Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to dyserythropoietic anemia and thrombocytopenia ?
    ### Response:
    Mutations in the GATA1 gene cause dyserythropoietic anemia and thrombocytopenia. The GATA1 gene provides instructions for making a protein that attaches (binds) to specific regions of DNA and helps control the activity of many other genes. On the basis of this action, the GATA1 protein is known as a transcription factor.
    