Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of CADASIL ?
    ### Response:
    What are the signs and symptoms of CADASIL? Strokes are the main feature of CADASIL and often occur repeatedly. Strokes may lead to severe disability such as an inability to walk and urinary incontinence. The average age at onset for stroke-like episodes is 46 years.
    