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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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What is the mode of inheritance of Hereditary spherocytosis?
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The correct answer is  - Hereditary spherocytosis is inherited in an Autosomal dominant pattern. - Results from instability of spectrin & ankyrin which are major skeletal membrane proteins. - Degree of protein deficiency correlates with degree of hemolysis. - Demonstrated by Increase in osmotic fragility after 24hrs incubation of blood at 37oC.