Below is an instruction from Human. Write a response.
    ### Instruction:
    what research (or clinical trials) is being done for Batten Disease ?
    ### Response:
    The biochemical defects that underlie several NCLs have recently been discovered. An enzyme called palmitoyl-protein thioesterase has been shown to be insufficiently active in the infantile form of Batten disease (this condition is now referred to as CLN1).
    