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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Adult, Anger, Antisocial Personality Disorder, Benzopyrans, Cerebral Cortex, Female, Humans, Magnetic Resonance Imaging, Male, Morpholines, Piperazines, Positron-Emission Tomography, Protein Binding, Psychiatric Status Rating Scales, Receptor, Serotonin, 5-HT1B, Serotonin Receptor Agonists, Violence, Young Adult.
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Does serotonin 1B Receptor Binding be Associated With Trait Anger and Level of Psychopathy in Violent Offenders? Context: The involvement of serotonin in aggression has traditionally been attributed to impaired prefrontal serotonergic inhibitory control of emotional reactions to provocations in antisocial individuals. However, it is unclear which specific serotonergic receptors are involved in the effects. A large body of preclinical research supports a specific role of serotonin 1B receptors (5-HT Nineteen incarcerated violent offenders and 24 healthy control nonoffenders were included and examined with positron emission tomography, using the radioligand [ Group status significantly moderated the association between striatal 5-HT
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Our data demonstrate for the first time in humans a specific involvement of 5-HT Final Decision: yes