and other measures. After the 1980s, through the general survey of endemic diseases and dynamic monitoring of endemic diseases control departments at all levels, a comprehensive investigation and study on endemic fluorosis in Ningxia was carried out. On this basis, local disease control departments try to change the situation of high incidence of endemic fluorosis in South-Central region of Ningxia through a series of comprehensive engineering projects. The local government has relocated about 1 million people of south-central region of Ningxia by ecological migration project to the plain and high platform area along Yellow River, the Yellow River water as the main drinking water source, which greatly reduced the incidence rate of endemic fluorosis. At the same time, the local government of Ningxia diverted the Yellow River waterto Tongxin County, Haiyuan County, Hongsibu District, Yuanzhou District, and other places in the south-central region of Ningxia through the water diversion project, which changed the habit of drinking shallow groundwater and Qingshui River water in these areas, and solved the drinking water problem of most of the population in the areas with a high incidence of endemic fluorosis. From 2000 to 2017, the total number of endemic villages was showing a downward trend, especially the more serious endemic fluorosis such as skeletal fluorosis and the number of people were gradually decreasing. However, due to the relatively scattered administrative villages in the south-central region of Ningxia, there are still some villages taking shallow groundwater as drinking water. The local governments need to build large and medium-sized reservoirs as