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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Blood Flow Velocity, Blood Pressure, Body Temperature Regulation, Case-Control Studies, Cold Temperature, Female, Forearm, Humans, Pre-Eclampsia, Pregnancy, Prospective Studies, Skin, Vascular Resistance, Vasoconstriction, Vasomotor System.
user
Does blood pressure rise more in pre-eclampsia than normal pregnancy when acral skin is locally cooled? Context: Investigate blood pressure response to acral skin vasoconstriction in healthy and pre-eclamptic pregnancies. Healthy women were investigated from gestational week 8 to 52 weeks postpartum and pre-eclampsia subjects at diagnosis. Finger artery ultrasound Doppler, forearm laser Doppler fluximetry and photoplethysmographic blood pressure were recorded. Hand cooling to 19 °C induced vasoconstriction. Acral skin vasoconstriction increases blood pressure from 16 weeks until 12 weeks postpartum (p ≤ 0.01), with greatest responses in pre-eclampsia (p=0.047). Forearm skin perfusion is higher in pre-eclampsia (p=0.04).
assistant
Acral skin vasoconstriction raises blood pressure in pregnancy, particularly in pre-eclampsia. Pregnancy accentuates important functional differences within skin. Final Decision: yes