Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Autosomal recessive hyper IgE syndrome ?
    ### Response:
    Autosomal recessive hyper IgE syndrome (AR-HIES) is a very rare primary immunodeficiency syndrome characterized by highly elevated blood levels of immunoglobulin E (IgE), recurrent staphylococcal skin abscesses, and recurrent pneumonia. The same features are also seen in the more frequent autosomal dominant HIES syndrome.
    