Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Clouston syndrome ?
    ### Response:
    Clouston syndrome is caused by mutations in the GJB6 gene. This gene provides instructions for making a protein called gap junction beta 6, more commonly known as connexin 30. Connexin 30 is a member of the connexin protein family. Connexin proteins form channels called gap junctions, which permit the transport of nutrients, charged atoms (ions), and signaling molecules between neighboring cells.
    