Henry hired Swiss troops to help him defend himself in Paris.
The Parisians, however, claimed the right to defend the city themselves.
On 12 May 1588, they set up barricades in the streets and refused to take orders from anyone except the Duke of Guise.
When Catherine tried to go to Mass, she found her way barred, though she was allowed through the barricades.
The chronicler L'Estoile reported that she cried all through her lunch that day.
She wrote to Bellièvre, "Never have I seen myself in such trouble or with so little light by which to escape."
As usual, Catherine advised the king, who had fled the city in the nick of time, to compromise and live to fight another day.
On 15 June 1588, Henry duly signed the Act of Union, which gave in to all the League's latest demands.

On 8 September 1588 at Blois, where the court had assembled for a meeting of the Estates, Henry dismissed all his ministers without warning.
Catherine, in bed with a lung infection, had been kept in the dark.
The king's actions effectively ended her days of power.

At the meeting of the Estates, Henry thanked Catherine for all she had done.
He called her not only the mother of the king but the mother of the state.
Henry did not tell Catherine of his plan for a solution to his problems.(And yet the Mistress of the Duke of Guise who persuaded him to call on the King was of Catherine's entourage/clique  making it highly unlikely Catherine was 'in the dark')  On 22 December 1588, Guise spent the night with his current mistress Charlotte de Sauve, the most accomplished and notorious member of Catherine de' Medici's group of female spies known as the "Flying Squadron"   On 23 December 1588, he asked the Duke of Guise to call on him at the Château de Blois.
As Guise entered the king's chamber, the Forty-five plunged their blades into his body, and he died at the foot of the king's bed.
At the same moment, eight members of the Guise family were rounded up, including the Duke of Guise's brother, Louis II, Cardinal of Guise, whom Henry's men hacked to death the next day in the palace dungeons.
Immediately after the murder of Guise, Henry entered Catherine's bedroom on the floor below and announced, "Please forgive me.
Monsieur de Guise is dead.
He will not be spoken of again.
I have had him killed.
I have done to him what he was going to do to me."
Catherine's immediate reaction is not known; but on Christmas Day, she told a friar, "Oh, wretched man!
What has he done?
 ... Pray for him ... I see him rushing towards his ruin."
She visited her old friend Cardinal de Bourbon on 1 January 1589 to tell him she was sure he would soon be freed.
He shouted at her, "Your words, Madam, have led us all to this butchery."
She left in tears.

On 5 January 1589, Catherine died at the age of sixty-nine, probably from pleurisy.
L'Estoile wrote: "those close to her believed that her life had been shortened by displeasure over her son's deed."
He added that she had no sooner died than she was treated with as much consideration as a dead goat.
Because Paris was held by enemies of the crown, Catherine had to be buried provisionally at Blois.
Eight months later, Jacques Clément stabbed Henry III to death.
At the time, Henry was besieging Paris with the King of Navarre, who would succeed him as Henry IV of France.
Henry III's assassination ended nearly three centuries of Valois rule and brought the Bourbon dynasty into power.
Years later, Diane, daughter of Henry II and Philippa Duci, had Catherine's remains reinterred in the Saint-Denis basilica in Paris.
In 1793, a revolutionary mob tossed her bones into a mass grave with those of the other kings and queens.

Henry IV was later reported to have said of Catherine:
I ask you, what could a woman do, left by the death of her husband with five little children on her arms, and two families of France who were thinking of grasping the crown—our own [the Bourbons] and the Guises?
Was she not compelled to play strange parts to deceive first one and then the other, in order to guard, as she did, her sons, who successively reigned through the wise
Henry hired Swiss troops to help him defend himself in Paris. The Parisians, however, claimed the right to defend the city themselves. On 12 May 1588, they set up barricades in the streets and refused to take orders from anyone except the Duke of Guise. When Catherine tried to go to Mass, she found her way barred, though she was allowed through the barricades. The chronicler L'Estoile reported that she cried all through her lunch that day. She wrote to Bellièvre, "Never have I seen myself in such trouble or with so little light by which to escape." As usual, Catherine advised the king, who had fled the city in the nick of time, to compromise and live to fight another day. On 15 June 1588, Henry duly signed the Act of Union, which gave in to all the League's latest demands.
On 8 September 1588 at Blois, where the court had assembled for a meeting of the Estates, Henry dismissed all his ministers without warning. Catherine, in bed with a lung infection, had been kept in the dark. The king's actions effectively ended her days of power.
At the meeting of the Estates, Henry thanked Catherine for all she had done. He called her not only the mother of the king but the mother of the state. Henry did not tell Catherine of his plan for a solution to his problems.(And yet the Mistress of the Duke of Guise who persuaded him to call on the King was of Catherine's entourage/clique  making it highly unlikely Catherine was 'in the dark')  On 22 December 1588, Guise spent the night with his current mistress Charlotte de Sauve, the most accomplished and notorious member of Catherine de' Medici's group of female spies known as the "Flying Squadron"   On 23 December 1588, he asked the Duke of Guise to call on him at the Château de Blois. As Guise entered the king's chamber, the Forty-five plunged their blades into his body, and he died at the foot of the king's bed. At the same moment, eight members of the Guise family were rounded up, including the Duke of Guise's brother, Louis II, Cardinal of Guise, whom Henry's men hacked to death the next day in the palace dungeons. Immediately after the murder of Guise, Henry entered Catherine's bedroom on the floor below and announced, "Please forgive me. Monsieur de Guise is dead. He will not be spoken of again. I have had him killed. I have done to him what he was going to do to me." Catherine's immediate reaction is not known; but on Christmas Day, she told a friar, "Oh, wretched man! What has he done? ... Pray for him ... I see him rushing towards his ruin." She visited her old friend Cardinal de Bourbon on 1 January 1589 to tell him she was sure he would soon be freed. He shouted at her, "Your words, Madam, have led us all to this butchery." She left in tears.
On 5 January 1589, Catherine died at the age of sixty-nine, probably from pleurisy. L'Estoile wrote: "those close to her believed that her life had been shortened by displeasure over her son's deed." He added that she had no sooner died than she was treated with as much consideration as a dead goat. Because Paris was held by enemies of the crown, Catherine had to be buried provisionally at Blois. Eight months later, Jacques Clément stabbed Henry III to death. At the time, Henry was besieging Paris with the King of Navarre, who would succeed him as Henry IV of France. Henry III's assassination ended nearly three centuries of Valois rule and brought the Bourbon dynasty into power. Years later, Diane, daughter of Henry II and Philippa Duci, had Catherine's remains reinterred in the Saint-Denis basilica in Paris. In 1793, a revolutionary mob tossed her bones into a mass grave with those of the other kings and queens.
Henry IV was later reported to have said of Catherine:
I ask you, what could a woman do, left by the death of her husband with five little children on her arms, and two families of France who were thinking of grasping the crown—our own [the Bourbons] and the Guises? Was she not compelled to play strange parts to deceive first one and then the other, in order to guard, as she did, her sons, who successively reigned through the wise
Catherine de' Medici