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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Aged, Aorta, Thoracic, Blood Vessel Prosthesis Implantation, Cerebrovascular Circulation, Chi-Square Distribution, Elective Surgical Procedures, Female, Heart Arrest, Induced, Humans, Hypothermia, Induced, Kaplan-Meier Estimate, Logistic Models, Male, Middle Aged, Odds Ratio, Operative Time, Perfusion, Proportional Hazards Models, Retrospective Studies, Risk Factors, Stroke, Time Factors, Treatment Outcome.
user
Is hypothermic circulatory arrest using antegrade cerebral perfusion safe for elective aortic arch surgery? Context: We hypothesized that hypothermic circulatory arrest (HCA) can be performed with a low operative risk and does not add to the morbidity in elective procedures. A total of 178 patients with a mean (± SD) age of 62 (± 10) years underwent HCA for elective aortic surgery from April 2008 to September 2011. Pre- and postoperative clinical data were collected prospectively. Hemiarch replacement was performed in 97% patients. Mean logistic Euroscore I was 17% (± 15). HCA was performed at 26°C bilateral tympanic temperature. Mean HCA duration was 17 (±) min. Mean cross-clamp time was 106 (± 39) min. Overall 30-day mortality was 2% and stroke occurred in 4% of patients. Overall 6-month survival was 96%. Cox regression analysis for 6-month survival revealed four variables with significant influence: the logistic Euroscore I (p = 0.008), age (p = 0.04), cross-clamp time (p = 0.008), and reoperation for bleeding complications (p = 0.04).
assistant
HCA with open distal anastomosis for elective aortic repair can be performed with low operative mortality, even in the elderly, and seems not to add to the morbidity of the procedure. Final Decision: yes