system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adolescent, Adult, Aged, Aged, 80 and over, Aging, Blinking, Child, Dry Eye Syndromes, Female, Humans, Male, Middle Aged, Reproducibility of Results, Surface Tension, Tears, Tomography, Optical Coherence, Young Adult.
user
Do age-related changes in tear menisci imaged by optical coherence tomography? Context: To determine age-related changes of tear menisci in healthy subjects and to compare tear variables between age-matched normals and dry eye subjects. Anterior segment optical coherence tomography was used to measure upper and lower tear menisci in healthy subjects (n = 197, 8-83 years) and in age-matched dry eye patients (n = 38, 19-72 years). Measured tear variables included the height and area of the tear meniscus. Tear meniscus volumes were calculated based on the cross-sectional areas of the tear menisci and the eyelid lengths. The age-related decrease rates of the tear menisci were also calculated. There were significant negative correlations between age and all tear meniscus dimensions (r ranged from -0.649 to -0.753; p < 0.05) in the healthy group. The rate of decrease for the total tear meniscus volume in healthy subjects was 1.0% per year. Compared with age-matched healthy subjects, the height, cross-sectional area, and volume of the upper and lower tear menisci in dry eye subjects were significantly smaller (p < 0.05).
assistant
Tear menisci decreased with age in the healthy group. The variables in age-matched dry eye subjects were significantly lower than those in the healthy group. Final Decision: yes