Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to oculodentodigital dysplasia ?
    ### Response:
    Mutations in the GJA1 gene cause oculodentodigital dysplasia. The GJA1 gene provides instructions for making a protein called connexin43. This protein forms one part (a subunit) of channels called gap junctions, which allow direct communication between cells.
    