UDP-N-acetylenolpyruvylglucosamine Reductase (MurB) is an enzyme that catalyzes the NADPH-dependent reduction of enolpyruvyl-UDP-N-acetylglucosamine (substrate) to the corresponding D-lactyl compound UDP-N-acetylmuramic acid (product).
MurB is a monomer and contains one FAD molecule.
Before the substrate can be converted to product, NADPH must first reduce FAD.
Once NADP⁺ dissociates, the substrate can bind and the reduced flavin can reduce the product.
UDP-N-acetylenolpyruvylglucosamine Reductase (MurB) is an enzyme that catalyzes the NADPH-dependent reduction of enolpyruvyl-UDP-N-acetylglucosamine (substrate) to the corresponding D-lactyl compound UDP-N-acetylmuramic acid (product). MurB is a monomer and contains one FAD molecule. Before the substrate can be converted to product, NADPH must first reduce FAD. Once NADP⁺ dissociates, the substrate can bind and the reduced flavin can reduce the product.
Flavin adenine dinucleotide