Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to dermatofibrosarcoma protuberans ?
    ### Response:
    Dermatofibrosarcoma protuberans is associated with a rearrangement (translocation) of genetic material between chromosomes 17 and 22. This translocation, written as t(17;22), fuses part of the COL1A1 gene from chromosome 17 with part of the PDGFB gene from chromosome 22.
    