Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Farber lipogranulomatosis ?
    ### Response:
    Mutations in the ASAH1 gene cause Farber lipogranulomatosis. The ASAH1 gene provides instructions for making an enzyme called acid ceramidase. This enzyme is found in cell compartments called lysosomes, which digest and recycle materials. Acid ceramidase breaks down fats called ceramides into a fat called sphingosine and a fatty acid.
    