Quinn's first wife was the adopted daughter of Cecil B. DeMille, actress Katherine DeMille; they wed in 1937.
The couple had five children: Christopher (1938–1941), Christina (born December 1, 1941), Catalina (born November 21, 1942), Duncan (born August 4, 1945), and Valentina (born December 26, 1952).
Their first child, Christopher, aged two, drowned in the lily pond of next-door neighbor W. C. Fields.

In 1965, Quinn and DeMille divorced because of his affair with Italian costume designer Jolanda Addolori, whom he married in 1966.
They had three children: Francesco Quinn (March 22, 1963 – August 5, 2011), Danny Quinn (born April 16, 1964), and Lorenzo Quinn (born May 7, 1966).

In the 1970s, during his marriage to Addolori, Quinn also had two children with an event producer in Los Angeles named Friedel Dunbar: Sean Quinn (born February 7, 1973) and Alexander Anthony Quinn (born December 30, 1976).

By the 1990s, Quinn then had two children with his secretary, Katherine Benvin; daughter Antonia Patricia Rose Quinn (born July 23, 1993) and son Ryan Nicholas Quinn (born July 5, 1996).
His marriage with Addolori finally ended in divorce in August 1997.
He then married Benvin in December 1997 and remained married until his death, in June 2001.
Quinn's first wife was the adopted daughter of Cecil B. DeMille, actress Katherine DeMille; they wed in 1937. The couple had five children: Christopher (1938–1941), Christina (born December 1, 1941), Catalina (born November 21, 1942), Duncan (born August 4, 1945), and Valentina (born December 26, 1952). Their first child, Christopher, aged two, drowned in the lily pond of next-door neighbor W. C. Fields.
In 1965, Quinn and DeMille divorced because of his affair with Italian costume designer Jolanda Addolori, whom he married in 1966. They had three children: Francesco Quinn (March 22, 1963 – August 5, 2011), Danny Quinn (born April 16, 1964), and Lorenzo Quinn (born May 7, 1966).
In the 1970s, during his marriage to Addolori, Quinn also had two children with an event producer in Los Angeles named Friedel Dunbar: Sean Quinn (born February 7, 1973) and Alexander Anthony Quinn (born December 30, 1976).
By the 1990s, Quinn then had two children with his secretary, Katherine Benvin; daughter Antonia Patricia Rose Quinn (born July 23, 1993) and son Ryan Nicholas Quinn (born July 5, 1996). His marriage with Addolori finally ended in divorce in August 1997. He then married Benvin in December 1997 and remained married until his death, in June 2001.
Anthony Quinn