system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A patient presents with a wound on his leg. It heals six weeks later. Which of the following mediators is involved in promoting wound healing?
assistant
The correct answer is  TGF b (Transforming growth factor b) was responsible for the wound healing. It inhibits T- and B-cell proliferation. It acts as a growth factor for fibroblasts and also promotes class switching of B cells to IgA. TGF b is produced by T and B cells. IL-10 is also involved in wound healing and suppression of inflammation. IFN a inhibits viral replication, activate NK cells, and regulates the activity of macrophages and T cells. TNF a is involved in tumour cytotoxicity, phagocytic cell activation, antiviral and antiparasitic effects. it is an acute phase protien. INF b has antiviral activity. Reference: Ananthanarayan and Paniker&;s Textbook of Microbiology Tenth edition