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1
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ุจุณู
ุงููู ุงูุฑุญู
ู ุงูุฑุญูู
ุ ุงูุณูุงู
ุนูููู
ูุฑุญู
ุฉ ุงููู
2
00:00:23,800 --> 00:00:29,660
ูุจุฑูุงุชู ูู
ุฑุญุจุงู ุจูู
ุฌู
ูุนูุง. ุณูุชูุงูู ุงูููู
ู
ูุถูุน
3
00:00:29,660 --> 00:00:39,960
ุนูุงู
ุงุช ุชูููู ุงูููุจููุณูุง
4
00:00:39,960 --> 00:00:45,550
ูุงููุงูุจุฑูุงุจููุง. ูู ุงูู
ุญุงุถุฑุฉ ุงูุณุงุจูุฉ ุนุฑููุง ุงูู
5
00:00:45,550 --> 00:00:50,270
hypoxia ููุต ูู ุงูุฃูุณุฌูู ุงูุฏุงุฎู ูู anterior
6
00:00:50,270 --> 00:00:56,010
surface of the corneaุ ูุงูู hypercapnia ุฒูุงุฏุฉ ูู
7
00:00:56,010 --> 00:00:59,910
ุซุงูู ุฃูุณูุฏ ุงููุฑุจูู ุงูุฐู ุฏุงุฎู ูู anterior surface
8
00:00:59,910 --> 00:01:05,670
of the cornea. ู
ู ูุฐู ุงูุนูุงู
ุงุช ุทุจุนูุง ูู ู
ุชุนููุฉ ูููุง
9
00:01:05,670 --> 00:01:11,540
ูู ุงูู corneal epitheliumุ superficial punctate
10
00:01:11,540 --> 00:01:16,460
keratitisุ superficial ุณุทุญู punctate ููุทุฉ
11
00:01:16,460 --> 00:01:19,980
keratitisุ inflammation of the cornea.
12
00:01:22,870 --> 00:01:27,270
ุทุจุนูุง ูููู ุนูุฏู
ุง ูููู
ุจุนู
ู corneal fluorescein staining
13
00:01:27,270 --> 00:01:31,570
ุนูุฏ ุฅุฌุฑุงุก ุงู corneal fluorescein staining ููุงุญุธ ุฃู
14
00:01:31,570 --> 00:01:37,050
ุณุทุญ ุงููุฑููุฉ ูุธูุฑ ุจุงูุดูู ูุฐุง ููุฃูู ููุงุท ุนูู ุงู
15
00:01:37,050 --> 00:01:41,500
corneal epithelium. ูู ุงูู
ุนู
ู ุฃุฎุฐูุง ุงู corneal
16
00:01:41,500 --> 00:01:46,620
staining ููุณู
ูุงูุง ุฅูู grade 0 ู 1 ู 2 ู 3 ูุนุฑููุง
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00:01:46,620 --> 00:01:51,540
ุฃู grade 0 no staining of the corneaุ grade 1 mild
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00:01:51,540 --> 00:01:54,660
staining of the corneal epitheliumุ grade 2
19
00:01:54,660 --> 00:01:57,940
moderate staining of the corneal epitheliumุ ู
20
00:01:57,940 --> 00:02:03,660
grade 3 severe staining of the corneal epithelium.
21
00:02:03,660 --> 00:02:08,340
A premature shedding of small groups of surface
22
00:02:08,340 --> 00:02:15,300
cellsุ ุงูุทุจูุฉ ุฃู ุงูู corneal epithelium ุนูุฏ ุงุฑุชุฏุงุก
23
00:02:15,300 --> 00:02:19,500
ุงูุนุฏุณุฉ ุงููุงุตูุฉ ุณุชุชูุดุฑุ ุฅุฐุง ุณูุญุฏุซ ููุง ููุน ู
ู
24
00:02:19,500 --> 00:02:25,160
ุงูุชูุดุฑุ ุจุงูุชุงูู ุฃู ูู ุณูุญุฏุซ ูููุง ุถุนูุ ูุชูุฌุฉ ู
ุงุฐุง
25
00:02:25,160 --> 00:02:32,200
ูุฐุง ุงูุชูุดุฑุ ุถุนู ุงูุฑูุงุจุท ู
ุง ุจูู ุงูุฎูุงูุง. ุฃูุซุฑ ุดูุก
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00:02:32,200 --> 00:02:36,680
ูุฎุงู ู
ูู ูู ูุฐุง ุงูููุน ูู ู
ูุถูุน ุงู infectionุ
27
00:02:36,680 --> 00:02:40,720
ุงูุนุฏููุ ูู
ุงุฐุงุ ูุฃู ุทุจูุฉ ุงู corneal epithelium ูู
28
00:02:40,720 --> 00:02:45,620
ุชุนุชุจุฑ regenerationุ ูุนูู ุญุชู ูู ุชูุดุฑุช ุจุนุฏ 24 ุณุงุนุฉ
29
00:02:45,620 --> 00:02:50,880
ุณูุญุฏุซ ุนู
ููุฉ ู
ุงุฐุงุ ุชุฌุฏุฏ ููุงุ ูููู ุงูุฎูู ู
ู ุงู
30
00:02:50,880 --> 00:02:54,100
superficial punctate keratitis ูู ู
ูุถูุน ุงู
31
00:02:54,100 --> 00:02:54,520
infection.
32
00:02:57,860 --> 00:03:02,140
ุจุนุฏ ุฐูู ู
ุงุฐุง ุณูุณุจุจุ ุฅุฐุง ุฃูู ุดูุก ุณูุญุฏุซ ุชูุดุฑ ููู
33
00:03:02,140 --> 00:03:05,760
corneal epitheliumุ number two disruption of the
34
00:03:05,760 --> 00:03:11,640
ocular surface mucous layerุ ุฃู ุจู
ุนูู ุนุฑููุฉ ุฃู ูุทุน
35
00:03:11,640 --> 00:03:16,940
ูู
ููุ ููุทุจูุฉ ุงูู
ุฎุงุทูุฉ ุงูุชู ู
ูุฌูุฏุฉ ุฃููุ ูู ุณุทุญ
36
00:03:16,940 --> 00:03:17,480
ุงูุนูู.
37
00:03:20,470 --> 00:03:25,530
ุชุชู
ูุฒ ุงู superficial punctate keratitis ุจุฃููุง
38
00:03:25,530 --> 00:03:31,060
asymptomaticุ ู
ุงุฐุง ูุนูู ุฐููุ ูุนูู ูุง ููุฌุฏ ููุงู ุฃุนุฑุงุถุ
39
00:03:31,060 --> 00:03:35,840
ูุนูู ุงูู
ุฑูุถ ูุง ูุดุนุฑ ุจุฃู ุฃูู
ุ ูุง ููุฌุฏ ุฃูู
ูุดุนุฑ ุจู
40
00:03:35,840 --> 00:03:39,280
ู
ู ุงูู
ุฑูุถุ ูุนูู ูู ูุฃุชู ุนูู ุงูู
ุฑูุฒ ููููู ูู ู
ุซููุง
41
00:03:39,280 --> 00:03:42,500
ูู ุนูุฏู watering ุฃู ูู ุนูุฏู redness ุฃู ูู ุนูุฏู
42
00:03:42,500 --> 00:03:46,740
itchingุ ูุง without painุ ููู ุฃุจุฏุฃ ุจุงูุชุดุงููุงุ ู
ู
43
00:03:46,740 --> 00:03:50,040
ุงู clinical sign of a dry eyeุ ุนุจุงุฑุฉ ุนู ุงู
44
00:03:50,040 --> 00:03:55,100
corneal fluorescein staining. Asymptomatic because
45
00:03:55,100 --> 00:04:00,080
the injury threshold of the cornea is less than
46
00:04:00,080 --> 00:04:05,160
the touch threshold. ุฏุงุฆู
ูุง ููู
ุฉ threshold ู
ุนูุงูุง
47
00:04:05,160 --> 00:04:11,260
ุงุณุชุทุงูุฉ ุฃู ุฅุซุงุฑุฉุ ุฏุงุฆู
ูุง ุนูุฏู
ุง ูููู ุงูุงุณุชุทุงูุฉ ุฃู
48
00:04:11,260 --> 00:04:16,100
ุงูุฅุซุงุฑุฉ ูู ุงูุฃุทุฑุงู ูููู ุฃูู ุชุฃุซูุฑูุง ู
ู ุนูุฏู
ุง ุชููู ูู
49
00:04:16,100 --> 00:04:20,920
ุงูู centerุ ููุฐูู ุงูู
ุฑูุถ ูุง ูุดุนุฑ ุจุฃู ูุฌูุฏ ููุฃูู
.
50
00:04:33,860 --> 00:04:39,820
ู
ูุงุญุธูู ูู ุงูุดูู ุฃู ูุฌูุฏ ุงู staining ุฃููุ ุนูู ุงู
51
00:04:39,820 --> 00:04:45,740
upper partุ ุฃูุถูุง ูู corneal epitheliumุ staining in a
52
00:04:45,740 --> 00:04:47,660
horizontal linear pattern.
