Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to hemophilia ?
    ### Response:
    Changes in the F8 gene are responsible for hemophilia A, while mutations in the F9 gene cause hemophilia B. The F8 gene provides instructions for making a protein called coagulation factor VIII. A related protein, coagulation factor IX, is produced from the F9 gene.
    