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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, METHODS, METHODS, METHODS, METHODS, RESULTS. Meshes: Adenocarcinoma, Aged, Barrett Esophagus, Esophageal Neoplasms, Esophagoscopy, Female, Humans, Male, Middle Aged, Mucous Membrane, Population Surveillance, Precancerous Conditions, Statistics, Nonparametric, Time Factors.
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Is longer inspection time associated with increased detection of high-grade dysplasia and esophageal adenocarcinoma in Barrett 's esophagus? Context: Current guidelines recommend that endoscopic surveillance of Barrett's esophagus (BE) be performed by using a strict biopsy protocol. However, novel methods to improve BE surveillance are still needed. To evaluate the impact of Barrett's inspection time (BIT) on yield of surveillance. Post hoc analysis of data obtained from a clinical trial. Five tertiary referral centers. Patients undergoing BE surveillance. Coordinators prospectively recorded the time spent inspecting the BE mucosa with a stopwatch. Endoscopically suspicious lesions, high-grade dysplasia (HGD)/esophageal adenocarcinoma (EAC). A total of 112 patients underwent endoscopic surveillance by 11 individual endoscopists. Patients with longer BITs were more likely to have an endoscopically suspicious lesion (P < .001) and more endoscopically suspicious lesions (P = .0001) and receive a diagnosis of HGD/EAC (P = .001). There was a direct correlation between the endoscopist's mean BIT per centimeter of BE and the detection of patients with HGD/EAC (ρ = .63, P = .03). Endoscopists who had an average BIT longer than 1 minute per centimeter of BE detected more patients with endoscopically suspicious lesions (54.2% vs 13.3%, P = .04), and there was a trend toward a higher detection rate of HGD/EAC (40.2% vs 6.7%, P = .06).
assistant
Post hoc analysis of an enriched study population and experienced endoscopists at tertiary referral centers. Final Decision: yes