Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to thanatophoric dysplasia ?
    ### Response:
    Mutations in the FGFR3 gene cause thanatophoric dysplasia. Both types of this condition result from mutations in the FGFR3 gene. This gene provides instructions for making a protein that is involved in the development and maintenance of bone and brain tissue.
    