Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to X-linked intellectual disability, Siderius type ?
    ### Response:
    X-linked intellectual disability, Siderius type is caused by mutations in the PHF8 gene. This gene provides instructions for making a protein that is found in the nucleus of cells, particularly in brain cells before and just after birth. The PHF8 protein attaches (binds) to complexes called chromatin to regulate the activity (expression) of other genes.
    