system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Pethidine should not be given with -
assistant
The correct answer is  Ans. is `d' i.e., MAO inhibitors o MAO inhibitors inhibit hydrolysis but not detmethylation --> more norpethidine is produced. Hydrolysis Mepridinic acid (major metabolic) Pethidine Dernekiation Norpethidine (minor metabolite) o MAO inhibitors selectively inhibit its hydrolysis without effecting demethylation -4 Accumulation of norpethidine --> Excitement.