Pescia was selected by Boca Juniors at 12 years old, starting at the 7th.
division.
He debuted in the senior squad on August 30, 1942, when Boca was beat by Chacarita Juniors by 2-1.
The next season, Pescia was part of one of the most remembered midfield lines in the history of the club, along with Carlos Sosa and Ernesto Lazzatti between 1943 and 1947 when Boca Juniros won the 1943 and 1944 domestic leagues, apart from one Copa Ibarguren, one Copa de Competencia Británica and two Copa Escobar-Gerona.

In 1954 Boca Juniors won a local tournament after 10 years without titles, with Pescia as captain and former teammate Ernesto Lazzatti as coach.
Sosa played a total of 15 seasons for Boca Juniors, being its last official match the 4-1 victory over Huracán, on December 2, 1956.

Despite its professional retirement, Pescia played some friendly matches with the team.
In 1957 he and other players representing Boca Juniors played a match v. Paraguayan team Olimpia in Asunción.

Pescia played 12 games for the Argentina national team, being called up for the first time in 1945 to play the Copa América, although he did not play any match.
The next year Pescia was called up again for the 1946 tournament, debuting v. Bolivia in a smashing victory by 7-1.

In the 1947 edition Pescia played 6 games for the national side and Argentina won its third consecutive title.
Pescia's last games with Argentina was in 1954 when the squad defeated Portugal by 3-1.

After retiring from football, Pescia was candidate to president of Boca Juniors, being defeated by Alberto J. Armando.

Pescia died in Avellaneda at 67 years old, on November 11, 1989.
The club honored him naming "Tribuna Natalio Pescia" to one of La Bombonera grandstands.
Pescia was selected by Boca Juniors at 12 years old, starting at the 7th. division. He debuted in the senior squad on August 30, 1942, when Boca was beat by Chacarita Juniors by 2-1. The next season, Pescia was part of one of the most remembered midfield lines in the history of the club, along with Carlos Sosa and Ernesto Lazzatti between 1943 and 1947 when Boca Juniros won the 1943 and 1944 domestic leagues, apart from one Copa Ibarguren, one Copa de Competencia Británica and two Copa Escobar-Gerona.
In 1954 Boca Juniors won a local tournament after 10 years without titles, with Pescia as captain and former teammate Ernesto Lazzatti as coach. Sosa played a total of 15 seasons for Boca Juniors, being its last official match the 4-1 victory over Huracán, on December 2, 1956.
Despite its professional retirement, Pescia played some friendly matches with the team. In 1957 he and other players representing Boca Juniors played a match v. Paraguayan team Olimpia in Asunción.
Pescia played 12 games for the Argentina national team, being called up for the first time in 1945 to play the Copa América, although he did not play any match. The next year Pescia was called up again for the 1946 tournament, debuting v. Bolivia in a smashing victory by 7-1.
In the 1947 edition Pescia played 6 games for the national side and Argentina won its third consecutive title. Pescia's last games with Argentina was in 1954 when the squad defeated Portugal by 3-1.
After retiring from football, Pescia was candidate to president of Boca Juniors, being defeated by Alberto J. Armando.
Pescia died in Avellaneda at 67 years old, on November 11, 1989. The club honored him naming "Tribuna Natalio Pescia" to one of La Bombonera grandstands.
Natalio Pescia