Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Imerslund-Grsbeck syndrome ?
    ### Response:
    Mutations in the AMN or CUBN gene can cause Imerslund-Grsbeck syndrome. The AMN gene provides instructions for making a protein called amnionless, and the CUBN gene provides instructions for making a protein called cubilin. Together, these proteins play a role in the uptake of vitamin B12 from food.
    