Butch Alberts, former designated hitter in Major League Baseball, played for the Toronto Blue Jays
James Milton Black, composer of hymns, choir leader and Sunday school teacher.

Gary Brown, football player, running backs coach for the Dallas Cowboys
Ernest Callenbach, writer
Michael Capuzzo, journalist and author
Henry Cosgrove, Roman Catholic bishop
Allen Ertel, U.S. Congressman
Joanna Hayes, athlete, Olympic gold medalist
Daniel Hughes, abolitionist, and conductor, the Underground Railroad
James Hall Huling, U.S. Congressman
Alize Johnson, basketball player, Indiana Pacers
Lawrence Lessig, Roy L. Furman Professor of Law at Harvard Law School and the former director of the Edmond J. Safra Center for Ethics at Harvard University and candidate for the Democratic Party's nomination for President of the United States in the 2016 U.S. presidential election.

Harry J. Lincoln, early 1900s music publisher and composer
Jack Losch, football player
George Luks, Ashcan School painter
Henry J. Lutcher, businessman
Jamie McAndrew, MLB player for the Milwaukee Brewers
Tom Marino, U.S. Congressman, U.S. Attorney, District Attorney
Malcolm Muir, United States District Judge noted for the R. Budd Dwyer case
Mike Mussina,  member of the National Baseball Hall of Fame
Bob Pellegrini, American football player
H. Beam Piper, science-fiction author
Bill Reifsnyder, two-time U.S. national marathon champion
Severin Roesen (1815? –
1872), still-life painter
Sal Rosato, football player
Tina Russell, adult film actress
William Schreyer, financier
H. Paul Shuch, SETI scientist
Trisha Rae Stahl, actress
Carl Stotz, founder of Little League Baseball
Mary Szybist, poet, winner of the National Book Award for Poetry, 2013
Mike Taylor, basketball coach
Martha Dewing Woodward, female artist and art teacher in Paris, Miami, and New York
Weldon Wyckoff, baseball player
Butch Alberts, former designated hitter in Major League Baseball, played for the Toronto Blue Jays
James Milton Black, composer of hymns, choir leader and Sunday school teacher.
Gary Brown, football player, running backs coach for the Dallas Cowboys
Ernest Callenbach, writer
Michael Capuzzo, journalist and author
Henry Cosgrove, Roman Catholic bishop
Allen Ertel, U.S. Congressman
Joanna Hayes, athlete, Olympic gold medalist
Daniel Hughes, abolitionist, and conductor, the Underground Railroad
James Hall Huling, U.S. Congressman
Alize Johnson, basketball player, Indiana Pacers
Lawrence Lessig, Roy L. Furman Professor of Law at Harvard Law School and the former director of the Edmond J. Safra Center for Ethics at Harvard University and candidate for the Democratic Party's nomination for President of the United States in the 2016 U.S. presidential election.
Harry J. Lincoln, early 1900s music publisher and composer
Jack Losch, football player
George Luks, Ashcan School painter
Henry J. Lutcher, businessman
Jamie McAndrew, MLB player for the Milwaukee Brewers
Tom Marino, U.S. Congressman, U.S. Attorney, District Attorney
Malcolm Muir, United States District Judge noted for the R. Budd Dwyer case
Mike Mussina,  member of the National Baseball Hall of Fame
Bob Pellegrini, American football player
H. Beam Piper, science-fiction author
Bill Reifsnyder, two-time U.S. national marathon champion
Severin Roesen (1815? – 1872), still-life painter
Sal Rosato, football player
Tina Russell, adult film actress
William Schreyer, financier
H. Paul Shuch, SETI scientist
Trisha Rae Stahl, actress
Carl Stotz, founder of Little League Baseball
Mary Szybist, poet, winner of the National Book Award for Poetry, 2013
Mike Taylor, basketball coach
Martha Dewing Woodward, female artist and art teacher in Paris, Miami, and New York
Weldon Wyckoff, baseball player
Williamsport, Pennsylvania