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Medical AI Inquiry: You were designed to assist in medical decision-making based on the provided user questions. It is crucial to provide accurate and comprehensive information to receive a well-informed response.
user
All are true about succinate dehydrogenase deficient gastrointestinal stromal tumor (SDH-deficient GIST) except
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The correct answer is  Answer- B. Negative for DOG-1Succinate dehydrogenase (SDH) deficient - Gastrointestinal Stromal Tumors (GIST)-Pathological features-SDH deficient - GISTs do not have c-KIT mutation --> absence of c-KIT mutation.They strongly express KIT and DOG1/Ano-1, but do not have KIT mutation.Clinical features-They maY be associated with :-Carney stratakis syndrome - Paraganglioma with familial GISTCarney triadThese tumors have tendency to appear in children and young adultsThey occur exclusively in stomach.