Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Rabson-Mendenhall syndrome ?
    ### Response:
    Rabson-Mendenhall syndrome results from mutations in the INSR gene. This gene provides instructions for making a protein called an insulin receptor, which is found in many types of cells. Insulin receptors are embedded in the outer membrane surrounding the cell, where they attach (bind) to insulin circulating in the bloodstream.
    