Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to atelosteogenesis type 2 ?
    ### Response:
    Atelosteogenesis type 2 is one of several skeletal disorders caused by mutations in the SLC26A2 gene. This gene provides instructions for making a protein that is essential for the normal development of cartilage and for its conversion to bone. Cartilage is a tough, flexible tissue that makes up much of the skeleton during early development.
    