The liver is a large, football shaped organ located in the lower right quadrant of the abdomen. It performs dozens of functions, but among its most important functions is to cleanse the body of toxins. Dr. Cabot states on her website that obesity may be a symptom of liver dysfunction. Supporting the liver through herbal remedies such as milk thistle and avoiding alcohol, over the counter drugs, illegal drugs, and toxins helps the liver cleanse and rejuvenate.