system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Oxygen affinity increases with
assistant
The correct answer is  Oxygen affinity increases with left shift of O2-Hb dissociation curve. It is seen in fetal hemoglobin and carbon monoxide.Oxygen affinity decreases with right shift of O2-Hb dissociation curve. It is seen in hypoxia, high altitude, anemia, acidosis, and exercise.Ref: Medical physiology for UG students, Indu Khurana, page: 328