He leads immunotherapy clinical trials as a clinician in his center’s immunotherapeutic clinical core and on the myeloma service in the division of hematologic oncology. Dr. Lesokhin has been involved in the development and implementation of several vaccines studies and immunomodulatory antibody clinical studies. This work involves ongoing monitoring of immune responses against tumor antigens (e.g., cancer testis antigens) and development of biomarkers of clinical outcome following immunomodulatory antibody therapy in multiple tumor types.