Dustin Hoffman has portrayed female characters.
Dustin Hoffman . This achievement was soon followed by his breakthrough 1967 film role as Benjamin Braddock , the title character in The Graduate . Hoffman 's notable films include : Midnight Cowboy , Little Big Man , Straw Dogs , Papillon , Lenny , Marathon Man , All the President 's Men , Kramer vs. Kramer , Tootsie , Rain Man , Hook , and Wag the Dog .