Independence was originally inhabited by Missouri and Osage Indians, followed by the Spanish and a brief French tenure.
 It became part of the United States with the Louisiana Purchase in 1803.
 Lewis and Clark recorded in their journals that they stopped in 1804 to pick plums, raspberries, and wild apples at a site that would later form part of the city.
Independence was also a stopping point for the "Donner Party", an ill fated group of 19th Century wagon train emigrants whose westward journey along the California Trail ended in disaster; spawning one of the most well known and taboo stories of pioneer era America.

Named after the Declaration of Independence, Independence was founded on March 29, 1827, and quickly became an important frontier town.
Independence was the farthest point westward on the Missouri River where the steamboats or other cargo vessels could travel, due to the convergence of the Kansas River with the Missouri River approximately six miles west of town, near the current Kansas-Missouri border.
Independence immediately became a jumping-off point for the emerging fur trade, accommodating merchants and adventurers beginning the long trek westward on the Santa Fe Trail.

In 1831, members of the Latter Day Saint movement began moving to the Jackson County, Missouri area.
 Shortly thereafter, founder Joseph Smith declared a spot west of the Courthouse Square to be the place for his prophesied temple of the New Jerusalem, in expectation of the Second Coming of Christ.
 Tension grew with local Missourians until the Latter Day Saints were driven from the area in 1833, the beginning of a conflict which culminated in the 1838 Mormon War.
 Several branches of this movement gradually returned to the city beginning in 1867, with many making their headquarters there.
 These include the Community of Christ (formerly the Reorganized Church of Jesus Christ of Latter Day Saints), the Church of Christ (Temple Lot), the Church of Jesus Christ (Cutlerite) and the Restoration Branches.

Independence saw great prosperity from the late 1830s through the mid-1840s, while the business of outfitting pioneers boomed.
 Between 1848 and 1868, it was a hub of the California Trail.
 On March 8, 1849, the Missouri General Assembly granted a home-rule charter to the town and on July 18, 1849, William McCoy was elected as its first mayor.
 In the mid-19th century an Act of the United States Congress defined Independence as the start of the Oregon Trail.

Independence saw two important battles during the Civil War: the first on August 11, 1862, when Confederate soldiers took control of the town, and the second in October 1864, which also resulted in a Southern victory.
 The war took its toll on Independence and the town was never able to regain its previous prosperity, although a flurry of building activity took place soon after the war.
 The rise of nearby Kansas City also contributed to the town's relegation to a place of secondary prominence in Jackson County, though Independence has retained its position as county seat to the present day.

United States President Harry S. Truman grew up in Independence, and in 1922 was elected judge of the county Court of Jackson County, Missouri (an administrative, not judicial, post).
 Although he was defeated for reelection in 1924, he won back the office in 1926 and was reelected in 1930.
 Truman performed his duties diligently, and won personal acclaim for several popular public works projects, including an extensive series of fine roads for the growing use of automobiles, the building of a new County Court building in Independence, and a series of 12 Madonna of the Trail monuments to pioneer women dedicated across the country in 1928 and 1929.
 He would later return to the city after two terms as president.
 His wife, First Lady Bess Truman, was born and raised in Independence, and both are buried there.
 The Harry S. Truman National Historic Site (Truman's home) and the Harry S. Truman Presidential Library and Museum are both located in Independence, as is one of Truman's boyhood residences.
Independence was originally inhabited by Missouri and Osage Indians, followed by the Spanish and a brief French tenure.  It became part of the United States with the Louisiana Purchase in 1803.  Lewis and Clark recorded in their journals that they stopped in 1804 to pick plums, raspberries, and wild apples at a site that would later form part of the city. Independence was also a stopping point for the "Donner Party", an ill fated group of 19th Century wagon train emigrants whose westward journey along the California Trail ended in disaster; spawning one of the most well known and taboo stories of pioneer era America. 
Named after the Declaration of Independence, Independence was founded on March 29, 1827, and quickly became an important frontier town. Independence was the farthest point westward on the Missouri River where the steamboats or other cargo vessels could travel, due to the convergence of the Kansas River with the Missouri River approximately six miles west of town, near the current Kansas-Missouri border. Independence immediately became a jumping-off point for the emerging fur trade, accommodating merchants and adventurers beginning the long trek westward on the Santa Fe Trail.
In 1831, members of the Latter Day Saint movement began moving to the Jackson County, Missouri area.  Shortly thereafter, founder Joseph Smith declared a spot west of the Courthouse Square to be the place for his prophesied temple of the New Jerusalem, in expectation of the Second Coming of Christ.  Tension grew with local Missourians until the Latter Day Saints were driven from the area in 1833, the beginning of a conflict which culminated in the 1838 Mormon War.  Several branches of this movement gradually returned to the city beginning in 1867, with many making their headquarters there.  These include the Community of Christ (formerly the Reorganized Church of Jesus Christ of Latter Day Saints), the Church of Christ (Temple Lot), the Church of Jesus Christ (Cutlerite) and the Restoration Branches.
Independence saw great prosperity from the late 1830s through the mid-1840s, while the business of outfitting pioneers boomed.  Between 1848 and 1868, it was a hub of the California Trail.  On March 8, 1849, the Missouri General Assembly granted a home-rule charter to the town and on July 18, 1849, William McCoy was elected as its first mayor.  In the mid-19th century an Act of the United States Congress defined Independence as the start of the Oregon Trail.
Independence saw two important battles during the Civil War: the first on August 11, 1862, when Confederate soldiers took control of the town, and the second in October 1864, which also resulted in a Southern victory.  The war took its toll on Independence and the town was never able to regain its previous prosperity, although a flurry of building activity took place soon after the war.  The rise of nearby Kansas City also contributed to the town's relegation to a place of secondary prominence in Jackson County, though Independence has retained its position as county seat to the present day.
United States President Harry S. Truman grew up in Independence, and in 1922 was elected judge of the county Court of Jackson County, Missouri (an administrative, not judicial, post).  Although he was defeated for reelection in 1924, he won back the office in 1926 and was reelected in 1930.  Truman performed his duties diligently, and won personal acclaim for several popular public works projects, including an extensive series of fine roads for the growing use of automobiles, the building of a new County Court building in Independence, and a series of 12 Madonna of the Trail monuments to pioneer women dedicated across the country in 1928 and 1929.  He would later return to the city after two terms as president.  His wife, First Lady Bess Truman, was born and raised in Independence, and both are buried there.  The Harry S. Truman National Historic Site (Truman's home) and the Harry S. Truman Presidential Library and Museum are both located in Independence, as is one of Truman's boyhood residences.
Independence, Missouri