Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to ataxia-telangiectasia ?
    ### Response:
    Mutations in the ATM gene cause ataxia-telangiectasia. The ATM gene provides instructions for making a protein that helps control cell division and is involved in DNA repair. This protein plays an important role in the normal development and activity of several body systems, including the nervous system and immune system.
    