On 2 February 2011, Paparizou was one of eight acts performing at MAD TV's first charity fashion music show MADWalk—Greece's version of the international Fashion Rocks.
She represented fashion designer Apostolos Mitropoulos and performed her new single "Baby It's Over", which was the lead single from her three-disc compilation Greatest Hits & More.
She appeared at the Flight Night Club in Sofia, Bulgaria on 8 February. "
Baby It's Over" debuted at number one the Billboard Greek Digital Singles Chart; it was her fourth number one hit on that chart and her first single to top any Greek chart in three years.
It also topped the Greek Airplay Chart for ten non-consecutive weeks, becoming the most successful single of her career.
The song won two awards at the 2011 MAD Video Music Awards for Female Artist of the Year and Fashion Icon of the Year.
Paparizou was nominated for Artist of the Year and received a fourth nomination for Best Pop Video for "Psahno Tin Alitheia".
The album's second single, "Love Me Crazy"—released in Greek as "O,ti Niotho Den Allazi"—was released in May 2011, and peaked at number five on the airplay chart.
The songs' lyrics, particularly those of the lead single, caused speculation that Paparizou's twelve-year relationship with Mavridis had ended, which was proved to be correct.
Greatest Hits & More was released on 23 May; it debuted at number two on the Greek Albums Chart where it stayed for three weeks, and was the best-selling domestic album of the week.

Paparizou spent the next six months in Sweden with family and friends.
In June 2011, she announced that Mavridis would no longer be her manager and that she had recruited a new team of Swedish collaborators.
Her only professional appearances were at a four-date tour to Cyprus.
Paparizou wanted to revive her career in Sweden—which had declined since 2006—and to expand her career outside music.
She announced a second English-language album and European tour, along with possible participation in Melodifestivalen—which she had turned down in the past.
She also considered moving back to Sweden permanently.
She also said that any future collaborations with Mavridis in the future would be decided by her label.
In the third quarter of 2011, Paparizou recorded a duet of the nisiotiko classic "Dari Dari" with Nana Mouskouri for her duet album Tragoudia Apo Ta Ellinika Nisia (Songs from the Greek islands), and was a guest performer at the Mouskouri's anniversary concert at the Berlin Philharmonic on 29 November.
Although she had originally declined offers to perform during the winter season 2011–12, from 18 November she performed as a supporting act for Yiannis Parios in Thessaloniki.

Paparizou made her television debut as a judge on the first season of ANT1's Dancing on Ice from 6 November to 22 January withshow polarised critics.
Following her television debut, Paparizou received offers to appear on Dancing with the Stars, including as a contestant.
She instead appeared on the Swedish version, Let's Dance in early 2012, partnered with David Watson.
Initially considered one of the favourites to win, she received moderate scores and was voted off in the third episode, placing ninth out of ten contestants.

In December, Paparizou released the single "Mr. Perfect", which peaked at number seven on the digital chart and reached the top 30 in the airplay chart.
The song was remixed by Playmen, who with Paparizou performed it along with Joan Jett and the Blackhearts' "I Hate Myself for Loving You" at the 2012 MADWalk on 2 February 2012.
The song's video earned her three nominations for Best Pop Video, Female Artist of the Year, and Artist of the Year at the 2012 MAD Video Music Awards, while "Baby It's Over" gained a fourth nomination for MAD 106.2 Track of the Year; she won the awards for Female Artist and Track of the Year.
Paparizou performed a cabaret version of Eric Saade's "Popular" for the final of Melodifestivalen 2012.

At the 2012 MAD Video Music Awards, Paparizou performed a new version of the ballad "Poios" from Vrisko To Logo Na Zo, and was also featured in
On 2 February 2011, Paparizou was one of eight acts performing at MAD TV's first charity fashion music show MADWalk—Greece's version of the international Fashion Rocks. She represented fashion designer Apostolos Mitropoulos and performed her new single "Baby It's Over", which was the lead single from her three-disc compilation Greatest Hits & More. She appeared at the Flight Night Club in Sofia, Bulgaria on 8 February. "Baby It's Over" debuted at number one the Billboard Greek Digital Singles Chart; it was her fourth number one hit on that chart and her first single to top any Greek chart in three years. It also topped the Greek Airplay Chart for ten non-consecutive weeks, becoming the most successful single of her career. The song won two awards at the 2011 MAD Video Music Awards for Female Artist of the Year and Fashion Icon of the Year. Paparizou was nominated for Artist of the Year and received a fourth nomination for Best Pop Video for "Psahno Tin Alitheia". The album's second single, "Love Me Crazy"—released in Greek as "O,ti Niotho Den Allazi"—was released in May 2011, and peaked at number five on the airplay chart. The songs' lyrics, particularly those of the lead single, caused speculation that Paparizou's twelve-year relationship with Mavridis had ended, which was proved to be correct. Greatest Hits & More was released on 23 May; it debuted at number two on the Greek Albums Chart where it stayed for three weeks, and was the best-selling domestic album of the week.
Paparizou spent the next six months in Sweden with family and friends. In June 2011, she announced that Mavridis would no longer be her manager and that she had recruited a new team of Swedish collaborators. Her only professional appearances were at a four-date tour to Cyprus. Paparizou wanted to revive her career in Sweden—which had declined since 2006—and to expand her career outside music. She announced a second English-language album and European tour, along with possible participation in Melodifestivalen—which she had turned down in the past. She also considered moving back to Sweden permanently. She also said that any future collaborations with Mavridis in the future would be decided by her label. In the third quarter of 2011, Paparizou recorded a duet of the nisiotiko classic "Dari Dari" with Nana Mouskouri for her duet album Tragoudia Apo Ta Ellinika Nisia (Songs from the Greek islands), and was a guest performer at the Mouskouri's anniversary concert at the Berlin Philharmonic on 29 November. Although she had originally declined offers to perform during the winter season 2011–12, from 18 November she performed as a supporting act for Yiannis Parios in Thessaloniki.
Paparizou made her television debut as a judge on the first season of ANT1's Dancing on Ice from 6 November to 22 January withshow polarised critics. Following her television debut, Paparizou received offers to appear on Dancing with the Stars, including as a contestant. She instead appeared on the Swedish version, Let's Dance in early 2012, partnered with David Watson. Initially considered one of the favourites to win, she received moderate scores and was voted off in the third episode, placing ninth out of ten contestants.
In December, Paparizou released the single "Mr. Perfect", which peaked at number seven on the digital chart and reached the top 30 in the airplay chart. The song was remixed by Playmen, who with Paparizou performed it along with Joan Jett and the Blackhearts' "I Hate Myself for Loving You" at the 2012 MADWalk on 2 February 2012. The song's video earned her three nominations for Best Pop Video, Female Artist of the Year, and Artist of the Year at the 2012 MAD Video Music Awards, while "Baby It's Over" gained a fourth nomination for MAD 106.2 Track of the Year; she won the awards for Female Artist and Track of the Year. Paparizou performed a cabaret version of Eric Saade's "Popular" for the final of Melodifestivalen 2012.
At the 2012 MAD Video Music Awards, Paparizou performed a new version of the ballad "Poios" from Vrisko To Logo Na Zo, and was also featured in
Helena Paparizou