Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Von Willebrand disease ?
    ### Response:
    What causes von Willebrand disease? Von Willebrand disease is typically an inherited disease caused by mutations in the VWF gene. The VWF gene provides instructions for making a blood clotting protein called von Willebrand factor, which is important for forming blood clots and preventing further blood loss after an injury.
    