Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) laryngo-onycho-cutaneous syndrome ?
    ### Response:
    Laryngo-onycho-cutaneous (LOC) syndrome is a disorder that leads to abnormalities of the voicebox (laryngo-), finger- and toenails (onycho-), and skin (cutaneous). Many of the condition's signs and symptoms are related to the abnormal growth of granulation tissue in different parts of the body.
    