In 1866, permission was given to local landowners for a Hounslow and Metropolitan Railway, which would serve areas in Hounslow such as Boston Manor, and to connect to another proposed line called the Acton & Brentford railway.
However, the latter was never constructed but instead a 5 ¹⁄₂-mile-long (8.9 km) extension of the District Railway (DR) from Mill Hill Park (now Acton Town) to Hounslow Barracks (now Hounslow West) was considered and granted.

Boston Manor was initially opened by the DR on 1 May 1883 as part of an extension from Mill Hill Park to Hounslow Town.
The station was originally named Boston Road.
The signs on the platforms gave the name as Boston Manor for Brentford & Hanwell.
Electrification of the DR's tracks took place between 1903 and 1905 with electric trains replacing steam trains on the Hounslow branch from 13 June 1905.
Northfields (Ealing) Halt (now Northfields), the next stop to the east was only opened on 16 April 1908.
The station was given its current name on 11 December 1911.

To prepare for the Piccadilly line extension to Hounslow, the station was rebuilt between 1932 and 1934 in a Modernist style which replaced the 1883 station building.
During the reconstruction, a temporary booking hall was built.
Piccadilly line services, which had been running as far as Northfields since 9 January 1933 were extended to run to Hounslow West on 13 March 1933 when the partially completed Boston Manor station was opened to passengers.
The new station building was finally completed on 25 March 1934.

Because of the Piccadilly line extension, off-peak District line services through the station was converted to a Hounslow West to South Acton shuttle.
This was discontinued on 29 April 1935 while peak hour services were withdrawn completely on 9 October 1964.

In 2018, it was announced that the station would gain step-free access by 2022, as part of a £200m investment to increase the number of accessible stations on the network.
In 1866, permission was given to local landowners for a Hounslow and Metropolitan Railway, which would serve areas in Hounslow such as Boston Manor, and to connect to another proposed line called the Acton & Brentford railway. However, the latter was never constructed but instead a 5 ¹⁄₂-mile-long (8.9 km) extension of the District Railway (DR) from Mill Hill Park (now Acton Town) to Hounslow Barracks (now Hounslow West) was considered and granted.
Boston Manor was initially opened by the DR on 1 May 1883 as part of an extension from Mill Hill Park to Hounslow Town. The station was originally named Boston Road. The signs on the platforms gave the name as Boston Manor for Brentford & Hanwell. Electrification of the DR's tracks took place between 1903 and 1905 with electric trains replacing steam trains on the Hounslow branch from 13 June 1905. Northfields (Ealing) Halt (now Northfields), the next stop to the east was only opened on 16 April 1908. The station was given its current name on 11 December 1911.
To prepare for the Piccadilly line extension to Hounslow, the station was rebuilt between 1932 and 1934 in a Modernist style which replaced the 1883 station building. During the reconstruction, a temporary booking hall was built. Piccadilly line services, which had been running as far as Northfields since 9 January 1933 were extended to run to Hounslow West on 13 March 1933 when the partially completed Boston Manor station was opened to passengers. The new station building was finally completed on 25 March 1934.
Because of the Piccadilly line extension, off-peak District line services through the station was converted to a Hounslow West to South Acton shuttle. This was discontinued on 29 April 1935 while peak hour services were withdrawn completely on 9 October 1964.
In 2018, it was announced that the station would gain step-free access by 2022, as part of a £200m investment to increase the number of accessible stations on the network.
Boston Manor tube station