Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) acatalasemia ?
    ### Response:
    Acatalasemia is a condition characterized by very low levels of an enzyme called catalase. Many people with acatalasemia never have any health problems related to the condition and are diagnosed because they have affected family members.  Some of the first reported individuals with acatalasemia developed open sores (ulcers) inside the mouth that led to the death of soft tissue (gangrene).
    