system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A person with radiologically confirmed reflux nephropathy develops nephrotic range proteinuria. Which of the following would be the most likely histological finding in this patient?
assistant
The correct answer is  Focal segmental glomerulosclerosis It is the most common cause of nephrotic syndrome in adults. Sclerosis is seen in only segment of glomerulus. It is associated with HIV infection, reflux nephropathy & definitive association with sickle cell disease. The patient presents with nephrotic range proteinuria too.