Below is an instruction from Human. Write a response.
    ### Instruction:
    Who is at risk for What I need to know about Interstitial Cystitis/Painful Bladder Syndrome? ?
    ### Response:
    Both men and women can get IC/PBS, though twice as many women are affected as men. It can occur at any age, but it is most common in middle age.
                
People with IC/PBS rarely have bladder pain all the time. The pain usually comes and goes as the bladder fills and then empties.
    