Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Tetra-amelia syndrome ?
    ### Response:
    Tetra-amelia syndrome is a very rare disorder characterized by the absence of all four limbs. This syndrome can also cause severe malformations of other parts of the body, including the face and head, heart, nervous system, skeleton, and genitalia. The lungs are underdeveloped in many cases, which makes breathing difficult or impossible.
    