Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to thrombocytopenia-absent radius syndrome ?
    ### Response:
    Mutations in the RBM8A gene cause TAR syndrome. The RBM8A gene provides instructions for making a protein called RNA-binding motif protein 8A. This protein is believed to be involved in several important cellular functions involving the production of other proteins.
    