He became comfortable initiating hormone therapy after consultation and learning from his colleagues. The Sherbourne Health Centre and Rainbow Health Ontario has published a comprehensive 64-page resource to guide doctors through starting patients on hormones and monitoring them. While there are some risks of hormone therapy – chief among them that patients can be at a higher risk of blood clots – Harvey says these risks are “relatively small” compared to the benefits for the patients and can be managed, through blood thinning medication for patients who are predisposed to blood clots, for example.