Some are now saying that the Pope was not even talking Trans people, although that would be stretch given the quotes. The moral question he raises is whether a father can change and how that affects the wife and kids. I guess that depends on what you and the wfe think about lesbianism. Going the other way might be more upsetting to a husband who is not gay but who loves his spouse. People who love their spouses do not want to see them unhappy. There is nothing intrinscally wrong with hormonal therapy that corrects a defect (whether the genes are misaliged or not) and the surgery trasforms, and if successful it is not mutulation. As for loss of childbearing ability, for women, nothing is disgarded. The asexual idealism that condemns sex without a procreative purpose is cultic and is not from Christ.