53
00:04:51,550 --> 00:04:55,630
close to the superior limbusุ ุณูููู ูุฑูุจ ู
ู ู
ู
54
00:04:55,630 --> 00:04:59,110
ุงูู limbusุ ูุฃูู ูุนุฑู ุฃู ุงู diameter ููุนุฏุณุฉ
55
00:04:59,110 --> 00:05:03,890
ุงููุงุตูุฉ ุงูู soft contact lenses ุณุชุตู ุชูุฑูุจูุง ูู para
56
00:05:03,890 --> 00:05:11,330
limbal. Okayุ the sign is more likely in patients
57
00:05:11,330 --> 00:05:16,290
with tight or low positioning upper lids. ุฏุงุฆู
ูุง
58
00:05:16,290 --> 00:05:19,950
ูุฐู ุชููู ู
ุตุงุญุจุฉ ูู
ูุ ูุฅูุณุงู ุนูุฏู tight
59
00:05:23,140 --> 00:05:31,440
ูู upper eyelid. ูุฐู ุงูููุทุฉ ุงูุฃูููุ ุงูููุทุฉ ุงูุซุงููุฉ
60
00:05:31,440 --> 00:05:42,420
ุฃู ูุฐุง ุงูุดุฎุต ู
ุงุฐุง ูููู ุนูุฏูุ partially tosesุ ุจู
ุนูู
61
00:05:42,420 --> 00:05:46,900
ุฃู ูุง ูุญุฏุซ ููุงู ุฃู ุชูููุฉ ููุฐู ุงูู
ูุทูุฉุ ูุนูู ูุง
62
00:05:46,900 --> 00:05:52,340
ูุฏุฎู ุงู oxygen ุจูู
ูุฉ ูุงููุฉุ ููุฃูู ููุงู close
63
00:05:53,950 --> 00:06:01,010
eyesุ ุฅุบูุงู ูู
ูุ ููุนูููู. Reduced
64
00:06:01,010 --> 00:06:05,750
oxygen availability to the superior region of the
65
00:06:05,750 --> 00:06:10,630
cornea. ุฅุฐุง ุณูุญุฏุซ ููุงู ููุต ูุฏุฎูู ุงู oxygen ูู ูุฐู
66
00:06:10,630 --> 00:06:17,690
ุงูู
ูุทูุฉ. Even in daily contact lens wearุ ุทุจุนูุง hand
67
00:06:17,690 --> 00:06:21,650
daily ุฃู ุจู
ุนูู conventional daily wearุ ูุนูู ุนุฏุณุงุช
68
00:06:21,650 --> 00:06:26,920
ุงููุจุณ ุงูููู
ู ุงูุชูููุฏู. The superior cornea is an
69
00:06:26,920 --> 00:06:31,940
extended wear is covered by the upper lid. ู
ุงุฐุง
70
00:06:31,940 --> 00:06:37,800
ุงูู
ูุตูุฏ ูููุงุ ุฃู ุงูู
ุฑูุถ ูู ููุจุณ ุนุฏุณุงุช ุงููุจุณ ุงูููู
ู
71
00:06:37,800 --> 00:06:41,780
ุงูุชูููุฏูุ ุทุจุนูุง ูุนุฑู ุนุฏุณุงุช ุงููุจุณ ุงูููู
ู
72
00:06:41,780 --> 00:06:48,410
ุงูุชูููุฏู maximum ุณุชุตู ููุฏุงุดุ ุงุซูุชู ุนุดุฑุฉ hoursุ ุตุญูุญุ ุงูุขู
73
00:06:48,410 --> 00:06:53,990
ูุฐุง ุงูู
ุฑูุถ ูุชูุฌุฉ ุฃู ูู ุนูุฏู partially dropping ุฃู
74
00:06:53,990 --> 00:06:59,030
ูู ุนูุฏู tight ูู eyelidุ ููุฃูู ููุจุณ ุนุฏุณุงุช extended
75
00:06:59,030 --> 00:07:03,130
wearุ ุทุจุนูุง ูุนุฑู ุนุฏุณุงุช ุงู extended wear
76
00:07:03,130 --> 00:07:07,650
ุงูู
ุฑูุถ ููุจุณูุง ูู
ุฏุฉ ุฃุณุจูุน ูุงุญุฏุ ูููุงู
ูููุงุ ูุงุฒู
ุฃู
77
00:07:07,650 --> 00:07:11,210
ูููู ูููุง ุงู DK ุนูู T very high compared to mean
78
00:07:12,180 --> 00:07:16,460
conventional daily wearุ ููุฐุง ุงูู
ุฑูุถ ูุชูุฌุฉ ุงู
79
00:07:16,460 --> 00:07:20,720
partially dropping ูู upper eyelid ุฃู ุงู tight ูู
80
00:07:20,720 --> 00:07:24,920
upper eyelid ุณูููู ููุจุณ ุนุฏุณุงุช ุงููุจุณ ุงูููู
ุงูุชูููุฏู
81
00:07:24,920 --> 00:07:29,980
ููู ููุฃูู ูู ุชู
ุซู ู
ุงุฐุงุ extended wear lenses.
82
00:07:29,980 --> 00:07:35,600
ููุญุฏุซ ุนูุฏู ู
ุงุฐุงุ ุงู superior arcuate punctate
83
00:07:35,600 --> 00:07:42,240
staining. ุทูุจ ู
ุงุฐุง ูุฎุชุงุฑุ Superficial punctate
84
00:07:42,240 --> 00:07:47,780
keratitisุ ุฃู
ุงู superior arcuate stainingุ ุทุจุนูุง
85
00:07:47,780 --> 00:07:52,180
ุงูุฃุฎุทุฑ ูู ุงู superiorุ ูุฃู ููุนูุง ู
ุง ุงูู
ุฑูุถ
86
00:07:52,180 --> 00:07:58,340
ูุดุนุฑ ุจูุฌูุฏ ุฃูู
ุ okayุ ููููู ููุงู ุนูุฏู ูุนูู
87
00:07:58,340 --> 00:08:02,320
ุฃุนุฑุงุถ ู
ุตุงุญุจุฉ ูู
ูุ ูู clinical scienceุ ุจุณ ุทุงูู
ุง
88
00:08:02,320 --> 00:08:05,940
ูุดุนุฑ ุจุฃูู
ูู ุชููู ูุฎุฑุ ูุนูู ุณูุฐูุจ ููุทุจูุจ ู
ุจุงุดุฑุ
89
00:08:05,940 --> 00:08:12,980
ุฃููุฏ. ูุฃุ ุฃูุถูุง ุงู superficial punctate keratitis ูู
90
00:08:12,980 --> 00:08:18,780
ูู ุชููู deepุ ูุนูู ุณุชููู ุณุทุญูุฉุ ูู
ู ุงูู
ู
ูู ุนูุงุฌูุงุ ูุนูู
91
00:08:18,780 --> 00:08:21,640
ุจู
ุนูู ุฃูู ุณูููู ุนูุฏู mild corneal fluorescein
92
00:08:21,640 --> 00:08:28,700
stainingุ ูู ุชุตู ููู
oderate ุฃู severeุ ูุฃู ูู ูุฐุง
93
00:08:28,700 --> 00:08:32,500
ุณูููู ู
ุชุนูู ูู ู
ูุ ูู ุงู corneal epitheliumุ ูู
94
00:08:32,500 --> 00:08:37,820
ูููู ูู ุงู stroma ุฃู ุงู endothelium. ุจุงููุณุจุฉ ูู
95
00:08:37,820 --> 00:08:43,000
Epithelial Abrasionุ abrasion ุจู
ุนูู ูุดุท ูู
ูุ ูุทุจูุฉ
96
00:08:43,000 --> 00:08:47,560
ุงูู corneal epithelium. ุงูุขู ูู ูุถุนูุง ูููุฑุณูู
97
00:08:47,560 --> 00:08:52,140
ุณูููู ุจุงูุดูู ูุฐุงุ ุนุจุงุฑุฉ ุนู confluentุ ุฃู ุจู
ุนูู ู
ูุทูุฉ
98
00:08:52,140 --> 00:08:57,280
ู
ุชุฌู
ุนุฉุ ุณุชุชุฌู
ุน ูููุง ูู ุงูู
ูุทูุฉ ูุฐู ุตุจุบุฉ ุงููููุฑุณูู.
99
00:08:57,280 --> 00:09:00,740
Severe
100
00:09:00,740 --> 00:09:04,420
central fluorescein staining resulting
101
00:09:10,500 --> 00:09:16,160
ุฅุฐุง ูู ูุฐู ุงูุญุงูุฉ ุงูู
ุฑูุถ ูุฌุจ ุฃู ูุง ููุจุณ ุงูุนุฏุณุฉุ
102
00:09:16,160 --> 00:09:20,180
ูุงุฒู
ุฃู ุฃูููู ุนู ุงุฑุชุฏุงุก ุงูุนุฏุณุฉ ูู ุงูู
103
00:09:20,180 --> 00:09:21,360
epithelial aberration.
