system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Early epiphyseal closure is seen with _________
assistant
The correct answer is  The growth velocity decreases and may even be zero after epiphyseal fusion, that is, after growth plate closure in late pubey. Precocious pubey (PP) is a known cause of sho stature after earlier pubey due to premature closure of growth plates in long bones Precocious pubey may be due to increased estrogen . Ref : Nelson paediatrics Chapter : Growth and deve