Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) hypermanganesemia with dystonia, polycythemia, and cirrhosis ?
    ### Response:
    Hypermanganesemia with dystonia, polycythemia, and cirrhosis (HMDPC) is an inherited disorder in which excessive amounts of the element manganese accumulate in the body, particularly in the brain, liver, and blood (hypermanganesemia). Signs and symptoms of this condition can appear in childhood (early-onset), typically between ages 2 and 15, or in adulthood (adult-onset).
    