of drug released was proportional to the square root of time. The release rates of both drugs increased linearly with increasing drug concentration and polyvinyl pyrrolidone fraction in the film, but was found to be independent of film thickness. The increase in release rate may be due to leaching of hydrophilic fraction of the film former which resulted in the formation of pores. It was also observed that the release of drugs from the films followed a diffusion-controlled model at low drug concentrations. A burst effect was observed initially, however, at high drug loading levels. This may be due to rapid dissolution of the surface drug followed by the diffusion of drug through the polymer network in the film. The in vitro skin permeation profiles showed increased fluxThe present invention is directed to a core processing device and more particularly, a core processing device used for golf course maintenance and commercial lawn care.
To facilitate turf growth, aerator machines are used to relieve turf compaction and thatch build up. The machines aerate the turf by punching holes in the turf, which create sod plugs, also known as sod cores. The sod cores are generally cylindrical and comprise a layer of grass, a tightly woven layer of thatch, and a layer of roots and soil including rocks, sand, and clay. The thatch layer, which includes both living and dead matter, grows in an outwardly expanding layer above the soil, which significantly deters growth thus necessitating removal. In contrast, the soil and root layer is often composed of