Nicotine poisoning and "green tobacco disease" are a regular occurence. Nicotine is used as pesitcide, like the nerve gases that were repurposed as insecticides, killing life all the way up the food chain to us.

https://www.ecigarettedirect.co.uk/ashtray-blog/2016/10/nicotine-overdose-vaping.html

Nicotine is more poisonous than cynaide.