Below is an instruction from Human. Write a response.
    ### Instruction:
    Is autosomal dominant hyper-IgE syndrome inherited ?
    ### Response:
    AD-HIES has an autosomal dominant pattern of inheritance, which means one copy of an altered gene in each cell is sufficient to cause the disorder. In about half of all cases caused by STAT3 gene mutations, an affected person inherits the genetic change from an affected parent.
    