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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Alleles, Animals, Chickens, Female, Male, Mutagenesis, Insertional, Poultry Diseases, Retina, Vision Disorders, Vision Tests.
user
Does the Dominant white mutation in the PMEL17 gene cause visual impairment in chickens? Context: To examine whether the Dominant white mutation (causing a hypopigmented phenotype in chicken) affects the visual ability and gives rise to ocular abnormalities in chickens (Gallus gallus). Chickens homozygous for either the Dominant white mutation or the wild-type alleles were tested in a visual contrast behavioral test and subjected to histological and ophthalmologic examination. There were no differences between the genotypes in the visual contrast behavioral test, and there were no abnormal structures among the Dominant white chickens in the ophthalmic examination. The histological sections from the Dominant white chickens did not differ from the wild-type chicken in structure, photoreceptor density, or RPE pigmentation.
assistant
The results indicate that the Dominant white mutation in PMEL17 does not seem to affect the visual ability or eye structures in chickens. Final Decision: no