The organ chorale prelude BWV 622 by Johann Sebastian Bach from the Orgelbüchlein has remained one of his most celebrated.
In the second version of his St John Passion, Bach began the work with a chorale fantasia on the first stanza of the hymn, which he later modified to conclude Part I of his St Matthew Passion as movement 29.

Mauricio Kagel quoted the hymn in his oratorio Sankt-Bach-Passion telling Bach's life, composed for the tricentenary of Bach's birth in 1985.
The organ chorale prelude BWV 622 by Johann Sebastian Bach from the Orgelbüchlein has remained one of his most celebrated. In the second version of his St John Passion, Bach began the work with a chorale fantasia on the first stanza of the hymn, which he later modified to conclude Part I of his St Matthew Passion as movement 29.
Mauricio Kagel quoted the hymn in his oratorio Sankt-Bach-Passion telling Bach's life, composed for the tricentenary of Bach's birth in 1985.
O Mensch, bewein dein Sünde groß