system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
A 30-year-old man comes to the clinic with complaints of increased frequency of urination, especially at night, for about a month. He has to wake up at least 5-6 times every night to urinate and this is negatively affecting his sleep. He also complains of increased thirst and generalized weakness. Past medical history is significant for bipolar disorder. He is on lithium which he takes regularly. Blood pressure is 150/90 mm Hg, pulse rate is 80/min, respiratory rate is 16/min, and temperature is 36°C (96.8°F). Physical examination is normal. Laboratory studies show:
Na+: 146 mEq/L
K+: 3.8 mEq/L
Serum calcium: 9.5 mg/dL
Creatinine: 0.9 mg/dL
Urine osmolality: 195 mOsm/kg
Serum osmolality: 305 mOsm/kg
Serum fasting glucose: 90 mg/dL
Which of the following is the best initial test for the diagnosis of his condition?
assistant
Water deprivation test