Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to X-linked lymphoproliferative disease ?
    ### Response:
    Mutations in the SH2D1A and XIAP genes cause XLP. SH2D1A gene mutations cause XLP1, and XIAP gene mutations cause XLP2.  The SH2D1A gene provides instructions for making a protein called signaling lymphocyte activation molecule (SLAM) associated protein (SAP).
    