Antigonus spent the winter of 316 BC in Media, whose ruler was once again Peithon.
Peithon's lust for power had grown, and he tried to get a portion of Antigonus' troops to revolt to his side.
Antigonus, however, discovered the plot and executed Peithon.
He then superseded Peucestas as satrap of Persia.
In the summer of 315 BC Antigonus arrived in Babylon and was warmly welcomed by Seleucus.
The relationship between the two soon turned cold, however.
Seleucus punished one of Antigonus' officers without asking permission from Antigonus.
Antigonus became angry and demanded that Seleucus give him the income from the province, which Seleucus refused to do.
He was, however, afraid of Antigonus and fled to Egypt with 50 horsemen.
It is told that Chaldean astrologers prophesied to Antigonus that Seleucus would become master of Asia and would kill Antigonus.
After hearing this, Antigonus sent soldiers after Seleucus, who had however first escaped to Mesopotamia and then to Syria.
Antigonus executed Blitor, the new satrap of Mesopotamia, for helping Seleucus.
Modern scholars are skeptical of the prophecy story.
It seems certain, however, that the Babylonian priesthood was against Seleucus.

During Seleucus' escape to Egypt, Macedonia was undergoing great turmoil.
Alexander the Great's mother Olympias had been invited back to Macedon by Polyperchon in order to drive Cassander out.
She held great respect among the Macedonian army but lost some of this when she had Philip III and his wife Eurydice killed as well as many nobles whom she took revenge upon for supporting Antipater during his long reign.
Cassander reclaimed Macedon the following year at Pydna and then had her killed.
Alexander IV, still a young child, and his mother Roxane were held guarded at Amphipolis and died under mysterious circumstances in 310 BC, probably murdered at the instigation of Cassander to allow the diadochs to assume the title of king.
Antigonus spent the winter of 316 BC in Media, whose ruler was once again Peithon. Peithon's lust for power had grown, and he tried to get a portion of Antigonus' troops to revolt to his side. Antigonus, however, discovered the plot and executed Peithon. He then superseded Peucestas as satrap of Persia. In the summer of 315 BC Antigonus arrived in Babylon and was warmly welcomed by Seleucus. The relationship between the two soon turned cold, however. Seleucus punished one of Antigonus' officers without asking permission from Antigonus. Antigonus became angry and demanded that Seleucus give him the income from the province, which Seleucus refused to do. He was, however, afraid of Antigonus and fled to Egypt with 50 horsemen. It is told that Chaldean astrologers prophesied to Antigonus that Seleucus would become master of Asia and would kill Antigonus. After hearing this, Antigonus sent soldiers after Seleucus, who had however first escaped to Mesopotamia and then to Syria. Antigonus executed Blitor, the new satrap of Mesopotamia, for helping Seleucus. Modern scholars are skeptical of the prophecy story. It seems certain, however, that the Babylonian priesthood was against Seleucus.
During Seleucus' escape to Egypt, Macedonia was undergoing great turmoil. Alexander the Great's mother Olympias had been invited back to Macedon by Polyperchon in order to drive Cassander out. She held great respect among the Macedonian army but lost some of this when she had Philip III and his wife Eurydice killed as well as many nobles whom she took revenge upon for supporting Antipater during his long reign. Cassander reclaimed Macedon the following year at Pydna and then had her killed. Alexander IV, still a young child, and his mother Roxane were held guarded at Amphipolis and died under mysterious circumstances in 310 BC, probably murdered at the instigation of Cassander to allow the diadochs to assume the title of king.
Seleucus I Nicator