When the Berlin–Stettin railway was opened in 1842, the tracks ran farther northwestwards with a hazardous level crossing on Badstraße.
Nearby Gesundbrunnen station was inaugurated on 1 January 1872 with the northern Ringbahn line; it became an important railway hub with the opening of the Berlin Northern Railway to Neubrandenburg; the junction was finished on 10 July 1877.
From 1 May 1897, it also offered access to the Berlin–Stettin line, whose original tracks were shifted southwards to meet the parallel Ringbahn here.

On 8 August 1924 Gesundbrunnen was one of the first stations to become part of the Berlin S-Bahn system when third rail trains ran from Stettiner Bahnhof to Bernau.
After the opening of the Nord-Süd Tunnel in 1939, trains ran from Gesundbrunnen via Humboldthain station and Stettiner Bahnhof directly to Anhalter Bahnhof in the south.

Plans for an access of Gesundbrunnen station to the Berlin U-Bahn network were already developed by the AEG electric company prior to World War I. Nevertheless, the present-day station, located on the , was not opened until 18 April 1930.
Designed in a New Objectivity style according to plans by Alfred Grenander with a separate reception building, the U-Bahn platform crossed deep beneath the railway tracks and served as an air-raid shelter during the bombing of Berlin in World War II.
When the Berlin–Stettin railway was opened in 1842, the tracks ran farther northwestwards with a hazardous level crossing on Badstraße. Nearby Gesundbrunnen station was inaugurated on 1 January 1872 with the northern Ringbahn line; it became an important railway hub with the opening of the Berlin Northern Railway to Neubrandenburg; the junction was finished on 10 July 1877. From 1 May 1897, it also offered access to the Berlin–Stettin line, whose original tracks were shifted southwards to meet the parallel Ringbahn here.
On 8 August 1924 Gesundbrunnen was one of the first stations to become part of the Berlin S-Bahn system when third rail trains ran from Stettiner Bahnhof to Bernau. After the opening of the Nord-Süd Tunnel in 1939, trains ran from Gesundbrunnen via Humboldthain station and Stettiner Bahnhof directly to Anhalter Bahnhof in the south.
Plans for an access of Gesundbrunnen station to the Berlin U-Bahn network were already developed by the AEG electric company prior to World War I. Nevertheless, the present-day station, located on the , was not opened until 18 April 1930. Designed in a New Objectivity style according to plans by Alfred Grenander with a separate reception building, the U-Bahn platform crossed deep beneath the railway tracks and served as an air-raid shelter during the bombing of Berlin in World War II.
Berlin-Gesundbrunnen station