system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
What is mechanism of action of curonium drugs as muscle relaxant?
assistant
The correct answer is  Persistently depolarizing at neuromuscular junction - propey of succinylcholine depolarising eg : succinylcholine 1. MOA - persistent / prolonged depolarising of nicotinic cholinergic receptors 2. fasiculation seen 3. post operative myalgia 4. not reversed by neostigmine 5. train of four response not seen 6. TOF ratio (B/A = 1 ) 7. neuromuscular monitoring not done 8. no post tetanic facilitation non - depolarising 1. MOA - competitive antagonist 2. fasiculation not seen 3. no post operative myalgia 4. reversed by neostigmine 5. train of four response seen 6. TOF ratio (B/A< 1 ) 7. neuromuscular monitoring done 8. post tetanic facilitation seen