Below is an instruction from Human. Write a response.
    ### Instruction:
    Is isolated lissencephaly sequence inherited ?
    ### Response:
    The inheritance pattern of ILS depends on the gene involved.  When ILS is caused by mutations in the PAFAH1B1 or TUBA1A gene, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.
    