Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) McKusick-Kaufman syndrome ?
    ### Response:
    McKusick-Kaufman syndrome is a condition that affects the development of the hands and feet, heart, and reproductive system. It is characterized by a combination of three features: extra fingers and/or toes (polydactyly), heart defects, and genital abnormalities.
    