Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Coffin-Siris syndrome ?
    ### Response:
    Coffin-Siris syndrome is a genetic condition that causes variable degrees of learning disability, developmental delays, underdeveloped pinky toenails or fingernails, and distinct facial features. It can be caused by a change (mutation) in any of several genes including the ARID1A, ARID1B, SMARCA4, SMARCB1, or SMARCE1 genes.
    