At its western terminus, SR 10 is the eastward extension of Andrew Young International Boulevard NE and Ellis Street NE and has an interchange with I-75/I-85 (Downtown Connector) on the eastern edge of Downtown Atlanta, in Fulton County.
At Jackson Street NE, the highway enters Freedom Park and becomes known as Freedom Parkway.
A block later, it curves to the northeast and has an incomplete interchange with the southern terminus of SR 42 Connector, which acts like an eastern spur of Freedom Parkway.
After that, SR 10 begins to curve to the north and passes to the west of the Jimmy Carter Library and Museum and the Carter Center; then, it curves to the north-northwest and has an intersection with US 29/US 78/US 278/SR 8 (Ponce de Leon Avenue NE).
The five highways travel concurrently to the east and exit the park.
They pass the Briarcliff Plaza shopping center and intersect North Highland Avenue NE, before meeting US 23/SR 42 (Moreland Avenue NE/Briarcliff Road NE) on the Fulton–DeKalb county line.
At this intersection, US 23 joins the concurrency.
The six highways pass by Springdale Park, Springdale Park Elementary School, Virgilee Park, The Paideia School, St. John's Lutheran Church, Brightwood Park, Shady Side Park, and the Lullwater Estate, before intersecting Clifton Road on the southeastern corner of the Druid Hills Golf Club.
Just past this intersection, the concurrency passes by Dellwood Park, enters Druid Hills, and passes the Fernbank Museum of Natural History.
After that, they cross over Lullwater Creek.
On the southern edge of Deepdene Park, US 278/SR 10 depart the concurrency to the southeast on East Lake Drive NE.
As soon as they enter Decatur, they curve to the south-southeast and travel underneath Howard Avenue and College Avenue.
They turn right onto Park Place NE, and follow it to the west and north for about three blocks; then, they turn right onto College Avenue and travel along it to the east-northeast.
US 278/SR 10 pass by Renfroe Middle School, Raiders Park, Decatur High School, and Agnes Scott College, before intersecting SR 155 (South Candler Street) and the southern terminus of East Trinity Place.
SR 155 joins the concurrency for about three blocks and departs on Commerce Drive.
A short distance later, the two highways leave Decatur and pass the Avondale MARTA station; then, they enter Avondale Estates, where they pass Avondale Elementary School.
At Mountain Drive, SR 10 departs from US 278 to the northeast.
This intersection marks the western terminus of SR 12.
The short Mountain Drive segment of SR 10 pass north of the Kinsington MARTA station.
At the eastern terminus of Mountain Drive is an intersection with the eastern terminus of SR 154 (Memorial Drive).
At this intersection, SR 10 turns left onto Memorial Drive and passes the DeKalb County Sheriff's Headquarters and Jail.
About one block later, SR 10 has an interchange with I-285 (Atlanta Bypass).
Northeast of Rockbridge Road, the highway passes Georgia Piedmont Technical College, Georgia Perimeter College, Clarkston High School, and James R. Hallford Stadium.
It curves to the east and crosses Snapfinger Creek.
SR 10 skirts along the northwestern edge of Stone Mountain and has an interchange with East Ponce de Leon Avenue, just before meeting US 78/SR 410 (Stone Mountain Freeway).
At this interchange, SR 410 meets its eastern terminus, and US 78/SR 10 travel concurrently.
Within the interchange, the roadway curves to the east-northeast.
Almost immediately after the interchange, the freeway passes under the Silver Hill Road overpass and begins to skirt along the northwestern edge of Stone Mountain Park.
A short distance later, they cross over Stone Mountain Creek, travel just to the north of the Stone Mountain Park Dam–North Dam and Stone Mountain Park Lake–North, and have an interchange with the southern terminus of SR 236 (Hugh Howell Road).
Here, the roadway enters Stone Mountain Park proper.
The freeway crosses over Little Stone Mountain Creek before the westbound and eastbound lanes diverge from each other.
