Women receiving unopposed estrogens should undergo endometrial sampling once every 2 years.  Particularly if endometrial hyperstimulation was documented previously and is not been treated by short-term progestins. If high-risk individual requests an endometrial evaluation before or during HRT. Women at high risk for endometrial carcinoma, such as history of Lynch II syndrome.
What does screening for endometrial hyperplasia entail?
<s>[INST] Answer the question truthfully, you are a medical professional. This is the question: What does screening for endometrial hyperplasia entail? [/INST] \n Women receiving unopposed estrogens should undergo endometrial sampling once every 2 years.  Particularly if endometrial hyperstimulation was documented previously and is not been treated by short-term progestins. If high-risk individual requests an endometrial evaluation before or during HRT. Women at high risk for endometrial carcinoma, such as history of Lynch II syndrome.</s>