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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Case-Control Studies, Cholecystitis, Chronic Disease, Gallbladder, Helicobacter Infections, Helicobacter pylori, Humans, Interleukin-1, Interleukin-6, Interleukin-8, Metaplasia, Mucous Membrane.
user
Are h pylori associated with chronic cholecystitis? Context: To study whether H pylori are associated with chronic cholecystitis. The subjects were divided into three groups: H pylori-infected cholecystitis group, H pylori-negative cholecystitis group and control group. Pathologic changes of the gallbladder were observed by optic and electronic microscopes and the levels of interleukin-1, 6 and 8 (IL-1, 6 and 8) were detected by radioimmunoassay. Histological evidence of chronic cholecystitis including degeneration, necrosis, inflammatory cell infiltration, were found in the region where H pylori colonized. Levels of IL-1, 6 and 8 in gallbladder mucosa homogenates were significantly higher in H pylori-infected cholecystitis group than those in H pylori-negative cholecystitis group and control group.
assistant
H pylori infection may be related to cholecystitis. Final Decision: yes