system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 69-year-old woman comes to the physician because of a 3-week history of headache and worsening vision. Ophthalmologic examination shows a visual acuity of 20/120 in the right eye and 20/80 in the left eye. Physical examination shows no other abnormalities. Laboratory studies show a hemoglobin of 14.2 g/dL and total serum calcium of 9.9 mg/dL. A photomicrograph of a peripheral blood smear is shown. Serum electrophoresis shows increased concentration of a pentameric immunoglobulin. Which of the following is the most likely diagnosis?
assistant
Waldenstrom macroglobulinemia