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Editor's Note: This is the first of a series of articles reviewing the world's experience with pandemic H1N1 influenza and what we've learned in the past year. Look for further installments in the days to come.
Apr 23, 2010 (CIDRAP News) – A year's experience with the 2009 H1N1 influenza virus has underscored the endless unpredictability of flu.
The virus and the resulting illness defied expectations on many levels. It was first detected in North America, not Southeast Asia. Unlike the pathogens that caused previous pandemics, the virus was not a new subtype, but rather an H1N1 strain, making it a cousin of a seasonal flu strain that's been around for decades.
Unlike seasonal flu, though, the illness hit children and nonelderly adults much more than people over 65. It was relatively mild for most people, unlike the 1918 flu or the devastating disease associated with H5N1 avian flu, which had heavily shaped pandemic preparations. But it killed far more children and young people than seasonal flu typically does, with the vast majority of deaths involving people younger than 60.
The pandemic also brought the first hint that obesity is a risk factor for severe flu. And it reinforced an old and somewhat underappreciated lesson: that pregnant women who contract flu also can get seriously ill and even die.
In one of the biggest surprises, the pandemic virus made seasonal viruses do a vanishing act this past winter, at least in the United States. Although type B and H3N2 viruses circulated to some degree in certain parts of the world, such as Asia, they failed to show up or appeared in only tiny numbers in the US.
This week, a year after the pandemic virus first burst into the headlines, several experts contacted by CIDRAP News reflected on the past year and the lessons it has taught about the virus and the illness. Future stories will look at treatment issues, the H1N1 vaccine, the vaccination program, and other public health responses.
New, but not new
A big surprise to many—and a source of terminological confusion—was that the H1N1 virus is not a new subtype. As an H1N1 virus, it is the same subtype as the virus that caused the 1918 pandemic and whose descendants have circulated in humans ever since, except for one 20-year interruption.
As virologist Vincent Racaniello, PhD, of Columbia University describes it, the H1N1 virus of 1918 went into both people and pigs at the time and evolved on mostly separate tracks in the two different hosts. In humans the subtype circulated until 1957, when it was replaced by the H2N2 virus, which triggered the pandemic of 1957-58. H1N1 then vanished from humans until 1977, when it mysteriously reappeared, probably as the result of a lab accident. It then continued to evolve as one of three seasonal flu strains, with H3N2 and type B.
Meanwhile, the H1N1 in pigs continued to circulate, but evolved much more slowly than its human counterpart, according to Racaniello, who authors "Virology Blog." Because pigs, as food animals, don't live very long, their viruses don't face very much selection pressure, he explained. "So that virus that went into them in 1918 didn't change very much. It did reaasort with a variety of human and avian viruses, but the key proteins, the HA and NA, are direct descendants and haven't changed very much. To me that's the most amazing thing, that pigs have almost been like a freezer for this virus."
While the H1N1 in pigs changed little, human strains of H1N1 changed a lot, under pressure from the immune system of their long-lived hosts, Racaniello said. By 2009, the human and pig versions were so different that when the swine version jumped into humans, many people had little protection against it.
The fact that seasonal H1N1 and the pandemic H1N1 are the same subtype obscures how different they are, Racaniello said. "Subtypes are kind of artificial definitions," he commented. "The H1N1 pandemic virus is as different from the previous seasonal H1N1 as it is from an H3N2. So the fact that we're calling it H1N1 doesn't really mean anything. We should get used to the idea that a pandemic could be caused by the same subtype [as a seasonal virus]."
Dr. Daniel B. Jernigan of the Influenza Division at the Centers for Disease Control and Prevention (CDC) expressed a similar view. "[The pandemic H1N1] is not a new subtype. But the distance from the nearest neighbor causing routine human disease is pretty far, so in that sense it's not unexpected that you'd have significant numbers of people who have not had exposure to anything like this," he said.
As it turned out, of course, those who had some protection against the pandemic virus were older people, who benefited from their encounters with H1N1 viruses before 1957. Those who had some exposure in the 1930s, 1940s, and to some degree the 1950s probably have some immunity, said Jernigan.
Geographic expectations
Another surprise to many, given that the last two pandemics and H5N1 avian flu had their roots in Southeast Asia, was that the pandemic virus was discovered in North America. The first known cases of the 2009 H1N1 occurred in Mexico, with cases popping up in the United States shortly afterward.
But Racaniello said it's not known where the virus really emerged. "We had the first reports in North America, in Mexico and the US. That doesn't mean it went from pigs to people there; it doesn't mean it originated in those areas." But even if it did, he added, "I don't think it's surprising, because we have lots of pigs in North America, and [pigs are] where this virus came from."
The virus's real birthplace may never be pinpointed, because its ancestors are missing from the surveillance records for at least 10 years, he said. "The parents haven't been detected for a long time. I don't know if we're going to figure that out. The moment may have passed."
Wave pattern
In the United States, the 2009 virus first spread widely in late April and May, slowed but hung around through midsummer, heated up again in late summer as children returned to school, and peaked in late October and early November. Then it waned fairly quickly, and a feared third wave never materialized in the winter.
In this pattern of waves the pandemic differed sharply from seasonal flu but bore some resemblance to past pandemics, especially that of 1957. "If you look at pandemic epi curves, what we saw in 1957 was very similar to what we saw this year, in the shape of the curve and the time it appeared," said Jernigan. He said no significant winter wave was noticed in 1957-58, but mortality data later suggested that one did occur.
The absence of a winter wave of cases this time around may be explained by a shrinking number of susceptible people. With the combination of immunity in older people, the virus's presence through the summer, and a major wave of cases in the fall, "What we may have done was burn through a significant amount of the population, so there weren't enough susceptibles left to have a third wave," said Jernigan.
In addition, by winter a growing number of people had gained immunity through vaccination, further limiting the number of easy targets for the virus, noted William Schaffner, MD, chair of the Department of Preventive Medicine at the Vanderbilt University School of Medicine and a board member of the Infectious Diseases Society of America. The CDC's current estimate of the number of people vaccinated is between 72 million and 81 million.
Impact on the population
The true impact of the pandemic on the population won't be known for some time to come, given that pandemic viruses tend to dominate flu seasons for several years and that it takes 2 to 3 years to develop accurate flu mortality data for a given season. The number of cases can only be estimated, because costly confirmatory testing was sharply reduced within weeks of the outbreak's start.
But it's safe to say that the public generally regards the pandemic as mild, or at least milder than news reports led people to expect. The perception is based on the fact that for most people the illness resembled seasonal flu and also that the number of cases dropped steeply after the fall peak. In addition, the CDC's latest estimate of deaths in the pandemic is 12,270, well below the oft-cited CDC estimate of 36,000 in a typical flu season—though the two estimates are based on different methods.
But the perception of the pandemic as mild overlooks the reality that cases and deaths have targeted mainly children and young adults, in sharp contrast to seasonal flu. About 90% of the deaths in a typical flu season are in elderly people, whereas most of the pandemic deaths have been in younger adults and children.
"Normally severe flu strikes children under 4 and people over 65 and spares healthy people from 5 to 65. What we see is it did not spare older children and younger adults," said Andrew Pavia, MD, chief of pediatric infectious diseases at the University of Utah Health Sciences Center and chair of the pandemic flu task force for the Infectious Diseases Society of America (IDSA).
The CDC estimates that 35 million cases have occurred in adults aged 18 to 64, 19 million in children through age 17, and just 6 million in those older than 64. The proportions are similar for hospital cases, estimated at a total 270,000. And out of an estimated 12,270 deaths, there were 9,420 in the younger adult group, 1,580 in the elderly, and 1,270 in children.
The H1N1 burden on younger people was also underscored by a recent report in BMC Infectious Diseases with data from the early months of the pandemic in 11 countries: It showed that more than 75% of cases occurred in people age 30 and under, with the highest incidence in those 10 to 19. Only 3% of cases were in people 65 and older.
"What we had in terms of overall severity doesn't fit easily into a headline," said Pavia. "We had a disease that caused largely moderate illness in most people," but there was a risk of severe disease for young children, pregnant women, people with underlying diseases. About 278 children died of confirmed H1N1, far more than the previous record of about 88 in a flu season, he added.
In view of the disease burden on younger people, a team of researchers led by Cecile Viboud of the National Institutes of Health recently tried to refine our understanding of the pandemic's impact by estimating the total years of life lost. They estimated the number of deaths to be between 7,500 and 44,100, with the lower number based on deaths officially attributed to pneumonia and influenza and the higher number representing all-cause deaths, including those from diseases associated with flu but not necessarily reported as such.
Their main finding was that, in life-years lost, the pandemic was at least as severe as a nasty regular flu season and possibly worse than the pandemic of 1968-69.
Health system stressed
As for the pandemic's impact on the healthcare system, the general verdict is that there were signs of stress, but the system was not overwhelmed.
"Our clinical capacities were stretched but not broken by this pandemic," said Schaffner. He credits the built-in protection enjoyed by older people for sparing the system. Without that, he said, "We would've been in much hotter soup just taking care of patients. Because in this country we've pared down our excess medical capacity, just because it's so expensive."
Pavia said hospitals were not too hard hit overall, but some emergency departments, particularly pediatric emergency units, were "extremely stressed." Some had to set up satellite units in their parking lots during the peak period. Pediatric emergency departments have probably done more disaster training than other departments because of the heavy load of respiratory illnesses they face each winter, he commented.
Intensive care units (ICUs) also were put to the test, Pavia said. One colleague reported that his hospital's ICU at one point ran short on dialysis machines, not on ventilators, which are often cited as likely to be scarce in a pandemic. "In planning we didn't think about dialysis machines," he said.
But from the reports he has heard, ICUs had more problems with staffing than with equipment, Pavia said. Workers became exhausted from caring for young adults who required long periods of intensive care. "It may be that the greatest vulnerability in our intensive care capacity is personnel, the ability to sustain effort over a long period of time," he commented.
The clinical picture
The clinical illness caused by the novel H1N1 virus was generally similar to seasonal flu, experts say. But the intense scrutiny of the pandemic brought some new aspects to light and underlined previous lessons.
"Clinically I'd have to say the illness is fairly similar to what had been reported before," said Kathleen M. Neuzil, MD, MPH, an associate professor of medicine in the division of allergy and infectious diseases at the University of Washington in Seattle and chair of the influenza working group for the CDC's Advisory Committee on Immunization Practices (ACIP).
"I think we have to be careful in interpreting some of [the findings], because this would have to be the most studied virus, if not in history, then for a very long time," she said. "There was a lot more testing and a lot more capturing of different types of disease."
For example, there have been reports that quite a few H1N1 patients had no fever, seeming to suggest that this could be peculiar to the pandemic virus. But in the past, said Neuzil, the CDC definition of influenza-like illness included fever, so afebrile flu cases would not have been counted. "The pandemic made us look a little harder at the illness; it made us look more broadly," she said.
In fact, Jernigan said the pandemic and seasonal viruses probably differ little in this respect. "There were some reports that up to a third or even half of individuals didn't have fever, which is not so different from seasonal flu, but we don't have a lot of good data."
Another tentative finding is that gastrointestinal (GI) symptoms are more common in H1N1 cases than with seasonal flu, which, if true, would have implications for transmission.
"The GI symptoms do appear to be somewhat more prominent than with seasonal," said Pavia. "We've seen that in H5N1 in Southeast Asia. It's interesting in terms of clinical presentation, but it also raises the possibility that some patients will be able to transmit infection by shedding virus in their stool."
Jernigan said the CDC has observed a higher-than-expected rate of GI problems in H1N1 patients, but he's not sure if it's real. "I don't know that we have enough data to say that this virus truly causes more GI illness," he said. "It's not unheard of for you to get more GI problems when you get flu."
A feature that has turned out to be less common than expected in H1N1 cases is bacterial coinfections, Jernigan reported. "We saw them, but they were not as prominent as we expected, probably due to a lot of antibiotic use and vaccination against strep pneumo," he said.
Streptococcus pneumoniae and Staphylococcus aureus are the typical causes of pneumonia secondary to flu, he noted. "We've been vaccinating against strep pneumo for the past 10 years or so, and we may be seeing a benefit during the pandemic of that vaccination program."
Community acquired methicillin-resistant S aureus (MRSA) has emerged in recent years and makes a "bad combination" with flu, Jernigan added. "We saw that, but we didn't see it in the amount we thought we would—maybe because people are using more of the right antibiotics."
In terms of transmissibility, the experts agreed that the H1N1 virus seems to differ little from seasonal flu. However, Schaffner said it appears that children can shed the virus considerably longer than is the case with seasonal flu—for a week or a week and a half after recovery. In seasonal flu cases, it gets much harder to recover virus by 3 or 4 days after the onset of symptoms, he said.
Obesity emerges as risk factor
One thing that clinicians noticed about adult flu patients with serious H1N1 infections is that many were obese. "People were struck by the number of morbidly obese patients in their units," said Pavia.
It's an association that has not been prospectively studied, he said, but added, "I think it's real. I think it's probably a moderate-strength risk factor, and we were not in a position to notice it before."
"That is something we did find that is unique," Jernigan affirmed. "It came up early because of the kinds of individuals that were getting sick. They were otherwise health individuals, 30s to middle-aged, that were in ICUs and needed long-term respiratory support. It does look like obesity, especially morbid obesity, is a perhaps a significant risk factor."
A recent study by a CDC team using data from the early months of the pandemic showed that patients who were morbidly obese were nearly five times as likely to be hospitalized as were normal-weight patients. Their risk of death was also higher, but the difference was less dramatic.
The reason for the finding is unclear, but it may be simply that obesity is more common now than it once was, Jernigan commented. He also cited a recent study in which obese mice seemed to have poorer immunologic memory compared with lean mice.
Schaffner commented that the identification of obesity as a risk factor for complications "comes as no surprise to clinicians. They know that taking care of large people with lung infections is much more difficult than people who are lean," because of physical factors.
Danger for pregnant women
Another risk factor, albeit not a new one, that the pandemic highlighted was pregnancy. "One lesson was that flu is a dangerous disease for pregnant women. We knew it but it wasn't that prominent in our consciousness," said Pavia.
Reports from the first months of the pandemic suggested that pregnant women accounted for about 5% of H1N1 deaths, though they make up only about 1% of the US population. This finding echoed, though on a much smaller scale, what happened in the 1918 pandemic, which took a heavy toll on pregnant women.
Jernigan said there were indications early in the pandemic that obstetricians and gynecologists "weren't really thinking about flu as something that might harm their patients." The pandemic experience has raised their awareness of the risk, in his view. And messages about the risk to pregnant women pushed H1N1 vaccination rates for pregnant women well above the typical levels for seasonal flu shots, he added.
Other risk factors for serious H1N1 cases include asthma and, particularly in children, neurologic disorders, both of which are also seen in seasonal flu, Jernigan reported.
The pandemic brought a number of reports from various countries that racial and ethnic minorities seemed more susceptible to severe H1N1 illness. Jernigan said that pattern holds for both pandemic and seasonal flu: Majority and minority groups have about the same risk of contracting flu, but minorities are more likely to get seriously sick. The reasons are various and include access to care and vaccination, care-seeking behavior, and reluctance to be vaccinated.
Among patients who got severely sick, some showed signs of suffering a "cytokine storm," an overly intense immune response that floods the bloodstream with pro-inflammatory chemicals and causes the lungs to fill up with fluid, according to Pavia. The phenomenon is believed to have been a common feature in fatal cases in the 1918 pandemic.
"There were certainly patients who appeared to have the kind of catastrophic shock-like illness that's been blamed on cytokine storm," he said. "We don't as of today have a lot of evidence that those severe multi-organ system dysfunction patients had cytokine storm; it just resembles that and fits with the hypothesis."
Other lessons learned
One of the important lessons of the pandemic was the value of early antiviral treatment for patients with severe illness or at risk for severe illness, according to Pavia. He said it was hard to get this point across to clinicians. (A later story will look at the use of antivirals in the pandemic.)
Another lesson of the past year, in Pavia's mind, is the need for networks of clinical investigators prepared to swing into action when an outbreak starts.
"We did a pretty good job of getting clinical information quickly—the CDC, NIH, and other investigators stepped up to the plate, but we don't have an organized system to do that," he said. Clinical investigations "were cobbled together on the fly." They worked reasonably well, but systems set up in advance would be more effective, he added.
A more general lesson, according to Neuzil, is the need to avoid "tunnel vision" in pandemic preparedness, as exemplified by focusing heavily on the H5N1 threat. "One lesson for preparedness is for us to think very broadly and just look at multiple different scenarios," she said.
That was done to some extent, particularly regarding increased surveillance and the stockpiling and distribution of antivirals, Neuzil added.
Outlook for next season
One abiding mystery of the pandemic, experts agree, is why the 2009 H1N1 virus pushed the seasonal flu strains almost completely off the stage this past winter. That makes the question of what will happen next winter all the more interesting.
The disappearance of the seasonal strains "remains a fascinating mystery," said Pavia. "Everything we'd say would be pure speculation. We expected that H3N2 and B would've resurfaced this year, and it's hard to explain their absence based on cross-immunity related to [2009] H1N1." Some level of cross-immunity between the novel virus and the seasonal H1N1 probably accounts for the latter's exit, he added.
The experts expect the pandemic virus will be around again come winter, but they offer a range of views on which other flu viruses will be competing with it. The approaching flu season in the Southern Hemisphere will offer the first clues.
Racaniello expects that the pandemic strain will follow the pattern of past pandemics and dominate flu seasons for at least 10 years. "It'll probably be just H1N1 and B viruses; the H3N2 and the previous seasonal H1N1 will be gone," he said.
Pavia agreed that the pandemic H1N1, with or without drift mutations, will circulate next winter. "And I'd guess B will be back. But what will happen to H3N2 or H1N1 Brisbane [seasonal H1N1], I have no idea."
Schaffner said he, too, expects the 2009 H1N1 virus to be back. But because of the likely level of population immunity, he said, "My expectation is it'll be a minority player in 2010-11. I'm sticking my neck out here."
And Jernigan commented, "If we had to guess, I think we'd say seasonal H1N1 is not likely to hang around." He expects the pandemic strain to be the dominant player and to become the new seasonal H1N1. As for H3N2, which displaced H2N2 back in 1968, "I don't know exactly what will happen this fall, but I would guess that the H3N2 would actually persist. This is a guess."
See also:
CDC's latest estimates of cases, hospitalizations, and deaths
CDC's Flu View surveillance update
Mar 23 CIDRAP News story "Study: In life-years lost, H1N1 pandemic had sizable impact"


