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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adolescent, Adult, Aged, Aged, 80 and over, Arthroplasty, Replacement, Hip, Body Mass Index, Databases, Factual, Humans, Incidence, Middle Aged, Obesity, Overweight, Prosthesis-Related Infections, Risk Factors, Young Adult.
user
Does meta-analysis show that obesity may be a significant risk factor for prosthetic joint infections? Context: Our aim was to evaluate the association between the different degree of obesity and prosthetic joint infections (PJIs) after total hip replacement (THR) by performing a meta-analysis. PubMed, Cochrane library and Embase databases up to May, 2014 were retrieved for identifying relevant studies. Relative risk (RR) and their 95 % confidence intervals (CIs) were used as effect sizes. A total of 15 articles were included in this meta-analysis. The overall analyses showed that the risk of PJIs in the BMI ≥ 30 group and in BMI ≥ 40 group were significantly higher than that in the BMI < 30 group. As well, the prospective pooled results showed that overweight and obesity could significantly increase the incidence of PJIs.
assistant
Our meta-analysis indicates that all of obesity levels can significantly increase the risk of PJIs. However, further studies with more strict design are need in the future. Final Decision: yes