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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, RESULTS. Meshes: .
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Does imidacloprid inhibit IgE-mediated RBL-2H3 cell degranulation and passive cutaneous anaphylaxis? Context: Imidacloprid has been commonly used as a pesticide for crop protection and acts as nicotinic acetylcholine receptor agonists. Little information about the relationship between imidacloprid and allergy is available. This study aims to examine the effects of imidacoprid on IgE-mediated mast cell activation. The rat basophilic leukemia cell line RBL-2H3 (RBL-2H3 cells) were treated with 10 It was shown that imidacoprid suppressed the production of histamine, β-hexosaminidase, leukotriene C4, interleukin-6, tumor necrosis factor-α, and Ca
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It is the first time to show that imidacloprid suppressed the activation of RBL-2H3 cells. Final Decision: yes