Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Lafora disease ?
    ### Response:
    What are the signs and symptoms of Lafora disease? The signs and symptoms of Lafora disease generally appear during late childhood or adolescence. Prior to the onset of symptoms, affected children appear to have normal development although some may have isolated febrile or nonfebrile convulsions in infancy or early childhood.
    