Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to tetra-amelia syndrome ?
    ### Response:
    Researchers have found a mutation in the WNT3 gene in people with tetra-amelia syndrome from one large family. This gene is part of a family of WNT genes that play critical roles in development before birth. The protein produced from the WNT3 gene is involved in the formation of the limbs and other body systems during embryonic development.
    