Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to histiocytosis-lymphadenopathy plus syndrome ?
    ### Response:
    Histiocytosis-lymphadenopathy plus syndrome is caused by mutations in the SLC29A3 gene, which provides instructions for making a protein called equilibrative nucleoside transporter 3 (ENT3). ENT3 belongs to a family of proteins that transport molecules called nucleosides in cells.
    