A day after the EEC referendum, Jørgensen succeeded Jens Otto Krag as Prime Minister of Denmark.
He held this position for 14 months until the 1973 election when he was succeeded by liberal Poul Hartling.

After just over a year in opposition, he returned as prime minister with a Social Democratic minority government.
In 1978, he expanded the government by including the Liberals in a grand coalition government in order to deal with economic issues.
This coalition lasted until 23 October 1979, and for a brief period of two months in 1978 he concurrently held the position of foreign minister.
During this time, Jørgensen presided over the electoral age referendum.

For the rest of his period in office, he led again led a Social Democrat minority government.
Unable to muster support for tax increases and spending cuts, he stepped down as prime minister without calling an election on 10 September 1982, ceding the premiership to the Conservative leader Poul Schlüter.
He did, however, remain as leader of the Social Democrats until his resignation in 1987 when he was succeeded by Svend Auken.
He remained as a member of parliament until 1994.

Throughout his time in office, he showed strong leadership - guiding Denmark into the EEC and further developing Denmark’s social and welfare systems - but his policies also created a huge state budget deficit, which was compensated for by large state loans, increasing the Danish state debt substantially.
Numerous cuts were introduced to counteract this.

Nevertheless, a wide range of progressive social reforms were introduced during Jørgensen's time as prime minister.
A new Social Assistance Act introduced in 1975 simplified administration, provided new types and (in general) substantially higher benefits, together with new criteria for granting benefits.
The New Basic Education Act of June 1975 introduced 9-year general, basic education with optional 10th year and pre-school class, and also established the comprehensive principle for basic education.
The National Holiday Act of April 1979 extended the obligatory number of holidays to 30 days.
Under the law on entitlement to unemployment benefits of June 1976, the permanently self-employed became entitled to membership in unemployment funds, and consequently to unemployment benefits.
The Severance Pay Act of November 1978 introduced pre-retirement remuneration which provided unemployment benefits (for those between the ages of 58 and 66) in cases of voluntary retirement.
Under the Job Offer Scheme introduced in June 1980, unemployment benefit entitlement for long-term unemployed persons could not be lost without an offer of a new job.
A March 1975 law on regulation of housing conditions improved tenant conditions, while the Work Injury Insurance Act of March 1978 provided equality for widows and widowers.

He was President of the Nordic Council in 1986 and 1991, and was also head of the Danish delegation to the council during the same terms.

Jørgensen was elected "Dane Of The Year" in 1990.

He died on 20 March 2016, aged 93 after suffering natural causes in Copenhagen.
His funeral was held on 2 April 2016.
A day after the EEC referendum, Jørgensen succeeded Jens Otto Krag as Prime Minister of Denmark. He held this position for 14 months until the 1973 election when he was succeeded by liberal Poul Hartling.
After just over a year in opposition, he returned as prime minister with a Social Democratic minority government. In 1978, he expanded the government by including the Liberals in a grand coalition government in order to deal with economic issues. This coalition lasted until 23 October 1979, and for a brief period of two months in 1978 he concurrently held the position of foreign minister. During this time, Jørgensen presided over the electoral age referendum.
For the rest of his period in office, he led again led a Social Democrat minority government. Unable to muster support for tax increases and spending cuts, he stepped down as prime minister without calling an election on 10 September 1982, ceding the premiership to the Conservative leader Poul Schlüter. He did, however, remain as leader of the Social Democrats until his resignation in 1987 when he was succeeded by Svend Auken. He remained as a member of parliament until 1994.
Throughout his time in office, he showed strong leadership - guiding Denmark into the EEC and further developing Denmark’s social and welfare systems - but his policies also created a huge state budget deficit, which was compensated for by large state loans, increasing the Danish state debt substantially. Numerous cuts were introduced to counteract this.
Nevertheless, a wide range of progressive social reforms were introduced during Jørgensen's time as prime minister. A new Social Assistance Act introduced in 1975 simplified administration, provided new types and (in general) substantially higher benefits, together with new criteria for granting benefits. The New Basic Education Act of June 1975 introduced 9-year general, basic education with optional 10th year and pre-school class, and also established the comprehensive principle for basic education. The National Holiday Act of April 1979 extended the obligatory number of holidays to 30 days. Under the law on entitlement to unemployment benefits of June 1976, the permanently self-employed became entitled to membership in unemployment funds, and consequently to unemployment benefits. The Severance Pay Act of November 1978 introduced pre-retirement remuneration which provided unemployment benefits (for those between the ages of 58 and 66) in cases of voluntary retirement. Under the Job Offer Scheme introduced in June 1980, unemployment benefit entitlement for long-term unemployed persons could not be lost without an offer of a new job. A March 1975 law on regulation of housing conditions improved tenant conditions, while the Work Injury Insurance Act of March 1978 provided equality for widows and widowers.
He was President of the Nordic Council in 1986 and 1991, and was also head of the Danish delegation to the council during the same terms.
Jørgensen was elected "Dane Of The Year" in 1990.
He died on 20 March 2016, aged 93 after suffering natural causes in Copenhagen. His funeral was held on 2 April 2016.
Anker Jørgensen