Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to gray platelet syndrome ?
    ### Response:
    Gray platelet syndrome can be caused by mutations in the NBEAL2 gene. Little is known about the protein produced from this gene. It appears to play a role in the formation of alpha-granules, which are sacs inside platelets that contain growth factors and other proteins that are important for blood clotting and wound healing.
    