Below is an instruction from Human. Write a response.
    ### Instruction:
    Is Prader-Willi syndrome inherited ?
    ### Response:
    Most cases of Prader-Willi syndrome are not inherited, particularly those caused by a deletion in the paternal chromosome 15 or by maternal uniparental disomy. These genetic changes occur as random events during the formation of reproductive cells (eggs and sperm) or in early embryonic development.
    