[A case of duodenal perforation during mFOLFOX6 treatment for metastatic sigmoid colon cancer].
We present a case of metastatic sigmoid colon cancer causing duodenal perforation during modified FOLFOX6 chemotherapy. The patient was a 68-year-old man who underwent sigmoidectomy for an advanced sigmoid cancer in September 2007. He has been received mFOLFOX6 chemotherapy for multiple liver metastases since January 2009. In March 2010, the patient complained of abdominal pain during the 24th course of chemotherapy, and was admitted to our hospital. On admission, his vital signs were normal, and abdominal findings revealed no peritonitis signs. An abdominal CT scan showed free air and fluid collection on the first day of admission. The patient was diagnosed with gastrointestinal perforation, and underwent emergency operation for abdominal drainage. The leakage of biliary fluidscatches for 12 yards in that game.

Brown followed that up with two catches for 35 yards in a Week 4 loss at Baltimore despite being on the field for only 12 plays. Avant had two catches for 24 yards and was on the field for 41 plays.

The Panthers may have cut Avant sooner, but Brown suffered a concussion during a Week 7 loss at Green Bay and wasn't able to play in the next three games.

His touchdown against Atlanta was a signal the former Ohio State star was ready to contribute again.

Nine-year veteran receiver Jason Avant failed to create separation in his 11 games as a Panther. AP Photo/Bob Leverone

That Avant didn't have a catch in 34 plays and Brown had a big one in 16 likely sealed