system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE. Meshes: Age Factors, Alanine, Amino Acids, Arginine, Chorionic Gonadotropin, Chromatography, High Pressure Liquid, Female, Follicle Stimulating Hormone, Glutamic Acid, Glutamine, Gonadotropins, Humans, Infertility, Female, Isoleucine, Kinetics, Lysine, Metaphase, Oocytes, Ovulation Induction, Polycystic Ovary Syndrome, Serine, Valine.
user
Is amino acid turnover by human oocytes influenced by gamete developmental competence , patient characteristics and gonadotrophin treatment? Context: Can amino acid profiling differentiate between human oocytes with differing competence to mature to metaphase II (MII) in vitro?
assistant
Oocytes which remained arrested at the germinal vesicle (GV) stage after 24 h of in vitro maturation (IVM) displayed differences in the depletion/appearance of amino acids compared with oocytes which progressed to MII and patient age, infertile diagnosis and ovarian stimulation regime significantly affected oocyte amino acid turnover during IVM. Final Decision: yes