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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: METHOD, RESULTS. Meshes: Adult, Aged, Blood Pressure, Cardiovascular Diseases, Cohort Studies, Compliance, Female, Humans, Kidney Failure, Chronic, Male, Middle Aged, Predictive Value of Tests, Pulsatile Flow, Renal Dialysis, Risk Factors.
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Haemodialysis-unresponsive blood pressure: cardiovascular mortality predictor? Context: Aortic PWV was evaluated in a limited care HD cohort, all of whom were asymptomatic of cardiovascular disease. Of 47 limited care patients, 45% were classified as HD responsive, with a 17% fall in mean arterial pressure compared with a 6% increase in the HD-unresponsive group. While there were no significant differences between the two groups in traditional vascular disease risk factors or interdialytic weight loss, PWV was significantly elevated in the HD-unresponsive group (12.9 +/- 2.7 compared with 10.8 +/- 2.9; P<0.05). Furthermore, there was a positive correlation between the change in BP during HD and PWV in all subjects (r = 0.500; P<0.001 for systolic blood pressure (SBP), a correlation that also existed for diastolic blood pressure (DBP) (P<0.01).
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This study suggests that patients with HD-unresponsive BP are more likely to have vascular disease and this association between PWV and HD-induced BP changes might partly explain the apparent paradox of pre- and post-HD BP with mortality. It is proposed that a population with elevated post-HD BP is more likely to be composed of subjects with vascular disease (overt or occult), in contrast to a group with high pre-HD BP, which will be more heterogeneous.