where it will begin to grow multiple acres of algae in open ponds. The goal for the demonstration plant is 100 barrels a day by 2015 and by 2018 a projected 5,000 to 10,000 barrels a day.

Though several years off, full commercialization will be a game-changing payoff for America, says Warner, whose career straddles big oil and beginning green.

A chemical engineer, Warner, 53, was group vice president for BP (once known as British Petroleum), overseeing all its refineries worldwide. She was the first — and only — woman to do this for a major oil company. Warner moved from London to Del Mar just before the Macondo/BP blowout in the Gulf of Mexico. “It’s wonderful to be on the side of the angels,” she laughs.

She sat down recentlylevels and release in the medial preoptic area and medial basal hypothalamus, actions that may be mediated by activation of GPER and/or ERβ. Estradiol, as well as tamoxifen and fulvestrant, have been found to rapidly induce lordosis through activation of GPER in the arcuate nucleus of the hypothalamus of female rats.

Metabolic roles 
Female GPER knockout mice display hyperglycemia and impaired glucose tolerance, reduced body growth, and increased blood pressure. Male GPER knockout mice are observed to have increased growth, body fat, insulin resistance and glucose intolerance, dyslipidemia, increased osteoblast function (mineralization), resulting in higher bone mineral density and trabecular bone volume, and persistent growth plate activity resulting in longer bones. The GPER-selective agonist G-1 shows therapeutic efficacy in mouse models of obesity and diabetes.

Role in cancer 
Although GPER