Below is an instruction from Human. Write a response.
    ### Instruction:
    How many people are affected by keratoderma with woolly hair ?
    ### Response:
    Keratoderma with woolly hair is rare; its prevalence worldwide is unknown.  Type I (Naxos disease) was first described in families from the Greek island of Naxos. Since then, affected families have been found in other Greek islands, Turkey, and the Middle East.
    