Below is an instruction from Human. Write a response.
    ### Instruction:
    Is Mitochondrial complex II deficiency inherited ?
    ### Response:
    What causes mitochondrial complex II deficiency? Many genes must work together to ensure that the enzyme, complex II (succinate dehydrogenase), can perform its job normally in the body. Changes in the SDHA, SDHB, SDHC, SDHD, SDHAF1, and SDHAF2 genes can all potentially cause complex II deficiency.
    