On November 28, 2000 VFA-105 embarked on the maiden deployment of USS Harry S. Truman to the Mediterranean and Persian Gulf in support of Operation Southern Watch (OSW).
 The Gunslingers deployed in support of Operation Iraqi Freedom aboard Harry S. Truman in 2003, operating from the Mediterranean Sea.

VFA-105 became the first East Coast squadron to transition to the F/A-18E Super Hornet in July 2006.
In March 2007, VFA-105 became the first operational Navy strike fighter squadron to be commanded by a female when CDR Sara Joyner took command.
On November 28, 2000 VFA-105 embarked on the maiden deployment of USS Harry S. Truman to the Mediterranean and Persian Gulf in support of Operation Southern Watch (OSW).  The Gunslingers deployed in support of Operation Iraqi Freedom aboard Harry S. Truman in 2003, operating from the Mediterranean Sea.
VFA-105 became the first East Coast squadron to transition to the F/A-18E Super Hornet in July 2006. In March 2007, VFA-105 became the first operational Navy strike fighter squadron to be commanded by a female when CDR Sara Joyner took command.
VFA-105