Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Pulmonary Embolism ?
    ### Response:
    Major Signs and Symptoms
                
Signs and symptoms of pulmonary embolism (PE) include unexplained shortness of breath, problems breathing, chest pain, coughing, or coughing up blood. An arrhythmia (irregular heartbeat) also may suggest that you have PE.
    