Below is an instruction from Human. Write a response.
    ### Instruction:
    What is the outlook for Langerhans Cell Histiocytosis ?
    ### Response:
    LCH in organs such as the skin, bones, lymph nodes, or pituitary gland usually gets better with treatment and is called "low- risk". LCH in the spleen, liver, or bone marrow is harder to treat and is called "high-risk".    The prognosis (chance of recovery) and treatment options depend on the following:          - Whether there are mutations of the BRAF gene.
    