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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 55-year-old man comes to the emergency department because of severe chest pain for the past hour. The patient describes the pain as located in the middle of his chest, tearing in quality, and radiating to his back. He has a history of hypertension, hyperlipidemia, and type 2 diabetes mellitus. He has smoked a pack of cigarettes daily for the past 30 years. He drinks 2–3 beers daily. He used cocaine in his 30s, but he has not used any illicit drugs for the past 15 years. Medications include enalapril, atorvastatin, and metformin. He says that he has not been taking his medications on a regular basis. He is 174 cm (5 ft 9 in) tall and weighs 98 kg (216 lb); BMI is 32 kg/m2. His pulse is 80/min, and blood pressure is 150/90 mm Hg in his right arm and 180/100 mm Hg in his left arm. Cardiac examination shows a high-pitched, blowing, decrescendo early diastolic murmur. An ECG shows no abnormalities. An x-ray of the chest shows a widened mediastinum. Which of the following is the strongest predisposing factor for this patient's condition?
assistant
Hypertension