what is the function of ethanol in transamination reaction
Transamination
Ping Pong Bi Bi mechanism of PLP dependent enzyme catalyzed transamination . Aminotransferase reaction occurs in two stages consisting of three steps : Transimination , Tautomerisation and Hydolysis . In the first stage , alpha amino group of the aminoacid is transferred to PLP yielding an alpha ketoacid and PMP . In the second stage of the reaction , in which the amino group of PMP is transferred to a different alpha Ketoacid to yield a new alpha amino acid and PLP . The product of transamination reactions depend on the availability of α - keto acids . The products usually are either alanine , aspartate or glutamate , since their corresponding alpha - keto acids are produced through metabolism of fuels . Being a major degradative aminoacid pathway , lysine , proline and threonine are the only three amino acids that do not always undergo transamination and rather use respective dehydrogenase .
Ping Pong Bi Bi mechanism of PLP dependent enzyme catalyzed transamination . Aminotransferase reaction occurs in two stages consisting of three steps : Transimination , Tautomerisation and Hydolysis . In the first stage , alpha amino group of the aminoacid is transferred to PLP yielding an alpha ketoacid and PMP . In the second stage of the reaction , in which the amino group of PMP is transferred to a different alpha Ketoacid to yield a new alpha amino acid and PLP . The product of transamination reactions depend on the availability of α - keto acids . The products usually are either alanine , aspartate or glutamate , since their corresponding alpha - keto acids are produced through metabolism of fuels . Being a major degradative aminoacid pathway , lysine , proline and threonine are the only three amino acids that do not always undergo transamination and rather use respective dehydrogenase .