Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Rett syndrome ?
    ### Response:
    Classic Rett syndrome and some variant forms of the condition are caused by mutations in the MECP2 gene. This gene provides instructions for making a protein (MeCP2) that is critical for normal brain function. Although the exact function of the MeCP2 protein is unclear, it is likely involved in maintaining connections (synapses) between nerve cells (neurons).
    