Below is an instruction from Human. Write a response.
    ### Instruction:
    Is prothrombin thrombophilia inherited ?
    ### Response:
    The risk of developing an abnormal clot in a blood vessel depends on whether a person inherits one or two copies of the F2 gene mutation that causes prothrombin thrombophilia. In the general population, the risk of developing an abnormal blood clot is about 1 in 1,000 people per year.
    