Traditional interpretation holds that the Descent of the Holy Spirit took place in the Upper Room, or Cenacle, on the day of Pentecost (Shavuot).
The Upper Room was first mentioned in Luke 22:12–13.
This Upper Room was to be the location of the Last Supper and the institution of Holy Communion.
The other mention of an "upper room" is in Acts 1:13–14, the continuation of the Luke narrative, authored by the same biblical writer.

Here the disciples and women waited and they gave themselves up to constant prayer, until the arrival of the "wind" mentioned above.
Traditional interpretation holds that the Descent of the Holy Spirit took place in the Upper Room, or Cenacle, on the day of Pentecost (Shavuot). The Upper Room was first mentioned in Luke 22:12–13. This Upper Room was to be the location of the Last Supper and the institution of Holy Communion. The other mention of an "upper room" is in Acts 1:13–14, the continuation of the Luke narrative, authored by the same biblical writer.
Here the disciples and women waited and they gave themselves up to constant prayer, until the arrival of the "wind" mentioned above.
Acts 2