Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to mucopolysaccharidosis type II ?
    ### Response:
    Mutations in the IDS gene cause MPS II. The IDS gene provides instructions for producing the I2S enzyme, which is involved in the breakdown of large sugar molecules called glycosaminoglycans (GAGs). GAGs were originally called mucopolysaccharides, which is where this condition gets its name.
    