system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following is a differential of giant cell tumor?
assistant
The correct answer is  Eccentric lytic lesion with no calcification is the commonest differential. Calcification: Ossifying fibroma, chondroblastoma osteosarcoma hence non-ossifying fibroma is a preferred answer here. Non-ossifying fibroma Benign (non-cancerous) Eccentric Age <15 years Non-aggressivetumor Metaphyseal lesion Sclerotic margin Histologically Giant cell with foam cell Note: Closest differential is ABC.