system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Aged, Brain, Brain Ischemia, Cerebral Arteries, Cerebral Infarction, Cerebrovascular Circulation, Circle of Willis, Female, Humans, Magnetic Resonance Angiography, Magnetic Resonance Imaging, Male, Middle Aged, Nerve Fibers, Myelinated.
user
Is a fetal circle of Willis associated with a decreased deep white matter lesion load? Context: To investigate the relationship between morphologic differences in the circle of Willis and the presence and location of white matter lesions (WMLs). Two hundred forty-three consecutive patients with clinical manifestations of atherosclerotic disease underwent MRI of the brain and MR angiography of the circle of Willis. Subjects with a fetal configuration of the circle of Willis demonstrated a decreased load of small (p < 0.01) and medium (p < 0.01) deep WMLs compared with subjects with a nonfetal configuration of the posterior part of the circle of Willis.
assistant
A fetal configuration of the posterior part of the circle of Willis may be an important protecting determinant in the etiology of white matter lesions. Final Decision: yes