Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) cholesteryl ester storage disease ?
    ### Response:
    Cholesteryl ester storage disease is a rare inherited condition involving the breakdown and use of fats and cholesterol in the body (lipid metabolism). In affected individuals, harmful amounts of lipids accumulate in cells and tissues throughout the body. The liver is most severely affected.
    