Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Birt-Hogg-Dub syndrome ?
    ### Response:
    Mutations in the FLCN gene cause Birt-Hogg-Dub syndrome. This gene provides instructions for making a protein called folliculin. The normal function of this protein is unknown, but researchers believe that it may act as a tumor suppressor. Tumor suppressors prevent cells from growing and dividing too rapidly or in an uncontrolled way.
    