Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Kuskokwim syndrome ?
    ### Response:
    Kuskokwim syndrome is caused by mutations in the FKBP10 gene, which provides instructions for making the FKBP10 protein (formerly known as FKBP65). This protein is important for the correct processing of complex molecules called collagens, which provide structure and strength to connective tissues that support the body's bones, joints, and organs.
    