Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to adenosine deaminase deficiency ?
    ### Response:
    Adenosine deaminase deficiency is caused by mutations in the ADA gene. This gene provides instructions for producing the enzyme adenosine deaminase. This enzyme is found throughout the body but is most active in specialized white blood cells called lymphocytes.
    