system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 44-year-old woman comes to the physician with increasingly yellow sclera and pruritus over the past 3 months. She has intermittent right-upper-quadrant pain and discomfort. She has no history of any serious illnesses and takes no medications. Her vital signs are within normal limits. Her sclera are icteric. Skin examination shows linear scratch marks on the trunk and limbs. The remainder of the physical examination is unremarkable. Laboratory studies show:
Complete blood count
Hemoglobin 15 g/dL
Mean corpuscular volume 95 μm3
Leukocyte count 6,000/mm3 with a normal differential
Serum
Alkaline phosphatase 470 U/L
Aspartate aminotransferase (AST, GOT) 38 U/L
Alanine aminotransferase (ALT, GPT) 45 U/L
γ-Glutamyltransferase (GGT) 83 U/L (N=5–50 U/L)
Bilirubin, total 2.7 mg/dL
Bilirubin, direct 1.4 mg/dL
Magnetic resonance cholangiopancreatography (MRCP) shows a multifocal and diffuse beaded appearance of the intrahepatic and extrahepatic biliary ducts. Which of the following is the most appropriate diagnostic study at this time?
assistant
Rectosigmoidoscopy