After the decline of Bahmanid Sultanate, the city fell to Nizam Shahi rulers of Ahmadnagar.
Several wars were fought in Beed between Nizam Shahi and Adil Shahigfug rulers of Bijapur to take the control of Beed.
In 1598 Mughals captured Beed from Chand Bibi of Ahmadnagar.
A year later Nihang Khan retook it but soon it fell again to Mughals.
Mughal army camped here for some time.
During the reign of Jahangir (1569–1627), Jan Sipar Khan was administering Beed city.
He constructed Jama Masjid of Beed in 1036 AH (1627).

Aurangzeb (1658–1707), appointed Haji Sadar Shah in Beed as Naib-e-Subadar (assistant of governor).
Sadar Shah did some good changes and constructions in the city.
He built Eid Gah (place of Eid prayer) in 1702 and a new habitation on the heights in the eastern part as Ghazi Pura (now Islam Pura) in 1703.
The remains of it are still visible.
 He also constructed a citadel (1703) inside the old fort which was worn out after standing for several hundred years, from Tughluq period.
A stone plate in Persian script at the main entry of Jama Masjid sets the year of construction of citadel by Haji Sadar Shah in the year 1115 AH (1703).
In his period economy of the city also flourished.
Chhagal (water container made from leather), Gupti (hidden sword in wooden stick) etc.
made in Beed were popular in the region.

Beed was quite a beautiful city during Bahmanids and Mughals.
Tārīkh-e-Bīr mentions many gardens and amenities of these periods.
Until the 1960s there were two well maintained gardens in the city.

In 1724 Nizam-ul-Mulk Asaf Jah founded Asaf Jahi kingdom, seizing Deccan against the rule of Mughal emperor Muhammad Shah (1719–48).
In Nizams' era no major addition or construction was done to the citadel because the old building was serving the purpose and the citadels were losing importance with the advent of modern fighting techniques.

Maratha ruler of Gwalior, Mahadji Scindia (1761–94) was missing after a severe injury and defeat in the third war of Panipat in 1761.
His wife, who is said to be from Beed, went to a Muslim Sufi of Beed Mansur Shah and told him to prey for the return of Mahadji.
When Mahadji returned to Gwalior, he called the Sufi to Gwalior but he refused and sent his son Habib Shah instead.
Mahadji remained thankful to Mansur Shah for all his life.
His tomb is in eastern Beed which was built by Scindias.

Reign of sixth Nizam Mir Mahbub Ali Khan (1869–1911) proved eventful in the history of Beed.
Rebels, great famine and floods happened in his reign.
Jagirdars were replaced by collectors (Awwal Taluqdars) in his father's reign and Jivanji Ratanji came as the first collector of Beed in 1865.
Districts were created and Beed district was formally settled in 1883.
He constructed one habitation and market Mahbub Gunj (now Hiralal Chowk) on the eastern bank of Bensura, remains of that can still be seen.
After a very scarce rainfall in three successive years 1897–99, great famine occurred in Beed in 1900.
Thousands of cattle and Hundreds of humans died of starvation and thousands migrated to the neighbouring parts of the country.
The census in 1901 reported remarkable decrease of 150,464 in the population of Beed district.
Mir Osman Ali Khan (1911–48) came after death of Mahbub Ali Khan as seventh and the last Nizam of Hyderabad State.
His period was full of reforms in the government system, education and healthcare.
Kotwalis, Police Stations, Schools, Hospitals and Dispensaries were built during his period.
He established big libraries with the high schools in the state.

Nizams were allies of the British Empire in India.
During the countrywide movement for independence, in 19th and 20th centuries they tried to suppress the feelings of nationalism which were spreading due to nationwide efforts of the freedom fighters.
Nationalists in the state of Hyderabad did not like Nizam's friendship with the British Empire.
Beed was the place in Marathwada region where freedom struggle first started in 1818.

