In January, she obtained an invitation to play at the Hong Kong Tennis Classic with compatriots Venus Williams and John McEnroe.
At Hobart, Oudin was defeated in the first round by fifth seed Klára Zakopalová 6–3, 7–6.
In the first round of the Australian Open, she lost to Klára Zakopalová 1–6, 6–3, 1–6.

In the Fed Cup tie against Belgium, Oudin lost her first rubber to Kim Clijsters 0–6, 4–6.
In her final rubber, she was defeated by Yanina Wickmayer 6–2, 6–0.
Belgium reached the semifinals at the Fed Cup defeating the USA 4–1.
Oudin got her first win of the year at the Open GdF Suez, where she beat Vera Dushevina in the first round 7–5, 5–7, 6–2.
In the second round, Oudin lost to eighth seed Dominika Cibulková of Slovakia.
Having reached the semifinals the year before, Oudin's ranking dropped from No.
61 to No.
72.
Oudin's next tournament was the Cellular South Cup in Memphis.
Seeded third, she won her first-round match against Anastasia Pivovarova 6–4, 6–0.
In the second round, she faced Evgeniya Rodina, only to lose 1–6, 5–7.
Oudin was unable to defend her quarterfinal points from last year and therefore saw her ranking fall from No.
72 to No.
81.
At the Abierto Mexicano Telcel, she retired from her first-round match against qualifier Lesia Tsurenko.
Ranked 82 at the Monterrey Open, Oudin won her first-round match over fellow American Vania King 6–4, 6–1.
She was defeated in the second round by second seed and eventual champion Anastasia Pavlyuchenkova.
Ranked 84 at the BNP Paribas Open, Oudin won her first-round match over Elena Vesnina.
She was eliminated in the second round by 23rd seed Yanina Wickmayer.
Moving on to the Sony Ericsson Open, Oudin started the tournament well with a first-round win over Julia Görges.
She was defeated in the second round by 29th seed Daniela Hantuchová 6–1, 6–3.

Oudin began her clay-court season at the Family Circle Cup.
She lost in the first round to Tamira Paszek.
In the 2011 Fed Cup World Group Play-offs tie versus Germany, Oudin lost both of her rubbers to Julia Görges and Andrea Petkovic.
Germany defeated the USA 5–0.
As a result, the USA was out of the World Group for the first time.
Ranked 93 at the Grand Prix SAR La Princesse Lalla Meryem, Oudin upset third seed Lourdes Domínguez Lino in the first round 4–6, 6–1, 6–2.
She reached the quarterfinals when her second round opponent, Polona Hercog, withdrew due to an ankle injury.
In the quarterfinals, Oudin lost to eventual champion Alberta Brianti.
At the Estoril Open, Oudin lost in the first round to qualifier and fellow American Sloane Stephens 2–6, 1–6.
Competing in her final tournament before the French Open at the Internationaux de Strasbourg, Oudin was defeated in the first round by seventh seed Anabel Medina Garrigues 6–3, 6–1.
Ranked 88 at the French Open, Oudin lost in the first round to fifth seed and defending champion Francesca Schiavone 2–6, 0–6.

Oudin started her grass court season at the Aegon Trophy.
Seeded fourth, she lost in the second round to Sloane Stephens .
At the e-Boks Sony Ericsson Open, a tournament that is not on grass, Oudin was defeated in the first round by Michaëlla Krajicek.
Playing qualifying at the Aegon International, Oudin lost in the final round of qualifying to Zheng Jie 1–6, 4–6.
Ranked 87 at the Wimbledon Championships, Oudin was defeated in the first round by 18th seed Ana Ivanovic 6–0, 6–1.

