Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to giant congenital melanocytic nevus ?
    ### Response:
    NRAS gene mutations cause most cases of giant congenital melanocytic nevus. Rarely, mutations in the BRAF gene are responsible for this condition.  The proteins produced from these genes are involved in a process known as signal transduction by which signals are relayed from outside the cell to the cell's nucleus.
    