His first release of 2010 was the dystopian romance Never Let Me Go, starring Carey Mulligan, Keira Knightley, and Andrew Garfield.
Harry Potter and the Deathly Hallows – Part 1 was released in November 2010, with the Part 2 being released the following July.
His portrayal of Bill Weasley, Ron Weasley's older brother, exposed Gleeson to a wider audience.
The multi Academy Award nominated Coen Brothers' film True Grit featured Gleeson as Moon, a young outlaw.
His short comedy film, Noreen, starring his father and brother, was shown at the Tribeca Film Festival.
He portrayed musician Bob Geldof as he organises the 1985 Live Aid concert in the television film When Harvey Met Bob, which was broadcast on BBC Four on 26 December 2010.
Gleeson won the 2011 Ifta Award for Best Actor for his performance in the film.

In the drama Shadow Dancer, released in August 2012, he played an IRA member whose own sister informs on him to the MI5.
Gleeson played landowner Kostya Levin in the historical romance Anna Karenina, based on the Leo Tolstoy novel.
The Daily Telegraph critic Tim Robey praised his performance, saying Gleeson "nails Levin’s adorable self-seriousness without sentimentalising what can make him hard work."
His final release of 2012 was the science fiction action film Dredd starring Karl Urban as the titular Judge Dredd, in which he played an unnamed computer expert working for the gang Dredd battles against.

Gleeson made a guest appearance in "Be Right Back", an episode of the science-fiction anthology series Black Mirror in 2013.
Starring alongside Hayley Atwell, he played a man who is killed in a car crash, but returns to his lover as an synthetic android clone of himself.
Later in 2013, Gleeson starred in About Time, a romantic comedy written and directed by Richard Curtis.
The story follows a young man, played by Gleeson, who uses time travel to win over an American girl, played by Rachel McAdams.
Filming took place in London, England, in June 2012.
In a largely negative review, Catherine Shaord of The Guardian described Gleeson as a "ginger Hugh Grant", although she noted that "The effect, at first, is unnerving; as About Time marches on, Gleeson's innate charm gleams through and this weird disconnection becomes quite compelling."

In Lenny Abrahamson's Frank (2014), he portrayed Jon, a wannabe musician who joins the band of the eccentric, papier-mâché head-wearing titular character played by Michael Fassbender.
Gleeson played a small role as a psychotic killer in the Irish drama Calvary, starring his father as a Catholic priest who visits him in prison.
His last release of 2014, was Angelina Jolie's directorial debut, the war film Unbroken.
In the film, Gleeson portrayed a soldier lost at sea after a plane crash in Pacific Ocean during the Second World War.
He lost what he described as a "sizable amount of weight" for the role.
Along with his father and brother Brian, Gleeson created and stars in the Immatürity For Charity comedy sketches, which raise money for the St. Francis Hospice in Raheny, Dublin.
Gleeson directed and starred in a music video for the Squarehead charity single "2025" in 2014, with all proceeds going to Immatürity For Charity.
His first release of 2010 was the dystopian romance Never Let Me Go, starring Carey Mulligan, Keira Knightley, and Andrew Garfield. Harry Potter and the Deathly Hallows – Part 1 was released in November 2010, with the Part 2 being released the following July. His portrayal of Bill Weasley, Ron Weasley's older brother, exposed Gleeson to a wider audience. The multi Academy Award nominated Coen Brothers' film True Grit featured Gleeson as Moon, a young outlaw. His short comedy film, Noreen, starring his father and brother, was shown at the Tribeca Film Festival. He portrayed musician Bob Geldof as he organises the 1985 Live Aid concert in the television film When Harvey Met Bob, which was broadcast on BBC Four on 26 December 2010. Gleeson won the 2011 Ifta Award for Best Actor for his performance in the film.
In the drama Shadow Dancer, released in August 2012, he played an IRA member whose own sister informs on him to the MI5. Gleeson played landowner Kostya Levin in the historical romance Anna Karenina, based on the Leo Tolstoy novel. The Daily Telegraph critic Tim Robey praised his performance, saying Gleeson "nails Levin’s adorable self-seriousness without sentimentalising what can make him hard work." His final release of 2012 was the science fiction action film Dredd starring Karl Urban as the titular Judge Dredd, in which he played an unnamed computer expert working for the gang Dredd battles against.
Gleeson made a guest appearance in "Be Right Back", an episode of the science-fiction anthology series Black Mirror in 2013. Starring alongside Hayley Atwell, he played a man who is killed in a car crash, but returns to his lover as an synthetic android clone of himself. Later in 2013, Gleeson starred in About Time, a romantic comedy written and directed by Richard Curtis. The story follows a young man, played by Gleeson, who uses time travel to win over an American girl, played by Rachel McAdams. Filming took place in London, England, in June 2012. In a largely negative review, Catherine Shaord of The Guardian described Gleeson as a "ginger Hugh Grant", although she noted that "The effect, at first, is unnerving; as About Time marches on, Gleeson's innate charm gleams through and this weird disconnection becomes quite compelling."
In Lenny Abrahamson's Frank (2014), he portrayed Jon, a wannabe musician who joins the band of the eccentric, papier-mâché head-wearing titular character played by Michael Fassbender. Gleeson played a small role as a psychotic killer in the Irish drama Calvary, starring his father as a Catholic priest who visits him in prison. His last release of 2014, was Angelina Jolie's directorial debut, the war film Unbroken. In the film, Gleeson portrayed a soldier lost at sea after a plane crash in Pacific Ocean during the Second World War. He lost what he described as a "sizable amount of weight" for the role. Along with his father and brother Brian, Gleeson created and stars in the Immatürity For Charity comedy sketches, which raise money for the St. Francis Hospice in Raheny, Dublin. Gleeson directed and starred in a music video for the Squarehead charity single "2025" in 2014, with all proceeds going to Immatürity For Charity.
Domhnall Gleeson