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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Hemolytic crisis in hereditary spherocytosis is precipitated by
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The correct answer is  Ans. (a) Parvovirus B19 infection(Ref: Harrison 18th/pg 1478)Aplastic/hypoplastic crises resulting from parvovirus B19 infection may occur in Hereditary spherocytosis just as is seen in individuals with other chronic hemolytic disorders.Parvovirus B19 selectively infects erythroid precursors and inhibits their growth.Erythropoietic arrest leads to a sudden decrease in hemoglobin concentration and reticulocytopenia.