Léopold, Hereditary Prince of Lorraine (26 August 1699 – 2 April 1700) died in infancy.

Élisabeth Charlotte of Lorraine (21 October 1700 – 4 May 1711) died of smallpox.

Louise Christine of Lorraine (13 November 1701 – 18 November 1701) died in infancy.

Marie Gabrièle Charlotte of Lorraine (30 December 1702 – 11 May 1711) died of smallpox.

Louis, Hereditary Prince of Lorraine (28 January 1704 – 10 May 1711) died of smallpox.

Joséphine Gabrièle of Lorraine (16 February 1705 – 25 March 1708) died in infancy.

Gabrièle Louise of Lorraine (4 March 1706 – 13 June 1710) died in infancy.

Léopold Clément, Hereditary Prince of Lorraine (25 April 1707 – 4 June 1723) died unmarried.

Francis I, Holy Roman Emperor (8 December 1708 – 18 August 1765) married Maria Theresa of Austria and had issue.

Eléonore of Lorraine (4 June 1710 – 28 July 1710) died in infancy.

Elisabeth Therese of Lorraine (15 October 1711 – 3 July 1741) married Charles Emmanuel III of Sardinia and had issue.

Charles Alexander of Lorraine (12 December 1712 – 4 July 1780) married Maria Anna of Austria and had issue.

Anne Charlotte of Lorraine (17 May 1714 - 7 November 1773) died unmarried.
Léopold, Hereditary Prince of Lorraine (26 August 1699 – 2 April 1700) died in infancy.
Élisabeth Charlotte of Lorraine (21 October 1700 – 4 May 1711) died of smallpox.
Louise Christine of Lorraine (13 November 1701 – 18 November 1701) died in infancy.
Marie Gabrièle Charlotte of Lorraine (30 December 1702 – 11 May 1711) died of smallpox.
Louis, Hereditary Prince of Lorraine (28 January 1704 – 10 May 1711) died of smallpox.
Joséphine Gabrièle of Lorraine (16 February 1705 – 25 March 1708) died in infancy.
Gabrièle Louise of Lorraine (4 March 1706 – 13 June 1710) died in infancy.
Léopold Clément, Hereditary Prince of Lorraine (25 April 1707 – 4 June 1723) died unmarried.
Francis I, Holy Roman Emperor (8 December 1708 – 18 August 1765) married Maria Theresa of Austria and had issue.
Eléonore of Lorraine (4 June 1710 – 28 July 1710) died in infancy.
Elisabeth Therese of Lorraine (15 October 1711 – 3 July 1741) married Charles Emmanuel III of Sardinia and had issue.
Charles Alexander of Lorraine (12 December 1712 – 4 July 1780) married Maria Anna of Austria and had issue.
Anne Charlotte of Lorraine (17 May 1714 - 7 November 1773) died unmarried.
Leopold, Duke of Lorraine