On 1 August 1848, the Saxon-Bohemian State Railway (Sächsisch-Böhmische Staatseisenbahn) opened the Bohemian station as the terminus of its line, which only extended to Pirna.
It was initially only a barn-like half-timbered building spanning four tracks and it also had a makeshift locomotive depot, carriage sheds and workshops.

The opening ceremony took place on 6 April 1851, coinciding with the extension of the line to Bodenbach (now Děčín).
A year later the opening of the Marienbrücke (Maria Bridge) for road and rail traffic on 19 April 1852 allowed the operation of traffic through the Bohemian station to the Leipziger station and the Silesian Station on the Neustadt side of the Elbe.

From 1861 to 1864, the passenger infrastructure was moved to the west, to make room for a new building.
On 1 August 1864, a solid new entrance building replaced the previous provisional building  Four 184 metre long wings, which were designed by Karl Moritz Haenel and Carl Adolph Canzler in the form of Italian Renaissance buildings, were annexed.
The main platform could handle two trains simultaneous at first, but it was only 370 metres long.
An additional 360-metre-long island platform was built between 1871 and 1872.
This extension had become necessary because in 1869 the Bohemian station took over the passenger traffic of the Dresden–Werdau railway from the Albert Station, which was located about two kilometres to the northwest and subsequently only served coal traffic.
In order to handle the traffic towards Chemnitz a new main station (Hauptbahnhof) was built in front of the Bohemian station.
In addition, the new Hauptbahnhof would handle the passenger traffic of the Berliner station, which was also located in the Old Town (Altstädt) on the south side of the Elbe, but almost three kilometres to the northwest.
On 1 August 1848, the Saxon-Bohemian State Railway (Sächsisch-Böhmische Staatseisenbahn) opened the Bohemian station as the terminus of its line, which only extended to Pirna. It was initially only a barn-like half-timbered building spanning four tracks and it also had a makeshift locomotive depot, carriage sheds and workshops.
The opening ceremony took place on 6 April 1851, coinciding with the extension of the line to Bodenbach (now Děčín). A year later the opening of the Marienbrücke (Maria Bridge) for road and rail traffic on 19 April 1852 allowed the operation of traffic through the Bohemian station to the Leipziger station and the Silesian Station on the Neustadt side of the Elbe.
From 1861 to 1864, the passenger infrastructure was moved to the west, to make room for a new building. On 1 August 1864, a solid new entrance building replaced the previous provisional building  Four 184 metre long wings, which were designed by Karl Moritz Haenel and Carl Adolph Canzler in the form of Italian Renaissance buildings, were annexed.The main platform could handle two trains simultaneous at first, but it was only 370 metres long. An additional 360-metre-long island platform was built between 1871 and 1872. This extension had become necessary because in 1869 the Bohemian station took over the passenger traffic of the Dresden–Werdau railway from the Albert Station, which was located about two kilometres to the northwest and subsequently only served coal traffic. In order to handle the traffic towards Chemnitz a new main station (Hauptbahnhof) was built in front of the Bohemian station. In addition, the new Hauptbahnhof would handle the passenger traffic of the Berliner station, which was also located in the Old Town (Altstädt) on the south side of the Elbe, but almost three kilometres to the northwest.
Dresden Hauptbahnhof