Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Sheldon-Hall syndrome ?
    ### Response:
    Sheldon-Hall syndrome can be caused by mutations in the MYH3, TNNI2, TNNT3, or TPM2 gene. These genes provide instructions for making proteins that are involved in muscle tensing (contraction).  Muscle contraction occurs when thick filaments made of proteins called myosins slide past thin filaments made of proteins called actins.
    