system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Pre conceptional intake of which of the following will decrease the incidence of neural tube defects?
assistant
The correct answer is  Prophylactic folic acid supplementation in  2nd and 3rd  trimester along with Vit. K in the last month of pregnancy is recommended, particularly in women receiving antiepileptic drugs to minimise neural tube defects and bleeding disorder respectively in the neonate.
Reference: Essentials of Medical Pharmacology Eighth Edition KD  TRIPATHI  page no 449