Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Timothy syndrome ?
    ### Response:
    Mutations in the CACNA1C gene are responsible for all reported cases of Timothy syndrome. This gene provides instructions for making a protein that acts as a channel across cell membranes. This channel, known as CaV1.2, is one of several channels that transport positively charged calcium atoms (calcium ions) into cells.
    