Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to COG5-congenital disorder of glycosylation ?
    ### Response:
    COG5-CDG is caused by mutations in the COG5 gene, which provides instructions for making one piece of a group of proteins known as the conserved oligomeric Golgi (COG) complex. This complex functions in the Golgi apparatus, which is a cellular structure in which newly produced proteins are modified.
    