Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Roberts syndrome ?
    ### Response:
    Mutations in the ESCO2 gene cause Roberts syndrome. This gene provides instructions for making a protein that is important for proper chromosome separation during cell division. Before cells divide, they must copy all of their chromosomes. The copied DNA from each chromosome is arranged into two identical structures, called sister chromatids.
    