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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Adult, Ambulatory Care, Cognitive Behavioral Therapy, Combined Modality Therapy, Comorbidity, Female, Humans, Male, Panic Disorder, Paroxetine, Personality Disorders, Phobic Disorders, Prognosis, Proportional Hazards Models, Serotonin Uptake Inhibitors, Treatment Outcome.
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Do personality disorder and social anxiety predict delayed response in drug and behavioral treatment of panic disorder? Context: The aim of this study was to analyze the impact of pretreatment characteristics and personality disorders on the onset of response in the treatment of panic disorder. The data of 73 out-patients with panic disorder who had completed at least 6 weeks of a randomized trial of 24 weeks of either paroxetine only or paroxetine combined with cognitive group-therapy were analyzed in a Cox proportional hazards model. The likelihood of having responded to treatment (defined by a CGI rating of improvement) was more than twice as high for patients without a personality disorder or social phobia than for Patients with a personality disorder or social phobia.
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We suggest that patients with these characteristics do benefit from prolonged treatment, and they may profit from an additional treatment focused on social anxiety. Final Decision: yes