Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Orofaciodigital syndrome 1 ?
    ### Response:
    Orofaciodigital syndrome 1 (OFD1), also called orofaciodigital syndrome type 1, is a condition that affects the development of the oral cavity (the mouth and teeth), facial features, and digits (fingers and toes). This condition also causes polycystic kidney disease.
    