Mark Jackson as Isaac, the Orville 's Science and Engineering Officer. Isaac is a member of the artificial, non-biological race from Kaylon - 1 that views biological lifeforms, including humans, as inferior. Isaac explains to Mercer in the pilot that the Union 's Admiralty offered a posting to any Kaylon willing to accept it, as an attempt to initiate relations between the two powers. Isaac accepted the offer because he saw it as a way to study human behavior. During the course of his time with the crew, he comes to observe and understand aspects of human behavior, such as sarcasm, slang, and practical jokes. Isaac perceives his surroundings with his body 's internal sensors, and not with the two glowing blue "eyes '' on his face, which are purely aesthetic.
who does the voice of isaac on the oroville
Mark Jackson