Commuter Rail trains run to South Station from towns like:
Plymouth
Worcester
Providence, Rhode Island (including a stop at T.F. Green Airport)
When the New England Patriots are playing at home, the MBTA runs special Commuter Rail trains to Gillette Stadium from both South Station and T.F. Green Airport.

Closer to Boston, Commuter Rail trains stop at a few different Boston neighborhoods on their way to South Station, like Back Bay, Jamaica Plain, Hyde Park, and Dorchester.
 
Travelers can change to the MBTA's Red Line subway at South Station.
Commuter Rail trains run to South Station from towns like:
Plymouth
Worcester
Providence, Rhode Island (including a stop at T.F. Green Airport)
When the New England Patriots are playing at home, the MBTA runs special Commuter Rail trains to Gillette Stadium from both South Station and T.F. Green Airport.
Closer to Boston, Commuter Rail trains stop at a few different Boston neighborhoods on their way to South Station, like Back Bay, Jamaica Plain, Hyde Park, and Dorchester.  
Travelers can change to the MBTA's Red Line subway at South Station.
Massachusetts Bay Transportation Authority