Below is an instruction from Human. Write a response.
    ### Instruction:
    Is pyruvate dehydrogenase deficiency inherited ?
    ### Response:
    Pyruvate dehydrogenase deficiency can have different inheritance patterns. When the condition is caused by mutations in the PDHA1 gene, it is inherited in an X-linked recessive pattern. The PDHA1 gene is located on the X chromosome, which is one of the two sex chromosomes.
    