The Leichhardt River divides the city into areas known as "mineside" and "townside".
Xstrata, the power station and the Airport are on the mineside, whilst the majority of the city, including the CBD and Base Hospital are on the townside.
In recent years, population increases associated with the mining boom has increased demand for accommodation and land.
 The city had spread out, with new suburbs in the south-east and north of the city being planned or developed.
Planned expansions can cater for more than 40,000 people.

Mineside
Happy Valley - includes Happy Valley State School, St Joseph's Catholic Primary School, and Captain James Cook Park
Kalkadoon - includes Mount Isa Airport and Kalkadoon Park
Mica Creek – includes CS Energy Mica Creek Power Station
Miles End - includes Mount Isa train station
Parkside – Mount Isa's largest and oldest suburb.
Contains the Irish Club, Parkside Flats complex, and Playway Park
Soldiers Hill – All streets and parks named after war locations and soldiers, such as Kokoda Road and Gallipoli Park
Hilton - More commonly known as Mineside, on the same side of the railway line as Mount Isa Mines and the Incitec Pivot Sulphuric Acid plant.
Employee housing, particularly for managers and visiting staff from Xstrata, Casa Grande; a white brick mansion built for the visit of Queen Elizabeth II; now used for the annual Casa Grande Ball, and some mine operations.

Townside
Breakaway Estate - Semi-rural acreages
Fisher
Healy - Residential suburb, site of Healy State School
Healy Heights - New suburb, development ongoing, with several houses finished.

Lanskey
Menzies – includes Buchanan Park events complex, Stables and Racecourse.

Mornington
Mount Isa City - The Central Business District
Mount Isa East – has own post office and smaller shopping centres
Pioneer – includes a campus of TAFE Queensland North, Spinifex Senior Campus and Ten-Pin Bowling complex, St Kierans Catholic Primary School
Ryan – mostly industrial, includes army and State Emergency Service barracks, home to one company of the 51st Battalion, Far North Queensland Regiment
Spreadborough - mostly bushland and light industry.
The notable Spreadborough family still resides in the area.

Sunset - Home to Sunset State Primary School, and some shopping facilities
The Gap
Townview - Home to Townview State Primary School
Winston
The Leichhardt River divides the city into areas known as "mineside" and "townside". Xstrata, the power station and the Airport are on the mineside, whilst the majority of the city, including the CBD and Base Hospital are on the townside. In recent years, population increases associated with the mining boom has increased demand for accommodation and land.  The city had spread out, with new suburbs in the south-east and north of the city being planned or developed. Planned expansions can cater for more than 40,000 people.
Mineside
Happy Valley - includes Happy Valley State School, St Joseph's Catholic Primary School, and Captain James Cook Park
Kalkadoon - includes Mount Isa Airport and Kalkadoon Park
Mica Creek – includes CS Energy Mica Creek Power Station
Miles End - includes Mount Isa train station
Parkside – Mount Isa's largest and oldest suburb. Contains the Irish Club, Parkside Flats complex, and Playway Park
Soldiers Hill – All streets and parks named after war locations and soldiers, such as Kokoda Road and Gallipoli Park
Hilton - More commonly known as Mineside, on the same side of the railway line as Mount Isa Mines and the Incitec Pivot Sulphuric Acid plant. Employee housing, particularly for managers and visiting staff from Xstrata, Casa Grande; a white brick mansion built for the visit of Queen Elizabeth II; now used for the annual Casa Grande Ball, and some mine operations.
Townside
Breakaway Estate - Semi-rural acreages
Fisher
Healy - Residential suburb, site of Healy State School
Healy Heights - New suburb, development ongoing, with several houses finished.
Lanskey
Menzies – includes Buchanan Park events complex, Stables and Racecourse.
Mornington
Mount Isa City - The Central Business District
Mount Isa East – has own post office and smaller shopping centres
Pioneer – includes a campus of TAFE Queensland North, Spinifex Senior Campus and Ten-Pin Bowling complex, St Kierans Catholic Primary School
Ryan – mostly industrial, includes army and State Emergency Service barracks, home to one company of the 51st Battalion, Far North Queensland Regiment
Spreadborough - mostly bushland and light industry. The notable Spreadborough family still resides in the area.
Sunset - Home to Sunset State Primary School, and some shopping facilities
The Gap
Townview - Home to Townview State Primary School
Winston
Mount Isa