Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Tay-Sachs Disease ?
    ### Response:
    Tay-Sachs disease is a rare, inherited disorder. It causes too much of a fatty substance to build up in the brain. This buildup destroys nerve cells, causing mental and physical problems.    Infants with Tay-Sachs disease appear to develop normally for the first few months of life.
    