geometries on downstream behavior, using the hydrogen bubble method for flow visualization. It is found that the disturbance mode on the jet column depends on boundary layer thickness, δ, at the exit. A thin boundary layer produces varicose (axisymmetric) disturbances, while a thick boundary layer produce helical (non-axisymmetric) ones. The critical value of δ, which distinguishes one mode from the other, is determined as about 0.21 times the exit diameter. In the case of the varicose mode, position and frequency of vortex ring formation, transport velocity and frequency of coalescence are measured and correlated with the operating conditions. Considering the important role of δ on downstream behavior, the Strouhal number, Sr, for various exit conditions is generally defined by taking δ as the characteristic length. A single correlation for the proposed Sr is obtained independent of different exit conditions.


[Abstract] After stroke and brain contusion, serum proteins extravasate into nerve tissue through disrupted blood-brain barrier (BBB). Because extravasations of serum proteins result in vasogenic brain edema, serum albumin level in the brain is an indicator of BBB disruption and brain edema after brain insults. In this protocol, extravasation of endogenous albumin is measured in the damaged mouse brain, which would be valuable in the evaluation of vasogenic brain edema formation (Michinaga et al., 2014).


The effect of crude protein (CP), amino acid (AA), and dietary electrolyte balance (DEB) were evaluated on blood parameters, carcass traits, and broiler performance under heat stress (29-34°C). A total of 540 male chickens (Ross 308) were allocated to 12 diets with factorial arrangement 2 × 2 × 3, using a completely randomized design with three replicates of 15 chickens in grower (13 to 26 days) and finisher (27 to 42 days) periods. and 120, 220, and 320 mEq kg-1 DEB. The level of 21% CP increased body weight gain (BWG) and decreased feed conversion ratio (FCR) at grower period (p < 0.05). In contrast, 20% CP level decreased BWG and increased FCR at finisher period (p < 0.05). Further, 20% CP level reduced blood sodium and blood electrolyte balance (p < 0.05). The highest blood electrolyte balance was achieved by DEB 320 mEq kg-1 diet (p < 0.05). Broiler response to DEB in heat stress depended on the age of bird, length of exposure to high temperature and CP level of the diet. Under heat stress (29-34°C), the 21% CP level at grower period and 17% CP level at finisher period improved broiler BWG and FCR.


The objective of the paper is to provide an estimative of the impacts that changes in international prices of agricultural commodities will have on income distribution and poverty in Brazil. To do so, a Social Accounting Matrix is constructed and applied, using a Leontief-Miyazawa model framework. The SAM is defined for 40 products, and households are allocated into 10 groups, being 6 agricultural and 4 urban. Demand elasticities (price and income) for the products defined in the SAM are considered, as well as limitations on the supply of agricultural inputs. The results indicate that a 50% reduction in tariffs across the board, by all countries and for all products, will produce minor impacts in Brazil: national GDP would increase by up to 1.6%, and the impacts on poverty and income inequality, although positive, would be very small.


Purpose
Detecting O2 gas in a confined space at room temperature is particularly important to monitor the work process of precision equipment. This study aims to propose a miniaturized, low-cost, mass-scale produced O2 sensor operating around 30°C.

Design/methodology/approach
The O2 sensor based on lanthanum fluoride (LaF3) solid electrolyte thin film was developed using MEMS technology. The principle of the sensor was a galvanic cell H2O, O2, Pt | LaF3 | Sn, SnF2 |, in which the Sn film was prepared by magnetron sputtering, and the LaF3 film was prepared by thermal resistance evaporation.

Findings
Through pretreatments, the sensor's response signal to 40% oxygen concentration was enhanced from 1.9 mV to 46.0 mV at 30°C and 97.0% RH. Tests at temperatures from 30°C to 50°C and humidity from 32.4% RH to 97.0% RH indicated that the output electromotive force (EMF) has a linear relationship with the logarithm of the oxygen concentration. The sensitivity of the sensor increases with an increase in both humidity and temperature in the couple mode, and the EMF of the sensor follows well with the Nernst equation at different temperatures and humidity.

Practical implications
This research could be applied to monitor the oxygen concentration below 25% in confined spaces at room temperature safely without a power supply.

Originality/value
The relationship between temperature and humidity coupling and the response of the sensor was obtained. The nano-film material was integrated with the MEMS process. It is expected to be practically applied in the future.


The aim of this study was to identify the geographical area for the cultivation of sesame (Sessamus indicum L) in Argentina, as a source of food or raw material to produce biofuels. To define the agroclimate for sesame in Argentina, we took into account limiting ambient temperature and required rainfall. Agroclimatic indices were calculated from the climate database of the Institute of Climate and Water of INTA, for the period 1971-2000. Each agroclimatic index was represented in a map and the overlapping of the different maps defined the agroclimate of the species in Argentina. The final map shows the surface with optimal conditions for sesame from the hydrological point of view, limited by the isohyet of 440 and 600 mm and the limit of 200 mm. As long as temperature is adequate, irrigation might extend even further the potential area for the cultivation of sesame in Argentina.


