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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following statements about amoebicides is LEAST accurate?
assistant
The correct answer is  Paromomycin and diloxanide furoate are luminal ameobicides. Paromomycin is an efficacious luminal amoebicide, achieving similar or even better clearing of cysts from stools compared to diloxanidc furoate in asymptomatic cyst passers. It is an aminoglycoside antibiotic which closely resembles neomycin. Metronidazole is the main drug in intestinal ameobiasis. Emetine is a potent and directly acting amoebicide - kills trophozoites but has no effect on cysts. It is a local irrirant and has high systemic toxicity, viz, nausea, vomiting (due to CTZ stimulation and gastric irritation), abdominal cramps, diarrhoea, weakness, stiffness of muscles, myositis, hypotension, ECG changes and myocarditis. Hence it is contraindicated in pregnancy and in patients with cardiac disease.