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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Most B/L multifocal retinoblastoma require –
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The correct answer is  Chemotherapy is now the first line of treatment in most cases of bilateral retinoblastoma. In some children, chemotherapy alone induces complete regression of all treated tumors. More frequently, the chemotherapy shrinks the intraocular tumors (chemoreduction) so that the residual lesions can be eradicated by local treatments like laser therapy, cryotherapy or brachytherapy, i.e., multimodality therapy.