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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, RESULTS. Meshes: Administration, Topical, Analysis of Variance, Animals, Anti-Infective Agents, Local, Antifungal Agents, Baths, Chlorhexidine, Ctenocephalides, Dog Diseases, Dogs, Female, Flea Infestations, Insecticides, Ketoconazole, Male, Oxazines.
user
Do flea ( Ctenocephalides felis ) control efficacy of topical indoxacarb on dogs subsequently bathed with a chlorhexidine-ketoconazole shampoo? Context: An evaluation of the effect of chlorhexidine/ketoconazole shampoo baths on the flea control efficacy of indoxacarb applied topically to dogs. We randomly allocated 18 healthy mixed-breed dogs to 3 groups: shampoo only; indoxacarb treated and medicated shampoo; and indoxacarb treated but not shampooed. Indoxacarb was administered on day 0 and dogs were shampooed on days 9 and 23. Dogs were infested with 100 adult Ctenocephalides felis initially 2 days before treatment and then weekly from days 7 to 28. Fleas were removed and counted 48 h post-infestation.
assistant
Medicated shampoo use did not significantly reduce indoxacarb efficacy against C. felis. Final Decision: yes