Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to inherited thyroxine-binding globulin deficiency ?
    ### Response:
    Inherited thyroxine-binding globulin deficiency results from mutations in the SERPINA7 gene. This gene provides instructions for making thyroxine-binding globulin. Some mutations in the SERPINA7 gene prevent the production of a functional protein, causing TBG-CD.
    