104
00:09:25,750 --> 00:09:31,030
become adherent to the epithelium already weakened
105
00:09:31,030 --> 00:09:36,510
by hypoxia. ุฅุฐุง ู
ุฏุงู
ุงูุนุฏุณุฉ ุชุนู
ู adherence to the
106
00:09:36,510 --> 00:09:41,850
eyeุ ู
ุนูู ุงูููุงู
ุฅู ุงูุนุฏุณุฉ tight lens. ุฅุฐุง ูุงู if
107
00:09:41,850 --> 00:09:46,110
the lens has become adherent to an epitheliumุ ุฅุฐุง
108
00:09:46,110 --> 00:09:52,540
ุงูุนุฏุณุฉ tight lens ุฅูู no sensation at all. Already
109
00:09:52,540 --> 00:09:58,040
weakened by hypoxiaุ ุณูุชู
ููุง ุถุนู ุจููุต ุงู oxygen
110
00:09:58,040 --> 00:10:04,820
ุฃู ุฏุฎูู ุงู oxygen ููุฐู ุงูู
ูุทูุฉ. ุงูุงุจุฑุงุดู ุงููุดุท ูุฐุง
111
00:10:04,820 --> 00:10:10,180
will have sharply demarcatedุ ุณูุนู
ู ุดูู ู
ุฎุทุท ูู
ุง
112
00:10:10,180 --> 00:10:14,080
ูุญู ูุดุงูุฏู ูู ุงููููุฑุณูู. Each and maybe several
113
00:10:14,080 --> 00:10:18,540
millimeters in diameterุ ูุณูููู ูุทุฑ ุดู
ุงูู ูุจูุฑ
114
00:10:18,540 --> 00:10:23,800
ู
ูุงุฑูุฉ ุจุงูู superficial punctate keratitis ุฃู ูู
115
00:10:23,800 --> 00:10:30,180
ุงู superior staining. These
116
00:10:30,180 --> 00:10:35,360
are acute conditions. ุฏุงุฆู
ูุง ูุฐู ู
ุงุฐุง ุชูููุ acute
117
00:10:35,360 --> 00:10:41,480
ุญุงุฏุฉ. Significant discomfort or painุ ุงูู
ุฑูุถ ุณูุดุนุฑ
118
00:10:41,480 --> 00:10:46,080
ุจู ุนุฏู
ุฑุงุญุฉ ูุฃูู
ุดุฏูุฏ. ุทุจุนูุง ู
ุชู ูุฐุง ุงูุฃูู
ุงูุดุฏูุฏ
119
00:10:46,080 --> 00:10:51,020
ูุธูุฑุ ุจุงูุถุจุท ุนูุฏู
ุง ุงูู practitioner ูููู
ุจุนู
ููุฉ
120
00:10:51,020 --> 00:10:53,180
removal ูู soft contact lens.
121
00:10:56,500 --> 00:11:00,940
The lesion is not usually infected by stromal
122
00:11:00,940 --> 00:11:05,980
infiltration is not present. ููุง ูู ูุฐู ุงูุญุงูุฉ ูู
123
00:11:05,980 --> 00:11:11,880
ูุตุงุจ ุงูู
ุฑูุถ ุจุฃู infection ูุฃู ุงูุฃู
ุฑ ูุฐุง ูู ูููู
124
00:11:11,880 --> 00:11:17,800
ุนูุงูุฉ ูู ุงูู stromaุ ูุนูู ูุง ูุคุฐู ุงู stromaุ ูุฏุงุฆู
ูุง
125
00:11:17,800 --> 00:11:21,720
ุงูinfection ูููู ู
ุตุงุญุจ ูู
ูุ ููู stromal.
126
00:11:24,090 --> 00:11:29,070
ุฅุฐุง ูุชู
ูุฒ ูุฐุง ุงูููุน ุตุญูุญ ุจุดุฏุฉ ุฃูู
ูุนุฏู
ุฑุงุญุฉ ููู
ุฑูุถ
127
00:11:29,070 --> 00:11:35,550
ูุฃู ุงูุนุฏุณุฉ ุชููู tight ู
ุน ุงูู epithelium ูุจุณุจุจ hypoxia
128
00:11:35,550 --> 00:11:41,750
ููู rarelyุ ู
ู ุงููุงุฏุฑ ุฃู ูุญุฏุซ infection ููู
ุฑูุถ.
129
00:11:45,900 --> 00:11:51,620
Number fourุ micro cystุ ู vacuousุ micro cyst ู
ุงุฐุง
130
00:11:51,620 --> 00:11:58,760
ู
ุนูุงูุงุ ูู ููุณุ ู vacuous ุจู
ุนูู ูุฑุงุบุงุชุ ุทุจุนูุง ูููู
131
00:11:58,760 --> 00:12:05,060
ุจุงูุดูู ูุฐุงุ ุงูููุงุท ุงูุจูุถุงุกุ ูู
ูุทูุชูุง ูุนูู ูููู ุงู
132
00:12:05,060 --> 00:12:13,130
area ูู ุงู superior part ูู ุงูุบุงูุจ. Translucent cystุ
133
00:12:13,130 --> 00:12:17,730
ุฃู ุจู
ุนูู ุงููู ูู ุฃููุงุณ ุชููู ุดุจู ุดูุงูุฉ in the
134
00:12:17,730 --> 00:12:23,790
epitheliumุ 0.01 to 0.1 millimeter in diameter. ุฅุฐุง
135
00:12:23,790 --> 00:12:28,790
ูุทุฑูุง ู
ุงุฐุง ููุงุญุธูุ ุฃูู very smallุ ููุฐุง ูุนุทููู
136
00:12:28,790 --> 00:12:33,950
indicatorุ ู
ุคุดุฑ ุฃูู ูุง ูู
ูู ุฑุคูุชูุง ุจุงูุนูู ุงูู
ุฌุฑุฏุฉ.
137
00:12:33,950 --> 00:12:41,740
ุฅุฐุง ุชุญุชุงุฌ ู
ุงุฐุงุ microscope. ูู ููุงู ุทุฑููุฉ ู
ู ุฎูุงู
138
00:12:41,740 --> 00:12:46,400
ุงูู retro illumination ูู
ูู ุฃู ุฃุฑู ูุฐู ุงูุฃููุงุณุ
139
00:12:46,400 --> 00:12:52,500
ูููู ุชุญุชุงุฌ ูุฎุจุฑุฉ ูุจูุฑุฉ ู
ู ุงู examiner. ุทูุจ ุฃูุง ู
140
00:12:52,500 --> 00:12:56,580
beginnerุ ู
ุจุชุฏุฆุ ููู ุฃุนุฑู ุฃู ูุฐุง ุงูู
ุฑูุถ ุนูุฏู micro
141
00:12:56,580 --> 00:13:01,160
zest ุฃู ุงูุชุดู ูุฐุง ุงูุฃู
ุฑุ ุงูุจุณุงุทุฉ ุฃูู ุฃุนู
ู ุงู
142
00:13:01,160 --> 00:13:06,120
corneal fluorescein staining ู
ู
ูู ุฃููู ูุฏููู ุงูุทุจุงุน
143
00:13:06,120 --> 00:13:09,820
ุฃู ู
ุคุดุฑ ุฅุฐุง ุงูู
ุฑูุถ ูุงู ุนูุฏู micro zest
144
00:13:13,110 --> 00:13:24,990
ุงูู
ููุฑูุฒููุณ ุตุบูุฑ ููููู ู
ู ุงููุฌูุงุช ุจุดูู
145
00:13:28,460 --> 00:13:33,120
destination is uncertain ุงูุชููุชููุงุช ุบูุฑ ู
ุญุฏุฏุฉ ุงู
146
00:13:33,120 --> 00:13:38,160
function ููู
ูุนูู ูุญุฏ ุงูุขู ุงู micro zest ู ุงู
147
00:13:38,160 --> 00:13:43,240
vacuous ุงูุชููุชููุงุช without function ุจุฏูู ุฃู ูุธููุฉ
148
00:13:45,730 --> 00:13:50,090
It takes 6 to 8 weeks of extended wear with
149
00:13:50,090 --> 00:13:55,990
hydrogel lenses before micro-zest appear ุฏุงุฆู
ุงู
150
00:13:55,990 --> 00:14:01,810
ุจุชุฃุฎุฐ ู
ุฏุฉ ู
ู 6 ู 8 ุฃุณุงุจูุน ูุธููุฑ ู
ู ุงู micro-zest
151
00:14:01,810 --> 00:14:07,090
ุฃู ุงู vaculus ุทุจ ูู ูู ุจุชุชุนูู ูู ุงู
152
