Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Punctate palmoplantar keratoderma type I ?
    ### Response:
    What are the signs and symptoms of Punctate palmoplantar keratoderma type I? Signs and symptoms of punctate palmoplantar keratoderma type 1 tend to become evident between the ages of 10 to 30 years. Symptoms include multiple, tiny, hard rounded bumps of thickened skin on the palms of the hands and soles of the feet.
    