system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 44-year-old woman presents to the emergency department with jaundice and diffuse abdominal pain. She denies any previous medical problems and says she does not take any medications, drugs, or supplements. Her temperature is 97.6°F (36.4°C), blood pressure is 133/87 mmHg, pulse is 86/min, respirations are 22/min, and oxygen saturation is 100% on room air. Physical exam is notable for sclera which are icteric and there is tenderness to palpation over the right upper quadrant. Laboratory studies are ordered as seen below.

Hepatitis B surface antigen: Positive
Hepatitis B surface IgG: Negative
Hepatitis B core antigen: Positive
Hepatitis B core IgG: Positive
Hepatitis B E antigen: Positive
Hepatitis B E IgG: Positive

Which of the following is the most likely diagnosis?
assistant
Chronic hepatitis B infection