Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Ehlers-Danlos syndrome, kyphoscoliosis type ?
    ### Response:
    What causes Ehlers-Danlos syndrome, kyphoscoliosis type? Ehlers-Danlos syndrome (EDS), kyphoscoliosis type is caused by changes (mutations) in the PLOD1 gene. This gene encodes an enzyme that helps process molecules which allow collagen to form stable interactions with one another.
    