system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 2-month-old Middle Eastern female infant from a consanguinous marriage presents with seizures, anorexia, failure to thrive, developmental delay, and vomiting and fatigue after eating. Blood work demonstrated levels of methylmalonic acid nearly 500 times normal levels. A carbon-14 propionate incorporation assay was performed on the fibroblasts of the patient and compared to a healthy, normal individual. Little to none of the radiolabeled carbons of the propionate appeared in any of the intermediates of the Krebs cycle. Which of the following reactions is not taking place in this individual?
assistant
Methylmalonyl-CoA --> Succinyl-CoA