system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following treatment for menorrhagia is not suppoed by evidence?
assistant
The correct answer is  Ethamsylate is known to reduce capillary fragility. Hence it is not effective for uterine bleeding which is more due to the vasodilator prostaglandins. Antiprostaglandins are used since NSAIDs reduce prostaglandin levels by inhibiting cyclooxygenase and decreasing the ratio of prostacyclin to thromboxane. Prostaglandin E2 synthesis Prostaglandin E binding sites are reduced as well.