Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Celiac Disease ?
    ### Response:
    Researchers do not know the exact cause of celiac disease. Celiac disease sometimes runs in families. In 50 percent of people who have celiac disease, a family member, when screened, also has the disease.1
                
A person's chances of developing celiac disease increase when his or her genestraits passed from parent to childhave variants, or changes.
    