Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to ataxia with vitamin E deficiency ?
    ### Response:
    Mutations in the TTPA gene cause ataxia with vitamin E deficiency. The TTPA gene provides instructions for making the -tocopherol transfer protein (TTP), which is found in the liver and brain. This protein controls distribution of vitamin E obtained from the diet (also called -tocopherol) to cells and tissues throughout the body.
    