Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) hereditary sensory and autonomic neuropathy type IE ?
    ### Response:
    Hereditary sensory and autonomic neuropathy type IE (HSAN IE) is a disorder that affects the nervous system. Affected individuals have a gradual loss of intellectual function (dementia), typically beginning in their thirties. In some people with this disorder, changes in personality become apparent before problems with thinking skills.
    