Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Dystrophic epidermolysis bullosa ?
    ### Response:
    Dystrophic epidermolysis bullosa (DEB) is one of the major forms of epidermolysis bullosa. The signs and symptoms can vary widely among affected people. In mild cases, blistering may primarily affect the hands, feet, knees, and elbows. Severe cases often involve widespread blistering that can lead to vision loss, disfigurement, and other serious medical problems.
    