Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Dentatorubral-pallidoluysian atrophy ?
    ### Response:
    What are the signs and symptoms of Dentatorubral-pallidoluysian atrophy? The signs and symptoms of DRPLA differ somewhat between affected children and adults. When DRPLA appears before age 20, it most often involves episodes of involuntary muscle jerking or twitching (myoclonus); seizures; behavioral changes; intellectual disability; and problems with balance and coordination (ataxia).
    