Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Perry syndrome ?
    ### Response:
    Perry syndrome results from mutations in the DCTN1 gene. This gene provides instructions for making a protein called dynactin-1, which is involved in the transport of materials within cells. To move materials, dynactin-1 interacts with other proteins and with a track-like system of small tubes called microtubules.
    