conclusion of her speech, attendees standing behind her could be seen leaving the event.

Warren teased that she would be making her announcement at 11 a.m. on Saturday, but she did not take stage until around an hour after the scheduled slot, during which time attendees stood outside in freezing temperatures.

The high temperature in Lawrence Saturday was 32 degrees.

Supporters walk out of @ewarren speech officially announcing her 2020 presidential bid.https://t.co/kqsJREysMn pic.twitter.com/uj9sIvvu5A — Washington Examiner (@dcexaminer) February 9, 2019

POLL: Who Would Win A 2020 Matchup: Trump Or Warren?This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Peptidylglycine ?-hydroxylating monooxygenase (PHM) is a non-coupled binuclear Cu protein, which catalyzes the stereospecific hydroxylation of the ?-carbon of the C-terminal glycine of all peptidylglycine substrates. In the catalytic mechanism, PHM binds and activates O2 for H-atom abstraction from the peptidylglycine substrate. Crystal structure of a pre-catalytic O2 intermediate is available, which demonstrates an end-on