text:
Lactic Acidosis
- Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias. The onset of metformin-associated lactic acidosis is often subtle, accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, somnolence, and abdominal pain. Metformin-associated lactic acidosis was characterized by elevated blood lactate levels (>5 mmol/L); anion gap acidosis (without evidence of ketonuria or ketonemia); an increased lactate:pyruvate ratio; and metformin plasma levels generally >5 mcg/mL.
- Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (eg, carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (eg, acute congestive heart failure), excessive alcohol intake, and hepatic impairment.
- Steps to reduce the risk of and manage metformin-associated lactic acidosis in these high-risk groups are provided in the full prescribing information.
- If metformin-associated lactic acidosis is suspected, immediately discontinue INVOKAMET®/ INVOKAMET® XR and institute general supportive measures in a hospital setting. Prompt hemodialysis is recommended.
Risk of Lower-Limb Amputation
- An approximately 2-fold increased risk of lower-limb amputations associated with canagliflozin, a component of INVOKAMET®/INVOKAMET® XR, was observed in CANVAS and CANVAS-R, two large, randomized, placebo-controlled trials in patients with type 2 diabetes who had established cardiovascular disease (CVD) or were at risk for CVD.
- Amputations of the toe and midfoot were most frequent; however, amputations involving the leg were also observed. Some patients had multiple amputations, some involving both limbs.
- Before initiating, consider factors that may increase the risk of amputation, such as a history of prior amputation, peripheral vascular disease, neuropathy, and diabetic foot ulcers.
Monitor patients receiving INVOKAMET®/INVOKAMET® XR for infection, new pain or tenderness, sores, or ulcers involving the lower limbs, and discontinue if these complications occur.
- Moderate to severe renal impairment (eGFR below 45 mL/min/1.73 m2), end stage renal disease (ESRD), or patients on dialysis
- Acute or chronic metabolic acidosis, including diabetic ketoacidosis
- History of a serious hypersensitivity reaction to canagliflozin or metformin, such as anaphylaxis or angioedema
WARNINGS and PRECAUTIONS
Lactic Acidosis: Postmarketing cases of metformin-associated lactic acidosis, including fatal cases, were reported. These cases had a subtle onset and were accompanied by nonspecific symptoms such as malaise, myalgias, abdominal pain, respiratory distress, or increased somnolence; however, hypothermia, hypotension, and resistant bradyarrhythmias have occurred with severe acidosis. Metformin-associated lactic acidosis was characterized by elevated blood lactate concentrations (>5 mmol/L), anion gap acidosis (without evidence of ketonuria or ketonemia), an increased lactate:pyruvate ratio; and metformin plasma levels generally >5 mcg/mL. Metformin decreases liver uptake of lactate, increasing lactate blood levels which may increase the risk of lactic acidosis, especially in patients at risk.
If metformin-associated lactic acidosis is suspected, general supportive measures should be instituted promptly in a hospital setting, along with immediate discontinuation. In INVOKAMET®/INVOKAMET® XR-treated patients with a diagnosis or strong suspicion of lactic acidosis, prompt hemodialysis is recommended to correct the acidosis and remove accumulated metformin. Hemodialysis has often resulted in reversal of symptoms and recovery.
Educate patients and their families about the symptoms of lactic acidosis and if symptoms occur instruct them to discontinue INVOKAMET®/INVOKAMET® XR and report these symptoms to their healthcare provider.
For each of the known and possible risk factors for metformin-associated lactic acidosis, recommendations to reduce the risk of and manage metformin-associated lactic acidosis are provided below:
Renal Impairment: Postmarketing metformin-associated lactic acidosis cases primarily occurred in patients with significant renal impairment. The risk of metformin accumulation and metformin-associated lactic acidosis increases with the severity of renal impairment because metformin is substantially excreted by the kidney. Obtain an eGFR before initiation and at least annually thereafter, and more frequently in patients at increased risk of renal impairment.
Drug Interactions: The concomitant use of INVOKAMET®/INVOKAMET® XR with specific drugs may increase the risk of metformin-associated lactic acidosis: those that impair renal function, result in significant hemodynamic change, interfere with acid-base balance, or increase metformin accumulation (eg, cationic drugs). Consider more frequent monitoring of patients.
Age 65 or Greater: The risk of metformin-associated lactic acidosis increases with the patient's age due to a greater likelihood of hepatic, renal, or cardiac impairment. Assess renal function more frequently in elderly patients.
Radiological Studies with Contrast: Administration of intravascular iodinated contrast agents in metformin-treated patients has led to an acute decrease in renal function and the occurrence of lactic acidosis. Stop INVOKAMET®/INVOKAMET® XR at the time of, or prior to, an iodinated contrast imaging procedure in patients with an eGFR of 45 to 60 mL/min/1.73 m2; in patients with a history of hepatic impairment, alcoholism, or heart failure; or in patients who will be administered intra-arterial iodinated contrast. Re-evaluate eGFR 48 hours after the imaging procedure, and restart INVOKAMET®/INVOKAMET® XR if renal function is stable.
Surgery and Other Procedures: Withholding of food and fluids during surgical or other procedures may increase the risk for volume depletion, hypotension, and renal impairment.
INVOKAMET®/INVOKAMET® XR should be temporarily discontinued while patients have restricted food and fluid intake.
Hypoxic States: Several postmarketing cases of metformin-associated lactic acidosis occurred in the setting of acute congestive heart failure. Cardiovascular collapse (shock), acute myocardial infarction, sepsis, and other conditions associated with hypoxemia have been associated with lactic acidosis and may also cause pre-renal azotemia. When such events occur, discontinue INVOKAMET®/INVOKAMET® XR.
Excessive Alcohol Intake: Alcohol potentiates the effect of metformin on lactate metabolism and this may increase the risk of metformin-associated lactic acidosis. Warn patients against excessive alcohol intake while receiving INVOKAMET®/INVOKAMET® XR.
Hepatic Impairment: Patients with hepatic impairment have developed metformin-associated lactic acidosis. This may be due to impaired lactate clearance resulting in higher lactate blood levels. Avoid use of INVOKAMET®/INVOKAMET® XR in patients with clinical or laboratory evidence of hepatic disease.
Lower-Limb Amputation: An approximately 2-fold increased risk of lower-limb amputations associated with canagliflozin, a component of INVOKAMET®/INVOKAMET® XR, was observed in CANVAS and CANVAS-R, two large, randomized, placebo-controlled trials evaluating patients with type 2 diabetes who had either established cardiovascular disease or were at risk for cardiovascular disease. In CANVAS, canagliflozin-treated patients and placebo-treated patients had 5.9 and 2.8 amputations per 1000 patients per year, respectively. In CANVAS-R, canagliflozin-treated patients and placebo-treated patients had 7.5 and 4.2 amputations per 1000 patients per year, respectively. The risk of lower-limb amputations was observed at both the 100-mg and 300-mg once-daily dosage regimens.
Amputations of the toe and midfoot (99 out of 140 patients with amputations receiving canagliflozin in the two trials) were the most frequent; however, amputations involving the leg, below and above the knee, were also observed (41 out of 140 patients with amputations receiving canagliflozin in the two trials). Some patients had multiple amputations, some involving both lower limbs.
Lower-limb infections, gangrene, and diabetic foot ulcers were the most common precipitating medical events leading to the need for an amputation. The risk of amputation was highest in patients with a baseline history of prior amputation, peripheral vascular disease, and neuropathy.
Before initiating, consider factors in the patient history that may predispose to the need for amputations, such as a history of prior amputation, peripheral vascular disease, neuropathy, and diabetic foot ulcers. Counsel patients about the importance of routine preventative foot care. Monitor patients for signs and symptoms of infection (including osteomyelitis), new pain or tenderness, sores, or ulcers involving the lower limbs, and discontinue if these complications occur.
- Hypotension: Canagliflozin causes intravascular volume contraction. Symptomatic hypotension can occur after initiating INVOKAMET®/INVOKAMET® XR, particularly in patients with an eGFR <60 mL/min/1.73 m2, elderly patients, patients on either diuretics or medications that interfere with the renin-angiotensin-aldosterone system, or patients with low systolic blood pressure. Before initiating INVOKAMET®/INVOKAMET® XR in patients with ≥1 of these characteristics who were not already on canagliflozin, volume status should be assessed and corrected. Monitor for signs and symptoms after initiating therapy.
- Ketoacidosis: Reports of ketoacidosis, a serious life-threatening condition requiring urgent hospitalization, have been identified in patients with type 1 and 2 diabetes mellitus receiving SGLT2 inhibitors, including canagliflozin. Fatal cases of ketoacidosis have been reported in patients taking canagliflozin. Before initiating INVOKAMET®/INVOKAMET® XR, consider factors in patient history that may predispose to ketoacidosis, including pancreatic insulin deficiency, caloric restriction disorders, and alcohol abuse. In patients treated with INVOKAMET®/INVOKAMET® XR, consider monitoring for ketoacidosis and temporarily discontinuing in clinical situations known to predispose to ketoacidosis (eg, prolonged fasting due to acute illness or surgery).
Acute Kidney Injury and Impairment in Renal Function: Canagliflozin causes intravascular volume contraction and can cause renal impairment. Postmarketing reports of acute kidney injury, some requiring hospitalization and dialysis, were reported; some reports involved patients younger than 65 years of age. Before initiation, consider factors that may predispose patients to acute kidney injury including hypovolemia, chronic renal insufficiency, congestive heart failure, and concomitant medications. Consider temporarily discontinuing INVOKAMET®/INVOKAMET® XR in any setting of reduced oral intake or fluid losses; monitor patients for signs and symptoms of acute kidney injury. If acute kidney injury occurs, discontinue promptly and institute treatment.
Canagliflozin increases serum creatinine and decreases eGFR. Patients with hypovolemia may be more susceptible to these changes. Renal function abnormalities can occur after initiation. Renal function should be evaluated prior to initiation and periodically thereafter. Dose adjustment and more frequent renal function monitoring are recommended in patients with an eGFR <60 mL/min/1.73 m2.
Hyperkalemia: Canagliflozin can lead to hyperkalemia. Patients with moderate renal impairment who are taking medications that interfere with potassium excretion, such as potassium-sparing diuretics, or medications that interfere with the renin-angiotensin-aldosterone system are at an increased risk of developing hyperkalemia.
Monitor serum potassium levels periodically after initiating INVOKAMET®/INVOKAMET® XR in patients with impaired renal function and in patients predisposed to hyperkalemia due to medications or other medical conditions.
- Urosepsis and Pyelonephritis: There have been postmarketing reports of serious urinary tract infections, including urosepsis and pyelonephritis, requiring hospitalization in patients receiving SGLT2 inhibitors, including canagliflozin. Treatment with SGLT2 inhibitors increases the risk for urinary tract infections. Evaluate patients for signs and symptoms and treat promptly.
Use With Medications Known to Cause Hypoglycemia
Canagliflozin can increase the risk of hypoglycemia when combined with insulin or an insulin secretagogue. A lower dose of insulin or insulin secretagogue may be required to minimize the risk of hypoglycemia when used in combination with INVOKAMET®/INVOKAMET® XR.
Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, but could occur when caloric intake is deficient, when strenuous exercise is not compensated by caloric supplementation, or when used concomitantly with other glucose-lowering agents (such as sulfonylureas or insulin) or ethanol. Elderly, debilitated, or malnourished patients, and those with adrenal or pituitary insufficiency or alcohol intoxication, are particularly susceptible to hypoglycemic effects. Hypoglycemia may be difficult to recognize in the elderly and in people who are taking beta-adrenergic blocking drugs. Monitor for a need to lower the dose of INVOKAMET®/INVOKAMET® XR to minimize the risk of hypoglycemia in these patients.
- Genital Mycotic Infections: Canagliflozin increases risk of genital mycotic infections. Patients with a history of these infections and uncircumcised males were more likely to develop these infections. Monitor and treat appropriately.
- Hypersensitivity Reactions: Hypersensitivity reactions, including angioedema and anaphylaxis, were reported with canagliflozin; these reactions generally occurred within hours to days after initiation. If reactions occur, discontinue INVOKAMET®/INVOKAMET® XR; treat and monitor until signs and symptoms resolve.
- Bone Fracture: Increased risk of bone fracture, occurring as early as 12 weeks after treatment initiation, was observed in patients using canagliflozin. Consider factors that contribute to fracture risk prior to initiating INVOKAMET®/INVOKAMET® XR.
- Vitamin B12 Levels: In clinical trials of metformin, a decrease to subnormal levels of previously normal serum vitamin B12 levels, without clinical manifestations, was observed in approximately 7% of metformin-treated patients. The decrease in vitamin B12 levels appears to be rapidly reversible with discontinuation of metformin or vitamin B12 supplementation. Measure hematologic parameters on an annual basis in patients on INVOKAMET®/INVOKAMET® XR and investigate and treat if abnormalities occur. Patients with inadequate vitamin B12 or calcium intake or absorption may be predisposed to develop subnormal vitamin B12 levels.
- Increases in Low-Density Lipoprotein (LDL-C): Dose-related increases in LDL-C can occur with canagliflozin. Monitor LDL-C and treat if appropriate after initiating INVOKAMET®/INVOKAMET® XR.
- Macrovascular Outcomes: There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with canagliflozin or metformin.
Drug Interactions With Metformin
Carbonic Anhydrase Inhibitors
Topiramate or other carbonic anhydrase inhibitors (eg, zonisamide, acetazolamide, or dichlorphenamide) frequently decrease serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis. Concomitant use of these drugs may induce metabolic acidosis. Use these drugs with caution in patients treated with metformin, as the risk of lactic acidosis may increase.
Drugs That Reduce Metformin Clearance
Drugs that are eliminated by renal tubular secretion (eg, cationic drugs such as cimetidine) may increase accumulation of metformin and risk for lactic acidosis.
Alcohol is known to potentiate the effect of metformin on lactate metabolism. Warn patients against excessive alcohol intake while receiving INVOKAMET®/INVOKAMET® XR.
Drugs Affecting Glycemic Control
Certain drugs tend to produce hyperglycemia and may lead to loss of glycemic control. These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. When such drugs are administered to a patient receiving INVOKAMET®/INVOKAMET® XR, the patient should be closely observed for loss of blood glucose control. When such drugs are withdrawn from a patient receiving INVOKAMET®/INVOKAMET® XR, the patient should be observed closely for hypoglycemia.
Drug Interactions With Canagliflozin
UGT Enzyme Inducers
Rifampin: Rifampin lowered canagliflozin exposure, which may reduce the efficacy of INVOKAMET®/INVOKAMET® XR. If an inducer of UGT enzymes must be co-administered with INVOKAMET®/INVOKAMET® XR, consider increasing the total daily dose of canagliflozin to 300 mg if patients are currently tolerating a total daily dose of 100 mg canagliflozin, have an eGFR >60 mL/min/1.73 m2, and require additional glycemic control.
Canagliflozin increased digoxin exposure. Digoxin, as a cationic drug, also has the potential to compete with metformin for common renal tubular transport systems. Monitor patients taking INVOKAMET®/INVOKAMET® XR with concomitant digoxin for a need to adjust dose of either drug.
Drug/Laboratory Test Interference
Positive Urine Glucose Test
Monitoring glycemic control with urine glucose tests is not recommended in patients taking SGLT2 inhibitors as SGLT2 inhibitors increase urinary glucose excretion and will lead to positive urine glucose test results. Use alternative methods to monitor glycemic control.
Interference With 1,5-Anhydroglucitol (1,5-AG) Assay
Monitoring glycemic control with 1,5-AG assay is not recommended as measurements of 1,5-AG are unreliable in assessing glycemic control in patients taking SGLT2 inhibitors. Use alternative methods to monitor glycemic control.
- Pregnancy: Based on animal data showing adverse renal effects, INVOKAMET®/INVOKAMET® XR is not recommended during the second and third trimesters of pregnancy. A clear association of major birth defect or miscarriage risk with metformin or canagliflozin use during pregnancy has not been determined. There are risks to the mother and fetus associated with poorly controlled diabetes in pregnancy.
- Nursing Mothers: There is no information regarding the presence of INVOKAMET®/INVOKAMET® XR or canagliflozin in human milk, the effects on the breastfed infant, or the effects on milk production. There is insufficient information on the effects of metformin on the breastfed infant and no available information on the effects on milk production. Because of the potential for serious adverse reactions in a breastfed infant, INVOKAMET®/INVOKAMET® XR is not recommended while breastfeeding.
- Females and Males of Reproductive Potential: Discuss the potential for unintended pregnancy with premenopausal women as therapy with metformin may result in ovulation in some anovulatory women.
- Pediatric Use: Safety and effectiveness of INVOKAMET®/INVOKAMET® XR in patients <18 years of age have not been established.
Geriatric Use: Because renal function abnormalities can occur after initiating canagliflozin, metformin is substantially excreted by the kidney, and aging can be associated with reduced renal function, frequently monitor renal function after initiating INVOKAMET®/INVOKAMET® XR in elderly patients and adjust dose based on renal function.
2034 patients ≥65 years and 345 patients ≥75 years were exposed to canagliflozin in 9 clinical studies. Patients ≥65 years had a higher incidence of adverse reactions related to reduced intravascular volume (eg, hypotension, postural dizziness, orthostatic hypotension, syncope, and dehydration), particularly with the 300-mg dose, compared to younger patients; more prominent increase in the incidence was seen in patients who were ≥75 years. Smaller reductions in HbA1c relative to placebo were seen in patients ≥65 years (-0.61% with canagliflozin 100 mg and -0.74% with canagliflozin 300 mg) compared to younger patients (-0.72% with canagliflozin 100 mg and -0.87% with canagliflozin 300 mg).
Controlled clinical studies of metformin did not include sufficient numbers of elderly patients to determine whether they respond differently from younger patients, although other reported clinical experience has not identified differences in responses between the elderly and younger patients. The initial and maintenance dosing of metformin should be conservative in patients with advanced age due to the potential for decreased renal function in this population. Any dose adjustment should be based on a careful assessment of renal function.
- Renal Impairment: INVOKAMET®/INVOKAMET® XR should not be used in patients with severe renal impairment (eGFR <45 mL/min/1.73 m2), with end-stage renal disease, or receiving dialysis.
- Hepatic Impairment: Metformin use in patients with hepatic impairment has been associated with some cases of lactic acidosis. INVOKAMET®/INVOKAMET® XR is not recommended in patients with hepatic impairment.
In the event of an overdose with INVOKAMET®/INVOKAMET® XR, contact the Poison Control Center. Employ the usual supportive measures (eg, remove unabsorbed material from the gastrointestinal tract, employ clinical monitoring, and institute supportive treatment) as needed.
There were no reports of overdose during the clinical development program of canagliflozin.
Overdose of metformin hydrochloride has occurred, including ingestion of amounts >50 grams. Hypoglycemia was reported in approximately 10% of cases, but no causal association with metformin hydrochloride has been established. Lactic acidosis has been reported in approximately 32% of metformin overdose cases.
- The most common (≥5%) adverse reactions with canagliflozin were female genital mycotic infections, urinary tract infections, and increased urination.
- The most common adverse reactions due to initiation of metformin are diarrhea, nausea/vomiting, flatulence, asthenia, indigestion, abdominal discomfort, and headache.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for INVOKAMET® XR.
Please see full Prescribing Information, including Boxed WARNINGS, and Medication Guide for INVOKAMET®.
Please see full Prescribing Information, including Boxed WARNING, and Medication Guide for INVOKANA®.


