Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Transposition of the great arteries ?
    ### Response:
    Transposition of the great arteries (TGA) is a type of congenital heart defect in which there is a reversal of the normal connections of the aorta and the pulmonary artery with the heart. The aorta and pulmonary artery are reversed, which causes oxygen-poor blood to be circulated to the body and oxygen-rich blood to be circulated between the lungs and the heart, rather than to the body.
    