Al-Bouti was killed while giving a religious lesson to students at the Al-Iman Mosque in the central Mazraa district of Damascus.
The bomb attack reportedly killed at least 42 people and wounded more than 84.
It marked the first time during the civil war a suicide bomber detonated explosives inside a mosque.
Al-Bouti's death is said to have removed "one of the few remaining pillars of opposition to the uprising" among the majority Sunni Muslims who have formed the base of support for the uprising.

According to Thomas Pierret – a lecturer in Contemporary Islam at the University of Edinburgh – the death of Al-Bouti means the loss of the "last credible ally among the Sunni religious elite" for the Syrian government.
 Al-Bouti was "a Muslim scholar of world standing," Pierret states.

There was no immediate claim of responsibility for the attack and both the government and the opposition condemned the attack and accused each other of perpetrating it.
Among opposition forces there was "a mixture of suspicion and shock that a notable religious figure ... would be targeted" by a suicide bomber inside a mosque.
Al-Bouti was killed while giving a religious lesson to students at the Al-Iman Mosque in the central Mazraa district of Damascus. The bomb attack reportedly killed at least 42 people and wounded more than 84. It marked the first time during the civil war a suicide bomber detonated explosives inside a mosque. Al-Bouti's death is said to have removed "one of the few remaining pillars of opposition to the uprising" among the majority Sunni Muslims who have formed the base of support for the uprising.
According to Thomas Pierret – a lecturer in Contemporary Islam at the University of Edinburgh – the death of Al-Bouti means the loss of the "last credible ally among the Sunni religious elite" for the Syrian government.  Al-Bouti was "a Muslim scholar of world standing," Pierret states.
There was no immediate claim of responsibility for the attack and both the government and the opposition condemned the attack and accused each other of perpetrating it. Among opposition forces there was "a mixture of suspicion and shock that a notable religious figure ... would be targeted" by a suicide bomber inside a mosque.
Muhammad Said Ramadan al-Bouti