system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Biomarkers, Chorionic Gonadotropin, beta Subunit, Human, Female, Fetal Growth Retardation, Humans, Pre-Eclampsia, Predictive Value of Tests, Pregnancy, Pregnancy Trimester, First, Pregnancy-Associated Plasma Protein-A, Young Adult.
user
βhCG and PAPP-A in first trimester: predictive factors for preeclampsia? Context: The aim of our study was to investigate a possible correlation between the expression of the placenta-secreted hormones, β-subunit of human chorionic gonadotrophin (βhCG) and pregnancy-associated plasma protein A (PAPP-A), during the first trimester screening and the development of preeclampsia. A total of 155 patients between 11 + 0 and 13 + 6 weeks of gestation were enrolled in this study. PAPP-A and βhCG levels were measured using the KRYPTOR® system. The serum levels of βhCG were significantly higher in pregnancies which subsequently developed preeclampsia. The PAPP-A concentration did not differ significantly in pregnancies complicated by preeclampsia than in uncomplicated pregnancies.
assistant
These results might contribute to developing new tests in the prediction of preeclampsia.