Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to familial hyperaldosteronism ?
    ### Response:
    The various types of familial hyperaldosteronism have different genetic causes. Familial hyperaldosteronism type I is caused by the abnormal joining together (fusion) of two similar genes called CYP11B1 and CYP11B2, which are located close together on chromosome 8.
    