Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to inclusion body myopathy 2 ?
    ### Response:
    Mutations in the GNE gene cause inclusion body myopathy 2. The GNE gene provides instructions for making an enzyme found in cells and tissues throughout the body. This enzyme is involved in a chemical pathway that produces sialic acid, which is a simple sugar that attaches to the ends of more complex molecules on the surface of cells.
    