Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Liddle syndrome ?
    ### Response:
    Liddle syndrome is caused by mutations in the SCNN1B or SCNN1G gene. Each of these genes provides instructions for making a piece (subunit) of a protein complex called the epithelial sodium channel (ENaC). These channels are found at the surface of certain cells called epithelial cells in many tissues of the body, including the kidneys, where the channels transport sodium into cells.
    