La contamination de la nutrition parentérale par l’ascorbylperoxyde perturbe le métabolisme énergétique chez le cochon d'inde nouveau-né
The light exposure of parenteral nutritive solutions generates peroxides such as H2O2 and ascorbylperoxide. This absence of photo-protection is associated with higher plasma triacylglycerol concentration (TG) in premature infants and, in animals, with oxidative stress and a H2O2 independent hepatic steatosis. We hypothesized that ascorbylperoxide is the active agent leading to high TG. The aim was to investigate the role of ascorbylperoxide on glucose and lipid metabolism in an animal model of neonatal parenteral nutrition.
Parenteral nutrition Preterm Ascorbylperoxide Glycolysis