Below is an instruction from Human. Write a response.
    ### Instruction:
    What to do for Gallstones ?
    ### Response:
    - Gallstones are hard particles that develop in the gallbladder.  - Imbalances in the substances that make up bile cause gallstones. Gallstones may form if bile contains too much cholesterol, too much bilirubin, or not enough bile salts. Scientists do not fully understand why these imbalances occur.
    