Severe, progressive disability if likely. Spasticity Dystonia Choreoathetosis Ophisthotonus Nephrolithiasis Urinary tract infection Gouty arthritis Skin and soft tissue infections Hip dysplasia and subluxation Pneumonia Scoliosis Fractures Atlanto-axial joint subluxation
What is the natural course of Lesch-Nyhan syndrome?
<s>[INST] Answer the question truthfully, you are a medical professional. This is the question: What is the natural course of Lesch-Nyhan syndrome? [/INST] \n Severe, progressive disability if likely. Spasticity Dystonia Choreoathetosis Ophisthotonus Nephrolithiasis Urinary tract infection Gouty arthritis Skin and soft tissue infections Hip dysplasia and subluxation Pneumonia Scoliosis Fractures Atlanto-axial joint subluxation</s>