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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, METHODS, RESULTS. Meshes: Accidental Falls, Aged, Aged, 80 and over, Biomarkers, Clinical Laboratory Techniques, Echocardiography, Doppler, Emergency Service, Hospital, Female, Heart Diseases, Humans, Male, Prospective Studies, Takotsubo Cardiomyopathy, Troponin I.
user
Does clinical significance of unsuspected rise in cardiac troponin in the setting of fall in older people? Context: To assess the clinical significance of unsuspected rise in cardiac troponin I (cTnI) levels in elderly patients who have fallen. Monocentre prospective observational pilot study. Consecutive elderly patients (age >65 years) referred to the emergency department after being immobilised on the ground after a fall. Clinical, laboratory and Doppler echocardiography data were collected on admission to assess the cardiac correlates of increased cTnI. The survival endpoint was a composite of death or cardiovascular event. 60 patients were included in this study. Mean age was 81+/-8 years. Cardiac TnI was > or =0.05 ng/ml in at least one blood sample in 40 patients (67%). New diagnosis of cardiac disease was performed in 14 patients, 13 of them had cTnI > or =0.05 ng/ml. Transient apical ballooning was diagnosed in six patients. During a median follow-up of 92 (49-131) days death occurred in six patients, myocardial infarction in three, stroke in one and acute heart failure in five. Cardiac TnI > or =0.05 ng/ml was a predictor of these events (p=0.034).
assistant
An unsuspected rise in cTnI correlates with new diagnosis of cardiac disease and is a potential marker of stress induced cardiomyopathy in elderly patients who fall. Cardiac TnI might be a strong predictor of outcome in these patients. Final Decision: yes