Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Cornelia de Lange syndrome ?
    ### Response:
    Cornelia de Lange syndrome is a developmental disorder that affects many parts of the body. The features of this disorder vary widely among affected individuals and range from relatively mild to severe.  Cornelia de Lange syndrome is characterized by slow growth before and after birth leading to short stature; intellectual disability that is usually moderate to severe; and abnormalities of bones in the arms, hands, and fingers.
    