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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Ist urge of micturition comes at
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The correct answer is  When 100-150 millilitres (3.5-5 ounces) of urine accumulate, the first sensations of a need to void are felt. The feeling increases in intensity as more urine accumulates, and it becomes uncomfoable at a bladder volume of 350-400 millilitres. Impulses from the pelvic nerves mediate the sensations of bladder filling, painful distension, and the conscious need to urinate. Ref: guyton and hall textbook of medical physiology 12 edition page number:519,520,521