Cathy Munsch (Jamie Lee Curtis) is the seductive and manipulative dean of Wallace University, who hates Kappa Kappa Tau and Chanel Oberlin causing her to threaten to revoke its charter.
She covered the bathtub baby incident at Kappa House in 1995 by driving Bethany, Mandy and Coco in the middle of nowhere and burying Sophia Doyle's body before telling the girls to leave school immediately.
It is revealed that she knew the bathtub babies's identity which she confessed to Hester (who was the female baby and the Red Devil) and threatens to turn her into the police.

She despises Gigi Caldwell who has a relationship with Wes but after Gigi's death, Cathy falls in love with Wes.
She also hates Feather McCarthy, a former student who had an affair with Cathy's husband causing Cathy to go insane and kicked her husband out the house and often dressed up in Feather's clothes and terrorised her, managing to kick Feather out of Kappa House.
Cathy later killed and dismembered her ex-husband but put the blame on Feather who was sent to an asylum for life.

In 2016, Cathy confronts Hester about her being the killer and threatens to turn her into the police while Hester also threatens to turn Cathy into the police for the cover up of Sophia Doyle back in 1995 and the murder of her ex-husband.
They both part ways and she continues to live a happy life with the horrors of last fall behind Wallace University and Hester herself.

In the second season, Cathy has left the University and has started the C.U.R.E. Institute Hospital.
She recruits Zayday, Chanel, Chanel #5, and Chanel #3 to work for her.
Not long after that, the patients at the C.U.R.E. Institute Hospital are killed by the Green Meanie.
The real reason she opened the hospital was because she claims to have suffering from a disease, which Zayday diagnoses as Kuru, which is caused by cannibalism.
Her publicist had mistakenly booked her flight to Papua New Guinea and a stranger invited her to a funeral and ate a deceased man's brain, without realizing it.
Zayday indicates that she has about a year to live, and decides to keep it a secret.
Cathy's illness becomes more serious and she will die within a month.
Dr. Brock asks for her hand in marriage in order for him and Hester to steal her money.
However, Chanel #5 checks her tests and does not believe she has Kuru.
They perform a surgery to test if she has Kuru, which concludes that she does not.
All of her symptoms were caused by extreme dehydration resulting from never drinking water, only scotch.
She finds out that the brain she had eaten in Papua New Guinea was lamb, not human.
After the deaths of Jane Hollis, Cassidy and Nurse Hoffel, Cathy's money gets stolen by Hester and Dr. Brock, but she ends up selling the hospital for a huge profit and becomes a sex therapist for women over 50.
Cathy Munsch (Jamie Lee Curtis) is the seductive and manipulative dean of Wallace University, who hates Kappa Kappa Tau and Chanel Oberlin causing her to threaten to revoke its charter. She covered the bathtub baby incident at Kappa House in 1995 by driving Bethany, Mandy and Coco in the middle of nowhere and burying Sophia Doyle's body before telling the girls to leave school immediately. It is revealed that she knew the bathtub babies's identity which she confessed to Hester (who was the female baby and the Red Devil) and threatens to turn her into the police.
She despises Gigi Caldwell who has a relationship with Wes but after Gigi's death, Cathy falls in love with Wes. She also hates Feather McCarthy, a former student who had an affair with Cathy's husband causing Cathy to go insane and kicked her husband out the house and often dressed up in Feather's clothes and terrorised her, managing to kick Feather out of Kappa House. Cathy later killed and dismembered her ex-husband but put the blame on Feather who was sent to an asylum for life.
In 2016, Cathy confronts Hester about her being the killer and threatens to turn her into the police while Hester also threatens to turn Cathy into the police for the cover up of Sophia Doyle back in 1995 and the murder of her ex-husband. They both part ways and she continues to live a happy life with the horrors of last fall behind Wallace University and Hester herself.
In the second season, Cathy has left the University and has started the C.U.R.E. Institute Hospital. She recruits Zayday, Chanel, Chanel #5, and Chanel #3 to work for her. Not long after that, the patients at the C.U.R.E. Institute Hospital are killed by the Green Meanie. The real reason she opened the hospital was because she claims to have suffering from a disease, which Zayday diagnoses as Kuru, which is caused by cannibalism. Her publicist had mistakenly booked her flight to Papua New Guinea and a stranger invited her to a funeral and ate a deceased man's brain, without realizing it. Zayday indicates that she has about a year to live, and decides to keep it a secret. Cathy's illness becomes more serious and she will die within a month. Dr. Brock asks for her hand in marriage in order for him and Hester to steal her money. However, Chanel #5 checks her tests and does not believe she has Kuru. They perform a surgery to test if she has Kuru, which concludes that she does not. All of her symptoms were caused by extreme dehydration resulting from never drinking water, only scotch. She finds out that the brain she had eaten in Papua New Guinea was lamb, not human. After the deaths of Jane Hollis, Cassidy and Nurse Hoffel, Cathy's money gets stolen by Hester and Dr. Brock, but she ends up selling the hospital for a huge profit and becomes a sex therapist for women over 50.
List of Scream Queens characters