Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to spinocerebellar ataxia type 2 ?
    ### Response:
    Mutations in the ATXN2 gene cause SCA2. The ATXN2 gene provides instructions for making a protein called ataxin-2. This protein is found throughout the body, but its function is unknown. Ataxin-2 is found in the fluid inside cells (cytoplasm), where it appears to interact with a cell structure called the endoplasmic reticulum.
    