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Selena Gomez's Social Media Purge Explained
Is Selena Gomez turning over a new leaf for the better?
Earlier this week, the singer-actress raised eyebrows when she deleted photos with Kendall and Kylie Jenner at Coachella and unfollowed everyone on Instagram, including on-and-off-again boyfriend Justin Bieber and once BFF Taylor Swift. It seems that there may be an explanation for her behavior.
Both E! Online and TMZ cite sources that while at Coachella, Selena had an epiphany and realized that she needed to remove negative influences from her life. Selena reportedly attended parties filled with hard partygoers and came to the conclusion that she needed to stay away from that lifestyle. Instead, Selena is said to be reevaluating her friendships and focusing on more positive people and experiences, such as working on her music and going to church more.
This comes after what has seemingly been a stressful year for Selena so far. It was reported in January that Selena spent some time in rehab and appeared to have taken a break from Justin Bieber, who has been battling problems of his own. But the two have been caught together a few times, including at SXSW in Austin and more recently at Coachella.
In addition to her purge, Selena has also cryptically posted the lyrics to Mary J. Blige's 'Work in Progress' on Instagram, which includes lyrics about self-improvement such as "I got every material thing I could ever need / I got the love from my fans that adore me / And I'm grateful / But my love for myself is lacking a little bit / I can admit that I'm working on me."
Whatever Selena's reasons are for her recent social media activity, we do wish her luck in whatever goals she has planned for herself.


