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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: UNLABELLED, RESULTS. Meshes: Adult, Aged, Blood Flow Velocity, Blood Pressure, Cardiovascular Diseases, Carotid Arteries, Diet, Double-Blind Method, Elasticity, Female, Follow-Up Studies, Humans, Lipids, Male, Middle Aged, Reference Values, Risk Factors, Surveys and Questionnaires, Ultrasonography, Doppler, Vascular Resistance, Vitamin E.
user
Does vitamin E improve arterial compliance in middle-aged men and women? Context: Diminished arterial compliance, or loss of elasticity in large arteries, is an emerging cardiovascular risk factor with a reversible component that includes improved endothelial function. Vitamin E, which may reduce cardiovascular risk, can lower vascular resistance. Twenty-eight middle-aged men and women were randomized through a double-blind design to 8 weeks of supplemental vitamin E (400 IU daily) or placebo. Compliance was determined non-invasively from simultaneous measurements of aortic flow and carotid pressure at baseline and after 4 and 8 weeks. arterial compliance increased by 37% at 4 weeks and by 44% at 8 weeks (P = 0.01) only in the vitamin E group and was independent of an effect on arterial pressure. A rise was seen in 12/14 subjects. There was no significant change with placebo (+ 8%).
assistant
short-term vitamin E supplementation improves arterial compliance. Final Decision: yes