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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Atracurium is metabolized by -
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The correct answer is  Ans. B. Hoffman degradationThe unique feature of atracurium is inactivation in plasma by spontaneous non enzymatic degradation (Hofmann elimination).Consequently its duration of action is not altered in patients with hepatic/renal insufficiency or hyperdynamic circulation ---> Hence, preferred muscle relaxant for such patients as well as for neonates and the elderly.Atracuum is metabolised to laudanosine that is responsible for seizures.Cause histamine release > Hypotension, bronchoconstriction & flushing.