Below is an instruction from Human. Write a response.
    ### Instruction:
    Who is at risk for Coronary Microvascular Disease? ?
    ### Response:
    Coronary microvascular disease can affect both men and women. However, women may be at risk for coronary microvascular disease if they have lower than normal levels of estrogen at any point in their adult lives. (This refers to the estrogen that the ovaries produce, not the estrogen used in hormone therapy.
    