Yasushi Akimoto was offered the chance to start a production in Nagoya along with the renewal of the Sunshine Sakae 2F, when he was thinking of expanding his "48 project" nationwide.
He had offers from outside Japan, but he decided to use Nagoya as the place to move on with the project.
Akimoto said that selected members from AKB48 and SKE48 may release a single together.
They released their first single in 2009.

In AKB48's single "Ōgoe Diamond", Jurina Matsui became the center and the first and only member of SKE48 to be featured on a single cover and in the song itself.
Including Matsui, some members of SKE48 have appeared in the PV, marking the first collaboration made by the two groups so far.

On May 28, 2011, Avex picked up SKE48 and were to release their debut single under the label called “Pareo wa Emerald” on July 27, 2011.

On August 25, it was announced that SKE48 member Yui Matsushita would leave the group at the end of September 2011 due to ankle injuries.

On August 7, 2012, SKE48 member and captain of Team S, Hirata Rikako announced her graduation to pursue a career as a reporter.

On the first day of the Tokyo Dome Concert held on August 24, 2012, it was announced that Rie Kitahara of AKB48, Team K would hold a concurrent position in SKE48.
Anna Ishida of Team KII would hold a concurrent position in AKB48, Team B.
On November 1, it was announced that Kumi Yagami, one of the group's first generation members, would graduate but the date was not announced.

On December 9, SKE48CAFE&SHOP with AKB48 was opened to the building 5F with a theater.
There is a cooking menu that the members of SKE48 devised.

On January 15, 2013, it was announced that eight members, three from Team S, two each from Team KII and E, and one kenkyusei, would graduate from the group, along with Yagami (whose graduation was already announced in November 2012) sometime in the spring 2013.
On April 13, it was announced that teams were to be reorganized and nine kenkyusei members would be promoted to full members.
Yuka Nakanishi became the captain of SKE48 as well as leader of Team S, and Rena Matsui was promoted to leader of Team E. Rie Kitahara, who was in both SKE48 and AKB48, was removed from SKE48's lineup during the final concert of "AKB48 Group Rinji Soukai" concert series at the Nippon Budokan on 28 April, with her final theater performance as a SKE48 member on May 9.

On February 24, 2014 it was announced that Rena Matsui would hold a concurrent position with Nogizaka46 after teams were reorganized and kenkyusei members were promoted to full members.
Concurrent member with SKE48 and AKB48 Mina Ōba was fully transferred to SKE48 Team KII and other members from AKB48, NMB48, and HKT48 were permanently transferred or given concurrent positions in SKE48.
Former Team K member Miyazawa Sae was transferred from SNH48 and appointed the new leader of Team S.
On March 15, 2015, the members who passed the seventh generation audition were revealed.
On June 6, 2015, SKE48 became the first sister group to have more members rank in the annual Single Senbatsu Sousenkyo than AKB48.
In 2015, SKE48 released two singles.
A third release was published under the label "Love Crescendo" and was promoted as SKE48's first sub project.

On February 7, 2020, Jurina Matsui announced her graduation from SKE48.
In July 2020, Kazuya Ebine, an executive from SKE48's managing company Zest, was arrested for allegedly paying two underage girls to have sex in his car in November 2019.
Yasushi Akimoto was offered the chance to start a production in Nagoya along with the renewal of the Sunshine Sakae 2F, when he was thinking of expanding his "48 project" nationwide. He had offers from outside Japan, but he decided to use Nagoya as the place to move on with the project. Akimoto said that selected members from AKB48 and SKE48 may release a single together. They released their first single in 2009.
In AKB48's single "Ōgoe Diamond", Jurina Matsui became the center and the first and only member of SKE48 to be featured on a single cover and in the song itself. Including Matsui, some members of SKE48 have appeared in the PV, marking the first collaboration made by the two groups so far.
On May 28, 2011, Avex picked up SKE48 and were to release their debut single under the label called “Pareo wa Emerald” on July 27, 2011.
On August 25, it was announced that SKE48 member Yui Matsushita would leave the group at the end of September 2011 due to ankle injuries.
On August 7, 2012, SKE48 member and captain of Team S, Hirata Rikako announced her graduation to pursue a career as a reporter.
On the first day of the Tokyo Dome Concert held on August 24, 2012, it was announced that Rie Kitahara of AKB48, Team K would hold a concurrent position in SKE48. Anna Ishida of Team KII would hold a concurrent position in AKB48, Team B.
On November 1, it was announced that Kumi Yagami, one of the group's first generation members, would graduate but the date was not announced.
On December 9, SKE48CAFE&SHOP with AKB48 was opened to the building 5F with a theater. There is a cooking menu that the members of SKE48 devised.
On January 15, 2013, it was announced that eight members, three from Team S, two each from Team KII and E, and one kenkyusei, would graduate from the group, along with Yagami (whose graduation was already announced in November 2012) sometime in the spring 2013. On April 13, it was announced that teams were to be reorganized and nine kenkyusei members would be promoted to full members. Yuka Nakanishi became the captain of SKE48 as well as leader of Team S, and Rena Matsui was promoted to leader of Team E. Rie Kitahara, who was in both SKE48 and AKB48, was removed from SKE48's lineup during the final concert of "AKB48 Group Rinji Soukai" concert series at the Nippon Budokan on 28 April, with her final theater performance as a SKE48 member on May 9.
On February 24, 2014 it was announced that Rena Matsui would hold a concurrent position with Nogizaka46 after teams were reorganized and kenkyusei members were promoted to full members. Concurrent member with SKE48 and AKB48 Mina Ōba was fully transferred to SKE48 Team KII and other members from AKB48, NMB48, and HKT48 were permanently transferred or given concurrent positions in SKE48. Former Team K member Miyazawa Sae was transferred from SNH48 and appointed the new leader of Team S.
On March 15, 2015, the members who passed the seventh generation audition were revealed. On June 6, 2015, SKE48 became the first sister group to have more members rank in the annual Single Senbatsu Sousenkyo than AKB48. In 2015, SKE48 released two singles. A third release was published under the label "Love Crescendo" and was promoted as SKE48's first sub project.
On February 7, 2020, Jurina Matsui announced her graduation from SKE48. In July 2020, Kazuya Ebine, an executive from SKE48's managing company Zest, was arrested for allegedly paying two underage girls to have sex in his car in November 2019.
SKE48