system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Locked in state is associated with ?
assistant
The correct answer is  Ans. is 'b' i.e., Pons Locked in syndrome is caused by an insult to ventral pons (basis pontis). It is characterized by inability to speak and quadriplagia. There is complete paralysis of all voluntary muscles except for the eyes. The lesion essentially interrupts coicobulbars and coicospinal pathways. Somatosensory and ascending neuronal pathways responsible for arousal and wakfullness remain intact.