Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to X-linked juvenile retinoschisis ?
    ### Response:
    Mutations in the RS1 gene cause most cases of X-linked juvenile retinoschisis. The RS1 gene provides instructions for making a protein called retinoschisin, which is found in the retina. Studies suggest that retinoschisin plays a role in the development and maintenance of the retina.
    