Vasco da Gama and his wife, Catarina de Ataíde, had six sons and one daughter:
Dom Francisco da Gama, who inherited his father's titles as 2nd Count of Vidigueira and the 2nd "Admiral of the Seas of India, Arabia and Persia".
 He remained in Portugal.

Dom Estevão da Gama, after his abortive 1524 term as Indian patrol captain, he was appointed for a  three-year term as captain of Malacca, serving from 1534 to 1539 (includes the last two years of his younger brother Paulo's term).
 He was subsequently appointed as the 11th governor of India from 1540 to 1542.

Dom Paulo da Gama (having the same name as his uncle Paulo), captain of Malacca from 1533 to 1534, killed in a naval action off Malacca.

Dom Cristovão da Gama, captain of Malacca from 1538 to 1540; nominated to succeed in Malacca, but executed by Ahmad ibn Ibrahim during the Ethiopian-Adal war in 1542.

Dom Pedro da Silva da Gama, appointed captain of Malacca from 1548 to 1552.

Dom Álvaro d'Ataide da Gama appointed captain of Malacca fleet in the 1540s, captain of Malacca itself from 1552 to 1554.

Dona Isabel d'Ataide da Gama, only daughter, married Ignacio de Noronha, son of the first Count of Linhares.

His male line issue became extinct in 1747, though the title went through female line.
Vasco da Gama and his wife, Catarina de Ataíde, had six sons and one daughter:
Dom Francisco da Gama, who inherited his father's titles as 2nd Count of Vidigueira and the 2nd "Admiral of the Seas of India, Arabia and Persia".  He remained in Portugal.
Dom Estevão da Gama, after his abortive 1524 term as Indian patrol captain, he was appointed for a  three-year term as captain of Malacca, serving from 1534 to 1539 (includes the last two years of his younger brother Paulo's term).  He was subsequently appointed as the 11th governor of India from 1540 to 1542.
Dom Paulo da Gama (having the same name as his uncle Paulo), captain of Malacca from 1533 to 1534, killed in a naval action off Malacca.
Dom Cristovão da Gama, captain of Malacca from 1538 to 1540; nominated to succeed in Malacca, but executed by Ahmad ibn Ibrahim during the Ethiopian-Adal war in 1542.
Dom Pedro da Silva da Gama, appointed captain of Malacca from 1548 to 1552.
Dom Álvaro d'Ataide da Gama appointed captain of Malacca fleet in the 1540s, captain of Malacca itself from 1552 to 1554.
Dona Isabel d'Ataide da Gama, only daughter, married Ignacio de Noronha, son of the first Count of Linhares.
His male line issue became extinct in 1747, though the title went through female line.
Vasco da Gama