Not counting the super-transmitters, it has been estimated that each case could generate approximately two secondary cases with an incubation period of between 4 and 7 days, with the peak of the viral load appearing on the 10th day of illness.
Mikurupuko ya ugojwa wa sindromu mbaya kali ya kupumua (SARS) na sindromu ya kupumua ya Mashariki ya Kati (MERS) imebadilisha mambo na kudhihirisha jinsi maambukizi ya HCoV yanaweza kuwa hatari na kutishia maisha.