Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Townes-Brocks Syndrome ?
    ### Response:
    Mutations in the SALL1 gene cause Townes-Brocks Syndrome. The SALL1 gene is part of a group of genes called the SALL family. These genes provide instructions for making proteins that are involved in the formation of tissues and organs before birth. SALL proteins act as transcription factors, which means they attach (bind) to specific regions of DNA and help control the activity of particular genes.
    