system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 37-year-old man previously treated with monotherapy for latent tuberculosis develops new-onset cough, night sweats and fever. He produces a sputum sample that is positive for acid-fast bacilli. Resistance testing of his isolated bacteria finds a mutation in the DNA-dependent RNA polymerase. To which of the following antibiotics might this patient's infection be resistant?
assistant
Rifampin