Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) hand-foot-genital syndrome ?
    ### Response:
    Hand-foot-genital syndrome is a rare condition that affects the development of the hands and feet, the urinary tract, and the reproductive system. People with this condition have abnormally short thumbs and first (big) toes, small fifth fingers that curve inward (clinodactyly), short feet, and fusion or delayed hardening of bones in the wrists and ankles.
    