Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to nonsyndromic aplasia cutis congenita ?
    ### Response:
    Nonsyndromic aplasia cutis congenita can have different causes, and often the cause is unknown. Because the condition is sometimes found in multiple members of a family, it is thought to have a genetic component; however, the genetic factors are not fully understood.
    