It was in the hall, during its inauguration at the Inter-American Conference it hosted, that "three thousand leaders and delegates" of the Americas signed a historical resolution declaring Communism a threat to world peace.
Conversely, in his first visit to Venezuela, in 1959 after the success of the communist Cuban Revolution, Fidel Castro spoke at the hall.

There have also been famous artistic performances.
Leonard Bernstein performed at the hall in 1957, saying that it "was the best [hall] in which I conducted in South America.
After the concert I told the reporters that the sound is excellent on stage.
I would like to be able to take that part of the hall back to New York for the Philharmonic".
Montserrat Caballe has sung in the hall, and Pablo Neruda recited his poetry in it.

The theatre company "Palo de Agua", operated by Michel Hausmann, was based in the hall until at least 2013.
Hausmann, from a family with a history of opposition to Venezuelan presidents Hugo Chávez and Nicolás Maduro, explained that they were not allowed to perform in any of Caracas' main theatres because of the restriction and censorship of artistic expression in Venezuela, describing the hall as "one of the last 'free spaces' to do theatre" since the government took control of all other theatres that seat more than 500 people.
One of the company's productions of Jesus Christ Superstar in the hall, on March 7, 2010, was attacked as a political campaign of intimidation against the group by masked assailants with tear gas before the show, harming the actors.

Graduation ceremonies for both UCV and other universities are held in the hall, though to some controversy, with citizens and students saying that the use of the hall should be limited to performances and for the traditional ceremony of UCV students only.
In 2018, one student political party described the leasing of the hall to another university "commercialisation" of the heritage site.

The hall is also used for student addresses, and in February 2019 the hall was used by then-UCV student president Rafaela Requesens when rallying students to participate in protests during the 2019 Venezuelan presidential crisis.
She opened her speech by describing the hall, saying "This is a space of ideas, of knowledge, of plurality of thought, of freedom, of democracy, of justice.
Young people always give a message of hope, today of reflection."
It was in the hall, during its inauguration at the Inter-American Conference it hosted, that "three thousand leaders and delegates" of the Americas signed a historical resolution declaring Communism a threat to world peace. Conversely, in his first visit to Venezuela, in 1959 after the success of the communist Cuban Revolution, Fidel Castro spoke at the hall.
There have also been famous artistic performances. Leonard Bernstein performed at the hall in 1957, saying that it "was the best [hall] in which I conducted in South America. After the concert I told the reporters that the sound is excellent on stage. I would like to be able to take that part of the hall back to New York for the Philharmonic". Montserrat Caballe has sung in the hall, and Pablo Neruda recited his poetry in it.
The theatre company "Palo de Agua", operated by Michel Hausmann, was based in the hall until at least 2013. Hausmann, from a family with a history of opposition to Venezuelan presidents Hugo Chávez and Nicolás Maduro, explained that they were not allowed to perform in any of Caracas' main theatres because of the restriction and censorship of artistic expression in Venezuela, describing the hall as "one of the last 'free spaces' to do theatre" since the government took control of all other theatres that seat more than 500 people. One of the company's productions of Jesus Christ Superstar in the hall, on March 7, 2010, was attacked as a political campaign of intimidation against the group by masked assailants with tear gas before the show, harming the actors.
Graduation ceremonies for both UCV and other universities are held in the hall, though to some controversy, with citizens and students saying that the use of the hall should be limited to performances and for the traditional ceremony of UCV students only. In 2018, one student political party described the leasing of the hall to another university "commercialisation" of the heritage site.
The hall is also used for student addresses, and in February 2019 the hall was used by then-UCV student president Rafaela Requesens when rallying students to participate in protests during the 2019 Venezuelan presidential crisis. She opened her speech by describing the hall, saying "This is a space of ideas, of knowledge, of plurality of thought, of freedom, of democracy, of justice. Young people always give a message of hope, today of reflection."
Aula Magna (Central University of Venezuela)