forms of cancer.

Scientists have recognized the value of the proteins as therapeutic targets for decades, and numerous drugs, known as protein kinase inhibitors, are commonly prescribed in an attempt to slow or stop the rogue kinases that cause disease. The UGA team hopes its discovery will not only lead to new therapies but also help improve those already in existence.

"This opens a new front on the battle against many diseases, particularly cancer," says Krishnadev Oruganty, a postdoctoral research associate in biochemistry and molecular biology and lead author of a paper detailing the discovery published in the Proceedings of the National Academy of Sciences.

Developing entirely new drugs is an extraordinarily lengthy and expensive process, but this new understanding of how protein kinases switch between "on" and "off" states willAdditional Formats Available

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