Several cultivars have been selected, including 'Norton', a cultivar with a substantial V. aestivalis background, is believed to be the oldest American grape cultivar in commercial production.

Inter specific-hybrids made with the species V. aestivalis, such as Norton, have shown several useful traits for commercial wine production when compared other North American native grape varieties.
These traits include: lower acidity, neutral, "vinifera-like" flavour profile, good tannin structure, and excellent disease resistance.

Unlike most other species in genus Vitis, V. aestivalis does not propagate well through dormant cuttings.
This has been a limiting factor for its use in commercial viticulture despite the species's promising oenological characteristics.
Propagation of V. aestivalis specimens must typically be made through layering or through green cuttings.
The species typically does not tolerate highly calcareous soils.

It has been claimed that a variety of V. aestivalis was cultivated by the Cherokees and used in some of their sacred rituals.
Several cultivars have been selected, including 'Norton', a cultivar with a substantial V. aestivalis background, is believed to be the oldest American grape cultivar in commercial production.
Inter specific-hybrids made with the species V. aestivalis, such as Norton, have shown several useful traits for commercial wine production when compared other North American native grape varieties. These traits include: lower acidity, neutral, "vinifera-like" flavour profile, good tannin structure, and excellent disease resistance.
Unlike most other species in genus Vitis, V. aestivalis does not propagate well through dormant cuttings. This has been a limiting factor for its use in commercial viticulture despite the species's promising oenological characteristics. Propagation of V. aestivalis specimens must typically be made through layering or through green cuttings. The species typically does not tolerate highly calcareous soils.
It has been claimed that a variety of V. aestivalis was cultivated by the Cherokees and used in some of their sacred rituals.
Vitis aestivalis