system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Causes for less bioavailability -
assistant
The correct answer is  Ans. is 'a' i.e., High first pass metabolism o Causes for less bioavailability. Incomplete absorption o High first pass metabolism. About other options Increased absorption increases bioavailability. o I.V. administration has 100% bioavailahi I ity. High lipid solubility causes more absorption and better bioavailability.