Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Duane-radial ray syndrome ?
    ### Response:
    Duane-radial ray syndrome results from mutations in the SALL4 gene. This gene is part of a group of genes called the SALL family. SALL genes provide instructions for making proteins that are involved in the formation of tissues and organs before birth. The proteins produced from these genes act as transcription factors, which means they attach (bind) to specific regions of DNA and help control the activity of particular genes.
    