Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to sporadic hemiplegic migraine ?
    ### Response:
    Mutations in the ATP1A2 and CACNA1A genes have been found to cause sporadic hemiplegic migraine. The proteins produced from these genes transport charged atoms (ions) across cell membranes. The movement of these ions is critical for normal signaling between nerve cells (neurons) in the brain and other parts of the nervous system.
    