Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Aicardi-Goutieres syndrome type 4 ?
    ### Response:
    Aicardi-Goutieres syndrome is an inherited condition that mainly affects the brain, immune system, and skin. It is characterized by early-onset severe brain dysfunction (encephalopathy) that usually results in severe intellectual and physical disability. Additional symptoms may include epilepsy, painful, itchy skin lesion (chilblains), vision problems, and joint stiffness.
    