In June 1450, two years after the Ottomans had captured Svetigrad, they laid siege to Krujë with an army numbering approximately 100,000 men and led again by Sultan Murad II himself and his son, Mehmed II.
Following a scorched earth strategy (thus denying the Ottomans the use of necessary local resources), Skanderbeg left a protective garrison of 1,500 men under one of his most trusted lieutenants, Vrana Konti, while, with the remainder of the army, which included many Slavs, Germans, Frenchmen and Italians, he harassed the Ottoman camps around Krujë by continuously attacking Sultan Murad II's supply caravans.
The garrison repelled three major direct assaults on the city walls by the Ottomans, causing great losses to the besieging forces.
Ottoman attempts at finding and cutting the water sources failed, as did a sapped tunnel, which collapsed suddenly.
An offer of 300,000 aspra (Ottoman silver coins) and a promise of a high rank as an officer in the Ottoman army made to Vrana Konti, were both rejected by him.

During the First Siege of Krujë, the Venetian merchants from Scutari sold food to the Ottoman army and those of Durazzo supplied Skanderbeg's army.
An angry attack by Skanderbeg on the Venetian caravans raised tension between him and the Republic, but the case was resolved with the help of the bailo of Durazzo who stopped the Venetian merchants from any longer furnishing the Ottomans.
Venetians' help to the Ottomans notwithstanding, by September 1450, the Ottoman camp was in disarray, as the castle was still not taken, the morale had sunk, and disease was running rampant.
Murad II acknowledged that he could not capture the castle of Krujë by force of arms before the winter, and in October 1450, he lifted the siege and made his way to Edirne.
The Ottomans suffered 20,000 casualties during the siege, and many more died as Murad escaped Albania.
A few months later, on 3 February 1451, Murad died in Edirne and was succeeded by his son Mehmed II (r. 1451–1481).

After the siege, Skanderbeg was at the end of his resources.
He lost all of his possessions except Krujë.
The other nobles from the region of Albania allied with Murad II as he came to save them from the oppression.
Even after the sultan's withdrawal, they rejected Skanderbeg's efforts to enforce his authority over their domains.
Skanderbeg then traveled to Ragusa, urging for assistance, and the Ragusans informed Pope Nicholas V. Through financial assistance, Skanderbeg managed to hold Krujë and regain much of his territory.
Skanderbeg's success brought praise from all over Europe and ambassadors were sent to him from Rome, Naples, Hungary, and Burgundy.
In June 1450, two years after the Ottomans had captured Svetigrad, they laid siege to Krujë with an army numbering approximately 100,000 men and led again by Sultan Murad II himself and his son, Mehmed II. Following a scorched earth strategy (thus denying the Ottomans the use of necessary local resources), Skanderbeg left a protective garrison of 1,500 men under one of his most trusted lieutenants, Vrana Konti, while, with the remainder of the army, which included many Slavs, Germans, Frenchmen and Italians, he harassed the Ottoman camps around Krujë by continuously attacking Sultan Murad II's supply caravans. The garrison repelled three major direct assaults on the city walls by the Ottomans, causing great losses to the besieging forces. Ottoman attempts at finding and cutting the water sources failed, as did a sapped tunnel, which collapsed suddenly. An offer of 300,000 aspra (Ottoman silver coins) and a promise of a high rank as an officer in the Ottoman army made to Vrana Konti, were both rejected by him.
During the First Siege of Krujë, the Venetian merchants from Scutari sold food to the Ottoman army and those of Durazzo supplied Skanderbeg's army. An angry attack by Skanderbeg on the Venetian caravans raised tension between him and the Republic, but the case was resolved with the help of the bailo of Durazzo who stopped the Venetian merchants from any longer furnishing the Ottomans. Venetians' help to the Ottomans notwithstanding, by September 1450, the Ottoman camp was in disarray, as the castle was still not taken, the morale had sunk, and disease was running rampant. Murad II acknowledged that he could not capture the castle of Krujë by force of arms before the winter, and in October 1450, he lifted the siege and made his way to Edirne. The Ottomans suffered 20,000 casualties during the siege, and many more died as Murad escaped Albania. A few months later, on 3 February 1451, Murad died in Edirne and was succeeded by his son Mehmed II (r. 1451–1481).
After the siege, Skanderbeg was at the end of his resources. He lost all of his possessions except Krujë. The other nobles from the region of Albania allied with Murad II as he came to save them from the oppression. Even after the sultan's withdrawal, they rejected Skanderbeg's efforts to enforce his authority over their domains. Skanderbeg then traveled to Ragusa, urging for assistance, and the Ragusans informed Pope Nicholas V. Through financial assistance, Skanderbeg managed to hold Krujë and regain much of his territory. Skanderbeg's success brought praise from all over Europe and ambassadors were sent to him from Rome, Naples, Hungary, and Burgundy.
Skanderbeg