Sekyi kɔɔ sukuu wɔ Mfantsipim School na osuaa abɔde nyansapɛ mu wɔ suapɔn a ɛne University of London, bre a ne nana barima de no kɔɔ Bretain. Na ne botae ne sɛ ɔbɛyɛ mfiridwuma dwomfo te sɛ ne wɔfa a ɔne J.B Essuman – Gwira yɛe no, nanso na n’awofo yɛ nea wɔpɛ sɛ ɔyɛ mmaranimfo nti saa adwuma no na ɔde ne ho hyɛɛ mu. Wɔfrɛɛ no kaa amanɔne mmaranimkuo a ɛne English Bar wɔ Inner Temple wɔ afe 1918. Sekyi bɛyɛɛ mmaranim fo Gold Coast. ɔyɛ kane kandifo ma adwumakuo a ne din de Aborigines’ Rights Protection Society, kuo Ntional Congress of British West Africa mu ni, ne kuo a ne din de Coussey Committee a wɔhwɛɛ amanmara nsesae. Ɔwaree Lilly Anna Cleaned a n’awofo yɛ John Peter Clean ne Elizabeth Vroom. Kobina Sekyi wui wɔ Cape Coast wɔ june da a ɛtɔ so 20, afe 1956.