There are four families of engineered nucleases: meganucleases, zinc finger nucleases, transcription activator-like effector nucleases (TALENs), and the Cas9-guideRNA system (adapted from CRISPR).
Ilanati ikozat alɣayalan ən nuəléase amotaynen : meganuəleasetan, nuəleasetan wi tisikad ən Zinə, nuəleasetan wi igitan nəmik wan asikar wan transəriɗtion (TALEN) əd əmik wan Cas9-guideRNA (ilmadan CRISPR).