On 11 June 2017, Leadsom was appointed Lord President of the Council and Leader of the House of Commons.
In this capacity, in July 2017, while attempting to eulogise Jane Austen, who was about to feature on the new £10 note scheduled to go into circulation in September, Leadsom told the House of Commons: "I would just add one other great lady to that lovely list, who I am delighted to join in celebrating, and that's that of Jane Austen, who will feature on the new £10 note, which I think is one of our greatest living authors."
Amid laughs from both benches, she corrected herself, adding: "Greatest ever authors, and I think it's fantastic that at last we are starting to recognize – well I think many of us probably wish she were still living – but I absolutely share the sentiment."

On 14 January 2019, Leadsom was criticised in the House of Commons by the Speaker of the House, John Bercow for the failure of the government to advance the cause of proxy voting for expectant mothers.
The issue came to a head due to the imminent caesarean section delivery by Tulip Siddiq at the time of the rescheduled meaningful vote on 15 January 2019.

On 31 January 2019, Leadsom said the House of Commons' February recess from 15 to 24 February would be cancelled to free up time to pass the necessary Brexit-related legislation.
Earlier in the day, her cabinet colleague Jeremy Hunt raised the possibility of Brexit being delayed with a technical extension to Article 50.
The Times newspaper reported that senior Government ministers fear that it is already too late to meet the Brexit deadline of 29 March, and that Conservative MPs have been told that a one-line whip is expected to be imposed on votes in the Commons during the week of 18–22 February.

Leadsom resigned as Leader of the House of Commons on 22 May, the eve of the European elections, as a result of Theresa May's most recent Brexit proposals, including the offer of votes in the House of Commons on a customs union and a second referendum.
On 11 June 2017, Leadsom was appointed Lord President of the Council and Leader of the House of Commons. In this capacity, in July 2017, while attempting to eulogise Jane Austen, who was about to feature on the new £10 note scheduled to go into circulation in September, Leadsom told the House of Commons: "I would just add one other great lady to that lovely list, who I am delighted to join in celebrating, and that's that of Jane Austen, who will feature on the new £10 note, which I think is one of our greatest living authors." Amid laughs from both benches, she corrected herself, adding: "Greatest ever authors, and I think it's fantastic that at last we are starting to recognize – well I think many of us probably wish she were still living – but I absolutely share the sentiment."
On 14 January 2019, Leadsom was criticised in the House of Commons by the Speaker of the House, John Bercow for the failure of the government to advance the cause of proxy voting for expectant mothers. The issue came to a head due to the imminent caesarean section delivery by Tulip Siddiq at the time of the rescheduled meaningful vote on 15 January 2019.
On 31 January 2019, Leadsom said the House of Commons' February recess from 15 to 24 February would be cancelled to free up time to pass the necessary Brexit-related legislation. Earlier in the day, her cabinet colleague Jeremy Hunt raised the possibility of Brexit being delayed with a technical extension to Article 50. The Times newspaper reported that senior Government ministers fear that it is already too late to meet the Brexit deadline of 29 March, and that Conservative MPs have been told that a one-line whip is expected to be imposed on votes in the Commons during the week of 18–22 February.
Leadsom resigned as Leader of the House of Commons on 22 May, the eve of the European elections, as a result of Theresa May's most recent Brexit proposals, including the offer of votes in the House of Commons on a customs union and a second referendum.
Andrea Leadsom