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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which thyroid carcinoma has amyloid deposition?
assistant
The correct answer is  Medullary carcinomas of thyroid are neuroendocrine tumours derived from the parafollicular cells or C cells. Microscopically acellular amyloid deposits derived from calcitonin polypeptides are present in the stroma in many cases .Calcitonin is readily demonstrable within the cytoplasm of tumour cells as well as in stromal amyloid by immunohistochemical methods. Ref: Robbins and cotrans 9e Pg 1099