Employee shall be employed by the Company to render services to the Company in the position of Chief Medical Officer and Head of Research & Development of the Company. Employee shall report directly to the President and Chief Executive Officer (the “ CEO ”). Employee shall use his good faith efforts to perform such duties and responsibilities and shall have such authorities as are normally related to such positions in accordance with the standards of the industry and any additional duties of an executive nature the CEO now or hereafter assigns to Employee consistent with his position as the Company’s Chief Medical Officer and Head of R&D. The principal place of Employee’s employment under this Agreement shall be Santa Barbara, California, it being understood that periodically Employee shall also be required to work at the Company’s offices in Orange County, California (collectively, “ Company Offices ”).