Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Lenz microphthalmia syndrome ?
    ### Response:
    Mutations in at least two genes on the X chromosome are thought to be responsible for Lenz microphthalmia syndrome. Only one of these genes, BCOR, has been identified.  The BCOR gene provides instructions for making a protein called the BCL6 corepressor. This protein helps regulate the activity of other genes.
    