William Greene married his second cousin, Catharine Greene, the daughter of Benjamin and Susanna (Holden) Greene, a granddaughter of Randall Holden, and a great granddaughter of the first John Greene Sr..  The couple had six children, five of whom survived to adulthood.
 Their son, William Greene Jr. became the second governor after Rhode Island became a state.
William Greene married his second cousin, Catharine Greene, the daughter of Benjamin and Susanna (Holden) Greene, a granddaughter of Randall Holden, and a great granddaughter of the first John Greene Sr..  The couple had six children, five of whom survived to adulthood.  Their son, William Greene Jr. became the second governor after Rhode Island became a state.
William Greene (colonial governor)