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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, RESULTS. Meshes: Adolescent, Age Distribution, Cameroon, Child, Child, Preschool, Colorimetry, Congenital Hypothyroidism, Diet, Female, Humans, Iodine, Male, Nutritional Status, Population Surveillance, Prevalence, Risk, Thiocyanates, Young Adult.
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Are youth of west-Cameroon at high risk of developing IDD due to low dietary iodine and high dietary thiocyanate? Context: Hypothyroidism in utero leading to mental retardation is highly prevalent in developing countries where iodine deficiency and thiocyanate overload are combined. To explore prevalence of IDD in Bamougoum, a mountain region of western Cameroon, by studying urinary iodine and thiocyanate excretion levels in children. Bamougoum district in western Cameroon was selected for closer study due to its geographic location predisposing to iodine deficiency disorders (IDD). A comprehensive sampling strategy included 24-h urine samples collected over three days from 120 school-aged children. Urinary iodine and thiocyanate levels were measured by colorimetric methods. Twenty one percent of boys between the ages 3 and 19 were classified as iodine deficient. The prevalence of thiocyanate overload in the same population was found to be 20%.
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Presence of endemic iodine deficiency and excessive thiocyanate in the population indicates that the region is at risk of iodine deficiency disorder. A multifactorial approach that includes improvement of diet, increasing iodine and minimizing goitrogen substances intake, soil and crop improvement and an iodine supplementation program may help alleviate IDD in the affected area studied. Final Decision: yes