Borghese was the eldest son of Paolo, 9th Prince of Sulmona (1845–1920) and his wife Ilona, Countess Apponyi de Nagy-Appony.
He was twice married, firstly to Anna Maria de Ferrari (23 March 1874 – 25 November 1924), daughter of Gaetano, duca di Ferrari by his wife Maria Annenkov, on 23 May 1895, and they had two daughters.
 His second marriage to Teodora Martini on 8 August 1926 produced no issue.
 He was succeeded in the title Prince of Sulmona by his brother Livio Borghese, 11th Prince of Sulmona (1874–1939), second son of the 9th Prince.
Borghese was the eldest son of Paolo, 9th Prince of Sulmona (1845–1920) and his wife Ilona, Countess Apponyi de Nagy-Appony. He was twice married, firstly to Anna Maria de Ferrari (23 March 1874 – 25 November 1924), daughter of Gaetano, duca di Ferrari by his wife Maria Annenkov, on 23 May 1895, and they had two daughters.  His second marriage to Teodora Martini on 8 August 1926 produced no issue.  He was succeeded in the title Prince of Sulmona by his brother Livio Borghese, 11th Prince of Sulmona (1874–1939), second son of the 9th Prince.
Scipione Borghese, 10th Prince of Sulmona