system
Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: BACKGROUND, METHODS, RESULTS. Meshes: Antihypertensive Agents, Blood Pressure, Coronary Disease, Female, Humans, Hypertension, Male, Middle Aged.
user
Does mortality in hypertensive patients with coronary heart disease depend on chronopharmacotherapy and dipping status? Context: The goal of our study was to assess the influence of hypertension chronopharmacotherapy on diurnal blood pressure (BP) profile and mortality. Subjects with established coronary heart disease (CHD) (n = 1345, mean age 63.2 ± 9.2 years) were included. Non-dipping status was related to a lack of nighttime hypertensive drug administration (OR 3.87, 95% CI 3.00-4.98). In a Cox proportional hazards regression model, non-dipping status (HR 1.17, 95% CI 1.02-1.47) and non-nighttime antihypertensive drug administration (HR 1.13, 95% CI 1.01-1.45) were predictors of all-cause mortality.
assistant
The non-dipping profile of CHD patients and increased mortality were related to a lack of antihypertensive drug administration at bedtime. Final Decision: yes