Following the Treaty of Campo Formio, where Napoleon Bonaparte decreed the final dissolution of the Venetian Republic, Preveza – like other Venetian possessions in Greece and Albania – was ceded to Revolutionary France.
280 French grenadiers arrived in Preveza under the commands of General La Salchette.
The people of Preveza welcomed the French troops, and formed a pro-French civic militia.
Around this same time the poet Rigas Feraios was combining support for the ideas of the French Revolution with calls for a Greek uprising against Ottoman rule.
He was intercepted and killed by the Ottoman authorities when en route to meet Napoleon and directly ask for his help for the Greek cause.

Napoleon Bonaparte, however, focused his attention in another direction, launching the French Campaign in Egypt and Syria, placing France at war with the Ottoman Empire and giving little thought to the fate of the small Preveza garrison exposed on the edge of Ottoman territory.
In October 1798, the local Ottoman governor Ali Pasha Tepelena – having great ambitions to make himself a semi-independent ruler – attacked Preveza with an overwhelming force.
In the Battle of Nicopolis on 12 October 1798 the 7,000 Ottoman troops of Ali Pasha and his son Mukhtar completely overwhelmed the 280 French grenadiers and their local allies, the 200 Preveza Civil Guards and 60 Souliote warriors under Captain Christakis.
Over the next two days, 13–14 October 1798, a major massacre of the French troops and the local Greek population which defended the city took place in Preveza and Port Salaora, on the Ambracian Gulf, starting before Ali Pasha entered Preveza on 13 October but also continuing in his presence.
On 14 October, Ali Pasha called on those citizens of Preveza who had escaped to the Acarnanian Mountains to return to the city, and declared that they would be in no danger.
However, upon their return, 170 of them were executed by the sword at the Salaora Port Customs.
Many prisoners who survived the massacre died from the hardships on the road to Ioannina.
In the grand return and reception held for his victorious troops, which Ali Pasha organized at Ioannina, surviving French and rebel prisoners were given the unpleasant role of walking at the head of the procession, holding the cut and salted heads of their companions, under the shouts and jeers of Ioannina's pro-Ottoman residents.
From Ioannina, nine captured French grenadiers, and two officers were sent chained to Istanbul for questioning.
One of them, Captain Louis-Auguste Camus de Richemont, was later released, possibly mediated by the mother of Napoleon Bonaparte, Maria Letizia Bonaparte, and eventually became a general.
Some popularly circulating tales, of doubtful historical authenticity, link this incident with the origins of the Spoonmaker's Diamond, one of the most closely guarded treasures of Istanbul's Topkapı Palace.

Though Preveza would remain under Ottoman rule for more than a century, this event – both the short period of Greek militias active in the city and the shock of the massacre that followed – and the influence of the ideas of the French Revolution had a part in the development of Greek nationalism towards the Greek War of Independence, which broke out three decades later.
Following the Treaty of Campo Formio, where Napoleon Bonaparte decreed the final dissolution of the Venetian Republic, Preveza – like other Venetian possessions in Greece and Albania – was ceded to Revolutionary France. 280 French grenadiers arrived in Preveza under the commands of General La Salchette. The people of Preveza welcomed the French troops, and formed a pro-French civic militia. Around this same time the poet Rigas Feraios was combining support for the ideas of the French Revolution with calls for a Greek uprising against Ottoman rule. He was intercepted and killed by the Ottoman authorities when en route to meet Napoleon and directly ask for his help for the Greek cause.
Napoleon Bonaparte, however, focused his attention in another direction, launching the French Campaign in Egypt and Syria, placing France at war with the Ottoman Empire and giving little thought to the fate of the small Preveza garrison exposed on the edge of Ottoman territory. In October 1798, the local Ottoman governor Ali Pasha Tepelena – having great ambitions to make himself a semi-independent ruler – attacked Preveza with an overwhelming force. In the Battle of Nicopolis on 12 October 1798 the 7,000 Ottoman troops of Ali Pasha and his son Mukhtar completely overwhelmed the 280 French grenadiers and their local allies, the 200 Preveza Civil Guards and 60 Souliote warriors under Captain Christakis. Over the next two days, 13–14 October 1798, a major massacre of the French troops and the local Greek population which defended the city took place in Preveza and Port Salaora, on the Ambracian Gulf, starting before Ali Pasha entered Preveza on 13 October but also continuing in his presence. On 14 October, Ali Pasha called on those citizens of Preveza who had escaped to the Acarnanian Mountains to return to the city, and declared that they would be in no danger. However, upon their return, 170 of them were executed by the sword at the Salaora Port Customs. Many prisoners who survived the massacre died from the hardships on the road to Ioannina. In the grand return and reception held for his victorious troops, which Ali Pasha organized at Ioannina, surviving French and rebel prisoners were given the unpleasant role of walking at the head of the procession, holding the cut and salted heads of their companions, under the shouts and jeers of Ioannina's pro-Ottoman residents. From Ioannina, nine captured French grenadiers, and two officers were sent chained to Istanbul for questioning. One of them, Captain Louis-Auguste Camus de Richemont, was later released, possibly mediated by the mother of Napoleon Bonaparte, Maria Letizia Bonaparte, and eventually became a general. Some popularly circulating tales, of doubtful historical authenticity, link this incident with the origins of the Spoonmaker's Diamond, one of the most closely guarded treasures of Istanbul's Topkapı Palace.
Though Preveza would remain under Ottoman rule for more than a century, this event – both the short period of Greek militias active in the city and the shock of the massacre that followed – and the influence of the ideas of the French Revolution had a part in the development of Greek nationalism towards the Greek War of Independence, which broke out three decades later.
Preveza