On October 30, 2018, the Broncos traded Thomas and a seventh round pick in the 2019 NFL Draft to the Houston Texans for a fourth and seventh round pick in the 2019 draft.

In his debut with the Texans, he had three receptions for 61 receiving yards in the 19–17 victory over the Broncos, his former team.
In Week 12, against the Tennessee Titans, he recorded four receptions for 38 receiving yards and two receiving touchdowns in the 34–17 victory.
During Week 16, Thomas was carted off the field in the second half of a 32–30 loss to the Philadelphia Eagles with an apparent Achilles injury.
It was revealed that he suffered a torn Achilles and was placed on injured reserve on December 24, 2018.

In the 2018 season, combined with his time with the Broncos and Texans, Thomas recorded 59 receptions for 677 yards and five touchdowns.

On February 12, 2019, Thomas was released by the Texans.
On October 30, 2018, the Broncos traded Thomas and a seventh round pick in the 2019 NFL Draft to the Houston Texans for a fourth and seventh round pick in the 2019 draft.
In his debut with the Texans, he had three receptions for 61 receiving yards in the 19–17 victory over the Broncos, his former team. In Week 12, against the Tennessee Titans, he recorded four receptions for 38 receiving yards and two receiving touchdowns in the 34–17 victory. During Week 16, Thomas was carted off the field in the second half of a 32–30 loss to the Philadelphia Eagles with an apparent Achilles injury. It was revealed that he suffered a torn Achilles and was placed on injured reserve on December 24, 2018.
In the 2018 season, combined with his time with the Broncos and Texans, Thomas recorded 59 receptions for 677 yards and five touchdowns.
On February 12, 2019, Thomas was released by the Texans.
Demaryius Thomas