Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Legius syndrome ?
    ### Response:
    Legius syndrome is a condition characterized by changes in skin coloring (pigmentation). Almost all affected individuals have multiple caf-au-lait spots, which are flat patches on the skin that are darker than the surrounding area. Another pigmentation change, freckles in the armpits and groin, may occur in some affected individuals.
    