By air
Guiuan Airport has a 2,800-metre (9,200-ft) runway which can service light private planes, chartered cargo and military planes.
The Guiuan Airport was upgraded in 2010.
Cebu-based airline Mid-Sea Express had scheduled flights from Cebu City to Guiuan twice weekly on Saturdays and Mondays, using a 19-seater Jetstream 32 aircraft.
Service started in 2012 but has now been discontinued.

By land
The town is accessible by land with highway connection from Tacloban City, about three-four hours travel.
Several buses and vans regularly shuttle passengers to Guiuan.
It is also accessible from Borongan City.
Alternatively, several bus companies have daily trips to Guiuan from Manila.
Travel time is approximately twenty-one hours.

Since the town is a coastal municipality, it has a small seaport operational throughout the year.
By air
Guiuan Airport has a 2,800-metre (9,200-ft) runway which can service light private planes, chartered cargo and military planes. The Guiuan Airport was upgraded in 2010. Cebu-based airline Mid-Sea Express had scheduled flights from Cebu City to Guiuan twice weekly on Saturdays and Mondays, using a 19-seater Jetstream 32 aircraft. Service started in 2012 but has now been discontinued.
By land
The town is accessible by land with highway connection from Tacloban City, about three-four hours travel. Several buses and vans regularly shuttle passengers to Guiuan. It is also accessible from Borongan City. Alternatively, several bus companies have daily trips to Guiuan from Manila. Travel time is approximately twenty-one hours.
Since the town is a coastal municipality, it has a small seaport operational throughout the year.
Guiuan