The regiment, which was named after Prince Albert Edward, the future King Edward VII, was raised in Canada, to create extra military resources following the Indian Rebellion, in June 1858.
It embarked for England later that year and was posted to Gibraltar in 1863 but moved to Malta later in the year.
It returned to Canada in 1866 and took part in the ceremony for the inauguration of the Dominion of Canada on 1 July 1867, before returning to England in 1868.

In 1875 it was declared the successor to the 100th Regiment of Foot (Prince Regent's County of Dublin Regiment), which had served in Canada, and allowed to use the battle honour "Niagara".
It embarked for Bengal in India in 1877.

As part of the Cardwell Reforms of the 1870s, where single-battalion regiments were linked together to share a single depot and recruiting district in the United Kingdom, the 100th was linked with the 109th Regiment of Foot (Bombay Infantry), and assigned to district no.
67 at Crinkill Barracks in Birr, County Offaly.
On 1 July 1881 the Childers Reforms came into effect and the regiment amalgamated with the 109th Regiment of Foot (Bombay Infantry) to form the Prince of Wales's Leinster Regiment (Royal Canadians).
The regiment, which was named after Prince Albert Edward, the future King Edward VII, was raised in Canada, to create extra military resources following the Indian Rebellion, in June 1858. It embarked for England later that year and was posted to Gibraltar in 1863 but moved to Malta later in the year. It returned to Canada in 1866 and took part in the ceremony for the inauguration of the Dominion of Canada on 1 July 1867, before returning to England in 1868.
In 1875 it was declared the successor to the 100th Regiment of Foot (Prince Regent's County of Dublin Regiment), which had served in Canada, and allowed to use the battle honour "Niagara". It embarked for Bengal in India in 1877.
As part of the Cardwell Reforms of the 1870s, where single-battalion regiments were linked together to share a single depot and recruiting district in the United Kingdom, the 100th was linked with the 109th Regiment of Foot (Bombay Infantry), and assigned to district no. 67 at Crinkill Barracks in Birr, County Offaly. On 1 July 1881 the Childers Reforms came into effect and the regiment amalgamated with the 109th Regiment of Foot (Bombay Infantry) to form the Prince of Wales's Leinster Regiment (Royal Canadians).
100th (Prince of Wales's Royal Canadian) Regiment of Foot