Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to VLDLR-associated cerebellar hypoplasia ?
    ### Response:
    As its name suggests, VLDLR-associated cerebellar hypoplasia results from mutations in the VLDLR gene. This gene provides instructions for making a protein called a very low density lipoprotein (VLDL) receptor. Starting before birth, this protein plays a critical role in guiding the movement of developing nerve cells to their appropriate locations in the brain.
    