On 9 April 1839, Senhouse commissioned HMS Blenheim.
He was sent from England to fill the office of second-in-command of British naval forces in China, where he served in the First Anglo-Chinese War.
Commodore Gordon Bremer, commander-in-chief of British forces, entrusted the attack on Anunghoy Island to Senhouse in the capture of the Bogue forts on 26 February 1841.
After the Blenheim fired broadsides from starboard at the island's fort, Senhouse landed with about 300 marines and seamen to clear the few remaining defenders.
On 31 March, Bremer sailed to Calcutta in the steamer Queen to confer with Lord Auckland about the state of affairs and request reinforcements, leaving Senhouse in command of the naval forces.

On 13 June 1841, Senhouse died on board the Blenheim in Hong Kong from fever contracted during the operations in Canton in May 1841.
As the next senior naval officer, Captain Thomas Herbert took over command of the ship and fleet.
Duncan MacPherson of the Madras Army wrote, "On the morning of the 13th of June, when it was announced to him [Senhouse] that all hopes of saving his life was at an end, he immediately directed that the signal be made for all captains of H. M.'s ships to repair on board; but ere the first had arrived, our gallant commodore was a corpse."

Before he died, he wished to be interred in Macao because of uncertainty about Hong Kong's future as a British settlement.
The steamship Nemesis arrived with his body in Macao on 16 June.
The next morning, a funeral procession began from Captain Charles Elliot's house.
Major-General Hugh Gough, Captain Herbert, Deputy Superintendent of Trade Alexander Johnston, at least 70 military officers, and nearly all the British and foreign residents were in attendance.
Also present was the Portuguese governor of Macau, his band who played the funeral march, and a contingent of Portuguese troops who fired three volleys over his grave at the Old Protestant Cemetery.

On 29 June, Senhouse was nominated a Companion of the Most Honourable Military Order of the Bath.
A bell that he captured in the Bogue forts was sent to England by Captain John Charles Pitman in HMS Druid.
It was donated to St Mary's Church in Gosforth by Senhouse's widow in 1844.
On 9 April 1839, Senhouse commissioned HMS Blenheim. He was sent from England to fill the office of second-in-command of British naval forces in China, where he served in the First Anglo-Chinese War. Commodore Gordon Bremer, commander-in-chief of British forces, entrusted the attack on Anunghoy Island to Senhouse in the capture of the Bogue forts on 26 February 1841. After the Blenheim fired broadsides from starboard at the island's fort, Senhouse landed with about 300 marines and seamen to clear the few remaining defenders. On 31 March, Bremer sailed to Calcutta in the steamer Queen to confer with Lord Auckland about the state of affairs and request reinforcements, leaving Senhouse in command of the naval forces.
On 13 June 1841, Senhouse died on board the Blenheim in Hong Kong from fever contracted during the operations in Canton in May 1841. As the next senior naval officer, Captain Thomas Herbert took over command of the ship and fleet. Duncan MacPherson of the Madras Army wrote, "On the morning of the 13th of June, when it was announced to him [Senhouse] that all hopes of saving his life was at an end, he immediately directed that the signal be made for all captains of H. M.'s ships to repair on board; but ere the first had arrived, our gallant commodore was a corpse."
Before he died, he wished to be interred in Macao because of uncertainty about Hong Kong's future as a British settlement. The steamship Nemesis arrived with his body in Macao on 16 June. The next morning, a funeral procession began from Captain Charles Elliot's house. Major-General Hugh Gough, Captain Herbert, Deputy Superintendent of Trade Alexander Johnston, at least 70 military officers, and nearly all the British and foreign residents were in attendance. Also present was the Portuguese governor of Macau, his band who played the funeral march, and a contingent of Portuguese troops who fired three volleys over his grave at the Old Protestant Cemetery.
On 29 June, Senhouse was nominated a Companion of the Most Honourable Military Order of the Bath. A bell that he captured in the Bogue forts was sent to England by Captain John Charles Pitman in HMS Druid. It was donated to St Mary's Church in Gosforth by Senhouse's widow in 1844.
Humphrey Fleming Senhouse