Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) 2-methyl-3-hydroxybutyric aciduria ?
    ### Response:
    2-methyl-3-hydroxybutyric aciduria is an inherited disorder in which the body cannot effectively process the amino acid isoleucine. Signs and symptoms of this condition usually develop in infancy or early childhood and include metabolic acidosis, hypoglycemia, hypotonia, seizures, movement problems, retinal degeneration, and hearing loss.
    