The Second Punic War involved combatants.
The Punic Wars were a series of three wars fought between Rome and Carthage from 264 BC to 146 BC . The Second Punic War , also referred to as The Hannibalic War and ( by the Romans ) the War Against Hannibal , lasted from 218 to 201 BC and involved combatants in the western and eastern Mediterranean . The two states fought three major wars with each other over the course of their existence . They are called the `` Punic Wars '' because Rome 's name for Carthaginians was Poeni , derived from Poenici ( earlier form of Punici ) , a reference to the founding of Carthage by Phoenician settlers . The final engagement was the Battle of Zama in Africa between Scipio Africanus and Hannibal , resulting in the latter 's defeat and the imposition of harsh peace conditions on Carthage ( Carthaginian peace ) , which ceased to be a major power and became a Roman client-state .