Saccular aneurysms are almost always the result of hereditary weakness in blood vessels and typically occur within the arteries of the Circle of Willis, in order of frequency affecting the following arteries:
Anterior communicating artery
Posterior communicating artery
Middle cerebral artery
Internal carotid artery
Tip of basilar artery
Saccular aneurysms tend to have a lack of tunica media and elastic lamina around its dilated location (congenital), with wall of sac made up of thickened hyalinized intima and adventitia.
In addition, some parts of the brain vasculature are inherently weak—particularly areas along the Circle of Willis, where small communicating vessels link the main cerebral vessels.
These areas are particularly susceptible to saccular aneurysms.
Approximately 25% of patients have multiple aneurysms, predominantly when there is familial pattern.
Saccular aneurysms are almost always the result of hereditary weakness in blood vessels and typically occur within the arteries of the Circle of Willis, in order of frequency affecting the following arteries:
Anterior communicating artery
Posterior communicating artery
Middle cerebral artery
Internal carotid artery
Tip of basilar artery
Saccular aneurysms tend to have a lack of tunica media and elastic lamina around its dilated location (congenital), with wall of sac made up of thickened hyalinized intima and adventitia. In addition, some parts of the brain vasculature are inherently weak—particularly areas along the Circle of Willis, where small communicating vessels link the main cerebral vessels. These areas are particularly susceptible to saccular aneurysms. Approximately 25% of patients have multiple aneurysms, predominantly when there is familial pattern.
Intracranial aneurysm