The SCID mouse as a vehicle to study autoimmunity.
Peripheral blood mononuclear cells (PBMC) injected into severe combined immune deficiency (SCID
) mice develop into a variety of cell types, including T cells, B cells, and macrophages. The SCID mouse is a useful model for studying the development of autoimmunity. In this review, we discuss the use of the SCID mouse as a model for studying the development of autoimmunity. We also