Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to hereditary fructose intolerance ?
    ### Response:
    Mutations in the ALDOB gene cause hereditary fructose intolerance. The ALDOB gene provides instructions for making the aldolase B enzyme. This enzyme is found primarily in the liver and is involved in the breakdown (metabolism) of fructose so this sugar can be used as energy.
    