So, manic, depressive, manic, depressive,.. over and over. Bipolar disorder responds well to medication that doesn't turn you into a zombie, but the trick is that when manic they feel like superman, and some bipolars don't want to give that up. two weeks of Depakote and Risperdal brings them back to Earth, but do they want to stay there? That's where "choice" comes in. It's got to be tougher than kicking tobacco.