system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
All of the following effects are produced by inhibitors of prostaglandin synthesis EXCEPT:
assistant
The correct answer is  Prothrombin time is increased by the drugs interfering with the coagulation pathway (e.g. warfarin). As COX has no role in coagulation, inhibitors of PG synthesis do not prolong PT. However, bleeding time (BT) is prolonged by the drugs interfering with platelet function. Aspirin increases BT by acting as an antiplatelet agent.