Bradley Beesley directed a 2005 film about Coyne and the Flaming Lips, The Fearless Freaks, which features much footage of Coyne's early life, as well as his narration about his experiences in the band.

In 2003, Coyne provided vocals on "The Golden Path" by The Chemical Brothers.
 This track was released on the Singles 93-03 album (CD1, Track 13).

In 2005, Coyne recorded "Marching the Hate Machines (Into the Sun)" with the electronic-duo Thievery Corporation on their album The Cosmic Game.

On May 24, 2006, a video of Coyne was shown at the graduation ceremony at his old high school, the Classen School of Advanced Studies in Oklahoma City, Oklahoma.
In the video he spoke of not being a high school graduate, working at Long John Silver's, selling marijuana out of his apartment, and the value of life experience.

In 2006, Coyne appeared in a Swedish music program called 'Musikministeriet' ('The Ministry of Music').
He was featured in every episode, beginning and ending each one with a few eloquent words about that particular episode's theme, and his opinions about it.

On January 1, 2007, Coyne appeared in Pasadena, California's annual Rose Parade on the "Oklahoma Rising" float with members of the Flaming Lips, and other celebrities who claim Oklahoma as their native state, including astronaut John Herrington, 2006 Miss America Jennifer Berry, as well as the creator of "Desperate Housewives", Marc Cherry.
It was the state's centennial birthday.

Coyne and The Flaming Lips guest starred in an episode of the television show Charmed.

Coyne and The Flaming Lips appeared on an episode of Beverly Hills, 90210, playing at the Peach Pit.
They sometimes show the clip at live concerts.

Coyne sings on the opening track, "Revenge", of Danger Mouse and Sparklehorse's album with David Lynch, "Dark Night of the Soul".

Coyne sings on the track Colossal Gray Sunshine of Faultline's album Your Love Means Everything.

Coyne contributed several tracks to Kesha's second album, Warrior, including tracks titled "You Control My Heart" and "Past Life."
They also worked on Lipsha.

On August 16, 2012, Coyne appeared on The Colbert Report for an interview by Stephen Colbert and a performance with the Flaming Lips on the deck of the USS Intrepid as part of "Stephest Colbchella '012: Rocktaugustfest".

On March 12, 2013, Coyne appeared on a Virgin Mobile advertisement.
In the commercial Coyne attempts to brainwash the viewer into switching mobile phone plans.

Coyne appears on the track The Perfect Life on Moby's album Innocents released in October 2013.

Coyne wrote and illustrated the comic book "The Sun is Sick", which was published in April 2013.
Bradley Beesley directed a 2005 film about Coyne and the Flaming Lips, The Fearless Freaks, which features much footage of Coyne's early life, as well as his narration about his experiences in the band.
In 2003, Coyne provided vocals on "The Golden Path" by The Chemical Brothers.  This track was released on the Singles 93-03 album (CD1, Track 13).
In 2005, Coyne recorded "Marching the Hate Machines (Into the Sun)" with the electronic-duo Thievery Corporation on their album The Cosmic Game.
On May 24, 2006, a video of Coyne was shown at the graduation ceremony at his old high school, the Classen School of Advanced Studies in Oklahoma City, Oklahoma. In the video he spoke of not being a high school graduate, working at Long John Silver's, selling marijuana out of his apartment, and the value of life experience.
In 2006, Coyne appeared in a Swedish music program called 'Musikministeriet' ('The Ministry of Music'). He was featured in every episode, beginning and ending each one with a few eloquent words about that particular episode's theme, and his opinions about it.
On January 1, 2007, Coyne appeared in Pasadena, California's annual Rose Parade on the "Oklahoma Rising" float with members of the Flaming Lips, and other celebrities who claim Oklahoma as their native state, including astronaut John Herrington, 2006 Miss America Jennifer Berry, as well as the creator of "Desperate Housewives", Marc Cherry. It was the state's centennial birthday.
Coyne and The Flaming Lips guest starred in an episode of the television show Charmed.
Coyne and The Flaming Lips appeared on an episode of Beverly Hills, 90210, playing at the Peach Pit. They sometimes show the clip at live concerts.
Coyne sings on the opening track, "Revenge", of Danger Mouse and Sparklehorse's album with David Lynch, "Dark Night of the Soul".
Coyne sings on the track Colossal Gray Sunshine of Faultline's album Your Love Means Everything.
Coyne contributed several tracks to Kesha's second album, Warrior, including tracks titled "You Control My Heart" and "Past Life." They also worked on Lipsha.
On August 16, 2012, Coyne appeared on The Colbert Report for an interview by Stephen Colbert and a performance with the Flaming Lips on the deck of the USS Intrepid as part of "Stephest Colbchella '012: Rocktaugustfest".
On March 12, 2013, Coyne appeared on a Virgin Mobile advertisement. In the commercial Coyne attempts to brainwash the viewer into switching mobile phone plans.
Coyne appears on the track The Perfect Life on Moby's album Innocents released in October 2013.
Coyne wrote and illustrated the comic book "The Sun is Sick", which was published in April 2013.
Wayne Coyne