Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to craniofacial microsomia ?
    ### Response:
    It is unclear what genes are involved in craniofacial microsomia. This condition results from problems in the development of structures in the embryo called the first and second pharyngeal arches (also called branchial or visceral arches). Tissue layers in the six pairs of pharyngeal arches give rise to the muscles, arteries, nerves, and cartilage of the face and neck.
    