Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Wiskott-Aldrich syndrome ?
    ### Response:
    Mutations in the WAS gene cause Wiskott-Aldrich syndrome. The WAS gene provides instructions for making a protein called WASP. This protein is found in all blood cells. WASP is involved in relaying signals from the surface of blood cells to the actin cytoskeleton, which is a network of fibers that make up the cell's structural framework.
    