Analysis and characterization of antiviral drug-resistant cytomegalovirus isolates from solid organ transplant recipients.
The development of cytomegalovirus (CMV) disease and subsequent emergence of drug-resistant strains was examined in a large group of solid organ transplant recipients; drug-resistant CMV was detected in a total of 30 transplant recipients (20 lung, 5 kidney, 4 heart, and 1 liver). Drug resistance was confirmed both phenotypically and genotypically. The sequences of drug-resistant CMV strains from the same patient differed from drug-susceptible baseline sequences only at single sites previously confirmed to confer drug resistance. At least 1 isolate from each patient had a mutation in the UL97 phosphotransferase coding sequence. Mutations in the DNA polymerase gene were found in 6 of 38 sequenced strains. Lung transplant recipients had the highest incidence of drug-resistant virus:to the world. Here you go. Now I am free.

In brief, The Luck of Ginger Coffey (Wikipedia) is the story of an ambitious but somewhat misguided Irish immigrant to Montreal in the early 1960s. Ginger Coffey is a master of well-meaning but destructive lies and misdirections, as he wages a tug-of-war between telling his wife and teenage daughter that yes, the Montreal experiment is over and we’ll soon be back in Dublin, while simultaneously chasing down his next big opportunity. The fact that he cannot afford return passage further complicates things and makes his situation even more desperate.

The film is based on a Brian Moore novel of the same title (Moore also penned the screenplay). I read the novel a couple of years after I moved to Montreal,