Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Muenke syndrome ?
    ### Response:
    Mutations in the FGFR3 gene cause Muenke syndrome.  The FGFR3 gene provides instructions for making a protein that is involved in the development and maintenance of bone and brain tissue. A single mutation in the FGFR3 gene is responsible for Muenke syndrome.
    