system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 64-year-old man comes to the emergency department complaining of fatigue and abdominal distension. He has a remote history of intravenous drug use. Vital signs include a normal temperature, blood pressure of 120/80 mm Hg, and a pulse of 75/min. Physical examination reveals jaundice and a firm liver. Abdominal ultrasonography shows liver surface nodularity, moderate splenomegaly, and increased diameter of the portal vein. Complete blood count of the patient is shown:
Hemoglobin 14 g/dL
Mean corpuscular volume 90/μm3
Mean corpuscular hemoglobin 30 pg/cell
Mean corpuscular hemoglobin concentration 34%
Leukocyte count 7,000/mm3
Platelet count 50,000/mm3
Which of the following best represents the mechanism of low platelet count in this patient?
assistant
Platelet sequestration