The Commodores tied for the 1921 Southern Intercollegiate Athletic Association (SIAA) football championship with an overall record of 7–0–1; Kuhn and Frank Godchaux took turns starting at quarterback.
The season opened with a 34–0 victory against the Middle Tennessee State Normal School of Murfreesboro.
The Commodore, Vanderbilt's yearbook, described the lopsided win: "Practically the only thing of note was the aerial efficiency—Kuhn to Ryan and Kuhn to McCullough".

The team defeated the Texas Longhorns 20–0 at the Texas State Fair in Dallas, although Texas was undefeated in the Southwest Conference the previous year and Vanderbilt was expected to lose by two touchdowns.
The 1921 Texas team was considered possibly the best in Longhorns history, and Vanderbilt football seemed to be declining when Georgia Tech beat it 44–0 the year before.
Dan McGugin invoked the late former Vanderbilt quarterback Irby Curry, who was killed in the war, before the game.
According to Edwin Pope's book, Football's Greatest Coaches, "The Texas game, sparked by McGugin's unforgettable oratory, was the big one; and Vandy got out of the year without a loss".
In the last scoring drive, Kuhn completed a pass to end Tot McCullough at the 8-yard (7.3 m) line to put the ball in scoring position for Godchaux after an offside penalty.

The next week Vanderbilt played the Tennessee Volunteers on a wet Old Dudley Field.
Team captain Pink Wade did not play because of low back pain, and Kuhn substituted as captain.
 Kuhn rushed for two touchdowns in a 14–0 victory.
The Tennessee coaches "never saw, in all the spying trips, such interference as the Commodores made yesterday for Doc Kuhn," remarked Blinkey Horn.
In the first quarter, Kuhn's end run of 19 yards (17 m) made the score 7–0; in the second, he had a 30 yards (27 m) touchdown run with Lynn Bomar as lead blocker.
As Horn recalled, Kuhn "made possible the touchdown by miraculous sidestepping", evading two tacklers — "miraculous because of the treacherous footing."

In the 14–0 victory over Alabama, Kuhn did not start due to injuries.
Entering the game in the fourth quarter, with the Commodores leading 7–0, Kuhn completed a 25-yard (23 m) pass to McCullough after Jess Neely's 21-yard (19 m) run.
The Commodores tied for the 1921 Southern Intercollegiate Athletic Association (SIAA) football championship with an overall record of 7–0–1; Kuhn and Frank Godchaux took turns starting at quarterback. The season opened with a 34–0 victory against the Middle Tennessee State Normal School of Murfreesboro. The Commodore, Vanderbilt's yearbook, described the lopsided win: "Practically the only thing of note was the aerial efficiency—Kuhn to Ryan and Kuhn to McCullough".
The team defeated the Texas Longhorns 20–0 at the Texas State Fair in Dallas, although Texas was undefeated in the Southwest Conference the previous year and Vanderbilt was expected to lose by two touchdowns. The 1921 Texas team was considered possibly the best in Longhorns history, and Vanderbilt football seemed to be declining when Georgia Tech beat it 44–0 the year before. Dan McGugin invoked the late former Vanderbilt quarterback Irby Curry, who was killed in the war, before the game. According to Edwin Pope's book, Football's Greatest Coaches, "The Texas game, sparked by McGugin's unforgettable oratory, was the big one; and Vandy got out of the year without a loss". In the last scoring drive, Kuhn completed a pass to end Tot McCullough at the 8-yard (7.3 m) line to put the ball in scoring position for Godchaux after an offside penalty.
The next week Vanderbilt played the Tennessee Volunteers on a wet Old Dudley Field. Team captain Pink Wade did not play because of low back pain, and Kuhn substituted as captain.  Kuhn rushed for two touchdowns in a 14–0 victory. The Tennessee coaches "never saw, in all the spying trips, such interference as the Commodores made yesterday for Doc Kuhn," remarked Blinkey Horn. In the first quarter, Kuhn's end run of 19 yards (17 m) made the score 7–0; in the second, he had a 30 yards (27 m) touchdown run with Lynn Bomar as lead blocker. As Horn recalled, Kuhn "made possible the touchdown by miraculous sidestepping", evading two tacklers — "miraculous because of the treacherous footing."
In the 14–0 victory over Alabama, Kuhn did not start due to injuries. Entering the game in the fourth quarter, with the Commodores leading 7–0, Kuhn completed a 25-yard (23 m) pass to McCullough after Jess Neely's 21-yard (19 m) run.
Oliver Kuhn