Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Paget disease of bone ?
    ### Response:
    What are the signs and symptoms of Paget disease of bone? The Human Phenotype Ontology provides the following list of signs and symptoms for Paget disease of bone. If the information is available, the table below includes how often the symptom is seen in people with this condition.
    