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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
All of the following are true regarding progressive multifocal leukoencephalopathy except
assistant
The correct answer is  . *Progressive multi focal leukoencephalopathy characterised by cytological alternations in both astrocytes and oligodendrocytes . *Oligodendrocytes are enlarged ,densely staining nuclei that contain viral inclusions formed by crystallinearrays of JC virus paicles *Almost all patients will have underlying immunocompromissive disorders ,most common associated condition is AIDS(80%), hematological malignancy(13%), transplant recipient(5%) and chronic inflammatory disease(2%). Ref Harrison20th edition pg 2456