text:
Purchase "The Only Record"
Tom's web presence
The Peculiar Utterance of the Day [Archive]
Publications and other web appearances
Blog Archive
- Podcast: 18 years in New York City
- Podcast: Counter the Republicans
- Ron on the Met Museum's rooftop garden
- Podcast: The literary journal
- Miriam at Mitsitam Cafe in Nat. Mus. of Am. Indian...
- Photo: Rode Capital Bikeshare bike to Washington M...
- Photo: Riding a bike in Washington DC down the Mou...
- Two old pals from Urbandale Jr. High!
- Flatiron Building Seen from 150 5th Avenue, 9th Fl...
- Photo: Riding with Bill at Summer Streets!
- Podcast: Facts about NASA's Mars Science Laborator...
- Photos: Summer Streets fun!
- Photo: You got 1, 2, 3, 4, 5, 6 pockets in a table...
- Photo: Having fun on Governors Island
- ▼ August (14)
- ► 2011 (212)
- ► 2010 (232)
- ► 2009 (119)
For a more detailed overview of Tom X. Chao's work, please see his Wikipedia page that was created in October 2015.
Tom X. Chao has written, directed, produced and performed original theater pieces for over 10 years. His works include:
The Negative Energy FieldAudio: The Peculiar Utterance of the Day podcast
Can't Get Started | 2000, revived 2006
Cats Can See The Devil | 2003
Freak Out Under the Apple Tree | 2005
Callous Cad | 2009, revived 2011
The previous incarnation of this website is still available here.
Please hire Tom as an editor, indexer, researcher, or maker of bibliographies for psychology textbooks.
Ron on the Met Museum's rooftop garden
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subset: commoncrawl


