Study of the matrix protein VP40 is important due to the high mortality rate of the Ebola virus, which is listed as a WHO Risk Group 4 Pathogen, an HHS Select Agent, an NIH/NIAID Category A Priority Pathogen, a CDC Category A Bioterrorism Agent, and a Biological Agent for Export Control by the Australia Group.

Expression of the matrix protein VP40 is sufficient to generate virus-like particles (no viral genetic material) in a mammalian host that are remarkably indistinguishable from live virus, from a morphological standpoint.
Study of the matrix protein VP40 is important due to the high mortality rate of the Ebola virus, which is listed as a WHO Risk Group 4 Pathogen, an HHS Select Agent, an NIH/NIAID Category A Priority Pathogen, a CDC Category A Bioterrorism Agent, and a Biological Agent for Export Control by the Australia Group.
Expression of the matrix protein VP40 is sufficient to generate virus-like particles (no viral genetic material) in a mammalian host that are remarkably indistinguishable from live virus, from a morphological standpoint.
VP40