Wallace was raised in the Calvinist branch of Protestant Christianity, but showed an interest in other religious teachings during his life.
He was deeply interested in religion from a young age, reading works by authors like Ralph Waldo Emerson, Ralph Waldo Trine, and William James, whose The Varieties of Religious Experience had a particularly strong impact on Wallace.
After his grandfather's death in 1916, he left the Presbyterian Church and became increasingly interested in mysticism.
He later said, "I know I am often called a mystic, and in the years following my leaving the United Presbyterian Church I was probably a practical mystic…  I'd say I was a mystic in the sense that George Washington Carver was – who believed God was in everything and therefore, if you went to God, you could find the answers".
Wallace began regularly attending meetings of the pantheistic Theosophical Society, and, in 1925, he helped organize the Des Moines parish of the Liberal Catholic Church.
Wallace left the Liberal Catholic Church in 1930 and joined the Episcopal Church, but he continued to be interested in various mystic groups and individuals.

Among those who Wallace corresponded with were author George William Russell, astrologer L. Edward Johndro, and Edward Roos, who took on the persona of a Native American medicine man.
In the early 1930s, Wallace began corresponding with Nicholas Roerich, a prominent Russian émigré, artist, peace activist, and Theosophist.
With Wallace's support, Roerich was appointed to lead a federal expedition to the Gobi Desert to collect drought-resistant grasses.
Roerich's expedition ended in a public fiasco, and Roerich fled to India after the Internal Revenue Service launched a tax investigation.

The letters that Wallace wrote to Roerich from 1933 to 1934 were eventually acquired by Republican newspaper publisher Paul Block.
 The Republicans threatened to reveal to the public what they characterized as Wallace's bizarre religious beliefs before the November 1940 elections but were deterred when the Democrats countered by threatening to release information about Republican candidate Wendell Willkie's rumored extramarital affair with the writer Irita Van Doren.
The contents of the letters did become public seven years later, in the winter of 1947, when right-wing columnist Westbrook Pegler published what were purported to be extracts from them as evidence that Wallace was a "messianic fumbler", and "off-center mentally".
During the 1948 campaign Pegler and other hostile reporters, including H. L. Mencken, aggressively confronted Wallace on the subject at a public meeting in Philadelphia in July.
Wallace declined to comment, accusing the reporters of being Pegler's stooges.
Many press outlets were critical of Wallace's association with Roerich; one newspaper mockingly wrote that if Wallace became president "we shall get in tune with the Infinite, vibrate in the correct plane, outstare the Evil Eye, reform the witches, overcome all malicious spells and ascend the high road to health and happiness".

Henry Wallace reportedly dabbled in Zoroastrianism and Buddhism.
Wallace was raised in the Calvinist branch of Protestant Christianity, but showed an interest in other religious teachings during his life. He was deeply interested in religion from a young age, reading works by authors like Ralph Waldo Emerson, Ralph Waldo Trine, and William James, whose The Varieties of Religious Experience had a particularly strong impact on Wallace. After his grandfather's death in 1916, he left the Presbyterian Church and became increasingly interested in mysticism. He later said, "I know I am often called a mystic, and in the years following my leaving the United Presbyterian Church I was probably a practical mystic…  I'd say I was a mystic in the sense that George Washington Carver was – who believed God was in everything and therefore, if you went to God, you could find the answers". Wallace began regularly attending meetings of the pantheistic Theosophical Society, and, in 1925, he helped organize the Des Moines parish of the Liberal Catholic Church. Wallace left the Liberal Catholic Church in 1930 and joined the Episcopal Church, but he continued to be interested in various mystic groups and individuals.
Among those who Wallace corresponded with were author George William Russell, astrologer L. Edward Johndro, and Edward Roos, who took on the persona of a Native American medicine man. In the early 1930s, Wallace began corresponding with Nicholas Roerich, a prominent Russian émigré, artist, peace activist, and Theosophist. With Wallace's support, Roerich was appointed to lead a federal expedition to the Gobi Desert to collect drought-resistant grasses. Roerich's expedition ended in a public fiasco, and Roerich fled to India after the Internal Revenue Service launched a tax investigation.
The letters that Wallace wrote to Roerich from 1933 to 1934 were eventually acquired by Republican newspaper publisher Paul Block.  The Republicans threatened to reveal to the public what they characterized as Wallace's bizarre religious beliefs before the November 1940 elections but were deterred when the Democrats countered by threatening to release information about Republican candidate Wendell Willkie's rumored extramarital affair with the writer Irita Van Doren. The contents of the letters did become public seven years later, in the winter of 1947, when right-wing columnist Westbrook Pegler published what were purported to be extracts from them as evidence that Wallace was a "messianic fumbler", and "off-center mentally". During the 1948 campaign Pegler and other hostile reporters, including H. L. Mencken, aggressively confronted Wallace on the subject at a public meeting in Philadelphia in July. Wallace declined to comment, accusing the reporters of being Pegler's stooges. Many press outlets were critical of Wallace's association with Roerich; one newspaper mockingly wrote that if Wallace became president "we shall get in tune with the Infinite, vibrate in the correct plane, outstare the Evil Eye, reform the witches, overcome all malicious spells and ascend the high road to health and happiness".
Henry Wallace reportedly dabbled in Zoroastrianism and Buddhism.
Henry A. Wallace