Clifford was a musician and soprano singer and gave concerts as a young woman.
She was hired to teach at South San Francisco High School in 1912, as one of the school's first three teachers, and eventually became the school's Dean of Girls.
She started and coached the school's track teams, built the soccer, basketball, field hockey, and volleyball programs, directed the school musical and the glee club, and wrote the school song. "
She has been a perennial committee-of-one to see practically every local football practice and game, to praise the players, to award weekly athletic awards, and to banquet the players at the end of the season", noted a local newspaper when she retired in 1955.

Clifford was a charter member of the South San Francisco Women's Club, and active in the American Association of University Women branch in San Mateo.
She rode horseback to collect signatures for a Carnegie grant, to build a library in South San Francisco; Grand Avenue Library opened in 1916.
She served as secretary of the library commission for almost forty years.
She was co-chair of the South San Francisco Hospitality House during World War II, and she was active in the San Mateo County Historical Association.
She donated her grandfather William Edgar Randall's diaries of the Gold Rush era, and other Randall family papers, to the Bancroft Library in 1955.

Clifford was an advocate of prohibition, and in 1932 objected when the San Mateo County Board of Supervisors when they supported legalizing wine and beer.
Clifford was a musician and soprano singer and gave concerts as a young woman. She was hired to teach at South San Francisco High School in 1912, as one of the school's first three teachers, and eventually became the school's Dean of Girls. She started and coached the school's track teams, built the soccer, basketball, field hockey, and volleyball programs, directed the school musical and the glee club, and wrote the school song. "She has been a perennial committee-of-one to see practically every local football practice and game, to praise the players, to award weekly athletic awards, and to banquet the players at the end of the season", noted a local newspaper when she retired in 1955.
Clifford was a charter member of the South San Francisco Women's Club, and active in the American Association of University Women branch in San Mateo. She rode horseback to collect signatures for a Carnegie grant, to build a library in South San Francisco; Grand Avenue Library opened in 1916. She served as secretary of the library commission for almost forty years. She was co-chair of the South San Francisco Hospitality House during World War II, and she was active in the San Mateo County Historical Association. She donated her grandfather William Edgar Randall's diaries of the Gold Rush era, and other Randall family papers, to the Bancroft Library in 1955.
Clifford was an advocate of prohibition, and in 1932 objected when the San Mateo County Board of Supervisors when they supported legalizing wine and beer.
Rue Randall Clifford