Lyme disease's most common symptom is a rash.
Lyme disease . The most common sign of infection is an expanding area of redness on the skin , known as erythema migrans , that begins at the site of a tick bite about a week after it has occurred . If untreated , symptoms may include loss of the ability to move one or both sides of the face , joint pains , severe headaches with neck stiffness , or heart palpitations , among others .