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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: PURPOSE, METHODS, RESULTS. Meshes: Abnormalities, Multiple, Anti-Bacterial Agents, Audiometry, Diuretics, Early Diagnosis, Extracorporeal Membrane Oxygenation, Female, Follow-Up Studies, Hearing Loss, Sensorineural, Hernia, Diaphragmatic, Hernias, Diaphragmatic, Congenital, Herniorrhaphy, High-Frequency Ventilation, Humans, Infant, Newborn, Male, Neonatal Screening, Neuromuscular Blocking Agents, Nitric Oxide, Ontario, Oxygen Inhalation Therapy, Postoperative Complications, Prevalence, Risk Factors, Survivors.
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Hearing loss in congenital diaphragmatic hernia (CDH) survivors: is it as prevalent as we think? Context: The incidence of sensorineural hearing loss (SNHL;>20 dB loss) in CDH survivors is debated. We evaluated long-term audiological outcomes at a single tertiary care center with ECMO capability and an established neonatal follow-up program. With REB approval, records of CDH survivors from 2000 to 2010 were retrospectively analyzed. Demographic, postnatal, and audiometric information was gathered. All underwent auditory brainstem response (ABR) or otoacoustic emissions screening before discharge and complete audiological surveillance. Thirty-three patients were evaluated to age 4+ years with others continuing follow-up. Forty-three patient records were reviewed with 1 excluded (transferred to another institution). Median GA and BW were 39 weeks (35-41) and 3.1 kg (2-4), respectively. Median ventilation days were 10 (2-189) with 34 infants ventilated 5+ days. Sixteen (36%) received HFOV, 21 (49%) iNO, and 5 (12%) ECMO. The median time to CDH repair was 3 days (1-23), and 11 (26%) required patch repair. Nine infants (21%) received diuretics and oxygen after discharge. Audiological surveillance identified only one patient with SNHL (received HFO, iNO, and patch repair).
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Neonatal screening identifies CDH survivors at risk for hearing difficulties but must be followed with comprehensive testing until school age. The incidence of SNHL may be less than previously reported in this population.