In May 2015, Whitcomb signed with the Perth Lynx for the 2015–16 WNBL season.
She earned eight Team of the Week recognitions, was named Player of the Week for Round 3, and helped the Lynx reach their first WNBL Grand Final since 1999.
In the grand final series, the Lynx were defeated 2–º by the Townsville Fire despite Whitcomb's 20 points in game one and 15 points in game two.
For the season, Whitcomb earned WNBL All-Star Five honors and finished third in MVP voting.
She appeared in all 27 games for the Lynx in 2015–16, averaging 19.4 points, 5.7 rebounds, 2.9 assists and 2.8 steals per game.

Whitcomb re-joined the Lynx for the 2016–17 season and earned Player of the Week honors for Round 3, Player of the Month honors for October, and had 13 Team of the Week recognitions.
Her 23.6 points and 2.8 steals per game were first in the WNBL for the regular season, while her 91 three-pointers set a WNBL single-season record.
Her 567 total points was also the second best mark ever set in the WNBL regular season—Penny Taylor had 570 in 2002.
In the semi-finals, Whitcomb scored a career-high 41 points.
She was named to the WNBL All-Star Five for the second consecutive season, after delivering the greatest scoring season in league history.
She tallied 652 points throughout her 27 games, the highest single season points total in the WNBL's 36-year history.
She finished the season with averages of 24.1 points, 5.2 rebounds and 3.9 assists per game, while knocking down 105 three-pointers throughout the year, besting her own WNBL record for most three-pointers made in a season.

Whitcomb returned to the Lynx for a third season in 2017–18 and was named co-captain.
She helped the Lynx record their first 10-game win streak since 1993, with the streak finally ending after 14 straight wins culminating in claiming the minor premiership with a first-place finish and a 15–6 record.
For the season, she earned one Player of the Week award, five Team of the Week selections, and All-Star Five honors for the third consecutive season.
She appeared in all 23 games for the Lynx in 2017–18, averaging 17.2 points, 5.2 rebounds, 4.3 assists and 2.6 steals per game.
She parted ways with the Lynx following the season.

Whitcomb made a return to the Lynx in June 2020, signing for the 2020–21 WNBL season.
In May 2015, Whitcomb signed with the Perth Lynx for the 2015–16 WNBL season. She earned eight Team of the Week recognitions, was named Player of the Week for Round 3, and helped the Lynx reach their first WNBL Grand Final since 1999. In the grand final series, the Lynx were defeated 2–º by the Townsville Fire despite Whitcomb's 20 points in game one and 15 points in game two. For the season, Whitcomb earned WNBL All-Star Five honors and finished third in MVP voting. She appeared in all 27 games for the Lynx in 2015–16, averaging 19.4 points, 5.7 rebounds, 2.9 assists and 2.8 steals per game.
Whitcomb re-joined the Lynx for the 2016–17 season and earned Player of the Week honors for Round 3, Player of the Month honors for October, and had 13 Team of the Week recognitions. Her 23.6 points and 2.8 steals per game were first in the WNBL for the regular season, while her 91 three-pointers set a WNBL single-season record. Her 567 total points was also the second best mark ever set in the WNBL regular season—Penny Taylor had 570 in 2002. In the semi-finals, Whitcomb scored a career-high 41 points. She was named to the WNBL All-Star Five for the second consecutive season, after delivering the greatest scoring season in league history. She tallied 652 points throughout her 27 games, the highest single season points total in the WNBL's 36-year history. She finished the season with averages of 24.1 points, 5.2 rebounds and 3.9 assists per game, while knocking down 105 three-pointers throughout the year, besting her own WNBL record for most three-pointers made in a season.
Whitcomb returned to the Lynx for a third season in 2017–18 and was named co-captain. She helped the Lynx record their first 10-game win streak since 1993, with the streak finally ending after 14 straight wins culminating in claiming the minor premiership with a first-place finish and a 15–6 record. For the season, she earned one Player of the Week award, five Team of the Week selections, and All-Star Five honors for the third consecutive season. She appeared in all 23 games for the Lynx in 2017–18, averaging 17.2 points, 5.2 rebounds, 4.3 assists and 2.6 steals per game. She parted ways with the Lynx following the season.
Whitcomb made a return to the Lynx in June 2020, signing for the 2020–21 WNBL season.
Sami Whitcomb