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When a man-made disaster of epic proportions strikes Shanghai, China, Rios and Salem find themselves right in the middle of it all. Fortunately for you, you've got a bigger playbook of features and a new arsenal of co-op moves that either player can perform at any time, opening up fresh strategies and choices for both players. You've also got the tools you need to help the Army of Two fight and prevail with an incredibly deep, advanced weapon customization and upgrade system. Take your partner online in four explosive multiplayer modes, each focused on unique co-operative play. The Army of Two is back and better than ever!
Rated 6.5 out of 10 by Game Informer.


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Receive a FREE Original Pollo Bowl when you download the app and join
Receive a FREE Entree when you download the app and join
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Offer redeemable at participating locations only. One account per individual. One-time offer available upon install app sign-up.
Rewards and points redeemable at participating locations only.


text:
The transition to IPv6 is important not only because the 4.3 billion IPv4 addresses are running out, but also because the proliferation of Internet-connected devices is creating a new environment of information. "The Internet of Things is very much upon on us," said Vint Cerf, Google's chief Internet evangelist, at the Rocky Mountain IPv6 Summit on Thursday, April 18, in Denver.
Every device that connects to the Internet requires an IP address, and it has been predicted that by 2020 there will be 50 billion Internet-enabled devices in the world. To put that number in perspective, that equates to more than six connected devices per person, based on an expected global population of 7.6 billion people. "With the explosion of mobile devices — especially as asset intelligence and machine-to-machine embed connectivity in literally everything — unique IP addresses are becoming a scarce resource," according to Deloitte.
Thus the move to IPv6 is necessary as it provides an almost unimaginable number of IP addresses — 18 quintillion blocks of 18 quintillion possible addresses.
In a prerecorded video speech, Cerf said the proliferation of Internet connections will include automobiles. While not as high-tech as Google's self-driving car, Cerf said in the future, vehicles will report their condition and other information in order to aid maintenance. In addition, medical and scientific instruments will automatically record and report their status as well as the data they collect. "So all of you working on IPv6 are in fact working on a much larger and much more challenging scope and that is this avalanche of content and information," Cerf said.
In addition to allowing for an increasingly connected world, IPv6 will also benefit public safety communications. Latif Ladid, president of the Global IPv6 Forum, said IPv6-enabled devices, such as iPhones, provide better communication interoperability than first responders currently have. Upgrading to the new protocol will allow public safety workers to use LTE directly, enabling the sharing of not only voice communications, but also photos and videos. However, proprietary solutions and legacy systems can halt progress. "We have found that this is an important area that is going to take more decision-making than just the technology itself," Ladid said.
Although IPv6 was turned on nearly a year ago, design of the standard was done in the 1990s. "It has taken a very long time to get implementations up and running," Cerf said. Naming a couple obstacles to implementation, Cerf said currently the biggest barrier is getting Internet service providers to turn the capability on. And like all tech implementations, security is another issue – neither IPv6 nor IPv4 protect against denial of service attacks, for example. "Switching from one protocol to the other or running them both in parallel doesn't solve that problem, which simply means we have many other things to worry about," Cerf said.
But government can't afford to wait for issues to be worked out before looking at how to migrate to the new protocol. As Government Technology reported in March, the concern is that once IPv4 addresses are gone, citizens who have the new addresses won't be able to access public websites that are running on IPv4. "The challenge becomes, if you are reaching out to someone who no longer supports IPv4, you wouldn't be able to reach the person," said William Hickox, chief operating officer of the Delaware Department of Technology and Information. "It's not going to happen anytime soon, but we want to be prepared in the event that gets to be the case."
By Elaine Pittman
Source: http://www.govtech.com/policy-management/Why-the-Internet-of-Things-Needs-IPv6.html#


