Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Paget's Disease of Bone ?
    ### Response:
    Paget's disease of bone causes your bones to grow too large and weak. They also might break easily. The disease can lead to other health problems, too, such as arthritis and hearing loss. You can have Paget's disease in any bone, but it is most common in the spine, pelvis, skull, and legs.
    