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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, RESULTS. Meshes: Adolescent, Adult, Anti-Inflammatory Agents, Child, Child, Preschool, Dermatitis, Atopic, Double-Blind Method, Female, Glucocorticoids, Humans, Male, Pharmaceutical Vehicles, Phytotherapy, Placebos, Treatment Outcome, Triamcinolone Acetonide.
user
Does low-dose triamcinolone acetonide in the phytocosmetic lichtena reduce inflammation in mild to moderate atopic dermatitis? Context: Previously, we reported the efficacy of Lichtena--a phytocosmetic cream product--in atopic dermatitis (AD). Later, fraudulent triamcinolone acetonide (TACA) was detected at low doses (16-40 microg/g) in Lichtena. This suggested that TACA may be effective at much lower concentrations than used in commercial products (1,000 microg/g). To investigate the efficacy in AD of low-dose TACA in Lichtena compared to plain Lichtena. Fourteen patients presenting symmetrical lesions of AD were treated for 1 month with Lichtena plus 25 microg/g TACA (= verum) and plain Lichtena (= placebo). The severity of the lesions was assessed by the Severity Scoring of Atopic Dermatitis (SCORAD) on days 0 (= baseline), 7, 14 and 28. Already after 1 week of treatment, significant SCORAD differences to baseline were observed comparing verum- and placebo-treated areas. No improvement was observed using plain Lichtena.
assistant
TACA displayed a significant improvement of AD at doses up to 40 times lower than in commercial products. Final Decision: yes