Characterization of Bacterial Transcriptional Regulatory Networks in&lt;strong&gt; &lt;/strong&gt;&lt;em&gt;Escherichia coli&lt;/em&gt;&lt;strong&gt; &lt;/strong&gt;through Genome-Wide &lt;em&gt;in vitro&lt;/em&gt; Run-Off Transcription/RNA-SEq (ROSE)