In 2001 Hancock recorded Future2Future, which reunited Hancock with Laswell and featured doses of electronica as well as turntablist Rob Swift of The X-Ecutioners.
Hancock later toured with the band, and released a concert DVD with a different lineup, which also included the "Rockit" music video.
Also in 2001 Hancock partnered with Brecker and Roy Hargrove to record a live concert album saluting Davis and John Coltrane, entitled Directions in Music: Live at Massey Hall, recorded live in Toronto.
The threesome toured to support the album, and toured on-and-off through 2005.

The year 2005 saw the release of a duet album called Possibilities.
It featured duets with Carlos Santana, Paul Simon, Annie Lennox, John Mayer, Christina Aguilera, Sting and others.
In 2006 Possibilities was nominated for Grammy Awards in two categories: "A Song for You" (featuring Aguilera) was nominated for a Grammy Award for Best Pop Instrumental Performance, and "Gelo No Montanha" (featuring Trey Anastasio on guitar) was nominated for a Grammy Award for Best Instrumental Performance, although neither nomination resulted in an award.

Also in 2005 Hancock toured Europe with a new quartet that included Beninese guitarist Lionel Loueke, and explored textures ranging from ambient to straight jazz to African music.
Plus, during the summer of 2005, Hancock re-staffed the Headhunters and went on tour with them, including a performance at The Bonnaroo Music & Arts Festival.
This lineup did not consist of any of the original Headhunters musicians.
The group included Marcus Miller, Carrington, Loueke and Mayer.
Hancock also served as the first artist in residence for Bonnaroo that summer.

Also in 2006 Sony BMG Music Entertainment (which bought out Hancock's old label, Columbia Records) released the two-disc retrospective The Essential Herbie Hancock.
This set was the first compilation of his work at Warner Bros., Blue Note, Columbia and Verve/Polygram.
This became Hancock's second major compilation of work since the 2002 Columbia-only The Herbie Hancock Box, which was released at first in a plastic 4 × 4 cube then re-released in 2004 in a long box set.
Also in 2006, Hancock recorded a new song with Josh Groban and Eric Mouquet (co-founder of Deep Forest), entitled "Machine".
It is featured on Groban's CD Awake.
Hancock also recorded and improvised with guitarist Loueke on Loueke's 1996 debut album Virgin Forest, on the ObliqSound label, resulting in two improvisational tracks – "Le Réveil des agneaux (The Awakening of the Lambs)" and  "La Poursuite du lion (The Lion's Pursuit)".

Hancock, a longtime associate and friend of Mitchell, released a 2007 album, River: The Joni Letters, that paid tribute to her work, with Norah Jones and Tina Turner adding vocals to the album, as did Corinne Bailey Rae.
Leonard Cohen contributed a spoken piece set to Hancock's piano.
Mitchell herself also made an appearance.
The album was released on September 25, 2007, simultaneously with the release of Mitchell's newest album at that time: Shine.
River won the 2008 Album of the Year Grammy Award.
The album also won a Grammy for Best Contemporary Jazz Album, and the song "Both Sides Now" was nominated for Best Instrumental Jazz Solo.
That was only the second time in history that a jazz album had both those Grammys.

On June 14, 2008 Hancock performed with others at Rhythm on the Vine at the South Coast Winery in Temecula, California, for Shriners Hospitals for Children.
The event raised $515,000 for Shriners Hospital.

On January 18, 2009, Hancock performed at the We Are One concert, marking the start of inaugural celebrations for American President Barack Obama.
Hancock also performed Rhapsody in Blue at the 2009 Classical BRIT Awards with classical pianist Lang Lang.
Hancock was named as the Los Angeles Philharmonic's creative chair for jazz for 2010–12.
In 2001 Hancock recorded Future2Future, which reunited Hancock with Laswell and featured doses of electronica as well as turntablist Rob Swift of The X-Ecutioners. Hancock later toured with the band, and released a concert DVD with a different lineup, which also included the "Rockit" music video. Also in 2001 Hancock partnered with Brecker and Roy Hargrove to record a live concert album saluting Davis and John Coltrane, entitled Directions in Music: Live at Massey Hall, recorded live in Toronto. The threesome toured to support the album, and toured on-and-off through 2005.
The year 2005 saw the release of a duet album called Possibilities. It featured duets with Carlos Santana, Paul Simon, Annie Lennox, John Mayer, Christina Aguilera, Sting and others. In 2006 Possibilities was nominated for Grammy Awards in two categories: "A Song for You" (featuring Aguilera) was nominated for a Grammy Award for Best Pop Instrumental Performance, and "Gelo No Montanha" (featuring Trey Anastasio on guitar) was nominated for a Grammy Award for Best Instrumental Performance, although neither nomination resulted in an award.
Also in 2005 Hancock toured Europe with a new quartet that included Beninese guitarist Lionel Loueke, and explored textures ranging from ambient to straight jazz to African music. Plus, during the summer of 2005, Hancock re-staffed the Headhunters and went on tour with them, including a performance at The Bonnaroo Music & Arts Festival. This lineup did not consist of any of the original Headhunters musicians. The group included Marcus Miller, Carrington, Loueke and Mayer. Hancock also served as the first artist in residence for Bonnaroo that summer.
Also in 2006 Sony BMG Music Entertainment (which bought out Hancock's old label, Columbia Records) released the two-disc retrospective The Essential Herbie Hancock. This set was the first compilation of his work at Warner Bros., Blue Note, Columbia and Verve/Polygram. This became Hancock's second major compilation of work since the 2002 Columbia-only The Herbie Hancock Box, which was released at first in a plastic 4 × 4 cube then re-released in 2004 in a long box set. Also in 2006, Hancock recorded a new song with Josh Groban and Eric Mouquet (co-founder of Deep Forest), entitled "Machine". It is featured on Groban's CD Awake. Hancock also recorded and improvised with guitarist Loueke on Loueke's 1996 debut album Virgin Forest, on the ObliqSound label, resulting in two improvisational tracks – "Le Réveil des agneaux (The Awakening of the Lambs)" and  "La Poursuite du lion (The Lion's Pursuit)".
Hancock, a longtime associate and friend of Mitchell, released a 2007 album, River: The Joni Letters, that paid tribute to her work, with Norah Jones and Tina Turner adding vocals to the album, as did Corinne Bailey Rae. Leonard Cohen contributed a spoken piece set to Hancock's piano. Mitchell herself also made an appearance. The album was released on September 25, 2007, simultaneously with the release of Mitchell's newest album at that time: Shine. River won the 2008 Album of the Year Grammy Award. The album also won a Grammy for Best Contemporary Jazz Album, and the song "Both Sides Now" was nominated for Best Instrumental Jazz Solo. That was only the second time in history that a jazz album had both those Grammys.
On June 14, 2008 Hancock performed with others at Rhythm on the Vine at the South Coast Winery in Temecula, California, for Shriners Hospitals for Children. The event raised $515,000 for Shriners Hospital.
On January 18, 2009, Hancock performed at the We Are One concert, marking the start of inaugural celebrations for American President Barack Obama. Hancock also performed Rhapsody in Blue at the 2009 Classical BRIT Awards with classical pianist Lang Lang. Hancock was named as the Los Angeles Philharmonic's creative chair for jazz for 2010–12.
Herbie Hancock