On April 11, 2016, McCann suffered a Grade 2 right ankle sprain and was placed on the disabled list.
On May 31, 2016, McCann's Major League record of 139 games to start a career at catcher without committing an error ended.

For the 2016 season, McCann batted .221 with 12 home runs and 48 RBI in 105 games.
Following the season, McCann was named a Gold Glove Award finalist for catcher, along with Carlos Pérez and Salvador Pérez.
McCann threw out 45 percent of would-be base stealers, second-highest among AL catchers, and led his position with nine double plays.
His 9 Defensive Runs Saved rating also ranked second in the AL.
On April 11, 2016, McCann suffered a Grade 2 right ankle sprain and was placed on the disabled list. On May 31, 2016, McCann's Major League record of 139 games to start a career at catcher without committing an error ended.
For the 2016 season, McCann batted .221 with 12 home runs and 48 RBI in 105 games. Following the season, McCann was named a Gold Glove Award finalist for catcher, along with Carlos Pérez and Salvador Pérez. McCann threw out 45 percent of would-be base stealers, second-highest among AL catchers, and led his position with nine double plays. His 9 Defensive Runs Saved rating also ranked second in the AL.
James McCann (baseball)