Below is an instruction from Human. Write a response.
    ### Instruction:
    How to diagnose Intrahepatic cholestasis of pregnancy ?
    ### Response:
    How is intrahepatic cholestasis of pregnancy diagnosed? Intrahepatic cholestasis of pregnancy (ICP) is suspected during pregnancy when symptoms of itching (pruritis) present after 25 weeks of gestation with absence of a rash or underlying maternal liver disease.
    