Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of What I need to know about Hirschsprung Disease ?
    ### Response:
    The main symptoms of HD are constipation or intestinal obstruction, usually appearing shortly after birth. Constipation in infants and children is common and usually comes and goes, but if your child has had ongoing constipation since birth, HD may be the problem.
    