Kufs' disease presenting as progressive dementia with late-onset generalized seizures: a clinicopathological and electrophysiological study.
A 32-year-old woman presented with increasing motor difficulties and memory disturbances. Neurological examination only showed mild cerebellar and extrapyramidal symptoms, whereas neuropsychological evaluation disclosed severe cognitive changes consistent with dementia. Her motor and mental status progressively deteriorated until death, which occurred 5 years after the first admission. One year before death, while she was almost bedridden, symptoms of myoclonic epilepsy first appeared, with frequent generalized seizures and generalized myoclonus, occurring especially upon sensory stimulation or passive joint movements. Pathological examination showed neuronal inclusions typical of Kufs' disease. This case, with primary progressive dementia and late-onset myoclonic epilepsy, differs from previously reported cases. Three special electrophysiological features were abnormal, "giant", evoked potentials; unusually marked photosensitivity;Tuesday, January 5, 2010, 12:20 PM.
Thomas Wikman, organist, will perform a concert of works by Pachelbel, Couperin, de Grigny, and others.
Cost: Free.
Location: Augustana Chapel at the Lutheran School of Theology, 1100 East 55th Street (55th and University), Chicago, Illinois.
For more info: Visit this site.

Friday, January 22, 2010, 7:30 PM.
The Howard Mayer Brown International Early Music Series presents Europa Galante, Fabio Biondi, conductor and violin, performing works by Telemann, Sammartini, and Vivaldi. With soloist Frank Theuns, flute.
Cost: Visit this site for details.
Location: Mandel Hall, 1131 E. 57th Street (at the corner of University Avenue), Chicago, Illinois.
For more info: call 773-702-8068; e-mail chicagopresents @ uchicago.edu; or visit this site.

Sunday, January 31, 2010, 4:00 PM.
The Early Music Series at the Byron Colby Barn presents Baroque Band in concert.
View the 2009-2010 season