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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following is associated with a sudden decrease in serum calcium levels?
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The correct answer is  Manifestations of acute hypocalcemia includes increased neuromuscular excitability and cardiovascular effects of a decrease in ionized calcium. Nerves exposed to low ionized calcium, levels shows decreased threshold for excitation, repetitive responses to a single stimulus and in extreme cases continuous activity. Increased neuromuscular excitability manifest as paresthesias and tetany. In severe cases laryngeal spasm, seizures and death can occur. Ref: Poh Pathophysiology: Concepts of Altered Health States By Ruth A. Hannon, Page 762