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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Aged, Cohort Studies, Comorbidity, Coronary Angiography, Coronary Artery Bypass, Coronary Artery Disease, Coronary Restenosis, Diabetes Complications, Elective Surgical Procedures, Female, Follow-Up Studies, Graft Occlusion, Vascular, Humans, Internal Mammary-Coronary Artery Anastomosis, Male, Middle Aged, Organ Specificity, Prospective Studies, Risk, Saphenous Vein, Stents.
user
Do patients with in-stent restenosis have an increased risk of mid-term venous graft failure? Context: This study was designed to evaluate if patients in whom in-stent restenosis developed had an higher risk of early venous graft failure compared with normal patients. The study cohort comprised 120 patients (60 with previous in-stent restenosis and 60 controls) who received a total of 165 complementary venous grafts on the circumflex or right coronary artery system (84 in the restenosis group and 81 in the control group). All patients were prospectively followed-up and underwent reangiography at 5-years follow-up. In the restenosis group, 28 venous grafts (33.%) were perfectly patent, 10 showed major irregularities, and 46 were occluded. In the control patients, 50 grafts (61.7%) were perfectly patent (p < 0.001 compared with the restenosis series), 12 showed major irregularities (p = .74), and 19 were occluded (p < 0.0001). In contrast, the 5-year outcome of internal thoracic artery grafts was not affected by history of in-stent restenosis.
assistant
Patients who developed in-stent restenosis have an higher risk of early venous graft failure compared with the control patients. Arterial grafts should probably be preferred in these patients. Final Decision: yes