Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to acatalasemia ?
    ### Response:
    Mutations in the CAT gene can cause acatalasemia. This gene provides instructions for making the enzyme catalase, which breaks down hydrogen peroxide molecules into oxygen and water. Hydrogen peroxide is produced through chemical reactions within cells. At low levels, it is involved in several chemical signaling pathways, but at high levels it is toxic to cells.
    