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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Fluroquinolone mechanism of action in gram positive organism is by -
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The correct answer is  Ans. is 'd' i.e., Topoisomerase IV o The FQs inhibit the enzyme enzyme bacterial DNA gyrase in gram negative bacteria. In the gram - positive bacteria the major target of FQ action is a similar enzyme topoisomerase IV which nicks and separates daughter DNA strands after DNA replication.