Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Nicolaides-Baraitser syndrome ?
    ### Response:
    Nicolaides-Baraitser syndrome (NCBRS) is a very rare condition characterized by severe intellectual disability and various physical features. Signs and symptoms may include seizures, short stature, sparse hair, distinctive facial characteristics, short fingers and toes (brachydactyly), and prominent joints in the fingers and toes (interphalangeal joints).
    