Following the departure of Paul Pogba to Manchester United in the summer of 2016, Dybala was offered the number 10 jersey by Juventus, although he turned it down, preferring to keep the number 21 jersey that he had worn during his previous season.
Following manager Massimiliano Allegri's switch to a 4–2–3–1 formation, the 2016–17 season saw Dybala operate in a deeper playmaking role behind the club's new signing Gonzalo Higuaín, which saw a decrease in his goalscoring output as he took on increasing defensive and creative duties.
After struggling to score at the beginning of the season, Dybala scored his first goal of the 2016–17 campaign on 27 September, in a 4–0 away win over Dinamo Zagreb in the Champions League.
He scored his first Serie A goal of the season that weekend, on 2 October, in a 3–0 away win over Empoli.

On 11 April, Dybala scored two goals in Juventus's first-leg Champions League quarter-final fixture against Barcelona, helping the club to a 3–0 home victory.
On 13 April 2017, Dybala renewed his contract with Juventus until 2022.
On 3 June, Dybala started in the 2017 Champions League Final, but Juventus were defeated 4–1 by defending champions Real Madrid, missing out on the treble.
Following the departure of Paul Pogba to Manchester United in the summer of 2016, Dybala was offered the number 10 jersey by Juventus, although he turned it down, preferring to keep the number 21 jersey that he had worn during his previous season. Following manager Massimiliano Allegri's switch to a 4–2–3–1 formation, the 2016–17 season saw Dybala operate in a deeper playmaking role behind the club's new signing Gonzalo Higuaín, which saw a decrease in his goalscoring output as he took on increasing defensive and creative duties. After struggling to score at the beginning of the season, Dybala scored his first goal of the 2016–17 campaign on 27 September, in a 4–0 away win over Dinamo Zagreb in the Champions League. He scored his first Serie A goal of the season that weekend, on 2 October, in a 3–0 away win over Empoli.
On 11 April, Dybala scored two goals in Juventus's first-leg Champions League quarter-final fixture against Barcelona, helping the club to a 3–0 home victory. On 13 April 2017, Dybala renewed his contract with Juventus until 2022. On 3 June, Dybala started in the 2017 Champions League Final, but Juventus were defeated 4–1 by defending champions Real Madrid, missing out on the treble.
Paulo Dybala