in the development of more efficient antibiotics. The decline in antibiotic research is evident: 14 classes of antibiotics were introduced for human use between 1935 and 1968, and only five since then. The FDA had approved 29 drugs in the ‘80s (represented by 36 companies), but that number dropped to only nine after 2000. As of 2011 only seven large companies were still involved in the development of antibiotics, with Roche and Pfizer having closed their anti-bacterial R&D departments in 1999 and 2011, respectively.
Contrary to chronic conditions, such as high cholesterol, diabetes, HIV or cancer, bacterial infections are treated in a very short period of time, usually not exceeding two weeks, and therefore generating less revenue while requiring similar investment and effort. Also, when an antibiotic of superiorproviding plenty of food for thought for the business leaders of today and tomorrow" while Jeff Jarvis, author of What Would Google Do?, argues that Mainwaring "presents a truly compelling vision of how to transform that power to the benefit of society and the good of capitalism.”

We First, Inc. 
Mainwaring is the founder and CEO of We First, Inc., a Culver City-based creative consultancy that drives growth for purpose-driven driven brands. Clients include brands such as TOMS, Timberland, VF Corporation, SAP, Avery Dennison, VSP Global, Coca-Cola, Clif Bar, The Coffee Bean & Tea Leaf, Wrangler, and Reef. In 2019, Real Leaders magazine named We First one of its 100 Top Impact Companies. We First is a certified B Corporation.

Personal Life 
Mainwaring is an international speaker with engagements at