Below is an instruction from Human. Write a response.
    ### Instruction:
    Is 22q13.3 deletion syndrome inherited ?
    ### Response:
    Most cases of 22q13.3 deletion syndrome are not inherited. The deletion occurs most often as a random event during the formation of reproductive cells (eggs or sperm) or in early fetal development. Affected people typically have no history of the disorder in their family, though they can pass the chromosome deletion to their children.
    