system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
True about aplastic anemia -
assistant
The correct answer is  In aplastic anemia destruction of hemopoietic stem cells occurs ,it results in reduced reticulocyte count. The bone marrow in aplastic anemia is markedly hypocellular, with greater than 90% of the interabecular space being occupied by fat. The limited cellularity often consists only of lymphocytes and plasma cells. Anemia may cause fatty change in the liver. Thrombocytopenia and granulocytopenia may result in hemorrhages and bacterial infections, respectively. The requirement for transfusions may eventually lead to hemosiderosis. ReferenceExam preparatory manual for UGs - Ramdas nayak page no.-260 Ref Robbins 9/e pg 424