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Watch live video, grab images and movies plus videoconference* on your PC or Laptop
USB-Live2 has some new features compared with the USB-Live::
And some of the same great features:
Snap and print stills from whatever you're watching. Or record video clips from your camcorder or VCR to create your own high-impact presentations. With Hauppauge's SnapShot application, you can capture still video images in adjustable high-resolution modes.
The easiest way to bring video into your PC or laptop!
Don't open your PC! USB-Live2 is an external device which connects your VCR, camcorder or video camera to your PC or laptop. Plug the USB-Live into the USB port and you're ready to watch video in a resizable window, right on your PC screen!
USB-Live2 digitizes video using high quality 4:2:2 video sampling. And you can work on applications while simultaneously watching video in a resizable window.
Watch, capture or record live video from your VCR, camcorder or video camera! USB-Live connects to any S-Video or composite video source and plugs into your PC or laptop's USB port. USB-Live's video digitizer turns your analog video into digital video, and then sends 30 digital images per second over the USB (1.1 or 2.0) bus.
Spice up your multimedia presentations! Create digital movies in the Microsoft AVI file format with Hauppauge's WinTV Capture application. The included Ulead DVD MovieFactory allows you to edit and author DVD's, VideoCD's and S-VCD's.
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Desktop Publishing: With our exclusive WinTV SnapShot application, you can quickly save video images! Capture 24-bit still video still images in TIFF, JPEG, BMP in color or black/white. Also great for web design.
System Requirements


text:
Some text in the modal.
People who come into contact with hazardous chemicals at work need to know how to minimise the risk of harm to themselves, their co-workers, the general public and the environment.
The Globally Harmonised System of Classification & Labelling of Chemicals (GHS) has been developed by the United Nations and adopted by the Australian Work Health and Safety Regulations and Codes of Practice. The GHS provides a framework for standardising the methods used for classifying and communicating chemical hazards.
Running Time: 23 mins
whs harmonisation compliant


text:
By Nick Mulvenney
ROSA KHUTOR, Russia, Feb 8 (Reuters) - American Hannah Kearney arrived in Sochi as clear favourite to retain her freestyle skiing moguls crown but one mistake on Saturday means she will leave her third and final Olympics with a bronze medal.
There was no looking at positives or celebration of winning a medal of any sort from the 27-year-old from Vermont, the tears that flowed unabated told the tale of a woman who felt she had just blown four years of hard work.
The goal had been to become the first freestyle skier to win two gold medals but that all ended when, going last in the final, the American fluffed the landing off her first jump.
While there was no lack of graciousness, Kearney clearly placed the blame for her third place finish on her own shoulders rather than credit the Canadian sisters who took the gold and silver, Justine and Chloe Dufour-Lapointe.
"I feel like I let myself down," said an emotional Kearney who has dominated the event since winning gold in Vancouver four years ago.
"I wanted that gold medal and I skied for it but I made a huge mistake and you can't win at the Olympic Games when you make a mistake.
"You don't prepare for this moment, you prepare for success but life does not always go according to plan," she told reporters. "I have to treat this bronze medal as a reward for fighting but not for perfection."
Kearney has endured Olympic disappointment before.
She arrived at her first Games in 2006 with a world title under her belt and confident of at least a spot on the podium, if not a gold medal, in Turin.
The then-teenager was simply overwhelmed by the occasion, however, and stumbled after her first jump on her first run, placing 22nd in qualifying and failing to reach the final.
A serious knee injury followed but she battled back to fitness in time for Vancouver where she broke the hearts of a nation by pipping defending champion Jennifer Heil of Canada to gold on the last run in the final.
Although she will definitely not be back for the 2018 Olympics in South Korea, Kearney said she might continue competing for another World Cup season.
"Right now I would very much like to ski again," she said. "I will try my best to let it go, that will help my happiness levels.
"All of my training and all of my focus has been on this moment. Now that is over I have to re-evaluate for other goals.
"It's tough when you know your Olympic career is over and it did not end well." (Editing by Tony Jimenez)


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Are the pilots of the Fleet Air Arm in the RAF?
What types of helicopter are there? What are their roles?
Why do we need a ship borne aircraft capability?
How many helicopters are on each ship?
Does the Navy have Apache helicopters?
What is the Joint Strike Fighter?
What is the difference between an FA2 (Sea) Harrier and a GR7 Harrier?
Do Harrier aircraft operate from HMS Ocean?
What is the purpose of the Ski Jump at the front of the RN's aircraft carriers?
Question: What is the Fleet Air Arm?
Answer: The Fleet Air Arm is the Royal Navy's "Air Force". It provides air support for all naval operations.
Question: Are the pilots of the Fleet Air Arm in the RAF?
Answer: Except for exchange pilots, they are all either Royal Navy or Royal Marine Officers.
Question: What types of helicopter are there? What are their roles?
Answer: The primary roles are:
Merlin - Anti Submarine Warfare
Sea King - Troop Carrying, Airborne Surveillance and Area Control, SAR
Lynx - Anti Surface and Anti Submarine Warfare.
However, helicopters are versatile and flexible platforms and each helicopter is not restricted to the roles above and can carry out any number of subsidiary roles.
Question: Why do we need a ship borne aircraft capability?
Answer: Ship borne aircraft, with proven availability and inherent sustainability, which are able to conduct multi-role air operations from the sea, either integrated with land based air forces or independently when out of their reach, provide essential political and military options in any emerging situation. See Aircraft Carriers and Future Aircraft Carrier.
Question: How many helicopters are on each ship?
Answer: Frigates and destroyers will carry 1 or 2 helicopters, CVS and Amphibious Assault ships up to about 20 depending on requirements.
Question: Does the Navy have Apache helicopters?
Answer: Trials are currently underway, and subject to these, one Army attack squadron of Apaches will be earmarked to provide support for amphibious operations. The Royal Marines Commando Helicopter Force operate Lynx and Gazelle helicopters.
Question: What is the Joint Strike Fighter?
Answer: This aircraft, currently being developed jointly with the US is the replacement to the Harrier aircraft. It is planned to enter service in 2012 - a date that will coincide with the arrival of the first of the RNs new aircraft carriers. See Joint Strike Fighter.
Question: What is the difference between an FA2 (Sea) Harrier and a GR7 Harrier?
Answer: FA2 harriers used to be flown and operated by the Royal Navy and were designed primarily as a fighter aircraft that was also capable of ground attack as a secondary role. GR7 harriers are operated by both the RN and RAF, their primary role is ground attack and strike missions and they can operate off the decks of the RN aircraft carriers as part of Joint Force Harrier. The FA2 squadrons were disbanded in March 06 when the Royal Navy started to operate GR7/9 harriers alongside the RAF.
Question: Do Harrier aircraft operate from HMS Ocean?
Answer: In an emergency a Harrier could certainly use its vertical landing capability to land on HMS Ocean. However there are no plans to regularly operate harriers from HMS Ocean.
Question: What is the purpose of the "Ski Jump" at the front of the RN's aircraft carriers?
Answer: The ski jump is an ingenious British invention. It is used by fixed wind aircraft, such as the harrier, to take off in short distances. It helps the aircraft take off by giving it a "push" in an upward direction at the moment of launch.


