Ronald, the situation with my granddaughter is too serious for anyone to be humored by it.  If it's taken into consideration that I have reacted similarly 20 years ago, that fact actually paints a different picture on the way how she acquired it.  Certain people are genetically predisposed to react in this way, and no, vaccines are not safe for everyone.  A vaccine with a live virus (not flu)  have triggered my condition (which was transient) and it triggered hers (which might be chronic, as it is more severe, and she received two vaccines concurrently).   I'm surprised that through all the schooling that you have done  you haven't come across some of the work that I have come across as an amateur - if you do come across, you don't have to have a PhD to understand the point of a research.  Most of the time it is written in plain English.  Clear as day, it is there for all scientific and medical community to be ashamed.  And I think that her pediatrician and rheumatologist are ashamed.