malaria and fever. Many new pharmaceutical dispensations have been released in Europe, mostly new editions of older books. The pharmacy laboratory has changed very much. Pharmacist had to purchase many devices of old alchemist laboratories for making chemical remedies. In the pharmaceutical laboratories of major cities, natural scientists often met. For example, in Oxford, England, naturalists, who met at the home of the pharmacist **Cross**, founded a scientific society. The Academy of Sciences in Paris has its beginning (1666) at the home of pharmacist **Geoffroy** where French naturalists gathered. Fish oil, which the people in the northern regions have for long used for medicinal purposes, was introduced in 1782 by English physicians in textbook medicine.

At the end of the 18^th^ century pharmaceutical laboratories expanded. They were not onlyused for drug production, but for scientific research and learning. They were a pharmaceutical and chemistry generator. Getting smaller quantities in pharmaceutical laboratories has become increasingly difficult for economic and technical reasons. For this reason, the authorities have allowed the pharmacist to buy such a drug also in factory labs, which have been designed to produce large quantities of chemicals. The founders of these companies were usually pharmacists. So, Pelletier soon, after discovering quinine, established a first factory in Paris for the manufacturing of this highly used antipyretic and antimalarial agent. Later, quinine was also produced in large quantities by pharmacists **Riedel** in Berlin and **Zimmer** in Frankfurt ([@ref5]).

Industrial production in the coming years has become one of the industry's leading industries and a very lucrative business. The