World, One Health' strategy and the objectives in the strategic framework, which was first released at the International Ministerial Conference on Avian and Pandemic Influenza in Sharm el-Sheikh. During the meeting, key recommendations emerged for actions that countries could take to advance the concepts of One Health.International Ministerial Conference on Avian and Pandemic Influenza in Hanoi, Vietnam, 19--21 April 2010A total of 71 countries and regional bodies, along with representatives from international organizations, development banks, and other stakeholders, attended the International Ministerial Conference on Avian and Pandemic Influenza in Hanoi, Vietnam. With the experience of the H1N1 pandemic and highly pathogenic H5N1 avian influenza, participants confirmed the need to bring greater attention to the links between human and animal health to address threats that happen when there isclose interface between animals, humans, and the ecosystem. At the conclusion of the meeting, participants unanimously adopted the Hanoi Declaration, which called for focused action at the animal--human--ecosystem interface and recommended broad implementation of One Health.The FAO, the OIE, and the WHO, April 2010Recognizing that managing and responding to EIDs is complex and requires multisectoral cooperation, the FAO, the OIE, and the WHO joined together to publish the concept in April 2010. This paper proposes a long-term strategic direction for international collaboration aimed at sharing responsibilities and coordinating global activities to address health risks that arise when humans, animals, and the ecosystem interface.CDC, 4--6 May 2010CDC in collaboration with the OIE, the FAO, and the WHO hosted a meeting in Stone Mountain, GA, titled "Operationalizing 'One Health': A