Portions of Ocean's 11 were shot at the Desert Inn.
It is one of the five Las Vegas hotels robbed on New Year's Eve by the characters played by Frank Sinatra, Dean Martin and others in the film.
Orson Welles' film F for Fake covers, among other topics, the scandal of a fake biography of Howard Hughes, and the billionaire's Desert Inn residence is illustrated by Welles.
In the 1985 film Lost in America, Julie Hagerty's character Linda Howard loses the couple's "nest egg" at the Desert Inn, leading to a memorable scene in which Albert Brooks' character David Howard tries to convince the Casino manager (Garry Marshall) to give them their money back.
David, an ad man, proposes a campaign centered around the generosity of the casino in his case, replete with a jingle: "The Desert Inn has heart... The Desert Inn has heart."

The opening scene to the 1993 film Sister Act 2: Back in the Habit took place in the Grand Ballroom of the Hotel.
The Desert Inn saw its last commercial use in the 2001 film Rush Hour 2, shortly before it was imploded.
It was converted into the "Red Dragon", an Asian-themed casino set.

The hotel served as the primary backdrop for the TV show Vega$ which aired on ABC from 1978 to 1981.
The 1980s Aaron Spelling soap opera Dynasty included footage of the hotel, and use of the Presidential Suite.
The hit 1980s NBC TV series Remington Steele filmed its 60th Las Vegas-set episode at the inn, where both the exterior and interior are shown regularly throughout the episode.
Portions of Ocean's 11 were shot at the Desert Inn. It is one of the five Las Vegas hotels robbed on New Year's Eve by the characters played by Frank Sinatra, Dean Martin and others in the film. Orson Welles' film F for Fake covers, among other topics, the scandal of a fake biography of Howard Hughes, and the billionaire's Desert Inn residence is illustrated by Welles. In the 1985 film Lost in America, Julie Hagerty's character Linda Howard loses the couple's "nest egg" at the Desert Inn, leading to a memorable scene in which Albert Brooks' character David Howard tries to convince the Casino manager (Garry Marshall) to give them their money back. David, an ad man, proposes a campaign centered around the generosity of the casino in his case, replete with a jingle: "The Desert Inn has heart... The Desert Inn has heart."
The opening scene to the 1993 film Sister Act 2: Back in the Habit took place in the Grand Ballroom of the Hotel. The Desert Inn saw its last commercial use in the 2001 film Rush Hour 2, shortly before it was imploded. It was converted into the "Red Dragon", an Asian-themed casino set.
The hotel served as the primary backdrop for the TV show Vega$ which aired on ABC from 1978 to 1981. The 1980s Aaron Spelling soap opera Dynasty included footage of the hotel, and use of the Presidential Suite. The hit 1980s NBC TV series Remington Steele filmed its 60th Las Vegas-set episode at the inn, where both the exterior and interior are shown regularly throughout the episode.
Desert Inn