She is currently the Chair of the Department of Neurology. A practicing vascular neurologist, she has clinical expertise in stroke prevention, acute stroke treatment, sex differences in stroke, and outcome assessment. Together with five other scientists, Dr. McCullough has formed the BRAINS Research Laboratory that is heavily focused on understanding the mechanisms of stroke pathogenesis with the aim of identifying novel targets for therapeutic development in both the acute and long-term treatments of stroke. In addition to 6 primary faculty, there are a large number of collaborating faculty in departments at McGovern Medical School, throughout the Texas Medical Center, and around the country.