Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) recombinant 8 syndrome ?
    ### Response:
    Recombinant 8 syndrome is a condition that involves heart and urinary tract abnormalities, moderate to severe intellectual disability, and a distinctive facial appearance. The characteristic facial features include a wide, square face; a thin upper lip; a downturned mouth; a small chin (micrognathia); wide-set eyes (hypertelorism); and low-set or unusually shaped ears.
    