Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Trichorhinophalangeal syndrome type 1 ?
    ### Response:
    Trichorhinophalangeal syndrome type 1 (TRPS1) is an extremely rare inherited multisystem disorder. TRPS1 is characterized by a distinctive facial appearance that includes sparse scalp hair; a rounded nose; a long, flat area between the nose and the upper lip (philtrum); and a thin upper lip.
    