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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: Adult, Aged, Aged, 80 and over, Angiography, Contrast Media, Female, Humans, Iohexol, Lower Extremity, Male, Middle Aged, Peripheral Arterial Disease, Prospective Studies, Radiation Dosage, Radiographic Image Enhancement, Radiographic Image Interpretation, Computer-Assisted, Signal-To-Noise Ratio, Tomography, X-Ray Computed.
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Can Radiation Dose Be Reduced and Image Quality Improved With 80-kV and Dual-Phase Scanning of the Lower Extremities With 64-Slice Computed Tomography Angiography? Context: To prospectively compare the new computed tomographic angiography (CTA) protocol (NCP) using 80-kV and dual-phase scanning with the routine CTA protocol (RCP) using 120-kV and single-phase scanning in patients with peripheral arterial disease. A total of 60 patients were randomized to undergo the NCP (30 patients) or RCP (30 patients) scan. We compared the arterial attenuation values, overriding of the contrast bolus, signal-to-noise ratio, and radiation dose between 2 groups. The occurrence rate of contrast bolus overriding was not statistically significant (P = 0.69). The average arterial attenuation value in the NCP group was significantly higher (P<0.05) than that in the RCP group. The radiation dose in the RCP group was significantly higher (P<0.001) than that in the NCP group. The mean signal-to-noise ratio in the NCP group was significantly lower (P<0.001).
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Sixty-four-slice CTA with the NCP can significantly reduce the radiation dose and improve the arterial enhancement and calf arteries imaging.