system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following statements is TRUE regarding termination of action of a drug?
assistant
The correct answer is  * Action of a drug can be terminated either by hepatic metabolism or by renal excretion. Other pathways like excretion in sweat or saliva plays minor roles. * Most of the drugs are inactivated by metabolism. However, some drugs may be activated from inactive form (prodrugs) and others may produce active metabolites. * Some drugs may act away from blood e.g. digoxin leaves bloodstream and enters the hea to produce its action.