James Ohio Pattie, along with a group of American trappers and mountain men, may have been the next European to reach the canyon, in 1826.

Jacob Hamblin, a Mormon missionary, was sent by Brigham Young in the 1850s to locate suitable river crossing sites in the canyon.
Building good relations with local Hualapai and white settlers, he found the Crossing of the Fathers, and the locations that would become Lees Ferry in 1858 and Pearce Ferry (later operated by, and named for, Harrison Pearce) – only the latter two sites suitable for ferry operation.
He also acted as an advisor to John Wesley Powell, before his second expedition to the Grand Canyon, serving as a diplomat between Powell and the local native tribes to ensure the safety of his party.

In 1857, Edward Fitzgerald Beale was superintendent of an expedition to survey a wagon road along the 35th parallel from Fort Defiance, Arizona to the Colorado River.
He led a small party of men in search of water on the Coconino Plateau near the canyon's south rim.
On September 19, near present-day National Canyon, they came upon what May Humphreys Stacey described in his journal as "...a wonderful canyon four thousand feet deep.
Everyone (in the party) admitted that he never before saw anything to match or equal this astonishing natural curiosity."

Also in 1857, the U.S. War Department asked Lieutenant Joseph Ives to lead an expedition to assess the feasibility of an up-river navigation from the Gulf of California.
Also in a stern wheeler steamboat Explorer, after two months and 350 miles (560 km) of difficult navigation, his party reached Black Canyon some two months after George Johnson.
The Explorer struck a rock and was abandoned.
Ives led his party east into the canyon — they may have been the first Europeans to travel the Diamond Creek drainage and traveled eastwards along the south rim.
In his "Colorado River of the West" report to the Senate in 1861 he states that "One or two trappers profess to have seen the canyon."

According to the San Francisco Herald, in a series of articles run in 1853, Captain Joseph R. Walker in January 1851 with his nephew James T. Walker and six men, traveled up the Colorado River to a point where it joined the Virgin River and continued east into Arizona, traveling along the Grand Canyon and making short exploratory side trips along the way.
Walker is reported to have said he wanted to visit the "Moqui" Indians, as the Hopi were then called by Europeans.
He had met these people briefly in previous years, thought them exceptionally interesting and wanted to become better acquainted.
The Herald reporter then stated, "We believe that Captain Joe Walker is the only white man in this country that has ever visited this strange people."

In 1858, John Strong Newberry became probably the first geologist to visit the Grand Canyon.

In 1869, Major John Wesley Powell led the first expedition down the canyon.
Powell set out to explore the Colorado River and the Grand Canyon.
Powell ordered a shipwright to build four reinforced Whitewall rowboats from Chicago and had them shipped east on the newly completed Continental railroad.
He hired nine men, including his brother Walter, and collected provisions for ten months.
They set out from Green River, Wyoming on May 24.
Passing through (or portaging around) a series of dangerous rapids, the group passed down the Green River to its confluence with the Colorado River, near present-day Moab, Utah.
Most of their food spoiled after getting wet in the waves or by heavy rains.
Beaten up by ferocious whitewater and nearly out of food, three men left the expedition in the Grand Canyon, electing to walk 75 miles (121 km) out across a desert to a Mormon settlement.
Never seen again, their disappearance remains one of the most enduring mysteries of American western history.
The remaining members completed the journey through the Grand Canyon on August 13, 1869.
In 1871 Powell first used the term "Grand Canyon"; previously it had been called the "Big Canyon".

In 1889, Frank M. Brown wanted to build a railroad along the Colora
James Ohio Pattie, along with a group of American trappers and mountain men, may have been the next European to reach the canyon, in 1826.
Jacob Hamblin, a Mormon missionary, was sent by Brigham Young in the 1850s to locate suitable river crossing sites in the canyon. Building good relations with local Hualapai and white settlers, he found the Crossing of the Fathers, and the locations that would become Lees Ferry in 1858 and Pearce Ferry (later operated by, and named for, Harrison Pearce) – only the latter two sites suitable for ferry operation. He also acted as an advisor to John Wesley Powell, before his second expedition to the Grand Canyon, serving as a diplomat between Powell and the local native tribes to ensure the safety of his party.
In 1857, Edward Fitzgerald Beale was superintendent of an expedition to survey a wagon road along the 35th parallel from Fort Defiance, Arizona to the Colorado River. He led a small party of men in search of water on the Coconino Plateau near the canyon's south rim. On September 19, near present-day National Canyon, they came upon what May Humphreys Stacey described in his journal as "...a wonderful canyon four thousand feet deep. Everyone (in the party) admitted that he never before saw anything to match or equal this astonishing natural curiosity."
Also in 1857, the U.S. War Department asked Lieutenant Joseph Ives to lead an expedition to assess the feasibility of an up-river navigation from the Gulf of California. Also in a stern wheeler steamboat Explorer, after two months and 350 miles (560 km) of difficult navigation, his party reached Black Canyon some two months after George Johnson. The Explorer struck a rock and was abandoned. Ives led his party east into the canyon — they may have been the first Europeans to travel the Diamond Creek drainage and traveled eastwards along the south rim. In his "Colorado River of the West" report to the Senate in 1861 he states that "One or two trappers profess to have seen the canyon."
According to the San Francisco Herald, in a series of articles run in 1853, Captain Joseph R. Walker in January 1851 with his nephew James T. Walker and six men, traveled up the Colorado River to a point where it joined the Virgin River and continued east into Arizona, traveling along the Grand Canyon and making short exploratory side trips along the way. Walker is reported to have said he wanted to visit the "Moqui" Indians, as the Hopi were then called by Europeans. He had met these people briefly in previous years, thought them exceptionally interesting and wanted to become better acquainted. The Herald reporter then stated, "We believe that Captain Joe Walker is the only white man in this country that has ever visited this strange people."
In 1858, John Strong Newberry became probably the first geologist to visit the Grand Canyon.
In 1869, Major John Wesley Powell led the first expedition down the canyon. Powell set out to explore the Colorado River and the Grand Canyon. Powell ordered a shipwright to build four reinforced Whitewall rowboats from Chicago and had them shipped east on the newly completed Continental railroad. He hired nine men, including his brother Walter, and collected provisions for ten months. They set out from Green River, Wyoming on May 24. Passing through (or portaging around) a series of dangerous rapids, the group passed down the Green River to its confluence with the Colorado River, near present-day Moab, Utah. Most of their food spoiled after getting wet in the waves or by heavy rains. Beaten up by ferocious whitewater and nearly out of food, three men left the expedition in the Grand Canyon, electing to walk 75 miles (121 km) out across a desert to a Mormon settlement. Never seen again, their disappearance remains one of the most enduring mysteries of American western history. The remaining members completed the journey through the Grand Canyon on August 13, 1869. In 1871 Powell first used the term "Grand Canyon"; previously it had been called the "Big Canyon".
In 1889, Frank M. Brown wanted to build a railroad along the Colora
Grand Canyon