Below is an instruction from Human. Write a response.
    ### Instruction:
    Is Wolf-Hirschhorn syndrome inherited ?
    ### Response:
    Between 85 and 90 percent of all cases of Wolf-Hirschhorn syndrome are not inherited. They result from a chromosomal deletion that occurs as a random (de novo) event during the formation of reproductive cells (eggs or sperm) or in early embryonic development.
    