Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) uromodulin-associated kidney disease ?
    ### Response:
    Uromodulin-associated kidney disease is an inherited condition that affects the kidneys. The signs and symptoms of this condition vary, even among members of the same family.  Many individuals with uromodulin-associated kidney disease develop high blood levels of a waste product called uric acid.
    