Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Weill-Marchesani syndrome ?
    ### Response:
    Mutations in the ADAMTS10 and FBN1 genes can cause Weill-Marchesani syndrome. The ADAMTS10 gene provides instructions for making a protein whose function is unknown. This protein is important for normal growth before and after birth, and it appears to be involved in the development of the eyes, heart, and skeleton.
    