On 21 March, Task Group 51.1, known as the Western Islands Attack Group, departed for the Kerama Islands, which it was to secure before the invasion of Okinawa.
Oberrender was included in the task group screen with Task Unit 51.1.13, which also included Richard W. Suesens and Abercrombie from CortDiv 69 as well as the destroyers Picking, Sproston, Isherwood, William D. Porter, Charles J. Badger and Kimberly of Destroyer Squadron 49.
They arrived in the area of Kerama Retto on 26 March, and while the troops quickly secured the islands, Oberrender was placed on anti-submarine patrol.
On the night of 29 March her lookouts spotted a Japanese G4M Betty bomber, flying above the transports she was escorting for the night.
This was Oberrender's first Japanese aircraft sighting of the campaign.
She fruitlessly fired 20 mm rounds at the aircraft, which did not attack.

When the invasion of Okinawa began on 1 April, known as L-Day, the task unit was dissolved and Task Group 51.5 under Captain Frederick Moosbrugger assumed control of the screen, in the waters surrounding the island, including Oberrender on anti-submarine patrol.
Air attacks became more frequent, but she remained untouched, driving off a Zero and a D3A Val dive bomber with her AA fire in two separate actions on 2 April.
A day later, the ship stood alongside fellow destroyer escort Foreman was damaged by a bomb, and she temporarily left her patrol station to escort the attack transport Kenton into Hagushi Bay.
Oberrender departed Okinawa to escort attack transports returning to Saipan on 5 April, returning to Okinawa after a stopover at Ulithi on 17 April.

Back in the Okinawa vicinity, she and fellow destroyer escort England operated as an anti-submarine hunter-killer group for the next several days, on one occasion firing her Hedgehog (weapon) at several contacts that turned out to be schools of fish.
After returning to her patrol station separately from England in late April, Oberrender briefly returned to the Kerama Islands for resupply on 30 April, then resumed her station later that day.
For the next few days, the routine of patrolling was broken by the escort of transports from Hagushi Beach to Nakagusuku Bay on 2 May and a fruitless engagement with a G3M Nell bomber.

While stationed with the outer anti-submarine screen to the west of the island on 9 May, Oberrender went to general quarters after receiving a report of an approaching kamikaze attack at 18:40.
After picking up a lone Japanese aircraft on her radar ten minutes later, she increased to flank speed.
Her lookouts sighted the plane at 18:52, and it entered a dive toward the ship.
One of its wings was torn off by her anti-aircraft fire, causing the aircraft to veer to the right, but it still crashed into the starboard 20 mm mount, destroying the latter.
The bomb carried by the aircraft penetrated the main deck and exploded in the forward fireroom, knocking out power and leaving her dead in the water.
The explosion heavily damaged the ship and nearly broke her in half, blowing the starboard hull plating outwards for a quarter of her length and pushing up the main deck.
 In the attack, eight men were killed and fifty-three wounded; those killed were either in the forward fireroom or the 20 mm mount that the plane crashed into.
Oberrender transferred her wounded to rescue patrol craft escort PCE(R)-855 and was towed to Kerama Retto by the fleet tug Tekesta.
Declared to be a constructive total loss, she was decommissioned on 11 July and struck from the Naval Vessel Register on 25 July.
Her serviceable equipment was removed and the hulk was used as a target for gunnery practice, being sunk on 6 November 1945.
On 21 March, Task Group 51.1, known as the Western Islands Attack Group, departed for the Kerama Islands, which it was to secure before the invasion of Okinawa. Oberrender was included in the task group screen with Task Unit 51.1.13, which also included Richard W. Suesens and Abercrombie from CortDiv 69 as well as the destroyers Picking, Sproston, Isherwood, William D. Porter, Charles J. Badger and Kimberly of Destroyer Squadron 49. They arrived in the area of Kerama Retto on 26 March, and while the troops quickly secured the islands, Oberrender was placed on anti-submarine patrol. On the night of 29 March her lookouts spotted a Japanese G4M Betty bomber, flying above the transports she was escorting for the night. This was Oberrender's first Japanese aircraft sighting of the campaign. She fruitlessly fired 20 mm rounds at the aircraft, which did not attack.
When the invasion of Okinawa began on 1 April, known as L-Day, the task unit was dissolved and Task Group 51.5 under Captain Frederick Moosbrugger assumed control of the screen, in the waters surrounding the island, including Oberrender on anti-submarine patrol. Air attacks became more frequent, but she remained untouched, driving off a Zero and a D3A Val dive bomber with her AA fire in two separate actions on 2 April. A day later, the ship stood alongside fellow destroyer escort Foreman was damaged by a bomb, and she temporarily left her patrol station to escort the attack transport Kenton into Hagushi Bay. Oberrender departed Okinawa to escort attack transports returning to Saipan on 5 April, returning to Okinawa after a stopover at Ulithi on 17 April.
Back in the Okinawa vicinity, she and fellow destroyer escort England operated as an anti-submarine hunter-killer group for the next several days, on one occasion firing her Hedgehog (weapon) at several contacts that turned out to be schools of fish. After returning to her patrol station separately from England in late April, Oberrender briefly returned to the Kerama Islands for resupply on 30 April, then resumed her station later that day. For the next few days, the routine of patrolling was broken by the escort of transports from Hagushi Beach to Nakagusuku Bay on 2 May and a fruitless engagement with a G3M Nell bomber.
While stationed with the outer anti-submarine screen to the west of the island on 9 May, Oberrender went to general quarters after receiving a report of an approaching kamikaze attack at 18:40. After picking up a lone Japanese aircraft on her radar ten minutes later, she increased to flank speed. Her lookouts sighted the plane at 18:52, and it entered a dive toward the ship. One of its wings was torn off by her anti-aircraft fire, causing the aircraft to veer to the right, but it still crashed into the starboard 20 mm mount, destroying the latter. The bomb carried by the aircraft penetrated the main deck and exploded in the forward fireroom, knocking out power and leaving her dead in the water. The explosion heavily damaged the ship and nearly broke her in half, blowing the starboard hull plating outwards for a quarter of her length and pushing up the main deck.  In the attack, eight men were killed and fifty-three wounded; those killed were either in the forward fireroom or the 20 mm mount that the plane crashed into. Oberrender transferred her wounded to rescue patrol craft escort PCE(R)-855 and was towed to Kerama Retto by the fleet tug Tekesta. Declared to be a constructive total loss, she was decommissioned on 11 July and struck from the Naval Vessel Register on 25 July. Her serviceable equipment was removed and the hulk was used as a target for gunnery practice, being sunk on 6 November 1945.
USS Oberrender