Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) peroxisomal acyl-CoA oxidase deficiency ?
    ### Response:
    Peroxisomal acyl-CoA oxidase deficiency is a disorder that causes deterioration of nervous system functions (neurodegeneration) beginning in infancy. Newborns with peroxisomal acyl-CoA oxidase deficiency have weak muscle tone (hypotonia) and seizures. They may have unusual facial features, including widely spaced eyes (hypertelorism), a low nasal bridge, and low-set ears.
    