Plaquemine Historic District is a historic district in downtown Plaquemine, Louisiana, located along Railroad Avenue, Main Street, Eden Street, Church Street, Plaquemine Street and Court Street.

The 55-acre (22 ha) area comprises a total of 133 buildings and structures, of which 95 are considered contributing properties, and 3 are also listed on the National Register of Historic Places as individual properties.
Building dates vary from c.1840 to c.1938 and are mostly historic brick commercial buildings and residences of either brick or frame construction.

The historic district was listed on the National Register of Historic Places on October 30, 1989.

Boundaries were increased on June 3 2005, with the addition of the house at 57725 Court Street, the nearby Carriage House/Stable and Blacksmith Shop.
Plaquemine Historic District is a historic district in downtown Plaquemine, Louisiana, located along Railroad Avenue, Main Street, Eden Street, Church Street, Plaquemine Street and Court Street.
The 55-acre (22 ha) area comprises a total of 133 buildings and structures, of which 95 are considered contributing properties, and 3 are also listed on the National Register of Historic Places as individual properties. Building dates vary from c.1840 to c.1938 and are mostly historic brick commercial buildings and residences of either brick or frame construction.
The historic district was listed on the National Register of Historic Places on October 30, 1989.
Boundaries were increased on June 3 2005, with the addition of the house at 57725 Court Street, the nearby Carriage House/Stable and Blacksmith Shop.
Plaquemine Historic District