In the fall of 2007, after three years with Zagłębie Lubin, Hertha recalled Piszczek back to the club.
He scored his first goal in the Bundesliga on 26 April 2008, to earn one point against Hannover 96.

Piszczek missed most of the first half of the 2008–09 season as the result of a hip problem that eventually required surgery.
He began training again in February 2009 but in March suffered a setback due to a minor knee injury.
He returned to Bundesliga action in April.
At Hertha, Piszczek initially played as an offensive midfielder or on left wing, but in his second season, he started to appear at right-back after an injury to Arne Friedrich.
After Friedrich recovered, Piszczek lost his place in the starting line-up, but reclaimed it in 2009–10, when Friedrich moved to centre-back.
In the fall of 2007, after three years with Zagłębie Lubin, Hertha recalled Piszczek back to the club. He scored his first goal in the Bundesliga on 26 April 2008, to earn one point against Hannover 96.
Piszczek missed most of the first half of the 2008–09 season as the result of a hip problem that eventually required surgery. He began training again in February 2009 but in March suffered a setback due to a minor knee injury. He returned to Bundesliga action in April. At Hertha, Piszczek initially played as an offensive midfielder or on left wing, but in his second season, he started to appear at right-back after an injury to Arne Friedrich. After Friedrich recovered, Piszczek lost his place in the starting line-up, but reclaimed it in 2009–10, when Friedrich moved to centre-back.
Łukasz Piszczek