Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to hyperkalemic periodic paralysis ?
    ### Response:
    Mutations in the SCN4A gene can cause hyperkalemic periodic paralysis. The SCN4A gene provides instructions for making a protein that plays an essential role in muscles used for movement (skeletal muscles). For the body to move normally, these muscles must tense (contract) and relax in a coordinated way.
    