Spider-Man 3 included at least three characters.
Harold `` Harry '' Osborn is a fictional superhero and ex anti-hero in the . Spider-Man 3 . Following the events of Spider-Man 2 , Peter Parker has become a cultural phenomenon as Spider-Man , while Mary Jane Watson continues her Broadway career . Harry Osborn still seeks vengeance for his father 's death , and an escaped Flint Marko falls into a particle accelerator and is transformed into a shape-shifting sand manipulator . An extraterrestrial symbiote crashes to Earth and bonds with Peter , influencing his behavior for the worse .