Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Acanthosis nigricans muscle cramps acral enlargement ?
    ### Response:
    What are the signs and symptoms of Acanthosis nigricans muscle cramps acral enlargement? The Human Phenotype Ontology provides the following list of signs and symptoms for Acanthosis nigricans muscle cramps acral enlargement. If the information is available, the table below includes how often the symptom is seen in people with this condition.
    