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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Animals, Carbamide Peroxide, Caseins, Cattle, Colorimetry, Dentin, Drug Antagonism, Drug Combinations, Hydrogen Peroxide, Peroxides, Spectrophotometry, Tooth Bleaching, Tooth Bleaching Agents, Urea.
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Do tooth whitening with hydrogen/carbamide peroxides in association with a CPP-ACP paste at different proportions? Context: Different enhanced peroxide formulations have been developed to overcome mineral loss during tooth whitening. This study investigated the impact on tooth whitening from combining a CPP-ACP paste with home peroxide agents at several proportions. Ninety bovine incisors were randomly allocated into nine groups (n = 10) and exposed to 7.5% hydrogen peroxide (HP), 16% carbamide peroxide (CP), a CPP-ACP paste (Tooth Mousse/MI Paste, GC Corporation, Tokyo, Japan) and blends of HP/CP:MI at three proportions (1:1, 2:1 and 1:2). Tooth whitening was performed for 14 days and its effectiveness was measured by a spectrophotometer utilizing the CIE L*a*b* system (ΔE, ΔL*, Δa* and Δb*). Colour readings were measured at baseline (T0), 7 days of bleaching (T7), 14 days of bleaching (T14) and 7 days after the end of bleaching (T21). Data were analysed by two-way ANOVA for paired averages followed by the Tukey's test and Pearson's correlation at 5%. Although CP produced the greatest colour change (ΔE), all whitening protocols were considered to be effective regardless of the CPP-ACP presence. In general, greater changes in ΔE, ΔL*, Δa* and Δb* were detected at T14, with T21 exhibiting similar results to those at T7. A greater number of strong correlations with ΔE values was found for a* (11/15).
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Within the limitations of this study, the results indicate that the CPP-ACP paste did not affect tooth whitening efficacy. Final Decision: yes