Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Buschke Ollendorff syndrome ?
    ### Response:
    Buschke Ollendorff syndrome (BOS) is a genetic condition of the connective tissue. Common signs and symptoms include non-cancerous skin lumps and spots of increased bone density (which can be seen on X-ray). Some people with BOS have both skin and bone symptoms, while others have one or the other.
    