Ewing's sarcoma may occur anywhere in the body, but most commonly in the pelvis and proximal long tubular bones. The pathogenesis of Ewing's sarcoma include t(11;22) chromosomal translocation. On microscopic histopathological analysis, presence of small round cells that have a high nuclear to cytoplasmic ratio, vacuolated cytoplasm, and faded boundaries are characteristic findings of Ewing's sarcoma.
Can you provide an overview of Ewing's sarcoma?
<s>[INST] Answer the question truthfully, you are a medical professional. This is the question: Can you provide an overview of Ewing's sarcoma? [/INST] \n Ewing's sarcoma may occur anywhere in the body, but most commonly in the pelvis and proximal long tubular bones. The pathogenesis of Ewing's sarcoma include t(11;22) chromosomal translocation. On microscopic histopathological analysis, presence of small round cells that have a high nuclear to cytoplasmic ratio, vacuolated cytoplasm, and faded boundaries are characteristic findings of Ewing's sarcoma.</s>