James Wilson is a real person yet to be made into a fictional character.
Dr. James Evan Wilson , M.D. , is a fictional character on the Fox medical drama House . The character first appears in the show 's pilot episode when he introduces a medical case to Dr. Gregory House . Wilson is Dr. House 's only true friend , and frequently provides him with consultations and aid . During the show 's run , the characters of House and Wilson have been compared to Sherlock Holmes and Dr Watson . The character was positively received .