However, during this century, we have known two highly pathogenic coronaviruses for humans, namely SARS-CoV and MERS-CoV, which caused an epidemic which started in China in 2003 and in Saudi Arabia in 2012, respectively, before rapidly spreading to many other countries with high morbidity and mortality.
Hata hivyo, katika karne hii, tumekumbana na CoV vya binadamu vinavyosambazwa zaidi na virusi mara mbili, yaani, SARS-CoV na MERS-CoV, ambavyo vilisababisha mkurupuko nchini China mwaka 2003 na Saudi Arabia mwaka 2012, mtawalia, na punde vikaenea haraka katika mataifa mengine mengi vikiwa na hali ya juu ya kuwa ugonjwa na viwango vya vifo.