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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Activation of which of the following hormone's receptors produces E.Coli induced diarrhoea?
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The correct answer is  Guanylin is a gastrointestinal polypeptide that binds to guanylyl cyclase. It is secreted by cells of the intestinal mucosa. Stimulation of guanylyl cyclase increases the concentration of intracellular cyclic 3',5'-guanosine monophosphate (cGMP), and this in turn causes increased secretion of Cl- into the intestinal lumen. The heat-stable enterotoxin of ceain diarrhea-producing strains of Escherichia coli has a structure very similar to guanylin and activates guanylin receptors in the intestine.