Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Danon disease ?
    ### Response:
    Danon disease is caused by mutations in the LAMP2 gene. The LAMP2 gene provides instructions for making a protein called lysosomal associated membrane protein-2 (LAMP-2), which, as its name suggests, is found in the membrane of cellular structures called lysosomes.
    