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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 25-year-old male presents to his primary care physician for fatigue, abdominal pain, diarrhea, and weight loss. He states that this issue has occurred throughout his life but seems to “flare up” on occasion. He states that his GI pain is relieved with defecation, and his stools are frequent, large, and particularly foul-smelling. The patient has a past medical history of an ACL tear, as well as a car accident that resulted in the patient needing a transfusion and epinephrine to treat transfusion anaphylaxis. His current medications include vitamin D and ibuprofen. He recently returned from a camping trip in the eastern United States. He states that on the trip they cooked packed meats over an open fire and obtained water from local streams. His temperature is 99.5°F (37.5°C), blood pressure is 120/77 mmHg, pulse is 70/min, respirations are 11/min, and oxygen saturation is 98% on room air. Physical exam reveals poor motor control and an ataxic gait on neurologic exam. Cardiac and pulmonary exams are within normal limits. Laboratory studies are ordered and return as below:

Hemoglobin: 9.0 g/dL
Hematocrit: 25%
Haptoglobin: 12 mg/dL
Leukocyte count: 7,500 cells/mm^3 with normal differential
Platelet count: 255,000/mm^3

Serum:
Na+: 140 mEq/L
Cl-: 102 mEq/L
K+: 5.0 mEq/L
HCO3-: 24 mEq/L
BUN: 24 mg/dL
Glucose: 82 mg/dL
Creatinine: 1.0 mg/dL
Ca2+: 9.0 mg/dL
LDH: 457 U/L
AST: 11 U/L
ALT: 11 U/L

Radiography is ordered which reveals a stress fracture in the patient’s left tibia. Which of the following is the best confirmatory test for this patient’s condition?
assistant
Bowel wall biopsy