Shares of Apple Inc AAPL.O slipped 0.8% in premarket trading, but Amazon.com Inc AMZN.O gained 1.1%. The benchmark S&P 500 .SPX ended 2.5% lower on Wednesday, marking its biggest percentage decline in almost a month, after the Fed raised rates by 75 basis points as expected, although Chair Jerome Powell said it was "very premature" to discuss when it might pause its increases. "Although the U.S. economy is beginning to decelerate, inflation remains stubbornly high, and the labor market is still very tight," said Paul O' Connor, head of multi-asset team at Janus Henderson Investors.