Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) 3-Hydroxyisobutyric aciduria ?
    ### Response:
    3-Hydroxyisobutyric aciduria is a rare metabolic condition in which the body is unable to breakdown certain amino acids (the building blocks of protein). This leads to a toxic buildup of particular acids known as organic acids in the blood (organic acidemia), tissues and urine (organic aciduria).
    