Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Mainzer-Saldino syndrome ?
    ### Response:
    Mainzer-Saldino syndrome is usually caused by mutations in the IFT140 gene. This gene provides instructions for making a protein that is involved in the formation and maintenance of cilia, which are microscopic, finger-like projections that stick out from the surface of cells and participate in signaling pathways that transmit information within and between cells.
    