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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
LE cell is seen in ?
assistant
The correct answer is  Ans. is 'a' i.e., Lupus erythematousus In SLE, antinuclear antibodies (AN Ps) can not penetrate intact cells. However, nuclei are exposed, ANA can bind to them. In tissues, nuclei of damaged cells react with ANAs, lose their chromatin pattern, and become homogeneous, to produce lupus - erythematous (LE) bodies or hemotoxylin bodies. When these LE bodies are engulfed by phagocytic cells (neutrophil or macrophage/monocyte), the phagocytic cells are called LE cells.