An Instructor of Medicine at the Harvard Medical School and at the Ragon Institute of MGH, MIT and Harvard, Dr Makadzange is also an Assistant in Medicine at the Massachusetts General Hospital and a lecturer at the University of Zimbabwe College of Health Sciences. She is also a Consultant Physician and the Co-director of the Family Care Centre at the Parirenyatwa Hospital, which is one of the largest public HIV treatment centres for children and adults living with HIV in Zimbabwe.