system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 6-month-old girl presents with recurring skin infections. Past medical history is significant for 3 episodes of acute otitis media since birth. The patient was born at 39 weeks via an uncomplicated, spontaneous transvaginal delivery, but there was delayed umbilical cord separation. She has met all developmental milestones. On physical examination, the skin around her mouth is inflamed and red. Which of the following is most likely responsible for this child’s clinical presentation?
assistant
Absence of CD18 molecule on the surface of leukocytes