Novavax The first game-changing stock to buy to begin 2023 with a bang is one of the worst-performing healthcare stocks of 2022: Novavax (NASDAQ: NVAX). While the cost to invest in these projects has been sizable, the company was able to lean on historically low interest rates for over a decade, as well as its operating cash flow, to make it happen. Since cannabis is a nondiscretionary good -- i.e., people continue to buy it, even if the U.S. economy weakens or inflation picks up -- IIP can count on strong demand for its facilities.