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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Acoustic Stimulation, Adolescent, Analysis of Variance, Attention Deficit Disorder with Hyperactivity, Brain Mapping, Central Nervous System Stimulants, Child, Dextroamphetamine, Dose-Response Relationship, Radiation, Electroencephalography, Event-Related Potentials, P300, Female, Humans, Male, Methylphenidate, Neuropsychological Tests, Photic Stimulation, Spectrum Analysis.
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Does event-related wave activity in the EEG provide new marker of ADHD? Context: This study examines the utility of new measures of event-related spatio-temporal waves in the EEG as a marker of ADHD, previously shown to be closely related to the P3 ERP in an adult sample. Wave activity in the EEG was assessed during both an auditory Oddball and a visual continuous performance task (CPT) for an ADHD group ranging in age from 6 to 18 years and comprising mostly Combined and Inattentive subtypes, and for an age and gender matched control group. The ADHD subjects had less wave activity at low frequencies ( approximately 1 Hz) during both tasks. For auditory Oddball targets, this effect was shown to be related to smaller P3 ERP amplitudes. During CPT, the approximately 1 Hz wave activity in the ADHD subjects was inversely related to clinical and behavioral measures of hyperactivity and impulsivity. CPT wave activity at approximately 1 Hz was seen to "normalise" following treatment with stimulant medication.
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The results identify a deficit in low frequency wave activity as a new marker for ADHD associated with levels of hyperactivity and impulsivity. Final Decision: yes