Specifically, binding of the SARS-CoV and SARS-CoV2 spike protein S1 to the cell surface ACE2 enzymatic domain results in endocytosis and translocation of both the virus and the enzyme in the endosomes located inside the cells.
Kihususa, ushikamano wa protini ya SI ya SARS-CoV na SARS-CoV2 kwa kikoa cha mmeng&apos;enyo cha ACE2 kwenye sehemu ya juu ya seli husababisha endocytosis na uhamishaji wa virusi na kimeng&apos;enya kwa endosomu zilizo ndani ya seli.