Below is an instruction from Human. Write a response.
    ### Instruction:
    Is amyotrophic lateral sclerosis inherited ?
    ### Response:
    About 90 to 95 percent of ALS cases are sporadic, which means they are not inherited.  An estimated 5 to 10 percent of ALS is familial and caused by mutations in one of several genes. The pattern of inheritance varies depending on the gene involved. Most cases are inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.
    