system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Organisms involved in pit and fissure caries:
assistant
The correct answer is  Pit & fissure caries in initiated by a wide variety of organisms like S. mutans, Lactobacillus and Actinomyces species as they colonize in these retentive areas. However, only S.mutans (very significantly) & S. salivarius (by chance) have been proved to colonise smooth surfaces.