Below is an instruction from Human. Write a response.
    ### Instruction:
    How to diagnose Cramp-fasciculation syndrome ?
    ### Response:
    How is cramp-fasciculation syndrome diagnosed?  A diagnosis of cramp-fasciculation syndrome is generally based on the presence of characteristic signs and symptoms. Namely, a history of frequent muscle cramps, twitching, and pain (often worsened by exercise) without muscle weakness or wasting is suggestive of the condition.
    