Murphy began the 2008 season with the Double-A Binghamton Mets.
On August 2, a day after being promoted to the Triple-A New Orleans Zephyrs, the Mets left-handed reserve outfielder Marlon Anderson was placed on the disabled list, so Murphy was called up to the majors.
In his first major league at bat, against three-time All-Star Roy Oswalt, Murphy hit a single.
Later in the same game, he made a difficult catch against the left field wall, throwing out Hunter Pence at second base for a double play to end the inning.
As of August 9, 2008, Murphy was only the fifth Mets rookie to record 10 hits in his first 20 at bats.
Murphy hit his first home run in the bottom of the sixth inning against the Florida Marlins at Shea Stadium on August 9.
He finished the season batting .313, with two home runs and 17 runs batted in (RBIs).

Although he is a natural third baseman, Murphy began to play left field in 2008, and continued in 2009, due to the presence of David Wright on the Mets.
Murphy had a hard time transitioning to left field.
In May, Carlos Delgado underwent hip surgery and Murphy moved to first base.
Murphy led the Mets in home runs, with 12.
This tied 1977 as the season with the fewest home runs to lead a Mets team in franchise history.

On March 30, 2010, Murphy hurt his knee in a spring training game against the St. Louis Cardinals in a rundown between third base and home plate.
On June 2, while playing second base for the Buffalo Bisons, the Mets' Triple-A affiliate, he suffered a "high-grade" MCL tear while trying to turn a double play.
Although surgery was not needed, he was expected to miss 4–6 months.
Murphy suffered a season-ending injury to his MCL on August 7, 2011 after a collision with the Atlanta Braves' José Constanza.

At the time of his season-ending injury, Murphy had the 3rd highest batting average in the National League.
However, Murphy did not have enough at-bats to qualify as a league leader at the conclusion of the 2011 season.
Murphy began the 2008 season with the Double-A Binghamton Mets. On August 2, a day after being promoted to the Triple-A New Orleans Zephyrs, the Mets left-handed reserve outfielder Marlon Anderson was placed on the disabled list, so Murphy was called up to the majors. In his first major league at bat, against three-time All-Star Roy Oswalt, Murphy hit a single. Later in the same game, he made a difficult catch against the left field wall, throwing out Hunter Pence at second base for a double play to end the inning. As of August 9, 2008, Murphy was only the fifth Mets rookie to record 10 hits in his first 20 at bats. Murphy hit his first home run in the bottom of the sixth inning against the Florida Marlins at Shea Stadium on August 9. He finished the season batting .313, with two home runs and 17 runs batted in (RBIs).
Although he is a natural third baseman, Murphy began to play left field in 2008, and continued in 2009, due to the presence of David Wright on the Mets. Murphy had a hard time transitioning to left field. In May, Carlos Delgado underwent hip surgery and Murphy moved to first base. Murphy led the Mets in home runs, with 12. This tied 1977 as the season with the fewest home runs to lead a Mets team in franchise history.
On March 30, 2010, Murphy hurt his knee in a spring training game against the St. Louis Cardinals in a rundown between third base and home plate. On June 2, while playing second base for the Buffalo Bisons, the Mets' Triple-A affiliate, he suffered a "high-grade" MCL tear while trying to turn a double play. Although surgery was not needed, he was expected to miss 4–6 months. Murphy suffered a season-ending injury to his MCL on August 7, 2011 after a collision with the Atlanta Braves' José Constanza.
At the time of his season-ending injury, Murphy had the 3rd highest batting average in the National League. However, Murphy did not have enough at-bats to qualify as a league leader at the conclusion of the 2011 season.
Daniel Murphy (baseball)