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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, METHODS, RESULTS. Meshes: Adult, Aged, Anxiety, Chi-Square Distribution, Cross-Sectional Studies, Electrocardiography, Ambulatory, Female, Humans, Independent Living, Linear Models, Logistic Models, Male, Middle Aged, Multivariate Analysis, Norway, Odds Ratio, Personality Assessment, Prevalence, Risk Assessment, Risk Factors, Tachycardia, Ventricular, Time Factors, Type D Personality, Ventricular Premature Complexes.
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Is type D personality associated with increased prevalence of ventricular arrhythmias in community-residing persons without coronary heart disease? Context: Type D personality may be a risk factor for poor outcome in patients with cardiovascular disease. The biological mechanisms underlying this association are poorly understood. The objective of the study was to test the hypotheses that Type D personality is associated with biological markers for sympathetic dysregulation. Cross-sectional community-based study. Type D personality was evaluated by DS-14 in 450 persons (46% men), aged between 30 and 65 years. From a Holter-recording, (mean length 18.3 hours), long-term heart rate, ventricular arrhythmias, and heart rate variability (HRV) were registered as markers of sympathetic dysregulation. Traditional cardiovascular risk factors, apnoea-hypopnoea index, medication, and anxiety symptoms were adjusted for. Type D persons had higher long-term averaged heart rate (74 vs. 71 beats/min, p = 0.003), but this difference was attenuated and not significant in the multivariate model (p = 0.078)). There was an increased prevalence of complex ventricular ectopy (bigeminy, trigeminy, or non-sustained ventricular tachycardia; 14 vs. 6%, p = 0.005 in multivariate model). HRV indices did not differ significantly between those with or without Type D personality. Anxiety symptoms did not confound these associations.
assistant
Type D personality is independently associated with a higher likelihood of ventricular arrhythmias, which may be implicated in the increased cardiovascular risk observed in persons with Type D personality. Final Decision: yes