00:14:07,090 --> 00:14:11,090
daily wear ุฃูุตุฏ ุงููู ูู ุงู daily disposable lenses
153
00:14:11,090 --> 00:14:14,250
ููุง ุงู extended wear ููุง ุงู conventional daily
154
00:14:14,250 --> 00:14:18,550
wearููุง ุนูุงูุฉ ูู ุงู extended wear ู ุงู
155
00:14:18,550 --> 00:14:22,230
conventional daily wear ูููุ ูุฃููู ุจู
ุนูู ูู
156
00:14:22,230 --> 00:14:25,370
chronicุ ู
ุง ุจุชูุฌู ุจุดูู ุฃููู ู
ูุงุฌุฆ
157
00:14:30,010 --> 00:14:35,410
One clue ูุนูู ูุงุญุฏุฉ ู
ู ุงูุฃููุงุฑ to the presence
158
00:14:35,410 --> 00:14:41,630
ูุธููุฑ of microcyst or vacuous may be scattered by
159
00:14:41,630 --> 00:14:45,150
nectarine fluorocene staining ุฒู ู
ุง ุงุชูููุง ุฃู
160
00:14:45,150 --> 00:14:50,170
ูุงุญุฏุฉ ู
ู ุงูุญููู ุฃู ูุงุญุฏุฉ ู
ู ุงูู
ุคุดุฑุงุช ุฃู ูุฐุง ุงูู
ุฑูุถ
161
00:14:50,170 --> 00:14:55,250
ุนูุฏู microcyst ุฃู vacuous ู
ู ุฎูุงู ุฃููู ุฃู ุงุณุชุฎุฏู
162
00:14:55,250 --> 00:14:56,470
ุงููุฑููุฉ ููููุฑูุณูู
163
00:14:59,640 --> 00:15:05,760
ูุนูู ูุฌูุฏูุง ุฃู ุนุฏู
ูุฌูุฏูุง ุทุจุนุงู ุงูุฃุฑุจุนุฉ ูุฏูู ูุง
164
00:15:05,760 --> 00:15:11,100
ููุนุชุจุฑูู ู
ุฎููุงุช ุจุดูู ูุจูุฑ ูุฃู ู
ููุนูู
ููู ููู ูู ุงู
165
00:15:11,100 --> 00:15:16,180
corneal epithelia management
166
00:15:16,180 --> 00:15:20,620
ุฃูู ุจู
ุนูู ุงูุนูุงุฌ ุฃู ุขููุฉ ุงูุนูุงุฌ ุฃู ุงูุทุฑููุฉ
167
00:15:20,620 --> 00:15:26,460
significant epithelial staining ุงูู
ูุตูุฏ ูููุง ุฅู
ูุง
168
00:15:26,460 --> 00:15:34,390
moderate ุฃู severe24 hour discontinuation of lens
169
00:15:34,390 --> 00:15:38,770
wear ุฅุฐุง ุงูุดุฎุต ูุงู ุนูุฏู severe ุฃู moderate
170
00:15:38,770 --> 00:15:43,650
staining ูุธูุฑ ุนูุฏู ุงูุญุงูุงุช ูุฏูู ุงูุฃุฑุจุนุฉ ุจุนู
ู ุนู
ููุฉ
171
00:15:43,650 --> 00:15:49,150
ุชูููู ูุงุฑุชุฏุงุก ุงูุนุฏุณุฉ ูู
ุฏุฉ 24 ุณุงุนุฉ ูู ุฃูุด ุจููุตุฏ ุงู
172
00:15:49,150 --> 00:15:53,210
conventional daily wear ุทุจุนุงู ุฅุฐุง ูุงูุช extended
173
00:15:53,210 --> 00:15:58,430
wear ุฃู daily disposable lenses ุจูููููุง ุจุดูู ุฃูููุ
174
00:15:58,430 --> 00:16:04,190
ูุงู
ู ู
ุฑุฉ ุชุงููุฉุ ุงูุขู ุฅุฐุง ูุงู ุงูู
ุฑูุถ ุนูุฏู moderate
175
00:16:04,190 --> 00:16:07,930
ุฃู severe staining ููุงู ุจููุจุณ conventional daily
176
00:16:07,930 --> 00:16:16,090
wear ุจููู ุงุฑุชุฏุงุก ุงูุนุฏุณุฉ ูู
ุฏุฉ ูุฏูุ 24 ุณุงุนุฉ ุทุจุนุงู ุฅุฐุง
177
00:16:16,090 --> 00:16:19,630
ุธูุฑุช ุนูุฏู ุงูุฃุฑุจุน ุญุงูุงุช ูุฏูู ุงู superfacial
178
00:16:19,630 --> 00:16:23,230
panictate keratitis ุฃู ุงู superior arcuate
179
00:16:23,230 --> 00:16:27,130
panictate staining ุฃู epithelial aberration ุฃู ุงู
180
00:16:27,130 --> 00:16:34,370
micro zestุฅุฐุง ู
ุง ุธูุฑูุง ุฎูุงุต ุฃู ุงูู
ุฑูุถ ุจูุณุชู
ุฑ ูู
181
00:16:34,370 --> 00:16:39,810
ุงุฑุชุฏุงุก ุงูุนุฏุณุฉ ุทูุจ ุจุนุถ ุงูุฃุญูุงู ุฃูุช ุจุชุนู
ู ุงููุญุต ูููู
182
00:16:39,810 --> 00:16:44,250
ุฃููู ุจูุตูุฑ ุฃููู ุงููู ูู absent ุบูุงุจ ุฅููุง ูุนูู ุจู
ุนูู
183
00:16:44,250 --> 00:16:48,330
ุงูุขู ุฃูุง ุชูููุช ุฃุฑุจุน ูุนุดุฑูู ุณุงุนุฉ ุนู ุงุฑุชุฏุงุก ุงูุนุฏุณุฉ
184
00:16:48,330 --> 00:16:51,650
ุฑุญุช ุนู
ูุช corneal florescence stain ู
ุฑุฉ ุชุงููุฉ
185
00:16:51,650 --> 00:16:56,350
ู
ุง ุธูุฑุด ุงูุจุงููุชูุช ููุฑูุชุงูุชุณ ุฃูุด ุจุฏู ุฃุนู
ู ูู ูุฐู
186
00:16:56,350 --> 00:17:01,480
ุงูุญุงูุฉุ ุจุฑุฌุน ุฃูุจุณ ุงูุนุฏุณุฉูููู ุฅุฐุง ูุงู ูุฐุง ุงูู
ุฑูุถ
187
00:17:01,480 --> 00:17:07,440
ุจููุจุณ extended wear ุฃู daily disposable lensesุ ุจุฏู
188
00:17:07,440 --> 00:17:11,640
ูุชููู ุจุดูู ูุงู
ูุ ูู ุญุงูุฉ ู
ููุ ุงูู significant
189
00:17:11,640 --> 00:17:18,340
stainingุ ุงููู ูู ุงู moderate ุฃู ุงูุณูููุฑุ mild
190
00:17:18,340 --> 00:17:25,220
staining ูุนูู grade oneุ reducing wearing timeุ
191
00:17:25,220 --> 00:17:30,340
ุจุฏูุง ูููู ู
ู ุณุงุนุงุช ุงุฑุชุฏุงุก ุงูุนุฏุณุฉfor example to
192
00:17:30,340 --> 00:17:35,720
less than ten hours beer day or ceasing extended
193
00:17:35,720 --> 00:17:36,040
wear
194
00:17:41,320 --> 00:17:45,460
ุจูููู ูู ููุท ูุจุณ ุงูุนุฏุณุฉ ุฃุฑุจุน ุณุงุนุงุช ุฃู ุณุงุนุชูู ุฃู
195
00:17:45,460 --> 00:17:50,880
ุซูุงุซุฉ ูุนูู ุงูู
ูู
ุฃููู ุฃููู ู
ู ุนุฏุฏ ูุนูู ุฃููู ุงููู ูู
196
00:17:50,880 --> 00:17:54,700
ุนุฏุฏ ุงูุณุงุนุงุช ุงุฑุชุฏุงุก ุงูุนุฏุณุฉ ุทุจ ูู ูุงูุช extended
197
00:17:54,700 --> 00:17:59,880
wear ุฃู daily disposable lenses ุจูููููุง ุจุดูู ูุงู
ู
198
00:17:59,880 --> 00:18:04,080
ุญุชู ูู ุงู mild ุญุชู ูู ุงู mild staining ูููุ ูุฃูู ุงู
199
00:18:04,080 --> 00:18:07,440
mild staining ูู ูุจุณ ุงูุนุฏุณุฉ ูู
ุฏุฉ ุฃุณุจูุน ุจูุตูุฑ
200
00:18:07,440 --> 00:18:08,400
