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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Adult, Aged, Aged, 80 and over, Brain Infarction, Cognition, Cognition Disorders, Female, Humans, Leukoaraiosis, Magnetic Resonance Imaging, Male, Middle Aged, Neuropsychological Tests, Risk Factors, Severity of Illness Index, Stroke.
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Does cognitive performance after lacunar stroke correlate with leukoaraiosis severity? Context: This study investigates the effect of leukoaraiosis on patients presenting with cognitive impairment after lacunar stroke. Fourty-six patients with cognitive impairment and newly discovered lacunar stroke detected by brain magnetic resonance imaging underwent neuropsychological testing. Patients with both lacunar infarct and leukoaraiosis performed less well on cognitive measures, compared to those with lacunar infarcts alone. Additionally, leukoaraiosis severity inversely correlated with cognitive performance.
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In patients with lacunar stroke, presence of leukoaraiosis is associated with worse performance in multiple cognitive domains. These findings suggest lacunar infarcts plus leukoaraiosis is a common etiology for vascular dementia. Final Decision: yes