Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Mixed connective tissue disease ?
    ### Response:
    What are the signs and symptoms of Mixed connective tissue disease? People with mixed connective tissue disease (MCTD) have symptoms that overlap with several connective tissue disorders, including systemic lupus erythematosus, polymyositis, scleroderma, and rheumatoid arthritis.
    