system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, RESULTS. Meshes: Amino Acids, Ammonia, Animal Feed, Animals, Anti-Bacterial Agents, Bacteria, Cattle, Humulus, Plant Extracts, Rumen.
user
Does the antimicrobial effects of hop ( Humulus lupulus L. ) on ruminal hyper ammonia-producing bacteria? Context: To assess the antimicrobial effects of hops (Humulus lupulus L.) on hyper ammonia producing-bacteria (HAB), which catabolize amino acids and peptides in the bovine rumen. When media were amended with dried hops or hops extract (30.7% lupulone), ammonia production by mixed rumen bacteria was inhibited. The growth and ammonia production of pure cultures (Peptostreptococcus anaerobius, Clostridium aminophilum, or Clostridium sticklandii) was inhibited by 30 ppm lupulone at pH 6.7, and bactericidal activity was observed at pH 5.6. When hops extract was added to energized cell suspensions, the intracellular pH rapidly decreased and intracellular potassium was lost.
assistant
The three HAB species were sensitive to the antimicrobial components in hops, and the inhibition of ammonia production by mixed rumen bacteria indicates that similar effects could be expected in the rumen. Final Decision: yes