The Ozarks are in North America.
Appalachian Mountains . les Appalaches ) , often called the Appalachians , are a system of mountains in eastern North America . Arkansas ( [ ˈɑrkənsɔː ] ) is a state located in the southeastern region of the United States . Ouachita Mountains . Along with the Ozark Mountains , the Ouachita Mountains form the U.S. Interior Highlands , one of the few major mountainous regions between the Rocky Mountains and the Appalachian Mountains . Ozarks . Together , the Ozarks and Ouachita Mountains form an area known as the U.S. Interior Highlands , and are sometimes referred to collectively .