In contrast, in asymptomatic carriers, the immune response was uncoupled from CoV replication.
Kinyume chake, ikiwa virusi vya HCoV vimeingia kwa mara ya kwanza ndani ya mbebaji wa kati kabla au karibu kuingia kwake kwa binadamu, huwa havijazoeleka vyema katika mazingira hayo mapya na mara nyingi husababisha ugonjwa.