Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to pseudohypoaldosteronism type 1 ?
    ### Response:
    Mutations in one of four different genes involved in sodium regulation cause autosomal dominant or autosomal recessive PHA1. Mutations in the NR3C2 gene cause autosomal dominant PHA1. This gene provides instructions for making the mineralocorticoid receptor protein.
    