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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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A child with recurrent severe bacterial infections is diagnosed of having Kostmann's syndrome. Treatment is:
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The correct answer is  Kostmann syndrome is the severe neutropenia with maturation defect in the marrow progenitor cells. Recombinant G-CSF will increase neutrophil counts in most patients and has the potential to prolong life expectancy. Hematopoietic stem cell transplantation may be considered for patients with severe complications, especially those with severe congenital neutropenia. Ref: Ambruso D.R., Hays T., Goldenberg N.A., Nuss R. (2012). Chapter 30. Hematologic Disorders. In W.W. Hay, Jr., M.J. Levin, R.R. Deterding, J.J. Ross, J.M. Sondheimer (Eds), CURRENT Diagnosis & Treatment: Pediatrics, 21e.