Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to hyperparathyroidism-jaw tumor syndrome ?
    ### Response:
    Mutations in the CDC73 gene (also known as the HRPT2 gene) cause hyperparathyroidism-jaw tumor syndrome. The CDC73 gene provides instructions for making a protein called parafibromin. This protein is found throughout the body and is likely involved in gene transcription, which is the first step in protein production.
    