system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, STUDY DESIGN, RESULTS. Meshes: Adrenergic beta-Agonists, Bronchopulmonary Dysplasia, Cohort Studies, Female, Fetal Membranes, Premature Rupture, Humans, Incidence, Indomethacin, Infant, Low Birth Weight, Infant, Newborn, Labor, Obstetric, Logistic Models, Pregnancy, Pregnancy Outcome, Respiration, Respiratory Distress Syndrome, Newborn, Retrospective Studies, Ritodrine, Tocolytic Agents.
user
The addition of indomethacin to betamimetics for tocolysis: any benefit for the neonate? Context: To study the influence on the neonate of indomethacin administered to the mother as an additional tocolytic. The neonatal outcome in 76 closely matched low birth weight infants was compared retrospectively: those whose mothers received indomethacin together with betamimetics formed the study group, those whose mothers received only betamimetics formed the control group. There was an increased incidence of respiratory distress syndrome (RDS) in the study group (97% versus 45%; P<0.001), an increased need for surfactant use (68% versus 26%; P<0.001) and increased ventilatory support, and an increased incidence of bronchopulmonary dysplasia (BPD) (47% versus 24%; P=0.03). Gestation could not be prolonged significantly by the addition of indomethacin.
assistant
Indomethacin as an additional tocolytic agent was associated with an increased incidence of RDS, surfactant use and BPD but did not significantly prolong gestation.