system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
5-methyl cytosine mutation of DNA (DNA methylation) leads to:
assistant
The correct answer is  A i.e. Deamination to thiamine; B i.e. DNA repair > C i.e. Methylation protects the host DNA from cleavage by its own restriction enzymeDeamination of cytosine forms uracil and deamination of 5 methyl cytosine forms thymine. TDG & MBD4 DNA uracil glycosylase remove either U or T residues paired with G, generated by deamination.DNA methylation of adenine at 5' GATC repair mismatched base pairs. And methylated parental (template) strand is protected from cleavage / digestion by its own restriction enzyme.