<story><title>Rapamycin: The unlucky history of an anti-aging drug</title><url>https://bigthink.com/health/unlucky-history-rapamycin-anti-aging/</url></story><parent_chain></parent_chain><comment><author>tysam_and</author><text>Anti-aging is a hard problem, Rapamycin is most certainly not the most powerful anti-aging drug from my best understanding, it just targets 1 of 7 or 8 critical areas that are implicated in the aging formula.&lt;p&gt;If you want to start down the rabbithole (SENS talks can be trusted and are good, well-backed by science, etc etc. Have been derailed by some drama recently, but still, they&amp;#x27;ve really done a lot) then you can start by going to the rejuvenation roadmap: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.lifespan.io&amp;#x2F;road-maps&amp;#x2F;the-rejuvenation-roadmap&amp;#x2F;&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.lifespan.io&amp;#x2F;road-maps&amp;#x2F;the-rejuvenation-roadmap&amp;#x2F;&lt;/a&gt;&lt;p&gt;A little further (Aubrey de Grey, from SENS originally): &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.ted.com&amp;#x2F;talks&amp;#x2F;aubrey_de_grey_a_roadmap_to_end_aging?language=tt&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.ted.com&amp;#x2F;talks&amp;#x2F;aubrey_de_grey_a_roadmap_to_end_ag...&lt;/a&gt;&lt;p&gt;If you want to lose 4-5+ hours (minimum -- think TVTropes level of rabbithole addiction here), then here is your next free joyride. It&amp;#x27;s a fun one, I&amp;#x27;ve been pretty interested in it as it&amp;#x27;s continued to have developed. Have fun reading the saga: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.reddit.com&amp;#x2F;r&amp;#x2F;sleephackers&amp;#x2F;comments&amp;#x2F;ohfetn&amp;#x2F;turnbuckle_longecity_mitochondrial_fissionfusion&amp;#x2F;&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.reddit.com&amp;#x2F;r&amp;#x2F;sleephackers&amp;#x2F;comments&amp;#x2F;ohfetn&amp;#x2F;turnbu...&lt;/a&gt;</text></comment>
<story><title>Rapamycin: The unlucky history of an anti-aging drug</title><url>https://bigthink.com/health/unlucky-history-rapamycin-anti-aging/</url></story><parent_chain></parent_chain><comment><author>starchild_3001</author><text>Many of us know and follow rapamycin&amp;#x27;s story. There are some Drs in USA who&amp;#x27;re willing to prescribe it for longevity. I do hope some billionare will be willing to spend a few million on it to test it in clinical trials. Surely one of the most promising molecules out there, and very little sides when dosed intermittently.</text></comment>