Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Cohen syndrome ?
    ### Response:
    Mutations in the VPS13B gene (frequently called the COH1 gene) cause Cohen syndrome. The function of the protein produced from the VPS13B gene is unknown; however, researchers suggest it may be involved in sorting and transporting proteins inside the cell. Most mutations in the VPS13B gene are believed to prevent cells from producing a functional VPS13B protein.
    