She was born on 26 March 1836 at the Château de Robertsau in Strasbourg, to the former Sophie Mélanie de Coehoorn (1802–1880), and Baron Alfred Renouard de Bussière (1804–1887), who was from a wealthy Strasbourg industrial family.
He was director of the Royal Mint of Strasbourg from 1834 to 1860, before being appointed head of the Royal Mint of Paris.

Her paternal grandparents were Athanase Paul Renouard, Vicomte de Boussière and the former Friederike Wilhelmine von Franck.
Her uncle was Léon Renouard de Bussierre.
Her maternal grandparents were Louis Jacques, Baron de Coehoorn and the former Marie Margarethe Sophie von Beyer.
She was born on 26 March 1836 at the Château de Robertsau in Strasbourg, to the former Sophie Mélanie de Coehoorn (1802–1880), and Baron Alfred Renouard de Bussière (1804–1887), who was from a wealthy Strasbourg industrial family. He was director of the Royal Mint of Strasbourg from 1834 to 1860, before being appointed head of the Royal Mint of Paris.
Her paternal grandparents were Athanase Paul Renouard, Vicomte de Boussière and the former Friederike Wilhelmine von Franck. Her uncle was Léon Renouard de Bussierre. Her maternal grandparents were Louis Jacques, Baron de Coehoorn and the former Marie Margarethe Sophie von Beyer.
Mélanie de Pourtalès