<story><title>World-first therapy using donor cells sends autoimmune diseases into remission</title><url>https://www.nature.com/articles/d41586-024-03209-4</url></story><parent_chain><item><author>kiba</author><text>Is there a way to speed up trials without compromising quality?</text></item><item><author>thebeardisred</author><text>In the US, my &amp;quot;back of the napkin&amp;quot; estimate tends to be 8-15 years, if it passes trials.</text></item><item><author>sosuke</author><text>For the sake of my question let’s assume this is legit and magically works for a wide range of autoimmune conditions. How many years away are we from being able to sign up for this treatment? 10 years? 20? 30?&lt;p&gt;It would be nice to dream of it happening sometime soon.</text></item></parent_chain><comment><author>throwup238</author><text>Only for orphan and ultra orphan diseases where there are so few patients that it’s not economically viable to do full clinical trials.&lt;p&gt;There is also a breakthrough therapy designation where the clinical evidence is solid enough to release the drug while they finish full trials but that’s only in exceptional cases.</text></comment>
<story><title>World-first therapy using donor cells sends autoimmune diseases into remission</title><url>https://www.nature.com/articles/d41586-024-03209-4</url></story><parent_chain><item><author>kiba</author><text>Is there a way to speed up trials without compromising quality?</text></item><item><author>thebeardisred</author><text>In the US, my &amp;quot;back of the napkin&amp;quot; estimate tends to be 8-15 years, if it passes trials.</text></item><item><author>sosuke</author><text>For the sake of my question let’s assume this is legit and magically works for a wide range of autoimmune conditions. How many years away are we from being able to sign up for this treatment? 10 years? 20? 30?&lt;p&gt;It would be nice to dream of it happening sometime soon.</text></item></parent_chain><comment><author>Retric</author><text>Not really, the process gets shortcut when the benefits of moving fast are dramatic enough.&lt;p&gt;So sure we could speed things up by killing more people undergoing medical experiments.  But the current approach of validating safety in humans then efficacy in humans is inherently serial.  Further a lot more stuff is going into the pipeline than actually ends up working.</text></comment>