Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Buschke Ollendorff syndrome ?
    ### Response:
    What are the signs and symptoms of Buschke Ollendorff syndrome? Buschke Ollendorff syndrome (BOS) is an association of connective tissue nevi and osteopoikilosis (small, round areas of increased bone density). The nevi are typically present on the trunk, in the sacrolumbar region (lower back and sacrum), and on the extremities (arms and legs).
    