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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Prophylactic antibiotics are most effective during
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The correct answer is  In the first 4 hours, after a breach in an epithelial surface and underlying connective tissues, there is delay in the mobilisation of host defences. This period is called 'decisive period' and during this period, bacterial colonisation and established infection can begin. It is logical that prophylactic antibiotics will be most effective during this time.