Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Wilson disease ?
    ### Response:
    What are the signs and symptoms of Wilson disease? Wilson disease can affect many different systems of the body. Affected people often develop signs and symptoms of chronic liver disease in their teenaged years or early twenties. These features may include jaundice; abnormal fluid retention which can lead to swelling of the legs and/or abdomen; weight loss; nausea and vomiting; and/or fatigue.
    