John Travolta as James Ubriacco Kirstie Alley as Mollie Jensen George Segal as Albert Olympia Dukakis as Rosie Twink Caplan as Rona Joy Boushel as Melissa Abe Vigoda as Grandpa Vincent Ubriacco Christopher Aydon as Michael "Mikey '' Jensen (age 2 years) Jacob Haines as Mikey (age 1 year) Jaryd Waterhouse as Mikey (age 6 months) Jason Schaller as Mikey (fetus - newborn)
who played the baby in look whos talking
Christopher Aydon Jacob Haines Jaryd Waterhouse Jason Schaller