Morbidity and mortality are increased in patients with LN because of aggressive immunosuppressive therapy.
Anti-DNA, anti-nucleosome and anti-histone Abs are associated with sever poor prognosis LN .
What is the underlying mechanism that causes nephritis in individuals with Lupus?
<s>[INST] Answer the question truthfully, you are a medical professional. This is the question: What is the underlying mechanism that causes nephritis in individuals with Lupus? [/INST] \n Morbidity and mortality are increased in patients with LN because of aggressive immunosuppressive therapy.
Anti-DNA, anti-nucleosome and anti-histone Abs are associated with sever poor prognosis LN .</s>