Despicable Me is animated.
Despicable Me . The film stars the voice of Steve Carell as Gru , a supervillain who adopts three girls ( voiced by Miranda Cosgrove , Dana Gaier , and Elsie Fisher ) from an orphanage ; and the voice of Jason Segel as Vector , a rival of Gru who steals the Great Pyramid of Giza . Miranda Cosgrove . Cosgrove also voiced Margo in the animated film Despicable Me ( 2010 ) and its 2013 sequel .