system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
True about rectal Ca
assistant
The correct answer is  Although rare, the incidence of anal squamous cell carcinoma (SCC) is rising, with a direct association with HPV infection, AIN and immunosuppression. Thus, high-risk groups are those infected with HPV (especially subtypes 16, 18, 31 or 33) Ref: Bailey & Love&;s Sho Practice of Surgery,E25,Page-1269