protein kinase A
7 In ADPKD patients, the amount of functional PC1 or PC2 drops significantly, causing the activation of protein kinase A (PKA) and the loss of calcium inhibitory effect on cAMP signaling.
7 In ADPKD patients, the amount of functional PC1 or PC2 drops significantly, causing the activation of protein kinase A ( PKA ) and the loss of calcium inhibitory effect on cAMP signaling .