LiPo cells are affected by the same problems as other lithium-ion cells.
This means that overcharge, over-discharge, over-temperature, short circuit, crush and nail penetration may all result in a catastrophic failure, including the pouch rupturing, the electrolyte leaking, and fire.

All Li-ion cells expand at high levels of state of charge (SOC) or over-charge, due to slight vaporisation of the electrolyte.
This may result in delamination, and thus bad contact of the internal layers of the cell, which in turn brings diminished reliability and overall cycle life of the cell.
This is very noticeable for LiPos, which can visibly inflate due to lack of a hard case to contain their expansion.

For a comparison with LFP cells on this subject, please see LiFe cell safety
LiPo cells are affected by the same problems as other lithium-ion cells. This means that overcharge, over-discharge, over-temperature, short circuit, crush and nail penetration may all result in a catastrophic failure, including the pouch rupturing, the electrolyte leaking, and fire.
All Li-ion cells expand at high levels of state of charge (SOC) or over-charge, due to slight vaporisation of the electrolyte. This may result in delamination, and thus bad contact of the internal layers of the cell, which in turn brings diminished reliability and overall cycle life of the cell. This is very noticeable for LiPos, which can visibly inflate due to lack of a hard case to contain their expansion.
For a comparison with LFP cells on this subject, please see LiFe cell safety
Lithium polymer battery