Received: 8 August 2019 Accepted: 17 November 2019 In the era of big data, it is of great significance to retrieve the semantic features from images by big data technique. However, most semantic query models perform poorly in actual images, which are distributed heterogeneously. Image ontology mapping provides a solution to the problem. This paper applies the H-Match algorithm to find the mapping relationship between image ontologies in peer-to-peer (P2P) environment, and rewrite user queries for heterogeneous image ontologies. The H-Match algorithm was developed under the framework called Helios evolving interaction-based ontology knowledge sharing (Helios). The weights of semantic annotation were calculated by a novel method, involving word frequency, position and feedback. The research results have great application potentials in various fields.


Shooting and Bouncing Ray Method (SBR) combined with the Physical Diffraction Theory (PTD) was adopted to calculate the near-fields composite scattering between target and sea surface. The radiation field of the horn antenna was simulated and used as the incident wave. The influence of the distance between composite model and antenna, wind speed as well as the antenna beam on the near-field scattering characteristic was studied from near-field RCS. The calculated results show that the characteristics of the near field are more complex, the incident wave cannot be regarded as plane wave and the effects of the antenna pattern on near-field scattering cannot be ignored.


■ Pain of deep and visceral origin is the most common form of pain produced by diseases. In contrast to the welllocalized and generally acute cutaneous pain, deep and visceral pain are aching, ill-localized and of chronic evolution. There is still no agreement on whether visceral pain is referred to the surface of the body or is simply vaguely localized by the higher centers of the nervous system. Some viscera are insen¬ sitive to noxious stimuli whereas others are extremely sensi¬ tive to them. The phenomenon of referred pain has been attri¬ buted to the convergence of visceral and somatic afferent fibers onto the same pool of sensory neurons in the spinal cord and subsequent cutaneous localization by the upper centers of the brain. There is no electrophysiological evidence of the exis¬ tence of specific visceral nociceptors. Some visceral afferent fibers enter the spinal cord via the ventral roots. Studies in the spinal cord have shown convergence of visceral and cu¬ taneous afferent fibers onto interneurons and neurons project¬ ing through several sensory ascending pathways including the spinothalamic tract. No pure visceral pathway has so far been found in the spinal cord. Data on the central nervous system representation of visceral information is scarce and inconclusive.


We present an 84‐year‐old Caucasian man (Fitzpatrick classification: skin type II) with microcystic adnexal carcinoma (MAC) on his left cheek and a 15‐year history of recurrent squamous cell carcinoma (SCC) of the head, treated with numerous surgical interventions and multiple palliative 60‐Gy radiation therapy.


The Bjorken sum rule and R ratio are constructed to $O(a^4)$ in the Landau gauge in the three momentum subtraction schemes of Celmaster and Gonsalves. We aim to examine the issue of convergence for observables in the various schemes as well as to test ideas on whether using the discrepancy in different scheme values is a viable and more quantum field theoretic alternative to current ways of estimating the theory error on a measureable.


A biological method for the determination of small quantities of toxic compounds in sea water using Chlamydomonas as an indicator organism is described. The method is sufficiently accurate for concentrations in the region of 5 × 10−3 p.p.m. The value of the method is its applicability to a range of toxic compounds for which no convenient methods of estimation exist, particularly in low concentrations.

The technique has been applied to the measurement of leaching rates of potential antifouling compositions.


The reaction of an aqueous slurry of HgI2 and an acetone solution of (Et3S)I (molar ratio 1:2) gives the title compound, [(C2H5)3S]2[HgI4], which contains discrete pyramidal Et3S+ and tetrahedral HgI42− ions. The bond distances of the anion (Hg1—I1 and Hg1—I2) are 2.780 (1) and 2.790 (1) A.


In the title one-dimensional coordination polymer, [Cu(SiF6)(C3H4N2)4]n, the CuII atom is coordinated by two hexafluoridosilicate F atoms and four pyrazole N atoms in a distorted trans-CuF2N4 octahedral environment. The dihedral angle between the planes of the pyrazlole rings in the asymmetric unit is 74.4 (3)°. The hexafluoridosilicate dianion acts as a bridging ligand, connecting the CuII atoms into a [1-10] chain. The Cu and Si atoms lie on special positions with 2/m site symmetry. In the crystal, intrachain N—H⋯F hydrogen bonds occur and weak C—H⋯F interactions link the chains.


Based on the present background of connecting vocational education and undergraduate education in the system of modern vocational education, the paper analyzes the current domestic exploration for the mode of constructing the connection between vocational and undergraduate education and puts forward the rational thinking about the connection the system of modern vocational education.


Research Institute for Solid State Physics and Optics, P.O. Box 49, H-1525 Budapest, Hungary(Dated: 8 April 2003)Antiferromagnetic Heisenberg spin chains in a sufficiently strong magnetic field are Luttinger liq-uids, whose parameters depend on the actual magnetization of the chain. Here we present precisenumerical estimates of the Luttinger liquid dressed charge Z, which determines the critical expo-nents, by calculating the magnetization and quadrupole operator profiles for S = 1/2 and S = 1chains using the density matrix renormalization group method. Critical amplitudes and the scat-tering length at the chain ends are also determined. Although both systems are Luttinger liquidsthe characteristic parameters differ considerably.


