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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, METHODS, RESULTS, RESULTS. Meshes: Adolescent, Adult, Aged, Aged, 80 and over, Biomarkers, Cardiovascular Diseases, Child, Cohort Studies, Diagnostic Tests, Routine, Female, Follow-Up Studies, Humans, Male, Middle Aged, Peritoneal Dialysis, Peritoneum, Peritonitis, Predictive Value of Tests, Protein Transport, Treatment Outcome, Young Adult.
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Is peritoneal protein transport during the baseline peritoneal equilibration test an accurate predictor of the outcome of peritoneal dialysis patients? Context: Peritoneal protein excretion (PPE) is a potential marker of the outcome in peritoneal dialysis (PD) patients. Observational study of a cohort of 269 patients starting PD in a single unit. total PPE during a baseline peritoneal equilibration test (PET; PET-PPE) and 24-hour PPE. Control variables: essential baseline demographic, laboratory and adequacy markers. mortality, cardiovascular events and risk of peritonitis. We applied univariate and multivariate strategies of survival analysis. PET-PPE sustained a significant, yet limited correlation with 24-hour PPE (r = 0.46, p < 0.0005). At baseline, the main study variables showed an independent correlation with peritoneal transport characteristics (D/P(240') creatinine) and cardiovascular comorbidity. PET-PPE (p < 0.0005, model global χ(2) 59.4) was a more accurate predictor of overall mortality than 24-hour PPE (p = 0.04, χ(2) 50.5). Moreover, PPE during PET, but not 24-hour PPE, was an independent predictor of the risks of cardiovascular and infectious mortality, and of peritonitis.
assistant
Baseline PPE represents a strong independent marker of survival of PD patients. Estimation of PPE during PET is more accurate than 24-hour PPE for this purpose, sustains a definite independent association with cardiovascular and infectious mortality, and shows a significant correlation with the risk of peritonitis. Final Decision: yes