Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Tylosis with esophageal cancer ?
    ### Response:
    What are the signs and symptoms of Tylosis with esophageal cancer? The main features of Tylosis with esophageal cancer are palmoplantar keratoderma and esophageal cancer. The palmoplantar keratoderma usually begins around age 10, and the soles of the feet are usually more severely affected that the palms of the hands.
    