Driver of bus that hit Mass. house was new to job

AUBURN, Mass. (AP) — The man driving a regional transit bus that crashed into a house in central Massachusetts earlier this week was on his first day of service.

The Telegram & Gazette reports (http://bit.ly/1227YGh) that the driver of the bus was 27-year-old Francis Artey of Worcester (WUS'-tur).

Worcester Regional Transit Authority official John Carney says Artey went through a rigorous, eight-week training program before "driving in service" for the first time Monday. Carney says Artey was an experienced school bus driver with a stellar driving record.

Police say it appears the brakes weren't applied before the bus smashed into the house in Auburn. They say Artey may have had a medical problem, or there may have been a mechanical problemGaucher's disease: the best laid schemes of mice and men.
The creation of animal models of Gaucher's disease, the inherited deficiency of the enzyme glucocerebrosidase, has led to new clinical insights and to a new appreciation of the complexity of the glucocerebrosidase gene locus. Murine embryonic stem cells with targeted modifications in the glucocerebrosidase gene were used to generate mouse models of Gaucher's disease, the first having a null glucocerebrosidase allele. The resulting knockout mice have no glucocerebrosidase activity and die within 12 hours of birth. Ultrastructural studies of liver, spleen, brain and bone marrow demonstrate the characteristic storage material seen in Gaucher patients. In the nervous system, storage of lipid increased in a rostral-caudal distribution. Analysis of skin from the knockout mice revealed histological, ultrastructural and biochemical abnormalities.