Hayes had announced early in his presidency that he would not seek another term, which meant that the contest for the Republican nomination in 1880 was open to all challengers—including Blaine.
Blaine was among the early favorites for the nomination, as were former President Grant, Treasury Secretary John Sherman of Ohio, and Senator George F. Edmunds of Vermont.
Although Grant did not actively promote his candidacy, his entry into the race re-energized the Stalwarts and when the convention met in Chicago in June 1880, they instantly polarized the delegates into Grant and anti-Grant factions, with Blaine the most popular choice of the latter group.
Blaine was nominated by James Frederick Joy of Michigan, but in contrast to Ingersoll's exciting speech of 1876, Joy's lengthy oration was remembered only for its maladroitness.
After the other candidates were nominated, the first ballot showed Grant leading with 304 votes and Blaine in second with 284; no other candidate had more than Sherman's 93, and none had the required majority of 379.
Sherman's delegates could swing the nomination to either Grant or Blaine, but he refused to release them through twenty-eight ballots in the hope that the anti-Grant forces would desert Blaine and flock to him.
Eventually, they did desert Blaine, but instead of Sherman they shifted their votes to Ohio Congressman James A. Garfield, and by the thirty-sixth ballot he had 399 votes, enough for victory.

Garfield placated the Stalwarts by endorsing Chester A. Arthur of New York, a Conkling loyalist, as nominee for vice president, but it was to Blaine and his delegates that Garfield owed his nomination.
When Garfield was elected over Democrat Winfield Scott Hancock, he turned to Blaine to guide him in selection of his cabinet and offered him the preeminent position: Secretary of State.
Blaine accepted, resigning from the Senate on March 4, 1881.
Hayes had announced early in his presidency that he would not seek another term, which meant that the contest for the Republican nomination in 1880 was open to all challengers—including Blaine. Blaine was among the early favorites for the nomination, as were former President Grant, Treasury Secretary John Sherman of Ohio, and Senator George F. Edmunds of Vermont. Although Grant did not actively promote his candidacy, his entry into the race re-energized the Stalwarts and when the convention met in Chicago in June 1880, they instantly polarized the delegates into Grant and anti-Grant factions, with Blaine the most popular choice of the latter group. Blaine was nominated by James Frederick Joy of Michigan, but in contrast to Ingersoll's exciting speech of 1876, Joy's lengthy oration was remembered only for its maladroitness. After the other candidates were nominated, the first ballot showed Grant leading with 304 votes and Blaine in second with 284; no other candidate had more than Sherman's 93, and none had the required majority of 379. Sherman's delegates could swing the nomination to either Grant or Blaine, but he refused to release them through twenty-eight ballots in the hope that the anti-Grant forces would desert Blaine and flock to him. Eventually, they did desert Blaine, but instead of Sherman they shifted their votes to Ohio Congressman James A. Garfield, and by the thirty-sixth ballot he had 399 votes, enough for victory.
Garfield placated the Stalwarts by endorsing Chester A. Arthur of New York, a Conkling loyalist, as nominee for vice president, but it was to Blaine and his delegates that Garfield owed his nomination. When Garfield was elected over Democrat Winfield Scott Hancock, he turned to Blaine to guide him in selection of his cabinet and offered him the preeminent position: Secretary of State. Blaine accepted, resigning from the Senate on March 4, 1881.
James G. Blaine