Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Progressive familial intrahepatic cholestasis type 2 ?
    ### Response:
    Progressive familial intrahepatic cholestasis type 2 (PFIC2) is a rare condition that affects the liver. People with this condition generally develop signs and symptoms during infancy, which may include severe itching, jaundice, failure to thrive, portal hypertension (high blood pressure in the vein that provides blood to the liver) and hepatosplenomegaly (enlarged liver and spleen).
    