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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, METHODS, METHODS, METHODS, RESULTS. Meshes: Accident Prevention, Accidental Falls, Aged, Depression, Female, Finland, Humans, Incidence, Male, Risk Factors, Statistics, Nonparametric, Treatment Outcome.
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Does effect of a risk-based multifactorial fall prevention program on the incidence of fall? Context: To evaluate the effects of a multifactorial fall prevention program on falls and to identify the subgroups that benefit the most. Randomized controlled trial. Community-dwelling subjects who had fallen at least once during the previous 12 months. Five hundred ninety-one subjects randomized into intervention (IG) (n=293) and control (CG) (n=298) groups. A multifactorial 12-month fall prevention program. Incidence of falls. The intervention did not reduce the incidence of falls overall (incidence rate ratio (IRR) for IG vs CG=0.92, 95% confidence interval (CI)=0.72-1.19). In subgroup analyses, significant interactions between subgroups and groups (IG and CG) were found for depressive symptoms (P=.006), number of falls during the previous 12 months (P=.003), and self-perceived risk of falling (P=.045). The incidence of falls decreased in subjects with a higher number of depressive symptoms (IRR=0.50, 95% CI=0.28-0.88), whereas it increased in those with a lower number of depressive symptoms (IRR=1.20, 95% CI=0.92-1.57). The incidence of falls decreased also in those with at least three previous falls (IRR=0.59, 95% CI=0.38-0.91) compared to those with one or two previous falls (IRR=1.28, 95% CI=0.95-1.72). The intervention was also more effective in subjects with high self-perceived risk of falling (IRR=0.77, 95% CI=0.55-1.06) than in those with low self-perceived risk (IRR=1.28, 95% CI=0.88-1.86).
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The program was not effective in reducing falls in the total sample of community-dwelling subjects with a history of falling, but the incidence of falls decreased in participants with a higher number of depressive symptoms and in those with at least three falls. Final Decision: yes