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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Schistocytes in peripheral smear are seen in all except:
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The correct answer is  Schistocyte is fragmented RBC which is seen in any condition where there is micro and macro angiopathic hemolytic anemias. Microangiopathic hemolytic anemia is most commonly seen with DIC, TTP, hemolytic-uremic syndrome (HUS), malignant HTN, SLE, and disseminated cancer. Macroangiopathic schistocyte is seen in patient with prosthetic hea valve. Sickle cell anemia: Blockage of vessels by sickled cells causes pain crises and tissue infarction, paicularly of the marrow and spleen. Red cell membrane damage caused by repeated bouts of sickling results in a moderate to severe hemolytic anemia.