a blue summer dress was Janet’s blonde friend, Beth.“Hello, Steve,” Beth smiled swinging her pony tail as she turned to look at me. In High School, I always had a crush on Beth, probably because I saw her so often.“Judy is on the phone.”“Thanks bro,” my sister was the youngest of her friends, having turned 18 last month and she still had braces. She was a tomboy, who liked to play touch football with the boys, and ate steaks instead of salads.“Bye, Mom,” Monica waved to the SUV with one tire on our drive-way. She was wearing denim overalls over a pink t-shirt.

Beth was 18 and had been friends with Jan since junior high. Beth was no longer the skinny, flat chested girl I remember when she playedHydrogel matrices intended to release a therapeutic agent have been problematic because release is typically inadequately controlled. For example, in many cases, the majority of the agent is released from the matrix in a short burst, resulting in depletion of the agent from the hydrogel matrices. This burst is particularly undesirable when a therapeutic effect is required over an extended period of time. The short term burst is thought to be caused by the hydrophilicity of the polymeric materials driving water into the matrix, causing an increase in the osmotic pressure in the coating. As a result, the permeability of the matrix for the drug is significantly increased, resulting in the elution of the drug at a therapeutically ineffective rate.
In addition, certain polymeric materials, reagents, and/or methods of