The most potent risk factor in the development of Buerger's disease is tobacco smoking. Other risk factors include:   
Male sex Rickettsial infection South Asian or Middle Eastern descent Age between 20 - 45 years Medical history of Raynaud's disease or autoimmune disease
What are the factors that increase the risk of developing Buerger's disease?
<s>[INST] Answer the question truthfully, you are a medical professional. This is the question: What are the factors that increase the risk of developing Buerger's disease? [/INST] \n The most potent risk factor in the development of Buerger's disease is tobacco smoking. Other risk factors include:   
Male sex Rickettsial infection South Asian or Middle Eastern descent Age between 20 - 45 years Medical history of Raynaud's disease or autoimmune disease</s>