Prêles is first mentioned in 1179 as Prales though this document is believed to be a 12th-century forgery.
 In 1185 it was mentioned as Preles and it used to be known by its German name Prägelz.

Beginning in the 12th century the noble de Perls family first appears in records.
 The family existed for several centuries before vanishing from records in the 15th century.
 Throughout its history the village was part of the Herrschaft of Tessenberg (Diesse).
 The major landowners in the village included the collegiate church of Saint-Imier and Erlach Abbey.
 It was part of the parish of Diesse and accepted the Protestant Reformation along with the rest of the parish between 1530 and 1554.

After the 1798 French invasion, Prêles became part of the French Département of Mont-Terrible.
 Three years later, in 1800 it became part of the Département of Haut-Rhin.
 After Napoleon's defeat and the Congress of Vienna, Prêles was assigned to the Canton of Bern in 1815.
 Initially it was part of the District of Erlach but in 1846 it became part of the La Neuveville District.

The construction of a cable railway between Ligerz and Prêles in 1912 turned it into a minor tourist destination.
 Until the 1950s agriculture was the most important industry in the village.
 Today many residents commute to jobs in Biel or La Neuveville.
 In the past decades a number of new houses were built for the growing commuter population.
Prêles is first mentioned in 1179 as Prales though this document is believed to be a 12th-century forgery.  In 1185 it was mentioned as Preles and it used to be known by its German name Prägelz.
Beginning in the 12th century the noble de Perls family first appears in records.  The family existed for several centuries before vanishing from records in the 15th century.  Throughout its history the village was part of the Herrschaft of Tessenberg (Diesse).  The major landowners in the village included the collegiate church of Saint-Imier and Erlach Abbey.  It was part of the parish of Diesse and accepted the Protestant Reformation along with the rest of the parish between 1530 and 1554.
After the 1798 French invasion, Prêles became part of the French Département of Mont-Terrible.  Three years later, in 1800 it became part of the Département of Haut-Rhin.  After Napoleon's defeat and the Congress of Vienna, Prêles was assigned to the Canton of Bern in 1815.  Initially it was part of the District of Erlach but in 1846 it became part of the La Neuveville District.
The construction of a cable railway between Ligerz and Prêles in 1912 turned it into a minor tourist destination.  Until the 1950s agriculture was the most important industry in the village.  Today many residents commute to jobs in Biel or La Neuveville.  In the past decades a number of new houses were built for the growing commuter population.
Plateau de Diesse