system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following anticancer drugs can cause a hypercoagulable state
assistant
The correct answer is  L-asparginase causes the breakdown of aspargine and thus interferes with protein synthesis. It can inhibit the pro­duction of clotting factors (responsible for cerebral hemorrhage) as well as anti-clotting proteins (can lead to cortical vein thrombosis and other hypercoagulable states).