system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 70-year-old man comes to the physician because of a 2-month history of progressive shortness of breath and a dry cough. He has also noticed gradual development of facial discoloration. He has not had fevers. He has coronary artery disease, hypertension, and atrial fibrillation. He does not smoke or drink alcohol. He does not remember which medications he takes. His temperature is 37°C (98.6°F), pulse is 90/min, respirations are 18/min, and blood pressure is 150/85 mm Hg. Pulse oximetry on room air shows an oxygen saturation of 95%. Examination shows blue-gray discoloration of the face and both hands. Diffuse inspiratory crackles are heard. Laboratory studies show:
Prothrombin time 12 seconds (INR=1.0)
Serum
Na+ 142 mEq/L
Cl- 105 mEq/L
K+ 3.6 mEq/L
HCO3- 25 mg/dL
Urea Nitrogen 20
Creatinine 1.2 mg/dL
Alkaline phosphatase 70 U/L
Aspartate aminotransferase (AST, GOT) 120 U/L
Alanine aminotransferase (ALT, GPT) 110 U/L
An x-ray of the chest shows reticular opacities around the lung periphery and particularly around the lung bases. The most likely cause of this patient's findings is an adverse effect to which of the following medications?"
assistant
Amiodarone