@inproceedings{
dubourg-felonneau2023pinui,
title={Pi{NUI}: A Dataset of Protein-Protein Interactions for Machine Learning},
author={Geoffroy Dubourg-Felonneau and Eyal	Akiva and Daniel Wesego and Ranjani Varadan},
booktitle={NeurIPS 2023 Workshop on New Frontiers of AI for Drug Discovery and Development},
year={2023},
url={https://openreview.net/forum?id=N6uLT2MVV1}
}
We introduce a new novel dataset named PiNUI: Protein Interactions with Nearly Uniform Imbalance. PiNUI is a dataset of Protein-Protein Interactions (PPI) specifically designed for Machine Learning (ML) applications that offer a higher degree of representativeness of real-world PPI tasks compared to existing ML-ready PPI datasets. We achieve such by increasing the data size and quality, and minimizing the sampling bias of negative interactions. We demonstrate that models trained on PiNUI almost always outperform those trained on conventional PPI datasets when evaluated on various general PPI tasks using external test sets.
PiNUI: A Dataset of Protein-Protein Interactions for Machine Learning
Geoffroy Dubourg-Felonneau Eyal	Akiva Daniel Wesego Ranjani Varadan