Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Charcot-Marie-Tooth disease type 1A ?
    ### Response:
    What are the signs and symptoms of Charcot-Marie-Tooth disease type 1A? CMT1 is generally slowly progressive over many years. However, affected individuals often experience long periods without any obvious deterioration or progression. Occasionally, individuals show accelerated deterioration of function over a few years.
    