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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Adolescent, African Continental Ancestry Group, Blood Pressure, Female, Humans, Hypertension, Male, Natriuresis, Sodium, Stress, Physiological, Vascular Resistance.
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Does impaired stress-induced pressure natriuresis increase cardiovascularload in African American youths? Context: We hypothesized that impaired stress-induced pressure natriuresis increases blood pressure (BP) load. The 118 African American youths were brought into similar levels of sodium balance. The protocol consisted of a 2-h baseline period, a 1-h stress period (competitive video games), and a 2-h recovery period. Normal pressure natriuresis (n = 80) resulted from a resistance-mediated (r = 0.23; P <.03) increase in BP (P <.001). In contrast, impaired pressure natriuresis (n = 38), leading to an extended period of elevated BP (P <.05), resulted from a volume-mediated (r = 0.55; P <.002) increase in BP (P <.001).
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Impaired stress-induced pressure natriuresis may contribute to the development of essential hypertension, particularly in African Americans. Final Decision: yes