Below is an instruction from Human. Write a response.
    ### Instruction:
    What is the outlook for Friedreich's Ataxia ?
    ### Response:
    Generally, within 15 to 20 years after the appearance of the first symptoms, the person is confined to a wheelchair, and in later stages of the disease, individuals may become completely incapacitated. Friedreich's ataxia can shorten life expectancy; heart disease is the most common cause of death.
    