Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Alstrm syndrome ?
    ### Response:
    Mutations in the ALMS1 gene cause Alstrm syndrome. The ALMS1 gene provides instructions for making a protein whose function is unknown. Mutations in this gene probably lead to the production of an abnormally short, nonfunctional version of the ALMS1 protein.
    