Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to short QT syndrome ?
    ### Response:
    Mutations in the KCNH2, KCNJ2, and KCNQ1 genes can cause short QT syndrome. These genes provide instructions for making channels that transport positively charged atoms (ions) of potassium out of cells. In cardiac muscle, these ion channels play critical roles in maintaining the heart's normal rhythm.
    