Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) myopathy with deficiency of iron-sulfur cluster assembly enzyme ?
    ### Response:
    Myopathy with deficiency of iron-sulfur cluster assembly enzyme is an inherited disorder that primarily affects muscles used for movement (skeletal muscles). This condition does not usually affect other types of muscle, such as the heart (cardiac) muscle.  From early childhood, affected individuals experience extreme fatigue in response to physical activity (exercise intolerance).
    