The name Almopia (Ancient Greek: Ἀλμωπία, Almōpia) derives from the Almopes (Ἀλμῶπες), a Paeonian tribe that originally inhabited the area during Antiquity.
The Almopes traced their descent to the eponymous mythological figure of Almops, son of Poseidon and Helle.
According to Thucidydes, the Almopes were expelled from the region when it was incorporated into the ancient Macedonian kingdom during the reign of Alexander I (r. 498–454 BC).
The 2nd-century astronomer and geographer Claudius Ptolemy records three cities in the region in his Geography: Horma (Ὅρμα), Europos (Εὔρωπος) and Apsalos (Ἄψαλος).

In the early Byzantine period, the area was renamed to Enotia (Greek: Ενωτία) after a nearby fortress, probably in the vicinity of modern Notia.
The name was revived between 1915 and 1927 for the Greek province as well.

In the later Middle Ages, the area was known as Moglena (Greek: Μογλενά, Macedonian: Меглен, Bulgarian: Мъглен), from the Slavic word for "fog".
Until the early 11th century, Moglena was a province of the First Bulgarian Empire.
Captured by the Byzantine emperor Basil II in 1015, it is attested as the seat of a bishopric in 1020, and as capital of its own theme in 1086.
The area remained under Byzantine rule until the aftermath of the Fourth Crusade, when it was captured by Tsar Kaloyan of the Second Bulgarian Empire.
It was incorporate in the Serbian Empire by Stefan Dušan in 1346.
Moglena was inhabited mainly by Megleno-Romanians and Slavic people.
 In Ottoman times, the region was also known by its Turkish name Karacova or Karadjova valley ("Black Valley", Greek: Καρατζόβα).

Until the Greco-Turkish War (1919–1922) and the population exchange between Greece and Turkey in 1924, Muslim Vlachs and Pomaks inhabited a large part of the regions of Moglena.
The name Almopia (Ancient Greek: Ἀλμωπία, Almōpia) derives from the Almopes (Ἀλμῶπες), a Paeonian tribe that originally inhabited the area during Antiquity. The Almopes traced their descent to the eponymous mythological figure of Almops, son of Poseidon and Helle. According to Thucidydes, the Almopes were expelled from the region when it was incorporated into the ancient Macedonian kingdom during the reign of Alexander I (r. 498–454 BC). The 2nd-century astronomer and geographer Claudius Ptolemy records three cities in the region in his Geography: Horma (Ὅρμα), Europos (Εὔρωπος) and Apsalos (Ἄψαλος).
In the early Byzantine period, the area was renamed to Enotia (Greek: Ενωτία) after a nearby fortress, probably in the vicinity of modern Notia. The name was revived between 1915 and 1927 for the Greek province as well.
In the later Middle Ages, the area was known as Moglena (Greek: Μογλενά, Macedonian: Меглен, Bulgarian: Мъглен), from the Slavic word for "fog". Until the early 11th century, Moglena was a province of the First Bulgarian Empire. Captured by the Byzantine emperor Basil II in 1015, it is attested as the seat of a bishopric in 1020, and as capital of its own theme in 1086. The area remained under Byzantine rule until the aftermath of the Fourth Crusade, when it was captured by Tsar Kaloyan of the Second Bulgarian Empire. It was incorporate in the Serbian Empire by Stefan Dušan in 1346. Moglena was inhabited mainly by Megleno-Romanians and Slavic people.  In Ottoman times, the region was also known by its Turkish name Karacova or Karadjova valley ("Black Valley", Greek: Καρατζόβα).
Until the Greco-Turkish War (1919–1922) and the population exchange between Greece and Turkey in 1924, Muslim Vlachs and Pomaks inhabited a large part of the regions of Moglena.
Almopia