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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Aged, Aged, 80 and over, Drug Therapy, Combination, Female, Fibrinolytic Agents, Humans, Male, Middle Aged, Mohs Surgery, Postoperative Hemorrhage, Retrospective Studies, Risk Factors, Skin Neoplasms.
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Do multiple antithrombotic agents increase the risk of postoperative hemorrhage in dermatologic surgery? Context: Studies show that holding single antithrombotic agents perioperatively increases the risk of acute thrombotic events and does not significantly decrease the risk of bleeding complications in dermatological surgery. Recent data suggest that selected patients may benefit from combination therapy in preventing acute thrombotic events. We sought to evaluate postoperative bleeding complications in patients who underwent Mohs micrographic surgery while using multiple agents perioperatively compared with patients using a single agent or none at all. We conducted a retrospective chart review of patients treated in one academic Mohs micrographic surgery department during 1 year. Patients taking two or more agents at the time of surgery were more likely to bleed than those taking one agent or none at all (P = .0016, Fisher's exact).
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Small sample size and retrospective nature were limitations. Final Decision: yes