Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to familial restrictive cardiomyopathy ?
    ### Response:
    Mutations in several genes have been found to cause familial restrictive cardiomyopathy. Mutations in the TNNI3 gene are one of the major causes of this condition. The TNNI3 gene provides instructions for making a protein called cardiac troponin I, which is found solely in the heart.
    