Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Angelman Syndrome ?
    ### Response:
    Angelman syndrome is a genetic disorder that causes developmental delay and neurological problems. The physician Harry Angelman first delineated the syndrome in 1965, when he described several children in his practice as having "flat heads, jerky movements, protruding tongues, and bouts of laughter.
    