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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, RESULTS. Meshes: Adolescent, Adult, Aged, Catheterization, Female, Follow-Up Studies, Glucocorticoids, Granulomatosis with Polyangiitis, Humans, Injections, Intralesional, Laryngoscopy, Laryngostenosis, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Young Adult.
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Does intralesional corticosteroid injection and dilatation provide effective management of subglottic stenosis in Wegener 's granulomatosis? Context: To describe our experience with the use of intralesional corticosteroid injection and dilatation (ILCD) in the management of subglottic stenosis (SGS). Retrospective chart review. A retrospective chart review was performed of all patients with SGS requiring ILCD, from 2003 to 2008, at the Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Hospital, Toronto, Canada. Twelve patients with SGS underwent 36 ILCD operations with a mean of three procedures per patient. We identified eight patients with Wegener's granulomatosis (WG) and four patients without WG. The eight WG patients received an average of 3.37 procedures, whereas non-WG patients required an average of 2.25 procedures. This maintained airway patency and symptom control for an average of 11.9 and 8.1 months, respectively. Only one complication was identified, and no long-term sequelae were found. No patients required new tracheotomies and one patient with a previous tracheotomy was successfully decannulated.
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Our data supports the use of ILCD as a safe and effective treatment of SGS in both WG and non-WG patients. Final Decision: yes