system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Gene affected in breast cancer?
assistant
The correct answer is  Ans. is 'b' i.e., p53 * Most common gene involved infamilial breast cancer - BRCA-1* Most common gene involved in sporadic breast cancer -p53* Most common gene involved overall (Hereditory plus sporadic) - p53* Maximum increase in susceptibility to breast cancer is seen with - p53 mutation (>90%) whether it is sporadic or Hereditary.