Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) beta-ketothiolase deficiency ?
    ### Response:
    Beta-ketothiolase deficiency is an inherited disorder in which the body cannot effectively process a protein building block (amino acid) called isoleucine. This disorder also impairs the body's ability to process ketones, which are molecules produced during the breakdown of fats.
    