This is an application for an NIMH Mentored Patient-Oriented Research Career Development Award (K23). The candidate's interest is in the early identification and treatment of schizophrenia. He has previously conducted research in the phenomenology and early clinical course of schizophrenia. This career development program will allow him to pursue 1) specialized training in the methods of early detection in schizophrenia, and 2) training in the procedures necessary to conduct genotype-phenotype association analyses. Training will include individual mentoring by experts in schizophrenia research and molecular genetics at the University of Iowa, as well as training at the laboratories of external consultants who are leading the research in schizophrenia prevention. The training program will also be closely integrated with a research plan focusing on the investigation of two candidate genessame tendency. He is obscure, when he leaves out links in the chain of association, which the reader cannot easily supply... In his descriptions of children this is particularly the case, because of his firm belief in a doctrine, more poetical perhaps, than either philosophical or christian, that 'Heaven lies about us in our infancy.'"

John Taylor Coleridge continues by explaining the negative aspects of such a concept: "Though the tenderness and beauty resulting from this opinion be to us a rich overpayment for the occasional strainings and refinements of sentiment to which it has given birth, it has yet often served to make the author ridiculous in common eyes, in that it has led him to state his own fairy dreams as the true interpretation and import of