On September 10, 2009, Mike Comrie signed a one-year contract worth $1.125 million with the team he began his NHL career with, returning to the Edmonton Oilers after six years, for their upcoming 2009–10 NHL season.
Comrie chose to wear No.
 91 (his overall draft selection number), as his familiar jersey No.
 89 (which he wore during his first go-round with the team), was taken by Sam Gagner.

Comrie made his return to Edmonton a night to remember, in a 4–0 pre-season win over the Florida Panthers, on September 18, 2009.
Comrie assisted on all four of the goals scored and registered a fight, squaring off with the Panthers' Eric Himelfarb, to which Comrie received a standing ovation from the Rexall Place crowd, who promptly chanted his name as he took his place inside the penalty box.

On November 17, Comrie was placed on the NHL long term injury reserve list with mononucleosis and was expected to be out until late January.
He had 5 goals and 8 points, in 16 games.
Comrie would make his return to the Oilers line-up on February 1, 2010, recording an assist in a 4–2 victory over the Carolina Hurricanes.
He finished out the rest of the season tallying 13 goals and 21 points, in 43 games.

Mike Comrie became an unrestricted free agent on July 1, 2010, with the Oilers opting not to re-sign him for the 2010–11 season.
On September 10, 2009, Mike Comrie signed a one-year contract worth $1.125 million with the team he began his NHL career with, returning to the Edmonton Oilers after six years, for their upcoming 2009–10 NHL season. Comrie chose to wear No. 91 (his overall draft selection number), as his familiar jersey No. 89 (which he wore during his first go-round with the team), was taken by Sam Gagner.
Comrie made his return to Edmonton a night to remember, in a 4–0 pre-season win over the Florida Panthers, on September 18, 2009. Comrie assisted on all four of the goals scored and registered a fight, squaring off with the Panthers' Eric Himelfarb, to which Comrie received a standing ovation from the Rexall Place crowd, who promptly chanted his name as he took his place inside the penalty box.
On November 17, Comrie was placed on the NHL long term injury reserve list with mononucleosis and was expected to be out until late January. He had 5 goals and 8 points, in 16 games. Comrie would make his return to the Oilers line-up on February 1, 2010, recording an assist in a 4–2 victory over the Carolina Hurricanes. He finished out the rest of the season tallying 13 goals and 21 points, in 43 games.
Mike Comrie became an unrestricted free agent on July 1, 2010, with the Oilers opting not to re-sign him for the 2010–11 season.
Mike Comrie