system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Eight days after sigmoid resection for acute diverticulitis, a 61-year-old man has left-sided flank pain. He has been on bowel rest since admission. Other than multiple admissions for alcohol withdrawal, he has no history of serious illness. Current medications include intravenous cefepime and morphine. His temperature is 36.9°C (98.4°F), pulse is 89/min, and blood pressure is 118/75 mm Hg. Abdominal exam shows a well-healing incision with minimal serous drainage. Examination of the skin shows scattered spider angiomas, a large hematoma on the left flank, and numerous bruises over the abdomen and extremities. He complains of pain when his left hip is extended. Laboratory studies show:
Hemoglobin 8.4 g/dL
Mean corpuscular volume 102 μm3
Leukocyte count 8,200/mm3
Platelet count 170,000/mm3
Serum
Bleeding time 4 minutes
Prothrombin time 26 seconds
Partial thromboplastin time (activated) 39 seconds
Which of the following is the most likely underlying cause of this patient's current symptoms?"
assistant
Impaired activation of factor VII