When  eight  months  was  reached  it  was  appreciated  that
the  child  was  far  from  normal,  for  the  swelling  of  the  face,
the  protrusion  of  the  large  and  swollen  tongue,  and  the
lack  of  mental  and  physical  development  were  painfully
apparent  to  all.  At  eleven  months  the  child  was  weaned,
and  the  dysphagia  was  so  marked  as  to  necessitate  feed-
ing with  a  dropper.  When  two  years  old  the  two  lower
incisors  appeared,  but  were  small  and  soon  discolored.
At  three  years  the  general  swelling  was  at  its  worst.
During  her  fourth  year  epileptiform  convulsions  were
frequent,  some  days  as  many  as  a  dozen.
