Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) mucolipidosis II alpha/beta ?
    ### Response:
    Mucolipidosis II alpha/beta (also known as I-cell disease) is a progressively debilitating disorder that affects many parts of the body. Most affected individuals do not survive past early childhood.  At birth, children with mucolipidosis II alpha/beta are small and have weak muscle tone (hypotonia) and a weak cry.
    