Below is an instruction from Human. Write a response.
    ### Instruction:
    Is primary macronodular adrenal hyperplasia inherited ?
    ### Response:
    People with PMAH caused by ARMC5 gene mutations inherit one copy of the mutated gene in each cell. The inheritance is considered autosomal dominant because one copy of the mutated gene is sufficient to make an individual susceptible to PMAH. However, the condition develops only when affected individuals acquire another mutation in the other copy of the ARMC5 gene in certain cells of the adrenal glands.
    