Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Marfan Syndrome ?
    ### Response:
    Marfan syndrome is a disorder that affects connective tissue. Connective tissues are proteins that support skin, bones, blood vessels, and other organs. One of these proteins is fibrillin. A problem with the fibrillin gene causes Marfan syndrome.     Marfan syndrome can be mild to severe, and the symptoms can vary.
    