Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to X-linked lissencephaly with abnormal genitalia ?
    ### Response:
    Mutations in the ARX gene cause XLAG. The ARX gene provides instructions for producing a protein that is involved in the development of several organs, including the brain, testes, and pancreas. In the developing brain, the ARX protein is involved with movement and communication in nerve cells (neurons).
    