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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Adult, Brain, Cognitive Behavioral Therapy, Depressive Disorder, Major, Female, Gray Matter, Gyrus Cinguli, Humans, Magnetic Resonance Imaging, Male, Neuroimaging, Predictive Value of Tests, Sample Size, Treatment Outcome, Young Adult.
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Does anterior cingulate volume predict response to cognitive behavioral therapy in major depressive disorder? Context: Cognitive behavioral therapy (CBT) is widely used to treat major depressive disorder (MDD). Although improved response prediction could facilitate the development of individualized treatment plans, few studies have investigated whether underlying brain structure is related to CBT response in MDD. Ten MDD patients who received individual CBT were studied in this study. We investigated the relationship between the regional gray matter (GM) volume and subsequent responses to CBT using voxel-based morphometry. The degree of improvement in depressive symptoms was positively correlated with GM volume in the caudal portion of the anterior cingulate cortex.
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The sample size was small, and the effects of medication on the results could not be excluded. Final Decision: yes