Saltsburg Historic District is a national historic district located at Saltsburg in Indiana County, Pennsylvania.
The district includes 118 contributing buildings, 1 contributing site, 1 contributing structure, and 15 contributing objects in the central business district and surrounding residential areas of Saltsburg.
The district includes notable examples of buildings in the Federal and Late Victorian styles.
Most of the buildings were built between the 1830s and 1880s.
Notable buildings include the William McIlwaine House and Store (1820–1829), Dr. James Crawford House (1830–1839), Dr. McFarland's Drug Store and Office (1840), Saltsburg Hotel (1870s), Western Pennsylvania Railroad Station (1864), Saltsburg Presbyterian Church (1874), Sons of Zebedee Evangelical Lutheran Church (1878), Altman Feed Mill (1893), First National Bank Building (1927), DeLisi Theater (1923).
The contributing site is former canal / railbed of the Western Pennsylvania Railroad and Lock #8, now occupied by Canal Park.
The contributing structure are the retaining walls of the railroad.
The contributing objects are canal markers.

It was listed on the National Register of Historic Places in 1992.
Saltsburg Historic District is a national historic district located at Saltsburg in Indiana County, Pennsylvania. The district includes 118 contributing buildings, 1 contributing site, 1 contributing structure, and 15 contributing objects in the central business district and surrounding residential areas of Saltsburg. The district includes notable examples of buildings in the Federal and Late Victorian styles. Most of the buildings were built between the 1830s and 1880s. Notable buildings include the William McIlwaine House and Store (1820–1829), Dr. James Crawford House (1830–1839), Dr. McFarland's Drug Store and Office (1840), Saltsburg Hotel (1870s), Western Pennsylvania Railroad Station (1864), Saltsburg Presbyterian Church (1874), Sons of Zebedee Evangelical Lutheran Church (1878), Altman Feed Mill (1893), First National Bank Building (1927), DeLisi Theater (1923). The contributing site is former canal / railbed of the Western Pennsylvania Railroad and Lock #8, now occupied by Canal Park. The contributing structure are the retaining walls of the railroad. The contributing objects are canal markers.
It was listed on the National Register of Historic Places in 1992.
Saltsburg Historic District