Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to GRN-related frontotemporal dementia ?
    ### Response:
    GRN-related frontotemporal dementia results from mutations in the GRN gene. This gene provides instructions for making a protein called granulin (also known as progranulin). Granulin is active in many different tissues in the body, where it helps control the growth, division, and survival of cells.
    