Jones was drafted by the New York Giants in the first round with the sixth overall pick in the 2019 NFL Draft.

Jones made his professional debut on August 8, 2019, in the first preseason game against the interleague-rival New York Jets, where he completed all five of his passes for 67 yards and a touchdown.
Despite a stellar preseason, Jones was named the backup behind Eli Manning.
Jones played his first regular season game on September 8, 2019, against the Dallas Cowboys in relief of Manning, where he completed 3-of-4 passes for 17 yards and lost a fumble as the Giants lost 35–17.
On September 17, 2019, Jones was named the starter over Manning for the Week 3 matchup against the Tampa Bay Buccaneers.
In his first start, Jones completed 23 out of 36 passes for 336 yards with a 112.7 passer rating and two passing touchdowns along with 28 rushing yards and two rushing touchdowns in a 32–31 comeback win against the Buccaneers despite losing two fumbles.
He became the first Giants' rookie quarterback to win his first career start since Scott Brunner in 1980.
Jones led the Giants back from an 18-point deficit to beat the Buccaneers and became the seventh rookie quarterback in NFL history since 2010 to have a game-winning drive in their first career start.
He was also named NFC Offensive Player of the Week for his performance in Week 3.
On September 29, in his second start (and first start at home), Jones led the Giants to a 24–3 victory over the Washington Redskins.
After the game, Jones became the third quarterback in the Giants' history after Phil Simms (1979) and Travis Tidwell (1950) to begin their career with two wins as a starting quarterback for the franchise.
Jones played his first game on prime time on Thursday Night Football in Week 6 against the New England Patriots.
In the game, Jones threw for 161 yards, one touchdown, and three interceptions in the 35–14 loss.
In Week 8, against the Detroit Lions, he had 322 passing yards and four passing touchdowns in a 31–26 defeat.
In Week 10 against the New York Jets, Jones threw for 308 yards and four touchdowns in the 34–27 loss.
In Week 16, Jones threw for career highs of 352 passing yards and five passing touchdowns as the Giants defeated the Washington Redskins in overtime 41–35.
In the process, Jones became the fifth quarterback in NFL history to throw five touchdown passes in a game as a rookie.
He also became the only rookie quarterback in NFL history to throw for 350 passing yards with five touchdowns and zero interceptions in a single game.
He was named the Pepsi Offensive Rookie of the Week for his efforts in the Week 16 win.
In Week 17 against the Philadelphia Eagles, Jones threw for 301 yards, one touchdown, and one interception during the 34–17 loss.
Jones finished his rookie season with 3,027 passing yards, 24 passing touchdowns, and 12 interceptions to go along with 45 carries for 279 rushing yards, two rushing touchdowns, and had a league-leading 18 fumbles with 11 of them lost.
Jones was drafted by the New York Giants in the first round with the sixth overall pick in the 2019 NFL Draft.
Jones made his professional debut on August 8, 2019, in the first preseason game against the interleague-rival New York Jets, where he completed all five of his passes for 67 yards and a touchdown. Despite a stellar preseason, Jones was named the backup behind Eli Manning. Jones played his first regular season game on September 8, 2019, against the Dallas Cowboys in relief of Manning, where he completed 3-of-4 passes for 17 yards and lost a fumble as the Giants lost 35–17. On September 17, 2019, Jones was named the starter over Manning for the Week 3 matchup against the Tampa Bay Buccaneers. In his first start, Jones completed 23 out of 36 passes for 336 yards with a 112.7 passer rating and two passing touchdowns along with 28 rushing yards and two rushing touchdowns in a 32–31 comeback win against the Buccaneers despite losing two fumbles. He became the first Giants' rookie quarterback to win his first career start since Scott Brunner in 1980. Jones led the Giants back from an 18-point deficit to beat the Buccaneers and became the seventh rookie quarterback in NFL history since 2010 to have a game-winning drive in their first career start. He was also named NFC Offensive Player of the Week for his performance in Week 3. On September 29, in his second start (and first start at home), Jones led the Giants to a 24–3 victory over the Washington Redskins. After the game, Jones became the third quarterback in the Giants' history after Phil Simms (1979) and Travis Tidwell (1950) to begin their career with two wins as a starting quarterback for the franchise. Jones played his first game on prime time on Thursday Night Football in Week 6 against the New England Patriots. In the game, Jones threw for 161 yards, one touchdown, and three interceptions in the 35–14 loss. In Week 8, against the Detroit Lions, he had 322 passing yards and four passing touchdowns in a 31–26 defeat. In Week 10 against the New York Jets, Jones threw for 308 yards and four touchdowns in the 34–27 loss. In Week 16, Jones threw for career highs of 352 passing yards and five passing touchdowns as the Giants defeated the Washington Redskins in overtime 41–35. In the process, Jones became the fifth quarterback in NFL history to throw five touchdown passes in a game as a rookie. He also became the only rookie quarterback in NFL history to throw for 350 passing yards with five touchdowns and zero interceptions in a single game. He was named the Pepsi Offensive Rookie of the Week for his efforts in the Week 16 win. In Week 17 against the Philadelphia Eagles, Jones threw for 301 yards, one touchdown, and one interception during the 34–17 loss. Jones finished his rookie season with 3,027 passing yards, 24 passing touchdowns, and 12 interceptions to go along with 45 carries for 279 rushing yards, two rushing touchdowns, and had a league-leading 18 fumbles with 11 of them lost.
Daniel Jones (American football)