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Celebrating illustration, design, cartoon and comic art of the mid-20th century.
Thursday, December 04, 2008
Jon Whitcomb's Community Christmas
The Community ads are representative of a long-held criticism of Whitcomb's work: he was prolific... and formulaic, say his detractors. But his influence on a generation of artists who specialized in the "big head" or "clinch" style of romance illustration is undeniable.
Actually, Whitcomb did have his admirers... Barbara Bradley once wrote to me, "I believe his abilities and skills are underappreciated today. He could draw! He made people look the way he wanted them to. He designed their gorgeous clothes. No one, even if they wanted to, could make eyes sparkle, lips as moist, and hair shine quite as much as did Whitcomb. His technique in watercolor and his brushwork were amazing: fluid, controlled, and varied. His portrayal of women date more than those of many other illustrators, probably because of their almost exaggerated glamour. When he painted a housewife, she wore stiletto heels, her apron ties were starched, and the flowers in her hair were fresh. But, how he could paint!"
"Whitcomb was the first magazine illustrator I really noticed. He was actually number 1 in my Hit Parade in my early high school years." Barbara concludes, "I think that he was incapable of drawing a less than beautiful girl or handsome man. He was a masterful illustrator!"
And to drive home the point, TI list member Thomas B. Sawyer (a masterful illustrator in his own right) shares this revealing anecdote:
"I remember an incident [at the Society of Illustrators] -- I think from before I was actually a member. I was at the bar with Leonard Starr, and the club was having a show of Jon Whitcomb's work. A couple of older members were beside us, making smartass remarks about Whitcomb, putting him and his illustrations down. As they wandered off, Teddy, the club's wonderful bartender, confided, as he cleared away their glasses: "I hear a lotta members make fun of Mr. Whitcomb and his work, but y'know, in the last ten years, Mr. Whitcomb ain't made less than $100,000 (in those days, a lot of money), and I don't think there's another member of this club can say that."
Tom writes, "While I do not think that money is what it was all about, I sensed, as did others, that there was a certain amount of (judgmental and financial) envy."
* My Jon Whitcomb Flickr set.
16 comments:
Leif, I'm sure that many of the rude remarks about Whitcomb were inspired by envy, just as many of the rude remarks today about Kinkade are from artists who dream of being as rich as he is. Both men were marketing geniuses, with just enough talent to get by as artists.ReplyDelete
I have to wonder, was the opposite true? Did Whitcomb ever envy other illustrators for being more talented? or did he just not care?
That's a great question, David. I think of Whitcomb as somewhat of a mysterious figure, in spite of all the examples of his work we can see and his many columns and articles from Cosmo that we can read.ReplyDelete
There are plenty of illustrators who did slick art that was, let's say, somewhat impersonal - but in my mind, that's the intriguing thing about illustration: its art with a purpose other than pure personal expression - so I have as much admiration for the pure technicians (and I would count Whitcomb among them) as I do for the more 'expressive' ones.
Perhaps Whitcomb was happy to be paid extremely well for the quality of his craftsmanship and had no urge to further explore his creative potential ...
Perhaps someone who knew him will read this and share their insight!
Leif, I didn't know Whitcomb, but ironically, a friend recently asked me who I thought the most OVER rated illustrator was during the 50's. I could think of a few under rated illustrators, but was hard pressed to come up with an over rated illustrator. I could only think of Whitcomb. I agree with David that he was a marketing genius, and I agree with Barbara Bradley that his technical skill was superb. I guess I felt his huge reputation and "pot boiler" illustrations, didn't hold up to the work of many other illustrators that didn't have nearly the notoriety, but were also excellent technically, but more creative. As I mentioned, I was hard pressed to come up with an over rated illustrator, and I'm not entirely sure he deserves my choice. My first illustration instructor was very critical of Whitcomb's work (mostly for literally painting stars for highlights in women's eyes), and perhaps that has had a greater impact on my thinking than I was aware of.ReplyDelete
Anyway, an interesting discussion, for sure.
Tom Watson
With his Cosmo columns & his gossipy articles, Jon Whitcomb was kind of a one-man glamor industry. His fellow artists at the Cooper studio didn't see much of him -- he kept a beautiful studio there, but preferred working in his home studio, in Darien Connecticut. As aloof as he was reported to be, it's interesting to imagine him privately envying, for instance, Coby Whitmore or Joe DeMers, two Cooper artists who garnered a lot more professional respect. I've never read anything by him to suggest that, but more than almost any other illustrator of his day, Whitcomb strove to present a glossy veneer to the world. I don't think refreshing candor was a part of that.ReplyDelete
Who are some of the under rated 50's artists that came to you mind?
Just curious.
Mr. Whitcomb did the illustration for one of my favorite Christmas album covers, Christmas Carols By The Lighthouse Singers. You can see it on my friend Ernie's blog. I'd love to see more Christmas album covers that were done by mid-20th century illustrators.ReplyDelete
Dan, Andy Virgil, which Leif has done an in depth feature on, was an excellent illustrator who did some women's magazine story illustrations sometime around 1960. He quickly faded, while the established illustrators, and the new innovators like Robert Weaver and Phil Hays, got the lion's share of the work and attention.ReplyDelete
Another illustrator, Robert Thom did 40 illustrations on the history of Pharmacy and 45 illustrations on the history of Medicine. They were painstakingly researched for accuracy, and superbly rendered very realistically. After the early 60's, I don't recall seeing his work, and he seemed to disappear from the public eye.
Harvey Schmidt, like Robert Weaver, was one of the leaders in annotative illustration during the 60's. But, Schmidt is never mentioned at all in articles or blogs on mid century illustration, to my knowledge. His work was unique and very painterly, leaving out unimportant detail. He and Robert Thom are both in Walt Reed's book on "The Illustrator of America".
Tom Watson
- charlie allen8:29 PM
Late, but may I join this 'food fight'? Food for thought, anyway. Are apples better than oranges? Is a steak better than a pork chop? They're all food. Preferences, yes, but not comparable....they're different. Some of us like Picasso....I prefer Degas. We can choose Rockwell, or Fawcett, or Ludekins, or Briggs, or Al Parker as our favorites. Or.....maybe Jon Whitcomb! They're all illustrators....all remarkable....but toally different in what they did. Is one better than the other? They're not comparable. No other illustrator came close to Whitcomb in rendering technique, glitz, glamour and schmaltz. Romantic fantasy? He was just the best. Too precious... sure! But, like Norman Rockwell, he probably captured the reader's popularity and name recognition more than any of the others. I'll try to scan a few examples to Leif...to further illustrate the point. We should enjoy all these talented illustrators....for what they are, and for what they accomplished. End of diatribe!ReplyDelete
I couldn't agree more, Charlie - hopefully that's what readers take away from their time here on the Today's Inspiration blog. That being said, I welcome dissenting opinions and well-reasoned criticism.ReplyDelete
Important to note in the case of Whitcomb is that Tom Sawyer was telling us how some of Whitcomb's peers regarded his work, not modern-day critics. I know, for instance, that Noel Sickles had very little good to say about Whitcomb - or any other of the 'clinch' artists - making exception ONLY for Al Parker.
In fact, Sickles felt that Whitcomb and all the others had ruined illustration - perhaps an overly curmudgeonly stance, but there you go.
And when such a criticism comes from an illustrator as universally admired as Sickles, one has to at least give his opinion some consideration, no?
Tom, I agree with you 100% that Harvey Schmidt was underrated. Part of the reason may be that he abandoned illustration to become a world famous composer (he wrote, among other things, the smash hit Broadway musical, the Fantasticks.)Still, I would love to see Leif do something on Schmidt someday.ReplyDelete
Leif, I never heard that Sickles disliked Whitcomb's work, but I did hear that Robert Fawcett was loudly uncomplimentary of Whitcomb. Whitcomb used to tell young artists that they should "look for a gimmick" to sell their art, and that they should give the sponsor "whatever they want." You can imagine how this came across to artists such as Sickles and Fawcett who believed firmly in the integrity of a picture, and were willing to give up a commission on artistic principle.
You're right, David - I went back to my favorite Sickles source material (the interview in Comics Journal #242) and it was actually interviewer, Gil Kane, who made the Whitcomb reference:ReplyDelete
"And people like Whitcomb and that whole Parker school of artist came in..."
...although GK takes pains to not paint Al Parker with the same brush:
"I hate to classify Parker with them because he was so much better.."
Sickles actually doesn't come right out and address the issue of Whitcomb specifically (that was me mis-remembering) although in the broader context of the whole interview, you do get the feeling that he is unimpressed with that school of illustration (women's romance story illustration as typified by Whitcomb).
Sickles actually describes himself as a "romantic illustrator" -- but I get the feeling he means in the same sense as the Romantic period, like Turner and Constable and so on, and is talking about a kind of adventure illustration that he and a few others were still doing, and not romance illustration of the sort Whitcomb did.
What I have called the 'New School' - Whitcomb, Parker, Whitmore, the whole Cooper studio clan - Sickles broadly defines as 'the decorators' or 'the designers' ... which is, I think, a pretty fair assessment - and although Sickles never speaks disdainfully about it, I did get the feeling that he was generally in agreement with Kane that it was not the direction he wished illustration had gone in:
Sickles says at one point, "They've gone up such a blind alley on that."
Leif, Fawcett said something almost identical to Sickles' "blind alley" point: " If we had been content... polishing simple figure studies, they might now be blinding in their degree of finish, dazzling as exercises of virtuosity, but we ourselves would be neatly trapped in that comfortable corner from which so many students fail to find the exit." Fawcett did not deny that Whitcomb had "dazzling" technique, but he though that was a closed loop (and a big snore.)ReplyDelete
Leonard Starr tells great stories about judging beauty contests with Whitcomb. He says that when illustration died, Whitcomb went down to Texas to paint life size, flattering paintings of Texas dowagers-- kind of a poor man's John Singer Sargent. Did you ever see any of those works? Apparently he made his subjects very happy.
I'm glad that you featured the work of Jon Whitcom. He was one of the Kings of Glamour among the illustrators of that almost forgotten era. I became aware of his work and all the other illustrators of that era even before I went to art school. It's been a treat to revisit their work recently.ReplyDelete
So here's another factor. Roger Reed has some reason to believe Whitcomb was gay. How might that too have contributed to the others' distancing themselves?ReplyDelete


