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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, METHODS, METHODS, RESULTS. Meshes: Adult, Alkalies, Anesthesia, Caudal, Bicarbonates, Humans, Hydrogen-Ion Concentration, Mepivacaine, Nerve Block, Sacrum, Time Factors.
user
Does alkalinization of mepivacaine alter onset of caudal anesthesia? Context: To determine the effect of alkalinization of mepivacaine on onset of caudal anesthesia. Randomized, blind study. Colon-Rectal Surgery Service of the Tertiary Center at Cleveland Clinic Foundation. Young, healthy adults undergoing anal surgery. Addition of bicarbonate (study group) or saline (control group) to mepivacaine. At the onset of sacral anesthesia, demographics were measured. A slightly faster onset was found in the study group (4.28 vs. 6.08 minutes), but this was not statistically significant.
assistant
Alkalinization of mepivacaine does not significantly accelerate the onset of caudal anesthesia. Final Decision: no