Katherine Heigl started acting.
Katherine Heigl . She made her film debut in That Night ( 1992 ) and later appeared in My Father the Hero ( 1994 ) as well as Under Siege 2 : Dark Territory ( 1995 ) . Heigl played Izzie Stevens on the ABC medical drama Grey 's Anatomy from 2005 to 2010 , a role for which she won the Primetime Emmy Award for Outstanding Supporting Actress in a Drama Series in 2007 .