Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to myoclonus-dystonia ?
    ### Response:
    Mutations in the SGCE gene cause myoclonus-dystonia. The SGCE gene provides instructions for making a protein called epsilon ()-sarcoglycan, whose function is unknown. The -sarcoglycan protein is located within the cell membranes of many tissues, but it is most abundant in nerve cells (neurons) in the brain and in muscle cells.
    