The obsessive man was always washing hands, he had even done it so much once that it caused a what?
Options:
- use soap
- irritation
- cleanliness
- thinking
- wet towel
Step-by-step reasoning process below:

Irritation is caused by too much washing of hands. The obsessive man was always washing hands, he had even done it so much once that it caused him an irritation. The answer: irritation.