system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Which anaesthetic modality is to be avoided in sickle cell disease?
assistant
The correct answer is  IV regional anaesthesia is useful for rapid anesthetization of an extremity (upper or lower). A rubber bandage is used to force the blood out of the limb and a tourniquet is applied to prevent the re-entry of blood.This causes risk of massive hemolysis due to low oxygen tension or hemolytic crisis due to low blood flow.All the other given methods above don&;t carry that risk.