system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Peau d' orange is due to -
assistant
The correct answer is  Peaud's orange is produced due to obstruction of superficial lymph vessels by cancer cells. This causes edema of the skin giving rise to an appearance like that of the skin of an orange (Peau'd orange appearance) Ref - Srb's manual of surgery 5e p534