Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to mucopolysaccharidosis type IV ?
    ### Response:
    Mutations in the GALNS and GLB1 genes cause MPS IV. These genes provide instructions for producing enzymes involved in the breakdown of large sugar molecules called glycosaminoglycans (GAGs). GAGs were originally called mucopolysaccharides, which is where this condition gets its name.
    