His brother David is buried at Crosbie church and his daughter married into the Fullarton of Crosbie family and another daughter, Alison, married Gavin Hamilton, Bishop of Galloway.
A Fullarton family tradition suggests that this David Hamilton may have been closely involved in or might even have been the true assassin of the Earl of Moray.
David had been forfeited and excluded from the 1573 Treaty of Perth, however his lands were returned to him by an act of 1592.

In the apparent absence of recorded legal repercussions, a 19th-century historian, John Bain, put forward the view of his patron John Smith of Swindrigemuir, that David and James Hamilton probably were present at Linlithgow and their servant Pate Wilson may have fired the fatal shot.

In 1545 John Hamilton, Abbot of Paisley, feued to his kinsman David Hamilton and his wife Christian Shaw (who may have been a close relation of the Abbot), James's father, the lands of Monktonmains (later known as Fairfield) near Prestwick.
Thus James's younger brother David, who died in 1619, was Hamilton of Monktonmains and also Bothwellhaugh.
Hamilton of Wishaw has it that David died in 1613.
John Colville wrote that David participated in the struggle at Stirling in September 1571 when Regent Lennox was killed.
His brother David is buried at Crosbie church and his daughter married into the Fullarton of Crosbie family and another daughter, Alison, married Gavin Hamilton, Bishop of Galloway. A Fullarton family tradition suggests that this David Hamilton may have been closely involved in or might even have been the true assassin of the Earl of Moray. David had been forfeited and excluded from the 1573 Treaty of Perth, however his lands were returned to him by an act of 1592.
In the apparent absence of recorded legal repercussions, a 19th-century historian, John Bain, put forward the view of his patron John Smith of Swindrigemuir, that David and James Hamilton probably were present at Linlithgow and their servant Pate Wilson may have fired the fatal shot.
In 1545 John Hamilton, Abbot of Paisley, feued to his kinsman David Hamilton and his wife Christian Shaw (who may have been a close relation of the Abbot), James's father, the lands of Monktonmains (later known as Fairfield) near Prestwick. Thus James's younger brother David, who died in 1619, was Hamilton of Monktonmains and also Bothwellhaugh. Hamilton of Wishaw has it that David died in 1613. John Colville wrote that David participated in the struggle at Stirling in September 1571 when Regent Lennox was killed.
James Hamilton (assassin)