During the first half of 2010, Hilson guest featured on rapper Trina's single "Million Dollar Girl", and on T.I.'s single "Got Your Back".
In April 2010, it was made known that she had replaced Jennifer Hudson as the new face of the cosmetics and personal care products company Avon. "
Breaking Point" was released as the first single from Hilson's second studio album, No Boys Allowed, in September 2010; it only appeared on the US Hot R&B/Hip-Hop Songs Chart at number 44, and spent two weeks on the chart.
On December 2, 2010, Hilson was one of the many female artists who performed at the VH1 Divas Salute the Troops concert, where she sang "Turnin Me On", "Knock You Down", "Pretty Girl Rock", and a duet with American country music duo Sugarland on the Aretha Franklin song "Think".
No Boys Allowed was released on December 21, 2010.
Described as a "girl power album", No Boys Allowed was primarily of the R&B and pop genres.
Despite the album's title, Hilson stated "it's not about excluding men.
It's more about women understanding that there comes a time in your life when you want a man.
A real man.
A grown up.
Not a boy.
And that's not a bad thing."
Speaking of the songs on the album, she explained "I write from a female perspective, but I'm also telling men what women are really thinking and feeling about them".
In the United States, No Boys Allowed debuted at number 11 on the Billboard 200, and number seven on the Top R&B/Hip-Hop Albums chart, with first-week sales of 102,000 copies.
Although the album sold 8,000 copies more than Hilson's debut album In a Perfect World..., it failed to match that album's debut chart position of number four on the Billboard 200, due to No Boys Allowed being released during the festive season with several Christmas albums debuting inside the top-ten.
As of February 2011, the album has sold 205,500 copies in the United States.

Hilson achieved success with the album's second single, "Pretty Girl Rock", which reached number 24 on the Billboard Hot 100 and number four on the Hot R&B/Hip-Hop Songs Chart, eventually being certified platinum.
The song spent 14 weeks on the Hot 100 and four weeks on the Hot R&B/Hip-Hop Songs Chart.
It reached the top twenty in Germany and New Zealand, and top thirty in Austria and Slovakia.
Hilson promoted "Pretty Girl Rock" with live performances on televised shows, including The Tonight Show with Jay Leno, the Late Show with David Letterman and Jimmy Kimmel Live!. "
One Night Stand" featuring Chris Brown, and "Lose Control (Let Me Down)" featuring Nelly, were released as the album's third and fourth singles, respectively.
In 2011, she was featured on British rapper Chipmunk's single "In the Air", for his album Transition (2011).
In April 2011, Hilson, along with many other R&B and hip hop acts, traveled to Australia to be part of its biggest urban music festival, Supafest.
At the 2011 BET Awards, Hilson was nominated for Best Female R&B Artist and Video of the Year for "Pretty Girl Rock".
In July 2011, she was a supporting act on the second leg of Lil Wayne's I Am Still Music Tour in North America, before embarking on her first headlining European tour in October.
Hilson made her acting debut in the romantic comedy film Think Like a Man, released on April 20, 2012.
She also appeared alongside Vin Diesel in the sci-fi action film Riddick (2013), in a brief role as a prisoner allowed to escape to make room for Riddick.
During the first half of 2010, Hilson guest featured on rapper Trina's single "Million Dollar Girl", and on T.I.'s single "Got Your Back". In April 2010, it was made known that she had replaced Jennifer Hudson as the new face of the cosmetics and personal care products company Avon. "Breaking Point" was released as the first single from Hilson's second studio album, No Boys Allowed, in September 2010; it only appeared on the US Hot R&B/Hip-Hop Songs Chart at number 44, and spent two weeks on the chart. On December 2, 2010, Hilson was one of the many female artists who performed at the VH1 Divas Salute the Troops concert, where she sang "Turnin Me On", "Knock You Down", "Pretty Girl Rock", and a duet with American country music duo Sugarland on the Aretha Franklin song "Think". No Boys Allowed was released on December 21, 2010. Described as a "girl power album", No Boys Allowed was primarily of the R&B and pop genres. Despite the album's title, Hilson stated "it's not about excluding men. It's more about women understanding that there comes a time in your life when you want a man. A real man. A grown up. Not a boy. And that's not a bad thing." Speaking of the songs on the album, she explained "I write from a female perspective, but I'm also telling men what women are really thinking and feeling about them". In the United States, No Boys Allowed debuted at number 11 on the Billboard 200, and number seven on the Top R&B/Hip-Hop Albums chart, with first-week sales of 102,000 copies. Although the album sold 8,000 copies more than Hilson's debut album In a Perfect World..., it failed to match that album's debut chart position of number four on the Billboard 200, due to No Boys Allowed being released during the festive season with several Christmas albums debuting inside the top-ten. As of February 2011, the album has sold 205,500 copies in the United States.
Hilson achieved success with the album's second single, "Pretty Girl Rock", which reached number 24 on the Billboard Hot 100 and number four on the Hot R&B/Hip-Hop Songs Chart, eventually being certified platinum. The song spent 14 weeks on the Hot 100 and four weeks on the Hot R&B/Hip-Hop Songs Chart. It reached the top twenty in Germany and New Zealand, and top thirty in Austria and Slovakia. Hilson promoted "Pretty Girl Rock" with live performances on televised shows, including The Tonight Show with Jay Leno, the Late Show with David Letterman and Jimmy Kimmel Live!. "One Night Stand" featuring Chris Brown, and "Lose Control (Let Me Down)" featuring Nelly, were released as the album's third and fourth singles, respectively. In 2011, she was featured on British rapper Chipmunk's single "In the Air", for his album Transition (2011). In April 2011, Hilson, along with many other R&B and hip hop acts, traveled to Australia to be part of its biggest urban music festival, Supafest. At the 2011 BET Awards, Hilson was nominated for Best Female R&B Artist and Video of the Year for "Pretty Girl Rock". In July 2011, she was a supporting act on the second leg of Lil Wayne's I Am Still Music Tour in North America, before embarking on her first headlining European tour in October. Hilson made her acting debut in the romantic comedy film Think Like a Man, released on April 20, 2012. She also appeared alongside Vin Diesel in the sci-fi action film Riddick (2013), in a brief role as a prisoner allowed to escape to make room for Riddick.
Keri Hilson