Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Miller-Dieker syndrome ?
    ### Response:
    Miller-Dieker syndrome is a condition characterized by a pattern of abnormal brain development known as lissencephaly. Normally the exterior of the brain (cerebral cortex) is multi-layered with folds and grooves. People with lissencephaly have an abnormally smooth brain with fewer folds and grooves.
    