Wapello is located at 41°10′47″N 91°11′18″W (41.179610, -91.188407).

According to the United States Census Bureau, the city has a total area of 1.34 square miles (3.47 km²), of which 1.29 square miles (3.34 km²) is land and 0.05 square miles (0.13 km²) is water.
Wapello is on the Iowa River.
Wapello is located at 41°10′47″N 91°11′18″W (41.179610, -91.188407).
According to the United States Census Bureau, the city has a total area of 1.34 square miles (3.47 km²), of which 1.29 square miles (3.34 km²) is land and 0.05 square miles (0.13 km²) is water. Wapello is on the Iowa River.
Wapello, Iowa