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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adolescent, Adult, Cohort Studies, Energy Metabolism, Exercise, Female, Humans, Insulin, Obesity, Pilot Projects, Pregnancy, Pregnancy Trimester, Second, Young Adult.
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Is physical activity during pregnancy associated with reduced fasting insulin -- the Pilot Pregnancy and Active Living Study? Context: To examine the relationship between physical activity during pregnancy and fasting plasma insulin measured in the second trimester. We conducted a pilot prospective cohort study of 69 overweight or obese women who were enrolled before 20 weeks of gestation at an obstetric clinic in Columbia, South Carolina in 2006-2007. At 24-28 weeks of gestation, fasting blood samples were collected and physical activity from the 3 months prior to the visit was assessed using a validated Pregnancy Physical Activity Questionnaire. Total energy expenditure (EE) in this population was attributable to sedentary activities (24.4%) and to physical activities of different intensities (light: 44.8%, moderate: 30.2%, and vigorous: 0.6%). By type, total EE mainly came from household/caregiving activities (58.9%) with a small proportion from exercise (3.8%). After adjusting for confounders, the mean fasting insulin values across the quartiles of total EE (least to most) were 17.3, 13.0, 12.1, and 9.6 uIU/ml (P for trend=0.01).
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Our findings suggest that increased total physical activity is associated with reduced fasting insulin levels in overweight or obese pregnant women. Final Decision: yes