them on the run together. Ocelot returned to aid them and tended to Big Boss first, supplying him with clean clothing, a motorcycle, and a cover identity. The two shared a cigar and discussed the work ahead of them, before bidding each other farewell. Ocelot then returned and tended to Venom Snake as he came to, fleeing on horseback. The two were pursued by the Man on Fire and a young child with supernatural abilities, but managed to escape and traveled to northern Kabul, Afghanistan to rescue Miller.

Upon arrival, Ocelot emphasized that Venom Snake must revive the legend of Big Boss by performing a solo infiltration of enemy territory, although he would act as mission adviser via radio from Mother Base.[10] Following Miller's successful extraction, Ocelot continued tosupport Diamond Dogs in their mission of vengeance against Cipher, training soldiers and raising an orphaned wolf pup, training him as an attack dog that could accompany the Venom in the field.

Eventually, Ocelot and Miller received a message from Dr. "Huey" Emmerich and decided to extract him from Soviet custody for questioning, suspecting that he was responsible for MSF's downfall nine years earlier. However, Venom Snake was forced to neutralize the sniper assassin Quiet while en route, and Ocelot suggested she be brought back to base for interrogation regarding Cipher; although Miller strongly disagreed, Venom Snake ultimately followed Ocelot's advice. Afterwards, Ocelot purposely locked Quiet in a cell with a poor lock quality, expecting her to break out and reveal her motives, but she did not. Suspecting shifting