Semple has supported Amnesty International and has created artworks for the Freedom of Expression Campaign. "
There are more artists living in East London than in the whole of Renaissance Italy and we're doing all sorts of weird and wonderful things every day," he pointed out, "but there are other people all over the world who don't have the privilege of being able to say what they think."
He also spoke for Amnesty about positive mental health being a Human Right alongside Joe Pantoliano and Colm O'Gorman during Ireland's "First Fortnight" arts festival.

In 2010 Semple spoke for the first time about how his life changed after a near death experience a decade earlier. "
Up until that day I was a normal kid, I went to art school, I was like everyone else ... Then I had this awful week when I had a huge allergic reaction, my tongue swelled up so big I could hardly breathe and I found myself in a hospital bed, dying."

2011 Semple was made an Ambassador for mental health charity Mind.
He initiated the Creative Therapies fund within the organisation which he launched with Stephen Fry and Melvyn Bragg and curated the exhibition & auction "Mindful" that included works from Jake & Dinos Chapman, Mat Collishaw, Tracey Emin, Mona Hatoum, Sarah Lucas and Sebastian Horsley.

Semple recently created a whole body of work and short film for a solo booth at London's ART13 with all proceeds in aid of the Mind Creative Therapies fund  For Mind's Time To Change campaign he designed a series of well wishing e-cards and temporary tattoos
"My Happy Place" was a citywide exhibition in Coventry that coincided with 2015 World Mental Health Day and saw live events, film, food, art and sculpture initiated and created by Semple with Coventry's The Pod collective.
Semple's Happy Place consisted of a Unicorn shaped spinning disco mirror ball.

The Creative Therapies fund has backed projects nationwide since 2012 and has stepped in to save some groups where local government funding had been cut.
Semple talks about his understanding in a Mind interview "…Often those suffering find it hard to express their feelings with words, but being creative in a proper therapeutic environment with trained therapists is a very powerful path to healing.
The results are phenomenal I meet and hear from so many people who literally tell me creative therapy has changed their lives so I'm on a real mission to help people understand that and to spread it as far as I can".

Semple was vocal about the Arts Cuts imposed following the recession making an artwork "The First Cut" which was exhibited in Hong Kong as part of "The British Cut" exhibition, showcasing major contemporary artists latest work and pictured the scene from the demonstration.
His 2010 exhibition "Happy House" opened on the eve of the General Election and the opening was broadcast live on the BBC with the works addressing fears of a future where creativity is overlooked.
Semple spoke in The Guardian "I believe that society and its institutions should be doing much more to encourage young people to follow their dreams – helping them to avoid a future of missed opportunity and regret" and in The Huffington Post "The creative industries are a massive contributing factor to our economy and across all those fields we desperately need new dreamers."
Semple has appeared on BBC art shows mentoring students, talking about his techniques and inviting them to visit his studio.

Semple met with Vince Cable to discuss the impact on artists lives with proposed changes to Artists Resale Right so lower priced sales still counted as it make a difference to younger artists, also for the royalty to pass to their children, saying "The art world should be trying to support and nurture subsequent generations of talent."
He spoke to the Student Handbook about this "The creative industries count towards a huge proportion of our economy, it's something like 16% which is nearly as much as banking.
It's short-sighted of the government to put these cuts in place because as a country we are extremely creative, whether it's advertising, graphic
Semple has supported Amnesty International and has created artworks for the Freedom of Expression Campaign. "There are more artists living in East London than in the whole of Renaissance Italy and we're doing all sorts of weird and wonderful things every day," he pointed out, "but there are other people all over the world who don't have the privilege of being able to say what they think." He also spoke for Amnesty about positive mental health being a Human Right alongside Joe Pantoliano and Colm O'Gorman during Ireland's "First Fortnight" arts festival.
In 2010 Semple spoke for the first time about how his life changed after a near death experience a decade earlier. "Up until that day I was a normal kid, I went to art school, I was like everyone else ... Then I had this awful week when I had a huge allergic reaction, my tongue swelled up so big I could hardly breathe and I found myself in a hospital bed, dying."
2011 Semple was made an Ambassador for mental health charity Mind. He initiated the Creative Therapies fund within the organisation which he launched with Stephen Fry and Melvyn Bragg and curated the exhibition & auction "Mindful" that included works from Jake & Dinos Chapman, Mat Collishaw, Tracey Emin, Mona Hatoum, Sarah Lucas and Sebastian Horsley.
Semple recently created a whole body of work and short film for a solo booth at London's ART13 with all proceeds in aid of the Mind Creative Therapies fund  For Mind's Time To Change campaign he designed a series of well wishing e-cards and temporary tattoos
"My Happy Place" was a citywide exhibition in Coventry that coincided with 2015 World Mental Health Day and saw live events, film, food, art and sculpture initiated and created by Semple with Coventry's The Pod collective. Semple's Happy Place consisted of a Unicorn shaped spinning disco mirror ball.
The Creative Therapies fund has backed projects nationwide since 2012 and has stepped in to save some groups where local government funding had been cut. Semple talks about his understanding in a Mind interview "…Often those suffering find it hard to express their feelings with words, but being creative in a proper therapeutic environment with trained therapists is a very powerful path to healing. The results are phenomenal I meet and hear from so many people who literally tell me creative therapy has changed their lives so I'm on a real mission to help people understand that and to spread it as far as I can".
Semple was vocal about the Arts Cuts imposed following the recession making an artwork "The First Cut" which was exhibited in Hong Kong as part of "The British Cut" exhibition, showcasing major contemporary artists latest work and pictured the scene from the demonstration. His 2010 exhibition "Happy House" opened on the eve of the General Election and the opening was broadcast live on the BBC with the works addressing fears of a future where creativity is overlooked. Semple spoke in The Guardian "I believe that society and its institutions should be doing much more to encourage young people to follow their dreams – helping them to avoid a future of missed opportunity and regret" and in The Huffington Post "The creative industries are a massive contributing factor to our economy and across all those fields we desperately need new dreamers." Semple has appeared on BBC art shows mentoring students, talking about his techniques and inviting them to visit his studio.
Semple met with Vince Cable to discuss the impact on artists lives with proposed changes to Artists Resale Right so lower priced sales still counted as it make a difference to younger artists, also for the royalty to pass to their children, saying "The art world should be trying to support and nurture subsequent generations of talent." He spoke to the Student Handbook about this "The creative industries count towards a huge proportion of our economy, it's something like 16% which is nearly as much as banking. It's short-sighted of the government to put these cuts in place because as a country we are extremely creative, whether it's advertising, graphic
Stuart Semple