The House of Lusignan reigned only during the Renaissance.
France . During the Renaissance , French culture flourished and a global colonial empire was established , which by the 20th century would be the second largest in the world . The House of Lusignan ( [ ˈluːzᵻnjɒn ] ) was a royal house of French origin , which ruled much of Europe and the Levant , including the kingdoms of Jerusalem , Cyprus , and Armenia , from the 12th through the 15th centuries during the Middle Ages .