Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Hemoglobin E disease ?
    ### Response:
    Hemoglobin E (HbE) disease is an inherited blood disorder characterized by an abnormal form of hemoglobin, called hemoglobin E. People with this condition have red blood cells that are smaller than normal and have an irregular shape. HbE disease is thought to be a benign condition.
    