Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Hemochromatosis ?
    ### Response:
    Primary Hemochromatosis
                
Inherited genetic defects cause primary hemochromatosis, and mutations in the HFE gene are associated with up to 90 percent of cases.1 The HFE gene helps regulate the amount of iron absorbed from food. The two known mutations of HFE are C282Y and H63D.
    