The Cira Centre on the Schuylkill River, designed by Pelli, opened in January 2006.
Pelli designed the master plan for Cira Centre South, the tallest building dedicated to student housing in the United States.
The building houses students of the University of Pennsylvania and was completed in 2014.
He was also architect of the 730-foot luxury mixed-use skyscraper FMC Tower as part of the Cira Centre South development.

This period saw the completion of several cultural/civic projects designed by Pelli.
The Adrienne Arsht Center for the Performing Arts in Miami, Florida, opened in 2006, the same year that Pelli's design for the Minneapolis Central Library completed construction, as well as the Renee and Henry Segerstrom Concert Hall and Samueli Theater in Costa Mesa, California.
 Pelli designs for office towers and developments throughout Asia and South America have been completed in the past decade.
In 2012, the three-building Pacific Design Center, which Pelli designed 40 years earlier while at Gruen Associates, was completed with the addition of the Red Building.

In May 2008, Pelli was given an honorary Doctor of Arts degree by Yale University.
That same year, he received the Lynn S. Beedle Lifetime Achievement Award from the Council on Tall Buildings and Urban Habitat (CTBUH).
In 2012, Pelli was honored with the platinum Konex Award for architecture and the diamond Konex Award for visual arts.

Major projects completed in the 2010s included The Landmark in Abu Dhabi and Sevilla Tower in Seville, Spain.
 In 2018, the Salesforce Tower and the first phase of the adjacent Transbay Transit Center in San Francisco were completed.
 The Salesforce Tower was named the world's best tall building by CTBUH in 2019 which is the year when Pelli died.
The Cira Centre on the Schuylkill River, designed by Pelli, opened in January 2006. Pelli designed the master plan for Cira Centre South, the tallest building dedicated to student housing in the United States. The building houses students of the University of Pennsylvania and was completed in 2014. He was also architect of the 730-foot luxury mixed-use skyscraper FMC Tower as part of the Cira Centre South development.
This period saw the completion of several cultural/civic projects designed by Pelli. The Adrienne Arsht Center for the Performing Arts in Miami, Florida, opened in 2006, the same year that Pelli's design for the Minneapolis Central Library completed construction, as well as the Renee and Henry Segerstrom Concert Hall and Samueli Theater in Costa Mesa, California.  Pelli designs for office towers and developments throughout Asia and South America have been completed in the past decade. In 2012, the three-building Pacific Design Center, which Pelli designed 40 years earlier while at Gruen Associates, was completed with the addition of the Red Building.
In May 2008, Pelli was given an honorary Doctor of Arts degree by Yale University. That same year, he received the Lynn S. Beedle Lifetime Achievement Award from the Council on Tall Buildings and Urban Habitat (CTBUH). In 2012, Pelli was honored with the platinum Konex Award for architecture and the diamond Konex Award for visual arts.
Major projects completed in the 2010s included The Landmark in Abu Dhabi and Sevilla Tower in Seville, Spain.  In 2018, the Salesforce Tower and the first phase of the adjacent Transbay Transit Center in San Francisco were completed.  The Salesforce Tower was named the world's best tall building by CTBUH in 2019 which is the year when Pelli died.
César Pelli