Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Combined malonic and methylmalonic aciduria ?
    ### Response:
    Combined malonic and methylmalonic aciduria (CMAMMA) is an inherited condition in which certain chemicals accumulate in the blood and urine of affected individuals. People with CMAMMA can have a wide variety of symptoms. Children with CMAMMA can suffer from developmental delays and a failure to gain weight and grow (failure to thrive).
    