Syrrako was inhabited before the 15th century (possibly in the 11th century) by Aromanians (Vlachs).
Evidence for this includes the age of the plane trees in the village square.
During the Ottoman period, after 1480, it was the capital of the self-governed federation of Malakasioi, consisting of 42 villages and belonging to the Valide Sultan.
Because of this it enjoyed a privileged treatment.
During that time the village developed immensely.
Firstly, the inhabitants were involved in cattle breeding and afterwards they developed trade, industrial production of wool textiles and cattle products.

The expanse of pasture land (nearly 750 kmª) enabled the inhabitants to raise the number of sheep and goats to thousands (50,000 and according to others 75,000) and bring the big quantity of their products, in connection with the Syrrakiotes’ trade genius, to the biggest trade centers in the Mediterranean and Black Sea (Italy, France, Spain, Odessa, Moscow, Bucharest, Belgrade, Constantinople and others).

Capes made in Syrrako were in great demand and it is said that even Napoleon’s army was supplied with a large number of them.
The travellers Leake and François Pouqueville report in the years 1815 and 1818 that they found in Syrrako “a trade cycle comparable to the best European cities”.
Furthermore, they mention the existence of significant libraries and the circulation of European newspapers, evidence that intellectual development co-existed with trade.
Syrrako and Kalarrytes were the only villages in Epirus that took part in the first year of the 1821 Revolution with 720 families and 3,500 inhabitants.
The Ottomans destroyed and burnt down the village, and the inhabitants abandoned it trying to save their lives (10 July 1821).

Only five buildings remained untouched, among them the church of the Panagia.
The inhabitants returned in the year 1825 (according to others in 1827-28), rebuilt the village and between 1860-70 the village became again as imposing as in the previous years.
A second revolution took place in 1854 which was of no consequence.
The decline of the wool trade and its replacement by other fibers (1908–10) hurt the local economy and led to changes in production patterns.
At that time 530 houses and nearly 5,000 inhabitants existed in the village.

In the aftermath of the First Balkan War, Syrrako was joined to Greece on November 23, 1912.
In the national census of 1913, Ioannina counts 17,000 inhabitants, Konitsa 2,000 and Syrrako 3,500.
Syrrako was inhabited before the 15th century (possibly in the 11th century) by Aromanians (Vlachs). Evidence for this includes the age of the plane trees in the village square. During the Ottoman period, after 1480, it was the capital of the self-governed federation of Malakasioi, consisting of 42 villages and belonging to the Valide Sultan. Because of this it enjoyed a privileged treatment. During that time the village developed immensely. Firstly, the inhabitants were involved in cattle breeding and afterwards they developed trade, industrial production of wool textiles and cattle products.
The expanse of pasture land (nearly 750 kmª) enabled the inhabitants to raise the number of sheep and goats to thousands (50,000 and according to others 75,000) and bring the big quantity of their products, in connection with the Syrrakiotes’ trade genius, to the biggest trade centers in the Mediterranean and Black Sea (Italy, France, Spain, Odessa, Moscow, Bucharest, Belgrade, Constantinople and others).
Capes made in Syrrako were in great demand and it is said that even Napoleon’s army was supplied with a large number of them. The travellers Leake and François Pouqueville report in the years 1815 and 1818 that they found in Syrrako “a trade cycle comparable to the best European cities”. Furthermore, they mention the existence of significant libraries and the circulation of European newspapers, evidence that intellectual development co-existed with trade. Syrrako and Kalarrytes were the only villages in Epirus that took part in the first year of the 1821 Revolution with 720 families and 3,500 inhabitants. The Ottomans destroyed and burnt down the village, and the inhabitants abandoned it trying to save their lives (10 July 1821).
Only five buildings remained untouched, among them the church of the Panagia. The inhabitants returned in the year 1825 (according to others in 1827-28), rebuilt the village and between 1860-70 the village became again as imposing as in the previous years. A second revolution took place in 1854 which was of no consequence. The decline of the wool trade and its replacement by other fibers (1908–10) hurt the local economy and led to changes in production patterns. At that time 530 houses and nearly 5,000 inhabitants existed in the village.
In the aftermath of the First Balkan War, Syrrako was joined to Greece on November 23, 1912. In the national census of 1913, Ioannina counts 17,000 inhabitants, Konitsa 2,000 and Syrrako 3,500.
Syrrako