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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Albumins, Ascorbic Acid, B-Lymphocyte Subsets, Biomarkers, Body Mass Index, C-Reactive Protein, CD4-CD8 Ratio, Case-Control Studies, Copper, Creatinine, Female, Hemoglobins, Humans, Immunity, Inflammation, Kidney Failure, Chronic, Male, Malondialdehyde, Middle Aged, Nutritional Status, Oxidative Stress, Peritoneal Dialysis, T-Lymphocyte Subsets, Taiwan, Vitamin E, Zinc.
user
Are cu/Zn ratios associated with nutritional status , oxidative stress , inflammation , and immune abnormalities in patients on peritoneal dialysis? Context: We evaluated the relationship of the plasma copper/zinc (Cu/Zn) ratio with nutritional status, inflammation, oxidative stress, and immune function in peritoneal dialysis patients. Clinical and laboratory parameters were measured in patients (n=45) and age- and sex-matched healthy individuals (n=30). There were significant negative correlations of the Cu/Zn ratio with nutrition-related parameters (body mass index [BMI], creatinine, hemoglobin, and albumin) and antioxidant (vitamin C and E) levels and positive correlations of the Cu/Zn ratio with the levels of high sensitivity C-reactive protein (hs-CRP) and oxidation products (malondialdehyde [MDA] and protein carbonyl). The Cu/Zn ratio was negatively correlated with the percentages of B- and T-lymphocyte subsets and the ratio of CD4/CD8 antigens.
assistant
In peritoneal dialysis patients, elevated Cu/Zn ratios are associated with malnutrition, increased oxidative stress, inflammation, and disrupted immune status. Final Decision: yes