golf. Not so many patients have such a dramatic impact from a brain pacemaker, and there are multiple potential complications, but it is striking to watch a patient turn on or off the generator and go from seriously physically impaired to appearing virtually nondisabled and fully ambulatory. Bringing this image to mind reinforces a relatively newfound and extraordinary capacity for a medical device implant to take control of one's brain.

Deep brain stimulation is currently used for some other indications, including severe essential tremor, Tourette's syndrome, and severe cases of obsessive-compulsive disorder, and it is being explored for a wide range of neurologic and neuropsychiatric conditions, including bipolar disorder, post-traumatic stress, epilepsy, depression, autism, and schizophrenia. In these investigational pursuits, the brain is mapped before surgery with an fMRIIn a 2011 _Wall Street Journal_ op-ed, "America's Innovation Agency: The FDA," the FDA commissioner boasted that there had already been approval for twenty-one new medicines for the calendar year and that the approval process timing compared favorably with the European Medicines Agency. However, the attributes of efficiency and "innovation agency" are not generally perceived by the life science industry, medical community, and even the public as related to the FDA. As an integral part of Wikimedicine, the FDA needs to considerably step up its efforts to support innovation, speed up review times, foster enhanced communication and true collaboration with industry, and override previous accusations that have been leveled by members of Congress and the media of being "too cozy" with corporations, especially common in the midst of