Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to androgen insensitivity syndrome ?
    ### Response:
    Mutations in the AR gene cause androgen insensitivity syndrome. This gene provides instructions for making a protein called an androgen receptor. Androgen receptors allow cells to respond to androgens, which are hormones (such as testosterone) that direct male sexual development.
    