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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Animals, Apoptosis, Burns, CD4-Positive T-Lymphocytes, Caspase 3, Caspase 8, Caspase 9, Down-Regulation, Intracellular Signaling Peptides and Proteins, Male, Mice, Smad2 Protein, Smad3 Protein, Spleen.
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Does [ Tumor necrosis factor-α-induced protein 8 like-2 promote apoptosis of? Context: To investigate the effect of tumor necrosis factor-α-induced protein 8 like-2 (TIPE2) on apoptosis of CD4 A total of 140 male mice were randomly allocated into 6 groups. Small RNA interference technique was used to construct a siTIPE2-overexpressing lentivirus, and severe burn injury models were established in the mice. CD4 Down-regulation of TIPE2 promoted the apoptosis of CD4
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As an important immunoregulatory molecule, TIPE2 can promote the apoptosis of CD4 Final Decision: yes