In company news, Canadian Natural Resources LtdCNQ.TO narrowly missed analysts' estimates for first-quarter profit, as lower energy prices more than offset a rise in production for the country's largest oil and gas producer. May 4 (Reuters) - Futures for Canada's main stock index edged lower on Thursday, as markets digested mixed signals from the U.S. Federal Reserve, while gains in gold and crude prices limited the decline. Investors, however, took cues from Fed Chair Jerome Powell's statement that inflation remains a chief concern and it was too early to indicate if the monetary tightening cycle is near its end.