After Poland was invaded in September 1939, the town was briefly incorporated into the Byelorussian SSR as raion center in Belastok Region.
However, on 7 September 1940, Stalin transferred Druskininkai to Lithuania which in turn was annexed in August of that year and incorporated into the Soviet Union.
It was occupied by Nazi Germany on 23 June 1941 and was part of Bezirk Bialystok.
At this period, and as part of the "Final Solution" plan of the Nazis, the Jewish community of the town was wiped out.
Some of the Jews were sent to ghettos in near-by Kaunas, and the remainder murdered by the Nazis.

It was occupied again by Red Army on 14 July 1944 and passed to Lithuanian SSR.
In 1951, Druskininkai began to grow rapidly again and several huge sanatoriums and spa hospitals were opened.
The city became a famous resort, attracting around 400,000 visitors per year from all over the Soviet Union.
After Poland was invaded in September 1939, the town was briefly incorporated into the Byelorussian SSR as raion center in Belastok Region. However, on 7 September 1940, Stalin transferred Druskininkai to Lithuania which in turn was annexed in August of that year and incorporated into the Soviet Union. It was occupied by Nazi Germany on 23 June 1941 and was part of Bezirk Bialystok. At this period, and as part of the "Final Solution" plan of the Nazis, the Jewish community of the town was wiped out. Some of the Jews were sent to ghettos in near-by Kaunas, and the remainder murdered by the Nazis. 
It was occupied again by Red Army on 14 July 1944 and passed to Lithuanian SSR. In 1951, Druskininkai began to grow rapidly again and several huge sanatoriums and spa hospitals were opened. The city became a famous resort, attracting around 400,000 visitors per year from all over the Soviet Union.
Druskininkai