Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Tropical Spastic Paraparesis ?
    ### Response:
    For several decades the term tropical spastic paraparesis (TSP) has been used to describe a chronic and progressive disease of the nervous system that affects adults living in equatorial areas of the world and causes progressive weakness, stiff muscles, muscle spasms, sensory disturbance, and sphincter dysfunction.
    