In 1835 he entered the House of Commons as member for Perthshire.
In the ministry of Lord Melbourne (1835–1841), Maule was Under-Secretary of State for the Home Department, and under Lord John Russell, he was Secretary at War from July 1846 to January 1852, when for two or three weeks he was President of the Board of Control.

In April 1852, he succeeded his father as 2nd Baron Panmure.
In February 1855, he joined Lord Palmerston's cabinet, filling the new office of Secretary of State for War.
Lord Panmure held this office until February 1858.
He was at the War Office during the concluding period of the Crimean War, and met a good deal of criticism.
He was Keeper of the Privy Seal of Scotland from 1853 until his death.

Always interested in church matters, Dalhousie was a prominent supporter of the Free Church of Scotland after it split from the Church of Scotland in the disruption of 1843.
In December 1860, he succeeded his kinsman, the 1st Marquess of Dalhousie, as 11th Earl of Dalhousie.
He shortly afterwards changed his surname to "Maule-Ramsay" (his father had changed his surname to "Maule" from the family's patronymic "Ramsay" before being created Baron Panmure).
In 1835 he entered the House of Commons as member for Perthshire. In the ministry of Lord Melbourne (1835–1841), Maule was Under-Secretary of State for the Home Department, and under Lord John Russell, he was Secretary at War from July 1846 to January 1852, when for two or three weeks he was President of the Board of Control.
In April 1852, he succeeded his father as 2nd Baron Panmure. In February 1855, he joined Lord Palmerston's cabinet, filling the new office of Secretary of State for War. Lord Panmure held this office until February 1858. He was at the War Office during the concluding period of the Crimean War, and met a good deal of criticism. He was Keeper of the Privy Seal of Scotland from 1853 until his death.
Always interested in church matters, Dalhousie was a prominent supporter of the Free Church of Scotland after it split from the Church of Scotland in the disruption of 1843. In December 1860, he succeeded his kinsman, the 1st Marquess of Dalhousie, as 11th Earl of Dalhousie. He shortly afterwards changed his surname to "Maule-Ramsay" (his father had changed his surname to "Maule" from the family's patronymic "Ramsay" before being created Baron Panmure).
Fox Maule-Ramsay, 11th Earl of Dalhousie