Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Mainzer-Saldino syndrome ?
    ### Response:
    Mainzer-Saldino syndrome is a disorder characterized by kidney disease, eye problems, and skeletal abnormalities.  People with Mainzer-Saldino syndrome have chronic kidney disease that begins in childhood and gets worse over time. The rate at which the kidney disease worsens is variable, but the condition eventually leads to kidney failure in most affected individuals.
    