Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Immunodeficiency with hyper IgM type 1 ?
    ### Response:
    Hyper IgM syndrome is a type of primary immunodeficiency syndrome. Primary immunodeficiency occurs when part of a persons immune system is missing or does not work correctly. The bodies of people with primary immunodeficiency cant get rid of germs or protect themselves from new germs as well as they should.
    