Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Isovaleric acidemia ?
    ### Response:
    What causes isovaleric acidemia? Isovaleric acidemia is caused by mutations in the IVD gene. The IVD gene provides instructions for making an enzyme that plays an essential role in breaking down proteins from the diet. Specifically, this enzyme helps process the amino acid leucine, which is part of many proteins.
    