6 a.m. ET, federal agents began driving up with the handcuffed suspects at the DEA regional office on the outskirts of Fort Lauderdale. Bosch and his attorney drove to the DEA office to surrender. Several of his associates with ties to the anti-aging/wellness business were picked up at their homes in the predawn hours and brought in for processing.

Bosch, a self-described biochemist, has been at the head of the largest performance-enhancing drug scandal in American sports history. To date, nearly 20 professional players connected to his clinic have been suspended by MLB after either having tested positive or their doping regimens having been uncovered in clinic records. The list includes some of baseball's marquee names, led by A-Rod, Ryan Braun, Nelson Cruz, Cabrera and Bartolo Colon.

The aggressive, lengthyplayers who dealt with Bosch over the years could be significantly higher.

Records reveal that Bosch also serviced athletes from other sports, entertainers and South Florida business types, often prescribing regimens of growth hormone and testosterone.

Bosch later served as the lead witness in MLB's case against Rodriguez, who appealed his suspension before dropping his fight in February. To gain Bosch's cooperation -- as well as access to his texts, emails and other evidence against A-Rod and other players -- baseball officials agreed to drop a civil lawsuit they had filed against him. MLB did that to indemnify him against civil charges while also promising to put in a good word if he was to face criminal charges, although MLB obviously isn't in position to influence a federal investigation.

Joe Tacopina,