Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to very long-chain acyl-CoA dehydrogenase deficiency ?
    ### Response:
    Mutations in the ACADVL gene cause VLCAD deficiency. This gene provides instructions for making an enzyme called very long-chain acyl-CoA dehydrogenase, which is required to break down (metabolize) a group of fats called very long-chain fatty acids. These fatty acids are found in foods and the body's fat tissues.
    