MD 151 begins at an intersection with 7th Street within the former Bethlehem Steel complex.
Sparrows Point Boulevard continues south to a gate south of F Street.
MD 151 heads northeast as a four-lane divided highway.
The state highway leaves the steel complex by crossing over the Patapsco & Back Rivers Railroad and Wharf Road, also identified as MD 151B, with which MD 151 has a modified trumpet interchange.
At Sparrows Point Road, MD 151's name changes to North Point Boulevard and the highway curves north to bypass Edgemere.
The state highway intersects MD 158 (Bethlehem Boulevard); to the east MD 158 provides access to North Point Road, which heads south through Edgemere toward North Point State Park and Fort Howard.
Just north of MD 158, MD 151 has a partial interchange with I-695 (Baltimore Beltway), which includes a ramp from MD 151 to northbound I-695 and a loop ramp from southbound I-695 to MD 151.
The movements to and from the Francis Scott Key Bridge to the south are made via MD 158 to the west.

MD 151 passes under a rail line owned by Norfolk Southern Railway and intersects Wise Avenue before passing through the North Point Village neighborhood of Dundalk, where the highway is paralleled by North Point Road on the east.
At Cove Road, a connector between MD 151 and I-695, North Point Road switches to the west side of MD 151.
The area north of North Point Village, where the Patapsco River Neck narrows to a width of 1 mile (1.6 km) between the Back River and Bear Creek, was the site of the Battle of North Point, a September 12, 1814 engagement that was part of the encompassing Battle of Baltimore in the War of 1812.
At Bread and Cheese Creek, northbound MD 151 crosses to the east side of I-695, which runs in the median of the state highway.
Northbound MD 151 and northbound I-695 and the southbound directions of each highway are connected to each other by ramps.
Northbound MD 151 crosses over I-695 and has a U-turn ramp before the highway's partial cloverleaf interchange with the ramps between I-695 and the northern end of MD 157 (Merritt Boulevard).
There is no access from northbound MD 151 to MD 157 or between MD 151 and the ramps to I-695.
The state highway continues northwest along the southern edge of the Eastpoint Mall ahead of its cloverleaf interchange with MD 150 (Eastern Avenue), then enters an industrial area where the highway has a grade crossing of the Canton Railroad.

MD 151 enters the city of Baltimore just west of its intersection with Rolling Mill Road and Kane Street.
The state highway passes under I-95, a Norfolk Southern Railway railyard, and Amtrak's Northeast Corridor.
At North Point Road, MD 151's name changes to Erdman Avenue and the highway veers west to pass under CSX's Philadelphia Subdivision.
The state highway veers northwest at its crossing of I-895 (Harbor Tunnel Thruway) just before the highway's cloverleaf interchange with US 40 (Pulaski Highway), which also includes a ramp from southbound MD 151 to southbound I-895.
Connections between eastbound US 40 and northbound MD 151 are made via Mapleton Avenue just east of I-895.
MD 151 continues northwest concurrent with US 40 Truck as a six-lane boulevard between the Armistead Gardens neighborhood to the east and industrial facilities on the west.
The state highway passes by Archbishop Curley High School and through the Belair-Edison neighborhood before reaching its northern terminus at US 1 (Belair Road), onto which US 40 Truck turns west.
Erdman Avenue continues northwest as a two-lane undivided street along the eastern edge of Clifton Park to MD 147 (Harford Road).

MD 151 is a part of the National Highway System as an intermodal connector from I-695 in Dundalk to I-95 in Baltimore and as a principal arterial from I-95 to its northern terminus at US 1 in Baltimore.
MD 151 begins at an intersection with 7th Street within the former Bethlehem Steel complex. Sparrows Point Boulevard continues south to a gate south of F Street. MD 151 heads northeast as a four-lane divided highway. The state highway leaves the steel complex by crossing over the Patapsco & Back Rivers Railroad and Wharf Road, also identified as MD 151B, with which MD 151 has a modified trumpet interchange. At Sparrows Point Road, MD 151's name changes to North Point Boulevard and the highway curves north to bypass Edgemere. The state highway intersects MD 158 (Bethlehem Boulevard); to the east MD 158 provides access to North Point Road, which heads south through Edgemere toward North Point State Park and Fort Howard. Just north of MD 158, MD 151 has a partial interchange with I-695 (Baltimore Beltway), which includes a ramp from MD 151 to northbound I-695 and a loop ramp from southbound I-695 to MD 151. The movements to and from the Francis Scott Key Bridge to the south are made via MD 158 to the west.
MD 151 passes under a rail line owned by Norfolk Southern Railway and intersects Wise Avenue before passing through the North Point Village neighborhood of Dundalk, where the highway is paralleled by North Point Road on the east. At Cove Road, a connector between MD 151 and I-695, North Point Road switches to the west side of MD 151. The area north of North Point Village, where the Patapsco River Neck narrows to a width of 1 mile (1.6 km) between the Back River and Bear Creek, was the site of the Battle of North Point, a September 12, 1814 engagement that was part of the encompassing Battle of Baltimore in the War of 1812. At Bread and Cheese Creek, northbound MD 151 crosses to the east side of I-695, which runs in the median of the state highway. Northbound MD 151 and northbound I-695 and the southbound directions of each highway are connected to each other by ramps. Northbound MD 151 crosses over I-695 and has a U-turn ramp before the highway's partial cloverleaf interchange with the ramps between I-695 and the northern end of MD 157 (Merritt Boulevard). There is no access from northbound MD 151 to MD 157 or between MD 151 and the ramps to I-695. The state highway continues northwest along the southern edge of the Eastpoint Mall ahead of its cloverleaf interchange with MD 150 (Eastern Avenue), then enters an industrial area where the highway has a grade crossing of the Canton Railroad.
MD 151 enters the city of Baltimore just west of its intersection with Rolling Mill Road and Kane Street. The state highway passes under I-95, a Norfolk Southern Railway railyard, and Amtrak's Northeast Corridor. At North Point Road, MD 151's name changes to Erdman Avenue and the highway veers west to pass under CSX's Philadelphia Subdivision. The state highway veers northwest at its crossing of I-895 (Harbor Tunnel Thruway) just before the highway's cloverleaf interchange with US 40 (Pulaski Highway), which also includes a ramp from southbound MD 151 to southbound I-895. Connections between eastbound US 40 and northbound MD 151 are made via Mapleton Avenue just east of I-895. MD 151 continues northwest concurrent with US 40 Truck as a six-lane boulevard between the Armistead Gardens neighborhood to the east and industrial facilities on the west. The state highway passes by Archbishop Curley High School and through the Belair-Edison neighborhood before reaching its northern terminus at US 1 (Belair Road), onto which US 40 Truck turns west. Erdman Avenue continues northwest as a two-lane undivided street along the eastern edge of Clifton Park to MD 147 (Harford Road).
MD 151 is a part of the National Highway System as an intermodal connector from I-695 in Dundalk to I-95 in Baltimore and as a principal arterial from I-95 to its northern terminus at US 1 in Baltimore.
Maryland Route 151