The forces of King Edward I of England invaded Scotland at the start of the war, and seized Bothwell, also capturing Walter's son, William Moray of Bothwell.
The English garrison holding the castle was besieged by the Scots for 14 months in 1298—1299, and eventually capitulated.
Edward I returned in 1301, capturing the castle once more with a force of 6800 men, and specially constructed siege engines.
Bothwell became the headquarters of Aymer de Valence, 2nd Earl of Pembroke, Edward's appointed Warden of Scotland, and remained in English hands for several years.

Following Robert the Bruce's victory at Bannockburn in 1314, the castle provided shelter for several English nobles.
However, the castle's constable, Sir Walter FitzGilbert, surrendered the castle to the approaching Scots.
For this act, he was granted the barony of Cadzow, where his descendants became the powerful Hamilton family.
The Scots slighted the castle after its surrender.

In 1336 the English returned again, this time under Edward III.
The English king had the castle repaired, and again made it his headquarters in Scotland.
The following year, however, Sir Andrew Murray, nephew of Sir William and the rightful owner of Bothwell, recaptured the stronghold, again using siege engines.
Following his victory he slighted the castle once more, pulling down the west side of the donjon and tumbling it into the Clyde, in order that it could not be reoccupied by the enemy.
The castle remained derelict until the 1360s.
The forces of King Edward I of England invaded Scotland at the start of the war, and seized Bothwell, also capturing Walter's son, William Moray of Bothwell. The English garrison holding the castle was besieged by the Scots for 14 months in 1298—1299, and eventually capitulated. Edward I returned in 1301, capturing the castle once more with a force of 6800 men, and specially constructed siege engines. Bothwell became the headquarters of Aymer de Valence, 2nd Earl of Pembroke, Edward's appointed Warden of Scotland, and remained in English hands for several years.
Following Robert the Bruce's victory at Bannockburn in 1314, the castle provided shelter for several English nobles. However, the castle's constable, Sir Walter FitzGilbert, surrendered the castle to the approaching Scots. For this act, he was granted the barony of Cadzow, where his descendants became the powerful Hamilton family. The Scots slighted the castle after its surrender.
In 1336 the English returned again, this time under Edward III. The English king had the castle repaired, and again made it his headquarters in Scotland. The following year, however, Sir Andrew Murray, nephew of Sir William and the rightful owner of Bothwell, recaptured the stronghold, again using siege engines. Following his victory he slighted the castle once more, pulling down the west side of the donjon and tumbling it into the Clyde, in order that it could not be reoccupied by the enemy. The castle remained derelict until the 1360s.
Bothwell Castle