Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Protein C deficiency ?
    ### Response:
    What causes protein C deficiency? Protein C deficiency can be inherited or acquired later in life. Inherited protein C deficiency is caused by mutations in the gene that provides instructions for making protein C, called the PROC gene. These mutations disrupt the protein's ability to control blood clotting.
    