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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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The rate-limiting step in glycolysis is catalyzed by
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The correct answer is  Step 3 of Glycolysis Fructose-6-phosphate is fuher phosphorylated to fructose1,6-bisphosphate. The enzyme is phosphofructokinase. ii.PFK is an allosteric, inducible, regulatory enzyme. It is an impoant key enzyme of this pathway. This is again an activation process, the energy being derived by hydrolysis of yet another molecule of ATP. ). This irreversible step is the rate-limiting reaction in glycolysis. However, during gluconeogenesis, this step is circumvented by fructose-1,6-bisphosphatase.Ref: DM Vasudevan, 7th edition, page no: 109