As a transmembrane protein, ACE2 is the main entry point into cells of some coronaviruses, including HCoV-NL63; SARS-CoV (the virus that causes SARS); and SARS-CoV-2 (the virus that causes COVID-19).
Kama protini ya kupitisha utando, ACE2 inatumika kama sehemu kuu ya kuingia kwenye seli za baadhi ya virusi vya korona, ikiwa ni pamoja na HCoV-NL63; SARS CoV (virusi ambavyo vinasababisha SARS); na SARS-CoV-2 (virusi ambavyo vinasababisha COVID-19).