Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Laron syndrome ?
    ### Response:
    Laron syndrome is caused by mutations in the GHR gene. This gene provides instructions for making a protein called the growth hormone receptor. The receptor is present on the outer membrane of cells throughout the body, particularly liver cells. As its name suggests, the growth hormone receptor attaches (binds) to growth hormone; the two proteins fit together like a key in a lock.
    