In the Roman era, the term Syria is used to comprise the entire northern Levant and has an uncertain border to the northeast that Pliny the Elder describes as including, from west to east, the Kingdom of Commagene, Sophene, and Adiabene, "formerly known as Assyria".

Various writers used the term to describe the entire Levant region during this period; the New Testament used the name in this sense on numerous occasions.

In 64 BC, Syria became a province of the Roman Empire, following the conquest by Pompey.
Roman Syria bordered Judea to the south, Anatolian Greek domains to the north, Phoenicia to the West, and was in constant struggle with Parthians to the East.

In 135 AD, Syria-Palaestina became to incorporate the entire Levant and Western Mesopotamia.
In 193, the province was divided into Syria proper (Coele-Syria) and Phoenice.
Sometime between 330 and 350 (likely c. 341), the province of Euphratensis was created out of the territory of Syria Coele and the former realm of Commagene, with Hierapolis as its capital.

After c. 415 Syria Coele was further subdivided into Syria I, with the capital remaining at Antioch, and Syria II or Salutaris, with capital at Apamea on the Orontes River.
In 528, Justinian I carved out the small coastal province Theodorias out of territory from both provinces.
In the Roman era, the term Syria is used to comprise the entire northern Levant and has an uncertain border to the northeast that Pliny the Elder describes as including, from west to east, the Kingdom of Commagene, Sophene, and Adiabene, "formerly known as Assyria".
Various writers used the term to describe the entire Levant region during this period; the New Testament used the name in this sense on numerous occasions.
In 64 BC, Syria became a province of the Roman Empire, following the conquest by Pompey. Roman Syria bordered Judea to the south, Anatolian Greek domains to the north, Phoenicia to the West, and was in constant struggle with Parthians to the East.
In 135 AD, Syria-Palaestina became to incorporate the entire Levant and Western Mesopotamia. In 193, the province was divided into Syria proper (Coele-Syria) and Phoenice. Sometime between 330 and 350 (likely c. 341), the province of Euphratensis was created out of the territory of Syria Coele and the former realm of Commagene, with Hierapolis as its capital.
After c. 415 Syria Coele was further subdivided into Syria I, with the capital remaining at Antioch, and Syria II or Salutaris, with capital at Apamea on the Orontes River. In 528, Justinian I carved out the small coastal province Theodorias out of territory from both provinces.
Syria (region)