Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to cyclic neutropenia ?
    ### Response:
    Mutations in the ELANE gene cause cyclic neutropenia. The ELANE gene provides instructions for making a protein called neutrophil elastase, which is found in neutrophils. When the body starts an immune response to fight an infection, neutrophils release neutrophil elastase.
    