Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to pseudocholinesterase deficiency ?
    ### Response:
    Pseudocholinesterase deficiency can be caused by mutations in the BCHE gene. This gene provides instructions for making the pseudocholinesterase enzyme, also known as butyrylcholinesterase, which is produced by the liver and circulates in the blood. The pseudocholinesterase enzyme is involved in the breakdown of choline ester drugs.
    