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NIAID offers many resources to support your research, including reagents, model organisms, and tissue samples, to name just a few. Use the filters under Filter Search Results to narrow your search, or simply enter specific search terms in the search field.
Center for International Blood and Marrow Transplantation Research (CIBMTR) Database
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This mod doesn't really do anything directly useful; it was just an itch I wanted scratched.
A few gamers may remember Bungie's amazing "Myth: The Fallen Lords" back in the mid-90s, which set the bar for small unit fantasy tactical combat (and a wonderful backstory/voiceover "feel" which imho has yet to be matched in any game since).
Anyway, one of its well-done (albeit depressing) features was that whenever one of your units died, rather than either glossing over it or dwelling on it, a neutral voiceover voice would just say "Casualty." And in a big battle where you were sweating bullets and your troops were dying in large numbers, having this horribly neutral voice chanting "Casualty. Casualties. Casualty." was both maddening and yet energizing. It added something.
Anyway, for no good reason I decided I wanted that in WoW, so I coded up this little mod. It's horribly incomplete (for one thing, it triggers when pets die, which I should fix, and may trigger on other things) but it did what I wanted, so I thought I'd share it. If I have time and anyone in the universe wants it to do more, I may add more flexible announcements, integration with SCT so you get a message zipping up the screen with the name of who died, etc. But right now, with its basic "casualty" message, it does what I wanted.
Note: What you have for a sound sample is me and a microphone, since the actual sound samples from Myth are not free for public distribution, so feel free to go through the trouble of replacing them if you wish.


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Relationships with
Photo Credit: Cody Rhodes' picture is courtesy of Wikipedia. Photographic illustrations of Cody Rhodes are copyright © by their respective holders. The images are published with permission or as allowed by the copyright law's fair use or quotation provisions. If any copyright holder objects to an image being included, please notify us and it will be removed immediately.
Disclaimer: This information about Cody Rhodes is derived from astrological interpretation of Cody Rhodes' date, time, and place of birth.


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CARLSBAD, Calif., Nov. 1, 2012 /PRNewswire/ -- Life Technologies Corporation (NASDAQ: LIFE) has received a Letter of No Objection from the U.S. Department of Agriculture -- Food Safety and Inspection Service (USDA-FSIS) for its RapidFinder™ STEC (Shiga-toxin producing Escherichia coli) Detection system. Developed in collaboration with the USDA, the solution provides meat producers a new, validated solution that accurately detects the presence of multiple strains of E. coli in raw beef in just 10 hours.
The Letter of No Objection supports the test's effectiveness and allows companies to comply with the USDA's regulation standards. The RapidFinder system's quick turnaround time to achieve accurate results reduces the standard six-day process established by the USDA Microbiology Laboratory Guidebook (MLG). While the MLG method provides confident results and isolation of E. coli, the traditional process is time consuming, labor intensive and requires too many reagents, all of which drive up cost.
"The more strains of E. coli that meat producers can quickly and accurately analyze, the more likely they can ensure that beef is safe for public consumption," said Nir Nimrodi, Vice President and General Manager of Food Safety and Animal Health at Life Technologies. "The success of RapidFinder STEC is partially attributed to the large pool of leading customers who served as beta testers and with whom we also collaborated on this product. The USDA's Letter of No Objection further validates our solution's ability to satisfy the unique safety and business requirements within the meat industry."
RapidFinder™ significantly reduces the rate of false negative and false positive results, hurdles that can delay safe beef products from arriving to market. The system has also been designed to integrate seamlessly within existing testing programs, resulting in improved efficiency, productivity and cost savings.
Life Technologies collaborated with the USDA to develop a test to detect the presence of E. coli O157:H7, and later expanded the project to include the "Big 6" non-O157 strains (O26, O45, O103, O111, O121 and O145), which cause about 70 percent of non-O157 infection.
The validated system is capable of clearing negative beef samples (375 grams), and identifying presumptive positives in the same sample run with an additional hour of testing. Its sensitivity provides greater confidence in the results since the solution can detect as little as 1 to 5 colony-forming units of pathogenic STEC in a single sample.
Life Technologies collaborated with the USDA to develop and validate RapidFinder™ and utilized Life's core competencies in DNA sample preparation, real-time PCR assay formats design, DNA sequencing and data interpretation.
RapidFinder™ STEC is for Testing of Food and Environmental Samples.
About Life Technologies
Life Technologies Corporation (NASDAQ: LIFE) is a global biotechnology company with customers in more than 160 countries using its innovative solutions to solve some of today's most difficult scientific challenges. Quality and innovation are accessible to every lab with its reliable and easy-to-use solutions spanning the biological spectrum with more than 50,000 products for agricultural biotechnology, translational research, molecular medicine and diagnostics, stem cell-based therapies, forensics, food safety and animal health. Its systems, reagents and consumables represent some of the most cited brands in scientific research including: Ion Torrent™, Applied Biosystems®, Invitrogen™, GIBCO®, Ambion®, Molecular Probes®, Novex®, and TaqMan®. Life Technologies employs approximately 10,400 people and upholds its ongoing commitment to innovation with more than 4,000 patents and exclusive licenses. LIFE had sales of $3.7 billion in 2011. Visit us at our website: http://www.lifetechnologies.com.
Life Technologies' Safe Harbor Statement
This press release includes forward-looking statements about Life Technologies' anticipated results that involve risks and uncertainties. Some of the information contained in this press release, including, but not limited to, statements as to industry trends and Life Technologies' plans, objectives, expectations and strategy for its business, contains forward-looking statements that are subject to risks and uncertainties that could cause actual results or events to differ materially from those expressed or implied by such forward-looking statements. Any statements that are not statements of historical fact are forward-looking statements. When used, the words "believe," "plan," "intend," "anticipate," "target," "estimate," "expect" and the like, and/or future tense or conditional constructions ("will," "may," "could," "should," etc.), or similar expressions, identify certain of these forward-looking statements. Important factors which could cause actual results to differ materially from those in the forward-looking statements are detailed in filings made by Life Technologies with the Securities and Exchange Commission. Life Technologies undertakes no obligation to update or revise any such forward-looking statements to reflect subsequent events or circumstances.
(Logo: http://photos.prnewswire.com/prnh/20110216/MM49339LOGO)
Life Technologies Contact
Patty Zamora
760-476-7818 (work)
760-277-1669 (mobile)
|SOURCE Life Technologies Corporation
Copyright©2012 PR Newswire.
All rights reserved


