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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, METHODS, METHODS, METHODS, RESULTS. Meshes: Animals, Blood Gas Analysis, Disease Models, Animal, Extravascular Lung Water, Hemodynamics, Lung Compliance, Oleic Acid, Prone Position, Pulmonary Edema, Pulmonary Gas Exchange, Random Allocation, Respiratory Distress Syndrome, Adult, Respiratory Mechanics, Swine, Treatment Outcome.
user
Does abdomen release in prone position improve oxygenation in an experimental model of acute lung injury? Context: To analyze the effect of abdomen release in the prone position on oxygenation in an experimental model of acute lung injury. Experimental randomized controlled study. Experimental laboratory of a tertiary university hospital. Mixed-breed adolescent pigs weighing between 25-31 kg. Thirty minutes after pulmonary edema was produced with oleic acid, the animals were turned prone and randomized into two groups: group I or control (n = 9), lying directly on the operating table; and group II (n = 11) with abdomen release, with positioning rolls under the upper part of the chest wall and the pelvis to allow free movement of the abdomen. The gas exchange, respiratory mechanics, hemodynamics, intra-abdominal pressure (IAP) and the extravascular lung water (EVLW), determined by double indicator dilution method (DI), were recorded at baseline (time 0) and at 30, 60, 90, 120 and 150 min. The PaO2/FIO2 increased in both groups at 30 min after the pigs were placed in the prone position (time 60) and then decreased progressively until the end of the experimental period, with no statistical differences between the groups at any time (73.1 +/- 14.5 vs 79.5 +/- 14.9 at 150 min). Abdomen release was not associated with changes in the respiratory mechanics, EVLW or intra-abdominal pressure.
assistant
Abdomen release in prone position does not improve oxygenation in an experimental model of acute lung injury. Final Decision: no