Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to 3-hydroxyacyl-CoA dehydrogenase deficiency ?
    ### Response:
    Mutations in the HADH gene cause 3-hydroxyacyl-CoA dehydrogenase deficiency. The HADH gene provides instructions for making an enzyme called 3-hydroxyacyl-CoA dehydrogenase.  Normally, through a process called fatty acid oxidation, several enzymes work in a step-wise fashion to break down (metabolize) fats and convert them to energy.
    