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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Atherosclerosis, Biomarkers, Carotid Intima-Media Thickness, Cytomegalovirus, Cytomegalovirus Infections, DNA, Viral, Female, Humans, Leukocytes, Mononuclear, Male, Middle Aged, Oxidative Stress, Virus Latency.
user
Is presence of cytomegalovirus DNA in leucocytes associated with increased oxidative stress and subclinical atherosclerosis in healthy adults? Context: Investigate the latent cytomegalovirus (CMV) infection as a biomarker of oxidative stress and atherosclerosis. Latent CMV infection was diagnosed in healthy individuals with PCR-evidence of CMV DNA in peripheral leucocytes. Oxidative stress and atherosclerosis were measured by mitochondrial DNA oxidative damage index (mtDNA(ΔCT)) and intima media thickness (IMT). The CMV DNA positive subjects had a higher mean mtDNA(ΔCT) and greater IMT than subjects in the control group.
assistant
Presence of CMV DNA in leucocytes, as a marker of latent CMV infection, was associated with increased levels of oxidative stress and subclinical atherosclerosis in healthy adults. Final Decision: yes