The first anatomic description of patent foramen ovale was made by Leonardo da Vinci. He described it as a perforating channel from the left to the right chamber. Julius Friedrich Cohnheim first described the association between patent foramen ovale and stroke.
What does the term patent foramen ovale mean?
<s>[INST] Answer the question truthfully, you are a medical professional. This is the question: What does the term patent foramen ovale mean? [/INST] \n The first anatomic description of patent foramen ovale was made by Leonardo da Vinci. He described it as a perforating channel from the left to the right chamber. Julius Friedrich Cohnheim first described the association between patent foramen ovale and stroke.</s>