Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Gilbert syndrome ?
    ### Response:
    Changes in the UGT1A1 gene cause Gilbert syndrome. This gene provides instructions for making the bilirubin uridine diphosphate glucuronosyltransferase (bilirubin-UGT) enzyme, which is found primarily in liver cells and is necessary for the removal of bilirubin from the body.
    