Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to McCune-Albright syndrome ?
    ### Response:
    McCune-Albright syndrome is caused by a mutation in the GNAS gene. The GNAS gene provides instructions for making one part of a protein complex called a guanine nucleotide-binding protein, or a G protein.  In a process called signal transduction, G proteins trigger a complex network of signaling pathways that ultimately influence many cell functions by regulating the activity of hormones.
    