Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Warsaw breakage syndrome ?
    ### Response:
    Mutations in the DDX11 gene cause Warsaw breakage syndrome. The DDX11 gene provides instructions for making an enzyme called ChlR1. This enzyme functions as a helicase. Helicases are enzymes that attach (bind) to DNA and temporarily unwind the two spiral strands (double helix) of the DNA molecule.
    