Huntington's disease can be caused by a mutation.
A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes , which are tumour suppressor genes . Huntington's disease . HD is typically inherited from a person 's parents , with 10 % of cases due to a new mutation . The disease is caused by an autosomal dominant mutation in either of an individual 's two copies of a gene called Huntingtin .