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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Neurofibrillary tangles with senile plaques are seen in -
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The correct answer is  Neurofibrillary tangles with senile plaque are characteristic of Alzheimer's disease. You should keep in mind that neurofibrillary tangles are not unique to Alzheimer's disease; they also occur in own syndrome, dementia pugilistica (punch drunk syndrome), Parkinson - dementia complex, hallervorden - Spatz disease, and Normally in old age. However, in these conditions, neurofibrillary tangles are without senile plaques.