Below is an instruction from Human. Write a response.
    ### Instruction:
    What causes Anemia of Inflammation and Chronic Disease ?
    ### Response:
    Anemia of inflammation and chronic disease is caused by red blood cells not functioning normally, so they cannot absorb and use iron efficiently. In addition, the body cannot respond normally to erythropoietin (EPO), a hormone made by the kidneys that stimulates bone marrow to produce red blood cells.
    