On 1 September 1868, the Bergisch-Märkische Railway Company (Bergisch-Märkische Eisenbahn-Gesellschaft) opened the first section of the Rittershausen–Opladen line from Oberbarmen (then called Rittershausen) to Lennep, together with a branch line to Remscheid, giving the city its first rail connection.
Remscheid station (now called Remscheid Hauptbahnhof) and its attached buildings were built of timber.

A branch line to Hasten was opened on 1 September 1883, and the Lennep–Remscheid line was duplicated up to 1891.
Five years later, a branch to Bliedinghausen was added, but has only ever been used for freight.

As part of the construction of the line to Bliedinghausen the platforms were modified.
Passenger trains to Hasten previously ran from their own terminal platform west of the station building.
The sidings located east of Bismarckstraße later became the Remscheid East yard, which was connected to the station by a four track bridge over Bismarckstraße in 1900.

During the construction of the connecting line to Solingen via Güldenwerth over the Müngsten Bridge the locomotive depot was closed due to lack of space in early 1896 and locomotive maintenance was transferred to the depot in nearby Lennep.

In 1897 the gap between Solingen Süd and Remscheid was finally closed and in 1907 the route was duplicated.
Thus Remscheid station now had rail connections in four directions (and also via Lennep towards Opladen).
On 10 August 1911, a formal station building made of stone was inaugurated, replacing the existing building, which was called the Zigarrenkiste ("cigar box") because of its limited space.
The line to Hasten ended again at a bay platform to the west of the station building.
The main two tracks ran between a central platform and a "home" platform (next to the station building), connected by a pedestrian bridge and a tunnel for the railway post office.
The new building included a rebuilt section of the hall of Elberfeld-Döppersberg station (which was closed in 1848 when Wuppertal Hauptbahnhof opened).
Freight operations were moved in 1911 to the southern side of the station’s track field.

Until 1911, the station forecourt was called An der Quatsche; it was called Adolf Müller-Strasse during the Third Reich.

In 1914, Remscheid station was renamed Remscheid Hauptbahnhof to emphasise its importance as the most important station in the city of Remscheid.
In 1922 passenger services to Hasten were discontinued.
Freight traffic continued with general freight traffic to Hasten and Vieringhausen freight yards as well as wagon-load traffic to ten sidings of industrial enterprises.
Freight operations closed to Hasten in 1986 and to Vieringhausen in 1988; the line was officially closed on 31 December 1990.
The line was dismantled between March 1993 and September 1996.
In 2006 the line was reconstructed as the Trasse des Werkzeugs ("tool path").

The importance of Remscheid station was always less than the nearby Lennep station, which became the most important station when Lennep was incorporated into Remscheid in 1929.

On 28 April 1974, centralised interlocking was opened at the southwestern end of the railway land next to the Papenberger Straße level crossing.
On 1 September 1868, the Bergisch-Märkische Railway Company (Bergisch-Märkische Eisenbahn-Gesellschaft) opened the first section of the Rittershausen–Opladen line from Oberbarmen (then called Rittershausen) to Lennep, together with a branch line to Remscheid, giving the city its first rail connection. Remscheid station (now called Remscheid Hauptbahnhof) and its attached buildings were built of timber.
A branch line to Hasten was opened on 1 September 1883, and the Lennep–Remscheid line was duplicated up to 1891. Five years later, a branch to Bliedinghausen was added, but has only ever been used for freight.
As part of the construction of the line to Bliedinghausen the platforms were modified. Passenger trains to Hasten previously ran from their own terminal platform west of the station building. The sidings located east of Bismarckstraße later became the Remscheid East yard, which was connected to the station by a four track bridge over Bismarckstraße in 1900.
During the construction of the connecting line to Solingen via Güldenwerth over the Müngsten Bridge the locomotive depot was closed due to lack of space in early 1896 and locomotive maintenance was transferred to the depot in nearby Lennep.
In 1897 the gap between Solingen Süd and Remscheid was finally closed and in 1907 the route was duplicated. Thus Remscheid station now had rail connections in four directions (and also via Lennep towards Opladen). On 10 August 1911, a formal station building made of stone was inaugurated, replacing the existing building, which was called the Zigarrenkiste ("cigar box") because of its limited space. The line to Hasten ended again at a bay platform to the west of the station building. The main two tracks ran between a central platform and a "home" platform (next to the station building), connected by a pedestrian bridge and a tunnel for the railway post office. The new building included a rebuilt section of the hall of Elberfeld-Döppersberg station (which was closed in 1848 when Wuppertal Hauptbahnhof opened). Freight operations were moved in 1911 to the southern side of the station’s track field.
Until 1911, the station forecourt was called An der Quatsche; it was called Adolf Müller-Strasse during the Third Reich.
In 1914, Remscheid station was renamed Remscheid Hauptbahnhof to emphasise its importance as the most important station in the city of Remscheid. In 1922 passenger services to Hasten were discontinued. Freight traffic continued with general freight traffic to Hasten and Vieringhausen freight yards as well as wagon-load traffic to ten sidings of industrial enterprises. Freight operations closed to Hasten in 1986 and to Vieringhausen in 1988; the line was officially closed on 31 December 1990. The line was dismantled between March 1993 and September 1996. In 2006 the line was reconstructed as the Trasse des Werkzeugs ("tool path").
The importance of Remscheid station was always less than the nearby Lennep station, which became the most important station when Lennep was incorporated into Remscheid in 1929.
On 28 April 1974, centralised interlocking was opened at the southwestern end of the railway land next to the Papenberger Straße level crossing.
Remscheid Hauptbahnhof