AbstractThe yield-line method provides a powerful means of rapidly estimating the ultimate load that can be carried by a reinforced concrete slab. The method can reveal hidden reserves of strength ...


Convergence of the spherical means (here is the characteristic function of a compact subdomain and is the radius of a ball in the frequency range) at a point , (where is the boundary of ), can be characterized by the convergence exponent . In the case when for and each as , is the least upper bound of . The question of the dependence of the quantity on the position of the point and the geometry of the hypersurface is studied. If is smooth and (here is the focal surface of ), then it is shown that irrespective of . A complete description of for domains with boundary in general position and is given on the basis of the theory of singularities. The question of the dimension of the divergence region (where the spherical means diverge as ) is considered. It is shown that for , while for there exist hypersurfaces in general position such that .


The notion of contracts play an important role since the beginning of humankind. Technological advances and the globalization have increased the use of contracts in electronic transactions. Therefore, verification of contracts has become extremely important to guarantee properties and agreements. Some formalisms are used as the basis to represent electronic contracts such as deontic and dynamic logics. Formal models and computational support allow to attain more precise results on checking electronic contracts. This work proposes an approach to represent appropriately multi-party contracts by means of suitable formalisms and also to automatically verify properties in contracts of this nature.


A design method of launch acceptability region(LAR) parametric model for guided munitions based on response surface modeling(RSM) was proposed.A polygon of n-vertices was defined to represent the LAR geometric shape,and a mathematical model of LAR was set a group of quadratic polynomials.A number of numerical simulation experiments based on six degree-of-freedom(DOF) model were designed to generate the training data sets and verification data sets.The experimental points corresponding to the training data sets were designed by D-optimal design,and the coefficients of parametric model were determined by a multiple regression analysis of the training data sets.The verification data sets were used to verify whether LAR generated using the fitted coefficients meets the defined criteria,and the experimental points were designed using Sobol sequences.The simulated results show that the designed parametric model could provide an acceptable accuracy of the LAR calculation and effectively reduce the complexity of the LAR calculation program.


A patient presenting syncope and convulsions was shown to have spontaneous attacks of ventricular standstill without preceding or subsequent partial heart block and with the auricles beating regularly throughout. Carotid sinus pressure reproduced one such attack. This is a demonstration of nervous control in the heart below the auriculoventricular node and perhaps in the ventricle itself. Cookson's term "paroxysmal ventricular standstill" is uniquely fitting. The presence of right bundle branch block raises the question of a lesion affecting both the left and right branches of the bundle of His.


Purpose To describe the operative technique and clinical effects of three-column enhanced percutaneous vertebroplasty used to treat Kummell's disease. Methods From April 2017 to April 2020, 39 patients with Kummell's disease were treated via three-column enhanced percutaneous vertebroplasty. There were 12 males and 27 females of average age 70.23 ± 7.41 years. The operative time, volume of bone cement injected, and intraoperative cement leakage were recorded. The patients were re-examined postoperatively. The VAS was used to evaluate low back pain and the ODI score to evaluate improvement in the quality-of-life. Results All patients were successfully operated upon; the average operation time was 35.1±4.7 min and average volume of bone cement injected 4.5±0.92 mL. Five cases exhibited bone cement leakage during operation, two into the intervertebral disc and three into the anterior upper margin of the vertebral body. No leakage into the vertebral canal occurred. The average hospital stay was 2.50±0.86 days. The VAS score before operation was 7.47±0.24, but low back pain symptoms were significantly relieved after operation (P < 0.05). The VAS scores at 1 day and 1, 3, 6, and 12 months after operation were 2.91±0.09, 2.04±0.07, 1.59±0.05, 1.28±0.15, and 0.8±0.18, respectively. The preoperative ODI score was 72.97±1.45 and significantly decreased postoperatively (P < 0.05), being 30.08±1.79 at 1 day, and 25.35±0.94, 23.19±1.76, 20.49±0.65, and 20.05±0.58 at 1, 3, 6, and 12 months after operation respectively. Conclusion Three-column enhanced percutaneous vertebroplasty effectively treats Kummell's disease. The surgical trauma is low, recovery rapid, and bone cement fixation firm, especially in patients with stage I and II disease.


