system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Initiating event of Endotoxic shock
assistant
The correct answer is  The receptor for the endotoxin in humans is the TLR-4 located on the surface of antigen presenting cells. b. Binding to the receptor activates a cascade of enzymatic reactions which finally leads to the activation of the genes for the proinflammatory cytokines. Ref ganong's review of medical physiology 25e p465