Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Barth syndrome ?
    ### Response:
    Mutations in the TAZ gene cause Barth syndrome. The TAZ gene provides instructions for making a protein called tafazzin. Tafazzin is located in structures called mitochondria, which are the energy-producing centers of cells. Tafazzin is involved in altering a fat (lipid) called cardiolipin, which plays critical roles in the mitochondrial inner membrane.
    