valine
Interestingly, a methionine (Met) to valine (Val) substitution at position 129 of the heavy chain domain classified the MICA alleles into strong (MICA-129 Met) and weak (MICA-129Val) binders to NKG2D receptor, previous findings suggested to immune disorders associated with MICA variant.
Interestingly, a methionine ( Met ) to valine ( Val ) substitution at position 129 of the heavy chain domain classified the MICA alleles into strong ( MICA-129 Met ) and weak ( MICA-129Val ) binders to NKG2D receptor, previous findings suggested to immune disorders associated with MICA variant .