Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to C3 glomerulopathy ?
    ### Response:
    C3 glomerulopathy is associated with changes in many genes. Most of these genes provide instructions for making proteins that help regulate a part of the body's immune response known as the complement system. This system is a group of proteins that work together to destroy foreign invaders (such as bacteria and viruses), trigger inflammation, and remove debris from cells and tissues.
    