Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) RAPADILINO syndrome ?
    ### Response:
    RAPADILINO syndrome is a rare condition that involves many parts of the body. Bone development is especially affected, causing many of the characteristic features of the condition.  Most affected individuals have underdevelopment or absence of the bones in the forearms and the thumbs, which are known as radial ray malformations.
    