Gastrin and interleukin-1beta stimulate growth factor secretion from cultured rabbit gastric parietal cells.
The hormone gastrin stimulates proliferation of the gastric mucosa. Infl
ammatory cytokines, such as interleukin-1beta (IL-1beta), are also produced in the stomach and may be involved in the regulation of gastric mucosal growth. The aim of this study was to investigate the effect of gastrin and IL-1beta on the secretion of growth factors from cultured rabbit gastric parietal cells.