Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Polycystic Kidney Disease ?
    ### Response:
    Polycystic kidney disease is a genetic disorder that causes numerous cysts to grow in the kidneys. A kidney cyst is an abnormal sac filled with fluid. PKD cysts can greatly enlarge the kidneys while replacing much of their normal structure, resulting in chronic kidney disease (CKD), which causes reduced kidney function over time.
    