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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Trastuzumab is directed against
assistant
The correct answer is  Trastuzumab is a humanized monoclonal antibody directed against the extracellular domain of the (human epidermal growth factor receptor -2) HER-2 surface receptor and is effective treatment for HER-2-positive breast cancer Ref: Sabiston 20e, page: 840