system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Apgar Score, Cesarean Section, Cohort Studies, Diabetes, Gestational, Female, Humans, Hypertension, Infant, Newborn, Israel, Labor, Induced, Maternal Age, Multivariate Analysis, Parity, Perinatal Mortality, Polyhydramnios, Pregnancy, Pregnancy Complications, Cardiovascular, Pregnancy, Twin, Reproductive Techniques, Assisted, Retrospective Studies.
user
Is gestational diabetes mellitus in twin pregnancies associated with adverse perinatal outcomes? Context: To investigate the influence of gestational diabetes mellitus (GDM) on maternal and neonatal outcomes in twin pregnancies. A retrospective population-based study was conducted, comparing maternal and neonatal outcome in women carrying twins with and without GDM. Deliveries occurred in a tertiary medical center between the years 1988 and 2010. Multivariable analysis was used to control for confounders. The study population included 4,428 twin pregnancies, of these 341 (7.7 %) were complicated with GDM. Twin pregnancies complicated with GDM had higher rates of fertility treatment, chronic hypertension, preeclampsia and cesarean deliveries (CD). Nevertheless, using a multivariable analysis, with CD as the outcome variable, controlling for confounders such as maternal age, fertility treatments and hypertensive disorders, GDM in twins was not found to be an independent risk factor for CD (adjusted OR = 1.8, 95 % CI 0.9-1.4; P = 0.18). Rates of low 5 min Apgar scores (<7) and perinatal mortality were lower among twins with GDM (2.9 % vs. 5.3 %, OR = 0.5, 95 % CI 0.3-0.8 0; P = 0.005 and 2.3 % vs. 4.4 %, OR = 0.5, 95 % CI 0.3-0.8; P = 0.005, respectively).
assistant
In our population, GDM in twin pregnancies was not associated with increased rates of adverse perinatal outcomes. In addition, GDM was not found to be an independent risk factor for CD in twin pregnancies. Final Decision: no