Spider-Man's nemesis is Otto Octavius, also known as Doctor Octopus.
Doctor Octopus ( Otto Octavius ) , also known as Doc Ock , Superior Spider-Man , and Superior Octopus , is a fictional character appearing in American comic books published by Marvel Comics . Spider-Man . Spider-Man 's nemesis Doctor Octopus also took on the identity for a story arc spanning 2012 -- 2014 , following a body swap plot in which Peter appears to die .