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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: African Continental Ancestry Group, Alleles, Asian Continental Ancestry Group, Base Sequence, European Continental Ancestry Group, Female, Forensic Medicine, Gene Frequency, Genetic Variation, Humans, Locus Control Region, Male, Microsatellite Repeats, Molecular Sequence Data, Nucleotides, Oceanic Ancestry Group, Polymerase Chain Reaction, Saliva, Sensitivity and Specificity, Tandem Repeat Sequences.
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Does pentanucleotide short tandem repeat locus DXYS156 display different patterns of variations in human populations? Context: To establish a database for the pentameric short tandem repeat locus DXYS156 from worldwide populations for routine genotyping in forensic identity testing and evolutionary biology. Using polymerase chain reaction with a newly designed primer pair, we analyzed 1,408 male and female samples from 28 populations representing four major geographic groups. We observed 11 different alleles, which we sequenced and used to construct an allelic ladder.
assistant
DXYS156 displays a contrasting pattern of X-linked and Y-linked variation among geographic regions, and between X and Y chromosomes. This complex allele distribution may be forensically useful for the ethnic differentiation of unknown stains. Final Decision: yes