Born in Kirkcaldy, she grew up in the town of Buckhaven, Fife.
Mitchell went on to become the only girl to play for her local high school team at the age of twelve.
She started her career with St Johnstone Girls, alongside fellow future Frauen-Bundesliga player Lisa Evans, before both girls joined Scottish Women's Premier League champions Glasgow City in August 2008.

At the end of the 2012 season, Mitchell had a trial period in Denmark with earlier Champions League opponents Fortuna Hjørring, before heading for further trials in Sweden and Germany.

Mitchell signed professionally for Frauen-Bundesliga side SGS Essen in January 2013.
After just four months, reports in Germany linked Mitchell with a transfer to English champions Arsenal.
Arsenal confirmed the move on 22 July 2013.

Whilst at Arsenal, Mitchell won an FA Cup in 2014 with WSL Cups coming in 2013 and 2015.
With the Gunners, she also went on a successful run to the FA Cup final of 2016.
Arsenal beat Chelsea 1–0 at Wembley and Mitchell lifted the 2016 FA Cup.

On 3 January 2020, it was announced that Mitchell would be joining Tottenham Hotspur on loan for the rest of the season.
Born in Kirkcaldy, she grew up in the town of Buckhaven, Fife. Mitchell went on to become the only girl to play for her local high school team at the age of twelve. She started her career with St Johnstone Girls, alongside fellow future Frauen-Bundesliga player Lisa Evans, before both girls joined Scottish Women's Premier League champions Glasgow City in August 2008.
At the end of the 2012 season, Mitchell had a trial period in Denmark with earlier Champions League opponents Fortuna Hjørring, before heading for further trials in Sweden and Germany.
Mitchell signed professionally for Frauen-Bundesliga side SGS Essen in January 2013. After just four months, reports in Germany linked Mitchell with a transfer to English champions Arsenal. Arsenal confirmed the move on 22 July 2013.
Whilst at Arsenal, Mitchell won an FA Cup in 2014 with WSL Cups coming in 2013 and 2015. With the Gunners, she also went on a successful run to the FA Cup final of 2016. Arsenal beat Chelsea 1–0 at Wembley and Mitchell lifted the 2016 FA Cup.
On 3 January 2020, it was announced that Mitchell would be joining Tottenham Hotspur on loan for the rest of the season.
Emma Mitchell