Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to aromatase excess syndrome ?
    ### Response:
    Rearrangements of genetic material involving the CYP19A1 gene cause aromatase excess syndrome. The CYP19A1 gene provides instructions for making an enzyme called aromatase. This enzyme converts a class of hormones called androgens, which are involved in male sexual development, to different forms of estrogen.
    