The river begins as Sesekinika Lake in geographic Maisonville Township and flow west under Ontario Highway 11, turns south, heads through Kenogami Lake, then back under Ontario Highway 11 at the settlement of Kenogami Lake, flows under the Ontario Northland Railway (ONR) mainline and past Kenogami Lake Station, enters the municipality of Kirkland Lake and reaches the community of Swastika.
It passes under Ontario Highway 66 and back under the ONR mainline, past the community of Tarzwell on Round Lake, under Ontario Highway 112, into the township of Chamberlain, once again under the ONR mainline, over the Eighty Foot Falls and Stuart's Rapids, takes in the left tributary Misema River and takes in the right tributary of Englehart River in geographic Marter Township, just north of the town of Englehart.
The river heads under Ontario Highway 624, takes in the left tributary Larder River, passes into the municipality of Evanturel and then the geographic Ingram Township, flows under Ontario Highway 569 at the community of Tomstown and reaches the township of Hilliard where it passes once again under Ontario Highway 569.
It heads briefly through the township of Brethour, then into the township of Casey, flows under Ontario Highway 65 at the community of Judge, and reaches its mouth at Baie Paulson (Paulson Bay) at the north end of Lake Timiskaming on the Ottawa River, east of the settlement of Sutton Bay in the township of Harris and just west of the border with the province of Quebec.
The Ottawa River flows to the Saint Lawrence River at Montreal.
The river begins as Sesekinika Lake in geographic Maisonville Township and flow west under Ontario Highway 11, turns south, heads through Kenogami Lake, then back under Ontario Highway 11 at the settlement of Kenogami Lake, flows under the Ontario Northland Railway (ONR) mainline and past Kenogami Lake Station, enters the municipality of Kirkland Lake and reaches the community of Swastika. It passes under Ontario Highway 66 and back under the ONR mainline, past the community of Tarzwell on Round Lake, under Ontario Highway 112, into the township of Chamberlain, once again under the ONR mainline, over the Eighty Foot Falls and Stuart's Rapids, takes in the left tributary Misema River and takes in the right tributary of Englehart River in geographic Marter Township, just north of the town of Englehart. The river heads under Ontario Highway 624, takes in the left tributary Larder River, passes into the municipality of Evanturel and then the geographic Ingram Township, flows under Ontario Highway 569 at the community of Tomstown and reaches the township of Hilliard where it passes once again under Ontario Highway 569. It heads briefly through the township of Brethour, then into the township of Casey, flows under Ontario Highway 65 at the community of Judge, and reaches its mouth at Baie Paulson (Paulson Bay) at the north end of Lake Timiskaming on the Ottawa River, east of the settlement of Sutton Bay in the township of Harris and just west of the border with the province of Quebec. The Ottawa River flows to the Saint Lawrence River at Montreal.
Blanche River (Lake Timiskaming)