Excellent Op-ed Dr. Pressler.  I speak as someone who fully supports Medical Marijuana but I also know that everything you say is true, even if the advocates don't want to hear this.  Very unfortunate and unfair to the investors though who have invested so much and still can't bring their product to market.  This needs to be done safely though and it would have been more effective if the advocates and legislators brought the science experts into the process early on rather than long after the bill passed.  Perhaps some of the delays could have been avoided.