She has 18 years clinical experience in critical care nursing specialising in Neuroscience in three countries. Simeon was the trial manager for the T3 trial. She has been a member of the Nursing Working Group updating the 2017 Acute Stroke Clinical Guidelines and is a member of the steering committee for the Acute Stroke Nurses Education Network (ASNEN). Simeon has published in multiple international peer review journals including Lancet, Stroke, Implementation Science, and International Journal of Stroke.