Wheaton was a contestant on a 2001 episode of The Weakest Link featuring Star Trek actors attempting to win money for charity.
He has made guest appearances on the November 23, 2007, episode of the TV series Numb3rs, and the October 22, 2008, episode of the series Criminal Minds, and appeared in Internet presentations, including a cameo in a comedy sketch ("Lock Out") for LoadingReadyRun (and a reprise of the same the following year, in CommodoreHustle 4), and the May 30, 2008, episode of the Internet series Gorgeous Tiny Chicken Machine Show.
From 2009-2011, Wheaton appeared in seasons 3, 4, and 5 of the web series The Guild as Fawkes, the leader for a rival guild known as Axis of Anarchy.
Wheaton credits his roles in Gorgeous Tiny Chicken Machine Show and The Guild for reigniting his career by encouraging him to seek out roles as the "Villain You Love To Hate" stock character.
He also appears in seasons 2, 3, and 4 of the television series Leverage, as rival computer hacker Colin "Chaos" Mason, antagonist to Leverage team hacker Alec Hardison.
He makes regular appearances in many web productions for Geek & Sundry, including hosting TableTop, a board game based show, and Titansgrave, a roleplaying game based show.

He appeared as a fictionalized version of himself in several episodes of the sitcom The Big Bang Theory, starting in season 3, episode 4: "The Creepy Candy Coating Corollary" (2009).
On the show, Wheaton behaves in comically petty and manipulative ways towards main character Sheldon Cooper, who regards him as an archenemy until the season 5 episode "The Russian Rocket Reaction", when they make amends and become friends.
Wheaton appears in 12 episodes in a recurring, guest-starring role on Eureka, playing Dr. Isaac Parrish, the head of the Non-Lethal Weapons Lab at Global Dynamics and a thorn in Fargo's side.
Wheaton also voices the character of the former scoutmaster and current sous-chef Earl Harlan in the popular dark, surreal-comedy podcast Welcome to Night Vale.

Wheaton played Alexander Rook in the Syfy TV series Dark Matter, based on the eponymous comic book.
Wheaton was a contestant on a 2001 episode of The Weakest Link featuring Star Trek actors attempting to win money for charity. He has made guest appearances on the November 23, 2007, episode of the TV series Numb3rs, and the October 22, 2008, episode of the series Criminal Minds, and appeared in Internet presentations, including a cameo in a comedy sketch ("Lock Out") for LoadingReadyRun (and a reprise of the same the following year, in CommodoreHustle 4), and the May 30, 2008, episode of the Internet series Gorgeous Tiny Chicken Machine Show. From 2009-2011, Wheaton appeared in seasons 3, 4, and 5 of the web series The Guild as Fawkes, the leader for a rival guild known as Axis of Anarchy. Wheaton credits his roles in Gorgeous Tiny Chicken Machine Show and The Guild for reigniting his career by encouraging him to seek out roles as the "Villain You Love To Hate" stock character. He also appears in seasons 2, 3, and 4 of the television series Leverage, as rival computer hacker Colin "Chaos" Mason, antagonist to Leverage team hacker Alec Hardison. He makes regular appearances in many web productions for Geek & Sundry, including hosting TableTop, a board game based show, and Titansgrave, a roleplaying game based show.
He appeared as a fictionalized version of himself in several episodes of the sitcom The Big Bang Theory, starting in season 3, episode 4: "The Creepy Candy Coating Corollary" (2009). On the show, Wheaton behaves in comically petty and manipulative ways towards main character Sheldon Cooper, who regards him as an archenemy until the season 5 episode "The Russian Rocket Reaction", when they make amends and become friends. Wheaton appears in 12 episodes in a recurring, guest-starring role on Eureka, playing Dr. Isaac Parrish, the head of the Non-Lethal Weapons Lab at Global Dynamics and a thorn in Fargo's side. Wheaton also voices the character of the former scoutmaster and current sous-chef Earl Harlan in the popular dark, surreal-comedy podcast Welcome to Night Vale.
Wheaton played Alexander Rook in the Syfy TV series Dark Matter, based on the eponymous comic book.
Wil Wheaton