They must maintain and spread in their zoonotic reservoirs and seek an opportunity to reach potential human targets, probably via one or more intermediate hosts and enhancers.
Hususan, tunaangazia na kujadili mada ya kawaida kwamba virusi vizalishaji vya HCoV kawaida havina uwezo wa kusababisha magonjwa ndani ya wabebaji wake asilia lakini huwa na uwezo wa kusababisha ugonjwa baada ya kusambazwa baina ya aina ya wanyama hadi kwa mbebaji mpya.