moderate ุฃู severe
201
00:18:12,570 --> 00:18:16,250
if the staining is chronic ูุนูู ูุฐุง ูุงู ุงู
202
00:18:16,250 --> 00:18:20,050
staining ู
ุถู
ู ุนูุฏ ุงูุดุฎุต ู
ู ูุจู ุญุชู ู
ุง ูุฑุชุฏู ุนุฏุณุฉ
203
00:18:20,050 --> 00:18:25,170
ูุงุตูุฉ even if it's light or mild ุญุชู ูู ูุงู ุจุณูุท
204
00:18:25,170 --> 00:18:30,770
modification ุฃูู ุจู
ุนูู ุชุนุฏูู of lens parameters ุฃูุง
205
00:18:30,770 --> 00:18:35,650
ุจุฏู ุฃุนู
ู ุนู
ููุฉ ุชุนุฏูู ูู
ููุ ูู parameters ุงููู ุฎุงุตุฉ
206
00:18:35,650 --> 00:18:42,370
ูู ุงูุนุฏุณุฉ to increase dk ุนูู t is advisableุทุจ ูุฐุง
207
00:18:42,370 --> 00:18:55,410
ุงูููุงู
ู
ู
ูู ูููู ุฎุทุฃ ุตุญุ ู
ูู ุจุชูู ู
ุนุงูุงุ ู
ู
ุชุงุฒุฉ
208
00:18:55,410 --> 00:19:01,090
ุจุงูุถุจุทุ ูุนูู ุงูุขู ู
ุซูุงู ุดุฎุต ูุงู ุนูุฏู dry eye ูู ุจุนุถ
209
00:19:01,090 --> 00:19:05,150
ุงูุฃุญูุงู ูุฏ ูููู ู
ุตุงุญุจ ูู ุฃูููุ ุงู corneal
210
00:19:05,150 --> 00:19:10,430
fluorescein staining ุฑุญุช ุฃูุง ุฒูุฏุช ุงู DK ุนูู Tุฃูุด
211
00:19:10,430 --> 00:19:15,770
ุตุงุฑุ ุฒูุฏ ุงูุฌูุงู ูุนูู ุงู dry eye symptoms ุตุงุฑ ุฃูุซุฑ
212
00:19:15,770 --> 00:19:20,270
ุธููุฑ ููุฐุง ุงูุดุฎุต ูุฃูุง ุฃูุด ุนู
ูุช ูู ูุฐู ุงูุญุงูุฉุ ุฃุณุฃุช
213
00:19:20,270 --> 00:19:25,130
ุงููู ูู ุฃูุซุฑ ูู ุงู patient ูุงุถุญุฉ ุงูููุฑุฉุ ูุฏุงูู
ุงู ุงู
214
00:19:25,130 --> 00:19:30,130
parameters ู
ุด ุงูู
ูุตูุฏ ูููุง ุงููู ูู ุฃููู ููุท ุฃุฒูุฏ ุงู
215
00:19:30,130 --> 00:19:34,930
DK ุนูู T ูุง ูุงุฒู
ุฃูุง ุฃุฑุงุนู ูู ุงูุธุฑูู ูุนูู ู
ู
ูู ุฃูุง
216
00:19:34,930 --> 00:19:40,660
ุฃุบูุฑ ุงู thickness ุฏูู ุชุบููุฑ ู
ููุ ุงู DK ุนูู Tููู
217
00:19:40,660 --> 00:19:44,680
ุทูุจุ ู
ู
ูู ู
ุซูุงู ูู ุจููุจุณ low water content ุจุฎููู
218
00:19:44,680 --> 00:19:48,000
medium water content ูููู ุจููู ุงู mean ุงู
219
00:19:48,000 --> 00:19:53,520
thickness ูุฏุงูู
ุงู ูุนูู ุงุฎุชูุงุฑ ุงู option ู
ูู
ูุซูุฑ ูู
220
00:19:53,520 --> 00:19:54,720
ุฌู
ูุน ุงูุธุฑูู
221
00:19:59,590 --> 00:20:04,630
Superior arcuate panectate staining may require an
222
00:20:04,630 --> 00:20:09,850
improvement to peripheral lensุ DK ุนูู T ููุฐุง ุฃู
ุฑ
223
00:20:09,850 --> 00:20:16,190
ุทุจูุนู ูุฃููู ูู ุนูุฏู tight upper eyelid ุฃู ูู ุนูุฏู ..
224
00:20:16,190 --> 00:20:21,830
ูู ุนูุฏู partially toses ููู ูุฐู ุงูุญุงูุฉ ุฃูุง ุฃูุด ุจุฏู
225
00:20:21,830 --> 00:20:27,440
ุฃุนู
ูุ ุฃุฒูุฏ ุงููDK ุนูู T ู
ู ุงูุฃุทุฑุงู ุนุดุงู ุฃูุด ูุนู
ู
226
00:20:27,440 --> 00:20:33,200
ุฒูุงุฏุฉ ูุฏุฎูู ุงู oxygen ูููุ ูู ุงูุฃุทุฑุงู whereas
227
00:20:33,200 --> 00:20:38,240
ุจููู
ุง central staining may indicate the need to
228
00:20:38,240 --> 00:20:43,360
improve central corneal oxygenation ููู ูู ูุงู
229
00:20:43,360 --> 00:20:46,620
ุนูุฏู ุงูุญุงูุฉ ุงูุฃููู ุงู superficial panictate
230
00:20:46,620 --> 00:20:50,700
keratitis ูุฌููุง ุฅู ูู ุงู staining ููู ู
ูุฌูุฏุ ูู ุงู
231
00:20:50,700 --> 00:20:54,340
center ูุฃูุง ุจุฏู ุฃุฒูุฏ ุงู DK ุนูู T ูููุ ูู ุงู center
232
00:20:59,450 --> 00:21:04,870
Unlike ocular changes with other causes, ocular
233
00:21:04,870 --> 00:21:10,250
changes related to hypoxia and hypercapnia tend to
234
00:21:10,250 --> 00:21:14,410
affect only the cornea, and there are a few
235
00:21:14,410 --> 00:21:20,570
associated symptoms ุฏุงุฆู
ุงู ุงูุฃุนุฑุงุถ ุงููู ุจุชุณุจุจูุง
236
00:21:20,570 --> 00:21:25,210
ุงูhypercapnia ุฃู ุงูhypoxia ุจุชููู ู
ุชุนููุฉ ูู
237
00:21:25,210 --> 00:21:30,250
ุงููุฑููุฉ ูู ุจุนุถ ุงูุฃุญูุงู ุจุชููู ู
ุตุงุญุจุฉ ููุฃุฌุฒุงุก ุงููู
238
00:21:30,250 --> 00:21:35,630
ุญูุงููู ู
ููุ ุงููุฑููุฉ ุฒู ู
ุซูุงู ุฃูุด ูุง ุฑุบุฏุ ุฒู ู
ุซูุงู
239
00:21:35,630 --> 00:21:41,230
ุนูุฏูุง ุงู eyelid ุฃููู ูุตูุฑ ุนูุฏู eyelid disorders ุฃู
240
00:21:41,230 --> 00:21:45,090
ู
ุซูุงู ูุตูุฑ ุนูุฏู conjunctival staining ููุฐู ููููู
241
00:21:45,090 --> 00:21:51,370
ู
ุตุงุญุจุฉ ูู
ููุ ูููุฑููุฉ disorders ู ุจุงูุชุงูู ุงูู
ุฑูุถ
242
00:21:51,370 --> 00:21:55,110
ููุตูุฑ ุนูุฏู ุดููู ุฃูุซุฑ ูู ูุฐุง ุงูุฃู
ุฑ
243
00:21:59,300 --> 00:22:05,500
Stromal Edema ุทุจุนุงู ุจุฏุงูุฉ ุงูุงุณุชุฑูู
ุฉ ุฃู ุงู
244
00:22:05,500 --> 00:22:10,300
Substantia Epropria ูู ุจุชู
ุซู ุชุณุนูู ูู ุงูู
ุฆุฉ ุชูุฑูุจุงู
245
00:22:10,300 --> 00:22:17,470
ู
ู ุณู
ุงูุฉ ู
ููุ ุงููุฑููุฉarises within hours of the
246
00:22:17,470 --> 00:22:23,070
onset of hypoxiaุ ุงูุขู ุงูู hypoxia ูู
ุชูุชูู ููุท ูู
247
00:22:23,070 --> 00:22:27,610
ุงูุชุฃุซูุฑ ุนูู ุงูู corneal epitheliumุ ุจููู
ุง ุงู
ุชุฏ
248
00:22:27,610 --> 00:22:33,470
ุงูุฃู
ุฑ ููููุ ููุงุณุชุฑูู
