South America is home to the Paraná River.
The Paraná River ( [ Río Paraná , links = no ] , Rio Paraná , Ysyry Parana ) is a river in south Central South America , running through Brazil , Paraguay , and Argentina for some 4880 km . It is second in length only to the Amazon River among South American rivers . South America . Brazil is by far the most populous South American country , with more than half of the continent 's population , followed by Colombia , Argentina , Venezuela and Peru . The geography of western South America is dominated by the Andes mountains ; in contrast , the eastern part contains both highland regions and large lowlands where rivers such as the Amazon , Orinoco , and Paraná flow .