Downingtown station is located along the Lincoln Highway and is served by both SEPTA Regional Rail's Paoli/Thorndale Line and Amtrak's Keystone Service.
 The town is also served by Krapf's Transit Route "A" bus between Coatesville and West Chester and the TMACC Evening Link bus between Coatesville and Exton; these routes are functionally an extension of the SEPTA bus system throughout Chester County.
 Both systems provide access to Philadelphia and other suburbs along the Main Line through the SEPTA and Amtrak train services.

PrimeRIDE Services is located in Downingtown.
PrimeRIDE offers transportation services.
Downingtown station is located along the Lincoln Highway and is served by both SEPTA Regional Rail's Paoli/Thorndale Line and Amtrak's Keystone Service.  The town is also served by Krapf's Transit Route "A" bus between Coatesville and West Chester and the TMACC Evening Link bus between Coatesville and Exton; these routes are functionally an extension of the SEPTA bus system throughout Chester County.  Both systems provide access to Philadelphia and other suburbs along the Main Line through the SEPTA and Amtrak train services.
PrimeRIDE Services is located in Downingtown. PrimeRIDE offers transportation services.
Downingtown, Pennsylvania