Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Vohwinkel syndrome ?
    ### Response:
    Vohwinkel syndrome is a disorder with classic and variant forms, both of which affect the skin.  In the classic form of Vohwinkel syndrome, affected individuals have thick, honeycomb-like calluses on the palms of the hands and soles of the feet (palmoplantar keratoses) beginning in infancy or early childhood.
    