ุฉุ ุฏุงุฆู
ุงู ูู
ุง ุชุณู
ุน ุฃู ูู ููุงู
249
00:22:33,470 --> 00:22:38,150
defect ู
ูุฌูุฏ ูู ุงูุงุณุชุฑูู
ุฉุ ูู ุงูุบุงูุจ ููููู ู
ุตุงุญุจ
250
00:22:38,150 --> 00:22:42,690
ูู infection ุฒู ุงูุงุณุชุฑุงู
ุฉ ุงู infiltration
251
00:22:46,690 --> 00:22:50,470
The degree being related to the severity of the
252
00:22:50,470 --> 00:22:56,310
hypoxia ููุฐุง ุจุงูุฃุณุงุณ ุจูุนุชู
ุฏ ุนูู ุญุฏุฉ ุงูููุจููุณูุฉ ูู
253
00:22:56,310 --> 00:23:01,710
ู
ุง ุฒุงุฏุช ุงูููุจููุณูุฉ ูู ู
ุง ูุงู ููุงู ุนุฑุถุฉ ุฃูุซุฑ ูุญุฏูุซ
254
00:23:01,710 --> 00:23:06,830
ู
ู ุงูููุจููุณูุฉ
255
00:23:06,830 --> 00:23:09,830
ุงูููุจููุณูุฉ related increase
256
00:23:11,810 --> 00:23:16,590
In anaerobic metabolism ุฏุงุฆู
ุงู ุฅููุง ุนูุงูุฉ ูู ุฒูุงุฏุฉ
257
00:23:16,590 --> 00:23:22,190
ู
ููุ ุนู
ููุฉ ุงููุฏู
ุ ุนูุฏูุง ุงู aerobic metabolism
258
00:23:22,190 --> 00:23:27,350
ุนู
ููุฉ ุงูุจูุงุกุ ุงู anaerobic metabolism ุนู
ููุฉ ุงููุฏู
259
00:23:28,670 --> 00:23:34,070
via the Emden-Meyerhof biochemical pathway of the
260
00:23:34,070 --> 00:23:40,170
epithelial cells ุทุจุนุงู ุนู
ููุฉ ุงููุฏู
ูู ู
ุตุงุญุจุฉ ููุคูุงุก
261
00:23:40,170 --> 00:23:46,370
ุงูุนุงูู
ูู Emden and Meyerhof ุงููู ุนู
ููุง ุชุฌุงุฑุจ ุทุจุนุงู
262
00:23:46,370 --> 00:23:50,490
ูุงูุช ูุฐู ุงูุชุฌุงุฑุจ ู
ู ุฎูุงู ุฃุฎุฐ ุนููุฉ ู
ู ุงู tiers
263
00:23:50,490 --> 00:23:54,630
ูุชุญููู ุงู protein ุงููู ู
ูุฌูุฏ ูู ุงู tier ูุจุนุฏ ุฐูู
264
00:23:54,630 --> 00:24:00,110
ุชุญููู ู
ุง ูู ู
ุตุงุญุจ ูู defect ุงููู ุญุฏุซ ูู ุงู corneal
265
00:24:00,110 --> 00:24:05,510
epithelium ู ุงู stroma accumulation ุฃููู ุตุงุฑ ูู
266
00:24:05,510 --> 00:24:10,590
ููุงู ุชุฑุงูู
of lactate ููุฃู
ูุงุญ ููู ูุฐุง ุงูุชุฑุงูู
ุญุฏุซุ
267
00:24:10,590 --> 00:24:16,770
in the stromaุงููููู ุทุจุนุงู ุตุงุฑ ููุงู ุชุฏูู of water
268
00:24:16,770 --> 00:24:22,290
into the stroma ูุญุฏุซ ุฃูุฏููู
ูุฉ ูุนูู ุจู
ุนูู ุฃููู ุฃูุด ุญุฏุซ
269
00:24:22,290 --> 00:24:28,390
ุญุงุฌุฉ ุญุงุฌุฉ ุจูุณู
ููุง ุงู swelling of
270
00:24:28,390 --> 00:24:37,530
the stroma ุฅุฐุง ุญุฏุซ ุงูุชูุงุฎ ูู
ููุ ููุงุณุชุฑูู
ุฉ
271
00:24:41,440 --> 00:24:48,370
corneal thickness ุฒูุงุฏุฉ ุงูุณู
ุงูุฉ ุทุจุนุงู ุฒูุงุฏุฉ ุงูุณู
ุงูุฉ
272
00:24:48,370 --> 00:24:54,770
ููุณ ู
ู ุงูุณูู ุนู
ููุฉ ุชูููู
ูุง ูููููููุงู ุทุจุนุงู ุงุญูุง ุจูุนุฑู
273
00:24:54,770 --> 00:25:00,030
ุฃู ููุงุณ ุณู
ุงูุฉ ุงููุฑููุฉ ู
ู
ูู ุฃู ูุชู
ู
ู ุฎูุงู ุฌูุงุฒ ุงู
274
00:25:00,030 --> 00:25:05,750
ุจุงูู
ูุชุฑ ูููู ุงูุขู ุฒูุงุฏุฉ ุณู
ุงูุฉ ุงููุฑููุฉ ูุชูุฌุฉ
275
00:25:05,750 --> 00:25:10,190
ุงุฑุชุฏุงุก ุงูุนุฏุณุฉ ุงููุงุตูุฉ ู
ุด ู
ู ุงูุณูู ุชูููู
ูุง ูููุ ูุฃูู
276
00:25:10,190 --> 00:25:16,570
ู
ู
ูู ู
ุซูุงู ูู ุงูุตุจุงุญ ูููู ุงูุณู
ุงูุฉ 500ุจุนุฏ ุงูุธูุฑ ูููู
277
00:25:16,570 --> 00:25:22,790
ู
ุซูุงู ุฃุฌูุ ู
ุซูุงู 450ุ ุจุนุฏ ุฐูู ูู ุงูููู
278
00:25:22,790 --> 00:25:27,650
ู
ู
ูู ูู
ุงู ุชูู ุฃูุซุฑุ ููู ู
ูุงุญุธูู ุฃูู variation ู
ู
279
00:25:27,650 --> 00:25:32,830
ุญูุซ ู
ููุ ุงู values ุฃู ุงู numbers ูู ูุชุฑุฉ ุฒู
ููุฉ
280
00:25:32,830 --> 00:25:38,470
ูุชุฎุชูู ุนู ุงููุชุฑุฉ ุงูุฒู
ููุฉ ุงูุซุงููุฉ ููุฐู ูู ุฏุงุฆู
ุงู ุงู
281
00:25:38,470 --> 00:25:42,250
complications ุงููู ู
ุตุงุญุจุฉ ูู
ููุ ููู soft contact
282
00:25:42,250 --> 00:25:47,490
lens ุงููู ู
ู ุงูุตุนุจ ุฃู ุงูู
ุฑูุถ ููุชุดููุง ูุนูู ู
ูู ู
ููุงุ
283
00:25:47,490 --> 00:25:51,450
ุงูุขู ูู ุจูุจุณ soft contact lens ูุนู
ู ุชูุช ู
ุฑุงุช ููุงุณ
284
00:25:51,450 --> 00:25:54,450
ููู corneal thicknessุ ููููู ูู
ุฑ ู
ุฌูุฏ
285
00:25:56,890 --> 00:26:01,330
ุฅุฐุง is not simple ููุณ ู
ู ุงูุณูู ุฃู ู
ู ุงูุจุณูุท to
286
00:26:01,330 --> 00:26:06,410
measure clinically ููุงุณูุง ุจุงูุนูุงุฏุฉ ุฃู ูู ุงูู center
287
00:26:06,410 --> 00:26:12,610
The edema response ุฏุงูู
ุง ุงุณุชุฌุงุจุฉ ุงูู edema begins
288
00:26:12,610 --> 00:26:17,610
ุชุจุฏุฃ within half an hour of lens insertion ุจุนุฏ
289
00:26:17,610 --> 00:26:22,540
ูุตู ุงูุณุงุนุฉ ุงูุฃููู ู
ู ุงุฑุชุฏุงุก ุงูุนุฏุณุฉ and generally
290
00:26:22,540 --> 00:26:27,900
peaks within three hours ูุจุชููู ุงููู
ุฉ ููุง ุจุนุฏ ูุฏูุดุ
291
00:26:27,900 --> 00:26:32,560
ุชูุช ุณุงุนุงุช in
292
00:26:32,560 --> 00:26:38,400
daily wear lenses typically ranges from one point
293
00:26:38,400 --> 00:26:43,100
five percent to five percent ุทุจุนูุง ููุง ุงูู
ูุตูุฏ ูููุง
294
00:26:43,100 --> 00:26:46,720
ุงูู conventional daily wear ุนุฏุณุงุช ุงููุจุณ ุงูููู
ู
295
00:26:46,720 --> 00:26:52,410
ุงูุชูููุฏู ุฅุฐุง ูุงูุช ุงููุณุจุฉ ูุฐู ู
ุง ุจูู ูุงุญุฏ ู ูุต ูุฎู
