Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to familial lipoprotein lipase deficiency ?
    ### Response:
    Mutations in the LPL gene cause familial lipoprotein lipase deficiency. The LPL gene provides instructions for producing an enzyme called lipoprotein lipase, which is found primarily on the surface of cells that line tiny blood vessels (capillaries) within muscles and fatty (adipose) tissue.
    