system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Nitrates act by -
assistant
The correct answer is  Ans. is 'b' i.e., Activate/Guanyl/cyclase and increase cGMP Mechanism of action of nitrates:* Organic nitrates are rapidly denitrated enzymatically in the smooth muscle cell to release nitric oxide (NO) which activates cytosolic guanyl cyclase - | cGMP - Vasodilatation.* Veins express greater amount of the enzyme that generates NO from organic nitrates than arteries - Account for the predominant venodilatory effect.