Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Crigler Najjar syndrome, type 2 ?
    ### Response:
    Crigler Najjar syndrome, type 2 is caused by mutations in the UGT1A1 gene. The gene mutation causes the body to be unable to make adequate enzyme to convert bilirubin into a form that can easily be removed from the body. Without this enzyme, bilirubin can build up in the body and lead to extraordinarily yellow skin and eyes (jaundice).
    