system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE. Meshes: Adolescent, Adult, Antigens, CD, Antigens, Differentiation, Myelomonocytic, B7-2 Antigen, Cell Differentiation, Cell Movement, Cell Proliferation, Cell Survival, Cytokines, Decidua, Escherichia coli, Female, Granulocyte-Macrophage Colony-Stimulating Factor, HLA-G Antigens, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Macrophages, Middle Aged, Monocytes, Phagocytosis, Phenotype, Pre-Eclampsia, Pregnancy, Receptors, Cell Surface, Recombinant Proteins, T-Lymphocytes, Trophoblasts, Young Adult.
user
Does soluble human leukocyte antigen G5 polarize differentiation of macrophages toward a decidual macrophage-like phenotype? Context: What are the actions of soluble human leukocyte antigen G5 (sHLAG5) on macrophage differentiation?
assistant
sHLAG5 polarizes the differentiation of macrophages toward a decidual macrophage-like phenotype, which could regulate fetomaternal tolerance and placental development. Final Decision: yes