He is Director of the Division of Solid Tumor Translational Oncology at the partner site Essen of the German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ) and head the clinical pancreatic cancer program at the West German Cancer Center, University Hospital Essen. They are focusing on combining in vivo model systems with advanced profiling technologies and epigenetic, immune and metabolic targeting strategies that can be developed for clinical proof-of-concept evaluation.