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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, RESULTS. Meshes: Adult, Aged, Aged, 80 and over, Angina Pectoris, Biomarkers, Blood Proteins, C-Reactive Protein, Case-Control Studies, Coronary Artery Disease, Female, Humans, Intercellular Adhesion Molecule-1, Male, Middle Aged, Myocardial Infarction, Retrospective Studies, Vascular Cell Adhesion Molecule-1, alpha-2-HS-Glycoprotein.
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Are decreased serum fetuin-A levels associated with coronary artery diseases? Context: To analyze Fetuin-A levels and soluble cellular adhesion molecules in patients with acute coronary syndrome. Serum Fetuin-A and intercellular adhesion molecule-1 (sICAM-1), vascular cellular adhesion molecule-1 (sVCAM-1) levels were examined in 127 patients who presented with chest pain. These patients were classified in three groups: stable angina (SA, n=51), myocardial infarction (MI, n=34) and non-cardiac group (n=42). Logarithmic transformations were made for Fetuin-A levels. Log-Fetuin-A levels were higher in non-cardiac subjects compared to MI and SA patients (p<0.05). Patients with SA showed lower levels than controls but higher levels as compared to MI patients. After controlling for age and gender, levels of sVCAM-1 and sICAM-1 in patients with coronary atherosclerosis were not different from those in non-cardiac subjects.
assistant
Serum levels of soluble VCAM-1, ICAM-1 were not related to coronary artery disease (CAD), but fetuin-A levels seems to be decreased in SA and MI patients. Low fetuin-A may play a role in the pathophysiology of CAD. Final Decision: yes