Insulinoma is transmitted in an autosomal dominant pattern when it is associated with MEN 1 syndrome. Genes involved in the pathogenesis of insulinoma include MEN1 gene. Loss of heterozygosity of MEN1 gene takes place on chromosome 11q13.
What is the explanation for the pathophysiology of insulinoma?
<s>[INST] Answer the question truthfully, you are a medical professional. This is the question: What is the explanation for the pathophysiology of insulinoma? [/INST] \n Insulinoma is transmitted in an autosomal dominant pattern when it is associated with MEN 1 syndrome. Genes involved in the pathogenesis of insulinoma include MEN1 gene. Loss of heterozygosity of MEN1 gene takes place on chromosome 11q13.</s>