The Ozarks are in North America.
Appalachian Mountains . les Appalaches ) , often called the Appalachians , are a system of mountains in eastern North America . Greater St. Louis . It includes parts of both the U.S. states of Missouri and Illinois . Missouri ( see pronunciations ) is a state in the Midwestern region of the United States , achieving statehood in 1821 . Ozarks . The Ozarks cover a significant portion of southern Missouri , extending as far northeast as the southwestern suburbs of St. Louis . The Rocky Mountains , commonly known as the Rockies , are a major mountain range in western North America .