Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Wolff-Parkinson-White syndrome ?
    ### Response:
    Mutations in the PRKAG2 gene cause Wolff-Parkinson-White syndrome.  A small percentage of all cases of Wolff-Parkinson-White syndrome are caused by mutations in the PRKAG2 gene. Some people with these mutations also have features of hypertrophic cardiomyopathy, a form of heart disease that enlarges and weakens the heart (cardiac) muscle.
    