After college, Liotta moved to New York City.
He got a job as a bartender at the Shubert Organization and landed an agent within six months.
One of his earliest roles was as Joey Perrini on the soap opera Another World, on which he appeared from 1978 to 1981.
He quit the show so he could try his luck in the film industry and moved to Los Angeles.
He made his film debut in 1983's The Lonely Lady.
His first major acting role was Something Wild (1986), which earned him his first Golden Globe nomination.
In 1989, Liotta portrayed the ghost of famed baseball player Shoeless Joe Jackson in the fantasy/drama film Field of Dreams.

In 1990, Liotta portrayed real-life mobster Henry Hill in Martin Scorsese's critically acclaimed and commercially successful film Goodfellas.
In 1992, he starred as a psychopathic cop in the thriller Unlawful Entry.
He appeared in a leading role in the science-fiction/action film No Escape.
In 1996, he starred in the sci-fi/thriller Unforgettable.
Liotta earned critical praise for his turn in James Mangold's 1997 film Cop Land, and he received critical praise in 1998 for his performance as a compulsive gambler in Phoenix.

In addition to his film roles, Liotta portrayed singer Frank Sinatra in the 1998 TV movie The Rat Pack (for which he received a Screen Actors Guild award nomination), starred as himself in the sitcom Just Shoot Me in December 2001 & January 2002, provided the voice of Tommy Vercetti for the 2002 video game Grand Theft Auto: Vice City, and appeared in the television drama ER in 2004, playing Charlie Metcalf in the episode "Time of Death".
The ER role earned Liotta an Emmy for Outstanding Guest Actor in a Drama Series (Liotta later spoofed himself and his Emmy win in Bee Movie).
Liotta starred in the 2006 CBS television series Smith, which was pulled from the schedule after three episodes, and in 2012 Liotta appeared as himself in a purely vocal role for the "What a Croc!"
episode of the Disney Channel comedy series Phineas & Ferb.

Liotta played the father of drug dealer George Jung in the 2001 Johnny Depp film Blow and, in the following year, appeared as Detective Lieutenant Henry Oak in the Joe Carnahan-directed film Narc, a role that led to an Independent Spirit Award nomination and a Phoenix Film Critics Society Awards nomination for Best Supporting Male.

He then reunited with director James Mangold in 2003, alongside John Cusack and Alfred Molina, in the dark horror-thriller Identity.
In 2005, he narrated Inside the Mafia for the National Geographic Channel.
He later appeared in Smokin' Aces—reuniting with Narc director Carnahan, in which he portrayed an FBI agent named Donald Carruthers in one of the lead roles.

Liotta appeared with John Travolta in the movie Wild Hogs, in Battle in Seattle as the city's mayor, and in 2008, starred in Hero Wanted as a detective alongside Cuba Gooding Jr. Also in 2008, he made a guest appearance on the SpongeBob SquarePants episode "What Ever Happened to SpongeBob?";
in the episode, he voices the sadistic leader of a gang called the Bubble Poppin’ Boys, who try to kill an amnesiac SpongeBob (voiced by Tom Kenny) because bubble blowing is illegal in New Kelp City, but they get blown away by him, and SpongeBob becomes the new mayor of the city; the episode also had Liotta work with another legendary actor, Clancy Brown, who voices Mr. Krabs on the show, although their characters don't share any screen credit.
He also appeared in Crossing Over, co-starring Harrison Ford.
Liotta played Detective Harrison in the 2009 Jody Hill comedy Observe and Report as Seth Rogen's nemesis from the local police.
In 2011, he starred in The Son of No One, opposite Channing Tatum, and for the first time in his career, Al Pacino.

In 2004, Liotta made his Broadway debut opposite Frank Langella in the Stephen Belber play, Match.

