Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Salih myopathy ?
    ### Response:
    Salih myopathy is caused by mutations in the TTN gene. This gene provides instructions for making a protein called titin, which plays an important role in skeletal and cardiac muscle function.  Within muscle cells, titin is an essential component of structures called sarcomeres.
    