ุณุฉ
296
00:26:52,410 --> 00:26:58,150
ุจูููู normal ูููู ุจุฏู ุฃุณุฃู ุณุคุงู ุฅู ูุฐู ุงููุณุจุฉ ุทูู
297
00:26:58,150 --> 00:27:04,030
ุงูููู
ููุง ูู ูุชุฑุฉ ุฒู
ุงููุฉ ู
ุนููุฉุ ุทูู ุงูููู
ุทูู
298
00:27:04,030 --> 00:27:07,930
ุงูููู
ูุชุฎุชูู ูุจุชุงุนุฉ ุจุณ ูุงุฒู
ุชููู ุถู
ู ุงูู range ูุฐุง
299
00:27:07,930 --> 00:27:14,230
ูุนูู ุญุชู ูุณุงุนุงุช ุฒู ู
ุง ูุงู ุงูุดุบู ุฃูุง ุจููู ุจู
ุง ุฃู ูู
300
00:27:14,230 --> 00:27:20,070
ูุจุณ ูุนูู ู
ุฑุฉ ูุงุญุฏุฉ ูุฎูุงุต ุฅููู ูุฃ ุนุงุฏูุ ุจุชุถู
ู ูู
301
00:27:20,070 --> 00:27:25,770
ูุชุฑุฉ ู
ุนููุฉุ ูุฃ ู
ุด ูู ุงูููู
ุ ูุฅูู ูู
ุง ุจูุณุฃู ุตุจุงุญูุง
302
00:27:25,770 --> 00:27:28,570
ุฃุญูุงููุง ุฅููู
ุจุชููู ุนูุฏู ุฃุนูู ู
ู ุงููุณุจุฉ ูุฐูุ ูู
303
00:27:28,570 --> 00:27:31,050
ุทุจูุนู ุงูู thickness ุจูููู ุฃูุซุฑุ ูุนูู ุงูู school has
304
00:27:31,050 --> 00:27:39,750
to .. another answer ุงููุณุจุฉ ูุฐู ุจุชููู ุทุจูุนูุฉ ุฅุฐุง
305
00:27:39,750 --> 00:27:44,920
ูุงูุช ุทูู ุงูููู
ูุฃู ุฃูุชู ุดุงูููู ู
ุง ูู fixed number
306
00:27:44,920 --> 00:27:50,440
ูู ุฃููุ ุงููู ูู range ูุนูู ู
ู ูุงุญุฏ ู ูุต ูุฎู
ุณุฉ ูุนูู
307
00:27:50,440 --> 00:27:55,260
ู
ู
ูู ุฃูู ู
ุง ูุตุญู ู
ู ุงูููู
ุชููู ุฎู
ุณุฉ ุจุนุฏ ุฐูู ุจุชูู
308
00:27:55,260 --> 00:27:58,900
ูู ู
ุง ุงูุฅูุณุงู ุฑุงุญ ุนูู ุงูุนู
ู ุฃู ุนูู ุงูุฏุฑุงุณุฉ ุจุชูู
309
00:27:58,900 --> 00:28:02,380
ูุฐู ุงููุณุจุฉ ูููู ูุฐู ุงููุณุจุฉ ูู ุงูู conventional
310
00:28:02,380 --> 00:28:07,260
daily wear ุฅุฐุง ุฒุงุฏุช ุนู ุฎู
ุณุฉ ุฎูุงู ุงูููู
ููุง ุจูููู
311
00:28:07,260 --> 00:28:09,400
ูู ุฃููุ ุฃู
ุฑ ุงููู ูู pathology
312
00:28:12,530 --> 00:28:16,130
ุทุจุนูุง ูู ุญุงูุฉ ุนุฏุณุงุช ุงูู extended wear ุงููู ุจุชู
313
00:28:16,130 --> 00:28:20,170
ุงุฑุชุฏุงุฆูุง ูู
ุฏุฉ ุฃุณุจูุน ูุงู
ู ู ุจููุงู
ูููุง ุงููุณุจุฉ ูุฐู
314
00:28:20,170 --> 00:28:27,670
ุฃูุถูุง ูุชุฒูุฏ ูุชููู ุชูุฑูุจูุง ู
ู 10% ู 12% ูุฃูุถูุง ุฅุฐุง
315
00:28:27,670 --> 00:28:33,330
ูุงูุช ุงููุณุจุฉ ูุฐู ู
ู 10% ู 12% ุจูููู ุงูุฃู
ุฑ ุทุจูุนู
316
00:28:33,330 --> 00:28:38,550
ุฅุฐุง ุฒุงุฏุช ุนู ุฐูู ุจูููู ูู ููุงู ูุนูู ุฏุงุนู ููุชุฏุฎู ู
ู
317
00:28:38,550 --> 00:28:41,730
ูุจู ุงูู practitioner ุฃู ุงูู optometrist
318
00:28:45,100 --> 00:28:51,120
ู
ูุงุฑูุฉ ุงูุซูููุฉ ุงูููุจูุชูููุฉ ูู
ูู ุชุฃุซูุฑูุง ุฃูุถูุง ู
ู
319
00:28:51,120 --> 00:28:57,500
ููุน ู
ู ุงูููุจูุชูููุฉ ุฃู ู
ู ููุน ู
ู ุงูููุจูุชูููุฉ ุฃู ู
ู
320
00:28:57,500 --> 00:28:59,180
ููุน ู
ู ุงูููุจูุชูููุฉ ุฃู ู
ู ููุน ู
ู ุงูููุจูุชูููุฉ ุฃู ู
ู
321
00:29:02,530 --> 00:29:07,310
ุฏุงูู
ูุง ููู ููุงู ุนุงู
ููู ุฃุณุงุณููู ุจุฃุซุฑู ุนูู ู
ููุ ุนูู
322
00:29:07,310 --> 00:29:12,650
ุณู
ุงูุฉ ุงููุฑููุฉ ุงูุนุงู
ู ุงูุฃูู ูู ุชุฃุซูุฑ ุงูู reflex
323
00:29:12,650 --> 00:29:16,770
hypotonic tearing ุทุจุนูุง ุฅุญูุง ุนุงุฑููู ุงูู basic tear
324
00:29:16,770 --> 00:29:21,970
secretion ู
ู ุฃููุงุนู ุงูู reflex tearing ุตุญูุญุ ู
ุนูุงูุง
325
00:29:21,970 --> 00:29:27,360
hypotonic ุฅูุด ู
ุนูุงูุงุ ุฃููู ุจูููู ููุงู ุถุบุท ุงุณู
ูุฒู
326
00:29:27,360 --> 00:29:32,720
ูุนูู ุฏุงูู
ูุง ุงูู concentration ุงูุชุฑููุฒ ูู ุงูู stroma
327
00:29:32,720 --> 00:29:38,580
ููููู ู
ุฎุชูู ุนู ู
ููุ ุงูุฃุฌุฒุงุก ุงูุฃุฎุฑู ูู ุงููุฑููุฉ ููู
328
00:29:38,580 --> 00:29:47,340
ูุนููุ ููุชุฑุถ ู
ุซููุง ุนูุฏูุง ุงูู stroma ูุงู ูููุง ุงูู
329
00:29:47,340 --> 00:29:53,200
concentration ุนุดุฑุฉ
330
00:29:53,200 --> 00:30:00,550
ูู ุงูู
ูุฉ ุงูุงุจูุซูููุงู
ูุงูุฃุฌุฒุงุก ุงูุชุงููุฉ ู
ู ุงูู cornea
331
00:30:00,550 --> 00:30:07,310
ูุงูุช ุชูุงุชุฉ ูู ุงูู
ูุฉ ุฃู ุฃุฑุจุนุฉ ูู ุงูู
ูุฉ ูุนูู ุฃูู ูุฐุง
332
00:30:07,310 --> 00:30:12,030
ุจูุนู
ู ุฃููุ tearing hypotonic ูุนูู ุจูููู ุงูุชู
ุฑูุฒ ุฃู
333
00:30:12,030 --> 00:30:17,010
ุงูุชุฑููุฒ ูู ุงูู stroma ุฃุนูู ู
ู ุจุงูู ุงูุฃุฌุฒุงุก ูุจูุนู
ู
334
00:30:17,010 --> 00:30:22,890
ุญุงุฌุฉ ุจูุณู
ููุง reflex hypotonic tearing ูุงุถุญุฉุ
335
00:30:24,290 --> 00:30:29,150
or by a physical thinning of the stroma ุงูู long
336
00:30:29,150 --> 00:30:35,950
term wear ุงูุขู ุจุนุถ ุงููุงุณ ุจูููู ู
ุฎุตุต ุฅูู ุฅูู ููุจุณ
337
00:30:35,950 --> 00:30:41,450
ุงูุนุฏุณุฉ ุงููุงุตูุฉ ูู
ุฏุฉ ุนุดุฑ ุณุงุนุงุช ุจุฑูุญ ุจูุจุณูุง ุฎู
ุณ ุนุดุฑ
338
00:30:41,450 --> 00:30:47,030
ุณุงุนุงุช ุฅุฐุง ุตุงุฑ ุนูุฏู ุฅูุดุ long term wear ูุฐุง ุฅูุด ููู
339
00:30:47,030 --> 00:30:51,690
ููุนู
ู thinning ููุงุณุชุฑูู
ุฉุ ููููู ู
ู ุณู
ุงูุฉ ู
ููุ
340
00:30:51,690 --> 00:30:53,770
ุงูุงุณุชุฑูู
ุฉ ู
ุน ุงูููุช
341
00:30:58,120 --> 00:31:03,300
Also there is marked individual variability in the
342
