The cover of "Crime and Crime Again" features a black background with white text and a purple border. The title is prominently displayed in large white letters, and the subtitle "Mystery Stories by the World's Great Writers, Including Joyce Carol Oates, Arthur Miller, Norman Mailer, and P.G. Wodehouse" is written in smaller white letters below the title. The cover is edited by Bill Pronzini, Barry N. Malzberg, and Martin H. Greenberg.