system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Clotting factors that is not affected in liver disease is?
assistant
The correct answer is  Factor VIII REF: Ganong's 22nd ed p. 545 All clotting factors except VIII are produced by liver, which is produced by vascular endothelium