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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Hemorrhagic cystitis is caused by :
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The correct answer is  Cyclophosphamide is a prodrug and is activated by hepatic biotransformation to aldophosphamide. One of its degrada­tion products is acrolein that is responsible for hemorrhagic cystitis (its characteristic adverse effect). This adverse effect can be decreased by vigorous hydration and by the use of mercapto ethane sulfonic acid (mesna).