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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, METHODS, METHODS, METHODS, RESULTS. Meshes: Adult, Birth Weight, Chi-Square Distribution, Female, Fertility, Fertilization in Vitro, Humans, Infant, Newborn, Infant, Small for Gestational Age, Infertility, Logistic Models, Middle Aged, Multivariate Analysis, Odds Ratio, Oocyte Donation, Perinatal Death, Pregnancy, Premature Birth, Registries, Retrospective Studies, Risk Assessment, Risk Factors, Treatment Outcome, United States.
user
Are donor oocytes associated with preterm birth when compared to fresh autologous in vitro fertilization cycles in singleton pregnancies? Context: To use a national registry to examine the role of oocyte donation on pregnancy outcomes in singleton pregnancies. Retrospective cohort. Not applicable. Women undergoing autologous cycles and donor oocyte recipients in the United States from 2008-2010. None. Preterm delivery, birth weight <2,500 g, small for gestational age birthweight, perinatal death. The rates of preterm delivery and low birthweight for all members of this cohort were higher than the US national average. Pregnancies resulting from oocyte donation were significantly more likely to end before 34 weeks' and 37 weeks' gestation (adjusted odds ratio [OR] = 1.30, 95% confidence interval [CI] = 1.03-1.64 for 34 weeks' gestation, adjusted OR = 1.28, 95% CI = 1.12-1.46 for 37 weeks' gestation), and to result in infants weighing <2,500 g (adjusted OR = 1.21, 95% CI = 1.02-1.44). However, once gestational age at delivery is accounted for, these infants are actually at decreased risk of having a small for gestational age birthweight (adjusted OR = 0.72, 95% CI = 0.58-0.89) and of perinatal death (adjusted OR = 0.29, 95% CI = 0.09-0.94).
assistant
Data from a national cohort indicate that donor oocyte recipients are more likely to deliver preterm when compared with autologous patients. The effect of donor oocyte donation on birthweight is likely a function of an increased rate of preterm delivery among this population. Final Decision: yes