Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Hyper-IgD syndrome ?
    ### Response:
    What are the signs and symptoms of Hyper-IgD syndrome? Hyper IgD syndrome is characterized by periodic high fevers accompanied by lymphadenopathy, abdominal pain, diarrhea, headache, joint pain, hepatomegaly and/or splenomegaly, and skin lesions. Most episodes last several days and occur periodically throughout life.
    