Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Down syndrome ?
    ### Response:
    What are the signs and symptoms of Down syndrome? People with Down syndrome may develop the following medical problems:  Congenital hypothyroidism Hearing loss Congenital heart defects Seizures Vision disorders Decreased muscle tone (hypotonia) Children with Down syndrome are also more likely to develop chronic respiratory infections, middle ear infections, and recurrent tonsillitis.
    