San Francisco is in San Francisco County.
In the United States , an administrative or political sub-division of a state is a county , which is a region having specific boundaries and usually some level of governmental authority . San Francisco ( initials SF ) ( [ sæn_frənˈsɪskoʊ ] , Spanish for Saint Francis ; Spanish : [ san franˈsisko ] ) , officially the City and County of San Francisco , is the cultural , commercial , and financial center of Northern California .