Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to neuroblastoma ?
    ### Response:
    Neuroblastoma and other cancers occur when a buildup of genetic mutations in critical genesthose that control cell growth and division (proliferation) or maturation (differentiation)allow cells to grow and divide uncontrollably to form a tumor. In most cases, these genetic changes are acquired during a person's lifetime and are called somatic mutations.
    