Wilton began her career on stage in 1969 at the Nottingham Playhouse.
Her early roles included Cordelia in King Lear, both in Nottingham and at The Old Vic.

She made her Broadway debut in March 1971 when she played Araminta in the original Broadway production of The Philanthropist, and made her West End debut in August 1971 opposite Sir Ralph Richardson, in the John Osborne play West of Suez at the Cambridge Theatre.
She had previously appeared in both plays at the Royal Court Theatre.
She played Ruth in the original 1974 London stage production of Alan Ayckbourn's Norman Conquests trilogy.

Her television acting career began in 1972, playing Vivie Warren in the BBC2's adaptation of Mrs. Warren's Profession opposite Coral Browne in the title role and Robert Powell.
The production was repeated as part of the Play of the Month series in 1974 on BBC1.
In 1994, Wilton portrayed Browne in a radio adaptation of An Englishman Abroad for the BBC World Service and repeated on various BBC radio formats since.
Following from the broadcast of 'Mrs. Warren's Profession', Wilton then had several major TV roles, including two of the BBC Television Shakespeare productions (as Desdemona in Othello and Regan in King Lear ).

Wilton's film career includes roles in The French Lieutenant's Woman (1981), Cry Freedom (1987), Iris (2001), Calendar Girls (2003) and Shaun of the Dead (2004), Jane Austen's Pride and Prejudice (2005), Woody Allen's Match Point (2005), and in The History Boys (2006).

She did not become a household name until she appeared with Richard Briers in the 1984 BBC situation comedy, Ever Decreasing Circles, which ran for five years.
She played Ann, long suffering wife of Martin (Briers), an obsessive and pedantic "do-gooder".
In 2005, Wilton guest starred as Harriet Jones for two episodes in the BBC's revival of the popular TV science-fiction series Doctor Who.
This guest role was written especially for her by the programme's chief writer and executive producer Russell T. Davies, with whom she had worked on Bob and Rose (ITV, 2001).
The character of Jones returned as Prime Minister in the Doctor Who 2005 Christmas special "The Christmas Invasion".
In the first part of the 2008 series finale, "The Stolen Earth", she made a final appearance, now as the former Prime Minister who sacrifices herself by extermination by the Daleks so that the Doctor's companions can contact him.

Wilton appeared on television as Barbara Poole, the mother of a missing woman, in the BBC television drama series Five Days in 2005; and in ITV's drama Half Broken Things (October 2007) and the BBC production of The Passion (Easter 2008).
Beginning in 2010, she appeared as Isobel Crawley in all six seasons of the hit period drama Downton Abbey.
She was the castaway on BBC Radio 4's Desert Island Discs in April 2008.
In December 2012 and February 2013, she was the narrator in Lin Coghlan's dramatisation of Elizabeth Jane Howard's The Cazalets, broadcast on BBC Radio.
Wilton began her career on stage in 1969 at the Nottingham Playhouse. Her early roles included Cordelia in King Lear, both in Nottingham and at The Old Vic.
She made her Broadway debut in March 1971 when she played Araminta in the original Broadway production of The Philanthropist, and made her West End debut in August 1971 opposite Sir Ralph Richardson, in the John Osborne play West of Suez at the Cambridge Theatre. She had previously appeared in both plays at the Royal Court Theatre. She played Ruth in the original 1974 London stage production of Alan Ayckbourn's Norman Conquests trilogy.
Her television acting career began in 1972, playing Vivie Warren in the BBC2's adaptation of Mrs. Warren's Profession opposite Coral Browne in the title role and Robert Powell. The production was repeated as part of the Play of the Month series in 1974 on BBC1. In 1994, Wilton portrayed Browne in a radio adaptation of An Englishman Abroad for the BBC World Service and repeated on various BBC radio formats since. Following from the broadcast of 'Mrs. Warren's Profession', Wilton then had several major TV roles, including two of the BBC Television Shakespeare productions (as Desdemona in Othello and Regan in King Lear ).
Wilton's film career includes roles in The French Lieutenant's Woman (1981), Cry Freedom (1987), Iris (2001), Calendar Girls (2003) and Shaun of the Dead (2004), Jane Austen's Pride and Prejudice (2005), Woody Allen's Match Point (2005), and in The History Boys (2006).
She did not become a household name until she appeared with Richard Briers in the 1984 BBC situation comedy, Ever Decreasing Circles, which ran for five years. She played Ann, long suffering wife of Martin (Briers), an obsessive and pedantic "do-gooder". In 2005, Wilton guest starred as Harriet Jones for two episodes in the BBC's revival of the popular TV science-fiction series Doctor Who. This guest role was written especially for her by the programme's chief writer and executive producer Russell T. Davies, with whom she had worked on Bob and Rose (ITV, 2001). The character of Jones returned as Prime Minister in the Doctor Who 2005 Christmas special "The Christmas Invasion". In the first part of the 2008 series finale, "The Stolen Earth", she made a final appearance, now as the former Prime Minister who sacrifices herself by extermination by the Daleks so that the Doctor's companions can contact him.
Wilton appeared on television as Barbara Poole, the mother of a missing woman, in the BBC television drama series Five Days in 2005; and in ITV's drama Half Broken Things (October 2007) and the BBC production of The Passion (Easter 2008). Beginning in 2010, she appeared as Isobel Crawley in all six seasons of the hit period drama Downton Abbey. She was the castaway on BBC Radio 4's Desert Island Discs in April 2008. In December 2012 and February 2013, she was the narrator in Lin Coghlan's dramatisation of Elizabeth Jane Howard's The Cazalets, broadcast on BBC Radio.
Penelope Wilton