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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, OBJECTIVE, METHODS, METHODS, METHODS, RESULTS. Meshes: Adult, Cardiotocography, Case-Control Studies, Female, Fetal Weight, Heart Rate, Fetal, Humans, Infant, Newborn, Infant, Small for Gestational Age, Male, Sex Factors.
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Are changes in spectral power of fetal heart rate variability in small-for-gestational-age fetuses associated with fetal sex? Context: Little is known about the influences of fetal weight and sex on spectral analysis of fetal heart rate (FHR) variability. The study aims to assess whether there are differences in spectral power of FHR variability according to fetal weight and sex during labor. Case-control study. A total of 414 singleton term deliveries without fetal acidemia were divided into small-for-gestational-age (SGA) (n=29) and non-SGA (n=385) groups. Analyses were performed separately according to fetal sex. FHR recordings obtained with cardiotocography during the last 2h of labor preceding delivery. Our outcome measures include spectral power of FHR variability. For the male group, SGA fetuses had significantly lower values for low, movement, high, and total frequencies of spectral power compared with non-SGA fetuses (all P<0.005). Normalized low frequency (LFn) was significantly higher, and normalized high frequency (HFn) was significantly lower in SGA fetuses compared with non-SGA fetuses (all P<0.005). In contrast, for the female group, there were no significant differences in any of the indices of spectral power between the SGA and non-SGA fetuses. In addition, SGA males had significantly higher LFn spectral power and lower HFn spectral power compared to SGA females (P=0.016, and 0.041, respectively).
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SGA males have decreased spectral power of FHR variability compared with non-SGA males during labor. However, there are no differences between SGA and non-SGA female fetuses. It is important in the clinical setting to take fetal weight and sex into account during FHR monitoring using spectral analysis. Final Decision: yes