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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Which of the following prokinetic drugs produces extrapyramidal side effects?
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The correct answer is  (Ref: KDT 6/e p643, 644) Metoclopramide and domperidone act by blocking D2 receptors. Metoclopramide can cross BBB whereas domperidone cannot. Therefore, metoclopramide can produce extra-pyramidal adverse effects while domperidone is devoid of it. Cisapride acts as 5HT4 agonist. It can cause torsades de pointes.