Below is an instruction from Human. Write a response.
    ### Instruction:
    How many people are affected by tyrosinemia ?
    ### Response:
    Worldwide, tyrosinemia type I affects about 1 in 100,000 individuals. This type is more common in Norway where 1 in 60,000 to 74,000 individuals are affected. Tyrosinemia type I is even more common in Quebec, Canada where it occurs in about 1 in 16,000 individuals.
    