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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Mutation in Marfan's syndrome is?
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The correct answer is  Robbins and Cotran pathologic basis of disease South Asia edition. * Marfan's syndrome results from an inherited defect in an extracellular glycoprotein called fibrillin 1 by loss of structural suppo in microfibril rich connective tissues and excessive activation of TGF- beta signally Ref Robbins 9/e pg252