Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Stickler syndrome ?
    ### Response:
    Stickler syndrome is a group of hereditary conditions characterized by a distinctive facial appearance, eye abnormalities, hearing loss, and joint problems. These signs and symptoms vary widely among affected individuals.  A characteristic feature of Stickler syndrome is a somewhat flattened facial appearance.
    