In 1818 during the rule of Nizam Sikandar Jah (1803–29) first rebel broke out in Beed under the leadership of
After the decline of Bahmanid Sultanate, the city fell to Nizam Shahi rulers of Ahmadnagar. Several wars were fought in Beed between Nizam Shahi and Adil Shahigfug rulers of Bijapur to take the control of Beed. In 1598 Mughals captured Beed from Chand Bibi of Ahmadnagar. A year later Nihang Khan retook it but soon it fell again to Mughals. Mughal army camped here for some time. During the reign of Jahangir (1569–1627), Jan Sipar Khan was administering Beed city. He constructed Jama Masjid of Beed in 1036 AH (1627).
Aurangzeb (1658–1707), appointed Haji Sadar Shah in Beed as Naib-e-Subadar (assistant of governor). Sadar Shah did some good changes and constructions in the city. He built Eid Gah (place of Eid prayer) in 1702 and a new habitation on the heights in the eastern part as Ghazi Pura (now Islam Pura) in 1703. The remains of it are still visible.  He also constructed a citadel (1703) inside the old fort which was worn out after standing for several hundred years, from Tughluq period. A stone plate in Persian script at the main entry of Jama Masjid sets the year of construction of citadel by Haji Sadar Shah in the year 1115 AH (1703). In his period economy of the city also flourished. Chhagal (water container made from leather), Gupti (hidden sword in wooden stick) etc. made in Beed were popular in the region.
Beed was quite a beautiful city during Bahmanids and Mughals. Tārīkh-e-Bīr mentions many gardens and amenities of these periods. Until the 1960s there were two well maintained gardens in the city.
In 1724 Nizam-ul-Mulk Asaf Jah founded Asaf Jahi kingdom, seizing Deccan against the rule of Mughal emperor Muhammad Shah (1719–48). In Nizams' era no major addition or construction was done to the citadel because the old building was serving the purpose and the citadels were losing importance with the advent of modern fighting techniques.
Maratha ruler of Gwalior, Mahadji Scindia (1761–94) was missing after a severe injury and defeat in the third war of Panipat in 1761. His wife, who is said to be from Beed, went to a Muslim Sufi of Beed Mansur Shah and told him to prey for the return of Mahadji. When Mahadji returned to Gwalior, he called the Sufi to Gwalior but he refused and sent his son Habib Shah instead. Mahadji remained thankful to Mansur Shah for all his life. His tomb is in eastern Beed which was built by Scindias.
Reign of sixth Nizam Mir Mahbub Ali Khan (1869–1911) proved eventful in the history of Beed. Rebels, great famine and floods happened in his reign. Jagirdars were replaced by collectors (Awwal Taluqdars) in his father's reign and Jivanji Ratanji came as the first collector of Beed in 1865. Districts were created and Beed district was formally settled in 1883. He constructed one habitation and market Mahbub Gunj (now Hiralal Chowk) on the eastern bank of Bensura, remains of that can still be seen. After a very scarce rainfall in three successive years 1897–99, great famine occurred in Beed in 1900. Thousands of cattle and Hundreds of humans died of starvation and thousands migrated to the neighbouring parts of the country. The census in 1901 reported remarkable decrease of 150,464 in the population of Beed district. Mir Osman Ali Khan (1911–48) came after death of Mahbub Ali Khan as seventh and the last Nizam of Hyderabad State. His period was full of reforms in the government system, education and healthcare. Kotwalis, Police Stations, Schools, Hospitals and Dispensaries were built during his period. He established big libraries with the high schools in the state.
Nizams were allies of the British Empire in India. During the countrywide movement for independence, in 19th and 20th centuries they tried to suppress the feelings of nationalism which were spreading due to nationwide efforts of the freedom fighters. Nationalists in the state of Hyderabad did not like Nizam's friendship with the British Empire. Beed was the place in Marathwada region where freedom struggle first started in 1818.
In 1818 during the rule of Nizam Sikandar Jah (1803–29) first rebel broke out in Beed under the leadership of
Beed