Supplementary Methods from Primary Tumor Hypoxia Recruits CD11b&lt;sup&gt;+&lt;/sup&gt;/Ly6C&lt;sup&gt;med&lt;/sup&gt;/Ly6G&lt;sup&gt;+&lt;/sup&gt; Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche