Amid a high inflationary environment and the U.S. Fed’s hawkish stance to contain it, Costco (NASDAQ:COST), Medical Properties Trust (NYSE:MPW), and Enbridge (NYSE:ENB) (TSE:ENB) could provide some respite to investors' worries in protecting their investment portfolios. Against this backdrop, let’s see how investors could protect their portfolios with COST, MPW, and ENB stocks. Costco (COST) Costco’s solid sales growth in 2022, stable margins, and earnings growth show that this warehouse retailer has managed inflation better than its peers by passing on the burden of higher costs to consumers.