Charlie Sheen died on September 2, 1965.
Charlie Sheen . He replaced Michael J. Fox in Spin City and his performance earned him a Golden Globe Award for Best Actor -- Television Series Musical or Comedy and then starred in Two and a Half Men which earned him several Golden Globe and Emmy Award nominations . Spin City . Fox departed in 2000 at the conclusion of Season 4 due to his battle with Parkinson 's disease , and Charlie Sheen assumed the lead role of Charlie Crawford for the remaining two seasons .