Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to prostate cancer ?
    ### Response:
    Cancers occur when genetic mutations build up in critical genes, specifically those that control cell growth and division or the repair of damaged DNA. These changes allow cells to grow and divide uncontrollably to form a tumor. In most cases of prostate cancer, these genetic changes are acquired during a man's lifetime and are present only in certain cells in the prostate.
    