Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Northern epilepsy ?
    ### Response:
    Mutations in the CLN8 gene cause Northern epilepsy. The CLN8 gene provides instructions for making a protein whose function is not well understood. The CLN8 protein is thought to play a role in transporting materials in and out of a cell structure called the endoplasmic reticulum.
    