<story><title>Probiotics can support the effect of antidepressants</title><url>https://www.unibas.ch/en/News-Events/News/Uni-Research/Good-bacteria-to-tackle-depression.html</url></story><parent_chain><item><author>zackmorris</author><text>I finally beat my digestive issues and chronic fatigue (physical depression) which lasted 3+ years from 2019-2021. Without getting too far into it, here&amp;#x27;s the stuff that finally worked, weighted by immediacy on a scale of 10:&lt;p&gt;- 10: Eating a serving of Brussels sprouts, preferably daily&lt;p&gt;- 10: Taking about 3 psyllium husk capsules occasionally with FODMAP and spicy meals&lt;p&gt;- 10: Taking a digestive enzyme occasionally with FODMAP and spicy meals (Digest Basic, no affiliation)&lt;p&gt;- 10: Taking a &amp;quot;stress&amp;quot; B complex with 100% daily, instead of 1000% weekly (Nature Made, no affiliation)&lt;p&gt;- 10: Avoiding all beans, unaged dairy, whole-grain wheat and most tree nuts for a few months&lt;p&gt;- 8: Drinking at least twice as much water as I feel that I need, from one big container over the course of the day&lt;p&gt;- 8: Eating plain giant salads with dressing, preferably spinach-greens mix, several times per week&lt;p&gt;- 8: Drinking Kefir daily&lt;p&gt;- 6: Trying several different brands of probiotics occasionally in no particular order&lt;p&gt;- 6: Eating 1-4 eggs per day, preferably on post-workout days&lt;p&gt;- 6: Taking an iodine supplement initially, a few times per week until the bottle was gone&lt;p&gt;I think what kicked this all off was dabbling with keto 5 years ago which might have cost me most of my tolerance to milk, and prolonged dehydration from intense workouts and large servings of protein without proactive hydration. When I lost my gut health, I may have picked up bad bacteria or parasites from food poisoning or raw seafood. I was also under debilitating stress during the last few years at my previous job, so began every morning on an empty tank spiritually. I never listened to my body until my health failed and it made the decision to stop for me.&lt;p&gt;The biggest change has been that being tired feels ordinary and rare, with no emotional component. Instead of the crushing &amp;quot;universe is against me&amp;quot; sense of being attacked, alone and hopeless knowing there was no end of it in sight, which I endured for many years before my physical health&amp;#x27;s deterioration finally caught up.</text></item></parent_chain><comment><author>DantesKite</author><text>I can give some context for what may have happened because I went through something similar.&lt;p&gt;My two cents is the biggest factors were the keto and the stress. A low carb, high fat diet does not traditionally feature intact plant cell walls, or what we otherwise know as &amp;quot;fiber&amp;quot;. There are literally thousands of different of variations of &amp;quot;fiber&amp;quot; of which we have catalogued only a few, but these structures feed the microbiota in your gut. And they really do depend on fiber in a profound way.&lt;p&gt;Without this fiber, they tend to starve and adjust to feed on the epithelial lining of your gut. It also gives an opportunity for the pathogens in your gut to &amp;quot;takeover&amp;quot;, especially when paired with the stress since most of the &amp;quot;beneficial&amp;quot; microbes will tend to die off.&lt;p&gt;When you read stories of people who got an autoimmune problem, there&amp;#x27;s almost always a period of severe stress prior to it. My working hypothesis is this impairs the immune system which is what keeps the pathogenic bacteria in check through several mechanisms (pathogen-associated-molecular-pattern detection or PAMPs for instance).&lt;p&gt;Through much, much trial and error and a lot of scientific article research, I&amp;#x27;ve found the most consistent way to restore microbiota ratios is with Vitamin D, followed by a clinically tested probiotic like Visbiome, followed by Kefir. The Vitamin D alone at moderate to high doses will get you very far, although it doesn&amp;#x27;t necessarily restore diversity (since Vitamin D in of itself does not contain any microbes) but it helps shift the balance of microbes through a variety of biochemical functions.&lt;p&gt;Vitamin D also helps with gum disease in my experience and in a way no other supplement or product has so far. Highly recommend and you don&amp;#x27;t even have to take a high dosage to see it for yourself. You just have to be consistent.&lt;p&gt;One last thing I&amp;#x27;ll say is that for whatever reason taking the supplement seems to work better than exposing yourself to sunlight, which is unusual, but there may be something about the biochemical pathway Vitamin D takes when consumed as a supplement as opposed through the cholesterol-synthesis that happens with UVB.</text></comment>
<story><title>Probiotics can support the effect of antidepressants</title><url>https://www.unibas.ch/en/News-Events/News/Uni-Research/Good-bacteria-to-tackle-depression.html</url></story><parent_chain><item><author>zackmorris</author><text>I finally beat my digestive issues and chronic fatigue (physical depression) which lasted 3+ years from 2019-2021. Without getting too far into it, here&amp;#x27;s the stuff that finally worked, weighted by immediacy on a scale of 10:&lt;p&gt;- 10: Eating a serving of Brussels sprouts, preferably daily&lt;p&gt;- 10: Taking about 3 psyllium husk capsules occasionally with FODMAP and spicy meals&lt;p&gt;- 10: Taking a digestive enzyme occasionally with FODMAP and spicy meals (Digest Basic, no affiliation)&lt;p&gt;- 10: Taking a &amp;quot;stress&amp;quot; B complex with 100% daily, instead of 1000% weekly (Nature Made, no affiliation)&lt;p&gt;- 10: Avoiding all beans, unaged dairy, whole-grain wheat and most tree nuts for a few months&lt;p&gt;- 8: Drinking at least twice as much water as I feel that I need, from one big container over the course of the day&lt;p&gt;- 8: Eating plain giant salads with dressing, preferably spinach-greens mix, several times per week&lt;p&gt;- 8: Drinking Kefir daily&lt;p&gt;- 6: Trying several different brands of probiotics occasionally in no particular order&lt;p&gt;- 6: Eating 1-4 eggs per day, preferably on post-workout days&lt;p&gt;- 6: Taking an iodine supplement initially, a few times per week until the bottle was gone&lt;p&gt;I think what kicked this all off was dabbling with keto 5 years ago which might have cost me most of my tolerance to milk, and prolonged dehydration from intense workouts and large servings of protein without proactive hydration. When I lost my gut health, I may have picked up bad bacteria or parasites from food poisoning or raw seafood. I was also under debilitating stress during the last few years at my previous job, so began every morning on an empty tank spiritually. I never listened to my body until my health failed and it made the decision to stop for me.&lt;p&gt;The biggest change has been that being tired feels ordinary and rare, with no emotional component. Instead of the crushing &amp;quot;universe is against me&amp;quot; sense of being attacked, alone and hopeless knowing there was no end of it in sight, which I endured for many years before my physical health&amp;#x27;s deterioration finally caught up.</text></item></parent_chain><comment><author>mrharrison</author><text>I had similar issues.  I went and saw a functional medicine doctor, had a stool test and he diagnosed me with candida overgrowth.  Which may be what you had.  Here is the diet protocol for beating back candida, which is similar to the diet you put yourself on.  &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.thecandidadiet.com&amp;#x2F;&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.thecandidadiet.com&amp;#x2F;&lt;/a&gt;</text></comment>