Fi afe 1954 kosi 1957 no, Kofi Annan kɔɔ Mfantsipim Skuul a ɛwɔ Cape Coast na ɛhɔ na osuaaa tema ne ahobrɛase. Wɔ 1957 a Annan wiee Mfantsipim Skuul no, ɔman Ghana nyaa faahodie a na ɔyɛ abibimana a edi kan. Wɔ 1958 mu no, Kofi Annan toaa adesua so wɔ Kumasi College of Science and Technology a afei wɔato no Kwame Nkrumah University of Science and Technology. Ɔfaa Ford Foundation nhyehyɛe so kɔɔ Macalester College wɔ St. Paul, Minnesota wɔ 1961 mu. Ɔkɔɔ adesua no so wɔ Graduate Institute of Information Studies wɔ Geneva, Switzerland fi 1961 kosi 1962. Fi 1971 kosi 1972 no ɔbɔɔ no ho mmɔden nyaa Master of Science abasobɔ fii MIT Sloan School of Manaagement hɔ.