Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to cystinuria ?
    ### Response:
    Mutations in the SLC3A1 or SLC7A9 gene cause cystinuria. The SLC3A1 and SLC7A9 genes provide instructions for making the two parts (subunits) of a protein complex that is primarily found in the kidneys. Normally this protein complex controls the reabsorption of certain amino acids, including cystine, into the blood from the filtered fluid that will become urine.
    