Application of benzoyl peroxide to the skin may result in redness, burning, and irritation.
This side effect is dose-dependent.

Because of these possible side effects, it is recommended to start with a low concentration and build up as appropriate, as the skin gradually develops tolerance to the medication.
Skin sensitivity typically resolves after a few weeks of continuous use.
Irritation can also be reduced by avoiding harsh facial cleansers and wearing sunscreen prior to sun exposure.

One in 500 people  experience hypersensitivity to BPO and liable to suffer burning, itching, crusting, and possibly swelling.
 About one-third of people experience phototoxicity under exposure to ultraviolet (UVB) light.

The safety of BPO use during pregnancy is unclear.
Application of benzoyl peroxide to the skin may result in redness, burning, and irritation. This side effect is dose-dependent.
Because of these possible side effects, it is recommended to start with a low concentration and build up as appropriate, as the skin gradually develops tolerance to the medication. Skin sensitivity typically resolves after a few weeks of continuous use. Irritation can also be reduced by avoiding harsh facial cleansers and wearing sunscreen prior to sun exposure.
One in 500 people  experience hypersensitivity to BPO and liable to suffer burning, itching, crusting, and possibly swelling.  About one-third of people experience phototoxicity under exposure to ultraviolet (UVB) light.
The safety of BPO use during pregnancy is unclear.
Benzoyl peroxide