The river is formed near the community of Rock Cave in southwestern Upshur County by the confluence of small headwaters tributaries known as Straight Fork and Whites Camp Fork.
 From this confluence the West Fork River flows north through Lewis, Harrison and Marion counties, through the communities of Weston, West Milford, Clarksburg, Lumberport, Shinnston, Enterprise, Worthington, and Monongah to Fairmont, where it joins the Tygart Valley River from the west to form the Monongahela River. (
The Tygart is thus the "East Fork" of the Monongahela.)
Among other tributaries, it collects Stonecoal Creek in Weston; Hackers Creek in southern Harrison County; Elk Creek in Clarksburg; and Simpson Creek and Tenmile Creek in northern Harrison County.

The West Fork has a low gradient and is slow-moving throughout its course.
 It is locally popular for fishing, and is stocked with muskellunge by the West Virginia Division of Natural Resources.
 Other fish species in the river include carp; channel and flathead catfish; golden and rainbow trout; largemouth, smallmouth, and spotted bass; sauger; and walleye.

Jackson's Mill was established along the river north of Weston around the year 1800 by Edward Jackson; his grandson, Thomas "Stonewall" Jackson lived there during much of his youth.
 The site has been operated as a 4-H facility since the 1920s.

A walking trail parallels the river for 1.2 miles (2 km) in Veteran's Park in Clarksburg.
 For much of its length between Clarksburg and Fairmont, the West Fork is paralleled by a pair of rail trails on the route of a mid-19th century line of the Baltimore and Ohio Railroad.
 The Harrison County Trail extends northward from Clarksburg, and the West Fork River Trail connects Shinnston to Fairmont.
 A long-term closure of the connection between the two trails is anticipated, due to the presence of hazardous waste at an industrial site near the community of Spelter in northern Harrison County.
The river is formed near the community of Rock Cave in southwestern Upshur County by the confluence of small headwaters tributaries known as Straight Fork and Whites Camp Fork.  From this confluence the West Fork River flows north through Lewis, Harrison and Marion counties, through the communities of Weston, West Milford, Clarksburg, Lumberport, Shinnston, Enterprise, Worthington, and Monongah to Fairmont, where it joins the Tygart Valley River from the west to form the Monongahela River. (The Tygart is thus the "East Fork" of the Monongahela.) Among other tributaries, it collects Stonecoal Creek in Weston; Hackers Creek in southern Harrison County; Elk Creek in Clarksburg; and Simpson Creek and Tenmile Creek in northern Harrison County.
The West Fork has a low gradient and is slow-moving throughout its course.  It is locally popular for fishing, and is stocked with muskellunge by the West Virginia Division of Natural Resources.  Other fish species in the river include carp; channel and flathead catfish; golden and rainbow trout; largemouth, smallmouth, and spotted bass; sauger; and walleye.
Jackson's Mill was established along the river north of Weston around the year 1800 by Edward Jackson; his grandson, Thomas "Stonewall" Jackson lived there during much of his youth.  The site has been operated as a 4-H facility since the 1920s.
A walking trail parallels the river for 1.2 miles (2 km) in Veteran's Park in Clarksburg.  For much of its length between Clarksburg and Fairmont, the West Fork is paralleled by a pair of rail trails on the route of a mid-19th century line of the Baltimore and Ohio Railroad.  The Harrison County Trail extends northward from Clarksburg, and the West Fork River Trail connects Shinnston to Fairmont.  A long-term closure of the connection between the two trails is anticipated, due to the presence of hazardous waste at an industrial site near the community of Spelter in northern Harrison County.
West Fork River