Laser-assisted atom probe tomography (APT) was used to measure the indium mole fraction x of c-plane, MOCVD-grown, GaN/In(x)Ga(1-x)N/GaN test structures and the results were compared with Rutherford backscattering analysis (RBS). Four sample types were examined with (RBS determined) x = 0.030, 0.034, 0.056, and 0.112. The respective In(x)Ga(1-x)N layer thicknesses were 330 nm, 327 nm, 360 nm, and 55 nm. APT data were collected at (fixed) laser pulse energy (PE) selected within the range of (2-1000) fJ. Sample temperatures were = 54 K. PE within (2-50) fJ yielded x values that agreed with RBS (within uncertainty) and were comparatively insensitive to region-of-interest (ROI) geometry and orientation. By contrast, approximate stoichiometry was only found in the GaN portions of the samples provided PE was within (5-20) fJ and the analyses were confined to cylindrical ROIs (of diameters =20 nm) that were coaxial with the specimen tips. m-plane oriented tips were derived from c-axis grown, core-shell, GaN/In(x)Ga(1-x)N nanorod heterostructures. Compositional analysis along [0 0 0 1] (transverse to the long axis of the tip), of these m-plane samples revealed a spatial asymmetry in charge-state ratio (CSR) and a corresponding asymmetry in the resultant tip shape along this direction; no asymmetry in CSR or tip shape was observed for analysis along [-1 2-1 0]. Simulations revealed that the electric field strength at the tip apex was dominated by the presence of a p-type inversion layer, which developed under typical tip-electrode bias conditions for the n-type doping levels considered. Finally, both c-plane and m-plane sample types showed depth-dependent variations in absolute ion counts that depended upon ROI placement.


Recently,
 good agreement was found between experimental and phase space theory (PST) results concerning the recoil energy and angular distributions in the products of the reactions O(1D, 3P)+ICH3→OI+CH3. The details
 of the calculations are presented in this work. Three models are proposed which assume different degrees
 of intramolecular vibrational redistribution (IVR) for the intermediate complex OICH3. It turns
 out that the reaction O(1D)+ICH3→OI+CH3 might proceed through an osculating complex with a sufficiently short lifetime
 to excite only the vibrational modes of the complex which correlate with the stretching mode
 of OI and the umbrella mode of CH3. Conversely, reaction O(3P)+ICH3→OI+CH3 proceeds via
 intersystem crossing
 between triplet and singlet surfaces through a long lifetime intermediate leading to an isotropic angular distribution of the products. Nevertheless, in opposition to the reaction O(1D)+ICH3→OI+CH3,
 it appears
 difficult
 in this case to deduce
 the efficiency of the IVR process from the results obtained.


It is widely recognized that the sensitivity of hydrophones used to measure medical diagnostic ultrasound fields should be uniform over several octaves above the center frequency (i.e., above the mean of the upper and lower −3 dB frequencies in the transmitted acoustic-pressure spectrum). However, a bandwidth extending to at least ten times below the diagnostic pulse-center frequency is needed for accurate (error ≈5%) measurement of the peak rarefactional pressure. Since at present it is not common for manufacturers of medical-use hydrophones to provide sensitivity information below 1–2 MHz, a study was undertaken to determine these low-frequency sensitivities. The technique uses broadband, plane-wave pressure pulses generated by electrical short-pulse excitation of a thick piezoelectric ceramic disk. The hydrophone response is calculated from measurements of the source transducer and hydrophone-voltage waveforms. The frequency responses of both needle-type and spot-poled membrane polymer hydrophones were...


Nowadays, SF6 circuit breaker is irreplaceable protection equipment in ultra-high voltage power systems. To improve the breaking performance, the physical-mathematical model of nozzle arc has been continuously explored. At present, the commonly used model is the magnetohydrodynamic model based on Navier Stokes equation, which is nonlinear and difficult to solve. A new nozzle arc model based on lattice Boltzmann method (LBM) is proposed in this paper. The heat source term and boundary conditions in this model are treated to make it suitable for arcing process. This model has been used to simulate the arcing process of a 252kV high-voltage SF6 circuit breaker. The temperature distribution are obtained in the arc extinguishing chamber. The variation in temperature with arc current is given along arc radius. Simulation results perfectly verify the feasibility of the arc model based on LBM.


Uses literary examples and case materials to illustrate themes of (1) the power of existential roots, (2) the avoidance of personal responsibility, (3) the denial of reality, (4) the terror of individuation, (5) the fear of intimacy, and (6) the quest for unmingled pleasure. Offers therapeutic strategies for dealing with each of these themes and in doing so draws especially on the theories of leading family therapists.


This study presents a wide-swing circuit which is insensitive to device mismatch in CMOS technology. The wide-swing design is used to increase the output resistance, maximize the voltage-signal swings, and improve the current matching. The error current is greatly reduced by providing an additional mirrored current in the referenced circuit. A start-up circuitry is also included, only the circuit in the case that all currents in the loop are zero. All the bipolar-junction transistors are laid out using the p-substrate PNP structure. Analytic results indicate that the proposed circuit is insensitive to device mismatch, and provides a stable bias current accurately.