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California State of Mind: The Legacy of Pat Brown
California State of Mind: The Legacy of Pat Brown Previous Broadcasts
KQED 9: Mon, Feb 4, 2013 -- 10:00 PM
In the turbulent 1960s, an ordinary man rose to face extraordinary challenges and powerfully shaped the future of California. Told from his granddaughter's perspective, a dynamic American dream story unfolds in this unique portrait of Governor Edmund G. "Pat" Brown, whom Tom Brokaw refers to as "the Godfather of modern California." The filmmaker provides compelling anecdotes and her perspective provides great structure for the amazing archival footage and commentary from figures ranging from Richard Nixon to Dianne Feinstein.
Repeat Broadcasts:
- KQED Life: Wed, Feb 6, 2013 -- 3:00 AM
- KQED Life: Tue, Feb 5, 2013 -- 9:00 PM
- KQED 9: Tue, Feb 5, 2013 -- 4:00 AM


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Wolf Fine Jewelers is a family owned and operated business, serving our guests in every way possible since 1972. As a full service jewelry store, we here at Wolf Fine Jewelers provide all types of jewelry repairs, custom jewelry designs, replace watch batteries and bands, along with repairing watches as well. Here at Wolf Fine Jewelers, we pride ourselves in providing the best service and offering the most popular brands on the market. It is now our mission to bring the always enjoyable visits at our stores to the internet where it can be experienced anywhere and everywhere. While our staff is always available in store to provide each guest with a memorable time, our hope is that our new and improved website will be just as easy and accommodating as coming into the store itself.
So take advantage and buy your loved one a beautiful piece of Swarovski or start them off on their very own Pandora bracelet. Better yet, treat yourself to an always stylish Michael Kors watch, or take the next step and indulge on a gorgeous Michele that will catch the attention of anybody and everybody. No matter what the occasion or reason for buying, Wolf Fine Jewelers has something for you.
At Wolf Fine Jewelers our guests always come first, and with three convenient locations, and our new revamped website, we encourage you to visit for all of your jewelry and watch needs.
Please "View our Ad" for Wolf Fine Jewelers in Garmany Magazine and browse through our Anniversary Guide.


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text: All of the pieces in the Wrendale Range feature stunning watercolour designs by Hannah Dale. Hannah founded Wrendale a number of years ago and she has built a widely successful business and brand in this time. Hannah's watercolours scream personality and look fabulous on all the pieces within the Wrendale range. Her Designs appeal to a wide audience as all of her watercolours are professional whilst still maintaining the cute look that catches the eye of the adults and children.


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Help us take on the world in the inaugural Mr. & Mrs. Smith Global Boutique Hotel Awards. From September 9th to October 9th you can vote for your favorite destination in the Mr. & Mrs. Smith collection of premium vacation properties. You can nominate a property in any of the 12 award categories which include great choices like Sexiest Bedroom in the World. As a member of the Mr & Mrs Smith handpicked boutique hotel collection, we're delighted to be in the running for a Smith Hotel Award!
Announced this November, the Smith Hotel Awards recognize the very best in service, style and personality. So, if you've enjoyed staying with us and think we deserve to bring home a trophy – and would like to have a chance to win a five-night vacation – we'd be delighted if you'd take the time to vote for us at: www.mrandmrssmith.com. Show your love for The Inn at English Meadows and Kennebunk Maine!


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Episode 4 was on last night an it was my favourite ep so far!
OMG why is there no episode on tonight? God Channel 7 is absolutely useless.
Show contentAccording to Wiki, Emily discovers her father's killer in the next episode. The following episode also relates to this.
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I have a 1950 No Design / Die Cracks on Rev. Variety Half dollar graded MS-64 by PCGS. Population of 5 in the same grade only 1 higher but this is the only one with Die Cracks Rev. Variety.
Click or cut and paste link below on browser for price and photos if interested.
http://www.ebay.com/itm/141268961760?ss ... 1555.l2649
1950 No Design / Die Cracks on Rev. Variety Half Dollar
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ST. BONAVENTURE, N.Y. — Acclaimed harpist Elizabeth Hainen will perform in recital at 3 p.m. Sunday, Jan. 22, at St. Bonaventure University's Regina A. Quick Center for the Arts in the fifth concert of the 2011-12 Friends of Good Music season.
Hainen has earned an international reputation as one of classical music's great harp ambassadors. Hailed by the Washington Post for her "unusual presence with silky transparency" and by The New York Times for her "earthy solidarity," Hainen has thrilled audiences throughout the world with programs showcasing the diversity – and virtuosity – of her modern-day instrument.
As solo harpist of the Philadelphia Orchestra since 1994, Hainen has presented numerous featured performances to captivated audiences at Philadelphia's Kimmel Center and on tour. She has been praised by the Philadelphia Inquirer for her "ability to blend and color the musical line," and "to find transparency in almost timeless atmosphere."
In high demand as a guest artist, Hainen has collaborated with such eminent conductors and musicians as Charles Dutoit, Rafael Fruehbeck de Burgos, Michael Tilson Thomas, Wolfgang Sawallisch and the Juilliard String Quartet. In addition, she has appeared as a featured soloist with the Kennedy Center Orchestra, the Orquesta Sinfonica Nacional de Colombia, the Bulgarian National Radio Orchestra, Camerata Ducale in Italy, the Chicago Civic Orchestra, the Mexico State Symphony, the Vienna Choir Boys, and in recital at Carnegie Hall.
Hainen serves on the faculties of the world-renowned Curtis Institute of Music and at Temple University.
Ludwig Brunner, interim executive director at The Quick Center, said: "We look forward to welcoming Ms. Hainen, the distinguished soloist of one of the world's leading symphony orchestras, to the St. Bonaventure campus. Our audience will get to experience the virtuosic artistry of Ms. Hainen in the intimate setting of The Quick Center's theater."
To keep winter's cold at bay in this first concert of the new year, tea and cookies will be served during intermission and after the concert, said Brunner.
Hainen's discography includes the lushly romantic "Music for Solo Harp" on the Naxos label. A review of the album published by The Harp Column praises the album and hails Hainen as "a wonderful embodiment of the 'new' Philadelphia sound and a perfect example of how the best musicians can make their instruments become a symphony orchestra, even on their own."
Hainen has also released a recording series for Lyon & Healy harps on the Egan label, and recently completed a recording of harp concerti with Rossen Milanov and the Bulgaria National Orchestra.
This performance is supported in part by the New York State Council on the Arts.
For tickets and information, call The Quick Center for the Arts at (716) 375-2494.
For this and all other performances, The Quick Center's museum galleries will open one hour before the start of the performance and remain open throughout the intermission. Regular gallery hours are 10 a.m. to 5 p.m. Monday through Friday, and noon to 4 p.m. on Saturday and Sunday. Museum admission is free and open to the public, year round.
Visit The Quick Center at www.sbu.edu/quickcenter.
About the University: Inspired for more than 150 years by the Catholic Franciscan values of individual dignity, community inclusiveness, and service, St. Bonaventure University cultivates graduates who are confident and creative communicators, collaborative leaders and team members, and innovative problem solvers who are respectful of themselves, others, and the diverse world around them
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Call it an iFreudian slip.
TNW explores why Apple iPhone's Siri assistant answers the question "what is the best smartphone ever?" with: the "Nokia Lumia 900 4G."
According to TNW, Siri relies on information results gathered up by Wolfram Alpha, which uses a bunch of data algorithms and dynamic computations, but apparently doesn't talk to the marketing folks much.
Customer satisfaction with the Lumia, which was released last month, is reportedly quite high.
But odds are that the next iPhone will restore the laurels to Cupertino.
-Tom Bemis


