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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, RESULTS. Meshes: Administration, Oral, Adult, Arthrodermataceae, Cohort Studies, DNA, Fungal, Drug Therapy, Combination, Female, Fusarium, Humans, Itraconazole, Male, Middle Aged, Naphthalenes, Onychomycosis, Polymerase Chain Reaction, Retrospective Studies, Severity of Illness Index, Terbinafine, Treatment Failure, Trichophyton.
user
Appear oral terbinafine and itraconazole treatments against dermatophytes to favor the establishment of Fusarium spp . in nail? Context: Fusarium onychomycoses are weakly responsive or unresponsive to standard onychomycosis treatments with oral terbinafine and itraconazole. To examine whether the use of terbinafine and itraconazole, which are highly effective in fighting Trichophyton onychomycoses, could be a cause of the high incidence of Fusarium nail infections. Polymerase chain reaction methods were used to detect both Fusarium spp. and Trichophyton spp. in nails of patients who had either received treatment previously or not. No significant microbiological differences were found between treated and untreated patients. In 24 of 79 cases (30%), Fusarium spp. was detected in samples of patients having had no previous antifungal therapy and when Trichophyton spp. grew in culture.
assistant
Oral terbinafine and itraconazole treatments do not appear to favor the establishment of Fusarium spp. in onychomycosis. Final Decision: no