Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Wolfram syndrome ?
    ### Response:
    Wolfram syndrome is a condition that affects many of the body's systems. The hallmark features of Wolfram syndrome are high blood sugar levels resulting from a shortage of the hormone insulin (diabetes mellitus) and progressive vision loss due to degeneration of the nerves that carry information from the eyes to the brain (optic atrophy).
    