Armenian art makes up a large part of the collection, beginning with ancient and Medieval art: Urartu frescoes and copies of Garni Temple’s mosaics and Medieval wall-paintings and miniatures, including a 7th-century fresco of "Christ Enthroned" from St. Stephanos Church (Lmbatavank), a10th-century fresco fragment of "The Last Judgment" from St. Poghos-Petros (Tatev), and a 13th-century fresco depicting the Nativity from St. Astvatsatskin (Akhtala),
The museum has an extensive collection of Armenian Apostolic Church-related paintings ranging from the 17th-19th centuries, as well as, silver book-covers of manuscripts, crosses, and 18th-century altar curtains from across Asia.

The collection of historic Armenian art is the largest in the world.
There are particularly strong collections of work by Hakob Hovnatanyan, Hovhannes Aivazovsky, Gevorg Bashinjaghian, Panos Terlemezian, Vardges Sureniants, Vartan Mahokian, Martiros Saryan, Hakob Kojoyan, Hakob Gyurjian, Edgar Chahine, Grigor Khanjyan, Minas Avetisyan, and many more.

There is a particular strength in the field of art by diasporan Armenians, and it includes works by Zakar Zakarian (Paris), Edgar Chahine (Paris), Hovsep Pushman (New York), Jean Carzou (Paris), Jean Jansem (Paris), Gerardo Oragyan (Rome), and Paul Guiragossian (Beirut).

Russian art is also extensively present in the NPGA's collection.
These include religious icons and images from the 16th and 17th centuries and works of well-known Russian artists from the 18th–20th-century, including F. Rokotov, I. Argunov, F. Shubin, Ilya Repin, Valentin Serov, Ilya Mashkov, Sergey Konenkov, Kuzma Petrov-Vodkin, Vassily Kandinsky, Natalia Goncharova, Marc Chagall, and others.

NPGA has also incorporated many examples of "foreign art" (predominantly Western) into their collection, many of which were originally part of the 'Armenian Cultural Center' (the former Lazarian Seminary, Moscow), which was nationalized during the Soviet period and moved to Yerevan.

The ancient collections include examples of ancient art from Egypt (New Kingdom, Greco-Roman, Coptic), Greece (Corinth, Attica), Rome, and Iran.
The Decorative Arts department has ceramic and porcelain collections of Chinese, Iranian, Italian, Japan, German, Austrian, Danish, and an extensive collection from the 18th–19th-century Tsarist Imperial Porcelain Factory in Russia.
There are also a small collection of bronze items from 18th-century China (Qing dynasty) and 16th–17th-century Western European wooden furniture.

There are a number of European Old Master works in their holdings, including works by well-known artists from Italy, Holland, Belgium and French art movements, including significant works by Donatello, Tintoretto, Antonio Canova, Joos de Momper, Caspar Netscher, Matthias Stomer, Jan Van Goyen, P. Claesz, E. M. Falconet, Carle Vanloo, J. B. Greuze, Joseph Vernet, Robert Hubert, Théodore Rousseau, Adolphe Monticelli.

In 2008, a pavilion was opened specifically for Hakob Gurjian’s works.

The NPGA building also houses the restoration and conservation studios affiliated with the museum.
The complex also has a moderately sized library and archive, a small cafeteria, a souvenir and book store, and a hall used for film screenings and lectures.

The NPGA also lends to international exhibitions with works from her collection, helping to organizize exhibitions of Armenian art in different countries to see that Armenia's works are appreciated by citizens around the world.
Armenian art makes up a large part of the collection, beginning with ancient and Medieval art: Urartu frescoes and copies of Garni Temple’s mosaics and Medieval wall-paintings and miniatures, including a 7th-century fresco of "Christ Enthroned" from St. Stephanos Church (Lmbatavank), a10th-century fresco fragment of "The Last Judgment" from St. Poghos-Petros (Tatev), and a 13th-century fresco depicting the Nativity from St. Astvatsatskin (Akhtala),
The museum has an extensive collection of Armenian Apostolic Church-related paintings ranging from the 17th-19th centuries, as well as, silver book-covers of manuscripts, crosses, and 18th-century altar curtains from across Asia.
The collection of historic Armenian art is the largest in the world. There are particularly strong collections of work by Hakob Hovnatanyan, Hovhannes Aivazovsky, Gevorg Bashinjaghian, Panos Terlemezian, Vardges Sureniants, Vartan Mahokian, Martiros Saryan, Hakob Kojoyan, Hakob Gyurjian, Edgar Chahine, Grigor Khanjyan, Minas Avetisyan, and many more.
There is a particular strength in the field of art by diasporan Armenians, and it includes works by Zakar Zakarian (Paris), Edgar Chahine (Paris), Hovsep Pushman (New York), Jean Carzou (Paris), Jean Jansem (Paris), Gerardo Oragyan (Rome), and Paul Guiragossian (Beirut).
Russian art is also extensively present in the NPGA's collection. These include religious icons and images from the 16th and 17th centuries and works of well-known Russian artists from the 18th–20th-century, including F. Rokotov, I. Argunov, F. Shubin, Ilya Repin, Valentin Serov, Ilya Mashkov, Sergey Konenkov, Kuzma Petrov-Vodkin, Vassily Kandinsky, Natalia Goncharova, Marc Chagall, and others.
NPGA has also incorporated many examples of "foreign art" (predominantly Western) into their collection, many of which were originally part of the 'Armenian Cultural Center' (the former Lazarian Seminary, Moscow), which was nationalized during the Soviet period and moved to Yerevan.
The ancient collections include examples of ancient art from Egypt (New Kingdom, Greco-Roman, Coptic), Greece (Corinth, Attica), Rome, and Iran. The Decorative Arts department has ceramic and porcelain collections of Chinese, Iranian, Italian, Japan, German, Austrian, Danish, and an extensive collection from the 18th–19th-century Tsarist Imperial Porcelain Factory in Russia. There are also a small collection of bronze items from 18th-century China (Qing dynasty) and 16th–17th-century Western European wooden furniture.
There are a number of European Old Master works in their holdings, including works by well-known artists from Italy, Holland, Belgium and French art movements, including significant works by Donatello, Tintoretto, Antonio Canova, Joos de Momper, Caspar Netscher, Matthias Stomer, Jan Van Goyen, P. Claesz, E. M. Falconet, Carle Vanloo, J. B. Greuze, Joseph Vernet, Robert Hubert, Théodore Rousseau, Adolphe Monticelli.
In 2008, a pavilion was opened specifically for Hakob Gurjian’s works.
The NPGA building also houses the restoration and conservation studios affiliated with the museum. The complex also has a moderately sized library and archive, a small cafeteria, a souvenir and book store, and a hall used for film screenings and lectures.
The NPGA also lends to international exhibitions with works from her collection, helping to organizize exhibitions of Armenian art in different countries to see that Armenia's works are appreciated by citizens around the world.
National Gallery of Armenia