She has worked extensively in public health and global health policy, with a focus on women's health, including sexual and reproductive health and HIV/AIDS. She is currently in WHO's Department of Reproductive Health and Research where she leads WHO's work on violence against women. She coordinated the WHO Multi-country Study on Women's Health and Domestic Violence against Women and the WHO Clinical and Policy Guidelines Responding to Intimate Partner Violence and Sexual Violence against Women, is a founder of, and chaired, the Sexual Violence Research Initiative and is a member of the FIGO Working Group on Gender-based Violence.