Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Multicentric Castleman Disease ?
    ### Response:
    What causes multicentric Castleman disease? The exact underlying cause of multicentric Castleman disease (MCD) is poorly understood. However, some scientists suspect that an increased production of interleukin-6 (IL-6) by the immune system may contribute to the development of MCD.
    