Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to X-linked infantile spasm syndrome ?
    ### Response:
    X-linked infantile spasm syndrome is caused by mutations in either the ARX gene or the CDKL5 gene. The proteins produced from these genes play a role in the normal functioning of the brain. The ARX protein is involved in the regulation of other genes that contribute to brain development.
    