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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Abdominal Wall, Adult, Angiography, Body Mass Index, Epigastric Arteries, Female, Humans, Mammaplasty, Middle Aged, Monitoring, Intraoperative, Prospective Studies, Surgical Flaps, Tomography, X-Ray Computed, Weight Gain, Weight Loss.
user
Is perforator dilatation induced by body weight gain reversed by subsequent weight loss : implications for perforator flaps? Context: Perforator flaps frequently rely on small vessels for their supply, which may lead to problems with flap viability. To ensure a more dependable blood supply, larger perforators are sought either on preoperative imaging or intraoperatively. Body weight gain is usually associated with increasing cutaneous perforator size. The question remains whether body weight loss causes a diminution in the size of these perforators. Sixty-seven consecutive patients were recruited, each undergoing either deep inferior epigastric perforator flap breast reconstruction (n = 57) or abdominoplasty (n = 10), with measurement of all abdominal wall deep inferior epigastric artery perforators. This was calculated with either preoperative computed tomographic angiography scans or intraoperative measurements. Higher body mass index (>29) was associated with a 2.7-fold increase in number of 1.5-mm perforators (p < 0.01), a 1.3-fold increase in the average diameter of the five largest perforators (p < 0.01), and a 1.2-fold increase in the diameter of the largest perforator (p < 0.01). Subsequent loss of body weight did not reduce the size of perforators. Patients who had been previously heavier had an average of a 2.6- to 3.3-fold increase in the number of perforators larger than 1.5 mm (p < 0.01) and a 1.2-fold increase in the average diameter of the five largest perforators.
assistant
Body weight gain results in irreversible dilatation of the cutaneous perforators of the abdominal wall, with subsequent body weight loss not decreasing the size of perforators, facilitating optimal flap harvest in perforator flap surgery. Patients can therefore be advised to lose weight preoperatively, with benefit to both flap harvest and operative outcomes. Final Decision: no