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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which drugs action needs insulin presence to produce its therapeutic action?
assistant
The correct answer is  Metformin and glitazones require insulin for their action as they are just insulin sensitizers not releasers. They sensitize the tissue to insulin hence require insulin for their action. Ref: KD Tripathi 8th ed.