When the Jinghan Railway from Beijing reached Hankou in the early 20th century, its terminus was the Hankou Dazhimen station (大智门火车站), located right outside the walls of the bustling port city of Hankou.
In 1991 the Dazhimen station was closed, and services were relocated to the present Hankou railway station, located several kilometers north of central Hankou.

Hankou railway station became connected to Wuhan Metro on December 28, 2012, with the opening of Line 2 of the city's subway system.

The station's location near the Huanan Seafood Wholesale Market may have contributed to the spread of the Coronavirus disease 2019.
On 23 January 2020, the station was closed, along with  all other transport infrastructure in the city, due to the outbreak of Coronavirus disease 2019.
This unprecedented measure in human history became known as the 2020 Wuhan lockdown.
On 28 March, the station resumed operation for arrivals only; full operation was resumed on 5 April.
When the Jinghan Railway from Beijing reached Hankou in the early 20th century, its terminus was the Hankou Dazhimen station (大智门火车站), located right outside the walls of the bustling port city of Hankou. In 1991 the Dazhimen station was closed, and services were relocated to the present Hankou railway station, located several kilometers north of central Hankou.
Hankou railway station became connected to Wuhan Metro on December 28, 2012, with the opening of Line 2 of the city's subway system.
The station's location near the Huanan Seafood Wholesale Market may have contributed to the spread of the Coronavirus disease 2019. On 23 January 2020, the station was closed, along with  all other transport infrastructure in the city, due to the outbreak of Coronavirus disease 2019. This unprecedented measure in human history became known as the 2020 Wuhan lockdown. On 28 March, the station resumed operation for arrivals only; full operation was resumed on 5 April.
Hankou railway station