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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Which one of the following biochemical parameters is the most sensitive to detect open spina
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The correct answer is  Ans. is c i.e. Amniotic fluid acetyl cholinesterase Spina Bifida, anencephaly and encephalocele are collectively included under neural tube defect. As I have already explained in answer 3, amniotic fluid cholinesterase level is elevated in most cases of neural tube defects and has got better diagnostic value than AFP. Extra Edge : Ultrasonographic signs indicating Spina bifida. Small biparietal diameter. Ventriculomegaly. Frontal bone scalloping (the so called lemon sign).deg Elongation and downward displacement of the cerebellum (the so called banana sign).deg Effacement or obliteration of the cisterna magna.