to enter this National Historic Landmark District. Explore the former prison via the award-winning audio guide, and enjoy a sightseeing tour of the Golden Gate Bridge, the Palace of Fine Arts, and Fort Point on a cable car retrofitted with wheels, so you can see more of the city.

Sail across San Francisco Bay at twilight to admire the city skyline as it begins to light up for the night. With an experienced captain at the helm, you’ll glide past Alcatraz Island and cruise underneath the Golden Gate Bridge. Light hors d’oeuvres and two drinks are included.

Explore Napa and Sonoma's wine country in a luxury van on this full-day trip from San Francisco. With a small group limited to 14 participants and a local guide, learn about Napa andin which imipramine was infused into the anterior amygdala or caudate-putamen did not differ from saline controls. When infused into regions of the amygdala in which imipramine was active, iprindole, an "atypical" antidepressant, did not produce a behavioral response in the forced swim test. Two "false positives" in the forced swim test, atropine and amphetamine, were also not active when infused into the amygdala. These results indicate that the amygdala is a critical site of action for certain antidepressant drugs in the forced swim test, and that behavioral activation in the test induced by iprindole, amphetamine and atropine involve brain regions other than the amygdala.