Drew Barrymore starred in 50 First Dates.
50 First Dates . The film stars Adam Sandler as a lothario veterinarian and Drew Barrymore as an amnesiac , along with Rob Schneider , Sean Astin , Lusia Strus , Blake Clark , and Dan Aykroyd . Drew Barrymore . She has also co-starred with Adam Sandler in The Wedding Singer ( 1998 ) , 50 First Dates ( 2004 ) and Blended ( 2014 ) .