A larger Tundra was introduced at the February 2006 Chicago Auto Show.
It used styling cues from the Toyota Tacoma along with some cues from the Toyota FTX concept truck (also designed by Craig Kember in 2003).
The truck featured towing capacity of up to 10,000 lb, and a payload capacity of over 2,000 lb (910 kg), a new 5.7-liter 3UR-FE V8 engine mated to a new 6-speed automatic transmission.
The second generation Tundra had three engine options.
The new 5.7-liter V8 that produces 381 hp (284 kW; 386 PS) and 401 lb⋅ft (544 N⋅m) of torque, and the carry over 4.7-liter 2UZ-FE V8 rated at 276 hp (206 kW; 280 PS) and 313 pound force-feet (424 N⋅m) of torque, as well as the previous 4.0-liter 1GR-FE V6 rated at 236 hp (176 kW; 239 PS) and 266 lb⋅ft (361 N⋅m) of torque.

When the new Tundra was first launched in January 2007, it was available in 31 configurations, which consisted of 3 bed lengths, 3 cab configurations, 3 wheelbases, and 2 transmissions.
The new Double Cab replaces the previous generation's Access Cab, and the all new CrewMax replaces the previous generation's Double Cab, it is also built to compete with the Dodge Ram Mega Cab.
The Double Cab and Regular Cab are available with a 6.5-foot (2.0 m) regular bed or an 8-foot (2.4 m) long bed, while the CrewMax is only available with a 5.5-foot (1.7 m) short bed.
The Tundra also features a new 6-speed automatic transmission which can lock the torque converter in 5th and 6th gears with a manual shift mode which is standard with the 5.7-liter, giving it a 0–60 mph (0–97 km/h) time of 6.3 seconds and a quarter mile time of 14.7 seconds.

Toyota made the new Tundra useful for many construction workers by including extra large door handles, deck rail system, integrated tow hitch, and head restraints that can fit a worker with a hardhat.
The Tundra also includes as standard: an electronic automatic limited-slip differential (Auto LSD), Vehicle Stability Control, traction control, electronic brakeforce distribution, brake assist, anti-lock brakes and tailgate assist.
However, its starting price was more expensive than the Chevrolet Silverado Work Truck and the base Ford F-150.

Some other changes Toyota included in the new Tundra are optional tow mirrors, a 26.4 US gal (100 L; 22 imp gal) fuel tank, available 22-inch (560 mm) alloy wheels, backup camera, Bluetooth, large center console (big enough to fit a 15-inch (380 mm) laptop), extra-large disc brakes and calipers, and the aforementioned 6-speed sequential automatic transmission.

All 5.7-liter Tundras come equipped with a tow package which includes engine oil and transmission coolers, integrated trailer hitch, 4.30:1 axle ratio, and large braking hardware for increased fade resistance.
 Equipped with the 5.7-liter V8 the Tundra has a maximum tow rating of 9,000–10,400 lb (4,100–4,700 kg) depending on body configuration.
 Toyota began rating the Tundra under the SAE J2807 protocol beginning in 2010.
A larger Tundra was introduced at the February 2006 Chicago Auto Show. It used styling cues from the Toyota Tacoma along with some cues from the Toyota FTX concept truck (also designed by Craig Kember in 2003). The truck featured towing capacity of up to 10,000 lb, and a payload capacity of over 2,000 lb (910 kg), a new 5.7-liter 3UR-FE V8 engine mated to a new 6-speed automatic transmission. The second generation Tundra had three engine options. The new 5.7-liter V8 that produces 381 hp (284 kW; 386 PS) and 401 lb⋅ft (544 N⋅m) of torque, and the carry over 4.7-liter 2UZ-FE V8 rated at 276 hp (206 kW; 280 PS) and 313 pound force-feet (424 N⋅m) of torque, as well as the previous 4.0-liter 1GR-FE V6 rated at 236 hp (176 kW; 239 PS) and 266 lb⋅ft (361 N⋅m) of torque.
When the new Tundra was first launched in January 2007, it was available in 31 configurations, which consisted of 3 bed lengths, 3 cab configurations, 3 wheelbases, and 2 transmissions. The new Double Cab replaces the previous generation's Access Cab, and the all new CrewMax replaces the previous generation's Double Cab, it is also built to compete with the Dodge Ram Mega Cab. The Double Cab and Regular Cab are available with a 6.5-foot (2.0 m) regular bed or an 8-foot (2.4 m) long bed, while the CrewMax is only available with a 5.5-foot (1.7 m) short bed. The Tundra also features a new 6-speed automatic transmission which can lock the torque converter in 5th and 6th gears with a manual shift mode which is standard with the 5.7-liter, giving it a 0–60 mph (0–97 km/h) time of 6.3 seconds and a quarter mile time of 14.7 seconds.
Toyota made the new Tundra useful for many construction workers by including extra large door handles, deck rail system, integrated tow hitch, and head restraints that can fit a worker with a hardhat. The Tundra also includes as standard: an electronic automatic limited-slip differential (Auto LSD), Vehicle Stability Control, traction control, electronic brakeforce distribution, brake assist, anti-lock brakes and tailgate assist. However, its starting price was more expensive than the Chevrolet Silverado Work Truck and the base Ford F-150.
Some other changes Toyota included in the new Tundra are optional tow mirrors, a 26.4 US gal (100 L; 22 imp gal) fuel tank, available 22-inch (560 mm) alloy wheels, backup camera, Bluetooth, large center console (big enough to fit a 15-inch (380 mm) laptop), extra-large disc brakes and calipers, and the aforementioned 6-speed sequential automatic transmission.
All 5.7-liter Tundras come equipped with a tow package which includes engine oil and transmission coolers, integrated trailer hitch, 4.30:1 axle ratio, and large braking hardware for increased fade resistance.  Equipped with the 5.7-liter V8 the Tundra has a maximum tow rating of 9,000–10,400 lb (4,100–4,700 kg) depending on body configuration.  Toyota began rating the Tundra under the SAE J2807 protocol beginning in 2010.
Toyota Tundra