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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, METHODS, RESULTS. Meshes: Adult, Biliopancreatic Diversion, Blood Glucose, Body Mass Index, Case-Control Studies, Diabetes Mellitus, Type 2, Fasting, Female, Glucose, Glucose Tolerance Test, Humans, Infusions, Intravenous, Insulin, Insulin Resistance, Insulin-Secreting Cells, Male, Obesity, Morbid, Postoperative Care, Prospective Studies, Sweetening Agents, Weight Loss.
user
Do restoration of high-frequency glucose-entrained insulin oscillations in obese subjects with type 2 diabetes after biliopancreatic diversion? Context: Minimal glucose infusions are known to entrain insulin oscillations in patients with normal glucose tolerance (NGT) but not in patients with type 2 diabetes (T2D). To investigate whether weight loss after a version of biliopancreatic diversion (BPD) can restore the glucose entrainment of high-frequency insulin oscillations in morbidly obese NGT or T2D patients. University Hospital, Greece. We prospectively studied 9 NGT controls (body mass index [BMI] 23.3±1.6 kg/m Postoperatively, glucose and insulin concentrations of NGT and T2D patients decreased to control levels and BMI to 31.3±6.3 for NGT patients and 34.9±9.9 kg/m
assistant
BPD restores the glucose entrainment of high-frequency insulin oscillations in obese NGT and T2D patients after marked weight loss and normalizes glucose levels and insulin sensitivity, thus demonstrating recovery of β-cell glucose sensing. Final Decision: yes