Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to biotin-thiamine-responsive basal ganglia disease ?
    ### Response:
    Biotin-thiamine-responsive basal ganglia disease is caused by mutations in the SLC19A3 gene. This gene provides instructions for making a protein called a thiamine transporter, which moves thiamine into cells. Thiamine, also known as vitamin B1, is obtained from the diet and is necessary for proper functioning of the nervous system.
    