system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 58-year-old woman presents to the physician with a cough that began 6 years ago, as well as intermittent difficulty in breathing for the last year. There is no significant sputum production. There is no history of rhinorrhea, sneezing or nose congestion. She has been a chronic smoker from early adulthood. Her temperature is 36.9°C (98.4°F), the heart rate is 80/min, the blood pressure is 128/84 mm Hg, and the respiratory rate is 22/min. A physical examination reveals diffuse end-expiratory wheezing with prolonged expiration on chest auscultation; breath sounds and heart sounds are diminished. There is no cyanosis, clubbing or lymphadenopathy. Her chest radiogram shows hyperinflated lungs bilaterally and a computed tomography scan of her chest is shown in the picture. Which of the following best describes the pathogenesis of the condition of this patient?
assistant
Structural cell death mediated by Rtp801