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Unrau, Abram Abram (1856-1930)
Abram Abram Unrau: a Mennonite leader in the Chortitza settlement of South Russia; was born 14 June 1856, the oldest of the six children of Abram Unrau (30 April 1813, Kronsweide, Chortitza, South Russia – 28 October 1890) and Agatha (Heese) Unrau (17 November 1823, Chortitza Mennonite Settlement, South Russia – 17 December 1883). He married Gertrude Thiessen (16 May 1856 – 15 September 1902, New York, Ignatyevo, South Russia), daughter of Peter Heinrich Thiessen (1826–1906) and Helena (Kaetler) Thiessen (1823–1900), in August 1876. Abram and Gertrude had 16 children: Peter, Abram, Agatha, Helena, Gertrude, Johann, Wilhelm, Anna (d. young), Maria, Katarina, Cornelius, and Magaretha; four others died in infancy. His second wife was Mrs. Maria Hildebrand, widow of Isaac Hildebrand.
Abram was educated at the Chortitza Zentralschule. After their marriage, Abram and Gertrude lived in Chortitza until 1878 and then moved to an estate at Roppov-Gauchur, where they lived until 1889. In 1888 the mother colony of Chortitza had purchased land from Count lgnatiev and established the Ignatyevka Mennonite settlement. In 1889 Abram Unrau moved from his Hochfeld estate to New York in the Ignatyevka Mennonite settlement. Here he became an excellent farmer who made the best possible use of his land. The Unraus at first lived in the Count's former residence, which also served many others as a dwelling place until they had built their own homes. Later, this residence also housed the three classes of the newly established Girls School until a new school was built in 1907. The Central School was built two years earlier in 1905.
Abram was ordained as a minister on 8 June 1890, and as elder on 16 June 1900 in New York.
For twenty years Elder Unrau was widower. Around 1920-1922 he married Maria, the widow of minister Isaac Hildebrand, and moved from New York to Ekaterinovka (No. 1), Ignatyevka Mennonite settlement. When his health began to fail, his daughter Katharina went to take care of him. At that time many people from New York were immigrating to America. When the emigrants gathered in Konstantinovka, Elder Unrau, lying in his wagon, had himself driven there so he could take leave of them.
Abram was a wise leader and was well read. He died 30 August 1930, at New York, South Russia, where he was interred in the local cemetery.
GRANDMA (The Genealogical Registry and Database of Mennonite Ancestry) Database, 5.00 ed. Fresno, CA: California Mennonite Historical Society, 2006: #199044.
|David Paetkau
|Richard D. Thiessen
|Date Published
|May 2007
Cite This Article
MLA style
Paetkau, David and Richard D. Thiessen. "Unrau, Abram Abram (1856-1930)." Global Anabaptist Mennonite Encyclopedia Online. May 2007. Web. 3 Jul 2020. https://gameo.org/index.php?title=Unrau,_Abram_Abram_(1856-1930)&oldid=132464.
APA style
Paetkau, David and Richard D. Thiessen. (May 2007). Unrau, Abram Abram (1856-1930). Global Anabaptist Mennonite Encyclopedia Online. Retrieved 3 July 2020, from https://gameo.org/index.php?title=Unrau,_Abram_Abram_(1856-1930)&oldid=132464.
Adapted by permission of Herald Press, Harrisonburg, Virginia, from Mennonite Encyclopedia, Vol. 4, p. 783. All rights reserved.
©1996-2020 by the Global Anabaptist Mennonite Encyclopedia Online. All rights reserved.


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Don't give up your day job just yet.
The Maya peoples never disappeared, neither at the time of the Classic period decline nor with the arrival of the Spanish conquistadores and the subsequent Spanish colonization of the Americas. Today, the Maya and their descendants form sizable populations throughout the Maya area and maintain a distinctive set of traditions and beliefs that are the result of the merger of pre-Columbian and post-Conquest ideas and cultures. Millions of people speak Mayan languages today; the Rabinal Achí, a play written in the Achi language, was declared a Masterpiece of the Oral and Intangible Heritage of Humanity by UNESCO in 2005.
Their empire is gone, but the people are alive and well. I believe that the human sacrifice thing was primarily an Aztec custom, rather than Mayan.
So according to certain "scholars" the world is going to end tomorrow. Or, I guess more accurately, in about 6 ½ hours (give or take a few micro-seconds). But the six some odd hour's thing is just a guess since the Mayans did not actually say when on the 21st the world was actually going to end.
Now don't get wrong here, I am not thumbing my nose at the Mayans or the scholars who "deciphered" the calendar that suddenly stops on the 21st of the 12th 2012. I will have to admit that I don't care enough to spend too much time searching the net for additional references to the day the world ends. I probably should though just to be on the safe side.
I don't want to wake tomorrow morning and waste my time being superior and doing the "See! I told you…
View original post 736 more words


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The 2012 cold-stun season for sea turtles in New England broke records. National Aquarium's Animal Rescue team helped out our colleagues at the New England Aquarium by admitting 13 sea turtles for rehabilitation last December. We transported several turtles to Florida for long-term rehab and release in January, and several more for release to Florida in April.
We currently have four remaining turtles in our rehab center: two Kemp's Ridleys (Duckie and Bender), a green (Willard), and a loggerhead (Rooney). We are very excited to announce that three of the four turtles are ready for release!
Any release is a cause for celebration, but this release is extra special, as we'll be celebrating the release of our 100th animal! Actually, Duckie, Bender and Willard will represent our 100, 101 and 102 animals released! Since 1991, National Aquarium Animal Rescue has been responding to stranded marine mammals and sea turtles found along the Delmarva Peninsula (which encompasses Delaware, Maryland and Virginia).
In the last twenty years, our team has cared, rescued, treated and released a variety of species to their natural habitats, including: seals; sea turtles; rough-toothed dolphins; a harbor porpoise; a pygmy sperm whale; and a manatee. Each of these animals has an incredible story, and there is no better triumph than returning a healthy animal to the wild! You can read some of these stories on our website.
We're excited to announce that our 100th release will be open to the public. Find out more details below:
National Aquarium 100th Rescue Animal Release
Saturday, June 22
4:00 pm EST
Point Lookout State Park in Scotland, MD
The release will occur at the Swimming Beach
Normal park entrance fees will apply
Join our National Aquarium Animal Rescue team as we release three turtles: two Kemp's Ridley's (Duckie and Bender) and a green (Willard).
Staff from the National Marine Life Center will also be on-site to release four rehabilitated sea turtles!
Sea turtles utilize the Chesapeake Bay as a source of food during the summer months. The two Kemp's ridley's and the green sea turtle that we will release this Saturday will likely remain within the Bay for the rest of the summer before migrating south in the fall. The loggerhead will remain in rehabilitation for long-term treatment of a chronic medical issue and will be released at a later date.
We hope you can join us to say farewell to Duckie, Bender, and Willard!
If you're not able to join us on the beach, be sure to follow me on Twitter for live updates, and leave your well-wishes for the trio in the comments below.


