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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Co-infection is essential for disease presentation is
assistant
The correct answer is  majority of patients with HDV superinfection evolve to chronic HDV infection and hepatitis. Two major patterns of infection have been described: coinfection with HBV and HDV, or superinfection with HDV of a person chronically infected with HBV Ref Harrison20th edition pg 980