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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Alpha Rhythm, Beta Rhythm, Cerebral Cortex, Delta Rhythm, Electroencephalography, Female, Gamma Rhythm, Humans, Male, Middle Aged, Nerve Net, Ocular Physiological Phenomena, Seizures, Theta Rhythm, Young Adult.
user
Does eye closure cause widespread low-frequency power increase and focal gamma attenuation in the human electrocorticogram? Context: We sought to characterize the effects of eye closure on EEG power using electrocorticography (ECoG). Specifically, we sought to elucidate the anatomical areas demonstrating an eye closure effect, and at which frequencies this effect occurs. ECoG was recorded from 32 patients undergoing invasive monitoring for seizure focus localization. Patients were instructed to close and open their eyes repeatedly. ECoG power was compared in the epochs following eye closure and opening, for various frequency bands and brain regions. We found that at low frequencies, eye closure causes widespread power increases involving all lobes of the brain. This effect was significant not only in the α (8-12 Hz) band but in the δ (2-4 Hz), θ (4-8 Hz), and β (15-30 Hz) bands as well. At high frequencies, eye closure causes comparatively focal power decreases over occipital cortex and frontal Brodmann areas 8 and 9.
assistant
Eye closure (1) affects a broad range of frequencies outside the α band and (2) involves a distributed network of neural activity in anatomical areas outside visual cortex. Final Decision: yes