On September 19, 2010, Edwards signed a one-year contract extension to ride for Tech 3 Yamaha in the 2011 season, partnering Cal Crutchlow.

At the Catalan Grand Prix, Edwards broke his right collarbone during second practice, which successfully had a plate added.
Nine days later, and in his first race since injury, Edwards took a third-place finish at the British Grand Prix at Silverstone, having been promoted to a podium placing after accidents for Jorge Lorenzo and Marco Simoncelli.
It was his first podium finish since a second-place result at the 2009 British Grand Prix at Donington Park.

On October 23, along with Valentino Rossi, Edwards was involved in the accident that killed Marco Simoncelli at the Malaysian Grand Prix, injuring his left shoulder and ending his season.
Josh Hayes replaced him for Valencia.
On September 19, 2010, Edwards signed a one-year contract extension to ride for Tech 3 Yamaha in the 2011 season, partnering Cal Crutchlow.
At the Catalan Grand Prix, Edwards broke his right collarbone during second practice, which successfully had a plate added. Nine days later, and in his first race since injury, Edwards took a third-place finish at the British Grand Prix at Silverstone, having been promoted to a podium placing after accidents for Jorge Lorenzo and Marco Simoncelli. It was his first podium finish since a second-place result at the 2009 British Grand Prix at Donington Park. 
On October 23, along with Valentino Rossi, Edwards was involved in the accident that killed Marco Simoncelli at the Malaysian Grand Prix, injuring his left shoulder and ending his season. Josh Hayes replaced him for Valencia.
Colin Edwards