Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Congenital contractural arachnodactyly ?
    ### Response:
    What causes congenital contractural arachnodactyly? Congenital contractural arachnodactyly is caused by mutations in the FBN2 gene. The FBN2 gene provides instructions for producing the fibrillin-2 protein. Fibrillin-2 binds to other proteins and molecules to form threadlike filaments called microfibrils.
    