(E)-Stilbene itself is of little value, but it is a precursor to other derivatives used as dyes, optical brighteners, phosphors, and scintillators.
Stilbene is one of the gain mediums used in dye lasers.

Disodium 4,4'-dinitrostilbene-2,2'-disulfonate is prepared by the sulfonation  of 4-nitrotoluene to form 4-nitrotoluene-2-sulfonic acid, which can then be oxidatively coupled using sodium hypochlorite to form the (E)-stilbene derivative in a process originally developed by Arthur Green and André Wahl in the late nineteenth century.
 Improvements to the process with higher yields have been developed, using air oxidation in liquid ammonia.
 The product is useful as its reaction with aniline derivatives results in the formation of azo dyes.
 Commercially important dyes derived from this compound include Direct Red 76, Direct Brown 78, and Direct Orange 40.

The stilbenoids are naturally occurring stilbene derivatives.
Examples include resveratrol and its cousin, pterostilbene.
 The stilbestrols, which are structurally but not synthetically related to (E)-stilbene, exhibit estrogenic activity.
 Members of this group include diethylstilbestrol, fosfestrol, and dienestrol.
(E)-Stilbene itself is of little value, but it is a precursor to other derivatives used as dyes, optical brighteners, phosphors, and scintillators. Stilbene is one of the gain mediums used in dye lasers.
Disodium 4,4'-dinitrostilbene-2,2'-disulfonate is prepared by the sulfonation  of 4-nitrotoluene to form 4-nitrotoluene-2-sulfonic acid, which can then be oxidatively coupled using sodium hypochlorite to form the (E)-stilbene derivative in a process originally developed by Arthur Green and André Wahl in the late nineteenth century.  Improvements to the process with higher yields have been developed, using air oxidation in liquid ammonia.  The product is useful as its reaction with aniline derivatives results in the formation of azo dyes.  Commercially important dyes derived from this compound include Direct Red 76, Direct Brown 78, and Direct Orange 40.
The stilbenoids are naturally occurring stilbene derivatives. Examples include resveratrol and its cousin, pterostilbene.  The stilbestrols, which are structurally but not synthetically related to (E)-stilbene, exhibit estrogenic activity.  Members of this group include diethylstilbestrol, fosfestrol, and dienestrol.
(E)-Stilbene