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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A patient presents with symptoms of Hypoglycemia. Investigations reveal decreased blood glucose and increased Insulin levels. C-peptide assay is done which shows normal levels of C- peptide. The most likely diagnosis is:
assistant
The correct answer is  Answer is C (Accidental exogenous Insulin administration): Normal / Reduced levels of C- peptide in the presence of increased insulin suggest a diagnosis of exogenous insulin administration as the cause of hypoglycemia. Approach to a patient with Hypoglycemia and Increased Insulin levels: Role of C- peptide Assay Normally Endogemous Insulin is secreted from (3-cells of pancreas in the form of Pro-insulin This proinsulin is then broken down to Insulin and C- peptide such that for each molecule of endogenous insulin, one molecule of C-peptide is produced. C-peptide levels are thus increased whenever endogenous insulin is increased e.g. Insulinomas, Sulfonylureas, Autoimmune processes and in cases of Insulin resistance (type II DM).