Below is an instruction from Human. Write a response.
    ### Instruction:
    What are the genetic changes related to arrhythmogenic right ventricular cardiomyopathy ?
    ### Response:
    ARVC can result from mutations in at least eight genes. Many of these genes are involved in the function of desmosomes, which are structures that attach heart muscle cells to one another. Desmosomes provide strength to the myocardium and play a role in signaling between neighboring cells.
    