Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to cardiofaciocutaneous syndrome ?
    ### Response:
    Cardiofaciocutaneous syndrome can be caused by mutations in several genes. Mutations in the BRAF gene are most common, accounting for 75 to 80 percent of all cases. Another 10 to 15 percent of cases result from mutations in one of two similar genes, MAP2K1 and MAP2K2.
    