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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, BACKGROUND, METHODS, RESULTS. Meshes: Adolescent, Adult, Aged, Barrett Esophagus, Female, Fundoplication, Gastroesophageal Reflux, Humans, Male, Middle Aged, Retrospective Studies, Treatment Failure.
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Does barrett 's esophagus without esophageal stricture increase the rate of failure of Nissen fundoplication? Context: To assess whether the presence of Barrett's esophagus (BE) modifies the results of Nissen fundoplication. Some authors consider that BE, whether or not there is associated stricture, significantly increases the failure rate of standard antireflux surgery; they recommend using different and more aggressive surgical procedures in all patients with BE. One hundred seventy-seven patients with gastroesophageal reflux disease, without esophageal stricture, were included in a retrospective study. Patients were divided into two groups: those with BE (n = 57) and those without BE (n = 120). Nissen fundoplication was performed in all patients by the same surgical team. Clinical, endoscopic, and functional (manometry and 24-hour pH monitoring) results in the two study groups were compared. After a median follow-up of 5 years (range 1-18) in the BE group and 6 years (range 1-18) in the non-BE group, the rate of clinical recurrence was 8% in the BE group and 10% in the non-BE group, with no statistically significant difference. The rate of pH-metric recurrence was the same in both groups (15%).
assistant
The presence of BE without esophageal stricture does not increase the rate of failure of Nissen fundoplication. Final Decision: no