Below is an instruction from Human. Write a response.
    ### Instruction:
    What to do for Primary Sclerosing Cholangitis ?
    ### Response:
    - Primary sclerosing cholangitis (PSC) inflames, scars, and blocks bile ducts inside and outside the liver.  - When bile ducts become blocked, bile builds up in the liver and damages liver cells.  - PSC can lead to vitamin deficiencies, infections, bile duct cancer, cirrhosis, liver failure, and the need for a liver transplant.
    