<story><title>Evidence that the shingles vaccine prevents a good chunk of dementia cases</title><url>https://twitter.com/PGeldsetzer1/status/1661776663074738176</url></story><parent_chain><item><author>analog31</author><text>Does this mean the chickenpox vax will eliminate Alzheimer&amp;#x27;s? How many years til we know?</text></item><item><author>jvanderbot</author><text>Shingles (Herpes zoster) is implicated. The whole &amp;#x27;lifelong nervous system infection&amp;#x27; does seem a bit awful. I bet if we chip away at new kinds of herpes viruses, we&amp;#x27;ll find a fairly drastic reduction in Alzheimers.&lt;p&gt;&amp;quot;There is mounting evidence that herpes [simplex]
leads to Alzheimers&amp;quot;, so, HSV1&amp;#x2F;2 also.&lt;p&gt;And apparently having APOE4 genome makes it all worse. HSV1+APOE4=12x risk.&lt;p&gt;&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.bbc.com&amp;#x2F;future&amp;#x2F;article&amp;#x2F;20181022-there-is-mounting-evidence-that-herpes-leads-to-alzheimers&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.bbc.com&amp;#x2F;future&amp;#x2F;article&amp;#x2F;20181022-there-is-mountin...&lt;/a&gt;&lt;p&gt;EDIT: for clarity, the twitter thread showed that the shingles vaccine drastically reduces risk</text></item></parent_chain><comment><author>kodah</author><text>Chicken pox doesn&amp;#x27;t impact HSV1&amp;#x2F;2 which &lt;i&gt;a lot&lt;/i&gt; of people have and is also implicated in this analysis. There is, however, a doctor working on a cure and vaccine for HSV1&amp;#x2F;2 that will hopefully be available within the decade.</text></comment>
<story><title>Evidence that the shingles vaccine prevents a good chunk of dementia cases</title><url>https://twitter.com/PGeldsetzer1/status/1661776663074738176</url></story><parent_chain><item><author>analog31</author><text>Does this mean the chickenpox vax will eliminate Alzheimer&amp;#x27;s? How many years til we know?</text></item><item><author>jvanderbot</author><text>Shingles (Herpes zoster) is implicated. The whole &amp;#x27;lifelong nervous system infection&amp;#x27; does seem a bit awful. I bet if we chip away at new kinds of herpes viruses, we&amp;#x27;ll find a fairly drastic reduction in Alzheimers.&lt;p&gt;&amp;quot;There is mounting evidence that herpes [simplex]
leads to Alzheimers&amp;quot;, so, HSV1&amp;#x2F;2 also.&lt;p&gt;And apparently having APOE4 genome makes it all worse. HSV1+APOE4=12x risk.&lt;p&gt;&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.bbc.com&amp;#x2F;future&amp;#x2F;article&amp;#x2F;20181022-there-is-mounting-evidence-that-herpes-leads-to-alzheimers&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.bbc.com&amp;#x2F;future&amp;#x2F;article&amp;#x2F;20181022-there-is-mountin...&lt;/a&gt;&lt;p&gt;EDIT: for clarity, the twitter thread showed that the shingles vaccine drastically reduces risk</text></item></parent_chain><comment><author>xattt</author><text>MMR-V was first approved in 2005 in the US. Alzheimer’s-type dementia usually has onset in the mid-60s and 70s.&lt;p&gt;However, there are other dementias (i.e. vascular) that have other etiologies.</text></comment>