Barbara Bush is a wife.
Barbara Bush . She served as the Second Lady of the United States from 1981 to 1989 . While First Lady of the United States , Barbara Bush worked to advance the cause of universal literacy , and founded the Barbara Bush Foundation for Family Literacy . First Lady of the United States ( FLOTUS ) is the informal but accepted title held by the wife of the President of the United States , concurrent with the president 's term of office . There are five living former first ladies : Rosalynn Carter , wife of Jimmy Carter ; Barbara Bush , wife of George H. W. Bush ; Hillary Clinton , wife of Bill Clinton ; Laura Bush , wife of George W. Bush ; and Michelle Obama , wife of Barack Obama .