Below is an instruction from Human. Write a response.
    ### Instruction:
    Is 3-Hydroxyisobutyric aciduria inherited ?
    ### Response:
    Is 3-hydroxyisobutyric aciduria inherited? Cases of 3-hydroxyisobutyric aciduria thought to be caused by changes (mutations) in the ALDH6A1 gene are inherited in an autosomal recessive manner. This means that to be affected, a person must have a mutation in both copies of the responsible gene in each cell.
    