In January 2006, 25 artists including Paparizou formed the group Simmeteho Energa, and recorded a charity single "Eho Ti Dinami" in support of the Greek Cancer Society.
It was released as a CD single.
The two-disc album contained previously released material and live recordings from her MAD Secret Concert held in December 2005, and formed the first edition of the series.

On 12 April, Paparizou released her second album, Iparhi Logos in Greece where it had a good critical reception.
While promoting the album, Paparizou performed the title track at the Arion Music Awards.
The album included three hit singles; "Iparhi Logos", "Gigolo" and "An Ihes Erthi Pio Noris".
It topped the Greek Albums Chart for a number of weeks and was certified platinum by IFPI Greece after seven months, with shipments of 30,000 copies.
It also reached number one in Cyprus and was certified Platinum there, with shipments of 6,000 copies.
A cover of Celine Dion's "Just Walk Away" was released as a promo single, with the Greek version of "Mambo!"
included.
Paparizou won MAD VMAs for Best Video by a Female Artist ("Gigolo") and Best-Dressed Artist in a Video ("An Ihes Erthi Pio Noris"), from five nominations and opened the show singing "Aquarius/Let the Sunshine In" and "Min Fevgeis".

The album was also nominated for two Cyprus Music Awards in 2007, where she also performed.
The album was reissued in February 2007 as Iparhi Logos: Platinum Edition to include Paparizou's number one hit "Mazi Sou", one of two songs she sang for the soundtrack of the television series of the same name, "Fos" from the Barbie kai I Dodeka Vasilopoules soundtrack released in 2006, and her newest hit single, a cover of Voula Georgouti's rebetiko "Min Fevgeis", which reached number two.
Prior to the reissue, the singles were also released on the EP single Fos, which reached number one on the Greek Top 50 Singles Chart and was certified Gold, making it her fourth consecutive number-one hit on that chart.
On 20 May 2006, Paparizou opened the Eurovision Song Contest 2006 in Athens with "My Number One" and later performed "Mambo!",
but ERT ran commercials during the performance so a number of countries missed the song.
Paparizou's song "Heroes" was the official song of, and performed at the 2006 European Athletics Championships in Gothenburg.
The single was released in Sweden and Finland, becoming her second number-one hit in the former.

Following Eurovision, Paparizou wanted to start an international career, Her debut English-language album The Game of Love was released on 25 October 2006.
By April 2007, it had been released in 14 countries in Europe and in South Africa.
In Greece and Cyprus, the album peaked at number one and received Platinum certifications.
Because it was considered a "foreign" release, the album was only eligible to chart on the Greek Foreign Albums Chart, which it topped.
It also topped the mixed Greek Albums Chart, and was certified platinum by IFPI Greece after 11 weeks on the chart in January 2007, with shipments of 15,000 copies. "
Teardrops" was released as the first Greek single from the album, and peaked at number one in Greece.
The album managed to peak at #18 in Sweden too. "
Mambo!"
charted in Sweden, peaked at number 5, helped by a new video that was targeted towards a broader audience.
The single was certified Gold in Sweden.
Although Paparizou was expected to promote the album abroad that winter, she chose to perform alongside Paschalis Terzis at Iera Odos from 27 October.

In early 2007, Paparizou became the spokesperson for her previous sponsor, Nokia Greece, and released the song "Ola Einai Mousiki" in October 2007 for promotion.
She collaborated with retailer Plaisio and released a limited edition MP4 player called "MP4 Total Helena" (2GB) by Turbo-X, which contained a special compilation and music videos, which were also released as "TH4" MP4 in 2008 along with her new album material and exclusive content.
She released a cover of Blind Melon's "3 Is a Magic Number" in Sweden as part of a television advertisement for a mobile phone company; it
In January 2006, 25 artists including Paparizou formed the group Simmeteho Energa, and recorded a charity single "Eho Ti Dinami" in support of the Greek Cancer Society. It was released as a CD single. The two-disc album contained previously released material and live recordings from her MAD Secret Concert held in December 2005, and formed the first edition of the series.
On 12 April, Paparizou released her second album, Iparhi Logos in Greece where it had a good critical reception. While promoting the album, Paparizou performed the title track at the Arion Music Awards. The album included three hit singles; "Iparhi Logos", "Gigolo" and "An Ihes Erthi Pio Noris". It topped the Greek Albums Chart for a number of weeks and was certified platinum by IFPI Greece after seven months, with shipments of 30,000 copies. It also reached number one in Cyprus and was certified Platinum there, with shipments of 6,000 copies. A cover of Celine Dion's "Just Walk Away" was released as a promo single, with the Greek version of "Mambo!" included. Paparizou won MAD VMAs for Best Video by a Female Artist ("Gigolo") and Best-Dressed Artist in a Video ("An Ihes Erthi Pio Noris"), from five nominations and opened the show singing "Aquarius/Let the Sunshine In" and "Min Fevgeis".
The album was also nominated for two Cyprus Music Awards in 2007, where she also performed. The album was reissued in February 2007 as Iparhi Logos: Platinum Edition to include Paparizou's number one hit "Mazi Sou", one of two songs she sang for the soundtrack of the television series of the same name, "Fos" from the Barbie kai I Dodeka Vasilopoules soundtrack released in 2006, and her newest hit single, a cover of Voula Georgouti's rebetiko "Min Fevgeis", which reached number two. Prior to the reissue, the singles were also released on the EP single Fos, which reached number one on the Greek Top 50 Singles Chart and was certified Gold, making it her fourth consecutive number-one hit on that chart. On 20 May 2006, Paparizou opened the Eurovision Song Contest 2006 in Athens with "My Number One" and later performed "Mambo!", but ERT ran commercials during the performance so a number of countries missed the song. Paparizou's song "Heroes" was the official song of, and performed at the 2006 European Athletics Championships in Gothenburg. The single was released in Sweden and Finland, becoming her second number-one hit in the former.
Following Eurovision, Paparizou wanted to start an international career, Her debut English-language album The Game of Love was released on 25 October 2006. By April 2007, it had been released in 14 countries in Europe and in South Africa. In Greece and Cyprus, the album peaked at number one and received Platinum certifications. Because it was considered a "foreign" release, the album was only eligible to chart on the Greek Foreign Albums Chart, which it topped. It also topped the mixed Greek Albums Chart, and was certified platinum by IFPI Greece after 11 weeks on the chart in January 2007, with shipments of 15,000 copies. "Teardrops" was released as the first Greek single from the album, and peaked at number one in Greece. The album managed to peak at #18 in Sweden too. "Mambo!" charted in Sweden, peaked at number 5, helped by a new video that was targeted towards a broader audience. The single was certified Gold in Sweden. Although Paparizou was expected to promote the album abroad that winter, she chose to perform alongside Paschalis Terzis at Iera Odos from 27 October.
In early 2007, Paparizou became the spokesperson for her previous sponsor, Nokia Greece, and released the song "Ola Einai Mousiki" in October 2007 for promotion. She collaborated with retailer Plaisio and released a limited edition MP4 player called "MP4 Total Helena" (2GB) by Turbo-X, which contained a special compilation and music videos, which were also released as "TH4" MP4 in 2008 along with her new album material and exclusive content. She released a cover of Blind Melon's "3 Is a Magic Number" in Sweden as part of a television advertisement for a mobile phone company; it
Helena Paparizou