The work lists thirty-five authors in addition to the editor, who was also the author of the unsigned articles.
The other authors were classical scholars, primarily from Oxford, Cambridge, Rugby School, and the University of Bonn, but some were from other institutions.
Many of the mythological entries were the work of the German expatriate Leonhard Schmitz, who helped to popularise German classical scholarship in Britain.


With respect to biographies, Smith intended to be comprehensive.
In the preface, he writes:
The biographical articles in this work include the names of all persons of any importance which occur in the Greek and Roman writers, from the earliest times down to the extinction of the Western Empire in the year 476 of our era, and to the extinction of the Eastern Empire by the capture of Constantinople by the Turks in the year 1453.

Much of the value of the Dictionary consists not only in the depth and detail of the individual articles, but in the copious and specific citations to individual Greek and Roman writers, as well as modern scholarship from the Renaissance to the mid-nineteenth century.
 The articles frequently note variant traditions, disagreements among the authorities, and the interpretations of modern scholars.
 However, due to the variable numbering systems used in different editions of classical works, and the difficulty of recognizing typographical errors in citations, the original sources should still be checked.
 Many of the Dictionary's articles have been referred to in more recent works, and Robert Graves has been accused of "lifting his impressive-looking source references straight, and unchecked" from it when writing The Greek Myths.

Samuel Sharpe thought Edward Bunbury had plagiarised his work, as he wrote of in his diary entry on 3 September 1850: 
I certainly felt mortified on reading the articles on the Ptolemies in Dr. Smith's "Dictionary of Classical Biography."
They were all written by E. H. Bunbury with the help of my "History of Egypt," and with-out any acknowledgment, though he even borrowed the volume from my brother Dan for the purpose.
The work lists thirty-five authors in addition to the editor, who was also the author of the unsigned articles. The other authors were classical scholars, primarily from Oxford, Cambridge, Rugby School, and the University of Bonn, but some were from other institutions. Many of the mythological entries were the work of the German expatriate Leonhard Schmitz, who helped to popularise German classical scholarship in Britain.

With respect to biographies, Smith intended to be comprehensive. In the preface, he writes:
The biographical articles in this work include the names of all persons of any importance which occur in the Greek and Roman writers, from the earliest times down to the extinction of the Western Empire in the year 476 of our era, and to the extinction of the Eastern Empire by the capture of Constantinople by the Turks in the year 1453.
Much of the value of the Dictionary consists not only in the depth and detail of the individual articles, but in the copious and specific citations to individual Greek and Roman writers, as well as modern scholarship from the Renaissance to the mid-nineteenth century.  The articles frequently note variant traditions, disagreements among the authorities, and the interpretations of modern scholars.  However, due to the variable numbering systems used in different editions of classical works, and the difficulty of recognizing typographical errors in citations, the original sources should still be checked.  Many of the Dictionary's articles have been referred to in more recent works, and Robert Graves has been accused of "lifting his impressive-looking source references straight, and unchecked" from it when writing The Greek Myths.
Samuel Sharpe thought Edward Bunbury had plagiarised his work, as he wrote of in his diary entry on 3 September 1850: 
I certainly felt mortified on reading the articles on the Ptolemies in Dr. Smith's "Dictionary of Classical Biography." They were all written by E. H. Bunbury with the help of my "History of Egypt," and with-out any acknowledgment, though he even borrowed the volume from my brother Dan for the purpose.
Dictionary of Greek and Roman Biography and Mythology