Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Book syndrome ?
    ### Response:
    What are the signs and symptoms of Book syndrome? To our knowledge, Book syndrome has only been reported in one, large Swedish family (25 cases in 4 generations) and in one other isolated case. The signs and symptoms reported in the Swedish family included premolar aplasia (when the premolars fail to develop); excessive sweating (hyperhidrosis); and early whitening of the hair.
    