system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Cyclosporine in nephrotic syndrome acts by -
assistant
The correct answer is  Ans. is 'a' i.e., Inhibiting calcineurin Stroid dependent nephrotic syndromeo The treatment options for steroid resistant nephrotic syndrome are:i) Calcineurin inhibitors (cyclosporine, Tacrolimus)ii) IV or oral cyclophosphamideiii) Levamisoliv) Mycophenolatev) Pulse corticosteroido All above immunosuppressants are used along with corticosteriods (Prednisolone or methylprednisolone).o Cyclosporine and cyclophosphamide are most commonly used.o Despite these options, there is lack of consensus on first line appropriate therapy for steroid resistant nephrotic syndrome.