Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) 21-hydroxylase deficiency ?
    ### Response:
    21-hydroxylase deficiency is an inherited disorder that affects the adrenal glands. The adrenal glands are located on top of the kidneys and produce a variety of hormones that regulate many essential functions in the body. In people with 21-hydroxylase deficiency, the adrenal glands produce excess androgens, which are male sex hormones.
    