Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to hypohidrotic ectodermal dysplasia ?
    ### Response:
    Mutations in the EDA, EDAR, and EDARADD genes cause hypohidrotic ectodermal dysplasia.  The EDA, EDAR, and EDARADD genes provide instructions for making proteins that work together during embryonic development. These proteins form part of a signaling pathway that is critical for the interaction between two cell layers, the ectoderm and the mesoderm.
    