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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Chorionic Gonadotropin, Dendritic Cells, Estradiol, Female, Flow Cytometry, Humans, Postpartum Period, Pregnancy, Pregnancy Trimesters, Progesterone, Young Adult.
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Do decline of Plasmacytoid Dendritic Cells and Their Subsets in Normal Pregnancy Are Related with Hormones? Context: To analyze the frequency of plasmacytoid dendritic cells (pDCs) in pregnancy, especially their subsets, by flow cytometry in each trimester and in the postpartum period. Peripheral blood was collected from pregnant women in each trimester and from non-pregnant women. Serum hormones were detected by ELISA, while pDCs and their subsets were detected by flow cytometer. Then correlation between them was further analyzed. Both pDCs and their subsets declined as pregnancy progressed. Further experiments indicate that estradiol and progesterone are significantly negatively correlated with this change.
assistant
Our findings increase the knowledge of pDC subsets in healthy pregnant conditions. Final Decision: yes