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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following medications is contraindicated in patients with allergy to sulphonamides?
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The correct answer is  Acetazolamide, Dorzolamide and Brinzolamide are sulfonamide derivatives which act by inhibiting carbonic anhydrase (carbonic anhydrase inhibitor). Being sulphonamide derivatives they are contraindicated in patients with allergy to sulphonamides. Ref: Essentials of Pharmacology By K D Tripathi, 5th Edition, Pages 188, 553; Medicinal Chemistry By Sriram, Page 227.