Karl Ernst von Baer was born into the Baltic German noble Baer family (et) in the Piep Manor (et), Jerwen County, Governorate of Estonia (in present-day Lääne-Viru County, Estonia), as a knight by birthright.
His family was of Westphalian origin and originated in Osnabrück.
He spent his early childhood at Lasila manor, Estonia.
Many of his ancestors had come from Westphalia.
He was educated at the Knight and Cathedral School in Reval (Tallinn) and the Imperial University of Dorpat (Tartu), each of which he found lacking in quality of education.
In 1812, during his tenure at the university, he was sent to Riga to aid the city after Napoleon's armies had laid siege to it.
As he attempted to help the sick and wounded, he realized that his education at Dorpat had been inadequate, and upon his graduation, he notified his father that he would need to go abroad to "finish" his education.
 In his autobiography, his discontent with his education at Dorpat inspired him to write a lengthy appraisal of education in general, a summary that dominated the content of the book.
 After leaving Tartu, he continued his education in Berlin, Vienna, and Würzburg, where Ignaz Döllinger introduced him to the new field of embryology.

In 1817, he became a professor at Königsberg University (Kaliningrad) and full professor of zoology in 1821, and of anatomy in 1826.
In 1829, he taught briefly in St Petersburg, but returned to Königsberg.
In 1834, Baer moved back to St Petersburg and joined the St Petersburg Academy of Sciences, first in zoology (1834–46) and then in comparative anatomy and physiology (1846–62).
His interests while there were anatomy, ichthyology, ethnography, anthropology, and geography.
While embryology had kept his attention in Königsberg, then in Russia von Baer engaged in a great deal of field research, including the exploration of the island Novaya Zemlya.
The last years of his life (1867–76) were spent in Dorpat, where he became a major critic of Charles Darwin.
Karl Ernst von Baer was born into the Baltic German noble Baer family (et) in the Piep Manor (et), Jerwen County, Governorate of Estonia (in present-day Lääne-Viru County, Estonia), as a knight by birthright. His family was of Westphalian origin and originated in Osnabrück. He spent his early childhood at Lasila manor, Estonia. Many of his ancestors had come from Westphalia. He was educated at the Knight and Cathedral School in Reval (Tallinn) and the Imperial University of Dorpat (Tartu), each of which he found lacking in quality of education. In 1812, during his tenure at the university, he was sent to Riga to aid the city after Napoleon's armies had laid siege to it. As he attempted to help the sick and wounded, he realized that his education at Dorpat had been inadequate, and upon his graduation, he notified his father that he would need to go abroad to "finish" his education.  In his autobiography, his discontent with his education at Dorpat inspired him to write a lengthy appraisal of education in general, a summary that dominated the content of the book.  After leaving Tartu, he continued his education in Berlin, Vienna, and Würzburg, where Ignaz Döllinger introduced him to the new field of embryology.
In 1817, he became a professor at Königsberg University (Kaliningrad) and full professor of zoology in 1821, and of anatomy in 1826. In 1829, he taught briefly in St Petersburg, but returned to Königsberg. In 1834, Baer moved back to St Petersburg and joined the St Petersburg Academy of Sciences, first in zoology (1834–46) and then in comparative anatomy and physiology (1846–62). His interests while there were anatomy, ichthyology, ethnography, anthropology, and geography. While embryology had kept his attention in Königsberg, then in Russia von Baer engaged in a great deal of field research, including the exploration of the island Novaya Zemlya. The last years of his life (1867–76) were spent in Dorpat, where he became a major critic of Charles Darwin.
Karl Ernst von Baer