Below is an instruction from Human. Write a response.
    ### Instruction:
    How to diagnose Mantle cell lymphoma ?
    ### Response:
    How is Mantle cell lymphoma diagnosed? Mantle cell lymphoma is diagnosed by a biopsy (surgical removal) of the lymph nodes. If lymph nodes are not easily accessible to be biopsied, a fine needle aspiration may be performed, but the diagnosis will not be definite.
    