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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, RESULTS. Meshes: Adolescent, Adult, Cross-Sectional Studies, Female, Herpes Genitalis, Herpesvirus 2, Human, Humans, Middle Aged, Risk Factors, Seroepidemiologic Studies, Sexually Transmitted Diseases, Tanzania, Urban Health, Women's Health.
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Does seroprevalence and correlate of herpes simplex virus type 2 among urban Tanzanian women? Context: Data on herpes simplex virus type 2 (HSV-2) among women in the general population of developing countries are limited. The goal of the study was to determine the seroprevalence of HSV-2 and to identify clinical, demographic, and behavioral correlates among women attending primary health care clinics. This was a cross-sectional survey of 382 randomly chosen women aged 15 to 49 years. The seroprevalence of HSV-2 was 39%. Only 2% had a history of genital herpes. HSV-2 was associated with antibody to HIV-1 (OR=2.3 [CI, 1.1-4.7]), syphilis (OR=4.7 [CI, 1.4-4.7]), and genital ulcers (OR=9.7 [CI 2.5-36.9]). Age, sexual debut, number of sex partners, and history of spontaneous abortion were found to be significantly associated with HSV-2. Eighty-two percent of the women with genital ulcers were HSV-2-seropositive, while syphilis accounted for 6% of cases. HSV-2 may thus be the most common cause of genital ulcers in this population.
assistant
In view of the high HSV-2 seroprevalence and its association with HIV-1 and genital ulcers, integration of HSV-2 therapeutic management in STD syndromic algorithms is recommended. Counseling on symptom recognition, asymptomatic shedding, and preventive measures is needed. Final Decision: yes