system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Selegiline acts by:
assistant
The correct answer is  (Ref: Katzung 14th ed. pg. 499)* After release of DA in synaptic cleft, it is metabolized either by MAO-b or by COMT (catechol-ortho methyl transferase)* In order to prevent this metabolism following drugs can be given, which will enhance DA availability:# MAO-b inhibitor: Selegiline, Rasagiline, safinamide# COMT inhibitor: Entacapone, TolcaponeDrugs stimulating DA receptor:* Ergot Derivative: Bromocriptine, Cabergoline* Non-Ergot: Pramipexole, Ropinirole, Rotigotine (available as transdermal patch)