Liverpool's first wife, Louisa, died at 54.
He soon married again, on 24 September 1822, to Lady Mary Chester, a long-time friend of Louisa.
 Liverpool finally retired on 9 April 1827 after suffering a severe cerebral hemorrhage at his Fife House residence in Whitehall two months earlier, and asked the King to seek a successor.
He suffered another minor stroke in July, after which he lingered on at Coombe until a third attack on 4 December 1828 from which he died.
Having died childless, he was succeeded as Earl of Liverpool by his younger half-brother Charles.
He was buried in Hawkesbury parish church, Gloucestershire, beside his father and his first wife.
His personal estate was registered at under £120,000.
Liverpool's first wife, Louisa, died at 54. He soon married again, on 24 September 1822, to Lady Mary Chester, a long-time friend of Louisa.  Liverpool finally retired on 9 April 1827 after suffering a severe cerebral hemorrhage at his Fife House residence in Whitehall two months earlier, and asked the King to seek a successor. He suffered another minor stroke in July, after which he lingered on at Coombe until a third attack on 4 December 1828 from which he died. Having died childless, he was succeeded as Earl of Liverpool by his younger half-brother Charles. He was buried in Hawkesbury parish church, Gloucestershire, beside his father and his first wife. His personal estate was registered at under £120,000.
Robert Jenkinson, 2nd Earl of Liverpool