Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to glutathione synthetase deficiency ?
    ### Response:
    Mutations in the GSS gene cause glutathione synthetase deficiency. The GSS gene provides instructions for making an enzyme called glutathione synthetase. This enzyme is involved in a process called the gamma-glutamyl cycle, which takes place in most of the body's cells.
    