Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to SOX2 anophthalmia syndrome ?
    ### Response:
    Mutations in the SOX2 gene cause SOX2 anophthalmia syndrome. This gene provides instructions for making a protein that plays a critical role in the formation of many different tissues and organs during embryonic development. The SOX2 protein regulates the activity of other genes, especially those that are important for normal development of the eyes.
    