Compared to other single-stranded RNA viruses, the estimated mutation rates of CoVs could be considered “moderate” to “high” with an average substitution rate of ~10-4 substitutions per year per site, depending on the phase adaptation of the CoV to new hosts.
SARS-CoV-2 husababisha maambukizi kali ya kupumua sawa na SARS-CoV na MERS-CoV, yanayodhihirika kama joto jingi mwilini, kikohozi na ugumu wa kupumua.