Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Prescription and Illicit Drug Abuse ?
    ### Response:
    Physical dependence is a normal process that can happen to anyone taking a medication for a long time. It means that the body (including the brain) is adapting to the presence of the drug, and the person may require a higher dosage or a different medication to get relief; this condition is known as tolerance.
    