Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Senior-Lken syndrome ?
    ### Response:
    Senior-Lken syndrome can be caused by mutations in one of at least five genes. The proteins produced from these genes are known or suspected to play roles in cell structures called cilia. Cilia are microscopic, finger-like projections that stick out from the surface of cells; they are involved in signaling pathways that transmit information between cells.
    