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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, METHODS, RESULTS. Meshes: Adolescent, Adult, Bifidobacterium, Cholesterol, Cholesterol, HDL, Cholesterol, LDL, Colony Count, Microbial, Female, Humans, Lactobacillus acidophilus, Lipid Metabolism, Lipids, Male, Oligosaccharides, Probiotics, Single-Blind Method, Triglycerides.
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Do probiotic capsules lower plasma lipids in young women and men? Context: To investigate the effect of probiotic capsules on plasma lipids. A randomized, single-blinded, placebo-controlled, parallel-arm trial. Fifty-five normocholesterolemic subjects ages 18-36 (33 premenopausal women and 22 men). Each subject consumed either three probiotic capsules each containing a total of 10(9) colony-forming units Lactobacillus acidophilus and Bifidobacterium longum and 10-15 mg fructo-oligosaccharide or three placebo capsules daily for 2 months (men) or two menstrual cycles (women). Plasma lipids were measured before and following the intervention (during the early follicular phase for women). Plasma concentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and triglyceride were not altered by consumption of probiotic or placebo capsules and were not different between treatment groups following the intervention.
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These results do not support a beneficial effect of Lactobacillus acidophilus strain DDS-1 and Bifidobacterium longum strain UABL-14 on plasma lipids in normocholesterolemic young women and men. Final Decision: no