In his third season, Neres scored his first official European goal against Standard Liège in the second leg of the third qualifying round of the Champions League.
In that year, Neres wasn't guaranteed a starting spot up until February.
Because of this, there were rumours that Neres wanted to leave.
In January, Guangzhou Evergrande made a £36.9 million bid on Neres, but Ajax ultimately refused, because they wanted to keep the team together to win prizes that year and make it far in the UEFA Champions League.
In the second leg in the round of 16 of the UEFA Champions League, in a memorable game against Real Madrid, Neres scored the second goal to give Ajax the lead on aggregate, and the Dutch side eventually won a by a margin of 5–3, thus knocking the three-time defending European champions out of the competition.

On 31 March 2019, Neres scored the winning goal and picked up a penalty in the championship clash against PSV, to win 3–1.
He also scored an important equaliser against Juventus at home to secure hopes for Ajax's semi-final qualification in the first leg at home.

Neres won his first Eredivisie title as Ajax finished three points ahead of rivals PSV.
Neres also won his first KNVB Cup when Ajax won 4–0 against Willem II in the final.
In his third season, Neres scored his first official European goal against Standard Liège in the second leg of the third qualifying round of the Champions League. In that year, Neres wasn't guaranteed a starting spot up until February. Because of this, there were rumours that Neres wanted to leave. In January, Guangzhou Evergrande made a £36.9 million bid on Neres, but Ajax ultimately refused, because they wanted to keep the team together to win prizes that year and make it far in the UEFA Champions League. In the second leg in the round of 16 of the UEFA Champions League, in a memorable game against Real Madrid, Neres scored the second goal to give Ajax the lead on aggregate, and the Dutch side eventually won a by a margin of 5–3, thus knocking the three-time defending European champions out of the competition.
On 31 March 2019, Neres scored the winning goal and picked up a penalty in the championship clash against PSV, to win 3–1. He also scored an important equaliser against Juventus at home to secure hopes for Ajax's semi-final qualification in the first leg at home.
Neres won his first Eredivisie title as Ajax finished three points ahead of rivals PSV. Neres also won his first KNVB Cup when Ajax won 4–0 against Willem II in the final.
David Neres