Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to mucolipidosis III alpha/beta ?
    ### Response:
    Mutations in the GNPTAB gene cause mucolipidosis III alpha/beta. This gene provides instructions for making a part (subunit) of an enzyme called GlcNAc-1-phosphotransferase. This enzyme helps prepare certain newly made enzymes for transport to lysosomes. Lysosomes are compartments within the cell that use digestive enzymes to break down large molecules into smaller ones that can be reused by cells.
    