The eastbound lanes curve to
At its western terminus, SR 10 is the eastward extension of Andrew Young International Boulevard NE and Ellis Street NE and has an interchange with I-75/I-85 (Downtown Connector) on the eastern edge of Downtown Atlanta, in Fulton County. At Jackson Street NE, the highway enters Freedom Park and becomes known as Freedom Parkway. A block later, it curves to the northeast and has an incomplete interchange with the southern terminus of SR 42 Connector, which acts like an eastern spur of Freedom Parkway. After that, SR 10 begins to curve to the north and passes to the west of the Jimmy Carter Library and Museum and the Carter Center; then, it curves to the north-northwest and has an intersection with US 29/US 78/US 278/SR 8 (Ponce de Leon Avenue NE). The five highways travel concurrently to the east and exit the park. They pass the Briarcliff Plaza shopping center and intersect North Highland Avenue NE, before meeting US 23/SR 42 (Moreland Avenue NE/Briarcliff Road NE) on the Fulton–DeKalb county line. At this intersection, US 23 joins the concurrency. The six highways pass by Springdale Park, Springdale Park Elementary School, Virgilee Park, The Paideia School, St. John's Lutheran Church, Brightwood Park, Shady Side Park, and the Lullwater Estate, before intersecting Clifton Road on the southeastern corner of the Druid Hills Golf Club. Just past this intersection, the concurrency passes by Dellwood Park, enters Druid Hills, and passes the Fernbank Museum of Natural History. After that, they cross over Lullwater Creek. On the southern edge of Deepdene Park, US 278/SR 10 depart the concurrency to the southeast on East Lake Drive NE. As soon as they enter Decatur, they curve to the south-southeast and travel underneath Howard Avenue and College Avenue. They turn right onto Park Place NE, and follow it to the west and north for about three blocks; then, they turn right onto College Avenue and travel along it to the east-northeast. US 278/SR 10 pass by Renfroe Middle School, Raiders Park, Decatur High School, and Agnes Scott College, before intersecting SR 155 (South Candler Street) and the southern terminus of East Trinity Place. SR 155 joins the concurrency for about three blocks and departs on Commerce Drive. A short distance later, the two highways leave Decatur and pass the Avondale MARTA station; then, they enter Avondale Estates, where they pass Avondale Elementary School. At Mountain Drive, SR 10 departs from US 278 to the northeast. This intersection marks the western terminus of SR 12. The short Mountain Drive segment of SR 10 pass north of the Kinsington MARTA station. At the eastern terminus of Mountain Drive is an intersection with the eastern terminus of SR 154 (Memorial Drive). At this intersection, SR 10 turns left onto Memorial Drive and passes the DeKalb County Sheriff's Headquarters and Jail. About one block later, SR 10 has an interchange with I-285 (Atlanta Bypass). Northeast of Rockbridge Road, the highway passes Georgia Piedmont Technical College, Georgia Perimeter College, Clarkston High School, and James R. Hallford Stadium. It curves to the east and crosses Snapfinger Creek. SR 10 skirts along the northwestern edge of Stone Mountain and has an interchange with East Ponce de Leon Avenue, just before meeting US 78/SR 410 (Stone Mountain Freeway). At this interchange, SR 410 meets its eastern terminus, and US 78/SR 10 travel concurrently. Within the interchange, the roadway curves to the east-northeast. Almost immediately after the interchange, the freeway passes under the Silver Hill Road overpass and begins to skirt along the northwestern edge of Stone Mountain Park. A short distance later, they cross over Stone Mountain Creek, travel just to the north of the Stone Mountain Park Dam–North Dam and Stone Mountain Park Lake–North, and have an interchange with the southern terminus of SR 236 (Hugh Howell Road). Here, the roadway enters Stone Mountain Park proper. The freeway crosses over Little Stone Mountain Creek before the westbound and eastbound lanes diverge from each other. The eastbound lanes curve to 
Georgia State Route 10