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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Which of the following is the most effective drug against M. leprae ?
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The correct answer is  Rifampicin is the only bactericidal drug amongst the anti leprosy drugs & can render Leprosy rapidly non contagious. It acts by inhibiting mycobacterial DNA dependent RNA synthesis. Ref: Essentials of Medical Pharmacology By KD Tripathi, 5th Edition, Pages 700, 709-11, 713.