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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adolescent, Adult, Aged, Aged, 80 and over, Case-Control Studies, Comorbidity, Female, Hospital Mortality, Humans, Incidence, Length of Stay, Longitudinal Studies, Male, Middle Aged, Puerto Rico, Retrospective Studies, Risk Factors, Subarachnoid Hemorrhage, Survival Rate, Treatment Outcome, Vitamin D Deficiency, Young Adult.
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Is vitamin D deficiency associated with outcomes in aneurysmal subarachnoid hemorrhage patients , a case control study? Context: Vitamin D deficiency has been associated with increased risk and adverse outcomes in many clinical settings including cardiovascular disease, stroke, and critically ill patients. Therefore we aimed to determine whether vitamin D deficiency had any effect in aneurysmal subarachnoid hemorrhage (aSAH) clinical outcomes. A retrospective record review was conducted in a tertiary community hospital in Puerto Rico. Adult patients admitted to the neurosurgical intensive care unit (NICU) with a diagnosis of aSAH from January 2013 to July 2014, who had a 25-hydroxyvitamin-D level drawn, were included. A total of 40 patients were admitted with a diagnosis of aSAH and 33 met the inclusion criteria. Overall, 81% of patients were vitamin D deficient or insufficient. Subjects were grouped into those with vitamin D deficiency (n=13) and those without (n=20). Except for a larger prevalence of coronary artery disease, all other baseline parameters were similar. No significant difference in hospital mortality was observed (p=0.676). The percentage of vasospasms, vasopressor use, hydrocephalus, and infections was also similar. An increase in length of NICU stay and respiratory failure was observed in the vitamin D deficient group but it was not statistically significant.
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A high prevalence of vitamin D deficiency and insufficiency was found among patients admitted with a diagnosis of aSAH in this cohort. Despite this no difference in clinical outcomes was observed in patients when compared by vitamin D group. Further studies are needed to assess potential effects of vitamin D deficiency in this patient population including long term follow-up after discharge. Final Decision: no