The evolutionary origin of MERS-CoV found in bats is known through its initial identification and has also been reinforced by later findings.
Virusi hivi vyote vya HCoV vinavyosambazwa kijamii vimepata njia ya kukaa ndani ya binadamu vyema na vina uwezekano mdogo wa kubadilika ili kusabaisha ugonjwa wa virusi, ingawa ajali zilitokea kwa sababu zisizojulikana kama ilivyo katika visa nadra vya aina ndogo yenye virusi zaidi ya HCoV-NL63, ambavyo hivi majuzi viliripotiwa kusababisha maambukizi kali ya sehemu ya chini ya njia ya kupumua nchini China.