Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Dihydrolipoamide dehydrogenase deficiency ?
    ### Response:
    Dihydrolipoamide dehydrogenase (DLD) deficiency is a very rare condition that can vary in age of onset, symptoms and severity. The condition may be characterized by early-onset lactic acidosis and delayed development (most commonly); later-onset neurological dysfunction; or adult-onset isolated liver disease.
    