Below is an instruction from Human. Write a response.
    ### Instruction:
    Is Hypophosphatasia inherited ?
    ### Response:
    How is hypophosphatasia inherited? Perinatal (onset before birth) and infantile hypophosphatasia (HPP) are inherited in an autosomal recessive manner. This means that to be affected, a person must have a mutation in both copies of the responsible gene (ALPL) in each cell.
    