Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to hyperlysinemia ?
    ### Response:
    Mutations in the AASS gene cause hyperlysinemia. The AASS gene provides instructions for making an enzyme called aminoadipic semialdehyde synthase. This enzyme performs two functions in the breakdown of lysine. First, the enzyme breaks down lysine to a molecule called saccharopine.
    