The pressurized section carried 525 kg (1,157 lb) of cargo to the ISS, which included food, water, clothing, cargo bags, computer hardware, the NanoRacks Module 9 (student experiments and scientific gear) and other miscellaneous cargo.
No unpressurized cargo was delivered on this mission.

An unannounced addition to the cargo manifest, made public after the launch, was a small canister, affixed to the second stage's top, containing the 1-gram ash remains of over 300 people including Project Mercury Astronaut Gordon Cooper, and James Doohan, the actor who played Scotty on the television show Star Trek in the 1960s.
The remains were flown semi-secretly by Celestis, a company that has flown burial canisters in the past on SpaceX's Falcon 1 launch vehicle.
The second stage and the burial canister remained in the initial orbit Dragon C2+ was inserted to, and burned up in the Earth's atmosphere a month later.

On its return to Earth, Dragon brought back 665 kg (1,466 lb) worth of pressurized cargo back to Earth; the cargo included experiment samples, experiment hardware, ISS' systems hardware and Extravehicular Mobility Unit hardware.
One of the experiments returned by Dragon was the Shear History Extensional Rheology Experiment (SHERE) administered by NASA's Glenn Research Center.
SHERE investigated rotational stress effects on polymer fluids.
Items from SHERE included a toolbox, fluid modules, stowage trays, cables and a keyboard, and science data recordings.
Another experiment returning with Dragon was the Multi-user Droplet Combustion Apparatus (MDCA), and the Combustion Integrated Rack-Fluids and Combustion Facility (CIR).
The return flight was planned to carry 660 kg (1,460 lb)
Another experiment returning at the end of this mission was the Material Science Research Rack (MSRR), which investigated microgravity experiments on aluminum-alloy rods.
Returning from MSRR were cartridges from thermal and vacuum investigations done on metal rods in the SETA-2 and the MSL-CETSOL and MICAST studies.

Originally, SpaceX also intended to launch two secondary payload satellites from the Dragon sometime in the first 72 hours after launch; however, on 28 December 2011, SpaceX and Orbcomm announced a revised schedule that dropped the satellite deployment from the Dragon C2+ flight plan.
The pressurized section carried 525 kg (1,157 lb) of cargo to the ISS, which included food, water, clothing, cargo bags, computer hardware, the NanoRacks Module 9 (student experiments and scientific gear) and other miscellaneous cargo. No unpressurized cargo was delivered on this mission.
An unannounced addition to the cargo manifest, made public after the launch, was a small canister, affixed to the second stage's top, containing the 1-gram ash remains of over 300 people including Project Mercury Astronaut Gordon Cooper, and James Doohan, the actor who played Scotty on the television show Star Trek in the 1960s. The remains were flown semi-secretly by Celestis, a company that has flown burial canisters in the past on SpaceX's Falcon 1 launch vehicle. The second stage and the burial canister remained in the initial orbit Dragon C2+ was inserted to, and burned up in the Earth's atmosphere a month later.
On its return to Earth, Dragon brought back 665 kg (1,466 lb) worth of pressurized cargo back to Earth; the cargo included experiment samples, experiment hardware, ISS' systems hardware and Extravehicular Mobility Unit hardware. One of the experiments returned by Dragon was the Shear History Extensional Rheology Experiment (SHERE) administered by NASA's Glenn Research Center. SHERE investigated rotational stress effects on polymer fluids. Items from SHERE included a toolbox, fluid modules, stowage trays, cables and a keyboard, and science data recordings. Another experiment returning with Dragon was the Multi-user Droplet Combustion Apparatus (MDCA), and the Combustion Integrated Rack-Fluids and Combustion Facility (CIR). The return flight was planned to carry 660 kg (1,460 lb)
Another experiment returning at the end of this mission was the Material Science Research Rack (MSRR), which investigated microgravity experiments on aluminum-alloy rods. Returning from MSRR were cartridges from thermal and vacuum investigations done on metal rods in the SETA-2 and the MSL-CETSOL and MICAST studies.
Originally, SpaceX also intended to launch two secondary payload satellites from the Dragon sometime in the first 72 hours after launch; however, on 28 December 2011, SpaceX and Orbcomm announced a revised schedule that dropped the satellite deployment from the Dragon C2+ flight plan.
SpaceX COTS Demo Flight 2