system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: UNLABELLED. Meshes: Animals, Antineoplastic Agents, Atrial Natriuretic Factor, Blotting, Western, Cell Line, Tumor, Cell Proliferation, DNA, Neoplasm, Dose-Response Relationship, Drug, Elapidae, Glioblastoma, Humans, Myocardium, Peptide Fragments, Peptides, Protein Precursors, Receptors, Atrial Natriuretic Factor, Time Factors.
user
Do four cardiac hormones eliminate 4-fold more human glioblastoma cells than the green mamba snake peptide? Context: Within 24h four cardiac hormones, i.e., vessel dilator, kaliuretic peptide, atrial natriuretic peptide, and long acting natriuretic peptide decrease the number of human glioblastoma cells 75%, 68%, 67%, and 65% while Dendroaspis (green mamba) peptide caused a 17% decrease when each were utilized at 100 microM. The four cardiac hormones decreased DNA synthesis 65-87% and increased cyclic GMP 1.3- to 3.8-fold in the glioblastoma cells. Natriuretic peptide receptors (NPR)-A and -C were present.
assistant
four cardiac hormones eliminate up to 75% of glioblastoma cells via cyclic GMP-mediated up to 87% decrease in DNA synthesis. Final Decision: yes