A 1, 2 - rearrangement or 1, 2 - migration or 1, 2 - shift or Whitmore 1, 2 - shift is an organic reaction where a substituent moves from one atom to another atom in a chemical compound. In a 1, 2 shift the movement involves two adjacent atoms but moves over larger distances are possible. In the example below the substituent R moves from carbon atom C to C.
when does a 1 2 hydride shift occur
a substituent moves from one atom to another atom in a chemical compound