The extracellular domain of ACE2 is cleaved from the transmembrane domain by another enzyme called sheddase; the resulting soluble protein is released into the bloodstream and finally excreted in the urine.
Kikoa cha giligili iliyo nje cha ACE2 kimeshikilia kikoa cha utando kwa kimeng&apos;enya kingine kinachojulikana kama sheddase, na protini inayotokea inayoyeyuka hutolewa kwenye mfumo wa damu na mwishowe kutolewa kupitia mkojo.