system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, STUDY DESIGN, RESULTS. Meshes: Adult, Aged, Aged, 80 and over, Catheterization, Cough, Female, Humans, Manometry, Middle Aged, Retrospective Studies, Urinary Incontinence, Urodynamics, Uterine Prolapse, Valsalva Maneuver.
user
Does pelvic organ prolapse reduction affect abdominal leak point pressures? Context: To determine if pelvic organ prolapse reduction decreases cystometric leak point pressure. A retrospective review was performed of women with pelvic organ prolapse points Aa, Ba or C>or = -1 cm that leaked with and without vaginal support (barrier testing) during multichannel urodynamic investigation (N=44). An analysis of the mean and difference between leak point pressure (LPP) (vesicle pressure) with and without prolapse reduction was used to determine significance. Among 460 possible study subjects, 15% (71/460) leaked only with and 4% (17/460) only without prolapse reduction. Among the 44 women who leaked both with and without prolapse reduction, prolapse reduction was associated with a mean decrease in LPP of 16.1 cm H2O (95% CI 7.4-24.7, p = 0.0005).
assistant
Reduction of pelvic organ prolapse is associated with a mean decrease in LPP of 16.1 cm H2O.