Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) CDKL5-related disorder ?
    ### Response:
    A CDKL5-related disorder is a genetic, neuro-developmental condition due to changes (mutations) in the CDKL5 gene. Epileptic encephalopathy (epilepsy accompanied by cognitive and behavioral problems) is the core symptom of a CDKL5-related disorder. Seizures typically begin before 5 months of age.
    