Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to osteoglophonic dysplasia ?
    ### Response:
    Osteoglophonic dysplasia is caused by mutations in the FGFR1 gene, which provides instructions for making a protein called fibroblast growth factor receptor 1. This protein is one of four fibroblast growth factor receptors, which are related proteins that bind (attach) to other proteins called fibroblast growth factors.
    