TiO2 composite photocatalysts with doping amounts of Ce (0.5%Ce/TiO2, 1%Ce/TiO2, 2%Ce/TiO2, 3%Ce/TiO2 and 5%Ce/TiO2)were synthesized via a sol-gel method.The structure and morphology of the prepared composites were characterized by XRD, SEM, DRS, XPS. At the same time, the photocatalytic effect of the composite on rhodamine B (RhB) solution under simulated visible light irradiation was explored.The results indicated that the crystal of powder catalyst was anatase type TiO2, and the directional aggregation of Ce/TiO2 composite photocatalyst showed ice cream flowers-shaped structure.The photocatalysis activity was the best when Ce doping amounts were 3%.The degradation rate of RhB was 96% in 120 min, which was 50% higher than pure TiO2.Hydroxyl radical (⋅OH) played a leading role in the whole photodegradation reaction system, and its contribution rate was about 66.4%.


After fish fat was removed organotin compounds were alkylated with ethylmagnesium bromide. Extracted tetrasubstituted tin compounds were determinated by gas-liquid chromatography with a flame photometric detector (detection limit: 0.2 ng for each organotin compound). Analysis of fish samples, showed accumulations of organotin compounds, suggesting that marine pollution with these tin compounds, is prevalent over Japan


Lipoprotein(a) [Lp(a)], a low‐density lipoprotein (LDL)‐like particle, has been independently associated with increased cardiovascular disease (CVD) risk in various populations, such as postmenopausal women. The purpose of this narrative review is to present current data on the role of Lp(a) in augmenting CVD risk in postmenopausal women and focus on the available therapeutic strategies.


An outline is given of an algorithm that may be used in the design of rate feedback systems that satisfy the conditions in the conjecture of R.S. Bucy et al. (1989). Two low-order examples demonstrate the applicability of the algorithm. A finite design procedure is described for the general minimax system.<<ETX>>


Abstract The purpose of this paper is to study a chi-square-type distribution who degrees of freedom are geometric random variables in connection with weak limiting distributions of geometric random sums of squares of independent, standard normal distributed random variables. Some characteristics of chi-square-type random variables with geometrically distributed degrees of freedom including probability density function, probability distribution function, mean and variance are calculated. Some asymptotic behaviors of chi-square-type random variables with geometrically distributed degrees of freedom are also established via weak limit theorems for normalized geometric random sums of squares of independent, standard normal distributed random variables. The rates of convergence in desired weak limit theorems also estimated through Trotter's distance. The received results are extensions and generalizations of several known results.


Part 1 Rise of science-related technology: introduction evolutionary theory in economics and technical change process innovations materials innovations product and system innovation paradigm change. Part 2 Innovations and the firms: the microeconomics of innovation success and failure, the role of marketing and user-producer networks innovation, size of firm, economies of scale and scope uncertainty, project evaluation and finance of innovation, management strategy and theory of the firm. Part 3 Macroeconomics of innovation - science, technology and economic growth globalization and multinational corporations underdevelopment and catching up. Part 4 Innovation and public policies: market failure and aspects of public support for innovation technical change, employment and skills environmental issues technological assessment. Appendix: measurement and definitions.


he articles with which Lucy Allais made her name as Kant expert in the mid- to late nineties have now been updated and partially rewritten for her first monograph, which deals with all the aspects of Kant's controversial doctrine of idealism, including her much-discussed reading of Kant as a nonconceptualist about intuition1 – one perhaps wonders why a book on Kant's idealism also discusses the topic of non-conceptualism, but on re-reading her arguments in the integrated context of the book, it occurred to me that Allais's nonconceptualist interpretation of Kant is very much tied in with her take on Kant's idealism. the book is first-rate example of Kant scholarship. It makes for an exciting reading and offers many insights and openings for new avenues of ap-proach to various aspects of Kant's philosophy. It one of the few books on Kant which will be referenced and consulted many years hence; in that sense it is comparable to Henry Allison's classic Kant's Transcendental Idealism: An Interpretation and Defense .2 Unlike Allison's magnum opus though, Allais's book is much more philosophically reconstructive and much less a close reading of the text. Of course, Allais pays due attention to the textual evidence for and against her interpretation, but she also offers an insight from contemporary philosophical perspectives that have prima facie nothing to do with Kant. This is both an advantage and a problem, as I shall point out further below. Abstract In this critical notice of Lucy Allais's recent monograph on Kantian idealism I focus on her refutation of phenomenalism, which is important for her metaphysical-realist reading of appearances. She provides 7 reasons for rejecting phenomenalist readings of Kant's idealism about appearances. I argue that none of these reasons are compelling. Notwithstanding the many valuable features of Allais's interpretation of Kant's idealism overall, her effort to de-mentalise Kantian appearances is in my view precisely the wrong move.


