At Bonaparte's invitation he joined the expedition to Egypt as part of the arts and literature section of the Institut d'Égypte, and thus found the opportunity of gathering the materials for his most important literary and artistic work.
He accompanied General Desaix to Upper Egypt, and made numerous sketches of the monuments of ancient art, sometimes under the very fire of the enemy.
The results were published in his Voyage dans la basse et la haute Egypte (Journey in Lower and Upper Egypt), published as two volumes in 1802.
 The work crowned his reputation both as an archaeologist and as an artist, and sparked the Egyptian Revival in architecture and decorative arts. (
See: Egyptian Revival architecture and Egyptian revival decorative arts)
On 19 November 1802, he was appointed by Napoleon to the important office of director-general of museums and head of the new Musée Napoléon, which he filled until the Allied occupation of Paris in 1814, when he had to retire.
He was a devoted servant of Napoleon, on whose behalf he personally looted vast numbers of works of art in Italy, the Low Countries and Germany and, through agents (including Goya), in Spain, for the Musee Napoleon in Paris.
Many of these remain in the Louvre, and elsewhere in France, today.
In particular, Denon was one of the very first men to appreciate the importance of the Italian 'primitives'.
The majority of those now in the Louvre were looted by Denon during a sweep he made through Italy in 1812.
They were publicly paraded, with elephants 
and other wild animals, like a Roman triumph, through the streets of Paris, before being deposited in the Louvre.

Denon took full opportunity, while working for Napoleon, to assemble for himself an enormous collection of paintings, drawings, prints, books, statuary and objets d'art.
This collection was sold at auction over several days after Denon's death.
In 1810 he also assisted the Hermitage Museum in its acquisition of Rosso Fiorentino's Madonna and Child with Cherubs in Paris.
At Bonaparte's invitation he joined the expedition to Egypt as part of the arts and literature section of the Institut d'Égypte, and thus found the opportunity of gathering the materials for his most important literary and artistic work. He accompanied General Desaix to Upper Egypt, and made numerous sketches of the monuments of ancient art, sometimes under the very fire of the enemy. The results were published in his Voyage dans la basse et la haute Egypte (Journey in Lower and Upper Egypt), published as two volumes in 1802.  The work crowned his reputation both as an archaeologist and as an artist, and sparked the Egyptian Revival in architecture and decorative arts. (See: Egyptian Revival architecture and Egyptian revival decorative arts)
On 19 November 1802, he was appointed by Napoleon to the important office of director-general of museums and head of the new Musée Napoléon, which he filled until the Allied occupation of Paris in 1814, when he had to retire. He was a devoted servant of Napoleon, on whose behalf he personally looted vast numbers of works of art in Italy, the Low Countries and Germany and, through agents (including Goya), in Spain, for the Musee Napoleon in Paris. Many of these remain in the Louvre, and elsewhere in France, today. In particular, Denon was one of the very first men to appreciate the importance of the Italian 'primitives'. The majority of those now in the Louvre were looted by Denon during a sweep he made through Italy in 1812. They were publicly paraded, with elephants 
and other wild animals, like a Roman triumph, through the streets of Paris, before being deposited in the Louvre.
Denon took full opportunity, while working for Napoleon, to assemble for himself an enormous collection of paintings, drawings, prints, books, statuary and objets d'art. This collection was sold at auction over several days after Denon's death. In 1810 he also assisted the Hermitage Museum in its acquisition of Rosso Fiorentino's Madonna and Child with Cherubs in Paris.
Vivant Denon