Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Crouzonodermoskeletal syndrome ?
    ### Response:
    Crouzonodermoskeletal syndrome is a disorder characterized by the premature joining of certain bones of the skull (craniosynostosis) during development and a skin condition called acanthosis nigricans.  The signs and symptoms of Crouzonodermoskeletal syndrome overlap with those of a similar condition called Crouzon syndrome.
    