system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which antibodies in mother with SLE is responsible for congenital heart disease in child-
assistant
The correct answer is  Most sensitive → Antinuclear antibody (ANA)
Most specific → Anti-double stranded antibody and the antibody against Smith (Sm)
Associated with neonatal lupus and congenital heart block → Anti Ro, Anti LA antibody
Associated with lupus psychosis → Anti P antibody