Theodosia Burr was born in 1783, and was named after her mother.
She was the only child of Burr's marriage to Theodosia Bartow Prevost who survived to adulthood.
A second daughter, Sally, lived to the age of three.

Burr was a devoted and attentive father to Theodosia.
Believing that a young woman should have an education equal to that of a young man, Burr prescribed a rigorous course of studies for her which included the classics, French, horsemanship, and music.
Their surviving correspondence indicates that he affectionately treated his daughter as a close friend and confidante as long as she lived.

Theodosia became widely known for her education and accomplishments.
In 1801, she married Joseph Alston of South Carolina.
They had a son together, Aaron Burr Alston, who died of fever at age ten.
During the winter of 1812–1813, Theodosia was lost at sea with the schooner Patriot off the Carolinas, either murdered by pirates or shipwrecked in a storm.
Theodosia Burr was born in 1783, and was named after her mother. She was the only child of Burr's marriage to Theodosia Bartow Prevost who survived to adulthood. A second daughter, Sally, lived to the age of three.
Burr was a devoted and attentive father to Theodosia. Believing that a young woman should have an education equal to that of a young man, Burr prescribed a rigorous course of studies for her which included the classics, French, horsemanship, and music. Their surviving correspondence indicates that he affectionately treated his daughter as a close friend and confidante as long as she lived.
Theodosia became widely known for her education and accomplishments. In 1801, she married Joseph Alston of South Carolina. They had a son together, Aaron Burr Alston, who died of fever at age ten. During the winter of 1812–1813, Theodosia was lost at sea with the schooner Patriot off the Carolinas, either murdered by pirates or shipwrecked in a storm.
Aaron Burr