Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Distal chromosome 18q deletion syndrome ?
    ### Response:
    Distal chromosome 18q deletion syndrome is a chromosome abnormality that occurs when there is a missing (deleted) copy of genetic material at the end of the long arm (q) of chromosome 18. The severity of the condition and the signs and symptoms depend on the size and location of the deletion and which genes are involved.
    