On January 5, 2010, Mammoliti filed his nomination papers at City Hall to run for mayor in the 2010 City of Toronto elections.
He unveiled a platform that included building a floating casino, introducing a municipal lottery, reversing tax increases he had he previously voted for and creating a red light district for prostitution as well as an 11 pm curfew for children under the age of 14 and giving guns to by-law enforcement officers.
He also promised budget cuts and intended to target the $40 million in annual city grants to arts, cultural and community groups but was opposed to cutting salaries for elected officials.
He also called for cars to be banned from the Gardiner Expressway, converting the thoroughfare into a garden, and implementing road tolls.

During his campaign, Mammoliti and fellow mayoral candidate and councillor Rob Ford co-sponsored a motion to deny city funding to the Toronto Gay Pride Parade if it didn't ban the group Queers Against Israeli Apartheid (QuAIA) from participating.
Mammoliti also attended the 2010 Toronto Gay Pride Festival where he was shown in a YouTube video to be "stalking" the activity and presence of QuAIA with a videocamera he held in the parade.

After campaigning for six months without exceeding single digits in public opinion polls, Mammoliti announced his withdrawal from the contest on July 5, 2010 in order to run for re-election as a city councillor.

On February 4, 2013, the city's compliance audit committee voted to commence legal proceedings against Mammoliti after an audit found his 2010 election campaign exceeded the authorized spending limit by more than $12,000.
On January 5, 2010, Mammoliti filed his nomination papers at City Hall to run for mayor in the 2010 City of Toronto elections. He unveiled a platform that included building a floating casino, introducing a municipal lottery, reversing tax increases he had he previously voted for and creating a red light district for prostitution as well as an 11 pm curfew for children under the age of 14 and giving guns to by-law enforcement officers. He also promised budget cuts and intended to target the $40 million in annual city grants to arts, cultural and community groups but was opposed to cutting salaries for elected officials. He also called for cars to be banned from the Gardiner Expressway, converting the thoroughfare into a garden, and implementing road tolls.
During his campaign, Mammoliti and fellow mayoral candidate and councillor Rob Ford co-sponsored a motion to deny city funding to the Toronto Gay Pride Parade if it didn't ban the group Queers Against Israeli Apartheid (QuAIA) from participating. Mammoliti also attended the 2010 Toronto Gay Pride Festival where he was shown in a YouTube video to be "stalking" the activity and presence of QuAIA with a videocamera he held in the parade.
After campaigning for six months without exceeding single digits in public opinion polls, Mammoliti announced his withdrawal from the contest on July 5, 2010 in order to run for re-election as a city councillor.
On February 4, 2013, the city's compliance audit committee voted to commence legal proceedings against Mammoliti after an audit found his 2010 election campaign exceeded the authorized spending limit by more than $12,000.
Giorgio Mammoliti