Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to recombinant 8 syndrome ?
    ### Response:
    Recombinant 8 syndrome is caused by a rearrangement of chromosome 8 that results in a deletion of a piece of the short (p) arm and a duplication of a piece of the long (q) arm. The deletion and duplication result in the recombinant 8 chromosome. The signs and symptoms of recombinant 8 syndrome are related to the loss and addition of genetic material on these regions of chromosome 8.
    