Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to juvenile Batten disease ?
    ### Response:
    Most cases of juvenile Batten disease are caused by mutations in the CLN3 gene. This gene provides instructions for making a protein whose function is unknown.  It is unclear how mutations in the CLN3 gene lead to the characteristic features of juvenile Batten disease.
    