The Squadron arrived at the RAF Mount Farm airfield on 8 June 1943.
The unit was equipped with Lockheed F-5 (P-38) Lightning photographic aircraft and the first mission was flown on 24 June 1943.
The 22nd Reconnaissance Squadron was combined with the 13th Photographic Squadron and 14th Photographic Squadron, into the 7th Photographic Reconnaissance and Mapping Group that was activated on 7 July 1943.

In 1943, the 22nd was among the squadrons flying the first photoreconnaissance missions against Peenemünde.

During August and September 1945, personnel were transferred out of the 22nd squadron, some returning to the United States and others assigned to the Occupation Forces in Germany.
The Squadron arrived at the RAF Mount Farm airfield on 8 June 1943. The unit was equipped with Lockheed F-5 (P-38) Lightning photographic aircraft and the first mission was flown on 24 June 1943. The 22nd Reconnaissance Squadron was combined with the 13th Photographic Squadron and 14th Photographic Squadron, into the 7th Photographic Reconnaissance and Mapping Group that was activated on 7 July 1943.
In 1943, the 22nd was among the squadrons flying the first photoreconnaissance missions against Peenemünde.
During August and September 1945, personnel were transferred out of the 22nd squadron, some returning to the United States and others assigned to the Occupation Forces in Germany.
22nd Photographic Reconnaissance Squadron