Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to WAGR syndrome ?
    ### Response:
    WAGR syndrome is caused by a deletion of genetic material on the short (p) arm of chromosome 11. The size of the deletion varies among affected individuals.  The signs and symptoms of WAGR syndrome are related to the loss of multiple genes on the short arm of chromosome 11.
    