Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Walker-Warburg syndrome ?
    ### Response:
    Walker-Warburg syndrome can be caused by mutations in one of several genes, including POMT1, POMT2, ISPD, FKTN, FKRP, and LARGE. The proteins produced from these genes modify another protein called alpha ()-dystroglycan; this modification, called glycosylation, is required for -dystroglycan to function.
    