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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
What is the best management option in a patient with COPD, with low SpO2 at rest?
assistant
The correct answer is  In COPD, non-uniform ventilation and ventilation-perfusion mismatching leads to localized vasoconstriction Supplemental oxygen abolishes this constriction, leading to improved ventilation/perfusion ratio. High flow oxygen is not tolerated as it leads to crusting, dryness and epistaxis. While continuous therapy is required for patients who show hypoxemia at rest, intermittent treatment during specific periods may be used for patients who demonstrate intermittent hypoxemia.