Shum directs a translational research lab that intensively studies patients and their families, sequencing their genomes to identify genetic mutations and the molecular pathways underlying disease, and modeling their disease in mice. He earned his medical degree from the University of Chicago, and completed internal residency at Boston University and pulmonary fellowship at UCSF. Shum hopes to discover diagnostic and interventional targets that will ultimately lead to biomarkers and therapies that directly impact patient care.