Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Amish lethal microcephaly ?
    ### Response:
    Mutations in the SLC25A19 gene cause Amish lethal microcephaly.  The SLC25A19 gene provides instructions for producing a protein that is a member of the solute carrier (SLC) family of proteins. Proteins in the SLC family transport various compounds across the membranes surrounding the cell and its component parts.
    