The squadron was organized at Forbes Air Force Base, Kansas in July 1960 as the 548th Strategic Missile Squadron, a Strategic Air Command (SAC) SM-65E Atlas intercontinental ballistic missile launch squadron.
 Nearly 6 months later, on 24 January 1961, the first Atlas missile arrived at Forbes.
By October, all nine sites had their Atlas E missiles.
On 16 October 1961, Air Force Ballistic Missile Activation Chief, Maj.
Gen. Gerrity turned over operational control of the sites to SAC.

The squadron operated nine missile sites:
548–1, 2.5 mi N of Rock Creek, KS     39°16′47″N 095°31′50″W
548–2, 1.9 mi SW of Worden, KS     38°46′03″N 095°22′05″W
548–3, 4.8 mi WNW of Waverly, KS     38°25′50″N 095°40′42″W
548–4, 4.8 mi SSW of Burlingame, KS     38°41′41″N 095°52′48″W
548–5, 3.9 mi NW of Bushong, KS     38°41′11″N 096°18′08″W
548–6, 6.1 mi W of Dover, KS     38°58′36″N 096°02′56″W
548–7, 1.8 mi NW of Wamego, KS     39°13′22″N 096°19′32″W
548–8, 2.5 mi E of Delia, KS     39°14′42″N 095°55′10″W
548–9, 4.2 mi N of Holton, KS     39°31′33″N 095°44′25″W
During the Cuban Missile Crisis, on 20 October 1962, SAC directed that the squadron's Atlas E missiles that were not on alert for modifications be placed on alert status "as covertly as possible."
 Training was suspended and missiles being used for operational training were to be placed on alert as soon as liquid oxygen became available.
From 3 November the number of alert missiles was reduced until on 29 November the number was the same as before the crisis.
 As tensions eased, on 15 November normal training resumed.
    
In August 1964, the squadron's parent 40th Strategic Aerospace Wing became nonoperational and the squadron was reassigned to the 55th Strategic Reconnaissance Wing.
 This assignment was short-lived, as on 19 November 1964, the Department of Defense announced that all Atlas E and F and Titan I missiles were being removed from the inventory.
  The first squadron missiles were taken off alert on 4 January 1965.
 Removal of missiles from alert and shipment to Norton Air Force Base, California at a rate of two per week began in January 1965 and was complete by 12 February 1965.
 The squadron was inactivated on 25 March 1965 and its missile sites turned over to the base civil engineer for management until transferred to the General Services Administration for disposal.
The squadron was organized at Forbes Air Force Base, Kansas in July 1960 as the 548th Strategic Missile Squadron, a Strategic Air Command (SAC) SM-65E Atlas intercontinental ballistic missile launch squadron.  Nearly 6 months later, on 24 January 1961, the first Atlas missile arrived at Forbes. By October, all nine sites had their Atlas E missiles. On 16 October 1961, Air Force Ballistic Missile Activation Chief, Maj. Gen. Gerrity turned over operational control of the sites to SAC.
The squadron operated nine missile sites:
548–1, 2.5 mi N of Rock Creek, KS     39°16′47″N 095°31′50″W
548–2, 1.9 mi SW of Worden, KS     38°46′03″N 095°22′05″W
548–3, 4.8 mi WNW of Waverly, KS     38°25′50″N 095°40′42″W
548–4, 4.8 mi SSW of Burlingame, KS     38°41′41″N 095°52′48″W
548–5, 3.9 mi NW of Bushong, KS     38°41′11″N 096°18′08″W
548–6, 6.1 mi W of Dover, KS     38°58′36″N 096°02′56″W
548–7, 1.8 mi NW of Wamego, KS     39°13′22″N 096°19′32″W
548–8, 2.5 mi E of Delia, KS     39°14′42″N 095°55′10″W
548–9, 4.2 mi N of Holton, KS     39°31′33″N 095°44′25″W
During the Cuban Missile Crisis, on 20 October 1962, SAC directed that the squadron's Atlas E missiles that were not on alert for modifications be placed on alert status "as covertly as possible."  Training was suspended and missiles being used for operational training were to be placed on alert as soon as liquid oxygen became available. From 3 November the number of alert missiles was reduced until on 29 November the number was the same as before the crisis.  As tensions eased, on 15 November normal training resumed.     
In August 1964, the squadron's parent 40th Strategic Aerospace Wing became nonoperational and the squadron was reassigned to the 55th Strategic Reconnaissance Wing.  This assignment was short-lived, as on 19 November 1964, the Department of Defense announced that all Atlas E and F and Titan I missiles were being removed from the inventory.   The first squadron missiles were taken off alert on 4 January 1965.  Removal of missiles from alert and shipment to Norton Air Force Base, California at a rate of two per week began in January 1965 and was complete by 12 February 1965.  The squadron was inactivated on 25 March 1965 and its missile sites turned over to the base civil engineer for management until transferred to the General Services Administration for disposal.
548th Strategic Missile Squadron