Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Freeman-Sheldon syndrome ?
    ### Response:
    Freeman-Sheldon syndrome is a condition that primarily affects the face, hands, and feet. People with this disorder have a distinctive facial appearance including a small mouth (microstomia) with pursed lips, giving the appearance of a "whistling face." For this reason, the condition is sometimes called "whistling face syndrome.
    