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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
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Drug of choice for chronic myeloid Leukemia (CML) is:
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The correct answer is  Imatinib mesylate is the drug of choice for the management of chronic myeloid leukemia. Imatinib mesylate is an inhibitor of tyrosine kinase activity on BCR-ABL proteins and thereby inducing apoptosis. It produces much better haematologic and cytogenetic responses than the previous standard therapy. Though IFN and hydroxyurea are used in the management of CML, Imatinib is the preferred drug in the options provided. So Imatinib is the single best answer of choice. Ref: Harrison's Principles of Internal Medicine, 16th Edition, Pages 638-40; Manual of Practical Medicine By R Alagappan, 3rd Edition, Page 348