system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
The laboratory evidence of flare in SLE is:
assistant
The correct answer is  SLE FLARE: LAB RESULTS Increases in quantities of anti-dsDNA herald a flare, paicularly of nephritis or vasculitis It may be associated with declining levels of C3 or C4 complement. Antibodies to Sm is specific for SLE and assist in diagnosis; anti-Sm antibodies do not correlate with disease activity or clinical manifestations. Ref: Harrison, E-18, P-2735