The events of September 11, 2001, dramatically affected Boquillas del Carmen's 20th-century way of life.
In May 2002, the border crossing from Big Bend National Park to Boquillas was closed indefinitely.
By October 2006, only 19 families comprising around 90 to 100 residents remained in Boquillas.
Most of the town's residents had been forced to move away by the closure of the tourist crossing and destruction of the town's traditional economy.
 At the time of the 2010 census, the town's population was recorded as comprising only 110 people.

On January 7, 2011, the US National Park Service announced plans to reopen the crossing using a ferry and a passport control center planned to open in the spring of 2012.
After multiple delays, the new Boquillas Port of Entry was finally officially opened on 10 April 2013.
 The hours of operation currently are 9 a.m. to 6 p.m., Wednesday through Sunday, subject to seasonal changes.
 Since opening of the border crossing, the town of Boquillas del Carmen has seen substantial growth with the addition of electricity (from solar panels), a new medical care office, and enhancements at the public elementary school.
The village's population is now said to be about 200 persons.
 Visitors are allowed to bring one bottle of alcohol back to the U.S. via this entry point.
One may not bring tobacco back to the U.S. via this entry point.
The events of September 11, 2001, dramatically affected Boquillas del Carmen's 20th-century way of life. In May 2002, the border crossing from Big Bend National Park to Boquillas was closed indefinitely. By October 2006, only 19 families comprising around 90 to 100 residents remained in Boquillas. Most of the town's residents had been forced to move away by the closure of the tourist crossing and destruction of the town's traditional economy.  At the time of the 2010 census, the town's population was recorded as comprising only 110 people.
On January 7, 2011, the US National Park Service announced plans to reopen the crossing using a ferry and a passport control center planned to open in the spring of 2012. After multiple delays, the new Boquillas Port of Entry was finally officially opened on 10 April 2013.  The hours of operation currently are 9 a.m. to 6 p.m., Wednesday through Sunday, subject to seasonal changes.  Since opening of the border crossing, the town of Boquillas del Carmen has seen substantial growth with the addition of electricity (from solar panels), a new medical care office, and enhancements at the public elementary school. The village's population is now said to be about 200 persons.  Visitors are allowed to bring one bottle of alcohol back to the U.S. via this entry point. One may not bring tobacco back to the U.S. via this entry point.
Boquillas del Carmen