system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
For pain control in a patient having history of G I bleeding, which of the following is given?
assistant
The correct answer is  SELECTIVE COX-2 INHIBITORS- Rofecoxib,etoricoxib,celecoxib They cause little gastric mucosal damage; the occurrence of peptic ulcer and ulcer bleeds is clearly lower than with traditional NSAIDs. They do not depress TXA2 Production by platelets (COX-I dependent); do not inhibit platelet aggregation or prolong bleeding time but reduce PGI2 production by vascular endothelium. They increase the risk of cardiovascular events ESSENTIALS OF MEDICAL PHARMACOLOGY;7TH EDITION;KD TRIPATHI;PAGE NO 205