Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) lissencephaly with cerebellar hypoplasia ?
    ### Response:
    Lissencephaly with cerebellar hypoplasia (LCH) affects brain development, resulting in the brain having a smooth appearance (lissencephaly) instead of its normal folds and grooves. In addition, the part of the brain that coordinates movement is unusually small and underdeveloped (cerebellar hypoplasia).
    