Schwartzman reached the third round at the 2017 French Open, where he faced Novak Djokovic.
He had a 2–1 set lead, but eventually Djokovic won in five sets.

In the 2017 Canadian Open the 25-year-old saved four match points to pull off a remarkable 4-6, 7–6(7), 7–5 upset of No.
3 seed Dominic Thiem (No.
7 in the world), his first-ever win over a top-10 player.
 As of mid-August 2017, he was leading the ATP tour in winning percentage in return games at 36 per cent (192/532), with Nadal in second place and Djokovic in fourth place.

On September 1, he defeated world No.
7, and 5th seed, Marin Cilic in the third round at the 2017 US Open to equal the biggest win of his career.
 On September 3, he beat world No.
20, and 16th seed, Lucas Pouille in the fourth round to reach his first career major quarterfinal.
At 5' 7" (170 cm), Schwartzman was the shortest Grand Slam quarterfinalist since Jaime Yzaga (5' 7" at the 1994 US Open).
Schwartzman said: "It’s not just for the big guys here."

Schwartzman's 2017 season proved to be the best of his career to that point.
He finished the year ranked world No.
25, in addition to making his first major quarterfinal; he also made two quarterfinals at the Masters 1000 level.
 He won 39 singles matches and earned $1,536,000 over the course of the season, easily besting his previous records of 17 match wins and $441,000 in the 2016 season.
In 2017 he led all ATP players in percentage of second serve return points won (56.1%) and percentage of return games won (34.8%), while coming in third behind Andy Murray and Rafael Nadal in percentage of first serve return points won (34.3%).
 Finally, he scored his first win over a top-10 player, and then just two weeks later he racked up a second top-10 win.
Schwartzman reached the third round at the 2017 French Open, where he faced Novak Djokovic. He had a 2–1 set lead, but eventually Djokovic won in five sets.
In the 2017 Canadian Open the 25-year-old saved four match points to pull off a remarkable 4-6, 7–6(7), 7–5 upset of No. 3 seed Dominic Thiem (No. 7 in the world), his first-ever win over a top-10 player.  As of mid-August 2017, he was leading the ATP tour in winning percentage in return games at 36 per cent (192/532), with Nadal in second place and Djokovic in fourth place.
On September 1, he defeated world No. 7, and 5th seed, Marin Cilic in the third round at the 2017 US Open to equal the biggest win of his career.  On September 3, he beat world No. 20, and 16th seed, Lucas Pouille in the fourth round to reach his first career major quarterfinal. At 5' 7" (170 cm), Schwartzman was the shortest Grand Slam quarterfinalist since Jaime Yzaga (5' 7" at the 1994 US Open). Schwartzman said: "It’s not just for the big guys here."
Schwartzman's 2017 season proved to be the best of his career to that point. He finished the year ranked world No. 25, in addition to making his first major quarterfinal; he also made two quarterfinals at the Masters 1000 level.  He won 39 singles matches and earned $1,536,000 over the course of the season, easily besting his previous records of 17 match wins and $441,000 in the 2016 season. In 2017 he led all ATP players in percentage of second serve return points won (56.1%) and percentage of return games won (34.8%), while coming in third behind Andy Murray and Rafael Nadal in percentage of first serve return points won (34.3%).  Finally, he scored his first win over a top-10 player, and then just two weeks later he racked up a second top-10 win.
Diego Schwartzman