Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to Hashimoto thyroiditis ?
    ### Response:
    Hashimoto thyroiditis is thought to result from a combination of genetic and environmental factors. Some of these factors have been identified, but many remain unknown.  Hashimoto thyroiditis is classified as an autoimmune disorder, one of a large group of conditions that occur when the immune system attacks the body's own tissues and organs.
    