On March 1, 2011 the 49ers introduced Wake Forest defensive coordinator Brad Lambert as the program's first head coach.

The 49ers played as an Independent during their two years in the FCS subdivision.
Charlotte Football officially joined the FBS subdivision and C-USA Football on July 1, 2015.

On November 18, 2018, Charlotte Athletics Director Mike Hill announced that after 8 years and 6 seasons as head coach, Lambert would not be retained following the season.
Lambert had compiled a record of 22–48 during his tenure, including the program's first win in the inaugural game and winning the program's first FBS game.
Lambert would finish his career at Charlotte a week later with a season-ending road victory against the previous season conference champion FAU.
On March 1, 2011 the 49ers introduced Wake Forest defensive coordinator Brad Lambert as the program's first head coach.
The 49ers played as an Independent during their two years in the FCS subdivision. Charlotte Football officially joined the FBS subdivision and C-USA Football on July 1, 2015.
On November 18, 2018, Charlotte Athletics Director Mike Hill announced that after 8 years and 6 seasons as head coach, Lambert would not be retained following the season. Lambert had compiled a record of 22–48 during his tenure, including the program's first win in the inaugural game and winning the program's first FBS game. Lambert would finish his career at Charlotte a week later with a season-ending road victory against the previous season conference champion FAU.
Charlotte 49ers football