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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Animals, Cohort Studies, Cross-Sectional Studies, Diet, Erythrocytes, Fatty Acids, Omega-3, Fatty Acids, Omega-6, Female, Fishes, Humans, Lipids, Pregnancy, Prospective Studies, Washington.
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Are maternal erythrocyte omega-3 and omega-6 fatty acids , and plasma lipid concentrations , associated with habitual dietary fish consumption in early pregnancy? Context: We investigated the relationship between selected maternal erythrocyte omega-3 and omega-6 polyunsaturated fatty acids (PUFA) and plasma lipids in early pregnancy and reported habitual fish consumption during the periconceptional period. This cohort study included 923 pregnant women who reported periconceptional dietary habits and provided a blood sample before 20 weeks of gestation. PUFA was determined by gas chromatography and plasma lipids by standard enzymatic methods. Differences in erythrocyte PUFA and plasma lipid concentrations were estimated using linear regression. Mean erythrocyte eicosapentanoic acid and other PUFA content (%/total) were positively associated with frequency of self-reported fish consumption. Arachidonic acid was inversely related with frequent fish consumption (p trend <0.001). Women who consumed fish >twice/week had lower plasma triglyceride (-11.5 mg/dl) and higher HDL-cholesterol (+2.8 mg/dl) concentrations than women consuming fish <once/week.
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These results support findings of inverse relation between fish consumption and preeclampsia risk. Final Decision: yes