Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) infantile systemic hyalinosis ?
    ### Response:
    Infantile systemic hyalinosis is a disorder that severely affects many areas of the body, including the skin, joints, bones, and internal organs. Hyalinosis refers to the abnormal accumulation of a clear (hyaline) substance in body tissues. The signs and symptoms of this condition are present at birth or develop within the first few months of life.
    