Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the complications of Anemia in Chronic Kidney Disease ?
    ### Response:
    Heart problems are a complication of anemia and may include
                
- an irregular heartbeat or an unusually fast heartbeat, especially when exercising.  - the harmful enlargement of muscles in the heart.  - heart failure, which does not mean the heart suddenly stops working.
    