Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Medium-chain acyl-coenzyme A dehydrogenase deficiency ?
    ### Response:
    What causes medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency? Mutations in the ACADM gene cause medium-chain acyl-coenzyme A dehydrogenase deficiency. Mutations in the ACADM gene lead to inadequate levels of an enzyme called medium-chain acyl-coenzyme A dehydrogenase.
    