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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Eutectic mixture of local anaesthetic (EMLA) cream is
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The correct answer is  Eutectic mixture of local anaesthetic (EMLA)This is unique topical preparation which can anaesthetize the intact skinIt is a mixture of 2.5% lidocaine and 2.5 prilocaineIt acts slowly and the cream must head in contact with the skin for at least 1 hourEMLA is used: to make venepuncture painless especially for children, and for the procedure like skin grafting & circumcisionAs systemic absorption of prilocaine can cause methemoglobinemia, EMLA should not be used on the mucocutaneous membrane or in very small child.(Refer: Morgan and Mikhail's Clinical Anaesthesiology, 5th edition, pg no. 754, 856)