system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following trigger onset of labour?
assistant
The correct answer is  Fetal ACTH acts on fetal adrenal gland causing release of DHEA and DHEA sulphate which are used by the placenta along with the other enzymes like Sulfatase ,Aromatase, 3 B hydroxysteroid dehydrogenase, 17 B hydroxysteroid dehydrogenase -Conveing into Estriol and Estardiol that help in triggering the labour. Ref: Williams Obs 24e pg 108-109.