Following Poland's return to independence in the aftermath of World War I, the town grew significantly.
Streets were paved and the marketplace rebuilt.
According to 1921 census, Izbica had 3,085 inhabitants including 2,862 Jews, but by 1939, the total number grew to roughly 6,000 with 5,098 Jews.
Izbica expanded particularly well because of the paved Lublin-Zamość thoroughfare, and a railway line to Zamość inaugurated in 1917.

Following the German and Soviet invasion of Poland in 1939 during the opening stages of World War II the town was overrun by the Nazis.
A number of prominent Polish Christians were arrested and murdered in the course of the AB Action against Polish intelligentsia.
  Jews were brutalized and robbed from the beginning of the occupation.
The Germans resettled thousands of other Jews in Izbica beginning at the end of 1939.
 These included deportees from Biała Podlaska, Komarówka, Wohyń, and Czemierniki arrived.
Almost the entire town was a ghetto.

In the spring of 1941 in preparation for the attack on the Soviet lines in eastern Poland the German military storage facilities were set up in Izbica, and kept under heavy guard.
 The first mass deportation of ghetto inmates to the Bełżec extermination camp took place in mid-March 1942 conducted by the Reserve Police Battalion 101 with the aid of Ukrainian Trawnikis.
During Operation Reinhard the ghetto served as a transfer point to the extermination camps in Bełżec and Sobibór for foreign Jews deported from Germany, Austria, Czechoslovakia and western Poland (Reichsgau Wartheland).
In rounding them up in Izbica, typically the guards murdered dozens or hundreds in the town.
Following the departures, Jews were hunted down and murdered in hiding places or in nearby fields.
More than 20,000 Jews passed through the Izbica ghetto.
Of all Jews of Izbica (over 90% of its prewar population), only 14 survived the Holocaust.
Following Poland's return to independence in the aftermath of World War I, the town grew significantly. Streets were paved and the marketplace rebuilt. According to 1921 census, Izbica had 3,085 inhabitants including 2,862 Jews, but by 1939, the total number grew to roughly 6,000 with 5,098 Jews. Izbica expanded particularly well because of the paved Lublin-Zamość thoroughfare, and a railway line to Zamość inaugurated in 1917.
Following the German and Soviet invasion of Poland in 1939 during the opening stages of World War II the town was overrun by the Nazis. A number of prominent Polish Christians were arrested and murdered in the course of the AB Action against Polish intelligentsia.   Jews were brutalized and robbed from the beginning of the occupation. The Germans resettled thousands of other Jews in Izbica beginning at the end of 1939.  These included deportees from Biała Podlaska, Komarówka, Wohyń, and Czemierniki arrived. Almost the entire town was a ghetto.
In the spring of 1941 in preparation for the attack on the Soviet lines in eastern Poland the German military storage facilities were set up in Izbica, and kept under heavy guard.  The first mass deportation of ghetto inmates to the Bełżec extermination camp took place in mid-March 1942 conducted by the Reserve Police Battalion 101 with the aid of Ukrainian Trawnikis. During Operation Reinhard the ghetto served as a transfer point to the extermination camps in Bełżec and Sobibór for foreign Jews deported from Germany, Austria, Czechoslovakia and western Poland (Reichsgau Wartheland). In rounding them up in Izbica, typically the guards murdered dozens or hundreds in the town. Following the departures, Jews were hunted down and murdered in hiding places or in nearby fields. More than 20,000 Jews passed through the Izbica ghetto. Of all Jews of Izbica (over 90% of its prewar population), only 14 survived the Holocaust.
Izbica