Microstrategy (NASDAQ:MSTR) is one of the bigger buyers out there and is now holding a roughly $1 billion paper loss in the cryptocurrency. Tesla (NASDAQ:TSLA), Block (NYSE:SQ) and Ark Invest are big buyers and owners of Bitcoin, but their holdings have been crushed. Legendary trader and investor Paul Tudor Jones was one of the first big-name market participants to make the case for Bitcoin as a hedge against inflation.