These upsides keep Philip Morris International Inc. PM, Altria Group, Inc. MO and 22nd Century Group, Inc. XXII well-positioned amid hurdles associated with cost inflation and low cigarette volumes. Increased costs associated with smoke-free product research, development and marketplace activities have also been hurting margins. The Zacks Consensus Estimate for PM’s 2023 EPS has remained stable at $6.20 in the past 30 days.