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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, METHODS, METHODS, RESULTS. Meshes: Adolescent, Adult, Analysis of Variance, Anti-Infective Agents, Bone Marrow Transplantation, Ciprofloxacin, Female, Hodgkin Disease, Humans, Lymphoma, Non-Hodgkin, Male, Middle Aged, Neutropenia, Neutrophils, Retrospective Studies, Transplantation, Autologous.
user
Does prolonged ciprofloxacin administration accelerate neutrophil recovery after autologous bone marrow transplantation? Context: To determine whether prolonged ciprofloxacin administration following autologous bone marrow transplantation (ABMT) accelerates neutrophil recovery. Retrospective analysis of 40 consecutive patients undergoing ABMT. Tertiary care bone marrow transplant program. Two sequential arms of 20 consecutive patients with Hodgkin's disease or non-Hodgkin's lymphoma undergoing ABMT. The first arm received ciprofloxacin from the day of transplantation until initiation of broad-spectrum antibiotic therapy (median 5 days) while the second arm continued ciprofloxacin until recovery of the neutrophil count (median 15 days). Neutrophil recovery was similar in the two groups (16 vs 14 days; p = 0.41). There were no differences in platelet recovery, bacteremia, or treatment-related mortality.
assistant
Prolonged ciprofloxacin administration does not significantly accelerate neutrophil recovery following ABMT. Final Decision: no