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Cook the Book: Beet Seed Cake
You might assume that this Beet Seed Cake would be made with well, beet seeds. Before you start running to the garden center in search of ingredients you should probably know this cake is made with beets and seeds, not beet seeds. Sounds weird, right?
I thought so too but in the intro of Tender: A Cook and His Vegetable Patch, Nigel Slater likens it to another genius root vegetable-based dessert, the carrot cake. Though not quite as sugary as carrots, beets do possess a sweetness and distinct earthiness that comes through in this cake. When making the batter, the beets are grated and blended in, dyeing the batter an eye-popping magenta.
Testing out this recipe at home I was expecting a bright pink loaf to emerge from the oven, but somehow during the baking, the batter returned to a less exciting, tan cakey hue. But the little shreds of bright beets remained and the orange flower water and poppy seed glaze prettied it up.
Adding a selection of crunchy, nutty, and very good-for-you seeds (flax, sunflower, and pumpkin) are also incorporated into the cake giving it an unexpected textural excitement as well as a decidedly healthy element, especially when you factor in the beets. All of these vitamin-rich additions make this coffeecake-like Beet Seed Cake a great excuse to eat cake for breakfast.
As always with our Cook the Book feature, we have five (5) copies of Tender: A Cook and His Vegetable Patch to give away this week.
Reprinted with permission from Tender: A Cook and His Vegetable Patch by Nigel Slater. Copyright © 2009, 2010. Published by Ten Speed Press, a division of Random House, Inc. Available wherever books are sold. All Rights Reserved.
- Yield:8 to 10
- Active time: 20 minutes
- Total time:1 hour 10 minutes
- 1 3/4 cups (225g) self-rising flour
- 1/2 teaspoon baking soda
- 1 scant teaspoon baking powder
- 1/2 teaspoon ground cinnamon
- 3/4 cup (180ml) sunflower or Brazil nut oil
- 1 cup (225g) light muscovado sugar
- 3 eggs, separated
- 5 ounces raw beets
- Juice of half a lemon
- 1/2 cup golden raisins or raisins
- 1/2 cup mixed seeds (sunflower, pumpkin, flax)
- For the icing:
- 1/2 cup confectioners' sugar
- Lemon juice or orange blossom water
- Poppy seeds
Preheat the oven to 350°F (180°C). Lightly butter a rectangular loaf pan (8 x 4 inches [20 x 9cm], measured across the bottom, and 23/4 inches [7cm] deep), then line the bottom with parchment paper.
Sift together the flour, baking soda, baking powder, and cinnamon. Beat the oil and sugar in a stand mixer until well blended, then mix in the egg yolks one at a time. Grate the beets coarsely and fold into the mixture, then add the lemon juice, golden raisins, and the seeds.
Fold the flour, baking soda, and baking powder into the beet mixture and combine at low speed.
In a separate clean bowl, beat the egg whites until light and almost stiff. Fold gently but thoroughly into the beet mixture, using a large metal spoon (a wooden one will knock the air out). Pour the mixture into the prepared pan and bake for fifty to fifty-five minutes, covering the top with a piece of aluminum foil after thirty minutes. Test with a skewer for doneness. The cake should be moist inside but not sticky. Let the cake rest for a good twenty minutes before turning it out of its pan onto a wire cooling rack.
To make the icing: Sift the confectioners' sugar into a bowl and add enough lemon juice or orange blossom water to achieve a consistency where the icing will run over the top of the cake and drizzle slowly down the sides (about three teaspoonfuls), stirring to remove any lumps. Drizzle it over the cake and scatter with poppy seeds. Rest for a bit to set before eating.
All products linked here have been independently selected by our editors. We may earn a commission on purchases, as described in our affiliate policy.


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For many who recall the United States' Cold War-fueled boycott of Russia's 1980 Olympics — and the Russians' retaliatory shunning of the 1984 games in Los Angeles — the 2014 Winter Olympics have the potential to reconcile three-decade-old wounds.
The Games, taking place at the Russian resort town of Sochi, mark the first time an American Olympic team will compete on the soil of the former Soviet rival.
Even if the athletes themselves don't recognize the significance, politicians, scholars and many fans will.
U.S. & World
Proxy battles
A lot has changed since the old days, when international sports were seen as a proxy for the battle between American-style capitalism and Soviet-style Communism. Russia and America remain fierce adversaries in the post-Cold War era, but the roles, experts say, have shifted.
Russia, a traditional Winter Olympics superpower, has fared relatively poorly recently, and views the Sochi Games as a way to reassert itself — similar to its diplomatic flexing with the United States over Syria and Edward Snowden, and its passing over antigay laws, which sparked an international outcry.
America, meanwhile, aims to maintain its dominance on the global stage. Over the past decade, Team USA has become a Winter Olympics force — in Vancouver four years ago, its record 37 medals made it the overall winner for the first time since 1932. Germany was second in Vancouver with 30 total medals, followed by Canada's 26.
Russia finished sixth, with 15, widely considered an embarrassment. That showing fueled expectations for the Russians, as 2014 hosts, to redeem themselves on a grand scale.
"The idea that the politics still have meaning, the sense that whose political and economic system and infrastructure is better will play out in international sports, is still as real for the Russians as it is for the United States," said Philip D'Agati, who researches the relationship between the Olympics and politics at Northeastern University.
Hockey rivalry
Nowhere will that be more apparent than in the Olympic hockey rink. There aren't many team sports at the Winter Games, and hockey has historically represented the wider battle for worldwide bragging rights.
The Soviet Union reigned over men's ice hockey for decades, winning gold medals in seven of the eight Winter Olympics from 1956 to 1988. But in the two decades since the republic's breakup, Russia has won just one silver and one bronze (and shared in the 1992 Unified Team gold). It hasn't played in a gold-medal game since 2002.
In Sochi, as the hosts, the Russians are expected to win men's hockey gold, with Canada, Sweden and the United States expected to challenge them for the title.
There are plenty of individual events where the two countries will vie for medals, including figure skating. But the bulk of the Russians' medal haul will likely come, as it has in the past, in less publicized competitions, like cross-country skiing and the biathlon, experts say.
There will also be opportunities in several new events: the ski half-pipe, women's ski jumping, the biathlon mixed relay, a figure skating team event and the luge team relay.
Sochi's challenges
Because Sochi is a subtropical resort, there are also concerns that the weather will cooperate. The Russians have been stockpiling snow just in case.
At the same time, they are scrambling to finish construction of the Sochi complex, from roads to event spaces.
There are also concerns over Russian President Vladimir Putin's crackdown on freedom of expression, and the country's new laws banning "gay propaganda."
Russian officials said the laws are supposed to protect children and will not infringe on athletes or fans. The International Olympic Committee makes a point of not interfering with local laws, and has reminded athletes of rules against making political statements at the games. A few Americans, including skier Bode Miller and figure skater Ashley Wagner, have spoken out against the laws in pre-Olympics media events. In the days leading up to the Games, protestors have called on Olympic sponsors such as McDonald's and Coca-Cola to take a stand against the laws.
Cold War reverberations
Some called for another American boycott, but the idea has not gained much political traction. With the hindsight of 30 years, many historians regard the United States' decision not to attend the 1980 Summer Games in Moscow as a mistake.
The move, by President Jimmy Carter, was in response to the Soviet Union's invasion of Afghanistan. Several other countries, including Canada, Japan and West Germany, joined the U.S. But the Moscow Games otherwise went on without a hitch, and many consider the event a relative success.
Four years later, the Soviets retaliated with a boycott of the 1984 Games in Los Angeles.
The successive snubs represented a low point of the Olympic movement, which considers itself above politics.
In many ways, that's more true today than at any point of the Olympic history. The Games are now a huge, global television event, and a commercial leviathan. Their economic impact has diminished the role of nations' political conflicts, said Robert Edelman, a history professor at the University of California at San Diego and an expert on the sporting relationship between the United States and Russia.
"It's not freighted the way the Olympics once were," Edelman said.
This time around, in Sochi, the pressure comes more from a country's expectations of itself. The Russians will set the tone with the Opening Ceremony, which will likely reflect the former Soviet republic's long history of dominance in international winter competition.
And then the athletes will try to put that history behind them.


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- Talk/music time: about 5 hours
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IDescriptif Technique
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Letting .com Domain Expire
on Saturday, January 26, 2013
/ Comments: (0)
Just a quick post to note that I'm letting my .com domain expire. If you still somehow care about having this blog in your feedreader, you should adjust accordingly. :-) P.S. Yeah, it's because I'm a grad student now and thus really broke.
On living, loving, learning, and fucking with the materials I've got at hand.
This work by anewparadox.blogspot.com is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.
Some of the content on this blog may be unsuitable for those under 18. If you're underage, try Scarleteen.com for info on sex.
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NASHVILLE, Tenn. – Tennessee State men's basketball point guard Patrick Miller was nominated for the 2014 Allstate National Association of Basketball Coaches (NABC) Good Works Teams® on Tuesday. The award recognizes a select group of college basketball student-athletes who have made significant contributions to the greater good of their communities through volunteerism and civic service.
In its second year, the Allstate NABC and Women's Basketball Coaches Association (WBCA) Good Works Teams® honor players at all levels of college basketball who represent the sport's finest in the areas of leadership and charitable achievements amongst their peers. The student-athletes nominated for this prestigious award embody the true spirit of teamwork and giving back.
"Allstate is proud to recognize these two outstanding groups of men and women whose commitment to service and volunteerism demonstrate that 'good works' extend beyond the basketball court," said Pam Hollander, senior director of marketing for Allstate Insurance Company and a member of the 2014 NABC and WBCA Good Works Teams® selection panels. "Each of the nominees serves as a role model and inspiration to future generations seeking ways to give back, and another reason to celebrate the good happening in our communities."
While jump shots and rebounds earn recognition on the hardwood, the Allstate NABC and WBCA Good Works Teams® help tell the stories of good taking place off the court that often go unnoticed. It is those players who demonstrate the exceptional ability to balance academics with athletics while donating their limited free time to serving others who have been nominated by their respective colleges and universities for this prestigious honor.
The 2014 nominees uphold impressive service resumes detailing unique and inspiring stories of servitude. From volunteering with sick and underprivileged children to lobbying state legislature for new laws that could help save lives, this exceptional group of young men and women demonstrate the positive impact student-athletes can have on and off the court.
From the 118 NABC nominees and 84 WBCA nominees submitted by sports information directors across the nation on behalf of their schools, special voting panels will select two 10-member teams comprised of five student-athletes from the NCAA® Division I level and five student-athletes from NCAA® Divisions II, III and the NAIA.
Since 2008, Allstate has partnered with the American Football Coaches Association (AFCA) as sponsor of the Allstate AFCA Good Works Team®, which shines a spotlight on the positive, off-the-field impact college football student-athletes have on their communities. Through an arrangement with the AFCA, NABC and WBCA, Allstate is able to expand the Good Works Team® to also recognize college basketball student-athletes at all levels who donate their time and effort to make a difference off the court.
More information about the Allstate NABC Good Works Team® and the Allstate WBCA Good Works Team® is available at www.nabc.org and www.wbca.org.
Courtesy National Association of Basketball Coaches


