Below is an instruction from Human. Write a response.
    ### Instruction:
    What is (are) Osteosarcoma and Malignant Fibrous Histiocytoma of Bone ?
    ### Response:
    Key Points
                    - Osteosarcoma and malignant fibrous histiocytoma (MFH) of the bone are diseases in which malignant (cancer) cells form in bone.    - Having past treatment with radiation can increase the risk of osteosarcoma.    - Signs and symptoms of osteosarcoma and MFH include swelling over a bone or a bony part of the body and joint pain.
    