system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: METHODS, RESULTS, DISCUSSION. Meshes: Anti-Bacterial Agents, Antibiotic Prophylaxis, Arthroplasty, Replacement, Hip, Cephalosporins, Confidence Intervals, Decision Support Techniques, Drug Therapy, Combination, Glycopeptides, Humans, Length of Stay, Methicillin-Resistant Staphylococcus aureus, Models, Economic, Odds Ratio, Quality-Adjusted Life Years, Staphylococcal Infections, Surgical Wound Infection, United Kingdom, Vancomycin.
user
An economic model for the prevention of MRSA infections after surgery: non-glycopeptide or glycopeptide antibiotic prophylaxis? Context: An indicative model was designed to explore the cost-effectiveness of vancomycin, cephalosporin or a combination, in patients undergoing primary hip arthroplasty. If the MRSA infection rate is equal to or above 0.25% and the rate of other infections with cephalosporin prophylaxis is equal to or above 0.2%, use of the combination antibiotic prophylaxis is optimal. Modelling the cost-effectiveness of interventions for MRSA prevention is complex due to uncertainty around resistance and effectiveness of glycopeptides.
assistant
The indicative model provides a framework for evaluation. More work is needed to understand the impact of antibiotic resistance over time in these currently effective antibiotics.