Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) 48,XXYY syndrome ?
    ### Response:
    48,XXYY syndrome is a chromosomal condition that causes medical and behavioral problems in males.  48,XXYY disrupts male sexual development. Adolescent and adult males with this condition typically have small testes that do not produce enough testosterone, which is the hormone that directs male sexual development.
    