1st comes people realizing it's a medical / mental health issue
2nd comes people understanding they need to implement harm reduction
3rd comes de-facto decriminalization 
4th comes gov't subsidized clinics that give addicts a safe place to use gov't supplied diamorphine (heroin)

Read about the NAOMI project in Vancouver, or look at the results from the decriminilzation in Portugal a decade ago.... and it's not spelled heroine. A heroine (feminine) is a person or main character of a literary work who, in the face of danger, combats adversity