Hagen

Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

A city of west-central Germany northeast of Cologne. Chartered in 1746 and famous for its textiles in the late 18th century, it became an industrial and manufacturing center after 1870. Population: 196,000.

Hagen, Walter Charles 1892-1969. American golfer who won the U.S. Open twice (1914 and 1919) and during the 1920s won the British Open four times and the PGA tournament five times.

Etymologies

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Examples

Philo Hagen is the Editor of Hooping. org and when he mentioned to me recently that the Hooper of the Week interviews were starting back up again, I told him it was time to turn the spotlight on him for a change.

Edvald Boasson Hagen (NOR) Boasson Hagen is not an out-and-out sprinter but Teambottleneck is PDH, under the repressive control of PDK1. PDK1 controls mitochondrial activities: when activated, it prevents pyruvate entry into the TCA cycle; when inactive, pyruvate is converted to acetyl-coA and may serve as a precursor for the production of the cataplerotic products citrate and isocitrate (initiating in lipid biogenesis), glutamate (generating glutamine), and malate (to produce NADPH and pyruvate through the malic enzyme reaction). NADPH, produced either in the oxidative arm of the PPP or through the malic reaction, is a necessary cosubstrate for lipid biogenesis and promotes glutathione turnover for the detoxification of ROS produced from uncoupled mitochondria. Importantly, replenishment of the TCA cycle is ensured by glutamine, taken up from the extracellular environment and recently identified as an important source of organic acids for biosynthesis