system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following statments about the biodisposition of penicillins and cephalosporins is NOT accurate?
assistant
The correct answer is  (Ref: KDT 6/e p697) Probenecid inhibits renal tubular secretion of penicillins (not reabsorption) Beta lactams eliminated by biliary route are: - Ampicillin - Nafcillin - Ceftriaxone - Cefoperazone Penicillin G has to be given by i.m. route because it is broken down by gastric acid (decreases oral bioavailability).