<story><title>Crispr-Resistant Viruses Build ‘Safe Rooms’ to Shield Genomes from Enzymes</title><url>https://www.ucsf.edu/news/2019/12/416116/crispr-resistant-viruses-build-safe-rooms-shield-genomes-dna-dicing-enzymes</url></story><parent_chain></parent_chain><comment><author>dannykwells</author><text>A beautiful study with interesting implications for the evolution of the different CRISPR systems. Congrats to the team. I&amp;#x27;m curious how this study, published in Nature, is different than this study:&lt;p&gt;&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.nature.com&amp;#x2F;articles&amp;#x2F;s41564-019-0612-5&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.nature.com&amp;#x2F;articles&amp;#x2F;s41564-019-0612-5&lt;/a&gt;&lt;p&gt;Published in Nature Microbiology. Maybe just the institution?</text></comment>
<story><title>Crispr-Resistant Viruses Build ‘Safe Rooms’ to Shield Genomes from Enzymes</title><url>https://www.ucsf.edu/news/2019/12/416116/crispr-resistant-viruses-build-safe-rooms-shield-genomes-dna-dicing-enzymes</url></story><parent_chain></parent_chain><comment><author>petjuh</author><text>I wonder if neclei were &amp;quot;invented&amp;quot; by viruses as those safe rooms. There are already theories that DNA was first invented by viruses to protect against cleaving by RNAases, and the presence of UDNA viruses suggests it. It would also explain how DNA had immediate selective advantage over RNA.</text></comment>