USD) at the postrelease interview.

Study design
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We examined survival, measured from study enrollment until death or a maximum of 24 months (729 days), in a random sample of HIV-infected male prisoners. The study duration was 2 years. During that time, subjects were followed until they died or were lost to follow-up, whichever occurred first. For subjects who were alive and still incarcerated at the end of the study, censoring occurred on the date they were last know alive in prison. After enrollment, participants completed a baseline assessment that consisted of surveys administered by trained researchers in the Indonesian language. During the 2-year study period, researchers attempted to contact each participant who had been released from prison to interview them by telephone or in person. When researchers discovered that aseparate functional modules: the ability to store genetic information on one hand, and the ability to function as a catalyst on the other hand. In all organisms, the informational and catalytic entities in the genome are well-separated into respectively dsDNA and ssRNA, and can therefore be seen as the mechanistic implementation of these functional modules. Their relation or interface is strictly defined and conserved throughout the Tree of Life: one part of the double-stranded DNA represents the template for the transcription of ssRNA. Thus, the separation of the informational and catalytic characteristics of RNA by a defined interface allows in principle an independent evolution of both functions as long as this interface stays intact.

Design-by-contract predicts a scenario where once established interfaces remain intact during evolution and thus enforces