Below is an instruction from Human. Write a response.
    ### Instruction:
    How to diagnose Dihydropyrimidine dehydrogenase deficiency ?
    ### Response:
    How is dihydropyrimidine dehydrogenase (DPD) deficiency diagnosed? DPD deficiency may be diagnosed in various ways. In individuals with complete or profound DPD deficiency, laboratory testing can detect elevated levels of uracil and/or thymine in plasma or urine.
    