Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) corticosteroid-binding globulin deficiency ?
    ### Response:
    Corticosteroid-binding globulin deficiency is a condition with subtle signs and symptoms, the most frequent being extreme tiredness (fatigue), especially after physical exertion. Many people with this condition have unusually low blood pressure (hypotension).
    