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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Animals, Antineoplastic Agents, Aquaporin 4, Body Weight, Feces, Female, Fluorouracil, Inflammation, Intestinal Mucosa, Mucositis, Oocytes, Peroxidase, Plant Extracts, Rats, Rheum, Xenopus.
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Does rhubarb extract partially improve mucosal integrity in chemotherapy-induced intestinal mucositis? Context: To investigate the effects of orally gavaged aqueous rhubarb extract (RE) on 5-fluorouracil (5-FU)-induced intestinal mucositis in rats. Female Dark Agouti rats ( Bodyweight was significantly reduced in rats administered 5-FU compared to healthy controls (
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In summary, low dose RE improves selected parameters of mucosal integrity and reduces ileal inflammation, manifesting from 5-FU-induced intestinal mucositis. Final Decision: yes