system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 42-year-old woman comes to the physician because of a 2-month history of generalized itching and worsening fatigue. There is no personal or family history of serious illness. She takes eye drops for dry eyes. She occasionally takes acetaminophen for recurrent headaches. She drinks one alcoholic beverage daily. Vital signs are within normal limits. Examination shows jaundice and a nontender abdomen. The liver is palpated 3 cm below the right costal margin and the spleen is palpated 2 cm below the left costal margin. Laboratory studies show:
Hemoglobin 15.3 g/dL
Leukocyte count 8,400/mm3
Prothrombin time 13 seconds
Serum
Bilirubin
Total 3.5 mg/dL
Direct 2.4 mg/dL
Alkaline phosphatase 396 U/L
Aspartate aminotransferase (AST, GOT) 79 U/L
Alanine aminotransferase (ALT, GPT) 73 U/L
A liver biopsy specimen shows inflammation and destruction of small- and medium-sized intrahepatic bile ducts. Magnetic resonance cholangiopancreatography (MRCP) shows multiple small stones within the gallbladder and a normal appearance of extrahepatic bile ducts. Which of the following is the most appropriate next step in management?"
assistant
Dual-energy x-ray absorptiometry