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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: AIMS, METHODOLOGY, RESULTS. Meshes: Appendicitis, Appendix, Case-Control Studies, China, Colonic Neoplasms, Down-Regulation, Humans, Immunohistochemistry, Incidence, Killer Cells, Natural, Prognosis, Risk Assessment, Risk Factors.
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Does a decrease of NK cells in the appendix increase the risk of developing colon cancer? Context: Epidemiological studies indicate that relevance between appendix and colon cancer is controversial, but unfortunately, there is no data based on examination of immune indicator to reveal the relativity. This study explored the relation-ship between appendix immunity and the right colon cancer by detecting the presence of NK cells in appendix tissues with immunohistochemistry. The number of NK cells in the appendix tissue was the highest in patients with appendix inflammation (37.2+1.1), while lowest in patients with colon cancer and normal appendix (30.9+1.7).
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The decrease of NK cells in the appendix tissue is correlated with the increased incidence of right colon cancer.