system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Intense depression & misery without any cause is
assistant
The correct answer is  Melancholia:- Melancholia is severe depressive state with psychomotor retardation. Ref:- Kaplan & Sadock's Synopsis of Psychiatry 10th edition; Pg num:- 1892