Sultan Suleiman's two known consorts (Hürrem and Mahidevran) had borne him six sons, four of whom survived past the 1550s.
They were Mustafa, Selim, Bayezid, and Cihangir.
Of these, the eldest was not Hürrem's son, but rather Mahidevran's.
Hürrem is usually held at least partly responsible for the intrigues in nominating a successor, though there is no evidence to support this.
Although she was Suleiman's wife, she exercised no official public role.
This did not, however, prevent Hürrem from wielding powerful political influence.
Since the Empire lacked, until the reign of Ahmed I, any formal means of nominating a successor, successions usually involved the death of competing princes in order to avert civil unrest and rebellions.

By 1552, when the campaign against Persia had begun with Rüstem appointed commander-in-chief of the expedition, intrigues against Mustafa began.
Rüstem sent one of Suleiman's most trusted men to report that since Suleiman was not at the head of the army, the soldiers thought the time had come to put a younger prince on the throne; at the same time he spread rumours that Mustafa had proved receptive to the idea.
Angered by what he came to believe were Mustafa's plans to claim the throne, the following summer upon return from his campaign in Persia, Suleiman summoned him to his tent in the Ereğli valley.
When Mustafa entered his father's tent to meet with him, Suleiman's eunuchs attacked Mustafa, and after a long struggle the mutes killed him using a bow-string.

Cihangir is said to have died of grief a few months after the news of his half-brother's murder.
The two surviving brothers, Selim and Bayezid, were given command in different parts of the empire.
Within a few years, however, civil war broke out between the brothers, each supported by his loyal forces.
With the aid of his father's army, Selim defeated Bayezid in Konya in 1559, leading the latter to seek refuge with the Safavids along with his four sons.
Following diplomatic exchanges, the Sultan demanded from the Safavid Shah that Bayezid be either extradited or executed.
In return for large amounts of gold, the Shah allowed a Turkish executioner to strangle Bayezid and his four sons in 1561, clearing the path for Selim's succession to the throne five years later.
Sultan Suleiman's two known consorts (Hürrem and Mahidevran) had borne him six sons, four of whom survived past the 1550s. They were Mustafa, Selim, Bayezid, and Cihangir. Of these, the eldest was not Hürrem's son, but rather Mahidevran's. Hürrem is usually held at least partly responsible for the intrigues in nominating a successor, though there is no evidence to support this. Although she was Suleiman's wife, she exercised no official public role. This did not, however, prevent Hürrem from wielding powerful political influence. Since the Empire lacked, until the reign of Ahmed I, any formal means of nominating a successor, successions usually involved the death of competing princes in order to avert civil unrest and rebellions.
By 1552, when the campaign against Persia had begun with Rüstem appointed commander-in-chief of the expedition, intrigues against Mustafa began. Rüstem sent one of Suleiman's most trusted men to report that since Suleiman was not at the head of the army, the soldiers thought the time had come to put a younger prince on the throne; at the same time he spread rumours that Mustafa had proved receptive to the idea. Angered by what he came to believe were Mustafa's plans to claim the throne, the following summer upon return from his campaign in Persia, Suleiman summoned him to his tent in the Ereğli valley. When Mustafa entered his father's tent to meet with him, Suleiman's eunuchs attacked Mustafa, and after a long struggle the mutes killed him using a bow-string.
Cihangir is said to have died of grief a few months after the news of his half-brother's murder. The two surviving brothers, Selim and Bayezid, were given command in different parts of the empire. Within a few years, however, civil war broke out between the brothers, each supported by his loyal forces. With the aid of his father's army, Selim defeated Bayezid in Konya in 1559, leading the latter to seek refuge with the Safavids along with his four sons. Following diplomatic exchanges, the Sultan demanded from the Safavid Shah that Bayezid be either extradited or executed. In return for large amounts of gold, the Shah allowed a Turkish executioner to strangle Bayezid and his four sons in 1561, clearing the path for Selim's succession to the throne five years later.
Suleiman the Magnificent