Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to distal hereditary motor neuropathy, type V ?
    ### Response:
    Mutations in the BSCL2 and GARS genes cause distal hereditary motor neuropathy, type V.  The BSCL2 gene provides instructions for making a protein called seipin, whose function is unknown. Mutations in the BSCL2 gene likely alter the structure of seipin, causing it to fold into an incorrect 3-dimensional shape.
    