King Arthur, supposedly buried in the Eildon Hills, which overlook the town
James Blair, recipient of the Victoria Cross
Craig Chalmers, rugby union footballer, capped 60 times for Scotland
Sir Adam Ferguson, army officer and Deputy Keeper of the Scottish Regalia lived at Huntlyburn House, now a wing of the Hospital.

Ned Haig, butcher and rugby union footballer who founded rugby sevens and the Melrose Sevens
John Robertson Henderson FRSE FZS FLS, zoologist
William Kerr, recipient of the Victoria Cross
Keith Robertson, rugby union footballer
Mark Robertson, son of Keith Robertson; rugby union sevens, 2016 Olympic silver medalist
Sir Walter Scott, his home Abbotsford House lies a few miles west of the town
Catherine Helen Spence (1825–1910), Australian author, teacher, journalist, politician and suffragette; born in Melrose, and left for Australia aged fourteen
Jim Telfer, rugby union footballer and coach
King Arthur, supposedly buried in the Eildon Hills, which overlook the town
James Blair, recipient of the Victoria Cross
Craig Chalmers, rugby union footballer, capped 60 times for Scotland
Sir Adam Ferguson, army officer and Deputy Keeper of the Scottish Regalia lived at Huntlyburn House, now a wing of the Hospital.
Ned Haig, butcher and rugby union footballer who founded rugby sevens and the Melrose Sevens
John Robertson Henderson FRSE FZS FLS, zoologist
William Kerr, recipient of the Victoria Cross
Keith Robertson, rugby union footballer
Mark Robertson, son of Keith Robertson; rugby union sevens, 2016 Olympic silver medalist
Sir Walter Scott, his home Abbotsford House lies a few miles west of the town
Catherine Helen Spence (1825–1910), Australian author, teacher, journalist, politician and suffragette; born in Melrose, and left for Australia aged fourteen
Jim Telfer, rugby union footballer and coach
Melrose, Scottish Borders