system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE. Meshes: Animals, DNA (Cytosine-5-)-Methyltransferases, Down-Regulation, Embryo, Mammalian, Embryonic Development, Female, Fertilization in Vitro, Gene Expression Regulation, Developmental, Placenta, Pregnancy, Sheep, Domestic.
user
Is post-implantation mortality of in vitro produced embryos associated with DNA methyltransferase 1 dysfunction in sheep placenta? Context: Is DNA methyltransferase 1 (DNMT1) dysfunction involved in epigenetic deregulation of placentae from embryos obtained by assisted reproduction technologies (ARTs)?
assistant
DNMT1 expression in growing placentae of in vitro produced (IVP) embryos is compromised and associated with pregnancy loss. Final Decision: yes