Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Holes in the Heart ?
    ### Response:
    Mothers of children who are born with atrial septal defects (ASDs), ventricular septal defects (VSDs), or other heart defects may think they did something wrong during their pregnancies. However, most of the time, doctors don't know why congenital heart defects occur.
    