Washington began playing tennis in the early 1920s around the time that her older sister, Georgia, died of tuberculosis.
In 1924, she went on to win the Wilmington, Delaware city championships in singles, doubles, and mixed doubles.
The following year, she defeated the reigning national singles champion Isadore Channels.
She won her first national title in 1925 with Lula Ballard at the American Tennis Association's national doubles tournament, which she would continue to win for the next eleven years.
After moving to Chicago in 1929, Washington won her first singles championship that same year when she defeated Frances Gittens in three sets.
She would win the title seven more times by 1937.
Despite a desire to play in United States Lawn Tennis Association tournaments, that organization maintained their policy of racial segregation until 1948, after Washington had retired from tennis.

She played basketball first in 1930 with the Germantown Hornets where her 22–1 record earned her the national female title.
The Hornets were originally sponsored by a local YMCA, but they separated from the YMCA and became a fully professional team.
The following year, Washington led the Hornets to thirty-three consecutive victories.
Their opponents included African American women's teams, white women's teams and occasionally African American men's teams.
In one game against the male Quicksteppers in January 1932, they stayed close and then on a last second basket by Evelyn Mann, the Hornets emerged victorious.

Later, playing with the Philadelphia Tribune Girls from 1932–1942, she was the team's center, leading scorer, and coach.
Washington played for the Tribunes in a three-game event against Bennett College in 1934.
The Tribunes won all three games, the second of which was described by the Chicago Defender as "the greatest exhibition ever staged in North Carolina".
The Tribune Girls won 11 straight Women's Colored Basketball World's Championships.
Washington was said to be "the best Colored player in the world."

Washington never played the top white tennis player of the time, Helen Wills Moody, because Moody refused to schedule a match.
She retired from sports in the mid-1940s, after she and partner George Stewart defeated Walter Johnson and upcoming superstar Althea Gibson to win the 1947 ATA mixed doubles title.

For the remainder of her life, she supported herself as a housekeeper.
She died in 1971 in Germantown and was buried in her Virginia hometown.
Washington began playing tennis in the early 1920s around the time that her older sister, Georgia, died of tuberculosis. In 1924, she went on to win the Wilmington, Delaware city championships in singles, doubles, and mixed doubles. The following year, she defeated the reigning national singles champion Isadore Channels. She won her first national title in 1925 with Lula Ballard at the American Tennis Association's national doubles tournament, which she would continue to win for the next eleven years. After moving to Chicago in 1929, Washington won her first singles championship that same year when she defeated Frances Gittens in three sets. She would win the title seven more times by 1937. Despite a desire to play in United States Lawn Tennis Association tournaments, that organization maintained their policy of racial segregation until 1948, after Washington had retired from tennis.
She played basketball first in 1930 with the Germantown Hornets where her 22–1 record earned her the national female title. The Hornets were originally sponsored by a local YMCA, but they separated from the YMCA and became a fully professional team. The following year, Washington led the Hornets to thirty-three consecutive victories. Their opponents included African American women's teams, white women's teams and occasionally African American men's teams. In one game against the male Quicksteppers in January 1932, they stayed close and then on a last second basket by Evelyn Mann, the Hornets emerged victorious.
Later, playing with the Philadelphia Tribune Girls from 1932–1942, she was the team's center, leading scorer, and coach. Washington played for the Tribunes in a three-game event against Bennett College in 1934. The Tribunes won all three games, the second of which was described by the Chicago Defender as "the greatest exhibition ever staged in North Carolina". The Tribune Girls won 11 straight Women's Colored Basketball World's Championships. Washington was said to be "the best Colored player in the world."
Washington never played the top white tennis player of the time, Helen Wills Moody, because Moody refused to schedule a match. She retired from sports in the mid-1940s, after she and partner George Stewart defeated Walter Johnson and upcoming superstar Althea Gibson to win the 1947 ATA mixed doubles title.
For the remainder of her life, she supported herself as a housekeeper. She died in 1971 in Germantown and was buried in her Virginia hometown.
Ora Washington