Around 1534, Ralph Sadler married Ellen, daughter of John Mitchell, of Much Hadham, Hertfordshire, who at the time of their marriage was believed to be the widow of Matthew Barre (or Barrow) of Sevenoaks in Kent.
The couple had three sons and four daughters:
Thomas Sadler of Standon, Hertfordshire, (c. 1536 – 1607), named after Thomas Cromwell, who succeeded him married twice:
Ursula, daughter of John Sherington of Lacock, Wiltshire
Gertrude, daughter of Robert Markham, of Cotham, Nottinghamshire,  by whom he had  a son Ralph, and a  daughter Gertrude, who married Walter Aston, 1st Lord Aston of Forfar
Edward Sadler of Temple Dinsley, (died 4 April 1584) married Anne, daughter and heir of Sir Richard Lee of Sopwell, Hertfordshire
Henry Sadler of Everleigh, Wiltshire, (c. 1538 – 1618), married twice:
Mary, daughter of Gilbert Everley
Ursula, daughter of John Gill
Anne Sadler (died 1576), married George Horsey of Digswell, Hertfordshire
Mary Sadler married Thomas Bolle of Wallington, Hertfordshire
Jane Sadler (died c. 1587), married Edward Bash of Stanstedbury, Hertfordshire
Dorothy Sadler (died c. 1578), married Edward Elrington of Byrchall, Essex
Sadler may have had an illegitimate son, Richard.
Around 1534, Ralph Sadler married Ellen, daughter of John Mitchell, of Much Hadham, Hertfordshire, who at the time of their marriage was believed to be the widow of Matthew Barre (or Barrow) of Sevenoaks in Kent. The couple had three sons and four daughters:
Thomas Sadler of Standon, Hertfordshire, (c. 1536 – 1607), named after Thomas Cromwell, who succeeded him married twice:
Ursula, daughter of John Sherington of Lacock, Wiltshire
Gertrude, daughter of Robert Markham, of Cotham, Nottinghamshire,  by whom he had  a son Ralph, and a  daughter Gertrude, who married Walter Aston, 1st Lord Aston of Forfar
Edward Sadler of Temple Dinsley, (died 4 April 1584) married Anne, daughter and heir of Sir Richard Lee of Sopwell, Hertfordshire
Henry Sadler of Everleigh, Wiltshire, (c. 1538 – 1618), married twice:
Mary, daughter of Gilbert Everley
Ursula, daughter of John Gill
Anne Sadler (died 1576), married George Horsey of Digswell, Hertfordshire
Mary Sadler married Thomas Bolle of Wallington, Hertfordshire
Jane Sadler (died c. 1587), married Edward Bash of Stanstedbury, Hertfordshire
Dorothy Sadler (died c. 1578), married Edward Elrington of Byrchall, Essex
Sadler may have had an illegitimate son, Richard.
Ralph Sadler