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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Best test to detect iron deficiency anemia in a community with low prevalence of iron deficiency is: March 2013
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The correct answer is  Ans. D i.e. Serum ferritin In the appropriate clinical setting, a smear showing hypochromia and microcytosis is adequate for the diagnosis. When more specific tests are needed, a positive diagnosis can be made from low levels of ferritin, and a low serum iron level in association with an elevated total iron binding capacity. Iron deficiency anemia (IDA): Commonest cause of anemia in India Increased iron absorption is seen in: Iron deficiency anemia, pregnancy, hypoxia, acidic pH of stomach, ferrous iron salts Causes of IDA: Hookworms, celiac sprue, carcinoma colon Features diagnostic of IDA: Decreased serum ferritin, increased TIBC Earliest sign of IDA: Decrease in serum ferritin Most sensitive and specific test for diagnosing IDA: Serum ferritin levels Hypochromia may be preceded by microcytosis