Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Juvenile amyotrophic lateral sclerosis ?
    ### Response:
    What are the signs and symptoms of juvenile amyotrophic lateral sclerosis? Signs and symptoms of juvenile ALS vary but include slowly to very slowly progressive muscle weakness, increased muscle tone, Babinski reflex, muscle spasm (clonus), exaggerated reflexes, muscle wasting, and muscle twitching.
    