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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Cystic Fibrosis, Environmental Exposure, Female, Follow-Up Studies, Humans, Lung, Male, Morbidity, Pseudomonas Infections, Pseudomonas aeruginosa, Retrospective Studies, Sewage, United States.
user
Is pseudomonas aeruginosa in CF and non-CF homes found predominantly in drains? Context: For patients with cystic fibrosis (CF) Pseudomonas aeruginosa infection is a major contributor to progressive lung disease. While colonizing strains are thought to be primarily environmental, which environments are important in lung colonization is unclear. We took 11,674 samples from a broad range of sites over 3-8 visits to homes with (7) and without (8) CF patients. Twenty-eight percent of sampled drains yielded P. aeruginosa at least once, and a general mixed linear model estimated that 6.3% of samples from drains yield P. aeruginosa. This is more than eight times the estimated recovery from any other type of household environment.
assistant
These findings implicate drains as important potential sources of P. aeruginosa infection. They suggest that maximizing P. aeruginosa control efforts for drains would reduce exposure with minimal extra burden to CF patients and families. Final Decision: yes