Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Pierson syndrome ?
    ### Response:
    Pierson syndrome is a very rare condition that mainly affects the kidneys and eyes. Signs and symptoms include congenital nephrotic syndrome and distinct ocular (eye) abnormalities, including microcoria (small pupils that are not responsive to light). Most affected children have early-onset, chronic renal failure; neurodevelopmental problems; and blindness.
    