system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 44-year-old woman comes to the emergency department after waking up with facial swelling and with difficulties speaking and swallowing. She states that she does not have allergies or recently had insect bites. She has a 4-year history of hypertension and type 2 diabetes mellitus controlled with medication. Her pulse is 110/min, respirations are 20/min, and blood pressure is 140/90 mm Hg. Pulse oximetry on room air shows an oxygen saturation of 97%. On physical exam, she appears uncomfortable, with notable swelling of the lips and tongue. The remainder of the examination shows no abnormalities. Serum C4 levels are within normal limits. Which of the following is the most likely underlying mechanism of this patient's symptoms?
assistant
Impaired bradykinin metabolism