The right promotion strategy in promoting higher education is very necessary in addition to introducing about the university, promotions are also carried out to attract the interest and talents of prospective students in continuing to the higher education, especially at UNAKI Semarang. Implementing the Association Rule method and the FP-Growth algorithm in the promotion strategy is the way to find out what right rules or patterns in determining a more accurate promotional strategy. Research used data from prospective students for the last three years, 2016-2018, where in the data the researchers focused more on testing variables or items. The variables used are Region of Origin, Preferred Study Program, previous majors in SMA/SMK, and Parents' Occupation Keyword-component; association rules, frequent itemset, FPGrowth algorithm


The rules of ice-shedding characteristics were acquired by simulation tests,and various span configurations as well as ice-shedding mode were taken into consideration.Furthermore,numerical computation was done according to the test conditions.Good agreement between the computational and test results was obtained which proves the validity of both the test and numerical methods.Then a 3DOF(degree of freedom) dynamic model of multi-span line suitable for analyzing UHV ice-shedding was presented.The influential factors including multi-span configuration,span length,number of spans per line section,and mechanical parameters of conductor are studied.The ice-shedding height of UHV was analyzed when the icing thickness was 15 mm.Results show that interphase conductors of UHV double circuit transmission line needn't have horizontal displacement at the condition of 15 mm ice thickness and below.When the ice-shedding from the conductor happens,the lines can also work safely.


Abstract
In the initial phase of implementing the hospital information system at our University Hospitals the presentation of observation results on the wards has been realized. In the Result Reporting System (RR System), the patient administration data and observation results are merged and stored in a central database. Clinical staff can access the majority of observation results in the RR System at least three hours earlier than conventionally. This time saving is ensured as long as the dataflow through the components of the hospital communication system runs free of failures. This paper deals with the systematic monitoring of the communication system.


This paper describes a methodology for estimating the numerical errors in real-time simulation based on comparing two real-time simulations, one with the nominal integration step size and the second with an augmented step size. Accurate interpolation formulas are then used to convert the outputs from the second simulation to outputs at the discrete times for the first simulation. This permits a direct computation of the difference between the two simulations at common discrete times. Assuming that the dynamic errors vary as hk, where h is the integration step size and k is known, a simple formula can then be used to calculate the deviation of either simulation from the solution for zero step size. While only approximate, this procedure results in dynamic error estimates that are surprisingly accurate, as demonstrated in the paper in example simulations that use both single and multi-rate integrations. It turns out that three simulations, each with a different integration step size, can be used to estimate the exponent k in the dependence of dynamic errors on hk. This in turn allows programming errors, such as the inadvertent introduction of a one-frame delay within the simulation code, to be identified. The author feels that the methodology described in the paper can play a major role in optimizing as well as verifying the dynamic fidelity of real-time, hardware-in-the-loop simulations.


Background: Yuvanpidika can be correlated with acne vulgaris of modern medicine due to the resemblance of symptoms. It is not a serious health problem, but it affects the social and emotional health of an individual. It is self-limiting but requires treatment to avoid scarring and relapse. Aim and Objectives: This comparative research was carried out with the aim to evaluate the efficacy of Lodhradi Lepa with and without Arogyavardhini Vati in the management of Yuvanpidika. Materials and Methods: A total of 30 patients between the ages of 16 and 36 years of both sexes with typical symptoms of Yuvanpidika were selected from Kayachikitsa outpatient department. They were divided equally into two groups by lottery method. Lodhradi Lepa was topically applied with rose water to patients in Group A twice daily, whereas Group B was given Arogyavardhini Vati (500mg) twice a day along with Lodhradi Lepa for 30 days. Pain, itching, burning sensation, swelling, redness, and the number of papules were assessed before and after treatment in both groups. Results: In this study, moderate, mild, and poor improvements were observed in five (33.33%), two (13.33%), and eight (53.33%) patients of Group A, respectively, whereas in Group B, moderate, mild, and poor improvements were observed in eight (53.33%), four (26.66%), and three (20%) patients, respectively. Marked improvement and complete remission were not observed in this study. This might be due to a short duration of treatment. Conclusion: This study proved that the use of Lodhradi Lepa and Arogyavardhini Vati is effective in the treatment of Yuvanpidika. But combined treatment is more beneficial and combination of various protocols and formulations need to be adopted for better results.


Tralfamadore is a platform for debugging and analyzing whole software systems, from the operating system up. Tralfamadore employs a novel mechanism for analysis in which, rather than interrupting and examining the system under test as it runs, the system is instead run to completion untouched then examined posthoc. The system under test is run in a virtual machine which records its execution; analysis and debugging tools are then applied to the recorded execution trace data. Tralfamadore thus permits travelling both forward and backward through time while debugging, debugging systems that would not normally be able to be halted (such as those that communicate with time-sensitive external systems), and accurately reproducing a view of a system's execution even if that system has (maliciously or accidentally) corrupted its internal state. Tralfamadore also has a number of other potentially-interesting applications in aspect-oriented programming, forensic analysis, dynamic analysis, and customer-site bug reporting.


In this article, we did a bibliographic search with the objective of understanding the learning process described by the Neurosciences research and bringing it closer to the characteristics arising from the development of Mathematical Modeling activities. In this sense, we highlight the stimuli (meaning, motivation and attention), the conservation process (repetition, elaboration and consolidation) and the executive functions involved in the process of learning information according to neuroscientific works, and then we highlight the characteristics arising from the development of activities Mathematical Modeling according to Barbosa (2001) and Almeida and Dias (2004). In the approach, we perceived evidences that the actions necessary for the development of Mathematical Modeling activities permeate the entire learning process according to what the Neurosciences advocates.