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Meet the newest recruit in the Adult Swim Games army: Major Mayhem. He's got an itchy trigger finger, some scratchy stubble, and a fondness for shooting dudes in the face. Run and gun your way through gorgeous 3D environments as you embark on a mission to rescue your kidnapped girlfriend from the Forces of Evil. Guns, grenades and an assortment of other tools of destruction are at your disposal, and you'll need every last one of 'em. So what are you waiting for, Major Mayhem? The future of the Free World -- and your love life -- hangs in the balance.
• 45 levels of non-stop action
• 4 game modes
• 100 achievements
• 150 mini mission objectives
• 5 power ups
• Battle your way past hordes of enemies in three picturesque environments: Tropics, Metropolis and Desert
• 20 unique weapons in your arsenal to deal out MAJOR MAYHEM, like: Automatic Shotgun, Minigun, Quadzooka (like a Bazooka only more massive-er!) , And more!
• 42 costumes and hats to make your Major's fashion conscience which dealing massive devastation!
• Save the world, and your girlfriend
- Add Unlimited Clothes.
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- If the generator is working, it will display human verification to avoid Spam or Robot.
- and If the generator not showing human verification, so reload the current page and start from first step again.
- After all is done, go back in the generator page and you'll see a status.
- Let's open the game in your devices and look, your resources is there and ready to use.
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Today 9459 User has Generated GRABYOURCODECOM BASEBALLNINE Gems and Coins.
From 9459 User Today, we Record 9370 User Success Generated GRABYOURCODECOM BASEBALLNINE Gems and Coins
From 9459 User Today, we Record 147 User Failed Generated GRABYOURCODECOM BASEBALLNINE Gems and Coins.


text:
The ancient Greek philosophers have urged countless generations to "Know Thyself". Now there's a website that can tell you (and others) who you are with one mouse click.
Spokeo.com, a split personality website which marries online 'white pages' with an information gathering search engine, allows subscribers to search for individuals by name, location, ect. and relays information about marital status, household income, political affiliation, and other vital tidbits.
This site was a topic of discussion at our FPLD Genealogy Club meeting last night. Our speaker Robin Seidenberg reminded us that our information isn't really private in this digital age. (BTW: Read Jennifer Holik-Urban's review of last night's meeting. It's fantastic!)
According to their website, Spokeo is "a people search engine that organizes vast quantities of white-pages listings, social information, and other people-related data from a large variety of public sources. Our mission is to help people find and connect with others, more easily than ever."
The really interesting aspect of this website, apart from the cute name and accurate mapping tools, is the epic failure of the information available.
According to Spokeo, I'm married, and live with my parents, three siblings, grandmother, and several cats in my parent's home in Michigan.
Our house appraised at over one million dollars, I'm a Catholic, a Republican, and I run a home-based business. My hobbies are cooking and traveling. My astrological sign is Aries, and I enjoy reading books about fashion.
WOW! I'M MARRIED! REALLY? WHEN DID THAT HAPPEN? (Shouldn't I remember something like that? I know some people would like to forget their marriage, but am I one of them?)
AND GRANDMA'S ALIVE! NO WAY! (Dude, she died a decade ago! But to be fair, we still get her catalogs and mail.)
I'll admit my parents just had their kitchen remodeled, but I've dropped off their mortgage checks at the bank, and there's NO WAY their home is worth one million dollars.Political and religious privacy aside, I don't run a home based business.
Did they get anything right? Yes. My parents have a cat, I am an Aries, and I enjoy cooking and traveling.
And I could have found out more about myself, like my education level, my economic health, or my wealth level if I purchased a one-year subscription to the website for the ultra low price of $2.95 a month.
So, go to Spokeo.com, get to know yourself, and comment on your findings in the comment/reply section below, and let me know what you think.
In the meantime, if you find my husband on Spokeo, tell him to come home to my flat, because he doesn't need to drive to my parents place. I want to start a family, and I need him to help me hang up the new curtains I bought and empty the trash before garbage day. Oh, and tell him we're having my deceased grandma over for the weekend, so we'll need to run a few errands before then.
See you at the Library!


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Honor the Heroes of the Game, Preserve Its History, Promote Its Values & Celebrate Excellence Everywhere
"A man has to figure out what has to be done and how to do it. You have to be able to spin out of a block, recognize a play immediately and then react accordingly. I figure I'm as strong as anyone else; so getting the job done becomes a matter of pride and determination."
(Texas Christian)...6'5'', 260...Robert Lewis Lilly ... Consensus All-American at Texas Christian ... Cowboys' first-ever draft choice (1961), first Hall of Famer (1980) ... Foundation of great Dallas defensive units ... Had unusual speed, strength, intelligence, recovery ability ... All-NFL/NFC eight years ... Named to 11 Pro Bowls ... Played in five NFL/NFC title games, two Super Bowls ... Missed just one game in 14 years ... Born July 26, 1939, in Olney, Texas.
Bob Lilly was a two-time All-South West Conference pick and a consensus All-America choice at Texas Christian before the Dallas Cowboys' selected him as their first-ever draft choice in 1961.
For the next 14 seasons, his play on defense was so outstanding that he became popularly known as "Mr. Cowboy." Bob starred as a defensive end in 1961 but then moved to a defensive tackle spot in his third season with even more sensational results. As a tackle, Lilly was a first-team All-NFL choice every year from 1964 through 1969, then again in 1971, and 1972. The only years he missed first-team honors was his final two seasons in the league and in 1970 when he was a second-team choice.
Equally effective as both a pass rusher and a rushing defender, Lilly continually battled double-team and even triple-team opposition but he rarely was delayed in his pursuit of the ball carrier. Quick, agile and coordinated, he even scored four touchdowns in his career. One came on a 17-yard interception return in 1964 while the other three came on fumble recoveries. Altogether, he returned 18 fumbles for 109 yards.
Extremely durable, Bob played in 196 consecutive regular-season games. His only career "miss" came in the 1973 championship game with Minnesota, when a leg injury put him on the bench. Post-season play became a way of life for the 6-5, 260-pound Olney, Texas, native. The Cowboys played in seven NFL/NFC title contests in an eight-year period from 1966 through 1973 and also in Super Bowls V and VI. Bob also was selected to play in 11 Pro Bowls. He is the first player who spent his entire career with the Cowboys to be elected to the Pro Football Hall of Fame.
Championship Games
1966 NFL – Green Bay Packers 34, Dallas Cowboys 27
Lilly started at right defensive tackle and blocked one extra point.
1967 NFL – Green Bay Packers 21, Dallas Cowboys 17
Lilly started at right defensive tackle. He had three tackles, one pass defensed and one sack for a nine yard loss.
1970 NFC – Dallas Cowboys 17, San Francisco 49ers 10
Lilly started at right defensive tackle. He finished with 3 tackles and 2 assists.
1971 NFC – Dallas Cowboys 14, San Francisco 49ers 3
Lilly started at right defensive tackle. He had two tackles and one sack for a loss of six.
1972 NFC – Washington Redskins 26, Dallas Cowboys 3
Lilly started at right defensive tackle. He had four tackles and seven assists.
1973 NFC – Minnesota Vikings 27, Dallas Cowboys 10
Did not play.
Super Bowls
Super Bowl V – Baltimore Colts 16, Dallas Cowboys 13
Lilly started at right defensive tackle. He had four tackles.
Super Bowl VI – Dallas Cowboys 24, Miami Dolphins 3
Lilly started at right defensive tackle. He had three tackles, three assists, and one sack for a loss of 29 yards.
All-NFL: 1964 (AP, UPI, NEA, NY), 1965 (AP, UPI, NEA, NY), 1966 (AP, UPI, NEA, WA, NY), 1967 (AP, UPI, NEA, NY), 1968 (AP, UP, NEA, NY, PW, PFWA), 1969 (AP, NEA, PW, NY), 1971 (AP, PFWA, NEA, PW), 1972 (PW)
All-NFL Second Team: 1969 (UPI), 1970 (PFWA, NEA), 1972 (AP, PFWA, NEA), 1977 (NEA)
All-Pro: 1968 (PFWA), 1969 (HF, PFWA, NEA)
All-Conference: 1964 (SN), 1965 (SN), 1966 (SN), 1967 (SN), 1968 (SN), 1969 (SN), 1971 (AP, UPI, SN, PW), 1972 (AP, UPI, SN)
All-Conference Second Team: 1970 (UPI), 1973 (UPI)
(11) – 1963, 1965, 1966, 1967, 1968, 1969, 1970, 1971, 1972, 1973*, 1974*
* Did not play
(at time of his retirement following 1974 season)
• [Tied for 1st] Most Touchdowns, Opponents' Fumble Recovery, Career - 3
• [3rd] Most Consecutive Games Played, Career – 196
(Cowboys' Records held by Lilly at the time of his retirement following the 1974 season)
• [1st] Most Consecutive Games Played, Career – 196
Team Statistical Championships
Sack Titles: 1961, 1962, 1963
• 75th Anniversary All-Time Team
• 1960's All-Decade Team
• 1970's All-Decade Team
• All-Time NFL Team
• AFL-NFL 1960-1984 All-Star Team
Full Name: Robert Lewis Lilly
Birthdate: July 26, 1939
Birthplace: Olney, Texas
High School: Throckmorton (TX); Pendleton (OR)
Elected to Pro Football Hall of Fame: January 19, 1980
Enshrined into Pro Football Hall of Fame: August 2, 1980
Presenter: Tom Landry, Dallas Cowboys head coach
Other Members of Class of 1980: Herb Adderley, Deacon Jones, Jim Otto
Pro Career: 14 Seasons, 196 games
Drafted: 1st round (13th player overall) in 1961 by Dallas Cowboys. Also drafted in 1st round of 1961 AFL Draft by Dallas Texans
Uniform Number: 74


