Samuel J. Kirkwood was born in 1813 in Harford County, Maryland.
 At age 17, he began teaching school and had as one of his pupils his cousin Daniel Kirkwood, who later achieved prominence as a mathematician and astronomer.
 Samuel spent part of his youth in Washington, D.C., then joined his father in moving to Ohio in 1835.
There he became a well-known anti-slavery Republican.
 He was elected to several state offices and worked closely with Thomas Bartley, the future governor of Ohio, in the 1840s.

In 1855 Kirkwood moved to Iowa, living northwest of Iowa City, and became involved with the Clark family, also from Ohio, in a milling venture, and then with the Clark and Lucas families in land speculation.
Kirkwood married Jane Clark, the sister of Phoebe Ann Clark, and thus became the brother-in-law of Edward Lucas, son of Iowa's first Territorial Governor Robert Lucas and his second wife Friendly Ashley (Sumner) Lucas.

Although Kirkwood intended to leave politics behind him in Iowa, he took an interest in the newly founded Republican Party.
Summoned from his mill at Coralville and still coated in flour dust, Kirkwood gave a rousing speech at the founding meeting of the Iowa Republican Party in February 1856.
Many people credited Kirkwood’s speech and subsequent work with the success of the Republican Party in Iowa; that year he was elected to the Iowa Senate serving from 1856 to 1859.
Samuel J. Kirkwood was born in 1813 in Harford County, Maryland.  At age 17, he began teaching school and had as one of his pupils his cousin Daniel Kirkwood, who later achieved prominence as a mathematician and astronomer.  Samuel spent part of his youth in Washington, D.C., then joined his father in moving to Ohio in 1835. There he became a well-known anti-slavery Republican.  He was elected to several state offices and worked closely with Thomas Bartley, the future governor of Ohio, in the 1840s.
In 1855 Kirkwood moved to Iowa, living northwest of Iowa City, and became involved with the Clark family, also from Ohio, in a milling venture, and then with the Clark and Lucas families in land speculation. Kirkwood married Jane Clark, the sister of Phoebe Ann Clark, and thus became the brother-in-law of Edward Lucas, son of Iowa's first Territorial Governor Robert Lucas and his second wife Friendly Ashley (Sumner) Lucas.
Although Kirkwood intended to leave politics behind him in Iowa, he took an interest in the newly founded Republican Party. Summoned from his mill at Coralville and still coated in flour dust, Kirkwood gave a rousing speech at the founding meeting of the Iowa Republican Party in February 1856. Many people credited Kirkwood’s speech and subsequent work with the success of the Republican Party in Iowa; that year he was elected to the Iowa Senate serving from 1856 to 1859.
Samuel J. Kirkwood