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There are no setup fees when you take out the loan, nor is there any charge for settling early. You may however incur charges if you fail to make your payments on time. Any late payment charges will be clearly set out in the agreement you sign with the lender and will be explained to you fully before you take out the agreement.
All loans granted subject to affordability. Proof of income will be required.
A Log Book loan is secured against your vehicle, which may be repossessed if you do not make payment.
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The Hideaway Suite
A Two room Suite, on the top floor by itself. The master bedroom has a queen size bed, TV, AC and Eco Friendly Fireplace, a beautiful hard wood floor, the walls have a Venetian plaster finish, accented by crystal chandeliers. The second room has two comfortable wing back chairs and desk (fan only). Both rooms are accented with round top windows. A private detached bathroom has an old fashioned soaking tub and shower.
$199 Weekday / $225 Weekends & Holidays
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Providence Luxury Hotel


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An amazing experience to be in a room with around 120 others for the final led Primary, we were joined by all the Intermediate people who have been getting a lay in all week, so the room was pretty jam packed. I thought I would just feel relief at having survived 6 very intense practices, but it wasn't relief I felt at the end it was a sense of satisfaction and achievement tinged with disappointment that it was over. As far as practice goes it wasn't the best one of the week, my mind was a bit in and out and I failed to get to the end of Ardha Sirsasana, coming down at 3. I did get a last assist in Paschimottanasana after the backbends. Sirsasana seemed much longer today, we speculated after that it was because there was no class following unlike the rest of the week
Sharath made the last Uth Plutihi an extra long one, or so it seemed, then he gave the usual instruction to "take rest", but before anyone could settle down a spontaneous round of applause filled the room. He thanked us and told us I think, to just keep practising.
We are all small cogs, but we make an incredibly powerful whole, it's been a wonderful experience of the Sangha coming together from London, the UK and further afield, the energy and shared joy in that room was something I didn't expect, the Ashtanga community shares something which unless you are part of it is very hard to describe to "Muggles". They can't possibly know how the abdomen cries for relief in Navasana or the arms shake in Uth Plutihi or the sheer release of lying on your back in Savasana.
Thanks to everyone who took part this week, I hope you enjoyed it as much as I did, even though I am so going to enjoy not setting the alarm tonight!
After a little Savasana we got up and joined the queue to thank Sharath and have the traditional post workshop photo taken, thanks to Mel for mine, but thanks to Hamish and Anna for organising this week and of course to Sharath.
After such a bad to start to this year, the end of the year, touch wood, will be the complete opposite, I had no intention of doing this week with Sharath but am so glad I have. It certainly hasn't put me off the journey to Mysore I am going to make in 7 weeks time. When I started this Mysore practice business with Cary two and a half years ago I had no desire to go to Mysore, but the seed was sown and events beyond my control made me think it was possible and once I realised that I wanted it circumstances seemed to arrange themselves so that with a little effort and belief on my part it's going to happen.
See you in October Mr Sharathji.


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Deductions from Pay
What deductions are allowable from a paycheck?
Find the category below that best describes the situation to determine what deductions are allowed.
NEVER allowed
The following deduction from wages is never allowed:
- Unemployment compensation …
The entire unemployment compensation premium must be paid by the business. Contact the WA State Employment Security Department for further information on unemployment compensation.
ALLOWED while employed or from final paycheck
The following deductions or withholdings are allowed when worker is still employed, on payday or when the worker has voluntarily quit or has been discharged. These deductions may reduce the employee's wage below the minimum wage in effect at the time of the deductions.
— During ongoing employment, the worker and employer must
agree to the deduction in advance and in writing.
— Deductions from a final paycheck require an oral or written agreement.
- Required state and federal taxes…
…including the worker's share of workers' compensation premiums.
- When worker agrees in advance…
…to a deduction that is to his/her benefit. Examples: personal loans, personal purchases of business's food, equipment, services, or purchase of items the business sells to the public, for the amount to bail worker out of jail, for worker health and dental insurance payments or co-payments, etc. The deduction may not cause the business to benefit financially other than reasonable interest included in the agreement.
- Medical, surgical, or hospital care or service…
...when the business pays for the worker's medical, surgical, or hospital care or service and the worker agrees to deductions from wages to repay those costs to the business. For Example: An employer and employee agree that the employer will pay hospital costs for an employee who has no insurance and the employee agrees to specific deductions from wages to repay the employer until the debt is repaid.
This is different than deductions a worker may have agreed to for insurance coverage for health, dental, hospitalization, etc. This could include an agreement between employer and employee for employer to pay hospital costs for the worker who has no insurance and the employee agrees to repay the costs to the employer.
- Court-ordered garnishments…
...including those for child support.
ALLOWED from final paycheck only when there is an oral or written agreement between the employee and employer.
The following deductions are allowed only from a worker's final paycheck. These may be applied only to incidents in the final pay period and may not be saved up from previous pay periods to be deducted from final check. They may not reduce the worker's final check below the applicable minimum wage, even if the business makes such an agreement with the worker. The business has the burden of proving that workers were informed of company policies regarding these deductions. L&I recommends that the business put all such policies in writing and obtain written acknowledgement that the worker has read and understood these policies.
- Cash shortage in the till…
...Only if the business has established policies regarding cash acceptance, and if the worker has counted money in the till before and after shift and has sole access to the till during his/her shift.
- Breakage, loss or damage of equipment…
...if it can be shown to have been caused by the worker's dishonest or willful act.
- "Bad checks" (NSF) or credit card purchases accepted by the worker…
...if the business has established check and credit card acceptance policies before the event.
- Worker theft…
...only if the business can show that the worker's act was dishonest or willful, and if the business filed a police report.
- Other agreements made orally or in writing between the worker and business at the time of termination…
...if these agreements are for the worker's personal benefit, the business may reduce the employee's final check below the applicable minimum wage. If the agreements are for the business's benefit, the final check must be paid at the applicable minimum wage for all hours worked in the final pay period.
For more detail, see these L&I WACs:
Deductions from final wages — WAC 296-126-025
Wage deductions during on-going employment — WAC 296-126-028


