Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to ocular albinism ?
    ### Response:
    Ocular albinism type 1 results from mutations in the GPR143 gene. This gene provides instructions for making a protein that plays a role in pigmentation of the eyes and skin. It helps control the growth of melanosomes, which are cellular structures that produce and store a pigment called melanin.
    