Metabolic engineering.
Metabolic engineering is not another form of classic manipulation of intermediary metabolism; rather, it is the purposeful design of metabolic networks. The metabolic engineering approach examines biochemical reactions in their entirety, rather than individually, and is concerned with the construction of novel pathways, the thermodynamic feasibility of pathways, and the location of limiting branch-point(s) and enzymatic reaction(s) in a reaction network. The ultimate goal is the construction of strains with superior yield and productivity obtained through a convergent evolutionary process. Progress has been made toward this objective within the framework of Metabolic Control Analysis through the development of methodologies for the experimental determination of elasticities and flux control coefficients.been on a mission to convince us
that it was akin to the Great Potato Famine in Ireland,
resulting in poor bureaucrats dieing of starvation and abandoning the
country in droves on tramp steamer and leaving the local economy in ruin.

Yesterday, however, the Post admitted that perhaps the threat of the sequestration to the regions economy and had been over sold, and that things were chugging along at near normal.

In the months since the automatic federal spending cuts known as the sequester took effect, the Washington area has added 40,000 jobs. Income-tax receipts have surged in Virginia, beating expectations. Few government contractors have laid off workers.

It’s too early to be certain, but initial indications are that the damage from the sequester has been modest and slow to develop.

Labor Department statistics released