system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 36-year-old woman is admitted to the hospital because of irritability, nausea, and diarrhea. She has a history of recreational oxycodone use and last took a dose 48 hours ago. Physical examination shows mydriasis, rhinorrhea, and piloerection. A drug is administered that provides an effect similar to oxycodone but does not cause euphoria. Which of the following best explains the difference in effect?
assistant
Lower efficacy