system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Among the following true about linezolid except
assistant
The correct answer is  OXAZOLIDINONE Linezolid:- Mech of action:- Linezolid inhibits bacterial protein synthesis by acting at an early step and a site different from that of other AMAs. It binds to the 23S fraction (P site) of the 50S ribosome and interferes with formation of the ternary N-formylmethionine- tRNA (tRNAfMet) -70S initiation complex. Binding of linezolid distos the tRNA binding site overlapping both 50S and 30S ribosomal subunits and stops protein synthesis before it stas. uses:- Used in treatment of resistant gram-positive coccal (aerobic and anaerobic) and bacillary infections. It is active against MRSA and some VRSA, VRE, penicillin-resistant Strep. pyogenes, Strep. viridans and Strep. pneumoniae, M. tuberculosis, Corynebacterium, Listeria, Clostridia and Bact. fragilis. It is primarily bacteriostatic, but can exe cidal action against some strepto-cocci, pneumococci and B. fragilis. Gram- negative bacteria are not affected. Ref:- kd tripathi; pg num:-758