citizens enjoy a very high per-capita income. It has a mixed economy, and it ranks above the US and most European nations on the Heritage Foundation's index of economic freedom. Canada's economy is dominated by the service industry, but it enjoys a rich natural resource sector as well. Canada is a large exporter of agricultural resources as well as gold, nickel, aluminum and lead. Canada is the largest producer of zinc and uranium, and thanks to its rich oil sands reserves, natural gas deposits and hydroelectric capacity, it is one of the few nations that are net energy exporters.

Individuals of Canadian nationality or permanent residence must provide accurate name, address, phone in Canada.
Corporations should provide exact name as registered in Canada, address, phone. Non-profit organizations should provide
their registrationdesign and coordination, and review of the manuscript.

Acknowledgements
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The authors would like to acknowledge the commitment of the Dalmatian Club of America, breeders and their veterinarians who contributed samples to the project. This work was supported by the American Kennel Club Canine Health Foundation grants Number 1870 and Number 2264. E.J.C. was supported by a National Institutes of Health (National Institute on Deafness and other Communication Disorders) Individual National Research Service Award predoctoral fellowship (1F31DC05297).
