The band were first introduced to the acid house scene by McGee in 1988.
They were at first sceptical; Gillespie said: "I always remember being quite fascinated by it but not quite getting it."
The band developed a taste for it and began attending raves.
The band met up with DJ Andrew Weatherall at a rave, and he was given a copy of "I'm Losing More Than I'll Ever Have", a track from Primal Scream, to remix for one of his shows.
Weatherall added a drum loop from an Italian bootleg mix of Edie Brickell's "What I Am", a sample of Gillespie singing a line from Robert Johnson's "Terraplane Blues" and the central introductory sample from the Peter Fonda B-movie The Wild Angels.
The resulting track, "Loaded", became the band's first major hit, reaching number 16 on the UK Singles Chart.
This was followed by another single, "Come Together", which reached number 19.

The band entered the studio with Weatherall, Hugo Nicolson, The Orb and Jimmy Miller producing, and Martin Duffy now full-time on keyboards.
They released two more singles, "Higher Than The Sun" and "Don't Fight It, Feel It" which featured the lead vocals of Manchester singer Denise Johnson.
The album, Screamadelica, was released in late 1991 to positive reviews.
Ink Blot Magazine said that the album was "both of its time and timeless."
The album was also a commercial success, reaching number eight on the UK chart.
The album won the first Mercury Music Prize, beating Gillespie's former band The Jesus and Mary Chain.

The supporting tour kicked off in Amsterdam, and it included a performance at the Glastonbury festival before coming to an end in Sheffield.
Throughout the tour the band and their increasingly large entourage gained notoriety for their large narcotic intake.
Around this time, the band recorded the Dixie Narco EP.
Some of the tracks had a more American blues rock sound than previously, and displayed a P-Funk influence.
The band were first introduced to the acid house scene by McGee in 1988. They were at first sceptical; Gillespie said: "I always remember being quite fascinated by it but not quite getting it." The band developed a taste for it and began attending raves. The band met up with DJ Andrew Weatherall at a rave, and he was given a copy of "I'm Losing More Than I'll Ever Have", a track from Primal Scream, to remix for one of his shows. Weatherall added a drum loop from an Italian bootleg mix of Edie Brickell's "What I Am", a sample of Gillespie singing a line from Robert Johnson's "Terraplane Blues" and the central introductory sample from the Peter Fonda B-movie The Wild Angels. The resulting track, "Loaded", became the band's first major hit, reaching number 16 on the UK Singles Chart. This was followed by another single, "Come Together", which reached number 19.
The band entered the studio with Weatherall, Hugo Nicolson, The Orb and Jimmy Miller producing, and Martin Duffy now full-time on keyboards. They released two more singles, "Higher Than The Sun" and "Don't Fight It, Feel It" which featured the lead vocals of Manchester singer Denise Johnson. The album, Screamadelica, was released in late 1991 to positive reviews. Ink Blot Magazine said that the album was "both of its time and timeless." The album was also a commercial success, reaching number eight on the UK chart. The album won the first Mercury Music Prize, beating Gillespie's former band The Jesus and Mary Chain.
The supporting tour kicked off in Amsterdam, and it included a performance at the Glastonbury festival before coming to an end in Sheffield. Throughout the tour the band and their increasingly large entourage gained notoriety for their large narcotic intake. Around this time, the band recorded the Dixie Narco EP. Some of the tracks had a more American blues rock sound than previously, and displayed a P-Funk influence.
Primal Scream