With her first husband, Henry Seymour, Lord Beauchamp (c. 1626–1654), she had two children:
William Seymour, 3rd Duke of Somerset (d. 1671)
Lady Elizabeth Seymour (c. 1655–1697) married Thomas Bruce, 2nd Earl of Ailesbury
With her second husband, Henry Somerset, 1st Duke of Beaufort (1629–1700), she had:
Henry Somerset, Lord Herbert (bef.
1660), who died as infant
Charles Somerset, Marquess of Worcester (1660-1698), who had a military and political career.

unknown daughter Somerset (b. bef.
1663)
Lady Mary Somerset (1664-1733), who married James Butler, 2nd Duke of Ormonde
Lady Henrietta Somerset (c.1670-1715), who married firstly, Lord Ilbracken, son of Henry O'Brien, 7th Earl of Thomond, and secondly, Henry Howard, 6th Earl of Suffolk
Lord Arthur Somerset (1671-1743), who married Mary Russell in 1695, daughter of William Russell, 1st and last Bt.,
and Hesther Rouse, daughter of Sir Thomas Rouse, 1st Bt. (
1608-1676).
Their daughter, Mary Somerset, was the grandmother of Sir Charles William Rouse Boughton, 1st and 9th Bt..
Lady Anne Somerset (1673–1763), who married Thomas Coventry, 2nd Earl of Coventry
Mary was widowed in 1700 and later died on 7 January 1715 in Chelsea, London, England at the age of 84.
She was buried at St Michael and All Angels Church in Badminton, Gloucestershire.
With her first husband, Henry Seymour, Lord Beauchamp (c. 1626–1654), she had two children:
William Seymour, 3rd Duke of Somerset (d. 1671)
Lady Elizabeth Seymour (c. 1655–1697) married Thomas Bruce, 2nd Earl of Ailesbury
With her second husband, Henry Somerset, 1st Duke of Beaufort (1629–1700), she had:
Henry Somerset, Lord Herbert (bef. 1660), who died as infant
Charles Somerset, Marquess of Worcester (1660-1698), who had a military and political career.
unknown daughter Somerset (b. bef. 1663)
Lady Mary Somerset (1664-1733), who married James Butler, 2nd Duke of Ormonde
Lady Henrietta Somerset (c.1670-1715), who married firstly, Lord Ilbracken, son of Henry O'Brien, 7th Earl of Thomond, and secondly, Henry Howard, 6th Earl of Suffolk
Lord Arthur Somerset (1671-1743), who married Mary Russell in 1695, daughter of William Russell, 1st and last Bt., and Hesther Rouse, daughter of Sir Thomas Rouse, 1st Bt. (1608-1676). Their daughter, Mary Somerset, was the grandmother of Sir Charles William Rouse Boughton, 1st and 9th Bt..
Lady Anne Somerset (1673–1763), who married Thomas Coventry, 2nd Earl of Coventry
Mary was widowed in 1700 and later died on 7 January 1715 in Chelsea, London, England at the age of 84. She was buried at St Michael and All Angels Church in Badminton, Gloucestershire.
Mary Somerset, Duchess of Beaufort (1630–1715)