Below is an instruction from Human. Write a response.
    ### Instruction:
    How many people are affected by Polycystic Kidney Disease ?
    ### Response:
    Estimates of PKDs prevalence range from one in 400 to one in 1,000 people.1 According to the United States Renal Data System, PKD accounts for 2.2 percent of new cases of kidney failure each year in the United States. Annually, eight people per 1 million have kidney failure as a result of PKD.
    