system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE. Meshes: Angiopoietin-1, Angiopoietin-2, Animals, Chorionic Gonadotropin, Female, Follicle Stimulating Hormone, Macaca mulatta, Ovarian Follicle, Oxygen, Vascular Endothelial Growth Factor A.
user
Is vascular endothelial growth factor and angiopoietin production by primate follicles during culture a function of growth rate , gonadotrophin exposure and oxygen milieu? Context: What is the time course of production of vascular endothelial growth factor-A (VEGF-A), angiopoietin (ANGPT)-1 and ANGPT-2 by primate follicles during encapsulated three-dimensional culture, and what conditions affect their production?
assistant
Primate follicles produce VEGF-A and ANGPT-2 in vitro, particularly after developing to the antral stage, with VEGF production influenced by FSH concentration and O(2) tension. Final Decision: yes