But if it remains a problem next year, investors will surely feel less confident about the outlook," said Masayuki Murata, general manager of balanced portfolio investment at Sumitomo Life Insurance. With global supply disruption fuelling worries about inflation, investors are keeping close eye on whether the world's central banks will look to reduce their generous pandemic stimulus measures more quickly. MSCI's gauge of world stocks, ACWI, dipped 0.05% <.MIWD00000PUS> in early Thursday trade, with Japan's Nikkei .N225 leading the loss with fall of 1.1%.