Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to vitamin D-dependent rickets ?
    ### Response:
    The two types of vitamin D-dependent rickets have different genetic causes: CYP27B1 gene mutations cause VDDR1, and VDR gene mutations cause VDDR2. Both genes are involved in the body's response to vitamin D, an important vitamin that can be can be acquired from foods in the diet or made by the body with the help of sunlight.
    