Network organizations widely multiply in health care systems whereas they didn't fulfil their objectives. We support that the unsuited implementation of French health care networks limits their contributions however theoretically proved they are. In a first part, we refer to different theoretical frameworks in order to draw network's potential contribution to the efficacy and the equity of health care. Standard Economics establish the appropriateness of networks grounded on competition, contracts and incentives (chapter 1). Then we refer to Economics of Convention and to an interpretative rationality hypothesis. On this basis we describe networks as alternative organizations - different both from market and from hierarchy -, built on convention rules and improving cooperation, trust and deliberation between their members. In a second part, we review existing networks in France (chapter 3). We underscore their limits, which are widely due to the complex running of those horizontal organizations confronted with the compartmentalization of the health care system. In chapter 4 we refer to the theoretical analyses developed in the first part, to contribute to an improved implementation of French health care networks. We firstly specify the details of an evaluation tool adapted to networks. Then, we advocate a regionalized bipartite management of French health care networks: an external governance delegated to an unified regional regulator, that favours incentive contracts, and an internal regulation based on trust and cooperation between the members of the organization.


The importance of the Internet for society is increasing. To ensure a functional Internet, its routers need to operate correctly. However, the need for router flexibility has led to the use of software-programmable network processors in routers, which exposes these systems to data plane attacks. Recently, hardware monitors have been introduced into network processors to verify the expected behavior of processor cores at run time. If instruction-level execution deviates from the expected sequence, an attack is identified, triggering processor core recovery efforts. In this manuscript, we describe a scalable network processor monitoring system that supports the reallocation of hardware monitors to processor cores in response to workload changes. The scalability of our monitoring architecture is demonstrated using theoretical models, simulation, and router system-level experiments implemented on an FPGAbased hardware platform. For a system with four processor cores and six monitors, the monitors result in a 6 percent logic and 38 percent memory bit overhead versus the processor's core logic and instruction storage. No slowdown of system throughput due to monitoring is reported.


This paper proposes a novel approach to solve pair-wise registration problem which aligns different pointclouds taken from the same object or scenario at different angles. The new method uses points as a searching medium replacing convention six-dimensional one. By doing this, the number of searching dimensions is significantly reduced. Using the same number of searching loops, the new method results in a higher convergence rate into global optimal results. The approach is successfully implemented in a hybrid registration strategy which combines Iterative Closest Point (ICP) as a local aligning tool and a global searching algorithm such as state-of-the-arts including Simulated Annealing, Particle Swarm optimization, Differential Evolution or a recently developed adaptive Differential Evolution algorithm, ISADE. The accuracy and robustness of the new method over the conventional approach are proved through various experiments on different datasets.


Abstract Fisheries managers often assess body condition using relative weight (W r) because it provides a comparative measure of fish plumpness among individuals and populations. However, it is not known whether the morphological information that W r summarizes reflects physiological measures, such as relative lipid reserves, in rainbow trout Oncorhynchus mykiss. The purpose of this study was to determine whether swimming activity affects either the W r or proximate body composition of juvenile (total length, 170–260 mm) rainbow trout. When rainbow trout from a hatchery were fed ad libitum for 147 d, inactive (no current) and active (15 cm/s current velocity) fish did not differ in Wr. However, inactive rainbow trout maintained relatively constant lipid levels, whereas active fish declined in lipid content. Relative weight may provide a comparable measure of body form, but it is not an accurate index of lipid content between active and inactive rainbow trout fed an excess ration. For assessing the physiol...


Selective analysis revealed the insufficient coverage of children aged up to 3 years with immunization against diphtheria, pertussis and tetanus in Baku, as well as lagging behind the established vaccination schedule. The absence of the prophylactic immunization of children during first 3 years of their life was mainly due to such medical contraindications as acute respiratory diseases, neurological diseases and various dermal manifestations. At the same time no sparing methods of immunization were used.


George Lindbeck is unabashed about the debt he owes to Ludwig Wittgenstein concerning his cultural-linguistic theory of religion and the derivative theological method. He admits that, "Wittgenstein's influence. . has served as a major stimulus to my thinking.'" Nevertheless, Lindbeck rarely makes clear where this stimulus has been appropriated. It will be the burden of this essay to demonstrate some ways in which Wittgenstein's influence is evident in Lindbeck's theory as explained in his book, The Nature of Doctrine. We will begin with a brief sketch of some crucial Wittgensteinian points and then see how Lindbeck has attempted to appropriate them vis-a-vis the question of religious truth 2 We will then conclude with some remarks on how this relates to Lindbeck's ecumenical interests. lANGUAGE FOR WIlTGENSTEIN Wittgenstein has argued against theories of language based on referentialism . He opens his Philosophical investigations with a quotation from St. Augustine's Confessions in which Augustine describes that he learned what things were called based on the utter ances of his elders and their pointing at the corresponding objects. Over time, he came to understand how these utterances were to be strung together into sentences and thereby constitute a language. This way of understanding language as referential (that is, as making reference to things in reality) became the object of Wittgenstein's critique. The problem is not that referentialism is outright false but that it fails to account for the variety of functions words serve. This is why he adds, "Augustin e does not speak of there being any differences between kinds of words."3 To be sure, some aspects of language actually do function this way but certainly not all-or even most of them. Wittgenstein demonstrated that a purely referential language is quite incon ceivable by showing the various functions of words in even a very simple example.


