In June 2011, Ramirez got engaged to their longtime partner, Ryan DeBolt, a business analyst at TIMEC in Paris, France.
They were married on July 4, 2012, in a private beachside ceremony in New York.

In September 2016, Ramirez donated their hair to Locks of Love, an organization that makes wigs for children who suffer from medical conditions that lead to hair loss.
Afterward, they sported a buzz cut, styled as an undercut.

In October 2016, Ramirez came out as queer and bisexual at the True Colors Fund's "40 To None Summit" (now known as the "Impact Summit") in Los Angeles, California.
In an email to The Huffington Post, they wrote that their decision to come out publicly was a "very organic and natural" one.
In August 2020, Ramirez came out as non-binary on social media and stated that their pronouns are she or they.
In June 2011, Ramirez got engaged to their longtime partner, Ryan DeBolt, a business analyst at TIMEC in Paris, France. They were married on July 4, 2012, in a private beachside ceremony in New York. 
In September 2016, Ramirez donated their hair to Locks of Love, an organization that makes wigs for children who suffer from medical conditions that lead to hair loss. Afterward, they sported a buzz cut, styled as an undercut.
In October 2016, Ramirez came out as queer and bisexual at the True Colors Fund's "40 To None Summit" (now known as the "Impact Summit") in Los Angeles, California. In an email to The Huffington Post, they wrote that their decision to come out publicly was a "very organic and natural" one. In August 2020, Ramirez came out as non-binary on social media and stated that their pronouns are she or they.
Sara Ramirez