00:31:03,300 --> 00:31:08,740
degree of corneal swelling response ุจุนุถ ุงูุฃุญูุงู
343
00:31:08,740 --> 00:31:14,460
ุจูููู ูุฐุง ุงูููุงู
ุบูุฑ ู
ุนู
ู
ุนูู ูู ุงููุงุณุ ููู ูุนููุ
344
00:31:14,860 --> 00:31:20,140
ุงูุขู ู
ุซููุง ููุฑ ุงุฑุชุฏุช ุนุฏุณุฉ conventional daily wear
345
00:31:20,140 --> 00:31:24,600
ุงูู parameters ู
ุนูู ู
ู ุญูุซ ุงูู base curve ุงูู power
346
00:31:24,600 --> 00:31:29,880
ุงูู diameter ุงูู water content ุงูู thickness ูู ูุฐุง
347
00:31:29,880 --> 00:31:35,080
ู
ุดุงุจู ูู
ููุ ูุนุฏุณุฉ ุงุฑุชุฏุชูุง ุฎุฏูุฌุฉ ูู ููุณ ุฅูุด ุงูู
348
00:31:35,080 --> 00:31:39,940
parameters ุงูุขู ูุฏ ูููู ุนูุฏูุง ุงูู stroma ุงููุฏูู
ุฉ
349
00:31:39,940 --> 00:31:45,660
ู
ุฎุชููุฉ ุนู ู
ููุ ุนู ุงููู ูู ุฎุฏูุฌุฉ ููู ุดุฎุต ุจูููู ู
ุฎุชูู
350
00:31:45,660 --> 00:31:51,140
ุนู ุงูุขุฎุฑ ูู ุงุณุชุฌุงุจุชู ูู
ููุ ููุชุฃุซูุฑุงุช ุงูุฎุงุฑุฌูุฉ ุงููู
351
00:31:51,140 --> 00:31:56,200
ุจุชุทุฑู ู
ู ุฎูุงู ุงูุนุฏุณุฉ ุงููุงุตูุฉ ูุฐูู ุฅุญูุง ูููุง there
352
00:31:56,200 --> 00:32:00,220
is marked individual ูุนูู ููููู ูุฐุง ุงูุฃู
ุฑ ูุฑุฏู
353
00:32:00,220 --> 00:32:06,360
variability ุงุฎุชูุงู ูู ุฏุฑุฌุฉ ุฃููุ ุงูุชูุงุฎ ุฃู ุงูุงุณุชุฌุงุจุฉ
354
00:32:06,360 --> 00:32:12,820
ูุงูุชูุงุฎ ู
ู ุงูู cornea corneal
355
00:32:12,820 --> 00:32:17,580
distortion ุทุจุนูุง ุงูู corneal distortion ุฏุงูู
ูุง ุจุชููู
356
00:32:17,580 --> 00:32:23,330
ู
ุตุงุญุจุฉ ูู
ููุ ููู RGP ุงูู RGP ุฃู ุงูู hard contact
357
00:32:23,330 --> 00:32:27,910
lenses ู
ู ุงูู advantages ููู soft contact lens ุฃููู
358
00:32:27,910 --> 00:32:32,990
ุจูููู ุบูุฑ ุดุงุฆุน ุฃู very rarely ูุชูุฌุฉ ุฃููู ุฅูุด ุงูู
359
00:32:32,990 --> 00:32:37,010
soft contact lens ุฏุงูู
ูุง ุจูุณุจุจ minimal central
360
00:32:37,010 --> 00:32:38,630
corneal distortion
361
00:32:41,500 --> 00:32:46,780
ุฃุณุจุงุจูุง number one a result of poor RGP lens
362
00:32:46,780 --> 00:32:52,020
fitting ูุงูุช ุงูุนุฏุณุฉ ู
ุซููุง tight ุฃู ูุงูุช ุงูุนุฏุณุฉ flat
363
00:32:52,020 --> 00:32:57,400
ู
ู
ูู ูุณุจุจ ุนูุฏ ุงูู
ุฑูุถ corneal distortion or wear of
364
00:32:57,400 --> 00:33:02,900
low Dk ุนูู t ุฃู ุฏุงูู
ูุง ุจูุจุณ ุนุฏุณุงุช ูููุง Dk ุนูู t
365
00:33:02,900 --> 00:33:08,460
very low ุฅูุด ู
ุนูุงูุงุ ูุนูู ุญูุงุชูุง ู
ุฏุฉ ุญูุงุชูุง ุทูููุฉ
366
00:33:08,460 --> 00:33:09,180
ุงูุนุฏุณุฉ
367
00:33:19,520 --> 00:33:25,300
ุฃู ุจูุจุณ ุนุฏุณุงุช ูุงุตูุฉ ููุท ู
ุตููุนุฉ ู
ู ู
ุงุฏุฉ ุงูู
368
00:33:25,300 --> 00:33:28,600
polymethyl methacrylate ุงููู ูู ุชุนุชุจุฑ ุงูุฌูู ุงูุฃูู
369
00:33:28,600 --> 00:33:32,460
ู
ู ุงูุนุฏุณุงุช ุทุจุนูุง ูุฃููุฏ ูุฐุง ููุณุจุจ ุฅูุดุ Cornial
370
00:33:32,460 --> 00:33:36,760
distortion ูุฐูู ุงูู researchers ุงูุจุงุญุซูู ุนู
ููุง ุนูู
371
00:33:36,760 --> 00:33:40,740
ุฅุถุงูุฉ ู
ููุ ู
ุงุฏุฉ ุงูู silicon ุนุดุงู ุชุฒูุฏ ู
ู ุงูู
372
00:33:40,740 --> 00:33:44,920
wetability ุงูู
ุชุงูุฉ ูู ุงูุฌูู ุงูุซุงูู ู
ู ูุฐุง ุงูููุน ู
ู
373
00:33:44,920 --> 00:33:50,920
ุงูุนุฏุณุงุช is an uncommon complication of hydrogel
374
00:33:50,920 --> 00:33:56,220
lens wear ุทุจุนูุง ูู ุบูุฑ ู
ุง ูุชููู ุดุงุฆุนุฉ ู
ุน ุนุฏุณุงุช ุฃููุ
375
00:33:56,220 --> 00:33:59,040
ุงูู conventional daily wear soft contact lenses
376
00:33:59,040 --> 00:34:03,740
ุงูุณุจุจ ูู ุฐูู minimal central corneal distortion
377
00:34:07,210 --> 00:34:13,250
Such distortion is known as spectacle flare or
378
00:34:13,250 --> 00:34:18,450
corneal warpage and is manifested as a change in
379
00:34:18,450 --> 00:34:22,890
the spectacle refraction and central corneal
380
00:34:22,890 --> 00:34:28,250
curvature ูุฐุง ุงูู corneal distortion ุฎุทูุฑุชู ุฃููู
381
00:34:28,250 --> 00:34:32,590
ุจูุนู
ู ุญุงุฌุฉ ุจูุณู
ููุง ุงูู spectacle flare ุดู ู
ุนูุงูุงุ
382
00:34:33,530 --> 00:34:37,450
ุฃููู ููููู ููู ุงุฎุชูุงู ููุฑุคูุฉ ู
ุง ุจูู ุงุฑุชุฏุงุก ุงูุนุฏุณุฉ
383
00:34:37,450 --> 00:34:42,310
ุงููุงุตูุฉ ูุงููุถุงุฑุฉ ูุทุจุนูุง ูุฐุง ุจูุคุฏู ูุฅูุดุ ูููุฑููุฉ
384
00:34:42,310 --> 00:34:46,190
ุงููุฏูู
ุฉ ูุฃููู ุฏุงูู
ูุง ุงููุฑููุฉ ุงููุฏูู
ุฉ ูู ุงูุนุฏุณุงุช ุงูู
385
00:34:46,190 --> 00:34:51,630
hard contact lens ุฃูุซุฑ ู
ู ุงูู soft contact lenses ู
386
00:34:51,630 --> 00:34:55,830
ุฃูุถูุง ุจูุนู
ู ุนูู ุชุบููุฑ ูู ุฅูุดุ ูู ุชุญุฏุจ ุงููุฑููุฉ ุงูู
387
00:34:55,830 --> 00:35:01,650
corneal curvature power ูุชููู ุฅู ุดุงุก ุงููู ููุงุณุชุฑุงุญุฉ
388
00:35:01,650 --> 00:35:05,790
ุงูุงุณุชุฑุงุญุฉ ูู ุงูู
ุญุงุถุฑุฉ ุงููุงุฏู
ุฉ ุจููู
ู ุฅู ุดุงุก ุงููู
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