@icepharma1 @jfais20 The $BMRN data offers 3 ways for $PFE/ $SGMO to be superior in my view:
Safety - no bleeds vs some bleeds;
QOL/cost - no/reduced FVIII replacement SB-525 vs Valo
Durability

All told, with one-time chance at treatment (&amp; one-time $3mm reimb?), pts. may opt for the best not first.