In 1962, she was redesignated DD-577.
During the Cuban Missile Crisis in October 1962, Sproston, which was deployed to the Seventh Fleet at the time, was detailed to patrol the straits of Tsushima to block any attempt by Soviet submarines to sortie from the Sea of Japan into the Pacific.
 The only submarine encountered was the USS Queenfish.
During the transit back to Hawaii in December 1962, Sproston was part of the Hornet group which had taken the great circle course across the northern Pacific.
 Several days prior to their scheduled arrival at Pearl Harbor, the group ran into a heavy gale, with winds in excess of 60 knots, accompanied by towering seas.
 Damage among the ships of the group was so extensive, they had to put into Midway for voyage repairs.
 A great circle route is the shortest sailing distance on the earth's spherical surface, and was taken in order to arrive home for Christmas as quickly as possible.
 However, it was ill-advised to do so in the North Pacific in winter, when storms such as that encountered are the norm.
Thus the ships arrived later than if they had sailed the longer southern rhumb line route. "
The best laid plans .
 . . ."
 Normal operating duties continued through 1963 and 1964.
In March 1965, she began a five-month overhaul in the Pearl Harbor Navy Yard.
When this was completed, she conducted extensive refresher training to prepare her crew for deployment to the western Pacific.

Sproston departed Pearl Harbor on 27 December with Ranger (CVA-61), England (DLG-22), and Carpenter (DD-825) and headed, via Subic Bay, for the Vietnam coast.
The group arrived at Dixie Station off the coast of South Vietnam on 16 January 1966 and remained there until 13 February.
Sproston was assigned rescue and antisubmarine screening duties.
On the 18th, she was directed to proceed to Phuoc Hui Bay to provide naval gunfire support.
During the night, the ship shelled Viet Cong base camps and assembly areas.

On 19 January 1966 she rejoined the carrier task group which had moved to Yankee Station in the Gulf of Tonkin.
Sproston was detached from 5–11 February to perform trawler surveillance and blocking.
During this time, she observed a Russian Okean-class vessel, the Gidrofon, which was believed to be gathering electronic and tactical information.
She rejoined the carrier group which returned to Subic Bay until 22 February.

Back at Yankee Station, Sproston was again detached for naval gunfire support duty.
She arrived off the coast, in the II Corps area, on 1 March and remained there until the 20th, firing 40 support missions for the 1st Cavalry Division and South Vietnamese Marines.
The most eventful came on 9 March when, during a three-hour battle, her guns helped to repulse a battalion-strength Viet Cong attack against Republic of Vietnam Marines near Tam Quan.

On 21 March, she and the Task Group proceeded to Yokosuka whence it departed on 5 April for another tour at Dixie Station.
Sproston worked with Ranger at both Dixie Station and Yankee Station during the patrol.

Sproston was detached from the Task Group on 4 May and visited Hong Kong, Subic Bay, and Yokosuka before she returned to Pearl Harbor for upkeep and the installation of a recovery crane as she had been selected to participate in an Apollo spacecraft recovery.

On 25 August, she was on station off Kwajalein when the spacecraft passed overhead and landed 200 nautical miles (370 km) north, where it was recovered by Hornet (CVS-12).
Sproston returned to Pearl Harbor on 2 September and remained there undergoing repair services and conducting type training for the remainder of the year.

In January and February 1967, Sproston conducted local operations to prepare for her 1967 deployment to the Far East.
She sailed for Yokosuka on 6 March and, one month later, was back at Yankee Station.
She participated in Operation Sea Lion and provided gunfire support until 14 May. She then joined Hancock (CVA-19) as escort and plane guard for two and one-half months.
During this period of deployment, she performed trawler surveillance duty at Yankee Station several
In 1962, she was redesignated DD-577. During the Cuban Missile Crisis in October 1962, Sproston, which was deployed to the Seventh Fleet at the time, was detailed to patrol the straits of Tsushima to block any attempt by Soviet submarines to sortie from the Sea of Japan into the Pacific.  The only submarine encountered was the USS Queenfish. During the transit back to Hawaii in December 1962, Sproston was part of the Hornet group which had taken the great circle course across the northern Pacific.  Several days prior to their scheduled arrival at Pearl Harbor, the group ran into a heavy gale, with winds in excess of 60 knots, accompanied by towering seas.  Damage among the ships of the group was so extensive, they had to put into Midway for voyage repairs.  A great circle route is the shortest sailing distance on the earth's spherical surface, and was taken in order to arrive home for Christmas as quickly as possible.  However, it was ill-advised to do so in the North Pacific in winter, when storms such as that encountered are the norm. Thus the ships arrived later than if they had sailed the longer southern rhumb line route. "The best laid plans .  . . ."  Normal operating duties continued through 1963 and 1964. In March 1965, she began a five-month overhaul in the Pearl Harbor Navy Yard. When this was completed, she conducted extensive refresher training to prepare her crew for deployment to the western Pacific.
Sproston departed Pearl Harbor on 27 December with Ranger (CVA-61), England (DLG-22), and Carpenter (DD-825) and headed, via Subic Bay, for the Vietnam coast. The group arrived at Dixie Station off the coast of South Vietnam on 16 January 1966 and remained there until 13 February. Sproston was assigned rescue and antisubmarine screening duties. On the 18th, she was directed to proceed to Phuoc Hui Bay to provide naval gunfire support. During the night, the ship shelled Viet Cong base camps and assembly areas.
On 19 January 1966 she rejoined the carrier task group which had moved to Yankee Station in the Gulf of Tonkin. Sproston was detached from 5–11 February to perform trawler surveillance and blocking. During this time, she observed a Russian Okean-class vessel, the Gidrofon, which was believed to be gathering electronic and tactical information. She rejoined the carrier group which returned to Subic Bay until 22 February.
Back at Yankee Station, Sproston was again detached for naval gunfire support duty. She arrived off the coast, in the II Corps area, on 1 March and remained there until the 20th, firing 40 support missions for the 1st Cavalry Division and South Vietnamese Marines. The most eventful came on 9 March when, during a three-hour battle, her guns helped to repulse a battalion-strength Viet Cong attack against Republic of Vietnam Marines near Tam Quan.
On 21 March, she and the Task Group proceeded to Yokosuka whence it departed on 5 April for another tour at Dixie Station. Sproston worked with Ranger at both Dixie Station and Yankee Station during the patrol.
Sproston was detached from the Task Group on 4 May and visited Hong Kong, Subic Bay, and Yokosuka before she returned to Pearl Harbor for upkeep and the installation of a recovery crane as she had been selected to participate in an Apollo spacecraft recovery.
On 25 August, she was on station off Kwajalein when the spacecraft passed overhead and landed 200 nautical miles (370 km) north, where it was recovered by Hornet (CVS-12). Sproston returned to Pearl Harbor on 2 September and remained there undergoing repair services and conducting type training for the remainder of the year.
In January and February 1967, Sproston conducted local operations to prepare for her 1967 deployment to the Far East. She sailed for Yokosuka on 6 March and, one month later, was back at Yankee Station. She participated in Operation Sea Lion and provided gunfire support until 14 May. She then joined Hancock (CVA-19) as escort and plane guard for two and one-half months. During this period of deployment, she performed trawler surveillance duty at Yankee Station several
USS Sproston (DD-577)