system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Arthritis mutilans is a feature of?
assistant
The correct answer is  Ans. b (Psoriasis). (Ref. Harrison' sprinciples of medicine -18th/Chapter 52.)PSORIASIS# Classical features:- White scaly plaques with specific distribution over the body.- Pitting (thimble) of nails.- Onychodystrophy, Subungual hypertrophy.- Arthritis mutilans, rare and late feature {pencil in cup sign, pestle in mortar sign). (MH 2008)# Treatment:- Unstable psoriasis = liberal application of topical bland emollient & supportive therapy.- PUVA therapy is used in severe cases.- Oral methotrexate, retinoids, cylosporin can be used, however systemic steroids are usually avoided for the fear of precipitating pustular psoriasis upon withdrawal.