In June 1840, the Manchester and Birmingham Railway (M&BR) opened a temporary terminus on its line to Stockport on Travis Street.
A large site, 1,700 ft (518 m) long by 500 ft (152 m) wide, was cleared of terraced houses and industrial premises to make way for the permanent station Store Street which was built on top of a viaduct, 30 ft (9 m) above ground level.
The station was opened adjacent to London Road on 8 May 1842.
It had two platforms, offices and passenger amenities and by then the line had been extended to Crewe.

Store Street was designed by M&BR's chief engineer, George W. Buck, who designed many of the line's structures including the Stockport Viaduct.
Charles Hutton Gregory was the assistant engineer.
The station was shared from the beginning with the Sheffield, Ashton-under-Lyne and Manchester Railway (SA&MR) following an agreement made by the promoters in 1837.

The M&BR amalgamated with other railway companies to create the London and North Western Railway (LNWR) in 1846.
The SA&MR changed its name to the Manchester, Sheffield and Lincolnshire Railway (MS&LR) three years later.
In June 1840, the Manchester and Birmingham Railway (M&BR) opened a temporary terminus on its line to Stockport on Travis Street. A large site, 1,700 ft (518 m) long by 500 ft (152 m) wide, was cleared of terraced houses and industrial premises to make way for the permanent station Store Street which was built on top of a viaduct, 30 ft (9 m) above ground level. The station was opened adjacent to London Road on 8 May 1842. It had two platforms, offices and passenger amenities and by then the line had been extended to Crewe. 
Store Street was designed by M&BR's chief engineer, George W. Buck, who designed many of the line's structures including the Stockport Viaduct. Charles Hutton Gregory was the assistant engineer. The station was shared from the beginning with the Sheffield, Ashton-under-Lyne and Manchester Railway (SA&MR) following an agreement made by the promoters in 1837.
The M&BR amalgamated with other railway companies to create the London and North Western Railway (LNWR) in 1846. The SA&MR changed its name to the Manchester, Sheffield and Lincolnshire Railway (MS&LR) three years later.
Manchester Piccadilly station