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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
In pemphigus circulating antibodies attack:
assistant
The correct answer is  Pemphigus

Is a skin and mucous membrane disease with autoimmune etiology.
Characterized histologically by intradermal blisters circulating IgG (IgG1 and IgG4) antibody against keratinocyte cell surface (attack Desmoglein 1 and 3).