system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 25-year-old woman is admitted to the intensive care unit (ICU) with hematemesis and shock. Five days ago she had a severe fever 40.0℃ (104.0℉), retro-orbital pain, nausea, and myalgias. The high temperatures decreased over a few days, but she developed severe abdominal pain and bleeding gums. A single episode of hematemesis occurred prior to ICU admission. She travels to Latin America every winter. Two weeks ago, she traveled to Brazil and spent most of her time outdoors. She is restless. The temperature is 38.0℃ (100.4℉), the pulse is 110/min, the respiration rate is 33/min, and the blood pressure is 90/70 mm Hg. Conjunctival suffusion is seen. The extremities are cold. A maculopapular rash covers the trunk and extremities. Ecchymoses are observed on the lower extremities. The lung bases reveal absent sounds with dullness to percussion. The abdomen is distended. The liver edge is palpable and liver span is 15 cm. Shifting dullness is present. The laboratory studies show the following:
Laboratory test
Hemoglobin 16.5 g/dL
Leukocyte count 3500/mm3
Segmented neutrophils 55%
Lymphocytes 30%
Platelet count 90,000/mm3
Serum
Alanine aminotransferase (ALT) 75 U/L
Aspartate aminotransferase (AST) 70 U/L
Total bilirubin 0.8 mg/dL
Direct bilirubin 0.2 mg/dL
Which of the following is the most likely diagnosis?
assistant
Dengue fever