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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Case-Control Studies, Endothelium, Vascular, Erectile Dysfunction, Humans, Impotence, Vasculogenic, Male, Smoking, Vasodilation.
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Does [ Smoking impair endothelial function in ED patients ]? Context: To determine whether smoking affects the endothelial function of young ED patients with no cardiovascular disease. This study included 69 ED patients (21 smokers and 48 non-smokers) and 16 age-matched normal healthy controls. All underwent measurement of brachial artery flow-mediated vasodilation (FMD) and examinations of blood pressure, cholesterol, triglycerides and glucose. Brachial artery FMD was remarkably decreased in the ED patients, even more significantly in the smokers ([6.0 +/- 0.8]%) than in the non-smokers ([9.7 +/- 2.5]%) (P < 0.05), as compared with that in the normal healthy controls ([14.0 +/- 2. 5]%, P < 0.05).
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Endothelial function is impaired in ED patients, and is further damaged by smoking. Final Decision: yes