Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) erythrokeratodermia variabilis et progressiva ?
    ### Response:
    Erythrokeratodermia variabilis et progressiva (EKVP) is a skin disorder that is present at birth or becomes apparent in infancy. Although its signs and symptoms vary, the condition is characterized by two major features. The first is areas of hyperkeratosis, which is rough, thickened skin.
    