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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Attention, Autistic Disorder, Data Interpretation, Statistical, Electroencephalography, Electrophysiology, Evoked Potentials, Female, Humans, Intellectual Disability, Male, Photic Stimulation, Saccades, Space Perception, Visual Fields, Visual Perception.
user
Do electrophysiological abnormalities of spatial attention in adults with autism during the gap overlap task? Context: We evaluated event-related potentials (ERPs) elicited by attentional disengagement in individuals with autism. Sixteen adults with autism, 17 adults with mental retardation and 14 healthy adults participated in this study. We recorded the pre-saccade positive ERPs during the gap overlap task under which a peripheral stimulus was presented subsequent to a stimulus in the central visual field. Under the overlap condition, the central stimulus remained during the presentation of the peripheral stimulus and therefore participants need to disengage their attention intentionally in order to execute the saccade to the peripheral stimulus due to the preservation of the central stimulus. The autism group elicited significantly higher pre-saccadic positivity during a period of 100-70 ms prior to the saccade onset than the other groups only under the overlap condition. The higher amplitude of pre-saccadic positivity in the overlap condition was significantly correlated with more severe clinical symptoms within the autism group.
assistant
These results demonstrate electrophysiological abnormalities of disengagement during visuospatial attention in adults with autism which cannot be attributed to their IQs. Final Decision: yes