Pelotonia Junior Investigator Award, NHLBI (R01HL141941), The American Heart Association (15SDG25480000), and The Ohio State University Materials Research Seed Grant Program, funded by the Center for Emergent Materials, an NSF-MRSEC, grant DMR-1420451, the Center for Exploration of Novel Complex Materials, and the Institute for Materials Research. AA acknowledges funding from the Pelotonia Graduate Fellowship Program. MC-M acknowledges funding from an OSU Graduate Enrichment Fellowship and Discovery Scholars Fellowship.

ECs

:   endothelial cells

ECM

:   extracellular matrix

FRAP

:   fluorescent recovery after photobleaching

GAGs

:   glycosaminoglycans

HAS3

:   hyaluronan synthase 3

HA

:   hyaluronic acid

HAdase

:   hyaluronidase

IFP

:   interstitial fluid pressure

PDGFR-α

:   platelet derived growth factor receptor alpha

PDMS

:   poly(dimethylsiloxane)

PGs

:   proteoglycans

PTEN

:   phosphatase and tensin homolog

NPs

:   nanoparticles

SMO

:   smoothened

T-MOC

:four others carbon monoxided themselves in a parking garage, leaving a note that clearly linked the deaths. One week after that, a cop found two other kids trying to do the same thing in the same garage. The day after the original four suicides, but in Illinois, two other teens suicided the same way (in a garage, in fact.) Coleman writes that by checking newspapers, he counted 22 teen carbon monoxide suicides in two weeks-- 47 in a month.

But then there's the case of Barry Loukaitis, who in 1996 shot two kids and a math teach, and said he got the idea from Stephen King's Rage, Pearl Jam's Jeremy, Natural Born Killers and The Basketball Diaries. Coleman writes that "the media attention...triggered a series of similar events." So,