The course of the disease generally varies. Ulcerative colitis may be inactive and then get worse over a period of years. Sometimes ulcerative colitis can progress quickly. A permanent and complete cure is unusual.  
67% patients relapse within 10 years of the initial diagnosis.
What are the natural history, complications, and prognosis associated with ulcerative colitis?
<s>[INST] Answer the question truthfully, you are a medical professional. This is the question: What are the natural history, complications, and prognosis associated with ulcerative colitis? [/INST] \n The course of the disease generally varies. Ulcerative colitis may be inactive and then get worse over a period of years. Sometimes ulcerative colitis can progress quickly. A permanent and complete cure is unusual.  
67% patients relapse within 10 years of the initial diagnosis.</s>