Below is an instruction from Human. Write a response.
    ### Instruction:
    Is Pyruvate kinase deficiency inherited ?
    ### Response:
    How is pyruvate kinase deficiency inherited? Pyruvate kinase deficiency is inherited in an autosomal recessive fashion, which means that a child must inherit a gene with a disease-causing mutation from both parents to develop the disorder. The gene that causes pyruvate kinase deficiency is called the PKLR gene that is located on chromosome 1q21.
    