He was born to an Ulster Scots family in County Antrim in what is now Northern Ireland, and emigrated with his widowed mother to Indiana when he was nine years old.
 He grew up in near poverty on a farm and graduated from Valparaiso High School in 1875.
He worked his way through Knox College, where he co-founded its student newspaper, and later moved to New York City.

In 1884, he established the McClure Syndicate, the first U.S. newspaper syndicate, and published in Sunday newspapers, containing serials of books, recipes and reviews.

He founded McClure's Magazine in 1893 and ran it successfully until 1911 when poor health and financial reorganization forced him out (and many of his writers had defected to form their own magazine).
McClure's Magazine published influential pieces by respected journalists and authors including Jack London, Ida Tarbell, Upton Sinclair, Burton J. Hendrick, Rudyard Kipling, Sir Arthur Conan Doyle, Robert Louis Stevenson, Willa Cather, and Lincoln Steffens.
Through his magazine, he introduced Dr. Maria Montessori's new teaching methods to North America in 1911.

McClure was a business partner of Frank Nelson Doubleday in Doubleday & McClure, ancestor to today's Doubleday imprint.
After McClure left Doubleday, he established the publisher McClure, Phillips and Company with John Sanborn Phillips.
Phillips left to purchase The American Magazine in 1906 and McClure sold his book publishing operations to Doubleday, Page in 1908.
After he was ousted in 1911, McClure's Magazine serialized his autobiography, ghost-written by one of the magazine's editors, Willa Cather.

McClure created a whole new form of writing for his journalists that we still use today.
Instead of demanding that his writers give him articles for his paper immediately, he would give them all the time they needed to do extensive research on their topics.

Rudyard Kipling was one writer who rejected McClure's offer of a long term contract, quoting as justification Ecclesiasticus (Chapt.
33, verse 21): "As long as thou livest and hast breath in thee, give not thyself over to any".
Kipling was also present when McClure began to contemplate the launch of a new literary magazine.
He recalled in his autobiography:
He entered [my home in Vermont], alight with the notion for a new Magazine to be called 'McClure's.'
I think the talk lasted some twelve—or it may have been seventeen—hours, before the notion was fully hatched out.

He died in New York City in 1949, at the age of 92.
He is buried next to his wife Harriet at Hope Cemetery in Galesburg, Illinois.
He was born to an Ulster Scots family in County Antrim in what is now Northern Ireland, and emigrated with his widowed mother to Indiana when he was nine years old.  He grew up in near poverty on a farm and graduated from Valparaiso High School in 1875. He worked his way through Knox College, where he co-founded its student newspaper, and later moved to New York City.
In 1884, he established the McClure Syndicate, the first U.S. newspaper syndicate, and published in Sunday newspapers, containing serials of books, recipes and reviews.
He founded McClure's Magazine in 1893 and ran it successfully until 1911 when poor health and financial reorganization forced him out (and many of his writers had defected to form their own magazine). McClure's Magazine published influential pieces by respected journalists and authors including Jack London, Ida Tarbell, Upton Sinclair, Burton J. Hendrick, Rudyard Kipling, Sir Arthur Conan Doyle, Robert Louis Stevenson, Willa Cather, and Lincoln Steffens. Through his magazine, he introduced Dr. Maria Montessori's new teaching methods to North America in 1911.
McClure was a business partner of Frank Nelson Doubleday in Doubleday & McClure, ancestor to today's Doubleday imprint. After McClure left Doubleday, he established the publisher McClure, Phillips and Company with John Sanborn Phillips. Phillips left to purchase The American Magazine in 1906 and McClure sold his book publishing operations to Doubleday, Page in 1908. After he was ousted in 1911, McClure's Magazine serialized his autobiography, ghost-written by one of the magazine's editors, Willa Cather.
McClure created a whole new form of writing for his journalists that we still use today. Instead of demanding that his writers give him articles for his paper immediately, he would give them all the time they needed to do extensive research on their topics.
Rudyard Kipling was one writer who rejected McClure's offer of a long term contract, quoting as justification Ecclesiasticus (Chapt. 33, verse 21): "As long as thou livest and hast breath in thee, give not thyself over to any". Kipling was also present when McClure began to contemplate the launch of a new literary magazine. He recalled in his autobiography:
He entered [my home in Vermont], alight with the notion for a new Magazine to be called 'McClure's.' I think the talk lasted some twelve—or it may have been seventeen—hours, before the notion was fully hatched out.
He died in New York City in 1949, at the age of 92. He is buried next to his wife Harriet at Hope Cemetery in Galesburg, Illinois.
S. S. McClure