From 1815 to 1834, Campbell and his father kept the Brush Run Church affiliated with a local Baptist association.
After disagreements over some issues, they allied with the Mahoning Baptist Association.

Campbell's only formal political service was as a delegate to the Virginia Constitutional Convention of 1829–1830, held in Richmond.
He met some of the leading politicians of the day and was invited to preach in several churches in the capital city.

In 1840, Campbell founded Bethany College in Bethany, Virginia (now West Virginia).
He believed that the clergy should be college educated.
Many future leaders of the Disciples of Christ and Churches of Christ graduated from the college, although some latter congregations did not attach the same value to theological study and professional clergy.

Campbell visited the United Kingdom in 1847.
During the trip he gave public lectures in England and Scotland.
He went to Ireland to deliver funds that U.S. Restoration Movement churches had raised for relief in the Great Famine.
While at Glasgow, he was challenged by James Robertson to a debate on the subject of slavery, which the American South protected and Campbell defended as moral.
As a result of the fierce exchange, Robertson sued Campbell for libel.
The American denied the charge, but he was arrested and imprisoned for ten days.
Campbell was released when the warrant for his arrest was declared to be illegal.
The case was ultimately tried, and the jury decided in his favor.
From 1815 to 1834, Campbell and his father kept the Brush Run Church affiliated with a local Baptist association. After disagreements over some issues, they allied with the Mahoning Baptist Association.
Campbell's only formal political service was as a delegate to the Virginia Constitutional Convention of 1829–1830, held in Richmond. He met some of the leading politicians of the day and was invited to preach in several churches in the capital city.
In 1840, Campbell founded Bethany College in Bethany, Virginia (now West Virginia). He believed that the clergy should be college educated. Many future leaders of the Disciples of Christ and Churches of Christ graduated from the college, although some latter congregations did not attach the same value to theological study and professional clergy.
Campbell visited the United Kingdom in 1847. During the trip he gave public lectures in England and Scotland. He went to Ireland to deliver funds that U.S. Restoration Movement churches had raised for relief in the Great Famine. While at Glasgow, he was challenged by James Robertson to a debate on the subject of slavery, which the American South protected and Campbell defended as moral. As a result of the fierce exchange, Robertson sued Campbell for libel. The American denied the charge, but he was arrested and imprisoned for ten days. Campbell was released when the warrant for his arrest was declared to be illegal. The case was ultimately tried, and the jury decided in his favor.
Alexander Campbell (minister)