Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to nail-patella syndrome ?
    ### Response:
    Mutations in the LMX1B gene cause nail-patella syndrome. The LMX1B gene provides instructions for producing a protein that attaches (binds) to specific regions of DNA and regulates the activity of other genes. On the basis of this role, the LMX1B protein is called a transcription factor.
    