Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) N-acetylglutamate synthetase deficiency ?
    ### Response:
    N-acetylglutamate synthase deficiency is type of urea cycle disorder. It causes toxic levels of ammonia to accumulate in the blood. Signs and symptoms in newborns may include a lack of energy, unwillingness to eat, seizures, unusual body movements, and poorly controlled breathing or body temperature.
    