Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Emanuel syndrome ?
    ### Response:
    Emanuel syndrome is a chromosomal disorder that disrupts normal development and affects many parts of the body. Infants with Emanuel syndrome have weak muscle tone (hypotonia) and fail to gain weight and grow at the expected rate (failure to thrive). Their development is significantly delayed, and most affected individuals have severe to profound intellectual disability.
    