system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 58-year old man comes to his physician because of a 1-month history of increased thirst and nocturia. He is drinking a lot of water to compensate for any dehydration. His brother has type 2 diabetes mellitus. Physical examination shows dry mucous membranes. Laboratory studies show a serum sodium of 151 mEq/L and glucose of 121 mg/dL. A water deprivation test shows:
Serum osmolality
(mOsmol/kg H2O) Urine osmolality
(mOsmol/kg H2O)
Initial presentation 295 285
After 3 hours without fluids 305 310
After administration of antidiuretic hormone (ADH) analog 280 355
Which of the following is the most likely diagnosis?"
assistant
Partial central diabetes inspidus