Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Hermansky-Pudlak syndrome ?
    ### Response:
    At least nine genes are associated with Hermansky-Pudlak syndrome. These genes provide instructions for making proteins that are used to make four distinct protein complexes. These protein complexes play a role in the formation and movement (trafficking) of a group of cell structures called lysosome-related organelles (LROs).
    