Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to abetalipoproteinemia ?
    ### Response:
    Mutations in the MTTP gene cause abetalipoproteinemia. The MTTP gene provides instructions for making a protein called microsomal triglyceride transfer protein, which is essential for creating beta-lipoproteins. These lipoproteins are necessary for the absorption of fats, cholesterol, and fat-soluble vitamins from the diet and the efficient transport of these substances in the bloodstream.
    