In 1880, Upton's father was elected as a member of the United States Congress as a Republican from Ohio, succeeding President James Garfield in the position.
This entrance into the world of high politics provided Harriet with an opportunity to meet leading political leaders of the day, including Susan B. Anthony — the person who brought Upton into the movement to win the right to vote for women.

Upton was a key organizer and the first president of the Suffrage Association of Warren.
She was also a member of the National American Woman Suffrage Association (NAWSA) from 1890.
In 1891, Upton hosted a conclave of women seeking equal rights with men, Ohio Women in Convention, in her home.

In 1894, Upton was elected as the treasurer of the NAWSA, the leading national woman suffrage organization.
She brought the headquarters of that organization home to Warren, Ohio, from 1903 to 1910, the end of her tenure in that position.
Additionally, Upton served as president of the Ohio Woman Suffrage Association from 1899 to 1908 and again from 1911 to 1920.

In 1920, Upton was elected Vice Chairman of the Executive Committee of the Republican National Committee.
She was the first woman to serve on that highest national body of Republican Party politics.
She stepped down from this position in June 1924 in an attempt to follow her father into the halls of Congress, running unsuccessfully in the August Republican primary election in the Ohio 19th District for the House of Representatives.

In 1928 Upton served as the assistant campaign manager for the Republican Party of Ohio.
For all her successes and honors on the national stage, Upton's personal electoral success was modest, being the first woman to be elected to the Warren Board of Education.

Throughout her life Upton participated in a number of other organizations, including the Daughters of the American Revolution, the Woman's Christian Temperance Union, the Women's Relief Corps, and the Episcopal Church.
In 1880, Upton's father was elected as a member of the United States Congress as a Republican from Ohio, succeeding President James Garfield in the position. This entrance into the world of high politics provided Harriet with an opportunity to meet leading political leaders of the day, including Susan B. Anthony — the person who brought Upton into the movement to win the right to vote for women.
Upton was a key organizer and the first president of the Suffrage Association of Warren. She was also a member of the National American Woman Suffrage Association (NAWSA) from 1890. In 1891, Upton hosted a conclave of women seeking equal rights with men, Ohio Women in Convention, in her home.
In 1894, Upton was elected as the treasurer of the NAWSA, the leading national woman suffrage organization. She brought the headquarters of that organization home to Warren, Ohio, from 1903 to 1910, the end of her tenure in that position. Additionally, Upton served as president of the Ohio Woman Suffrage Association from 1899 to 1908 and again from 1911 to 1920.
In 1920, Upton was elected Vice Chairman of the Executive Committee of the Republican National Committee. She was the first woman to serve on that highest national body of Republican Party politics. She stepped down from this position in June 1924 in an attempt to follow her father into the halls of Congress, running unsuccessfully in the August Republican primary election in the Ohio 19th District for the House of Representatives.
In 1928 Upton served as the assistant campaign manager for the Republican Party of Ohio. For all her successes and honors on the national stage, Upton's personal electoral success was modest, being the first woman to be elected to the Warren Board of Education.
Throughout her life Upton participated in a number of other organizations, including the Daughters of the American Revolution, the Woman's Christian Temperance Union, the Women's Relief Corps, and the Episcopal Church.
Harriet Taylor Upton