Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Exstrophy-epispadias complex ?
    ### Response:
    Exstrophy-epispadias complex (EEC) comprises a spectrum of congenital abnormalities that includes epispadias, classical bladder exstrophy and exstrophy of the cloaca and several variants. EEC is characterized by a visible defect of the lower abdominal wall and other problems.
    