Kane was drafted 19th overall in the 2006 WHL Bantam Draft by the Vancouver Giants.
He received his first WHL call-up for a game against the Seattle Thunderbirds on December 13, 2006, due to other Giants players international commitments in the World Junior Championships.
Kane scored his first WHL goal, a game-tying marker, on March 25, 2007, the last game of the regular season.
He also suited up for five WHL post-season games, being originally called up for the playoffs after Giants forward Tim Kraus was suspended for game three of the opening round.
He later appeared in two Memorial Cup games, tallying an assist, as part of the Giants' 2007 Memorial Cup championship.

Set to begin his rookie campaign with the Giants the following season, Kane experienced a minor setback, as he was forced to miss the start of training camp with a case of mononucleosis.
He nevertheless recovered and joined the Giants full-time to tally 24 goals – third in team scoring – and 41 points in his first WHL season.
 Finishing tenth in rookie scoring, he was nominated for the Jim Piggott Memorial Trophy as WHL rookie of the year, which was awarded to Brayden Schenn of the Brandon Wheat Kings.

Kane emerged with an impressive start to the 2008–09 season, registering at least a point in each of his first 22 games.
After recording his first WHL hat-trick on October 10, 2008, against the Kelowna Rockets, he was named WHL Player of the Week on October 12, succeeding linemate Casey Pierro-Zabotel, who had been chosen the previous week.
Kane earned a spot as an injury replacement at the 2009 World Junior Championships with Team Canada.
 Upon returning with a gold medal, Kane was named player of the week for the second time in the season on January 12, 2009, after scoring six points in two games immediately following the World Juniors.
Later that month, he participated in the 2009 CHL Top Prospects Game as captain for Team Cherry.

Kane finished his second WHL season with 48 goals and 96 points, fourth in League scoring.
He surpassed Adam Courchaine's team record of 43 goals in a single season, set in 2002–03.
Second in team scoring to Pierro-Zabotel's 115 points, the linemates finished one-two in all-time Giants' single-season scoring as Pierro-Zabotel and Kane both surpassed Gilbert Brulé's previous 87-point mark.
Kane received WHL West First Team All-Star honours along with teammates Pierro-Zabotel and Jonathon Blum.
In the subsequent 2009 playoffs, after the Giants swept the Prince George Cougars in the first round, Kane scored a double-overtime game-winner to force a seventh game in the second round against the Spokane Chiefs.
After eliminating the Chiefs in the seventh game, the Giants were then defeated by the Kelowna Rockets in six games in the semi-finals.
 In 17 post-season games, Kane accumulated 15 points.
Kane was drafted 19th overall in the 2006 WHL Bantam Draft by the Vancouver Giants. He received his first WHL call-up for a game against the Seattle Thunderbirds on December 13, 2006, due to other Giants players international commitments in the World Junior Championships. Kane scored his first WHL goal, a game-tying marker, on March 25, 2007, the last game of the regular season. He also suited up for five WHL post-season games, being originally called up for the playoffs after Giants forward Tim Kraus was suspended for game three of the opening round. He later appeared in two Memorial Cup games, tallying an assist, as part of the Giants' 2007 Memorial Cup championship.
Set to begin his rookie campaign with the Giants the following season, Kane experienced a minor setback, as he was forced to miss the start of training camp with a case of mononucleosis. He nevertheless recovered and joined the Giants full-time to tally 24 goals – third in team scoring – and 41 points in his first WHL season.  Finishing tenth in rookie scoring, he was nominated for the Jim Piggott Memorial Trophy as WHL rookie of the year, which was awarded to Brayden Schenn of the Brandon Wheat Kings.
Kane emerged with an impressive start to the 2008–09 season, registering at least a point in each of his first 22 games. After recording his first WHL hat-trick on October 10, 2008, against the Kelowna Rockets, he was named WHL Player of the Week on October 12, succeeding linemate Casey Pierro-Zabotel, who had been chosen the previous week. Kane earned a spot as an injury replacement at the 2009 World Junior Championships with Team Canada.  Upon returning with a gold medal, Kane was named player of the week for the second time in the season on January 12, 2009, after scoring six points in two games immediately following the World Juniors. Later that month, he participated in the 2009 CHL Top Prospects Game as captain for Team Cherry.
Kane finished his second WHL season with 48 goals and 96 points, fourth in League scoring. He surpassed Adam Courchaine's team record of 43 goals in a single season, set in 2002–03. Second in team scoring to Pierro-Zabotel's 115 points, the linemates finished one-two in all-time Giants' single-season scoring as Pierro-Zabotel and Kane both surpassed Gilbert Brulé's previous 87-point mark. Kane received WHL West First Team All-Star honours along with teammates Pierro-Zabotel and Jonathon Blum. In the subsequent 2009 playoffs, after the Giants swept the Prince George Cougars in the first round, Kane scored a double-overtime game-winner to force a seventh game in the second round against the Spokane Chiefs. After eliminating the Chiefs in the seventh game, the Giants were then defeated by the Kelowna Rockets in six games in the semi-finals.  In 17 post-season games, Kane accumulated 15 points.
Evander Kane