Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to frontotemporal dementia with parkinsonism-17 ?
    ### Response:
    FTDP-17 is caused by mutations in the MAPT gene. This gene is located on chromosome 17, which is how the disease got its name.  The MAPT gene provides instructions for making a protein called tau. This protein is found throughout the nervous system, including in nerve cells (neurons) in the brain.
    