Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Craniometaphyseal dysplasia, autosomal dominant ?
    ### Response:
    What causes autosomal dominant craniometaphyseal dysplasia? Autosomal dominant craniometaphyseal dysplasia is caused by mutations in the ANKH gene. The ANKH gene provides instructions for making a protein that is present in bone and transports a molecule called pyrophosphate out of cells.
    