In the 2010s, Liotta appeared in Date Night, with Steve Carell, Charlie St. Cloud with Zac Efron, the independent drama Snowmen, and The River Sorrow, which stars Liotta as a detective alongside Christian Slater and Ving Rhames.
He starred alongsid
After college, Liotta moved to New York City. He got a job as a bartender at the Shubert Organization and landed an agent within six months. One of his earliest roles was as Joey Perrini on the soap opera Another World, on which he appeared from 1978 to 1981. He quit the show so he could try his luck in the film industry and moved to Los Angeles. He made his film debut in 1983's The Lonely Lady. His first major acting role was Something Wild (1986), which earned him his first Golden Globe nomination. In 1989, Liotta portrayed the ghost of famed baseball player Shoeless Joe Jackson in the fantasy/drama film Field of Dreams.
In 1990, Liotta portrayed real-life mobster Henry Hill in Martin Scorsese's critically acclaimed and commercially successful film Goodfellas. In 1992, he starred as a psychopathic cop in the thriller Unlawful Entry. He appeared in a leading role in the science-fiction/action film No Escape. In 1996, he starred in the sci-fi/thriller Unforgettable. Liotta earned critical praise for his turn in James Mangold's 1997 film Cop Land, and he received critical praise in 1998 for his performance as a compulsive gambler in Phoenix.
In addition to his film roles, Liotta portrayed singer Frank Sinatra in the 1998 TV movie The Rat Pack (for which he received a Screen Actors Guild award nomination), starred as himself in the sitcom Just Shoot Me in December 2001 & January 2002, provided the voice of Tommy Vercetti for the 2002 video game Grand Theft Auto: Vice City, and appeared in the television drama ER in 2004, playing Charlie Metcalf in the episode "Time of Death". The ER role earned Liotta an Emmy for Outstanding Guest Actor in a Drama Series (Liotta later spoofed himself and his Emmy win in Bee Movie). Liotta starred in the 2006 CBS television series Smith, which was pulled from the schedule after three episodes, and in 2012 Liotta appeared as himself in a purely vocal role for the "What a Croc!" episode of the Disney Channel comedy series Phineas & Ferb.
Liotta played the father of drug dealer George Jung in the 2001 Johnny Depp film Blow and, in the following year, appeared as Detective Lieutenant Henry Oak in the Joe Carnahan-directed film Narc, a role that led to an Independent Spirit Award nomination and a Phoenix Film Critics Society Awards nomination for Best Supporting Male.
He then reunited with director James Mangold in 2003, alongside John Cusack and Alfred Molina, in the dark horror-thriller Identity. In 2005, he narrated Inside the Mafia for the National Geographic Channel. He later appeared in Smokin' Aces—reuniting with Narc director Carnahan, in which he portrayed an FBI agent named Donald Carruthers in one of the lead roles.
Liotta appeared with John Travolta in the movie Wild Hogs, in Battle in Seattle as the city's mayor, and in 2008, starred in Hero Wanted as a detective alongside Cuba Gooding Jr. Also in 2008, he made a guest appearance on the SpongeBob SquarePants episode "What Ever Happened to SpongeBob?"; in the episode, he voices the sadistic leader of a gang called the Bubble Poppin’ Boys, who try to kill an amnesiac SpongeBob (voiced by Tom Kenny) because bubble blowing is illegal in New Kelp City, but they get blown away by him, and SpongeBob becomes the new mayor of the city; the episode also had Liotta work with another legendary actor, Clancy Brown, who voices Mr. Krabs on the show, although their characters don't share any screen credit. He also appeared in Crossing Over, co-starring Harrison Ford. Liotta played Detective Harrison in the 2009 Jody Hill comedy Observe and Report as Seth Rogen's nemesis from the local police. In 2011, he starred in The Son of No One, opposite Channing Tatum, and for the first time in his career, Al Pacino.
In 2004, Liotta made his Broadway debut opposite Frank Langella in the Stephen Belber play, Match.
In the 2010s, Liotta appeared in Date Night, with Steve Carell, Charlie St. Cloud with Zac Efron, the independent drama Snowmen, and The River Sorrow, which stars Liotta as a detective alongside Christian Slater and Ving Rhames. He starred alongsid
Ray Liotta