The municipality of Guiuan is located at the southeasternmost tip of Samar Island.
It is bounded on the north by the municipality of Mercedes, on the east by the Philippine Sea and the Pacific Ocean, on the south by the Surigao Strait, and on the west by the Leyte Gulf.

Clustered around the municipality are numerous islands and islets such as Manicani, Calicoan, Sulangan, Candulo, Homonhon, Suluan and Tubabao.
They are protected as part of the marine reserve known as the Guiuan Protected Landscape and Seascape.

Guiuan is 109 kilometres (68 mi) south of Borongan and 154 kilometres (96 mi) from Tacloban.
It has a total land area of 175.49 square kilometres.
It is composed of sixty (60) barangays and the only town in the province with biggest number of island barangays.
The municipality of Guiuan is located at the southeasternmost tip of Samar Island. It is bounded on the north by the municipality of Mercedes, on the east by the Philippine Sea and the Pacific Ocean, on the south by the Surigao Strait, and on the west by the Leyte Gulf.
Clustered around the municipality are numerous islands and islets such as Manicani, Calicoan, Sulangan, Candulo, Homonhon, Suluan and Tubabao. They are protected as part of the marine reserve known as the Guiuan Protected Landscape and Seascape.
Guiuan is 109 kilometres (68 mi) south of Borongan and 154 kilometres (96 mi) from Tacloban. It has a total land area of 175.49 square kilometres. It is composed of sixty (60) barangays and the only town in the province with biggest number of island barangays.
Guiuan