Conan O'Brien hosts a late-night talk show in the United States.
Conan O'Brien . O'Brien was a writer and producer for The Simpsons for two seasons until he was commissioned by NBC to take over David Letterman 's position as host of Late Night in 1993 . Late Night with Conan O'Brien is an American late-night talk show hosted by Conan O'Brien that aired 2,725 episodes on NBC between 1993 and 2009 .