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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: .
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Do cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation? Context: Biomarkers are urgently needed for the critical yet understudied preclinical stage of Alzheimer's disease (AD). CSF collection, [C-11]PiB amyloid imaging, and MRI were acquired in n=104 cognitively healthy adults enriched with risk for sporadic AD. Image-derived cerebral β-amyloid (Aβ) burden, measured concurrently and longitudinally, was regressed on CSF measures of Aβ, neural injury, and inflammation, as well as ratios with Aβ At baseline, Aβ
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These results corroborate previous findings that t-tau/Aβ Final Decision: yes