During December 1943 and throughout 1944, Tillman escorted convoys between ports in the United States, the Mediterranean, and the United Kingdom.
Occasionally, she varied this duty with overhaul at New York or exercises off New England.
In the first three months of 1945, Tillman participated in exercises in the Caribbean and off the United States East Coast before departing on 28 March 1945 from the Delaware Bay and steaming via the Panama Canal Zone and San Diego, California, for Hawaii.

Following her arrival at Pearl Harbor on 21 April, she took part in exercises in Hawaiian waters, then departed the area on 1 May 1945.
Until September 1945, Tillman performed life guard and antisubmarine picket duties, based at Guam and Ulithi Atoll.
On 6 September 1945 at Tamil Harbor, the commanding officer of the Imperial Japanese Army garrison on Yap Island formally surrendered to the American atoll commander from Ulithi on board Tillman.

Tillman continued to operate in the Caroline Islands and southern Mariana Islands until 3 November 1945, when she proceeded to Pearl Harbor.
Then, continuing on, she steamed via the Panama Canal to the United States East Coast, arriving at Charleston on 11 December 1946 for inactivation.

Tillman was decommissioned on 6 February 1947.
During December 1943 and throughout 1944, Tillman escorted convoys between ports in the United States, the Mediterranean, and the United Kingdom. Occasionally, she varied this duty with overhaul at New York or exercises off New England. In the first three months of 1945, Tillman participated in exercises in the Caribbean and off the United States East Coast before departing on 28 March 1945 from the Delaware Bay and steaming via the Panama Canal Zone and San Diego, California, for Hawaii.
Following her arrival at Pearl Harbor on 21 April, she took part in exercises in Hawaiian waters, then departed the area on 1 May 1945. Until September 1945, Tillman performed life guard and antisubmarine picket duties, based at Guam and Ulithi Atoll. On 6 September 1945 at Tamil Harbor, the commanding officer of the Imperial Japanese Army garrison on Yap Island formally surrendered to the American atoll commander from Ulithi on board Tillman.
Tillman continued to operate in the Caroline Islands and southern Mariana Islands until 3 November 1945, when she proceeded to Pearl Harbor. Then, continuing on, she steamed via the Panama Canal to the United States East Coast, arriving at Charleston on 11 December 1946 for inactivation.
Tillman was decommissioned on 6 February 1947.
USS Tillman (DD-641)