Undergoing metamorphosis requires a tremendous amount of change for the fly, such as cell death.
While it is commonly believed that programmed cell death and apoptosis are the same, they are not always so.
At the beginning of metamorphosis during the larvae stage, salivary gland cells of Calliphora vomitoria larvae are self-programmed to destroy.
After enough feeding, the larvae come to rest and an initial protein synthesis stage surges, culminating in the production of high amounts of protein.
This occurs from day 1 to about day 8.
Then, on day 9, cell death of salivary gland cells occurs.
This pattern of synthesis and destruction is not to be confused with apoptosis, as no DNA degeneration is seen and cells are shown to vacuolate and swell (compared to condense and shrink in the case of apoptosis).
Instead, selective expression and DNA synthesis is seen to support programmed cell death (of salivary gland cells).
Undergoing metamorphosis requires a tremendous amount of change for the fly, such as cell death. While it is commonly believed that programmed cell death and apoptosis are the same, they are not always so. At the beginning of metamorphosis during the larvae stage, salivary gland cells of Calliphora vomitoria larvae are self-programmed to destroy. After enough feeding, the larvae come to rest and an initial protein synthesis stage surges, culminating in the production of high amounts of protein. This occurs from day 1 to about day 8. Then, on day 9, cell death of salivary gland cells occurs. This pattern of synthesis and destruction is not to be confused with apoptosis, as no DNA degeneration is seen and cells are shown to vacuolate and swell (compared to condense and shrink in the case of apoptosis). Instead, selective expression and DNA synthesis is seen to support programmed cell death (of salivary gland cells).
Calliphora vomitoria