Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Jackson-Weiss syndrome ?
    ### Response:
    Mutations in the FGFR2 gene cause Jackson-Weiss syndrome. This gene provides instructions for making a protein called fibroblast growth factor receptor 2. Among its multiple functions, this protein signals immature cells to become bone cells during embryonic development.
    