system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A hypeensive patient Sattu already receiving a drug 'X' to control his BP was prescribed a tricyclic antidepressant. This resulted in the abolition of the antihypeensive action of 'X'. Which of the following drug can be 'X'?
assistant
The correct answer is  (Ref: KDT 6/e p444) TCAs abolish the antihypeensive effect of guanethidine and Clonidine by inhibiting their transpo into the adrenergic neurons.