and normal gap junction channel functioning and calcium signaling, but it is described that Cx26 expression is altered in Cx30 null mice.  The researchers hypothesized that co-regulation of Cx26 and Cx30 is dependent on phospholipase C signaling and the NF-κB pathway.

The cochlea contains two cell types, auditory hair cells for mechanotransduction and supporting cells.  Gap junction channels are only found between cochlear supporting cells.  While gap junctions in the inner ear are critically involved in potassium recycling to the endolymph, connexin expression in the supporting cells surrounding the organ of Corti have been found to support epithelial tissue lesion repair following loss of sensory hair cells.  An experiment with Cx30 null mice found deficits in lesion closure and repair of the organ of CortiMark Coulier, the director of Coulier Creatures, and colleagues said they had to do nearly 5,000 makeups in "World War Z" during a zombie scene. "Basically you've got these guys running down the street and there's a hundred of them and you may glimpse a makeup on one of them, so you have to do the hundred, really," Coulier said.

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His eyes were black as night, his teeth jagged, his nostrils unnaturally large. It's said that when movie audiences first saw him, they fainted in fright.

Lon Chaney's 1925 portrayal of the Phantom of the Opera was spooky indeed — and an impressive testament to what the actor could do with greasepaint and a bit of