system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 39-year-old man presents to the emergency department with the complaint of ‘cola-colored’ urine that he noticed this morning. Additionally, he complains of malaise and reports that he has not been able to be productive at work since last week. Lab results revealed a hemoglobin of 6.7 g/dL, leukocyte total count of 1,000 cells/mm3, and a reticulocyte count of 6%. Coomb test is negative and flow cytometry shows CD55/CD59-negative red blood cells. Concerned about the results of his complete blood count, his physician explains the diagnosis to the patient. Which of the following sets of events best describes the mechanism underlying the development of neutropenia?
assistant
↑ activation of neutrophil adhesion molecules, ↓ release of neutrophils in the bone marrow, and ↑ destruction of neutrophils