Naldi was asked to perform in a short film with Johnny Dooley, a Scottish comedian who, despite his last name, was unrelated to her.
She soon quit the film, however, after realizing that Dooley had romantic intentions with another woman.
Naldi was then offered a role in A Divorce of Convenience with Owen Moore.
Following those two films, she had small roles in several independent films before being cast as the exotic character Gina in Paramount Pictures's 1920 release Dr. Jekyll and Mr. Hyde starring John Barrymore.
Barrymore himself reportedly recommended her for the role after he “spotted” her dancing at the Winter Garden.
Her noted performance in that film subsequently afforded Naldi more career opportunities.
It also established her long-term friendship with Barrymore, who affectionately nicknamed her his “Dumb Duse”.

Naldi was selected by Spanish author Vicente Blasco Ibáñez for the role of Doña Sol in film version of his novel, Blood and Sand (1922).
Naldi was signed by Famous Players-Lasky for the role, and it became her first pairing with screen idol Rudolph Valentino; the film was a major success, for it gave Naldi the image of a vamp, which would follow her for the rest of her life.
Naldi and Valentino were never romantic, and she would be one of the few to befriend his wife Natacha Rambova though that friendship would sour when the Valentinos divorced.

Naldi during this time posed for famous Peruvian artist Alberto Vargas, who painted her embracing a bust of a satyr.
In Vargas's original “pin-up” painting, Naldi is depicted topless, although copies of the portrait that were published and widely distributed in the 1920s, such as in the art and entertainment magazine Shadowland, were “modified” by the addition of clothing to cover her partially visible left breast.

While Valentino went on his one-man strike, which prevented him from appearing on film, Naldi took on several Famous Players-Lasky roles with growing importance including The Ten Commandments (1923), directed by Cecil B. DeMille.
 When Valentino returned and fixed his contract woes, she joined him for his final Famous Players-Lasky film, the now lost A Sainted Devil (1924).
 Naldi left the company soon after.

In 1924 the Valentinos and Naldi traveled to France in order to do research for the film The Hooded Falcon which was never made.
Upon  returning to California, the duo made Cobra.
 The film was not well received, and Cobra became the last film in which Naldi and Valentino starred together.
The Valentinos' marriage was ending around this time.
After Valentino signed a contract with United Artists, he banned Rambova from the set.
 She was given her own film as a consolation.
 Naldi starred in Rambova's 1925 production What Price Beauty?
The film suffered distribution problems, was barely noted at the time, but is noteworthy for being actress Myrna Loy's first screen appearance.

After finishing the Dorothy Gish film Clothes Make the Pirate, Naldi left for France for a short vacation, where she married J. Searle Barclay during this time.
 Despite multiple rumors that she had retired, Naldi began work on several films, including Alfred Hitchcock's second directorial effort, 1926's The Mountain Eagle.
She is often mistakenly credited for appearing in Hitchcock's The Pleasure Garden.

Naldi made two films in France and one in Italy before retiring.
Despite having an acceptable voice, Naldi never made a “talkie”.
Naldi was asked to perform in a short film with Johnny Dooley, a Scottish comedian who, despite his last name, was unrelated to her. She soon quit the film, however, after realizing that Dooley had romantic intentions with another woman. Naldi was then offered a role in A Divorce of Convenience with Owen Moore. Following those two films, she had small roles in several independent films before being cast as the exotic character Gina in Paramount Pictures's 1920 release Dr. Jekyll and Mr. Hyde starring John Barrymore. Barrymore himself reportedly recommended her for the role after he “spotted” her dancing at the Winter Garden. Her noted performance in that film subsequently afforded Naldi more career opportunities. It also established her long-term friendship with Barrymore, who affectionately nicknamed her his “Dumb Duse”.
Naldi was selected by Spanish author Vicente Blasco Ibáñez for the role of Doña Sol in film version of his novel, Blood and Sand (1922). Naldi was signed by Famous Players-Lasky for the role, and it became her first pairing with screen idol Rudolph Valentino; the film was a major success, for it gave Naldi the image of a vamp, which would follow her for the rest of her life. Naldi and Valentino were never romantic, and she would be one of the few to befriend his wife Natacha Rambova though that friendship would sour when the Valentinos divorced.
Naldi during this time posed for famous Peruvian artist Alberto Vargas, who painted her embracing a bust of a satyr. In Vargas's original “pin-up” painting, Naldi is depicted topless, although copies of the portrait that were published and widely distributed in the 1920s, such as in the art and entertainment magazine Shadowland, were “modified” by the addition of clothing to cover her partially visible left breast.
While Valentino went on his one-man strike, which prevented him from appearing on film, Naldi took on several Famous Players-Lasky roles with growing importance including The Ten Commandments (1923), directed by Cecil B. DeMille.  When Valentino returned and fixed his contract woes, she joined him for his final Famous Players-Lasky film, the now lost A Sainted Devil (1924).  Naldi left the company soon after.
In 1924 the Valentinos and Naldi traveled to France in order to do research for the film The Hooded Falcon which was never made. Upon  returning to California, the duo made Cobra.  The film was not well received, and Cobra became the last film in which Naldi and Valentino starred together. The Valentinos' marriage was ending around this time. After Valentino signed a contract with United Artists, he banned Rambova from the set.  She was given her own film as a consolation.  Naldi starred in Rambova's 1925 production What Price Beauty? The film suffered distribution problems, was barely noted at the time, but is noteworthy for being actress Myrna Loy's first screen appearance.
After finishing the Dorothy Gish film Clothes Make the Pirate, Naldi left for France for a short vacation, where she married J. Searle Barclay during this time.  Despite multiple rumors that she had retired, Naldi began work on several films, including Alfred Hitchcock's second directorial effort, 1926's The Mountain Eagle. She is often mistakenly credited for appearing in Hitchcock's The Pleasure Garden.
Naldi made two films in France and one in Italy before retiring. Despite having an acceptable voice, Naldi never made a “talkie”.
Nita Naldi