C. colocynthis, a perennial plant, can propagate both by generative and vegetative means.
However, seed germination is poor due to the extreme xeric conditions, so vegetative propagation is more common and successful in nature.
In the Indian arid zone, growth takes place between January and October, but the most favorable period for the vegetative growth is during summer, which coincides with the rainy season.
Growth declines as soon as the rains and the temperature decrease and almost stops during the cold and dry months of December and January.
Colocynth prefers sandy soils and is a good example of good water management which may be useful also on research to better understand how desert plants react to water stress.
To enhance production, an organic fertilizer can be applied.

Colocynth is also commonly cultivated together with cassava (intercropping) in Nigeria.

Cultivated colocynth suffers of climatic stress and diseases such as cucumber mosaic virus, melon mosaic virus, Fusarium wilt, etc.
as any other crop.
To improve it, a relatively new protocol for regeneration has been developed with the aim of incorporating disease and stress resistance to increase yield potential and security avoiding interspecific hybridization barriers.
C. colocynthis, a perennial plant, can propagate both by generative and vegetative means. However, seed germination is poor due to the extreme xeric conditions, so vegetative propagation is more common and successful in nature. In the Indian arid zone, growth takes place between January and October, but the most favorable period for the vegetative growth is during summer, which coincides with the rainy season. Growth declines as soon as the rains and the temperature decrease and almost stops during the cold and dry months of December and January. Colocynth prefers sandy soils and is a good example of good water management which may be useful also on research to better understand how desert plants react to water stress. To enhance production, an organic fertilizer can be applied.
Colocynth is also commonly cultivated together with cassava (intercropping) in Nigeria.
Cultivated colocynth suffers of climatic stress and diseases such as cucumber mosaic virus, melon mosaic virus, Fusarium wilt, etc. as any other crop. To improve it, a relatively new protocol for regeneration has been developed with the aim of incorporating disease and stress resistance to increase yield potential and security avoiding interspecific hybridization barriers.
Citrullus colocynthis