In 1875, the station became the site of a state telegraph office.
In 1887, a curve was opened connecting the line from Schifferstadt towards the line to Neustadt (Maximilian Railway); this meant that freight trains from the east no longer had to reverse in the station.
The station received ticket gates on 15 October 1906.

The station, together with the rest of the Palatinate rail network, became part of the Palatine Ludwig Railway Company (Pfälzische Ludwigsbahn-Gesellschaft) on 1 January 1909.
From 16 December 1912 onwards, the so-called Palatine Overland Railway (Pfälzer Oberlandbahn)  ran from the station forecourt as an interurban, first as far as Edenkoben and from 13 January 1913 to Landau.
Its purpose was to link several places between Neustadt and Landau, which had not been connected to the Maximilian Railway.
At the beginning of the First World War, a total of 401 trains passed through the station from 2 to 18 August.
40 trains ran from Mannheim daily; 20 of them continued to Saarbrücken, the remaining ones ran on to the Maximilian Railway in Neustadt.
After Germany had lost the war and the French military had marched in, the Maximilian Railway south of Maikammer-Kirrweiler was blockaded for passenger traffic on 1 December 1918, but it was reopened three days later.

The station was integrated into the newly founded Reichsbahndirektion Ludwigshafen (railway division of Ludwigshafen).
During the dissolution of the railway division of Ludwigshafen on 1 April 1937, it was transferred to the railway division of Mainz.

In the two world wars the station was hardly affected.
After the Second World War, it became part of the Bundesbahndirektion Mainz (Deutsche Bundesbahn division of Mainz), which had succeeded the Reichsbahndirektion Mainz.
In the 1950s, the Palatine Overland Railway was shut down.
The railway station was redesigned and modernised in 1960.
In 1875, the station became the site of a state telegraph office. In 1887, a curve was opened connecting the line from Schifferstadt towards the line to Neustadt (Maximilian Railway); this meant that freight trains from the east no longer had to reverse in the station. The station received ticket gates on 15 October 1906.
The station, together with the rest of the Palatinate rail network, became part of the Palatine Ludwig Railway Company (Pfälzische Ludwigsbahn-Gesellschaft) on 1 January 1909. From 16 December 1912 onwards, the so-called Palatine Overland Railway (Pfälzer Oberlandbahn)  ran from the station forecourt as an interurban, first as far as Edenkoben and from 13 January 1913 to Landau. Its purpose was to link several places between Neustadt and Landau, which had not been connected to the Maximilian Railway. At the beginning of the First World War, a total of 401 trains passed through the station from 2 to 18 August. 40 trains ran from Mannheim daily; 20 of them continued to Saarbrücken, the remaining ones ran on to the Maximilian Railway in Neustadt. After Germany had lost the war and the French military had marched in, the Maximilian Railway south of Maikammer-Kirrweiler was blockaded for passenger traffic on 1 December 1918, but it was reopened three days later.
The station was integrated into the newly founded Reichsbahndirektion Ludwigshafen (railway division of Ludwigshafen). During the dissolution of the railway division of Ludwigshafen on 1 April 1937, it was transferred to the railway division of Mainz.
In the two world wars the station was hardly affected. After the Second World War, it became part of the Bundesbahndirektion Mainz (Deutsche Bundesbahn division of Mainz), which had succeeded the Reichsbahndirektion Mainz. In the 1950s, the Palatine Overland Railway was shut down. The railway station was redesigned and modernised in 1960.
Neustadt (Weinstraße) Hauptbahnhof