Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Geroderma osteodysplastica ?
    ### Response:
    Geroderma osteodysplastica is an autosomal recessive disorder characterized by lax, wrinkled skin, loose joints and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia (underdeveloped cheekbones and jaw) and a variable degree of growth deficiency.
    