Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to tyrosinemia ?
    ### Response:
    Mutations in the FAH, TAT, and HPD genes can cause tyrosinemia types I, II, and III, respectively.  In the liver, enzymes break down tyrosine in a five step process, resulting in molecules that are either excreted by the kidneys or used to produce energy or make other substances in the body.
    