Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Menkes disease ?
    ### Response:
    Menkes disease is a disorder that affects copper levels in the body. It is characterized by sparse, kinky hair; failure to thrive; and progressive deterioration of the nervous system. Additional signs and symptoms may be present. Children with Menkes syndrome typically begin to develop very severe symptoms during infancy.
    