Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) succinate-CoA ligase deficiency ?
    ### Response:
    Succinate-CoA ligase deficiency is an inherited disorder that affects the early development of the brain and other body systems. One of the earliest signs of the disorder is very weak muscle tone (severe hypotonia), which appears in the first few months of life.
    