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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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An energy drink that claims to improve athletic performance is being investigated by a group of scientists for its mechanism of action. Although its exact mode of action is unknown, an active substance in the drink is thought to increase the activity of an ATPase involved in muscle contraction. By radiolabeling the active substance, scientists are able to trace it binding to an allosteric site on globular portions of a heavy chain dimer where it binds with greater affinity during muscle relaxation but with lesser affinity when the globular head binds with another contractile protein. What portion of the sarcomere shown below will have the greatest affinity of the substance during muscle contraction?
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II (represented on image as H band)