text:
Are you ready to start your business?
These checklists can help you find license stipulations, tax information, and other requirements for which you must comply to formally establish your business.
Business Registration Checklist
This checklist has been created by the Missouri Business Portal, which is a part of the University of Missouri Small Business Development Center.
Licenses and Registration Checklist
This checklist was created by the Missouri Small Business Development Centers, which is maintained by the University of Missouri Extension Service.
Small Business Planner
Explore the section titled "Start Your Business" for the checklist of information for which you must be aware before you start your own business. This site was created by the U.S. Small Business Administration.
Avvo, the legal assistance, company has a small business assistance website. Information on the site includes startup procedures to set up a business, how to operate a business, business documents, and other information on small businesses.


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5 Amazing Glow-in-the-Dark Halloween Activities
Do your kids love things that glow in the dark?
Want to astonish your neighbors and trick-or-treaters?
How about serving some spooky shimmering refreshments at your next Halloween party or haunted house?
With a black light and just a few ingredients that make things glow, you can have the creepiest crypt on the block.
In this article, you'll learn how to produce my five favorite glow-in-the-dark science projects, perfect for making a ghoulish impression this Halloween.
Why Should I Make Glowing Concoctions?
Halloween, more than any other time of year, is the season to explore nighttime frights, conduct spooky experiments and investigate unexplained phenomena. Halloween is dark and disguised and mysterious. It's the perfect backdrop for things that glow and gush after the lights go out.
The five glow-in-the-dark projects below are a fun way for you and your kids to get into the spirit of this eerie, ominous time of year and add your own bit of creepy cheer to parties or your own family adventure on a chilling October afternoon.
How to Create Black Light Halloween Messages With Your Kids
Do your kids like to send secret messages to their friends?
Want a cool way to explore science while playing in the dark?
Your family will be wowed by this fun and easy project that teaches the properties of fluorescent light.
In this article, I'll show your budding scientists how to design their own secret messages and reveal them when the lights go out.
Why Create Black Light Secret Images?
Black light secret images incorporate a whole lot of things that are awesome to kids (and maybe to you big kids, too!).
They appear to float in mid-air. They glow in the dark.
And not only do your kids get to create messages themselves, but they also control when the secret codes are revealed with a special, magical black light.
This is a fun and simple activity for a Halloween party, sleepover or anytime.
Use the image viewers as Halloween lanterns to add a spooky element to trick-or-treating and an extra way for you to see the kids in the dark. (Be sure to bring along a flashlight too.)


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Peer-Reviewed Publications
Found 596 resultsTitle
Healthcare Barriers and Utilization Among Adolescents and Young Adults Accessing Services for Homeless and Runaway Youth." J Community Health. 2017;42(3):437-443."
Improving Primary Care Provider Practices in Youth Concussion Management." Clin Pediatr (Phila). 2017:9922817709555."
An Initial Application of a Biopsychosocial Framework to Predict Posttraumatic Stress Following Pediatric Injury." Health Psychol. 2017."
Intentional Abuse of Loperamide: Exposure Trends Reported to US Poison Control Centers, 2011-2016." Clin Toxicol (Phila). 2017;13."
Learning to Predict Driver Behavior from Observation. Stanford University: Association for the Advancement of Artificial Intelligence; 2017.
Longitudinal Study of Driver Licensing Rates Among Adolescents and Young Adults With Autism Spectrum Disorder." Autism. 2017:1362361317699586."
Motor Vehicle Crash Risk Among Adolescents and Young Adults With Attention-Deficit/Hyperactivity Disorder." JAMA Pediatr. 2017."
Parent Coping Support Interventions During Acute Pediatric Hospitalizations: A Meta-Analysis." Pediatrics. 2017."
Pathophysiology and Treatment of Memory Dysfunction After Traumatic Brain Injury." Curr Neurol Neurosci Rep. 2017;17(7):52."
Perceived support at work after critical incidents and its relation to psychological distress: a survey among prehospital providers." Emerg Med J. 2017."
Perspectives of hospital emergency department staff on trauma-informed care for injured children: An Australian and New Zealand analysis." J Paediatr Child Health. 2017;53(9):862-869."
The Psychosocial Needs of Adolescent Males Following Interpersonal Assault." Journal of Adolescent Health. 2017."
Rear-facing versus forward-facing child restraints: an updated assessment." Injury Prevention. 2017;Online First, November 25, 2017."
Rising Cost of Antidotes in the US: Cost Comparison from 2010 to 2015." Clin Toxicol (Phila). 2017;55(5):360-363."
Road safety perspectives among employees of a multinational corporation in urban India: local context for global injury prevention." Int J Inj Contr Saf Promot. 2017:1-8."
Tackling Bullying: Grounds for Encouragement and Sustained Focus." Pediatrics. 2017;139(6)."
Ten-Year Trends in Bullying and Related Attitudes Among 4th- to 12th-Graders." Pediatrics. 2017;139(6)."
Trauma-informed Care for Children in the Ambulance: International Survey Among Pre-hospital Providers." European Journal of Psychotraumatology. 2017;8(1)."
Trauma-informed care for children in the ambulance: international survey among pre-hospital providers." Eur J Psychotraumatol. 2017;8(1):1273587."
Usability, Acceptability, and Impact of a Pediatric Teledermatology Mobile Health Application." Telemed J E Health. 2017."
Video Analysis of Factors Associated With Response Time to Physiologic Monitor Alarms in a Children's Hospital." JAMA Pediatr. 2017;171(6):524-531."
What Do Clinicians Caring for Children Need to Know about Pediatric Medical Traumatic Stress and the Ethics of Trauma-Informed Approaches?" AMA J Ethics. 2017;19(8):793-801."
Youth-Adult Connectedness: A Key Protective Factor for Adolescent Health." Am J Prev Med. 2017;52(3 Suppl 3):S275-S278."
Adolescent Cellphone Use While Driving: An Overview of the Literature and Promising Future Directions for Prevention." Media and Communication. 2016;4(3)."
After-Hours Call Center Triage of Pediatric Head Injury: Outcomes After a Concussion Initiative." Pediatr Emerg Care. 2016;32(3):149-53."


