He formed the center-left party Desiya Murpokku Dravida Kazhagam (DMDK), a regional political party in Tamil Nadu.
He formally announced the party's formation on 14 September 2005 in Madurai.
His party contested in all seats in 2006 assembly elections and won one seat contested by him.

The DMDK, led by Vijaykanth, proved to be an important player in the 2006 Tamil Nadu assembly election, garnering 10% of the voters and securing 10.1% in this Lok Sabha election.
According to the study, it secured more votes than the winning margins of candidates in about 25 constituencies.
In 2006, polling showed that DMDK was able to get more DMK votes than AIADMK votes, but in this election, they were able to wrestle more Congress voters from 2004 than any other party.
Contrary to the claim of many in the AIADMK camp blaming DMDK for the defeat, there is no evidence for this to be true.
Vijayakanth has declared that he would not ask donations for his party, and most of the funding for the party comes from his own pocket.
He has so far rejected alliances with other political parties.
In a by-election to Madurai Central assembly constituency, DMDK secured around 17000 votes, which is just 2000 votes less than AIADMK.
DMDK was also able to secure a significant number of seats in Local Body elections.
He formed the center-left party Desiya Murpokku Dravida Kazhagam (DMDK), a regional political party in Tamil Nadu. He formally announced the party's formation on 14 September 2005 in Madurai. His party contested in all seats in 2006 assembly elections and won one seat contested by him.
The DMDK, led by Vijaykanth, proved to be an important player in the 2006 Tamil Nadu assembly election, garnering 10% of the voters and securing 10.1% in this Lok Sabha election. According to the study, it secured more votes than the winning margins of candidates in about 25 constituencies. In 2006, polling showed that DMDK was able to get more DMK votes than AIADMK votes, but in this election, they were able to wrestle more Congress voters from 2004 than any other party. Contrary to the claim of many in the AIADMK camp blaming DMDK for the defeat, there is no evidence for this to be true. Vijayakanth has declared that he would not ask donations for his party, and most of the funding for the party comes from his own pocket. He has so far rejected alliances with other political parties. In a by-election to Madurai Central assembly constituency, DMDK secured around 17000 votes, which is just 2000 votes less than AIADMK. DMDK was also able to secure a significant number of seats in Local Body elections.
Vijayakanth