Below is an instruction from Human. Write a response.
    ### Instruction:
    How many people are affected by Alagille Syndrome ?
    ### Response:
    Alagille syndrome occurs in about one of every 30,000 live births.3 The disorder affects both sexes equally and shows no geographical, racial, or ethnic preferences.
                
JAG1 and NOTCH2 gene mutations are inherited in an autosomal dominant way, which means a child can get Alagille syndrome by inheriting either of the gene mutations from only one parent.
    