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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Allergens, Dermatitis, Allergic Contact, Female, Humans, Lichens, Male, Middle Aged, Patch Tests, Plant Extracts, Resins, Plant, Retrospective Studies.
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Is contact sensitization to tree moss ( Evernia furfuracea extract , INCI ) heterogeneous? Context: Evernia prunastri (oak moss) and Evernia furfuracea (tree moss) are lichens from which natural extracts are obtained. To identify possible subgroups of E. furfuracea-sensitized patients according to whether these are allergic to lichen components or to contaminants. A retrospective analysis was performed of surveillance data collected by the Information Network of Departments of Dermatology (www.ivkd.org) in 2003-2010 with oak moss absolute (1% pet.), tree moss absolute (1% pet.), and colophonium (colophony, 20% pet.). In total, 3030 patients had been tested with all three allergens. Positive reactions to E. furfuracea were observed in 6.37%, to E. prunastri in 5.71%, and to colophonium in 4.82%. Concordance between positive reactions to E. prunastri and E. furfuracea was good only in patients not co-sensitized to colophonium (Cohen's κ = 0.681, 95% confidence interval 0.615-0.746). Moreover, E. furfuracea-sensitized patients showed (strong or extreme) concomitant reactions to colophonium significantly more often if not co-sensitized to E. prunastri.
assistant
Two subgroups of E. furfuracea-sensitized patients are identifiable: (i) those with sensitization to (oxidized) resin acids, as indicated by positive patch test reactions also to colophonium, and (ii) those non-sensitized to resin acids, but sensitized to common constituents of E. prunastri and E. furfuracea. Final Decision: yes