system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Aggression, Analysis of Variance, Competitive Behavior, Confidence Intervals, Female, Humans, Luteal Phase, Middle Aged, Premenstrual Syndrome, Serotonin, Tryptophan.
user
Does tryptophan depletion increase aggression in women during the premenstrual phase? Context: Reducing serotonin by the method of tryptophan depletion (TD) has led to increased aggression but experimental studies have not used female subjects. To evaluate the effects of TD on aggression in women in the late luteal phase of their menstrual cycle. Healthy women were recruited and randomly assigned to an amino acid drink either depleted or with a balanced amount of tryptophan. At 4.5 h later, they competed on the competitive reaction time task. Women who had received the TD drink showed more behavioural aggression in response to provocation.
assistant
Decreased serotonergic neurotransmission increases aggression in women as well as men. Final Decision: yes