Please consider giving to the Salvation Army.  An uncle, a 442nd veteran, said the Salvation Army gave them food when others didn't.  They're still out there today even thought their bells and kettles aren't welcomed by business and government. There people return value for your contributions.  

Have a good look at and give generously to Médecins Sans Frontières, Doctors Without Borders.  They're big time in developing countries and war zones; the ones whose patients, staff, and hospitals get bombed by both sides.  

As a mentor told me, "Give till it hurts."  It's Christmas!