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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, METHODS, METHODS, METHODS, RESULTS. Meshes: Adult, Aged, Chronic Disease, Female, Gait, Humans, Male, Middle Aged, Physical Therapy Modalities, Postural Balance, Recovery of Function, Spinal Cord Injuries, Walking, Young Adult.
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Does intermittent hypoxia and locomotor training enhance dynamic but not standing balance in incomplete spinal cord injury patients? Context: To test the effect of combined intermittent hypoxia (IH) and body weight-supported treadmill training (BWSTT) on standing and dynamic balance in persons with incomplete spinal cord injury (iSCI). Randomized, triple-blind, placebo-controlled study. "Instituto Teletón Santiago" and "Hospital Clínico Mutual de seguridad" in Santiago, Chile. Persons with ASIA C and D chronic iSCI (> 1 year post-injury) were randomly assigned to either IH plus BWSTT (n=18) or continued normoxia (Nx, placebo) plus BWSTT protocol (n=17). Participants received either IH (cycling 9/21% O Standing balance (normalized Jerk: nJerk, root mean square: RMS) and dynamic balance (turning duration, cadence in a turn, and turn-to-sit duration), were assessed before and after IH/Nx protocol by means of instrumented sway (iSway) and timed up and go test (iTUG). There was no significant difference in standing balance between interventions for both nJerk and RMS iSway components (both p>0.05). There was a significantly faster cadence (p<0.001), turning duration (p<0.001), and turn-to-sit duration (p=0.001) in subjects receiving IH plus BWSTT, compared to placebo.
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A 4-week protocol of IH combined with locomotor training improves dynamic, but not standing balance, in persons with iSCI. Final Decision: yes