There is a prehistoric ditch on the slopes of Tidcombe Down, south and southwest of the village; part of the western boundary of the parish follows it.
Also on the down is a Neolithic long barrow, 54m long.
The eastern boundary of the ancient parish followed the Roman road from Cirencester to Winchester, known in this area as Chute Causeway; on this section, between Marlborough in the northwest and Andover in the southeast, the road deviates south to avoid the dry valleys around Hippenscombe.

Domesday Book of 1086 recorded nine households at Titicome.
Tidcombe lay within Savernake Forest until 1330.

Lords of the manor included William Esturmy of Wulfhall (died 1427; MP and Speaker of the House of Commons) and John Seymour (died 1464, also an MP).
By 1540 the manor had been acquired by Edward Seymour (brother of queen consort Jane Seymour; later Duke of Somerset and Lord Protector; executed 1552) and it passed to his son Edward Seymour, 1st Earl of Hertford (1539–1621).
The manor remained with the Dukes of Somerset, alongside Tottenham until 1675, and was then held by the Seymours alongside Pewsey until sold around 1767 by Hugh Percy, 1st Duke of Northumberland and his wife Elizabeth (née Seymour) to Edward Tanner (d.1779).

Tanner's son John (d.1797) was probably the builder of the manor house, near the church.
In brick and stone dressings and with a five-bay front, it is now Grade II* listed.

In the 19th century, the names Tidcombe and Titcombe were both in use.
There is a prehistoric ditch on the slopes of Tidcombe Down, south and southwest of the village; part of the western boundary of the parish follows it. Also on the down is a Neolithic long barrow, 54m long. The eastern boundary of the ancient parish followed the Roman road from Cirencester to Winchester, known in this area as Chute Causeway; on this section, between Marlborough in the northwest and Andover in the southeast, the road deviates south to avoid the dry valleys around Hippenscombe.
Domesday Book of 1086 recorded nine households at Titicome. Tidcombe lay within Savernake Forest until 1330.
Lords of the manor included William Esturmy of Wulfhall (died 1427; MP and Speaker of the House of Commons) and John Seymour (died 1464, also an MP). By 1540 the manor had been acquired by Edward Seymour (brother of queen consort Jane Seymour; later Duke of Somerset and Lord Protector; executed 1552) and it passed to his son Edward Seymour, 1st Earl of Hertford (1539–1621). The manor remained with the Dukes of Somerset, alongside Tottenham until 1675, and was then held by the Seymours alongside Pewsey until sold around 1767 by Hugh Percy, 1st Duke of Northumberland and his wife Elizabeth (née Seymour) to Edward Tanner (d.1779).
Tanner's son John (d.1797) was probably the builder of the manor house, near the church. In brick and stone dressings and with a five-bay front, it is now Grade II* listed.
In the 19th century, the names Tidcombe and Titcombe were both in use.
Tidcombe