system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Hepatitis B remains in latent period for a long time but still there is increased risk of HCC, what is the cause of this transformation?
assistant
The correct answer is  ANS. DLet us analyze this question by looking at each option.Option A is a correct statement, but inability to induce inflammation is not the cause for transformation into hepatocellular carcinoma.Option B is not definitely the cause for HCC as elevated transaminases does not have anything to do with HCC.Option C is not correct as in latent period, there is no proliferation of hepatocytes.Option D is the answer and integration of viral DNA with host DNA causes transformation into HCC.