Our long-term objective has been to develop noninvasive techniques for studying the human retina for both basic science and clinical purposes. By applying current theories of phototrans
duction to the human retina, we have developed a new technique for measuring the light-induced changes in the human retina. This technique, called the electroretinogram (ERG), is based on the fact that the retina is a light-sensitive tissue. The ERG is a measure of the electrical activity of the