system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: 3-Hydroxybutyric Acid, Acetoacetates, Adult, Aged, Female, Hepatectomy, Humans, Hydroxybutyrates, Ischemia, Ketone Bodies, Liver, Liver Function Tests, Male, Middle Aged, Mitochondria, Liver, Oxidation-Reduction.
user
Does arterial ketone body ratio correlate with ischemic changes during major hepatectomy? Context: The arterial ketone body ratio (AKBR) has been proposed as an accurate indicator of hepatic mitochondrial redox potential. However, recent studies of the utility of the AKBR as a biochemical marker have been called into question. It is not clear whether the AKBR is closely related to ischemic changes during major hepatectomy. Arterial acetoacetate and beta-hydroxybutyrate concentrations were measured in eleven patients who underwent major hepatectomy. The ratio between them (AKBR) was calculated before and after vascular occlusion during the hepatectomy procedure. The AKBR increased following normothermic arterial or portal venous ischemia as compared to the levels prior to vascular occlusion in 36.4% of the patients who underwent major hepatectomy. An AKBR of less than 0.5 prior to vascular occlusion did not correlate with preoperative hepatocellular function. An AKBR of less than 0.7 throughout surgery was not a consistent risk factor for postoperative complications or liver dysfunction.
assistant
The AKBR does not correlate with ischemic changes or postoperative complications after major hepatectomy. Final Decision: no