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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 77-year-old man with a mass in the lung develops asymptomatic hyponatremia. His JVP is 4 cm, heart sounds are normal, and the lungs are clear. The urine sodium is 64 mEq/L and osmolality 550 mOsm/kg. Which of the following is the most likely diagnosis?
assistant
The correct answer is  The urine osmolality in patients with SIADH need not be hypertonic to plasma, but only inappropriately high compared with serum. The major characteristics of SIADH include hyponatremia, volume expansion without edema, natriuresis, hypouricemia, and normal or reduced serum creatinine level, with normal thyroid and adrenal function.