Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Mitochondrial complex II deficiency ?
    ### Response:
    What are the signs and symptoms of Mitochondrial complex II deficiency? The signs and symptoms of mitochondrial complex II deficiency can vary greatly from severe life-threatening symptoms in infancy to muscle disease beginning in adulthood. Many factors affect symptom and symptom severity, including what gene mutation is involved.
    