0:06Skip to 0 minutes and 6 secondsWhen my father was in his mid 50s, he started to have problems. He was finding it difficult to remember things, he was making mistakes with his work, and he was needing to be prompted with most things. And so that we knew it was something wrong. He went to the doctors, he was sent to the hospital for tests, and he was diagnosed with Alzheimer's disease, which we'd never heard of. It wasn't really long after that that one of his sisters, who was younger than my father-- she was only in her early 50s-- and she started developing the same sort of symptoms.

0:43Skip to 0 minutes and 43 secondsAnd she had a brother, and the next thing we knew wasto work on it. I think I have the original letter here. Martin Rossor picked it up, and John Hardy, and Mike Mullan. There was a team of them here. And they actually applied to get to grant, to explore the family, which they got. And in 1991, they turned up to take blood samples, and Carol coordinated across the family, to get all the family giving blood. And she was-- I mean, she's always been quite a motivated, social person.

1:58Skip to 1 minute and 58 secondsShe got the whole family: cousins, second cousins, all of the family on the paternal side, where the problem was. It wasn't maternal; it was the paternal side. She got them all involved, and they came up and took blood tests from