Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to breast cancer ?
    ### Response:
    Cancers occur when a buildup of mutations in critical genesthose that control cell growth and division or repair damaged DNAallow cells to grow and divide uncontrollably to form a tumor. In most cases of breast cancer, these genetic changes are acquired during a person's lifetime and are present only in certain cells in the breast.
    