commitment to promoting the growth of health research through the training of young investigators. The Division of Clinical Pharmacology is well-funded, highly collaborative, with strong research projects in adult, pediatric, and obstetric pharmacogenetics, drug metabolism, and drug interactions. The applicant's train- ing will include mentors and a faculty advisory committee consisting of NIH-funded investigators with expertise in kinetics, bioinformatics, physiologically-based computational modeling, and circulating exosome biology. By the completion of this K08 award, I will develop high-quality publications, fruitful collaborations, independent (R01) and collaborative research funding with feedback from my mentors and faculty advisors.against frailty ([@CR16]).

The aim of the present study is to assess a 3-month impact on physical function of a "real life" program for frail older adults in the community, based on the integration of primary care, geriatric medicine, and community services.

Methods {#Sec2}
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The methodology of the +AGIL Barcelona program ("Atenció primària i Geriatria Integrades amb visió Longitudinal" in Catalan) is described elsewhere ([@CR16]). Shortly, it stems from a strategic alliance between the principal public provider of primary care in Barcelona (Institut Català de la Salut, Àmbit d'Atenció Primària de Barcelona) and the major public provider of intermediate care, geriatrics and palliative care in Catalonia (Parc Sanitari Pere Virgili). The program is conducted in the primary care center of Bordeta-Magòria (Barcelona, Spain), which provides healthcare services to 32,340 citizens (20%