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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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In Citric acid cycle, which enzyme is inhibited by arsenite?
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The correct answer is  Ans. is 'b' i.e., a ketoglutarate DehydrogenaseArsenite binds to the sulfhydryl group and hence inhibits the activity of enzymes which have lipoamide in the active site, Hence Arsenite inhibits Pyruvate Dehydrogenase and a ketoglutarate dehydrogenase of citric acid cycle, It is an example for non competitive inhibition, Succinate dehydrogenase is inhibited by malonate.