In March 1925 Curzon suffered a severe haemorrhage of the bladder.
Surgery was unsuccessful and he died in London on 20 March 1925 at the age of 66.
His coffin, made from the same tree at Kedleston that had encased his first wife, Mary, was taken to Westminster Abbey and from there to his ancestral home in Derbyshire, where he was interred beside Mary in the family vault at All Saints Church on 26 March.
In his will, proven on 22 July, Curzon bequeathed his estate to his wife and his brother Francis; his estate was valued for probate at £343,279 10s.
4d. (
roughly equivalent to £19,723,149 in 2019).

Upon his death the Barony, Earldom and Marquessate of Curzon of Kedleston and the Earldom of Kedleston became extinct, whilst the Viscountcy and Barony of Scarsdale were inherited by a nephew.
The Barony of Ravensdale was inherited by his eldest daughter Mary and is today held by his second daughter Cynthia's great-grandson, Daniel Nicholas Mosley, 4th Baron Ravensdale.

There is now a blue plaque on the house in London where Curzon lived and died, No.
1 Carlton House Terrace, Westminster.
In March 1925 Curzon suffered a severe haemorrhage of the bladder. Surgery was unsuccessful and he died in London on 20 March 1925 at the age of 66. His coffin, made from the same tree at Kedleston that had encased his first wife, Mary, was taken to Westminster Abbey and from there to his ancestral home in Derbyshire, where he was interred beside Mary in the family vault at All Saints Church on 26 March. In his will, proven on 22 July, Curzon bequeathed his estate to his wife and his brother Francis; his estate was valued for probate at £343,279 10s. 4d. (roughly equivalent to £19,723,149 in 2019).
Upon his death the Barony, Earldom and Marquessate of Curzon of Kedleston and the Earldom of Kedleston became extinct, whilst the Viscountcy and Barony of Scarsdale were inherited by a nephew. The Barony of Ravensdale was inherited by his eldest daughter Mary and is today held by his second daughter Cynthia's great-grandson, Daniel Nicholas Mosley, 4th Baron Ravensdale.
There is now a blue plaque on the house in London where Curzon lived and died, No. 1 Carlton House Terrace, Westminster.
George Curzon, 1st Marquess Curzon of Kedleston