Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the complications of Polycystic Kidney Disease ?
    ### Response:
    Babies with the most severe cases of autosomal recessive PKD often die hours or days after birth because they cannot breathe well enough to sustain life. Their lungs do not develop as they should during the prenatal period. Pressure from enlarged kidneys also contributes to breathing problems.
    