Burlington Freight House are two separate buildings that are joined by a wood post and beam shelter. The station has twin facades. The rail side faces south and the north side faces a parking lot on River Drive. Similarly, the freight house was built with docks on the north and south sides of the building in order to facilitate the transfer of cargo.

The station is a two-story, Georgian Revival, tan brick building.  It is built on a concrete foundation. The building features a stylized Greek temple front on the north and south elevations, which emphasizes the building's entrances. The temple features four columns that are attached to the building with tapered, square shafts and stylized capitals. The columns support a Classical entablature that includes dentils, round medallions,Newcastle upon Tyne, United Kingdom), Arnold Berk (UCLA, Los Angeles, CA), and Stephen Jane (Monash University, Melbourne, Australia) for constructs and technical advice, Kathy Brundage for flow cytometry, Karen Martin and Amanda Ammer for imaging expertise, Ryan Percifield for assistance in RNA library construction, Neil Infante for bioinformatics support, Peter Mathers, Sarah McLaughlin, and Emily Ellis for animal management, Paolo Fagone for protein preparation, Carlton Bates and Kenneth Walker for kidney development techniques, and Mary Davis for Ingenuity Pathway Analysis. The work was supported by grants from the Mary Kay Foundation and the National Institute of General Medical Sciences (U54GM104942). J.D. was supported in part by the West Virginia IDeA Network for Biomedical Research Excellence (National Institutes of Health/National Institute of General Medical Sciences Grant P20GM103434). National Institutes