Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the symptoms of Gout ?
    ### Response:
    Gout is a form of arthritis that frequently affects joints in the lower part of the body such as the knees, ankles, or toes. The affected joint may become swollen, red, or warm. Attacks usually occur at night. Sometime during the course of the disease, many patients will develop gout in the big toe.
    