system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE. Meshes: Animals, Contraception, Contraceptive Agents, Female, Gene Expression Regulation, Indomethacin, Macaca, Macaca fascicularis, Oocytes, Ovarian Follicle, Ovary, Ovulation, Pregnancy, Pregnancy, Animal, RNA, Messenger, Receptors, Prostaglandin E, Time Factors.
user
Does a prostaglandin E2 receptor antagonist prevent pregnancies during a preclinical contraceptive trial with female macaques? Context: Can administration of a prostaglandin (PG) E2 receptor 2 (PTGER2) antagonist prevent pregnancy in adult female monkeys by blocking periovulatory events in the follicle without altering menstrual cyclicity or general health?
assistant
This is the first study to demonstrate that a PTGER2 antagonist can serve as an effective non-hormonal contraceptive in primates. Final Decision: yes