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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Allergic reactions occur with amino ester local anesthetics due to its metabolite:
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The correct answer is  p-Aminobenzoic acid is one of the metabolites of ester-type compounds that can induce allergic-type reactions in a small percentage of patients. The aminoamides are not metabolized to p-aminobenzoic acid, and repos of allergic reactions to these agents are extremely rare. Ref: Miller's anesthesia-7th ed , Chapter 30.