Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Charcot-Marie-Tooth disease type 2B ?
    ### Response:
    Charcot-Marie-Tooth disease type 2B (CMT2B) affects the peripheral nerves, the nerves running from outside the brain and spine. Common signs and symptoms include slowly progressive weakness and numbness in the feet, lower leg muscles, hands, and forearms. This type of CMT is also associated with the formation of ulcers in the hands and feet.
    