Medvedev made his ATP main draw debut at the 2015 Kremlin Cup, partnering Aslan Karatsev in the doubles event.

As a qualifier, Medvedev made his ATP singles main draw debut at the 2016 Nice Open, losing to Guido Pella in three sets.
Three weeks later he earned his first singles ATP World Tour win at the 2016 Ricoh Open, defeating Horacio Zeballos in straight sets.

Medvedev was disqualified from the second round of the Savannah Challenger event (in Georgia, U.S.) for comments he made after the umpire ruled in favor of his opponent.
Medvedev thought he had won a break point against his opponent Donald Young's serve, but chair umpire Sandy French ruled that his returning shot had gone out.
Medvedev said Young and French, who are both African-Americans, were friends.
He was disqualified mid-match for allegedly 'question[ing] the impartiality of the umpire based on her race'.
Medvedev made his ATP main draw debut at the 2015 Kremlin Cup, partnering Aslan Karatsev in the doubles event.
As a qualifier, Medvedev made his ATP singles main draw debut at the 2016 Nice Open, losing to Guido Pella in three sets. Three weeks later he earned his first singles ATP World Tour win at the 2016 Ricoh Open, defeating Horacio Zeballos in straight sets.
Medvedev was disqualified from the second round of the Savannah Challenger event (in Georgia, U.S.) for comments he made after the umpire ruled in favor of his opponent. Medvedev thought he had won a break point against his opponent Donald Young's serve, but chair umpire Sandy French ruled that his returning shot had gone out. Medvedev said Young and French, who are both African-Americans, were friends. He was disqualified mid-match for allegedly 'question[ing] the impartiality of the umpire based on her race'.
Daniil Medvedev