MPP+ is produced in vivo from the precursor MPTP.
The process involves two successive oxidations of the molecule by monoamine oxidase B to form the final MPP+ product.
This metabolic process occurs predominantly in astrocytes in the brain.
MPP+ is produced in vivo from the precursor MPTP. The process involves two successive oxidations of the molecule by monoamine oxidase B to form the final MPP+ product. This metabolic process occurs predominantly in astrocytes in the brain.
MPP+