The Paranatinga kimberlite province is located in Mato Grosso, central Brazil (14°S, 54°W). It was emplaced on the southern margin of the Amazonas craton, to the north of the Parana basin and consists of approximately forty pipes, distributed over an area of -4,000 km2. New petrological and geochemical data from nine of these intrusions will be presented. The Brazilian kimberlites analysed to date are isotopically intermediate between Group I and Group II South African kimberlites, possibly reflecting discrete differences in their genesis. Further analyses are required to establish whether these intermediate isotopic compositions are a function of differing post-genesis interaction, or a fundamental feature of their source.


Introduction: Neoplastic polyps of the gallbladder are commonly asymptomatic. However, advances in radiologic modalities and their growing use for various clinical indications have increased the number of gallbladder polyps being diagnosed and reported. Yet, due to lack of unified terminology and reporting criteria, the body of scientific evidence regarding their classification and management is scarce and even sometimes controversial. The plethora of terminology used in scientific literature to describe these lesions includes "pyloric gland adenoma," "tubulopapillary adenoma," and "biliary adenoma". Even though this diverse group of lesions shares histological and immunohistochemical characteristics, they are distinct entities with different cellular lineages and a spectrum of dysplasia which makes their prognosis different. Histologically, these lesions are classified as the gastric pyloric gland, gastric foveolar, intestinal, and biliary, with the pyloric subtype being the most common lesion (82%). Adsay et al. are the first group of investigators who proposed the unified terminology of intracholecystic papillary-tubular neoplasms (ICPNs) to describe neoplastic polyps of the gallbladder. They used the size of over 1 cm as an inclusion criterion as this size has been used in other lesions of the pancreatobiliary system like intraductal papillary mucinous neoplasms (IPMN). In the surgical literature, patients with polyps of over 1 cm are often being elected to go through cholecystectomies. Adsay and colleagues used 25% and 75% tubule or papillary formation as cutoff points to categorize ICPNs


This paper raises preaching activities in the Muhammadiyah Central Office environment that have been realized. However, obstacles in the field there are still many that do not understand the practice of worship based on Tarjih Muhammadiyah so that the recitation program in the environment carried out by field IV is routinely carried out, response the recitation participants are right, but there are still obstacles to be faced. The understanding in worship is not deep enough, so it requires guidance, guidance, and training. The writing methodology is observation, interviews, and documentation, which the author directly does at the Muhammadiyah University Palembang Headquarters. With this paper, the authors can see the implementation of da'wah, which is carried out, and the factors that affect the implementation of da'wah in the Muhammadiyah Palembang headquarters environment.


The "İllness Intrusiveness Ratings Scale (IIRS)" is a useful, easy-to-apply tool that measures the degree of illness-induced disruptions in the 13 different aspects of life. The main aim of this study is to examine the validity and reliability of the Turkish version of IIRS and provide a new tool to investigate the impact of chronic illnesses in the Turkish population. A total of 376 patients with hypertension, diabetes, and/or osteoarthritis were recruited in this study. Patients completed the survey that consisted of the sociodemographic data, the Turkish translation of the IIRS, and the World Health Organization Quality of Life-Brief Form. The exploratory factor analysis yielded a three-factor structure, "instrumental," "intimacy," and "relationship and personal development," which accounted for 59.9% of the total variance. Confirmatory factor analysis verified the three-factor structure. The IIRS was inversely correlated with the physical, psychological, and social health domains of quality of life. Our findings corroborate the reliability and validity of the Turkish version of the Illness Intrusiveness Ratings Scale. It can be used by healthcare practitioners to measure the illness-induced disruptions of lifestyles, activities, and interests.


ABSTRACT Flunixin meglumine (FM) is a novel nonsteroidal anti-inflammatory drug for animals, which has antipyretic, analgesic, and anti-inflammatory effects. The drug, which was originally used to relieve inflammation in horses, musculoskeletal disorders, and pain, has been approved for use in endotoxemia, infectious diseases in swine, etc. A sensitive anti-FM monoclonal antibody 2H4 was prepared and used to develop an indirect competitive enzyme-linked immunosorbent assay and immunochromatographic strip assay for the detection of FM in milk. The complete antigen and coating antigen were conjugated with bovine serum albumin and ovalbumin, respectively. The monoclonal antibody 2H4, with a half inhibition concentration of 0.29 ng/mL, had a limit of detection of 0.432 ng/mL and a linear range of detection of 0.08664–0.97226 ng/mL. A sensitive and convenient immunochromatographic strip assay was developed with an FM cutoff value of 0.29 ng/mL. The developed methods were suitable for the detection of FM in milk.