Mystikal headlined a concert at the Mahalia Jackson Theater of the Performing Arts on Mardi Gras, February 16, 2010.
Mystikal's first song after being released from prison was an underground track with former No Limit labelmate Fiend entitled "I Don't Like You".
A few weeks later, Atlanta-based, New Orleans-born R&B artist Lloyd released "Set Me Free" featuring Mystikal.
The music video for "Set Me Free" was released on May 18, 2010 and was shot in New Orleans, primarily from the Calliope Projects.

In an interview in May 2010, he stated that he was still obligated to Jive Records for one more album and would be taking the necessary time to ensure the album would be his best to date.
He made a promo song called "Papercuts" featuring Fiend and Lil Wayne.
In 2011, he performed at the Gathering of the Juggalos.
Mystikal and Busta Rhymes were signed to Cash Money Records by Birdman on November 16 the same year.
His first single for the label, "Original", was released shortly thereafter and featured new label-mates Birdman and Lil Wayne.

In 2014, Mystikal recorded "Feel Right" for Mark Ronson's Uptown Special.
The song and video were released in 2015.

Also in 2015, Mystikal appeared on Stevie Stone's Single Rain Dance with Tech N9ne from the 2015 release Malta Bend.

In January 2016, he performed in shows in Bahrain and Bulgaria with Danny!
In February 2016, Mystikal toured the United States.

In April 2016, Mystikal was featured on Just a Lil' Thick (She Juicy) by Trinidad James along with Lil Dicky.
Mystikal headlined a concert at the Mahalia Jackson Theater of the Performing Arts on Mardi Gras, February 16, 2010. Mystikal's first song after being released from prison was an underground track with former No Limit labelmate Fiend entitled "I Don't Like You". A few weeks later, Atlanta-based, New Orleans-born R&B artist Lloyd released "Set Me Free" featuring Mystikal. The music video for "Set Me Free" was released on May 18, 2010 and was shot in New Orleans, primarily from the Calliope Projects.
In an interview in May 2010, he stated that he was still obligated to Jive Records for one more album and would be taking the necessary time to ensure the album would be his best to date. He made a promo song called "Papercuts" featuring Fiend and Lil Wayne. In 2011, he performed at the Gathering of the Juggalos. Mystikal and Busta Rhymes were signed to Cash Money Records by Birdman on November 16 the same year. His first single for the label, "Original", was released shortly thereafter and featured new label-mates Birdman and Lil Wayne.
In 2014, Mystikal recorded "Feel Right" for Mark Ronson's Uptown Special. The song and video were released in 2015.
Also in 2015, Mystikal appeared on Stevie Stone's Single Rain Dance with Tech N9ne from the 2015 release Malta Bend.
In January 2016, he performed in shows in Bahrain and Bulgaria with Danny! In February 2016, Mystikal toured the United States.
In April 2016, Mystikal was featured on Just a Lil' Thick (She Juicy) by Trinidad James along with Lil Dicky.
Mystikal