system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
All of the following acute myeloid leukemia are diagnosed regardless of blast count except
assistant
The correct answer is  WHO classification mandates diagnosis of AML only when >20% blasts are present in the marrow. However, in the following three scenarios, this is overruled and AML may be diagnosed even if blast count is <20%.

AML with t(8;21)
AML with t(15;17)
AML with inv (16) or t(16;16)