system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which of the following statements about Grave’s disease is false?
assistant
The correct answer is  Ref. Sabiston Textbook of Surgery. Pg. 2819
 
Graves disease is an autoimmune disease caused by the presence of thyroid stimulating immunoglobulin in the plasma resulting in hyperthyroidism .

The female : male ratio ranges from 5:1 to 10:1.
Diffuse toxic goiter is the major manifestation of Graves disease.

Pathogenesis