Below is an instruction from Human. Write a response.
    ### Instruction:
    Is Jacobsen syndrome inherited ?
    ### Response:
    Most cases of Jacobsen syndrome are not inherited. They result from a chromosomal deletion that occurs as a random event during the formation of reproductive cells (eggs or sperm) or in early fetal development. Affected people typically have no history of the disorder in their family, although they can pass the chromosome deletion to their children.
    