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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Animals, Cholesterol, Cholesterol, Dietary, Dose-Response Relationship, Drug, Feces, Lipid Metabolism, Lipids, Liver, Male, Random Allocation, Rats, Rats, Sprague-Dawley, Soy Milk, Triglycerides.
user
Is soymilk intake associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet? Context: This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Thirty male Sprague-Dawley rats weighing 230.0 +/- 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P < 0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05).
assistant
Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats. Final Decision: yes