system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, METHODS, METHODS, METHODS, RESULTS. Meshes: Administration, Intravaginal, Adult, Blood Loss, Surgical, Blood Transfusion, Female, Humans, Leiomyoma, Misoprostol, Prospective Studies, Uterine Neoplasms.
user
Is use of a single preoperative dose of misoprostol efficacious for patients who undergo abdominal myomectomy? Context: To investigate the effectiveness of a single preoperative dose of misoprostol in abdominal myomectomies. Placebo-controlled randomized prospective study. Department of obstetrics and gynecology in a university hospital. Twenty-five women with symptomatic uterine leiomyomas. Among patients undergoing abdominal myomectomies, an hour before the operation women in the study group (n = 13) were given a single dose of vaginal misoprostol (400 microg); those in the control group (n = 12) were given placebo. Intraoperative blood loss, duration of operation, duration of postoperative hospitalization, and the need for blood transfusion were compared between the control and study groups. Blood loss, operation time, and need for postoperative blood transfusion were significantly reduced in the group given vaginal misoprostol. No difference was observed among patients in terms of the time of hospitalization.
assistant
A single preoperative dose of vaginal misoprostol is a simple, reliable method for reducing intraoperative blood loss and need for postoperative blood transfusion after abdominal myomectomies. Final Decision: yes