system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
True statement regarding development of drug resistance in MRSA is:
assistant
The correct answer is  Ans. (B) Occurs due to change in penicillin-binding proteins(Ref: Katzung's 11/e p776, KDT 8/e p743)Methicillin resistance occurs due to altered PBPs, thus no penicillin, (infact no beta-lactam antibiotic) is useful against methicillin-resistant Staphylococcus aureus (MRSA) infections.