Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Brittle diabetes ?
    ### Response:
    Brittle diabetes is characterized by severe instability of blood glucose levels with frequent and unpredictable episodes of hypoglycemia and/or ketoacidosis that disrupt quality of life, often requiring frequent or prolonged hospitalizations. These unpredictable episodes are due to an absolute insulin dependency, affecting type 1 diabetics almost exclusively.
    