The monastery was established after the Christianization of Bulgaria in the 9th century during the reign of Boris I (r. 852–889).
It was destroyed in 971 by the Byzantines when they seized Preslav in the aftermath of the Sviatoslav's invasion of Bulgaria and was repeatedly plundered and devastated by the Pechenegs and the Cumans in the 11th and 12th centuries during the Byzantine rule of Bulgaria.
According to researchers, the monastery was an important literary centre during the First Bulgarian Empire and of the most important sites of the Preslav Literary School, there the disciples of the Saints Cyril and Methodius, Clement of Ohrid and Naum of Preslav had worked.

The Patleina Monastery was also an artistic-production centre.
During the excavations of the site carried out between 1909 and 1914, a 10th century mosaic ceramic icon of Saint Theodore Stratelates was discovered.
It has since become one of the symbols of the medieval Bulgarian heritage and is now kept at the National Archaeological Museum.
Other artefacts dates from the 9th and 10th centuries excavated at the site include ceramic icons of Saint Philip and Mark the Evangelist, crucifixes, a bronze matrix of an icon of blessing Christ sitting on a throne.
The monastery was declared a monument of culture.

In the 1940s a new monetary was constructed on the slope over the medieval site.
However, it was never consecrated as it was nationalised after 1944 by the new Socialist authorities and converted into a vacation home.
The monastery was established after the Christianization of Bulgaria in the 9th century during the reign of Boris I (r. 852–889). It was destroyed in 971 by the Byzantines when they seized Preslav in the aftermath of the Sviatoslav's invasion of Bulgaria and was repeatedly plundered and devastated by the Pechenegs and the Cumans in the 11th and 12th centuries during the Byzantine rule of Bulgaria. According to researchers, the monastery was an important literary centre during the First Bulgarian Empire and of the most important sites of the Preslav Literary School, there the disciples of the Saints Cyril and Methodius, Clement of Ohrid and Naum of Preslav had worked.
The Patleina Monastery was also an artistic-production centre. During the excavations of the site carried out between 1909 and 1914, a 10th century mosaic ceramic icon of Saint Theodore Stratelates was discovered. It has since become one of the symbols of the medieval Bulgarian heritage and is now kept at the National Archaeological Museum. Other artefacts dates from the 9th and 10th centuries excavated at the site include ceramic icons of Saint Philip and Mark the Evangelist, crucifixes, a bronze matrix of an icon of blessing Christ sitting on a throne. The monastery was declared a monument of culture.
In the 1940s a new monetary was constructed on the slope over the medieval site. However, it was never consecrated as it was nationalised after 1944 by the new Socialist authorities and converted into a vacation home.
Patleina Monastery