system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, RESULTS. Meshes: Animals, Cell Differentiation, Cell Line, Down-Regulation, Dual Specificity Phosphatase 1, MEF2 Transcription Factors, Mice, MicroRNAs, MyoD Protein, Myoblasts, Myogenic Regulatory Factors, Receptor, Notch3, Receptors, Notch, Signal Transduction.
user
Are notch3 and Mef2c proteins mutually antagonistic via Mkp1 protein and miR-1/206 microRNAs in differentiating myoblasts? Context: Notch3 is expressed in myogenic precursors, but its function is not well known. Notch3 represses the activity of Mef2c and is in turn inhibited by the microRNAs-1 and -206.
assistant
Notch3 serves as a regulator for preventing premature myogenic differentiation. Final Decision: yes