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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Investigation of choice to diagnosis Hirschsprug's disease is:
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The correct answer is  Ans. is 'c' i.e. Rectal biopsy RepeatYou already know about the features of Hirschsprung's disease seen on contrast enema from the question asked earlierMore about the diagnosis of Hirschsprung's disease -Definitive diagnosis of Hirschsprung's disease is made by Rectal biopsy :It demonstrates following features-Absence of ganglion cells in Meissner's plexus, and myenteric plexusHypertrophy of nerve trunksManometric study - Manometric studies will show a failure of relaxation of internal sphincter following rectal distension.