Historically, Wounded Knee is generally considered to be the end of the collective multi-century series of conflicts between colonial and U.S. forces and American Indians, known collectively as the Indian Wars.
It was not however the last armed conflict between Native Americans and the United States.

The Drexel Mission Fight was an armed confrontation between Lakota warriors and the United States Army that took place on the Pine Ridge Indian Reservation on December 30, 1890, the day following Wounded Knee.
The fight occurred on White Clay Creek approximately 15 miles north of Pine Ridge, where Lakota fleeing from the continued hostile situation surrounding the massacre at Wounded Knee had set up camp.

Company K of the 7th Cavalry—the unit involved at Wounded Knee—was sent to force the Lakotas to return to the areas they were assigned on their respective reservations.
Some of the "hostiles" were Brulé Lakota from the Rosebud Indian Reservation.
Company K was pinned down in a valley by the combined Lakota forces and had to be rescued by the 9th Cavalry, an African American regiment nicknamed the "Buffalo Soldiers".

Among the Lakota warriors was a young Brulé from Rosebud named Plenty Horses, who had recently returned from five years at the Carlisle Indian School in Pennsylvania.
A week after this fight, Plenty Horses shot and killed army lieutenant Edward W. Casey, commandant of the Cheyenne Scouts (Troop L, 8th Cavalry).
The testimony introduced at the trial of Plenty Horses and his subsequent acquittal also helped abrogate the legal culpability of the U.S. Army for the deaths at Wounded Knee.
Historically, Wounded Knee is generally considered to be the end of the collective multi-century series of conflicts between colonial and U.S. forces and American Indians, known collectively as the Indian Wars. It was not however the last armed conflict between Native Americans and the United States.
The Drexel Mission Fight was an armed confrontation between Lakota warriors and the United States Army that took place on the Pine Ridge Indian Reservation on December 30, 1890, the day following Wounded Knee. The fight occurred on White Clay Creek approximately 15 miles north of Pine Ridge, where Lakota fleeing from the continued hostile situation surrounding the massacre at Wounded Knee had set up camp.
Company K of the 7th Cavalry—the unit involved at Wounded Knee—was sent to force the Lakotas to return to the areas they were assigned on their respective reservations. Some of the "hostiles" were Brulé Lakota from the Rosebud Indian Reservation. Company K was pinned down in a valley by the combined Lakota forces and had to be rescued by the 9th Cavalry, an African American regiment nicknamed the "Buffalo Soldiers".
Among the Lakota warriors was a young Brulé from Rosebud named Plenty Horses, who had recently returned from five years at the Carlisle Indian School in Pennsylvania. A week after this fight, Plenty Horses shot and killed army lieutenant Edward W. Casey, commandant of the Cheyenne Scouts (Troop L, 8th Cavalry). The testimony introduced at the trial of Plenty Horses and his subsequent acquittal also helped abrogate the legal culpability of the U.S. Army for the deaths at Wounded Knee.
Wounded Knee Massacre