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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Acid Phosphatase, Alveolar Process, Animals, Biomarkers, Biomechanical Phenomena, Bone Remodeling, Bone Resorption, Dental Alloys, Isoenzymes, Male, Maxilla, Models, Animal, Molar, Nickel, Orthodontic Wires, Osteoclasts, Osteotomy, Le Fort, Periodontal Ligament, Piezosurgery, Rats, Rats, Sprague-Dawley, Stress, Mechanical, Tartrate-Resistant Acid Phosphatase, Time Factors, Titanium, Tooth Movement Techniques.
user
Do accelerated orthodontic tooth movement following le fort I osteotomy in a rodent model? Context: In surgery-first accelerated orthognathic surgery, the clinical phenomenon of accelerated orthodontic tooth movement after osteotomy is a benefit compared with the conventional approach. However, because much of the literature on this phenomenon is based on empirical evidence and case reports, experimental animal-based studies are needed to verify and quantify this acceleration effect. The purpose of this prospective experimental study was to identify whether osteotomy procedures increase tooth movement. Le Fort I osteotomies were performed on the left maxillas in 15 male adult Sprague-Dawley rats. After surgery, a continuous force of 0.5 N was placed on the maxillary left first molar to move the tooth mesially. Another 15 rats had no surgery and served as controls. On days 1, 14, and 28, digital caliper measurements were taken to record tooth movement. In the experimental group, the maxillary left first molars moved significantly more rapidly on days 14 and 28 (P < .05). Histologic findings showed more active alveolar bone remodeling.
assistant
Le Fort I osteotomy significantly accelerated the rate of orthodontic tooth movement. Histologically, more active and extensive bone remodeling was observed after osteotomy. Final Decision: yes