By Karen Brettell and David Henry March 2 (Reuters) - Anxiety is building in bond and short-term funding markets over a pending regulatory change that could cause big Wall Street banks to pare their securities holdings and lending, industry sources said. The cost of such securities could reduce earnings per share at big banks by a couple of percentage points, Morgan Stanley analyst Betsy Graseck said in a recent report. Inflation fears helped to send yields on longer-dated Treasuries last week to one-year highs, while flooded money markets briefly sent a key overnight borrowing rate below zero.