Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Prader-Willi syndrome ?
    ### Response:
    What are the signs and symptoms of Prader-Willi syndrome? In infancy, Prader-Willi syndrome (PWS) is characterized by weak muscle tone (hypotonia), feeding difficulties, poor growth, and delayed development. In later infancy or early childhood, affected children develop an extreme appetite, which leads to overeating and obesity.
    