Mills was appointed in 1927, by the President Calvin Coolidge as the Undersecretary of the Treasury, serving under Secretary Andrew W. Mellon.

In 1932, Mills was appointed by President Herbert Hoover as Secretary of the Treasury.
 While Secretary, Mills acted as an adviser to President Hoover and actively campaigned for Hoover's reelection  in 1932, traveling to Detroit, St. Louis, Los Angeles, San Francisco, Chicago, and Minneapolis on his behalf.
 Hoover's opponent was then Governor of New York, Franklin D. Roosevelt, a Democrat who was Mills's college friend and life-long neighbor.
 He remained in office until March 3, 1933.
Mills was appointed in 1927, by the President Calvin Coolidge as the Undersecretary of the Treasury, serving under Secretary Andrew W. Mellon.
In 1932, Mills was appointed by President Herbert Hoover as Secretary of the Treasury.  While Secretary, Mills acted as an adviser to President Hoover and actively campaigned for Hoover's reelection  in 1932, traveling to Detroit, St. Louis, Los Angeles, San Francisco, Chicago, and Minneapolis on his behalf.  Hoover's opponent was then Governor of New York, Franklin D. Roosevelt, a Democrat who was Mills's college friend and life-long neighbor.  He remained in office until March 3, 1933.
Ogden L. Mills