Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to early-onset primary dystonia ?
    ### Response:
    A particular mutation in the TOR1A gene (also known as DYT1) is responsible for most cases of early-onset primary dystonia. The TOR1A gene provides instructions for making a protein called torsinA. Although little is known about its function, this protein may help process and transport other proteins within cells.
    