system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Long-term use of which diuretic agent can result in gynaecomastia?
assistant
The correct answer is  Side effects of spironolactone: - Drowsiness, Ataxia, Mental confusion, Epigastric distress It may enhance testosterone clearance or its peripheral conversion to estradiol- gynecomastia, erectile dysfunction or loss of libido in men, and breast tenderness or menstrual irregularities in women. Most serious is hyperkalemia that may occur, especially if renal function is inadequate.