Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to 5-alpha reductase deficiency ?
    ### Response:
    Mutations in the SRD5A2 gene cause 5-alpha reductase deficiency. The SRD5A2 gene provides instructions for making an enzyme called steroid 5-alpha reductase 2. This enzyme is involved in processing androgens, which are hormones that direct male sexual development.
    