Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) microphthalmia with linear skin defects syndrome ?
    ### Response:
    Microphthalmia with linear skin defects syndrome is a disorder that mainly affects females. In people with this condition, one or both eyes may be very small or poorly developed (microphthalmia). Affected individuals also typically have unusual linear skin markings on the head and neck.
    