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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Adult, Aged, Aged, 80 and over, Area Under Curve, Baltimore, Biomarkers, Delayed Graft Function, Enzyme-Linked Immunosorbent Assay, Female, Humans, Immunosuppressive Agents, Interleukin-16, Interleukin-2 Receptor alpha Subunit, Kidney Diseases, Kidney Failure, Chronic, Kidney Transplantation, Logistic Models, Male, Middle Aged, Predictive Value of Tests, Prospective Studies, Reperfusion Injury, Stem Cell Factor, Time Factors, Treatment Outcome.
user
Are stem cell factor , interleukin-16 , and interleukin-2 receptor alpha predictive biomarkers for delayed and slow graft function? Context: Delayed graft function (DGF) and slow graft function (SGF) due to ischemic and reperfusion injury (IRI) are common complications of deceased donor kidney transplantation. We tested whether a panel of serum and urine cytokines represent early biomarkers for DGF and SGF. We collected serum and urine samples from 61 patients 48 hours posttransplantation and used a multiplex enzyme-linked immunosorbent assay (ELISA) technique to measure levels of 23 cytokines. Fourteen patients developed poor graft function (PGF), with 6 having DGF and 8 with SGF. Area under receiver operation characteristics curve (AUC) demonstrated the following: serum levels of SCF (0.88) and interleukin (IL) 16 (0.74).
assistant
This study showed that a select panel of cytokines measured early post kidney transplantation may predict poor graft function. Final Decision: yes