Technology megacaps slumped, including Google-parent Alphabet Inc GOOGL.O, Apple Inc AAPL.O, Microsoft Corp MSFT.O, Meta Platforms FB.O, Tesla Inc TSLA.O and Amazon.com AMZN.O. By David French May 5 (Reuters) - U.S. stocks closed Thursday sharply lower as investor sentiment cratered in the face of concerns that the Federal Reserve's interest rate hike would not be enough to tame surging inflation. IRPR Worries about Fed policy moves, mixed earnings from some big growth companies, the conflict in Ukraine and pandemic-related lockdowns in China have hammered Wall Street recently, overshadowing a better-than-expected quarterly reporting season.