Taking progestin in addition to an estrogen patch should be considered for women who have not undergone a hysterectomy to regulate the thickness of the endometrial lining  and reduce the risk of endometrial cancer.
Hysterectomized women rarely need progestin, however it may be considered if a history of endometriosis exists.
There are different types of delivery systems of progestin that can be used in addition to an estrogen patch, including pills, injections, and patches.

Research has suggested that estrogen plus progestin therapy may increase the risk of heart attacks, stroke, breast cancer, blot clots, and dementia in postmenopausal women.
Taking the lowest effective dose of both estrogen and progestin may reduce risks.
Taking progestin in addition to an estrogen patch should be considered for women who have not undergone a hysterectomy to regulate the thickness of the endometrial lining  and reduce the risk of endometrial cancer. Hysterectomized women rarely need progestin, however it may be considered if a history of endometriosis exists. There are different types of delivery systems of progestin that can be used in addition to an estrogen patch, including pills, injections, and patches.
Research has suggested that estrogen plus progestin therapy may increase the risk of heart attacks, stroke, breast cancer, blot clots, and dementia in postmenopausal women. Taking the lowest effective dose of both estrogen and progestin may reduce risks.
Estrogen patch