millennia are compiled, and can be divided into two parts: "Huang ti so ven", where simple questions and answers try to come to life truths and "Lingshu" on acupuncture. The first book, Pent-Sao, describes herbs and medicines (3000 years old), and is practically the first known pharmacopoeia in the civilization of mankind. In this pharmacopoeia, systematization of medicinal plants and other medicinal substances was performed. The earliest period of ***Indian medicine*** (about 1500 to 500 BC) is the Vedic period, as all the knowledge was contained in the sacred poems Vedas. In the oldest Ring-Vedi and somewhat younger Atharva-Vedi is reflected the religious-magical medicine: illnesses are considered devils that need to be expelled with a magical ritual. Dietetics in practical medicine were at a high level. Indians werewell aware of the effects of many herbs. Among medicines the most commonly used were medications for: vomiting, sneezing and cleansing the bowels. ***Greek and Roman culture*** has provided the basis for the development of all sciences, including pharmacy. The ancient Greek empiricism was closely related to religion. The priests of Asclepius were both doctors and pharmacists. Respect for God's doctors spread from Trike to Tesalia to all of Greece, and in 293 BC, during the plague, also to Rome. Its temples were called "Asklepieon", and there were around 185 of them. They were usually associated with a hospital and a health resort where the treatment was performed by prayers, sacrifices, religious rites, suggestions, diets, and medicines. The most famous Greek representative of pharmacy and medicine development is