text:
do (one's) bidding(redirected from did our bidding)
do (one's) bidding
To do what someone else wants or has requested, to the point of servitude. I hate how my mother always wants me to do her bidding—I refuse to do what she wants any longer! I can always get Tom to do my bidding, which is great when I'm faced with something I don't want to do!
See also: bidding
do someone's bidding
to do what is requested. The servant grumbled but did his employer's bidding. Am I expected to do your bidding whenever you ask?
See also: bidding


text:
This new forum is designed as a networking forum where companies can post job openings or opportunities directed at the lacrosse community across the country.
If you want to hire a lacrosse person, please feel free to post your job opening, job location, how one could apply for the job, and any other important details.
Special thanks to sdsulax for suggesting this new forum!
Welcome to the new Employment Opportunities forum!Do you need to hire someone? Please list your job openings or opportunities here.
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- Location: Atlanta, GA
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text:
The best day turns for the worst when a guy loses his...
All Is Lost53583171
- by Colton7912, Carter987321 & Sadowski
- Rating:
- Published: 24 Nov 2014
- Updated: 16 Dec 2014
- Status: In Progress
Its a normal day. Just a day with the bros, Gavin, Joe, and Jerron just working on our fort when we see something in the distance. We decide to investigate and thats when we figure out... Its a zombie!
Join MovellasFind out what all the buzz is about. Join now to start sharing your creativity and passion
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text: The guys at Speedhunters have been obsessed with all things Porsche this month. To continue the fun, they got their hands on some awesome footage of Stuttgart's racing efforts from 1976. Of course, they weren't content to leave well enough alone, so they've given the film a modern spin. The result may put off some purists, but you can't deny the ageless appeal of a fire-breathing beast like the Porsche 935 screaming around the track at the 24 Hours of LeMans. Check out Speedhunters' video here.


text:
Wait! That's WWE '13's music!
THQ will probably be showing off the teaser for their next sports entertainment extravaganza at E3 in two weeks.
But the trailer trickled out onto the internet a bit early. The clip spotlights current WWE Heavyweight Champion CM Punk as the game's centerpiece, a move that pleases me greatly. Punk's been a great performer in the ring and on the mic, yet found himself stifled by WWE management's favoritism and way-too-safe story arcs. It got to the point where he made a big stink about it.
The reel also makes reference to Punk's classic meta-commentary promo where he talks about the state of creativity in WWE. Hopefully, the game will keep the brash edge of CM Punk's character alive in the game.
The trailer also shows an in-game recreation of last year's ring-collapse spot with the Big Show and Mark Henry.
Hopefully, you won't have to play as those two big lunks to trigger that catastrophic event. Undertaker and Kane should be enough, right? We'll get a chance to find out when WWE '13 hits in November.


text:
call upon(redirected from call upon us)
call upon (someone)
1. To choose, request, obligate, order, or demand someone to do something. Yesterday the president called upon world leaders everywhere to promote open and fair trade between countries. He was called upon to give testimony in court.
2. To visit someone. I went to the East Coast last week to call upon my aunt.
call upon
1. To order or require someone to do something: I call upon you to tell the truth.
2. To make a demand or a series of demands on something: Social institutions are often called upon to assist the poor.
3. To visit someone: I called upon an old friend when I was in New York.
4. To make use of some resource; draw on something: I knew the task would call upon my every resource.


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In the words of They Might be Giants, "time is marching on and time is still marching on…"
This time of year time feels a little bit sped up with all the gatherings and events and parties and to-do lists and travel plans and whoa! Wait a minute! All of a sudden we're freaking out with all that's on our mind/calendar/list/plate! You know the feeling? Well chill because here are 8 ways to gain more time without actual time travel. Seriously.
1. Take a deep breath. It really is the first step in calming yourself down when your mind is swirling about. Perhaps you're saying, "But I don't have time to take a deep breath gosh darnit!" And I'm saying really, you do. And if you do, you might actually feel time expand a tiny bit. And if you take a few deep breaths, you might feel it expand even more. So pause what you're doing. Whatever it is. And for a minute or two, just concentrate on breathing. You'll oxygenate your body and mind and give yourself a chance to approach things more calmly which will in fact feel like time expanding. No matter where you are, pause and take a deep breath or a few. Really intentional, big, deep breaths.
2. Get out of your head. Rather than letting all the things you have to do swirl about in your head uncontrollably and continuously, make a list. The list frees your brain from overwhelm and puts all the things you need to do in front of you where you can see them, approach them and deal with them. One. By. One. So you can slowly get them all done. Put your list on paper or on your phone or wherever it will be most helpful. The beauty of the paper list vs. the electronic list is that you get the satisfaction of crossing things out with a very animated, intentional swipe of your pen. And once they're crossed off you can see just how much you've done. And when you've got the list in full action, you'll see that many of the things that swirl so furiously in your head, might only take minutes to accomplish and don't need to occupy so much mental energy.
3. Cross something off. I don't mean cross it off because it's done. I mean cross it off as in don't do it. Surely there's one thing on your list that doesn't really NEED to get done. Maybe it's an event that you really aren't OBLIGATED to attend. Or maybe it's an activity that you realize you don't really need to do. Whatever it is, on almost everyone's list, there is something that can be deleted. Or at least delayed until another time when you have more time.
4. Combine efforts. There are different ways you can approach this combination of efforts. Try to schedule things so that all your activities fall back to back on the same day – making for a busy day yes but also leaving other days of the week open for you to feel more spacious. If you're meeting someone for coffee one morning, segue immediately into the next without leaving the space. If you're volunteering at school or elsewhere in the community, schedule it so that another errand or task is done immediately afterward. This not only blocks your time nicely but also gives definitive end times to each activity. You can also block things by time of day, scheduling all your extra activities in a certain time frame each morning leaving the rest of the day free for your own personal or work related efforts. On the days that are to be for your projects only, put it on the calendar with the same importance as the meetings. Write it down in order to protect that time from the intrusion of other things that might be presented.
5. Schedule less. If you're feeling this overwhelm often, perhaps you ought to think about trying to do less. If it's making you stressed or anxious, then maybe it really is too much. Consider eliminating things not just for one time but for the longer term. Maybe you're on too many committees or in too many groups. Whatever it is, they will be there when you're ready but if it's too much, you're not serving anyone by overextending yourself.
6. Delegate. Surely you don't need to do everything yourself. Got a friend, co-worker or family member who might pick up some of the slack? Ask your partner to take on one of your tasks. Or your kids to chip in a little more with things. Or your parents or friends to babysit so you can get something done. Try doing things co-operatively such as child care or toy shopping or post office or whatever is on your list. No point in all of us doing all of it. Share, trade, barter, bargain. Whatever you can do to make things feel more efficient and fun.
7. Get more sleep. Sure it seems funny to think of sleeping more as giving you more time but seriously, when you are well-rested you're a much more efficient machine. Go to bed 30 minutes earlier. Leave something undone that night. If you're a parent, you most likely won't ever get it ALL done, so leave some of it undone in the name of a good night's rest. SO worth it. And truly, you'll feel stronger, more capable, more efficient and more joyful too so you can get more done more joyfully.
8. Lower your standards. At least temporarily. And think about what really matters. Got company coming and you're trying to get the baseboards shiny before they arrive? Or make the perfect shrimp dish for your cocktail party? Before you freak out or stress out or wither, ask yourself if what you're stressing about is worth it. Nobody's going to notice your baseboards. And if they do, do you really care? And don't you think your friends and family are coming to be with you and not coming to see a perfectly laid out Martha Stewart style spread? Sure, if you can do it all without stress or worry go for it, but if it's causing you to go into full on overload, is it really worth it? That's a rhetorical question by the way.
Three of the recurring themes of this season are peace, love and joy so it says on every card we've received. Be sure you set yourself up for a lot of both. Because really, isn't that the whole point of us being here on this earth anyway? I think so. This time of year and always.
If you want to make your holiday season slow down to just the tempo you like, check out the Create your Slow Holiday workbook. It'll totally get you exactly where you want to be.


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Attorney John R. Harrison practices in the areas of elder and special needs law. He assists older adults and individuals with special needs and their families with estate planning, Medicaid, guardianship, litigation, probate matters, and the maintenance of public benefits. He also works with public agencies throughout Ohio that provide services to individuals with developmental disabilities, mental illness, or who have substance abuse issues.
John spent the majority of his career working for Disability Rights Ohio, The Legal Aid Society of Columbus, and in private practice, where he advocated for the rights of people with disabilities of all ages in diverse civil matters. He gained significant litigation, mediation, and negotiation experience during this time. After working with individual clients for many years, John was inspired to tackle legal issues that affect the broader population. He strove to right injustices within our society, finding a way to do so by working with public agencies and county boards. Of note, he served as lead counsel in McQueen v. Cuyahoga County Probate Court, 135 Ohio St.3d 291, 2013 Ohio 65, which by a unanimous decision, the Ohio Supreme court guaranteed the right of a ward under guardianship who is unable to pay for an attorney for a review hearing, the right to have counsel appointed at court expense.
John is a member of the Ohio State Bar Association's Estate Planning, Trust and Probate Law Section and Elder and Special Needs Law Committee. He also serves on the Milestones Autism Organization board. He received his B.A. degree from the University of Michigan in 1990 and in 1995 he received his J.D. degree with honors from The Ohio State University Moritz College of Law. He is admitted to practice before the Courts of the State of Ohio, the U.S. District Courts for the Northern and Southern Districts of Ohio, and the U.S. Court of Appeals for the Sixth Circuit.
Phone: (216) 861-0360
Website: http://www.hickman-lowder.com/component/content/article/408-attorney-john-harrison