The interior, which can be reached from the original fifteenth-century door, has a short nave with cruciform vaulting and a tribune surmounted by a cupola.
Cortona articulated the interior of the dome with octagonal coffering and a series of ribs radiating from the lantern.
This is an early example of combining these two forms of dome decoration and was employed by Gianlorenzo Bernini in his later churches at Ariccia and Castelgandolfo.

Carlo Maderno designed the high altar (1614) to enframe the venerable icon of the Madonna and Child.
The interior, which can be reached from the original fifteenth-century door, has a short nave with cruciform vaulting and a tribune surmounted by a cupola. Cortona articulated the interior of the dome with octagonal coffering and a series of ribs radiating from the lantern. This is an early example of combining these two forms of dome decoration and was employed by Gianlorenzo Bernini in his later churches at Ariccia and Castelgandolfo.
Carlo Maderno designed the high altar (1614) to enframe the venerable icon of the Madonna and Child.
Santa Maria della Pace