Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Weyers acrofacial dysostosis ?
    ### Response:
    Most cases of Weyers acrofacial dysostosis result from mutations in the EVC2 gene. A mutation in a similar gene, EVC, has been found in at least one person with the characteristic features of the disorder. Little is known about the function of the EVC and EVC2 genes, although they appear to play important roles in cell-to-cell signaling during development.
    