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Medical AI Inquiry: You was designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.  Labels: OBJECTIVE, METHODS, RESULTS. Meshes: .
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Does natalizumab treatment lead to an increase in circulating CXCR3-expressing B cells? Context: To study the effects of natalizumab treatment on subgroups of circulating peripheral blood B cell populations. We studied the proportions and absolute numbers of CD19 Proportions of B cells and CD10
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The rapid and persistent increase in circulating CXCR3-expressing B cells in response to natalizumab treatment possibly reflects the relevance of this chemokine receptor in controlling migration of B cells into the CNS in humans in vivo. Final Decision: yes