There's a good chance you've seen Expedia's (NASDAQ: EXPE) Vrbo advertising somewhere lately, and Booking.com (NASDAQ: BKNG) has also upped its marketing efforts to get in front of travelers. The Federal Reserve is ready to raise interest rates to levels not seen in decades in an effort to combat rampant inflation, a move that could send the economy spiraling. In such a scenario, Airbnb's ability to profitably operate would be severely challenged, which naturally leaves investors wondering whether the vacation rental leader is still a worthwhile investment.