Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Microhydranencephaly ?
    ### Response:
    Microhydranencephaly is a developmental abnormality that affects the brain. Signs and symptoms may include extreme microcephaly, scalp rugae (a series of ridges), profound developmental delay and severe intellectual disability. Imaging studies of the brain generally reveal incomplete brain formation and severe hydrocephalus (accumulation of fluid in the brain).
    