system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adipokines, Aged, Albuminuria, Biomarkers, Case-Control Studies, Chitinase-3-Like Protein 1, Diabetes Mellitus, Type 2, Diabetic Nephropathies, Female, Hexosaminidases, Humans, Lectins, Male, Middle Aged.
user
Are proteins from the 18 glycosyl hydrolase family associated with kidney dysfunction in patients with diabetes type 2? Context: To investigate chitotriosidase (CHIT1) activity and chitinase-3-like protein 1 (YKL-40) concentration in plasma of type 2 diabetic patients and evaluate their relationship with kidney dysfunction. 94 diabetic subjects and 33 controls were enrolled in the study. Plasma CHIT1 activity and YKL-40 concentration were measured along with routine laboratory parameters. Levels of CHIT1 and YKL-40 in plasma of type 2 diabetic patients increased progressively with the degree of albuminuria. CHIT1 discriminated normoalbuminuric subjects from those with abnormal albuminuria better than YKL-40.
assistant
CHIT1represent a supportive biomarker connected with development of diabetic vascular complications, especially kidney dysfunction. Final Decision: yes