On January 14, 2009, Belisle signed a minor league contract with the Colorado Rockies.

Belisle enjoyed the best season of his career with the Rockies in 2010, mostly as a setup pitcher, posting a 7-5 record, 2.93 ERA, 91 K in 92 innings of work.
He led all big league relievers with his 92 innings pitched.

In January 2011, he avoided salary arbitration with Colorado by signing a 1-year deal worth $2.35 million.
The Rockies signed Belisle to a new two-year deal worth $6.125 million a month later that overwrote his prior deal, and also got him under contract an extra year before hitting free agency.
In addition, it included an incentive in which he would earn an additional $225,000 in bonuses based on games finished.
He proceeded to compile a 10-4 record with a 3.25 ERA and 58 Ks in 72 IP.

Before the 2012 season, he agreed to a two-year extension (which added a $4.1 million salary for 2013 and included a mutual option for 2014) at a minimum of $4.35 million.
 He went on to pitch to a 3.71 earned run average with a 3-9 record as well as 69 strikeouts in 80 innings.

The 33-year-old Belisle came into 2013 being considered as one of the Rockies' more reliable relievers.
He compiled a record of 5-7 with a 4.32 ERA in 72 games.
On January 14, 2009, Belisle signed a minor league contract with the Colorado Rockies.
Belisle enjoyed the best season of his career with the Rockies in 2010, mostly as a setup pitcher, posting a 7-5 record, 2.93 ERA, 91 K in 92 innings of work. He led all big league relievers with his 92 innings pitched.
In January 2011, he avoided salary arbitration with Colorado by signing a 1-year deal worth $2.35 million. The Rockies signed Belisle to a new two-year deal worth $6.125 million a month later that overwrote his prior deal, and also got him under contract an extra year before hitting free agency. In addition, it included an incentive in which he would earn an additional $225,000 in bonuses based on games finished. He proceeded to compile a 10-4 record with a 3.25 ERA and 58 Ks in 72 IP.
Before the 2012 season, he agreed to a two-year extension (which added a $4.1 million salary for 2013 and included a mutual option for 2014) at a minimum of $4.35 million.  He went on to pitch to a 3.71 earned run average with a 3-9 record as well as 69 strikeouts in 80 innings.
The 33-year-old Belisle came into 2013 being considered as one of the Rockies' more reliable relievers. He compiled a record of 5-7 with a 4.32 ERA in 72 games.
Matt Belisle