Below is an instruction from Human. Write a response.
    ### Instruction:
    How many people are affected by X-linked chondrodysplasia punctata 2 ?
    ### Response:
    X-linked chondrodysplasia punctata 2 has been estimated to affect fewer than 1 in 400,000 newborns. However, the disorder may actually be more common than this estimate because it is likely underdiagnosed, particularly in females with mild signs and symptoms.
    