In 1373 Fürstenwalde upon Spree became the new seat of the cathedral of the see of Lebus, one of the three medieval dioceses of the March of Brandenburg.
The cathedral, which is dedicated to Our Lady, was raised to cathedral of the diocese.
In 1446, the cathedral was ransacked by Hussites.
The attack was aimed at bishop John V of Lebus, a strong critic of Jan Hus.
After the Hussites laid the cathedral to waste, work began on building it anew.

In 1517, bishop Dietrich von Bülow commissioned the sculptor Franz Maidburg to build a sacrament house (Sakramentshaus), a type of freestanding tabernacle that emerged from the German Gothic architecture of the late 14th to early 15th century.
This part of the cathedral's history is controversial, as some believe that Maidburg did not work on this cathedral.

The cathedral weathered another attack during World War II, when it was almost completely destroyed.
However, the church was not left completely at the mercy of the War's bombing.
Foresight and precaution had prevailed, and the sacrament house and numerous grave-slabs had been walled in to protect them in 1942.
This precautionary measure saved these structures from facing the same fate as the main church.
The sacrament house and the grave-slabs thus protected survive to this day.
In 1373 Fürstenwalde upon Spree became the new seat of the cathedral of the see of Lebus, one of the three medieval dioceses of the March of Brandenburg. The cathedral, which is dedicated to Our Lady, was raised to cathedral of the diocese. In 1446, the cathedral was ransacked by Hussites. The attack was aimed at bishop John V of Lebus, a strong critic of Jan Hus. After the Hussites laid the cathedral to waste, work began on building it anew.
In 1517, bishop Dietrich von Bülow commissioned the sculptor Franz Maidburg to build a sacrament house (Sakramentshaus), a type of freestanding tabernacle that emerged from the German Gothic architecture of the late 14th to early 15th century. This part of the cathedral's history is controversial, as some believe that Maidburg did not work on this cathedral.
The cathedral weathered another attack during World War II, when it was almost completely destroyed. However, the church was not left completely at the mercy of the War's bombing. Foresight and precaution had prevailed, and the sacrament house and numerous grave-slabs had been walled in to protect them in 1942. This precautionary measure saved these structures from facing the same fate as the main church. The sacrament house and the grave-slabs thus protected survive to this day.
St Mary's Cathedral, Fürstenwalde