Subject to the direction and authority of the Board of Directors of the Company (the “ Board ”), the Employee shall have direct responsibility for the day to day management and advancement of the Company’s biologic manufacturing activities, including responsibility for all Chemistry and Manufacturing Control (“ CMC ”) processes of PRO 140, including, without limitation, managing consultants of the Company with respect to CMC-related issues. In addition, the Employee will advise the Chief Executive Officer of the Company on all tactical and strategic issues related to CMC matters. The Employee shall report to, and be subject to the lawful direction of, the CEO. The Employee agrees to perform to the best of his ability, experience, and talent those acts and duties, consistent with the position of Chief Technology Officer – Head of Process Sciences, Manufacturing & Supply Chain as the CEO shall from time to time direct. During the Term, the Employee also shall serve in such other Employee-level positions or capacities as may, from time to time, be reasonably requested by the CEO.