As the top seed at the Fifth Third Bank Tennis Championships, Oudin was defeated in the first round by Chanel Simmonds.
Oudin started her US Open Series by competing at the first edition of the Citi Open.
She lost in the first round to third seed Tamira Paszek.
At the Mercury Insurance Open, Oudin was crushed in the first round by Elena Baltacha 6–0, 6–1.
Oudin lost in the first round of qualifying at the Rogers Cup and the Western & Southern Open to fifth seed Bojana Jovanovski 4–6, 2–6 and 15th seed Kateryna Bondarenko 1–6, 4–6.
In her next tournament, Oudin received a wild-card entry into the singles main draw at the first edition of the Texas Tennis Open.
In the first round, she was up against lu
In January, she obtained an invitation to play at the Hong Kong Tennis Classic with compatriots Venus Williams and John McEnroe. At Hobart, Oudin was defeated in the first round by fifth seed Klára Zakopalová 6–3, 7–6. In the first round of the Australian Open, she lost to Klára Zakopalová 1–6, 6–3, 1–6.
In the Fed Cup tie against Belgium, Oudin lost her first rubber to Kim Clijsters 0–6, 4–6. In her final rubber, she was defeated by Yanina Wickmayer 6–2, 6–0. Belgium reached the semifinals at the Fed Cup defeating the USA 4–1. Oudin got her first win of the year at the Open GdF Suez, where she beat Vera Dushevina in the first round 7–5, 5–7, 6–2. In the second round, Oudin lost to eighth seed Dominika Cibulková of Slovakia. Having reached the semifinals the year before, Oudin's ranking dropped from No. 61 to No. 72. Oudin's next tournament was the Cellular South Cup in Memphis. Seeded third, she won her first-round match against Anastasia Pivovarova 6–4, 6–0. In the second round, she faced Evgeniya Rodina, only to lose 1–6, 5–7. Oudin was unable to defend her quarterfinal points from last year and therefore saw her ranking fall from No. 72 to No. 81. At the Abierto Mexicano Telcel, she retired from her first-round match against qualifier Lesia Tsurenko. Ranked 82 at the Monterrey Open, Oudin won her first-round match over fellow American Vania King 6–4, 6–1. She was defeated in the second round by second seed and eventual champion Anastasia Pavlyuchenkova. Ranked 84 at the BNP Paribas Open, Oudin won her first-round match over Elena Vesnina. She was eliminated in the second round by 23rd seed Yanina Wickmayer. Moving on to the Sony Ericsson Open, Oudin started the tournament well with a first-round win over Julia Görges. She was defeated in the second round by 29th seed Daniela Hantuchová 6–1, 6–3.
Oudin began her clay-court season at the Family Circle Cup. She lost in the first round to Tamira Paszek. In the 2011 Fed Cup World Group Play-offs tie versus Germany, Oudin lost both of her rubbers to Julia Görges and Andrea Petkovic. Germany defeated the USA 5–0. As a result, the USA was out of the World Group for the first time. Ranked 93 at the Grand Prix SAR La Princesse Lalla Meryem, Oudin upset third seed Lourdes Domínguez Lino in the first round 4–6, 6–1, 6–2. She reached the quarterfinals when her second round opponent, Polona Hercog, withdrew due to an ankle injury. In the quarterfinals, Oudin lost to eventual champion Alberta Brianti. At the Estoril Open, Oudin lost in the first round to qualifier and fellow American Sloane Stephens 2–6, 1–6. Competing in her final tournament before the French Open at the Internationaux de Strasbourg, Oudin was defeated in the first round by seventh seed Anabel Medina Garrigues 6–3, 6–1. Ranked 88 at the French Open, Oudin lost in the first round to fifth seed and defending champion Francesca Schiavone 2–6, 0–6.
Oudin started her grass court season at the Aegon Trophy. Seeded fourth, she lost in the second round to Sloane Stephens . At the e-Boks Sony Ericsson Open, a tournament that is not on grass, Oudin was defeated in the first round by Michaëlla Krajicek. Playing qualifying at the Aegon International, Oudin lost in the final round of qualifying to Zheng Jie 1–6, 4–6. Ranked 87 at the Wimbledon Championships, Oudin was defeated in the first round by 18th seed Ana Ivanovic 6–0, 6–1.
As the top seed at the Fifth Third Bank Tennis Championships, Oudin was defeated in the first round by Chanel Simmonds. Oudin started her US Open Series by competing at the first edition of the Citi Open. She lost in the first round to third seed Tamira Paszek. At the Mercury Insurance Open, Oudin was crushed in the first round by Elena Baltacha 6–0, 6–1. Oudin lost in the first round of qualifying at the Rogers Cup and the Western & Southern Open to fifth seed Bojana Jovanovski 4–6, 2–6 and 15th seed Kateryna Bondarenko 1–6, 4–6. In her next tournament, Oudin received a wild-card entry into the singles main draw at the first edition of the Texas Tennis Open. In the first round, she was up against lu
Melanie Oudin