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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Aged, Aged, 80 and over, Alzheimer Disease, Cognition, Dementia, Female, France, Humans, Language, Linear Models, Male, Middle Aged, Neuropsychological Tests, Observer Variation, ROC Curve, Reproducibility of Results.
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Is the Addenbrooke 's Cognitive Examination Revised as effective as the original to detect dementia in a French-speaking population? Context: This paper presents the validation of the French version of the Addenbrooke's Cognitive Examination Revised (ACE-R). The variability of the 3 versions of the ACE-R (A, B and C), performed by the same observer, hence mainly 2 or 3 times on 119 patients showing no progression, was first calculated by Cronbach's alpha coefficient, t test and linear regression. The alpha coefficients of the 3 versions were obtained showing that the ACE-R versions can be considered as one, and an analysis of the interobserver variability was performed by Cohen's kappa coefficient, t test and linear regression on 12 patients. Eventually, we performed a receiver operating characteristic (ROC) analysis to compare the sensitivities and specificities to detect dementia of the ACE, the ACE-R and Mini Mental State Examination on 319 consecutive patients. The ROC areas of sensitivities and specificities of the ACE and ACE-R were very similar. Two cutoffs were identified at 83/100 and 89/100 with a specificity to normality of 98.6% if the ACE-R score was ≥83 and a sensitivity to dementia of 98.4% if the ACE-R score was ≤89.
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ACE-R in French is as reliable and valid as the original version to detect dementia. Final Decision: yes