Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Factor V Leiden thrombophilia ?
    ### Response:
    What causes factor V Leiden thrombophilia? Factor V Leiden thrombophilia is caused by a specific mutation in the Factor V gene. Factor V plays a critical role in the formation of blood clots in response to injury.  Genes are our bodys instructions for making proteins.
    