Spike (S) envelope glycoprotein binds to angiotensin-converting enzyme 2 (ACE2) and dipeptidyl peptidase-4 (DPP4) of its cell receptors for SARS-CoV and MERS-CoV , respectively, then membrane fusion occurs.
Mfungamano wa glycoprotini (S) unafunga vitambuzi vya seli zake vya angiotensini vinavyobadilisha enzaimu 2 (ACE2) na dipeptdyl peptidase 4 (DPP4) ya SARS-CoV na MERS-CoV, mtawalia kisha muunganisho wa utando kutokea.