system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following factors causes endometrial hyperplasia?
assistant
The correct answer is  Most cases of endometrial hyperplasia result from high levels of estrogens, combined with insufficient levels of the progesterone-like hormones. This may occur in conditions including obesity, polycystic ovary syndrome, estrogen producing tumours (e.g. granulosa cell tumour) and ceain formulations of estrogen replacement therapy. Endometrial hyperplasia is a significant risk factor for the development or even co-existence of endometrial cancer. Hyper estrogenic state is associated with marked endothelial hyperplasia which regress with progestins.