Seventeen sailors and marines assigned to VX-6 died in Antarctica in support of Operation Deep Freeze.

On 18 October 1956, a P2V-2 Neptune crashed at McMurdo Station during a landing in whiteout conditions, killing David W. Carey, Rayburn A. Hudman, Marion O. Marze, and Charles S. Miller.

On 12 July 1957, an HO4S-3 crashed in the vicinity of McMurdo Station during austral winter, killing Nelson R. Cole.

On 4 January 1959, a UC-1 Otter crashed on takeoff at Marble Point, killing Harvey E. Gardner and Lawrence J. Farrell.

On 9 November 1961, a P2V-7 crashed on takeoff from Wilkes Station, killing William D. Counts, Romuald P. Compton, William W. Chastain, James L. Gray and passenger geologist Dr. Edward C. Thiel.

On 2 February 1966, a LC-47J crashed on Ross Ice Shelf during takeoff, killing Ronald Rosenthal, Harold M. Morris, William D. Fordell, Richard S. Simmons, Wayne M. Shattuck, and Charles C. Kelley.
Seventeen sailors and marines assigned to VX-6 died in Antarctica in support of Operation Deep Freeze.
On 18 October 1956, a P2V-2 Neptune crashed at McMurdo Station during a landing in whiteout conditions, killing David W. Carey, Rayburn A. Hudman, Marion O. Marze, and Charles S. Miller.
On 12 July 1957, an HO4S-3 crashed in the vicinity of McMurdo Station during austral winter, killing Nelson R. Cole.
On 4 January 1959, a UC-1 Otter crashed on takeoff at Marble Point, killing Harvey E. Gardner and Lawrence J. Farrell.
On 9 November 1961, a P2V-7 crashed on takeoff from Wilkes Station, killing William D. Counts, Romuald P. Compton, William W. Chastain, James L. Gray and passenger geologist Dr. Edward C. Thiel.
On 2 February 1966, a LC-47J crashed on Ross Ice Shelf during takeoff, killing Ronald Rosenthal, Harold M. Morris, William D. Fordell, Richard S. Simmons, Wayne M. Shattuck, and Charles C. Kelley.
VX-6