On October 3, 1882, She married Lorillard Spencer Jr. (1860–1912), a son of Lorillard Spencer and Sarah (née Griswold) Spencer.
His paternal grandparents were Eleanora Eliza (née Lorillard) Spencer (daughter of Pierre Lorillard II) and William Augustus Spencer (son of U.S. Representative Ambrose Spencer and brother of John Canfield Spencer, the U.S. Secretary of War and Treasury).
 Among his siblings was sister, Eleanor Spencer (wife of Don Virginius Cenci, 6th Prince of Vicovaro) and brother William Augustus Spencer, who died aboard the RMS Titanic.
Together, they were the parents of several daughters who died in infancy, and a son:
Lorillard Suydam Spencer (1883–1939), who served as president of Atlantic Aircraft and married Mary Ridgeley Sands in 1905.
After their divorce in 1922, he married Katherine Emmons Force.

Lynette Suydam Spencer (1885–1887), who died young.

Nina Gladys Spencer (1888–1888), who died in infancy.

They had a home in Newport known as Chastellux, "one of the most beautiful places in that city."

After the death of her husband, who owned the Illustrated American, she became a missionary in the Philippines.

She died on April 6, 1948 at her home, Blue Bird Cottage, in Newport, Rhode Island.
She was buried in Green-Wood Cemetery in Brooklyn, New York.
On October 3, 1882, She married Lorillard Spencer Jr. (1860–1912), a son of Lorillard Spencer and Sarah (née Griswold) Spencer. His paternal grandparents were Eleanora Eliza (née Lorillard) Spencer (daughter of Pierre Lorillard II) and William Augustus Spencer (son of U.S. Representative Ambrose Spencer and brother of John Canfield Spencer, the U.S. Secretary of War and Treasury).  Among his siblings was sister, Eleanor Spencer (wife of Don Virginius Cenci, 6th Prince of Vicovaro) and brother William Augustus Spencer, who died aboard the RMS Titanic. Together, they were the parents of several daughters who died in infancy, and a son:
Lorillard Suydam Spencer (1883–1939), who served as president of Atlantic Aircraft and married Mary Ridgeley Sands in 1905. After their divorce in 1922, he married Katherine Emmons Force.
Lynette Suydam Spencer (1885–1887), who died young.
Nina Gladys Spencer (1888–1888), who died in infancy.
They had a home in Newport known as Chastellux, "one of the most beautiful places in that city."
After the death of her husband, who owned the Illustrated American, she became a missionary in the Philippines.
She died on April 6, 1948 at her home, Blue Bird Cottage, in Newport, Rhode Island. She was buried in Green-Wood Cemetery in Brooklyn, New York.
Caroline Berryman Spencer