Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to autoimmune Addison disease ?
    ### Response:
    The cause of autoimmune Addison disease is complex and not completely understood. A combination of environmental and genetic factors plays a role in the disorder, and changes in multiple genes are thought to affect the risk of developing the condition.  The genes that have been associated with autoimmune Addison disease participate in the body's immune response.
    