Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to white sponge nevus ?
    ### Response:
    Mutations in the KRT4 or KRT13 gene cause white sponge nevus. These genes provide instructions for making proteins called keratins. Keratins are a group of tough, fibrous proteins that form the structural framework of epithelial cells, which are cells that line the surfaces and cavities of the body and make up the different mucosae.
    