system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 35-year-old woman comes to the physician because of a 3-month history of worsening fatigue. She has difficulty concentrating at work despite sleeping well most nights. Three years ago, she was diagnosed with Crohn disease. She has about 7 non-bloody, mildly painful bowel movements daily. Her current medications include 5-aminosalicylic acid and topical budesonide. She does not smoke or drink alcohol. She appears pale. Her temperature is 37.9°C (100.2°F), pulse is 92/min, and blood pressure is 110/65 mmHg. The abdomen is diffusely tender to palpation, with no guarding. Laboratory results show:
Hemoglobin 10.5 g/dL
Mean corpuscular volume 83 μm3
Reticulocytes 0.2 %
Platelets 189,000/mm3
Serum
Iron 21 μg/dL
Total iron binding capacity 176 μg/dL (N=240–450)
A blood smear shows anisocytosis. Which of the following is the most appropriate next step in treatment?"
assistant
Oral prednisone therapy