Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Hypertrichosis, hyperkeratosis, mental retardation, and distinctive facial features ?
    ### Response:
    What are the signs and symptoms of Hypertrichosis, hyperkeratosis, mental retardation, and distinctive facial features? The Human Phenotype Ontology provides the following list of signs and symptoms for Hypertrichosis, hyperkeratosis, mental retardation, and distinctive facial features.
    