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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Impaired function of Aquaporin results in
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The correct answer is  ADH acts V2 receptors on DCT casuing facultative reabsorption of water by inseing Aquaporin -2 channels into apical (luminal side ). Nephrogenic DI-defect in aquaporins BATER SYNDROME - Autosomal recessive Defect in"Na-K-2Cl cotranspoer, Cl channel & ROMK"in loop of Henle LIDDLE SYNDROME - Gain of function of epithelial Na channel (ENaC) Cystic fibrosis - CH-7 defect in CFTR gene - causing defect in transmembrane chloride ion regulation.