Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) dihydropyrimidine dehydrogenase deficiency ?
    ### Response:
    Dihydropyrimidine dehydrogenase deficiency is a disorder characterized by a wide range of severity, with neurological problems in some individuals and no signs or symptoms in others.  In people with severe dihydropyrimidine dehydrogenase deficiency, the disorder becomes apparent in infancy.
    