Below is an instruction from Human. Write a response.
    ### Instruction:
    How to prevent Peripheral Arterial Disease (P.A.D.) ?
    ### Response:
    What Causes P.A.D.? The most common cause of P.A.D. is atherosclerosis, a buildup of plaque in the arteries. The exact cause of atherosclerosis isn't known. Certain people are at higher risk for developing atherosclerosis. The disease may start if certain factors damage the inner layers of the arteries.
    