<story><title>Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]</title><url>https://www.medrxiv.org/content/10.1101/2021.12.23.21268276v1.full.pdf</url></story><parent_chain><item><author>simonsarris</author><text>This paper essentially argues that the risk of myocarditis in under-40 males getting 2 shots is greater (perhaps much greater) than the risk of getting it from COVID. There have been similar studies before, but none (that I saw) broken down by age and sex like this.&lt;p&gt;It reads:&lt;p&gt;&amp;gt; Despite more myocarditis events occurring in older persons, the risk following COVID-19 vaccination was largely restricted to younger males aged less than 40 years, where the risks of myocarditis following vaccination and infection were similar. However, the notable exception was that in younger males receiving a second dose of mRNA-1273 vaccine, the risk of myocarditis was higher following vaccination than infection, with an additional 101 events estimated following a second dose of mRNA-1273 vaccine compared to 7 events following a positive SARS-CoV-2 test.&lt;p&gt;This guy made a graph of their data, which makes it a little more clear:&lt;p&gt;&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;twitter.com&amp;#x2F;VPrasadMDMPH&amp;#x2F;status&amp;#x2F;1475145220618526729&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;twitter.com&amp;#x2F;VPrasadMDMPH&amp;#x2F;status&amp;#x2F;1475145220618526729&lt;/a&gt;</text></item></parent_chain><comment><author>jMyles</author><text>&amp;gt; This guy made a graph of their data, which makes it a little more clear:&lt;p&gt;As another commenter as has pointed out, the graph in question in included in the PDF version of this preprint (which you can see here: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.medrxiv.org&amp;#x2F;content&amp;#x2F;10.1101&amp;#x2F;2021.12.02.21267156v1.full.pdf+html&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.medrxiv.org&amp;#x2F;content&amp;#x2F;10.1101&amp;#x2F;2021.12.02.21267156v...&lt;/a&gt;).&lt;p&gt;I want to add: &amp;quot;this guy&amp;quot; is Vinay Prasad, a professor of oncology at UCSF and an incredibly prescient thinker through the COVID-19 pandemic, and someone with whome I&amp;#x27;ve had the joy to correspond and repeatedly be impressed by his straightforward, evidence-based, dry-witty way of thinking, writing, and speaking.&lt;p&gt;He&amp;#x27;s a significant up-and-come in medical science, without a doubt, and someone to follow if you are interested in science-based policy.&lt;p&gt;We had the pleasure of hosting an AMA with him on &amp;#x2F;r&amp;#x2F;lockdownskepticism which you may find enjoyable and educational: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.reddit.com&amp;#x2F;r&amp;#x2F;LockdownSkepticism&amp;#x2F;comments&amp;#x2F;m0ll33&amp;#x2F;hi_im_vinay_prasad_from_the_university_of&amp;#x2F;&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.reddit.com&amp;#x2F;r&amp;#x2F;LockdownSkepticism&amp;#x2F;comments&amp;#x2F;m0ll33&amp;#x2F;...&lt;/a&gt;</text></comment>
<story><title>Risk of myocarditis following sequential COVID-19 vaccinations by age and sex [pdf]</title><url>https://www.medrxiv.org/content/10.1101/2021.12.23.21268276v1.full.pdf</url></story><parent_chain><item><author>simonsarris</author><text>This paper essentially argues that the risk of myocarditis in under-40 males getting 2 shots is greater (perhaps much greater) than the risk of getting it from COVID. There have been similar studies before, but none (that I saw) broken down by age and sex like this.&lt;p&gt;It reads:&lt;p&gt;&amp;gt; Despite more myocarditis events occurring in older persons, the risk following COVID-19 vaccination was largely restricted to younger males aged less than 40 years, where the risks of myocarditis following vaccination and infection were similar. However, the notable exception was that in younger males receiving a second dose of mRNA-1273 vaccine, the risk of myocarditis was higher following vaccination than infection, with an additional 101 events estimated following a second dose of mRNA-1273 vaccine compared to 7 events following a positive SARS-CoV-2 test.&lt;p&gt;This guy made a graph of their data, which makes it a little more clear:&lt;p&gt;&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;twitter.com&amp;#x2F;VPrasadMDMPH&amp;#x2F;status&amp;#x2F;1475145220618526729&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;twitter.com&amp;#x2F;VPrasadMDMPH&amp;#x2F;status&amp;#x2F;1475145220618526729&lt;/a&gt;</text></item></parent_chain><comment><author>ozdave</author><text>Thanks for the explanation.&lt;p&gt;&amp;gt;  argues that the risk of myocarditis in under-40 males getting 2 shots is greater (perhaps much greater) than the risk of getting it from COVID&lt;p&gt;The way I read this is the risk of myocarditis is greater with vaccination, but this does not tell me about the overall risk of serious illness&amp;#x2F;death from Covid for vaxed VS unvaxed.&lt;p&gt;So - risk of myocarditis goes up - but is it still overall safer to be vaccinated for the under 40 males, or not?&lt;p&gt;Not pushing any angle or side here - just looking for clarity (as much as possible).</text></comment>