system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 61-year-old man comes to the physician because of a 2-month history of severe chest discomfort. The chest discomfort usually occurs after heavy meals or eating in the late evening and lasts several hours. He has nausea sometimes but no vomiting. He has also had an occasional nighttime cough during this period. He has hypertension and type 2 diabetes mellitus. He has smoked one pack of cigarettes daily for the past 41 years and drinks one beer daily. Current medications include metformin, naproxen, enalapril,and sitagliptin. He is 177 cm (5 ft 10 in) tall and weighs 135 kg (297 lb); BMI is 43 kg/m2. Vital signs are within normal limits. Cardiopulmonary examination shows no abnormalities. The abdomen is soft and nontender. Laboratory studies are within the reference ranges. An ECG shows no abnormalities. An upper endoscopy shows that the Z-line is located 4 cm above the diaphragmatic hiatus and reveals the presence of a 1.5-cm esophageal ulcer with an erythematous base and without bleeding. The physician recommends weight loss as well as smoking and alcohol cessation. Treatment with omeprazole is begun. One month later, his symptoms are unchanged. Which of the following is the most appropriate next step in management?
assistant
Laparoscopic Nissen fundoplication with hiatoplasty