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Torrent Downloads » Windows - Video Apps » Cyberlink PowerDVD Ultra v8 0 1730 Multilingual Incl Keymaker
Windows - Video Apps
Cyberlink PowerDVD Ultra v8 0 1730 Multilingual Incl Keymaker
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Name:Cyberlink PowerDVD Ultra v8 0 1730 Multilingual Incl Keymaker
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What if everything your parents, teachers and preachers told you is wrong? What if being a hedonist who loves sex, drugs and rock 'n' roll is actually good for you?
This is the question explored by a recent study from the University of Hawaii called "Positive Implications for Sexual Sensation Seeking: An Exploratory Study." Another recent study found that people who take more drugs and have more sex tend to be smarter, but the idea that they might be happier as well raises all kinds of knee-jerk objections—even from me. As a parent, I have to admit, despite my philosophical belief in the connection between "liberty" and "libertine," some of the risk-taking-behavior my own kids have gotten into scares me. But does such a reaction inhibit their chances for a good life?
According to the authors of "Positive Implications," "Published research on human sexuality has been and continues to focus predominantly on negatively valenced aspects of human sexuality." As evidence, they offer an analysis of 606 research articles published over a 50-year span in academic journals like the Archives of Sexual Behavior, Journal of Sex Research, Journal of Obstetrics and Gynecology and the New England Journal of Medicine. "The majority (58%) of these articles focused on the problems associated with sexual behavior, including mental health problems, sexual dysfunction associated with sex, the dangers of sex, sexual stigma or shame, risky sexual behaviors, sexually transmitted infections, HIV and AIDS, teen pregnancy, homophobia, sexual harassment, trafficking in women, forced prostitution, bi-phobia, trans-phobia, negative attitudes and sexual violence/abuse. In contrast, a mere seven percent of articles in the content analysis investigated the delights of love, sex and intimacy."
I want to repeat that last line: "In contrast, a mere seven percent of articles in the content analysis investigated the delights of love, sex and intimacy." It makes sense for medical journals to focus on fixing problems instead of celebrating health. But seven percent?
To determine why that number is so low, I caught up with Corey Flanders, a co-author of the study, while she was attending the annual meeting of the Society for the Scientific Study of Sexuality in San Diego. She told me that the very concept of "sexual sensation seeking" (or SSS, as researchers call it) was developed in response to the AIDS crisis. "Originally, the impetus behind developing the sexual sensation seeking scale was to help identify people who were at higher risks for contracting HIV, so historically people have used the SSS scale for studying things like sexual compulsivity or willingness to engage in extra marital sexual experience, and framing that in a negative way."
But Flanders and her colleagues noticed something odd in the SSS research. Many of the studies also showed that people who have the SSS trait—and it does seem to be hard-wired, she said—were also "independent, active and curious" and rated high on related traits like openness to experience and extraversion, though these qualities were "rarely portrayed positively" in the academic literature.
This made me feel better, since it's hard to be a libertine in journalism and not feel a little bit like a freak—always mindful of the aphorism "if it bleeds, it leads." (My colleagues in the news business are always coming up with "negatively valenced" horror stories about the dangers of anything that might seem a little bit too much fun.) Remember the utterly preposterous stories about "rainbow parties," where teen girls were supposedly giving serial blow jobs to boys while wearing different color lipsticks? The more recent meme is "hookup culture," where young women are supposedly ruining their lives by having meaningless sex just like boys supposedly do. The Times ran a big story about it a few months ago, and Salon, usually a sex-positive media outlet, did the same more recently, managing to be skeptical and pro-pleasure but still, somehow, negative.
Let's face it, America is a nation of scolds. Blame it on our Puritan heritage or reach back to Calvinism and its influence on the American work ethic. But there's something in our culture that has always believed that pleasure is the work of the devil and that people who seek pleasure will end up homeless, shiftless and godless. I guarantee you that there will be comments below that rush to the old "there are higher pleasures" argument and point out with great concern that a person can get addicted to one pleasure or another, as if everyone who enjoys apple pie risks turning into a glutton. That's why we always see the term "drug abuse" and rarely the more neutral term "drug use" even when there's no abuse involved.
And, of course, it's no accident that sex, drugs and rock 'n' roll—the devil's music—have long been linked. They are things general risk-taking young people enjoy, and like so many other things associated with youth, they are tinged with danger—and, therefore, prohibited with the vast architecture of pleasure-punishing laws that have left our prisons bursting at the seams.
(Speaking of which, I still remember the first committed Christian I met—a deacon in her church—who loved to smoke pot. "I'm of a mind that God gave us all this bounty to enjoy," she explained. I was so surprised. I didn't know there were Christians who thought like that.)
Flanders approached her study, it must be said, with personal reasons to be suspicious of all the scolding. She grew up in northern Kansas, a part of the country so conservative she was taught abstinence in elementary school. She also remembers what she describes as a "terroristic stance on abortion providers." As a result, she became determined to engage in what her particular community seemed to regard as high-risk behavior—i.e., learning the scientific facts about sex. In high school, she became the go-to advisor on sexuality for all her friends. And when she got to college and took her first sexuality course, her friends back home had so many more questions that she decided to make it her career.
And so, Flanders and her colleagues launched their study to explore the positive side of bad behavior. They conducted the study by asking a total of 177 undergrads at the University of Hawaii—119 women and 58 men—a series of questions about their level of curiosity and eagerness to explore life. These included "I would describe myself as someone who actively seeks out as much info as I can in a new situation" and "I'm always out looking for new things or experiences" followed by 10 items from the standard SSS scale, statements like "I like wild uninhibited sexual encounters," "The physicality or sensation of sex is most important to me" and "I enjoy intercourse without a condom." The other questions focused on past sexual experiences and the sex positions they would like to try.
What Flanders found was:
1. SSS was, in fact, positively associated with curiosity and exploration ratings.
2. Similarly, SSS was positively associated with happiness as measured on a standard "satisfaction with life scale."
3. Less surprising, SSS ratings were very strongly associated with both experience with, and willingness to try, unusual sexual positions.
As young female academics, Flanders et al also were curious about how the supposed "hookup culture" had changed the historic tendency of men to be more adventurous than women. They found that:
1. Men still show significantly higher higher levels of SSS than women.
2. Men are more willing to try exotic sexual positions.
And there we have it; science punctures yet another anhedonic American assumption and its associated alarmist media narrative. But to be truly scientific, as Flanders was the first to point out, we should bear in mind that all studies based in sexual self-reporting come with certain caveats and cautions. For example, men might just be more willing to say they like "wild uninhibited sexual encounters," and college students might still be in the first blush of exploratory excitement before darker life consequences set in. While we wait for scientific consensus, Flanders is gathering more unexpected evidence—her latest study shows that both men and women see the people who appear in porn as both "moderately powerful and moderately positive," quite a contrast to the usual assumption that porn degrades women. "It turns out this view that porn is bad for the image of women is not true," Flanders says. "It's more multifaceted than people usually admit."
So parents of wild and horny teenagers, take hope. Get through a few stressful years and you may discover that William Blake was right after all—the road of excess really does lead to the palace of wisdom.
John H. Richardson is the author of My Father The Spy, In the Little World and The Vipers Club.
This article was originally published on Playboy for iPhone. For more exclusive content and the best articles from the latest issue of Playboy, download the app in the iTunes Store.
Photo by dk/Alamy


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Happy St. Patrick's Day everyone! Hope you all had a great day!
Well the first link party was a big success. I picked out some of my favorites to feature and I don't know how those of you with link parties pick out the features every week! There were so many great projects!
Here are a few of my favorites:
**Remember if you want to pin any of these images please go to the original source to pin them!**
Lined Long Sleeve Kimono Style Dress from Counting Crickets
Oh so pretty and I love that waistline!
P.S. I Love You Bag from Craft Couture by T.C.
I love the reverse applique and crazy quilting on this one- so cute!
Refinished Coffee Table from Lavender and Lemon Drops
This is exactly what I want in my living room- she found hers for $30- maybe I will get so lucky!
I also featured 3 other projects on my Facebook Page- go see if you were one of them!
If you were Featured- Grab a Button!
Now it is time for the 2nd edition of Scout's Sweet Sundays- let's see what you have been up to!
Just a reminder- I would love if you added my button to your sidebar or to your linky page so you can remember to come back and spread the word!!
Also, by linking up you are agreeing I can use your images for features on my blog and Facebook!


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Dalton R. Brewer has graduated from Marine Corps recruit training at Parris Island, S.C.
He is the son of Senior Master Sgt. Van Brewer (US Air Force) and Laura Garner Brewer of Tega Cay, S.C. He is the grandson of Jerry and Billie Brewer of Melbourne, Fla., and Larry and Judy Garner of Seagrove.
He attended Fort Mill High School.
Army Pvt. Ryan G. Steward has graduated from basic combat training at Fort Jackson, Columbia, S.C.
During the nine weeks of training, the soldier studied the Army mission, history, tradition and core values, physical fitness, and received instruction and practice in basic combat skills, military weapons, chemical warfare and bayonet training, drill and ceremony, marching, rifle marksmanship, armed and unarmed combat, map reading, field tactics, military courtesy, military justice system, basic first aid, foot marches, and field training exercises.
Steward is the son of Krissa Goodson of Lincolnton. He is a 2005 graduate of Lincolnton High School.
Air Force Airman Matthew R. Jeffrey graduated from basic military training at Lackland Air Force Base, San Antonio, Texas.
The airman completed an intensive, eight-week program that included training in military discipline and studies, Air Force core values, physical fitness, and basic warfare principles and skills.
Airmen who complete basic training earn four credits toward an associate in applied science degree through the Community College of the Air Force.
Jeffrey is the son of Mary Brennan of Morris Avenue, Mount Holly.
He is a 2011 graduate of East Gaston High School, Mount Holly.
Evan G. Ringle has been commissioned as a second lieutenant in the U.S. Army after successfully completing the Army ROTC (Reserve Officers' Training Corps) program and graduating with a bachelor's degree from the University of Illinois at Urbana Champaign, Ill.
The new officer will be branched to a specific corps in the Army to serve on active duty or in the National Guard or Reserve. The lieutenant will attend an officer basic course relating to his or her particular military occupational specialty/job. Afterward, the officer will complete advanced training by attending basic officer leadership courses for career progression purposes.
The ROTC curriculum prepares students with the tools, training and experiences to help cadets succeed as effective leaders in any competitive environment. Army officers serve as leaders, counselors, strategists and motivators, who lead other soldiers in all situations occurring in ever-changing environments. As trained problem-solvers, key influencers and planners, they are driven to achieve success with their team on every mission.
Ringel is the son of Steve Ringel of Denver and and Cindy Ringel of Peoria, Ill. He graduated in 2007 from Richwoods High School, Peoria, Ill.