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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Arthritis, Rheumatoid, C-Reactive Protein, Collagen, Disease Progression, Female, Humans, Male, Middle Aged, Peptides, Radioimmunoassay, Statistics, Nonparametric, Time Factors.
user
Does type I collagen degradation diminish with RA disease duration? Context: To assess the relation between type I collagen degradation and the duration of rheumatoid arthritis (RA). The serum concentrations of cross linked carboxyterminal telopeptide of type I collagen (ICTP) measured earlier in a community based series (90 patients) and a hospital based series (59 patients) were re-evaluated with reference to the duration of RA. The serum ICTP showed a positive correlation with the duration of the disease in the hospital based series (r(s)=0.40, p<0.01) but not in the community based one (r(s)=0.18, p=0.10).
assistant
Type I collagen degradation predominantly reflecting pathological bone destruction does not seem to diminish in longlasting RA. Final Decision: no