Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to maternally inherited diabetes and deafness ?
    ### Response:
    Mutations in the MT-TL1, MT-TK, or MT-TE gene cause MIDD. These genes are found in mitochondrial DNA, which is part of cellular structures called mitochondria. Although most DNA is packaged in chromosomes within the cell nucleus, mitochondria also have a small amount of their own DNA (known as mitochondrial DNA or mtDNA).
    