In August 2006 Lamb of God released its fifth studio album, Sacrament.
The album debuted at number eight on the Billboard 200 and sold nearly 65,000 copies in its first week of sales, nearly doubling the first week sales of Ashes of the Wake.
The album received generally positive reviews, with Cosmo Lee of Stylus Magazine stating, "Sacrament has the band's most memorable songs to date.
Musically, there's no fat.
The band plays with laser precision and songs move smoothly through riffs and transitions."
Ed Thompson of IGN referred to Sacrament "one of the best metal albums of 2006", and Jon Pareles of Blender called it a "speed rush all the way through".
Sacrament would become the band's second gold record issued by the RIAA in September 2019.

The band appeared on major tours to support the album, including The Unholy Alliance with Slayer, Mastodon, Children of Bodom, and Thine Eyes Bleed, Gigantour, supporting Megadeth; main stage at Ozzfest; an appearance at the Download Festival, and an exclusive co-headlining tour with Killswitch Engage, Soilwork, and DevilDriver, where Killswitch Engage and Lamb of God shared headlining spots alternately each show.
Lamb of God was nominated for Best Metal Performance at the 2007 Grammy Awards for "Redneck", but lost out to Slayer's "Eyes of the Insane".

In December 2007, the band rereleased the album as Sacrament: Deluxe Producer Edition.
The release contained all of the original songs from Sacrament on the first disc, and the second disc was a CD-ROM featuring all of the vocal, bass, guitar, and drum tracks in 192kbit/s MP3 format, enabling the buyer to produce their own interpretation of the songs.
Blythe stated, "you sometimes have to do something special to get kids to even buy an album these days rather than download it."
The band took a break to write new material throughout 2008 and prepare a new record for release, slated for 2009.
The band negotiated for a new record label to distribute records outside the United States.
Chris Adler stated Epic Records in the United States "couldn't be more perfect", but wants a different label for international releases.

In spite of the success of the tour, the band was not without at least one serious altercation which has since been widely publicized.
After playing a sell-out show in Glasgow, Scotland, members of the band and crew were involved in heavy drinking.
After a brief amount of time, vocalist Randy Blythe, whilst wearing a kilt and attempting to speak with a Scottish accent, became verbally violent towards both drummer Chris Adler and guitarist Mark Morton, the latter of whom then struck Blythe from behind on the bus in response.
The incident developed into grabbing, pushing and separating until Blythe and Morton then encountered each other outside on the footpath.
The fight between the two was especially lackluster due to intoxication, however it resulted in Morton bringing Blythe down hard on the pavement beneath him briefly incapacitating Blythe.
Two days and at least one show later, the duo reconciled over drinks.
In August 2006 Lamb of God released its fifth studio album, Sacrament. The album debuted at number eight on the Billboard 200 and sold nearly 65,000 copies in its first week of sales, nearly doubling the first week sales of Ashes of the Wake. The album received generally positive reviews, with Cosmo Lee of Stylus Magazine stating, "Sacrament has the band's most memorable songs to date. Musically, there's no fat. The band plays with laser precision and songs move smoothly through riffs and transitions." Ed Thompson of IGN referred to Sacrament "one of the best metal albums of 2006", and Jon Pareles of Blender called it a "speed rush all the way through". Sacrament would become the band's second gold record issued by the RIAA in September 2019.
The band appeared on major tours to support the album, including The Unholy Alliance with Slayer, Mastodon, Children of Bodom, and Thine Eyes Bleed, Gigantour, supporting Megadeth; main stage at Ozzfest; an appearance at the Download Festival, and an exclusive co-headlining tour with Killswitch Engage, Soilwork, and DevilDriver, where Killswitch Engage and Lamb of God shared headlining spots alternately each show. Lamb of God was nominated for Best Metal Performance at the 2007 Grammy Awards for "Redneck", but lost out to Slayer's "Eyes of the Insane".
In December 2007, the band rereleased the album as Sacrament: Deluxe Producer Edition. The release contained all of the original songs from Sacrament on the first disc, and the second disc was a CD-ROM featuring all of the vocal, bass, guitar, and drum tracks in 192kbit/s MP3 format, enabling the buyer to produce their own interpretation of the songs. Blythe stated, "you sometimes have to do something special to get kids to even buy an album these days rather than download it." The band took a break to write new material throughout 2008 and prepare a new record for release, slated for 2009. The band negotiated for a new record label to distribute records outside the United States. Chris Adler stated Epic Records in the United States "couldn't be more perfect", but wants a different label for international releases.
In spite of the success of the tour, the band was not without at least one serious altercation which has since been widely publicized. After playing a sell-out show in Glasgow, Scotland, members of the band and crew were involved in heavy drinking. After a brief amount of time, vocalist Randy Blythe, whilst wearing a kilt and attempting to speak with a Scottish accent, became verbally violent towards both drummer Chris Adler and guitarist Mark Morton, the latter of whom then struck Blythe from behind on the bus in response. The incident developed into grabbing, pushing and separating until Blythe and Morton then encountered each other outside on the footpath. The fight between the two was especially lackluster due to intoxication, however it resulted in Morton bringing Blythe down hard on the pavement beneath him briefly incapacitating Blythe. Two days and at least one show later, the duo reconciled over drinks.
Lamb of God (band)