Cylindropuntia bigelovii grows in desert regions at elevations to about 3,000 ft (900 m) in the "Low Desert" or Colorado Desert of Southern California, and in other Sonoran Desert regions of the Southwestern United States and northwestern Mexico.

In the Lower Colorado River Valley, the most dense Cylindropuntia bigelovii stands are at higher elevations, in the rockiest sites.
There are fewer Sonoran Desert or Colorado Desert plant association species, but two are common though reduced in size: ocotillo (Fouquieria splendens) and saguaro (Carnegiea gigantea).

The teddy bear cholla is also found in a protected Cholla Cactus Garden as part of the Joshua Tree National Park among other desert plants such as the desert senna, pencil cholla, creosote bush, jojoba, and climbing milkweed Sarcostemma cynanxhoides ssp.
hartweggi which can climb and cover the teddy bear cholla and may even kill it.
Cylindropuntia bigelovii grows in desert regions at elevations to about 3,000 ft (900 m) in the "Low Desert" or Colorado Desert of Southern California, and in other Sonoran Desert regions of the Southwestern United States and northwestern Mexico.
In the Lower Colorado River Valley, the most dense Cylindropuntia bigelovii stands are at higher elevations, in the rockiest sites. There are fewer Sonoran Desert or Colorado Desert plant association species, but two are common though reduced in size: ocotillo (Fouquieria splendens) and saguaro (Carnegiea gigantea).
The teddy bear cholla is also found in a protected Cholla Cactus Garden as part of the Joshua Tree National Park among other desert plants such as the desert senna, pencil cholla, creosote bush, jojoba, and climbing milkweed Sarcostemma cynanxhoides ssp. hartweggi which can climb and cover the teddy bear cholla and may even kill it.
Cylindropuntia bigelovii