Luce was laid down by the Bethlehem Steel Corporation at Quincy, Massachusetts, on 1 October 1957.
The ship was launched on 11 December 1958, sponsored by the wife of Felix Stump, and commissioned on 20 May 1961 Commander David H. Bagley in command.
 USS Luce was reclassified as a guided missile destroyer on 30 June 1975 and designated DDG-38.

Luce departed Mayport, Florida, on her shakedown cruise 14 February 1962.
She spent the month of April with the U.S. 6th Fleet in her first task force operations, and returned home 11 May, where Capt.
H. J. Ereckson, Commander of Destroyer Division 84, made her his flagship.
She departed 3 August to rejoin the 6th Fleet, en route participating in NATO exercises Riptide III with units of the British and French navies.
In the next 7 months she joined in three major NATO exercises before returning home 2 March 1963.
During the spring and early summer, the guided missile destroyer conducted missile tests, trained midshipmen, and engaged in independent exercises along the Atlantic coast.

On 20 August 1963 she steamed to the Caribbean Sea for independent air, surface, and shore bombardment firings, and returned to Mayport 4 September.
She joined Task Force 23 for intensive antisubmarine warfare (ASW) and anti-aircraft (AA) exercises 28 October, and after a short operation with the aircraft carrier USS Enterprise was back in Mayport for tender availability.

On 8 February 1964 she again joined the 6th Fleet, and was called upon to stand guard for 3 weeks near the unsettled island of Cyprus to evacuate American citizens if necessary.
She hosted the Secretary of the Navy and Commander 6th Fleet 24 April for a missile firing demonstration, and then escorted the carrier USS Shangri-La on a high‑speed Atlantic crossing to Mayport, where she arrived 23 May.
In July the ship steamed to New York City to participate in operation "Sail" with a regatta of sailing craft from all over the world.
She returned to Mayport after a 4-month overhaul 28 January 1965.
The frigate had won both the Engineering and Battle Efficiency "E"s during 1964.

Luce returned to the Caribbean for intensive refresher training in March 1965.
On 29 April she embarked a company of marines at Guantanamo Bay and proceeded to the troubled Dominican Republic 30 April.
She patrolled the coast of the politically disturbed island until 8 May. She returned to the Mediterranean Sea in June for 4 months of operations with units of the Spanish, French, Greek, and Italian navies.
In September she operated with the destroyer USS Corry in the Black Sea, and she returned to the Mediterranean late in 1965.
She arrived Mayport 6 November and embarked Commander Destroyer Squadron 8.
In December she engaged in missile firing and after a brief time in port in 1966 continued testing and improving missile techniques and carrying out the fleet's widespread peacekeeping activities which guard the free world.

On 19 January 1966 an "actual nuclear incident" occurred when the nuclear warhead on a Terrier anti-air missile separated from the missile and dropped about eight feet on the Luce while the ship was docked at Mayport Naval Station.
It is recorded that "there were no personnel casualties, and aside from the dent in the warhead, no equipment was damaged."

On 13 June 1966 Luce got underway for deployment with the 6th Fleet in the Mediterranean.
After participating in various exercises with United States and other allied ships, and representing the United States at two international trade fairs, she returned to Mayport on 26 October.
The first half of 1967 saw Luce operating again in the Atlantic and Caribbean, and participating in a midshipmen training cruise in June.
On 7 August, Luce began a regular overhaul at the U.S. Naval Shipyard, Charleston, South Carolina.
She continued in overhaul until early 1968, then operated locally and in the Caribbean until departing Mayport 14 September for the Persian Gulf, sailing via Recife, Brazil, and various ports along the west and east coasts of Africa.
She arrived at Bahrain 29 October and continued to stand
Luce was laid down by the Bethlehem Steel Corporation at Quincy, Massachusetts, on 1 October 1957. The ship was launched on 11 December 1958, sponsored by the wife of Felix Stump, and commissioned on 20 May 1961 Commander David H. Bagley in command.  USS Luce was reclassified as a guided missile destroyer on 30 June 1975 and designated DDG-38.
Luce departed Mayport, Florida, on her shakedown cruise 14 February 1962. She spent the month of April with the U.S. 6th Fleet in her first task force operations, and returned home 11 May, where Capt. H. J. Ereckson, Commander of Destroyer Division 84, made her his flagship. She departed 3 August to rejoin the 6th Fleet, en route participating in NATO exercises Riptide III with units of the British and French navies. In the next 7 months she joined in three major NATO exercises before returning home 2 March 1963. During the spring and early summer, the guided missile destroyer conducted missile tests, trained midshipmen, and engaged in independent exercises along the Atlantic coast.
On 20 August 1963 she steamed to the Caribbean Sea for independent air, surface, and shore bombardment firings, and returned to Mayport 4 September. She joined Task Force 23 for intensive antisubmarine warfare (ASW) and anti-aircraft (AA) exercises 28 October, and after a short operation with the aircraft carrier USS Enterprise was back in Mayport for tender availability.
On 8 February 1964 she again joined the 6th Fleet, and was called upon to stand guard for 3 weeks near the unsettled island of Cyprus to evacuate American citizens if necessary. She hosted the Secretary of the Navy and Commander 6th Fleet 24 April for a missile firing demonstration, and then escorted the carrier USS Shangri-La on a high‑speed Atlantic crossing to Mayport, where she arrived 23 May.
In July the ship steamed to New York City to participate in operation "Sail" with a regatta of sailing craft from all over the world. She returned to Mayport after a 4-month overhaul 28 January 1965. The frigate had won both the Engineering and Battle Efficiency "E"s during 1964.
Luce returned to the Caribbean for intensive refresher training in March 1965. On 29 April she embarked a company of marines at Guantanamo Bay and proceeded to the troubled Dominican Republic 30 April. She patrolled the coast of the politically disturbed island until 8 May. She returned to the Mediterranean Sea in June for 4 months of operations with units of the Spanish, French, Greek, and Italian navies. In September she operated with the destroyer USS Corry in the Black Sea, and she returned to the Mediterranean late in 1965. She arrived Mayport 6 November and embarked Commander Destroyer Squadron 8. In December she engaged in missile firing and after a brief time in port in 1966 continued testing and improving missile techniques and carrying out the fleet's widespread peacekeeping activities which guard the free world.
On 19 January 1966 an "actual nuclear incident" occurred when the nuclear warhead on a Terrier anti-air missile separated from the missile and dropped about eight feet on the Luce while the ship was docked at Mayport Naval Station. It is recorded that "there were no personnel casualties, and aside from the dent in the warhead, no equipment was damaged."
On 13 June 1966 Luce got underway for deployment with the 6th Fleet in the Mediterranean. After participating in various exercises with United States and other allied ships, and representing the United States at two international trade fairs, she returned to Mayport on 26 October. The first half of 1967 saw Luce operating again in the Atlantic and Caribbean, and participating in a midshipmen training cruise in June. On 7 August, Luce began a regular overhaul at the U.S. Naval Shipyard, Charleston, South Carolina. She continued in overhaul until early 1968, then operated locally and in the Caribbean until departing Mayport 14 September for the Persian Gulf, sailing via Recife, Brazil, and various ports along the west and east coasts of Africa. She arrived at Bahrain 29 October and continued to stand 
USS Luce (DDG-38)