Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to sensorineural deafness and male infertility ?
    ### Response:
    Sensorineural deafness and male infertility is caused by a deletion of genetic material on the long (q) arm of chromosome 15. The signs and symptoms of sensorineural deafness and male infertility are related to the loss of multiple genes in this region. The size of the deletion varies among affected individuals.
    