After breaking up with Jeffrey Rubinoff, Radner had an on-again-off-again relationship with Martin Short while both were appearing in Godspell.

Radner had romantic involvements with several male Saturday Night Live castmates, including Bill Murray (after a previous relationship with his brother Brian Doyle-Murray) and Dan Aykroyd.
Radner's friend Judy Levy recounted Radner saying she found Ghostbusters hard to watch since the cast comprised so many of her ex-boyfriends - Aykroyd, Murray, and Harold Ramis.
Radner was first married to musician G. E. Smith after they met while working on Gilda Radner – Live from New York; they divorced in 1982.

Radner met actor Gene Wilder on the set of the Sidney Poitier film Hanky Panky (released in 1982), when the two worked together making the film.
She described their first meeting as "love at first sight".
After meeting Wilder, her marriage to Smith deteriorated.
Radner went on to make a second film with Wilder, The Woman in Red (released in 1984), and their relationship deepened further.
The two were married on September 18, 1984, in Saint-Tropez.
They made a third film together, Haunted Honeymoon, in 1986 and remained married until her death in 1989.

Details of Radner's eating disorder were reported in a book about Saturday Night Live by Doug Hill and Jeff Weingrad, which was published and received much media coverage during a period when Radner was consulting various doctors in Los Angeles about symptoms of an illness she was suffering that turned out to be cancer.
After breaking up with Jeffrey Rubinoff, Radner had an on-again-off-again relationship with Martin Short while both were appearing in Godspell.
Radner had romantic involvements with several male Saturday Night Live castmates, including Bill Murray (after a previous relationship with his brother Brian Doyle-Murray) and Dan Aykroyd. Radner's friend Judy Levy recounted Radner saying she found Ghostbusters hard to watch since the cast comprised so many of her ex-boyfriends - Aykroyd, Murray, and Harold Ramis. Radner was first married to musician G. E. Smith after they met while working on Gilda Radner – Live from New York; they divorced in 1982. 
Radner met actor Gene Wilder on the set of the Sidney Poitier film Hanky Panky (released in 1982), when the two worked together making the film. She described their first meeting as "love at first sight". After meeting Wilder, her marriage to Smith deteriorated. Radner went on to make a second film with Wilder, The Woman in Red (released in 1984), and their relationship deepened further. The two were married on September 18, 1984, in Saint-Tropez. They made a third film together, Haunted Honeymoon, in 1986 and remained married until her death in 1989.
Details of Radner's eating disorder were reported in a book about Saturday Night Live by Doug Hill and Jeff Weingrad, which was published and received much media coverage during a period when Radner was consulting various doctors in Los Angeles about symptoms of an illness she was suffering that turned out to be cancer.
Gilda Radner