At Milan he lived by teaching Humanities, while continuing to study Law with Sfondrati.
To avoid the constant warfare in the Duchy he accepted an invitation from Gian Giorgio, Marchese of Montferrat.
He remained at the court of Casale Monferrato for a while after the Marchese's death on 3 April 1533: his first daughter, future wife of Girolamo Zanchi, was born at Ceva on 8 November, and his second son Orazio at Casale in 1534.
Here he became acquainted with Fulvio Pellegrino Morato, professor at Vicenza, who was visiting Piedmont: they agreed in religious matters so much that Morato later said that Curio had been for him what Ananias had been for St Paul.

His brethren having died of the plague Curio should have returned to Moncalieri to settle his inheritance with his only surviving sister, but, faced with being denounced for heresy, he renounced his rights.
Having failed to respond to a summons to Casale from Federico Gonzaga, successor to the Marquessate, he took work as a teacher at Castiglione Torinese, where in a disputation with a Dominican preacher in 1535 he argued in defence of Luther.
Denounced to the Suffragan of Turin he was imprisoned, but managed to escape by tricking the gaoler into shackling a false leg to the cell wall and escaping through the unbarred window.
As the mystery of his escape gave rise to superstitious rumours, he later explained how it was managed in a Dialogue, Probus.
He took refuge at Salò, where he was reunited with his family: two of his sons were born there, Leo in 1536 and Agostino in 1538.
At Milan he lived by teaching Humanities, while continuing to study Law with Sfondrati. To avoid the constant warfare in the Duchy he accepted an invitation from Gian Giorgio, Marchese of Montferrat. He remained at the court of Casale Monferrato for a while after the Marchese's death on 3 April 1533: his first daughter, future wife of Girolamo Zanchi, was born at Ceva on 8 November, and his second son Orazio at Casale in 1534. Here he became acquainted with Fulvio Pellegrino Morato, professor at Vicenza, who was visiting Piedmont: they agreed in religious matters so much that Morato later said that Curio had been for him what Ananias had been for St Paul.
His brethren having died of the plague Curio should have returned to Moncalieri to settle his inheritance with his only surviving sister, but, faced with being denounced for heresy, he renounced his rights. Having failed to respond to a summons to Casale from Federico Gonzaga, successor to the Marquessate, he took work as a teacher at Castiglione Torinese, where in a disputation with a Dominican preacher in 1535 he argued in defence of Luther. Denounced to the Suffragan of Turin he was imprisoned, but managed to escape by tricking the gaoler into shackling a false leg to the cell wall and escaping through the unbarred window. As the mystery of his escape gave rise to superstitious rumours, he later explained how it was managed in a Dialogue, Probus. He took refuge at Salò, where he was reunited with his family: two of his sons were born there, Leo in 1536 and Agostino in 1538.
Celio Secondo Curione