Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to complement factor I deficiency ?
    ### Response:
    Complement factor I deficiency is caused by mutations in the CFI gene. This gene provides instructions for making a protein called complement factor I. This protein helps regulate a part of the body's immune response known as the complement system. The complement system is a group of proteins that work together to destroy foreign invaders (such as bacteria and viruses), trigger inflammation, and remove debris from cells and tissues.
    