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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Adolescent, Adult, Amniocentesis, Amniotic Fluid, Biophysical Phenomena, Biophysics, Female, Fetal Monitoring, Gestational Age, Humans, Oligohydramnios, Parity, Pregnancy, Pregnancy, Multiple, Reproducibility of Results, Spectrophotometry, Twins, Ultrasonography, p-Aminohippuric Acid.
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Is low amniotic fluid volume poorly identified in singleton and twin pregnancies using the 2 x 2 cm pocket technique of the biophysical profile? Context: This study was done to determine the accuracy of the 2 x 2 cm pocket identifying low amniotic fluid (AF) volume in singleton and twin pregnancies. The AF volume was evaluated by ultrasonography for the presence of a 2 x 2 cm pocket before amniocentesis. The actual AF volume was then determined by a diazo-dye reaction with subsequent spectrophotometric analysis using paraminohippurate. The AF volume was low in 21 of the 79 singleton pregnancies and normal in 47; hydramnios was present in 11. Among amniotic sacs of the 60 twin pairs, oligohydramnios was found in 33 amniotic sacs. normal AF volume in 80 sacs, and high volume in 7. An AF pocket smaller than 2 x 2 cm was identified in only 3 of the 79 singleton pregnancies and in only 2 of the 120 twin amniotic sacs.
assistant
Judging AF volume on the basis of a 2 x 2 cm pocket misses more than 90% of cases of oligohydramnios in singletons and twins. Final Decision: yes