Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Jervell and Lange-Nielsen syndrome ?
    ### Response:
    Mutations in the KCNE1 and KCNQ1 genes cause Jervell and Lange-Nielsen syndrome.  The KCNE1 and KCNQ1 genes provide instructions for making proteins that work together to form a channel across cell membranes. These channels transport positively charged potassium atoms (ions) out of cells.
    