Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Mandibulofacial dysostosis with microcephaly ?
    ### Response:
    Mandibulofacial dysostosis with microcephaly (MFDM) is a disorder characterized by developmental delay and abnormalities of the head and face. Affected people are usually born with a small head that does not grow at the same rate as the body (progressive microcephaly).
    