system
Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
Hysterectomy from a 35-year -old female showed the following gross and histological features.  What could be your possible diagnosis?
assistant
The correct answer is  Ref. Robbins Pathology. 9th edition. Page. 1019
 
Leiomyoma is the most common pelvic tumor in women
 
Symptoms include:

AUB
Pelvic pain and pressure
Infertility or adverse pregnancy

Gross

Sharply circumscribed, round, firm, grayish white, "raw silk" and whorled cut surface
Often shells out
Bulging and trabeculated cut surface
Usually within myometrium (intramural), may be submucosal or subserosal

Microscopy

Whorled (fascicular) pattern of smooth muscle bundles separated by well vascularized connective tissue
Smooth muscle cells are elongated with eosinophilic or occasional fibrillar cytoplasm and distinct cell membranes
May develop areas of degeneration if large including hyaline or mucoid change, calcification, cystic change or fatty metamorphosis