In the 1970s Mendini was one of the main personalities of the Radical design movement.
He became one of the founding members of the "Global Tools" collective, which was set up in 1973.
 In 1978 he joined the Studio Alchimia as a partner and there he worked with Ettore Sottsass and Michele De Lucchi.
Mendini created a Proust chair that combines existing designs and abstract forms with a new concept of Re-Design.
This chair proves that his experimental attempts are possible not only by experiment but also by realistic design logic.
In 1982 he co-founded Domus Academy, a private postgraduate design school in Milan.

As an architect, he designed several buildings; for example the Alessi residence in Omegna, Italy; the theater complex "Teatrino della Bicchieraia" in the Tuscan city of Arezzo; the Forum Museum of Omegna, a memorial tower in Hiroshima, Japan; the Groninger Museum in The Netherlands and the Arosa Casino in Switzerland.
Especially, The Groninger Museum is considered one of the most amazing postmodern buildings of the late 20th century, and was also selected as one of the “1001 Buildings You Must See Before You Die.”

His work in product design was influential in the sense that it pushed the boundaries of what products could be.
A notable example is his Lassú chair from 1974, a chair built on top of a pyramid structure, which forgoes conventional notions of function.
Mendini was addressing the domestic object as a conduit for spirituality, an idea reinforced by his ritualised burning of the chair, photographed for placement on the cover of Casabella in 1975.

As designer, the historical value of the RAMUN amuleto lamp designed in 2010 is the ring shape that accentuates the strengths of LED, which enhances lighting uniformity.
The use of a transparent material flaunts the mechanism of the lamp.
A mix of various colors in the minimalist structure, consisting of circles and straight lines without any spring or wire, inspires human sensibility.
Thanks to its beautiful design and superior performance, the lamp is permanently displayed at the Moderne der Pinakothek in Munich, Germany, The Chicago Athenaeum Museum of Architecture and Design, the Groninger Museum in Netherlands, the Design Museum Denmark, DDP in Korea and the Tsinghua University Art Museum in China.
In the 1970s Mendini was one of the main personalities of the Radical design movement. He became one of the founding members of the "Global Tools" collective, which was set up in 1973.  In 1978 he joined the Studio Alchimia as a partner and there he worked with Ettore Sottsass and Michele De Lucchi. Mendini created a Proust chair that combines existing designs and abstract forms with a new concept of Re-Design. This chair proves that his experimental attempts are possible not only by experiment but also by realistic design logic. In 1982 he co-founded Domus Academy, a private postgraduate design school in Milan. 
As an architect, he designed several buildings; for example the Alessi residence in Omegna, Italy; the theater complex "Teatrino della Bicchieraia" in the Tuscan city of Arezzo; the Forum Museum of Omegna, a memorial tower in Hiroshima, Japan; the Groninger Museum in The Netherlands and the Arosa Casino in Switzerland. Especially, The Groninger Museum is considered one of the most amazing postmodern buildings of the late 20th century, and was also selected as one of the “1001 Buildings You Must See Before You Die.” 
His work in product design was influential in the sense that it pushed the boundaries of what products could be. A notable example is his Lassú chair from 1974, a chair built on top of a pyramid structure, which forgoes conventional notions of function. Mendini was addressing the domestic object as a conduit for spirituality, an idea reinforced by his ritualised burning of the chair, photographed for placement on the cover of Casabella in 1975.
As designer, the historical value of the RAMUN amuleto lamp designed in 2010 is the ring shape that accentuates the strengths of LED, which enhances lighting uniformity. The use of a transparent material flaunts the mechanism of the lamp. A mix of various colors in the minimalist structure, consisting of circles and straight lines without any spring or wire, inspires human sensibility. Thanks to its beautiful design and superior performance, the lamp is permanently displayed at the Moderne der Pinakothek in Munich, Germany, The Chicago Athenaeum Museum of Architecture and Design, the Groninger Museum in Netherlands, the Design Museum Denmark, DDP in Korea and the Tsinghua University Art Museum in China.
Alessandro Mendini