The  output  of  this  body  is  quite  constant  during  the  day  and  is
not  affected  by  diet,  hence  it  is  probably  not  a  non-nssiniilated  product
of  digestion.  It  seems  to  be  formed  in  the  bone-marrow.  Some  con-
nection with  the  granules  of  the  myelocytes  and  tumor  cells  is  sug-
gested.
This  albumose  can  be  demonstrated  in  ascitic  fluid,  blood,  and
bone-marrow.
Quantitatively  the  Esbach  tube  will  give  an  approximate  deter-
mination.
For  recent  literature  concerning  the  nature  of  the  substance  the
reader  is  referred  to  Simon. '^^

Albumosuria,  "  Ptptonuria." — Under  this  term  at  least  two  differ-
ent groups  of  bodies  have  been  described,— the  alx>ve-mentioned  rare
so-called  "  Bence- Jones'  body,"  which  because  of  its  many  reactions
was  counted  with  the  primary  proteoses,  and  a  group  of  bodies  having
nothing  in  common  with  the  above,  formerly  called  peptones,  a  name
based  on  Briicke's  definition  as  a  proteid  not  precipitated  by  K^FeCNg
and  acetic  acid.  By  "  peptone"  is  now  generally  understO(Hl  one  not
precipitated  by  complete  saturation  with  (NH4)2S04  (Kiihne),  and
judged  by  this  standard  these  bodies  are  chiefly  dcutero-albnmoses,
hence  the  name  "  peptonuria"  is  le,ss  used  and  "  albumosuria"  has
taken  its  place.  Yet  this  criterion  is  not  satisfactory  (Xenmeister) ;
also  true  peptone  judged  by  it  has  been  demonstratetl  in  the  albu-
mosuria of  croupous  pneumonia  and  other  diseases,  as  the  puer-
perium,  ulcer  of  the  stomach,  and  pulmonary  tulierculosis.  It  occurs
always  with  albumose  (the  reverse  is  not  true).'^*

In  testing  for  the  deutero-albumoscs  the  urine  should  l>e  albumin-
free,  and  if  this  is  not  the  case  it  should  be  made  so  by  the  Hofmeister
method.     Momer's  body  may  be  precipitated  by  basic  lead  acetate.
An  easy  test  is  to  saturate  the  urine  with  ammonium  sulphate,  a
floccutent  precipitate  indicating  albumose.
