The ligand found in amavadin was first synthesized in 1954.
Amavadin contains vanadium(IV).
Initially, amavadin was thought to have a vanadyl, VO²⁺, center.
In 1993, it was discovered by crystallographic characterization that amavadin is not a vanadyl ion compound.
Instead, it is an octacoordinated vanadium(IV) complex.
This complex is bonded to two tetradentate ligands derived from N-hydroxyimino-2,2'-dipropionic acid, H₃(HIDPA), ligands.
The ligands coordinate through the nitrogen and the three oxygen centers.

Amavadin is a C₂-symmetric anion with a 2− charge.
The twofold axis bisects the vanadium atom perpendicular to the two NO ligands.
The anion features five chiral centers, one at vanadium and the four carbon atoms having S stereochemistry.
There are two possible diastereomers for the ligands, (S,S)-(S,S)-Δ and (S,S)-(S,S)-Λ.
The ligand found in amavadin was first synthesized in 1954. Amavadin contains vanadium(IV). Initially, amavadin was thought to have a vanadyl, VO²⁺, center. In 1993, it was discovered by crystallographic characterization that amavadin is not a vanadyl ion compound. Instead, it is an octacoordinated vanadium(IV) complex. This complex is bonded to two tetradentate ligands derived from N-hydroxyimino-2,2'-dipropionic acid, H₃(HIDPA), ligands. The ligands coordinate through the nitrogen and the three oxygen centers.
Amavadin is a C₂-symmetric anion with a 2− charge. The twofold axis bisects the vanadium atom perpendicular to the two NO ligands. The anion features five chiral centers, one at vanadium and the four carbon atoms having S stereochemistry. There are two possible diastereomers for the ligands, (S,S)-(S,S)-Δ and (S,S)-(S,S)-Λ.
Amavadin