system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Hepatitis with cholestatic jaundice occurs most frequently as an adverse reaction to the following preparation of erythromycin:
assistant
The correct answer is  Erythromycin estolate is responsible for cholestatic jaundice. It stas after 2-3 weeks of staing treatment. Symptoms include nausea, vomiting and cramping pain in abdomen. Risk of this adverse effect increases significantly in pregnancy. Therefore, erythromycin estolate is contra-indicated in pregnancy.