Below is an instruction from Human. Write a response.
    ### Instruction:
    Is Chromosome 3p- syndrome inherited ?
    ### Response:
    Is chromosome 3p- syndrome inherited? In most cases, chromosome 3p- syndrome occurs for the first time in the affected person (de novo mutation). However, the deletion is rarely inherited from a parent. In these cases, the deletion is passed down in an autosomal dominant manner.
    