Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Graves disease ?
    ### Response:
    Graves disease is thought to result from a combination of genetic and environmental factors. Some of these factors have been identified, but many remain unknown.  Graves disease is classified as an autoimmune disorder, one of a large group of conditions that occur when the immune system attacks the body's own tissues and organs.
    