Dennism, I am the older sister of a brother who had Down Syndrome . 
If I may say so ...  it's fine to think and say how blessed one is not to have been formed in the womb and born affected by any number of things including Down's .
True , everyone has some "afflictions " .  Had I not had certain strengths I could not have taken care of him in the last years of his life  .  We just acknowledge the way things are and even see the life lessons to be learned from every one of us .  Once in a while he'd carry in the groceries saying , " You help me ? "  when he wanted to convey , May I help you ?  I always got a kick out of it .  He walked the talk having the intellectual level of a two year old and socially about 12 .  His models were our parents who never demanded but rather extended possibilities for him .   Funny thing , his name was George !