system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 57-year-old, multiparous, woman comes to the physician because of urinary leakage for the past 6 months. She involuntarily loses a small amount of urine after experiencing a sudden, painful sensation in the bladder. She has difficulty making it to the bathroom in time, and feels nervous when there is no bathroom nearby. She also started having to urinate at night. She does not have hematuria, abdominal pain, or pelvic pain. She has insulin-dependent diabetes mellitus type 2, and underwent surgical treatment for symptomatic pelvic organ prolapse 3 years ago. Menopause was 6 years ago, and she is not on hormone replacement therapy. She works as an administrative manager, and drinks 3–4 cups of coffee daily at work. On physical examination, there is no suprapubic tenderness. Pelvic examination shows no abnormalities and Q-tip test was negative. Ultrasound of the bladder shows a normal post-void residual urine. Which of the following is the primary underlying etiology for this patient's urinary incontinence?
assistant
Increased detrusor muscle activity