Shares in semiconductor companies AMS AMS.S, STMicronelectronics STM.MI, Infineon Technologies IFXGn.DE and ASML ASML.AS lost between 0.3% and 1%, weighed down by supply chain woes that cost Apple Inc AAPL.O $6 billion in quarterly sales. The pan-European STOXX 600 .STOXX dropped 0.5% by 0711 GMT amid a nervous global mood fuelled by disappointing earnings updates from Wall Street's tech giants and persisting inflation fears. French aerospace group Safran SAF.PA rose 2.7% after it raised its full-year cashflow target, while re-insurer Swiss Re SRENH.S gained 3.3% after reporting strong net profit results as it recovers from the pandemic.