Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Chronic Myelogenous Leukemia ?
    ### Response:
    Most people with CML have a gene mutation (change) called the Philadelphia chromosome. Every cell in the body contains DNA (genetic material) that determines how the cell looks and acts. DNA is contained inside chromosomes. In CML, part of the DNA from one chromosome moves to another chromosome.
    