Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Rubinstein-Taybi syndrome ?
    ### Response:
    Mutations in the CREBBP gene are responsible for some cases of Rubinstein-Taybi syndrome. The CREBBP gene provides instructions for making a protein that helps control the activity of many other genes. This protein, called CREB binding protein, plays an important role in regulating cell growth and division and is essential for normal fetal development.
    