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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Holt Aram syndrome is caused by mutation of:
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The correct answer is  Mutations in the TBX5 gene result in Holt-Oram syndrome, characterized by preaxial (radial) limb abnormalities and atrial septal defects.Ref: LANGMAN'S EMBRYOLOGY 11TH ED Chapter 12.