In 2013, Citigroup had shortlisted the tower as one of three potential locations for its headquarters for when its lease on 399 Park Avenue expired in 2017.
The company eventually chose nearby 388 Greenwich Street, however: a building that it already had under lease.

Silverstein has faced considerable difficulty in persuading tenants to lease floorspace in Two World Trade Center.
Most commonly, businesses ultimately decide against doing so because of the costs of moving in, but others prefer their current locations in Midtown Manhattan despite the leases sometimes being more costly, since Midtown Manhattan offers easier access to the Upper East Side, North Jersey, Long Island, Westchester, and Connecticut.
Silverstein has tried to appeal to the Downtown's proximity to nearby Brooklyn, the residence of many technology and media companies' employees.
At present, prospective companies either are too large to be housed adequately in 2 World Trade Center (such as Facebook or Google), or conclude it would save money to remain where they are (such as News Corp and Fox Corporation).

Bloomberg Business reported on June 2, 2015, that News Corp and 21st Century Fox, both owned by Rupert Murdoch, had signed a non-binding agreement with the Port Authority of New York and New Jersey to create a joint headquarters at Two World Trade Center.
Silverstein said, "A decision by 21st Century Fox and News Corp. to move to the new World Trade Center would cap a seismic shift that has taken place in Lower Manhattan over the past decade.
This isn't your grandfather's Wall Street."
The change of lead architects, from Norman Foster to Bjarke Ingels, was dependent on the Murdoch companies' relocations to the site; a redesign was deemed necessary given the different requirements for TV studios as opposed to financial companies, the assumed major tenants for the Foster design.
Ingels's design would be kept at the same height as Foster's, but it was unclear how the redesign would conflict with the below-grade work already completed, which conformed to the original building design.
On January 15, 2016, it was reported that the two companies had decided against moving into 2 World Trade Center, instead keeping their current headquarters on the Avenue of the Americas.
They had concluded that "given the scale of investment in a relocation of this size, that  [sic] our resources would be better directed elsewhere."

In September 2017, Deutsche Bank was considering relocating their U.S. headquarters to 2 WTC, signing on as anchor tenant once their lease expires at their current location along nearby 60 Wall Street.
In two separate instances in September 2017, Silverstein said that the tower had a planned completion date of 2022.
However, in May 2018, it was announced the bank was instead relocating to Time Warner Center at Columbus Circle.
In 2013, Citigroup had shortlisted the tower as one of three potential locations for its headquarters for when its lease on 399 Park Avenue expired in 2017. The company eventually chose nearby 388 Greenwich Street, however: a building that it already had under lease.
Silverstein has faced considerable difficulty in persuading tenants to lease floorspace in Two World Trade Center. Most commonly, businesses ultimately decide against doing so because of the costs of moving in, but others prefer their current locations in Midtown Manhattan despite the leases sometimes being more costly, since Midtown Manhattan offers easier access to the Upper East Side, North Jersey, Long Island, Westchester, and Connecticut. Silverstein has tried to appeal to the Downtown's proximity to nearby Brooklyn, the residence of many technology and media companies' employees. At present, prospective companies either are too large to be housed adequately in 2 World Trade Center (such as Facebook or Google), or conclude it would save money to remain where they are (such as News Corp and Fox Corporation).
Bloomberg Business reported on June 2, 2015, that News Corp and 21st Century Fox, both owned by Rupert Murdoch, had signed a non-binding agreement with the Port Authority of New York and New Jersey to create a joint headquarters at Two World Trade Center. Silverstein said, "A decision by 21st Century Fox and News Corp. to move to the new World Trade Center would cap a seismic shift that has taken place in Lower Manhattan over the past decade. This isn't your grandfather's Wall Street." The change of lead architects, from Norman Foster to Bjarke Ingels, was dependent on the Murdoch companies' relocations to the site; a redesign was deemed necessary given the different requirements for TV studios as opposed to financial companies, the assumed major tenants for the Foster design. Ingels's design would be kept at the same height as Foster's, but it was unclear how the redesign would conflict with the below-grade work already completed, which conformed to the original building design. On January 15, 2016, it was reported that the two companies had decided against moving into 2 World Trade Center, instead keeping their current headquarters on the Avenue of the Americas. They had concluded that "given the scale of investment in a relocation of this size, that  [sic] our resources would be better directed elsewhere."
In September 2017, Deutsche Bank was considering relocating their U.S. headquarters to 2 WTC, signing on as anchor tenant once their lease expires at their current location along nearby 60 Wall Street. In two separate instances in September 2017, Silverstein said that the tower had a planned completion date of 2022. However, in May 2018, it was announced the bank was instead relocating to Time Warner Center at Columbus Circle.
2 World Trade Center