Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Freeman-Sheldon syndrome ?
    ### Response:
    Freeman-Sheldon syndrome may be caused by mutations in the MYH3 gene. The MYH3 gene provides instructions for making a protein called embryonic skeletal muscle myosin heavy chain 3. This protein belongs to a group of proteins called myosins, which are involved in cell movement and transport of materials within and between cells.
    