On 8 August 2013, it was announced that a deal was struck between Liverpool and Bolton subject to a medical on the same afternoon.
It was confirmed on the 9 August that Spearing had agreed a four-year deal for an undisclosed fee and he made his debut the following day in the 1–1 home draw against Reading, in which he received man-of-the-match honours.

In September 2013, Spearing was handed the captaincy at Bolton whenever incumbent Zat Knight found himself out of the starting XI, although he retained the armband when Knight returned to the team with both in the starting lineup.
On 26 July 2014, the club confirmed that Spearing would succeed Knight as captain.

On 8 August 2015, Spearing was sent off with a second booking in the opening match of the 2015–16 Championship season against Derby County.
Spearing's goal on the opening day of the 2016–17 season against Sheffield United won August's Goal of the Month award.

On 8 July 2017 the club confirmed that Spearing had left after failing to agree terms on a new contract.
On 8 August 2013, it was announced that a deal was struck between Liverpool and Bolton subject to a medical on the same afternoon. It was confirmed on the 9 August that Spearing had agreed a four-year deal for an undisclosed fee and he made his debut the following day in the 1–1 home draw against Reading, in which he received man-of-the-match honours.
In September 2013, Spearing was handed the captaincy at Bolton whenever incumbent Zat Knight found himself out of the starting XI, although he retained the armband when Knight returned to the team with both in the starting lineup. On 26 July 2014, the club confirmed that Spearing would succeed Knight as captain.
On 8 August 2015, Spearing was sent off with a second booking in the opening match of the 2015–16 Championship season against Derby County. Spearing's goal on the opening day of the 2016–17 season against Sheffield United won August's Goal of the Month award.
On 8 July 2017 the club confirmed that Spearing had left after failing to agree terms on a new contract.
Jay Spearing