As implicated by the term “asynchronous development”, only cases showing deviations in the progress of remodelling of specific tissues relative to the progress of remodelling of other tissues should be considered.
Afin de ne pas sous-estimer la toxicité des substances chimiques fortement lipophiles, on envisagera d'ajouter de la nourriture au sédiment avant l'application de la substance d'essai (voir paragraphe 31).