Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Biotin-thiamine-responsive basal ganglia disease ?
    ### Response:
    Biotin-thiamine-responsive basal ganglia disease is a rare condition that affects the brain and other parts of the nervous system. The severity of the condition and the associated signs and symptoms vary from person to person, even within the same family. Without early diagnosis and treatment, most affected people develop features of the condition between ages 3 and 10 years.
    