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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Management of persistent cases of CSF rhinorrhea is:
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The correct answer is  CSF rhinorrhoea It refers to the drainage of cerebrospinal fluid through the nose. Measures of CSF components such as beta-2 transferrin has been shown to have a high positive predictive value. It has also been noted to be characterized by unilateral discharge. It is a sign of basal skull fracture. Management includes watchful waiting - leaks often stop spontaneously; if this does not occur then neurosurgical closure is necessary to prevent the spread of infection to the meninges.