Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Emanuel syndrome ?
    ### Response:
    Emanuel syndrome is caused by the presence of extra genetic material from chromosome 11 and chromosome 22 in each cell. In addition to the usual 46 chromosomes, people with Emanuel syndrome have an extra (supernumerary) chromosome consisting of a piece of chromosome 11 attached to a piece of chromosome 22.
    