@NatRevClinOncol @NatRevGastroHep A recent study in @nature showed that inhibition of autophagy in preclinical PDAC models restored surface levels of MHC-I, enhanced anti-tumor T cell responses, and sensitized PDAC to dual ICB (anti-PD-1 + anti-CTLA-4).

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Paper: https://t.co/SdJu8LKpEc https://t.co/HkUYI9D8nn