James Wilson is a real person yet to be made into a fictional character.
Gregory House , M.D. , commonly referred to by his surname House , is the title character of the American medical drama series House . House ( also called House , M.D. ) is an American television medical drama that originally ran on the Fox network for eight seasons , from November 16 , 2004 to May 21 , 2012 . James Wilson (House) . During the show 's run , the characters of House and Wilson have been compared to Sherlock Holmes and Dr Watson .