European markets were mostly lower with indices weighed down by poor results from Germany's Deutsche Bank ( DB ) and on disappointing phase 2 test results for a lung cancer treatment being developed by AstraZeneca (AZN). Wall Street set new records at Thursday's open as strong Q2 results coupled with the Federal Reserve's inclination to remain cautious while inflation gains traction fueled investor's appetite for risk. In earnings news, Facebook grabbed headlines with a strong Q2, while Twitter ( TWTR ) shares were drowning in negative territory after beating Wall Street's expectations, but reporting sluggish user growth.