Kroh married twice.
His first wife was Sophie Susanne Købke (3 May 1807 - 15 July 1853), a daughter of master baker at Kastellet Peter Berendt Købke and Cecilia Margrethe Petersen.
Her brother was the painter Christen Købke.
They were married on 3 May 1835 and had four children  Pietro Købke Krohn (1840–1905), Johan Jacob Krohn (1841–1925), Herman Freund Krohn (1843–1877) and Mario Krohn (1846–1872).
They later also adopted Christen Købke's two children, Hans Peter Carl Købke and Juliane Emilie Købke, who lost their father in 1848 and their mother in 1849.

Krohn was second time married to Emilie Købke (17 July 1812 - 1 January 1880 ) a daughter of kancelliråd Caspar Berendt Købke and Juliane Dorothea Ratz, on On 31 July, 1855 in Vester Åby Church onb Funen.

Krohn died on 13 September 1883 at Copenhagen Municipal Hospital.
He is buried in Assistens Cemetery.
Kroh married twice. His first wife was Sophie Susanne Købke (3 May 1807 - 15 July 1853), a daughter of master baker at Kastellet Peter Berendt Købke and Cecilia Margrethe Petersen. Her brother was the painter Christen Købke. They were married on 3 May 1835 and had four children  Pietro Købke Krohn (1840–1905), Johan Jacob Krohn (1841–1925), Herman Freund Krohn (1843–1877) and Mario Krohn (1846–1872). They later also adopted Christen Købke's two children, Hans Peter Carl Købke and Juliane Emilie Købke, who lost their father in 1848 and their mother in 1849.
Krohn was second time married to Emilie Købke (17 July 1812 - 1 January 1880 ) a daughter of kancelliråd Caspar Berendt Købke and Juliane Dorothea Ratz, on On 31 July, 1855 in Vester Åby Church onb Funen.
Krohn died on 13 September 1883 at Copenhagen Municipal Hospital. He is buried in Assistens Cemetery.
Frederik Christopher Krohn