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1
00:00:00,000 --> 00:00:08,880
ุจุญุจ ุฅู†ู‡ ุงู„ูˆุงุญุฏ ู…ู†ู†ุง ูŠูƒูˆู† ุจู‡ู†ู‡ ุตูˆุฑุฉ ูƒุงู…ู„ุฉ ูˆู‡ูŠูƒ

2
00:00:08,880 --> 00:00:13,120
ูŠุญุงูˆู„ ูŠูู‡ู… ุฅุญู†ุง ุจู†ุญุงูˆู„ ุดูˆ ู†ู‚ูˆู„ ุฃูˆ ุดูˆ ู†ุฏุฑุณ ุฃูˆ ุดูˆ

3
00:00:13,120 --> 00:00:16,980
ู†ุชุนุงู…ู„ ุงู„ุขู†

4
00:00:16,980 --> 00:00:23,480
ุงู„ูˆุฑุงุซุฉ ุจุชุนุชู…ุฏ ุนู„ู‰ ุฅู† ุงู„ู€DNA ุงู„ู„ูŠ ุงุชูƒู„ู…ู†ุง ุนู†ู‡ ุงู„ู„ูŠ

5
00:00:23,480 --> 00:00:29,450
ู‡ูˆ ุฃุณุงุณ ููŠ ุชูƒูˆู† ุงู„ุจุฑูˆุชูŠู†ูˆู‡ูˆ ุงู„ู…ุณุฆูˆู„ ุนู† ุชูƒูˆูŠู†

6
00:00:29,450 --> 00:00:38,290
ุงู„ุจุฑูˆุชูŠู†ุงุช ูˆู‡ูˆ ู…ูˆุฌูˆุฏ ุจุดูƒู„ ู…ุชุณุงูˆูŠ ููŠ ุงู„ุบุงู„ุจ ูŠุนู†ูŠ ูƒู„

7
00:00:38,290 --> 00:00:45,230
ุงู„ุฎู„ุงูŠุงุŒ ู…ุง ุนุฏุง ุงู„ุฎู„ุงูŠุง ุงู„ุฌู†ุณูŠุฉ ูˆูŠูƒูˆู† ุงู„ุฎู„ุงูŠุง

8
00:00:45,230 --> 00:00:52,350
ุจุชู‚ูˆู… ุจุทุฑูŠู‚ุฉ ุฏู‚ูŠู‚ุฉ ุฌุฏุงู‹ ุจุนู…ู„ูŠุฉ ุชูƒุฑุงุฑ ุงู„ู€DNA ุญูŠุซ

9
00:00:52,350 --> 00:00:57,670
ุฅู†ู‡ ุฏุงูŠู…ุงู‹ุงู„ู€ ยซDNAยป ุชุจุน ูƒู„ ุงู„ุฎู„ุงูŠุง ุงู„ุฃุตู„ูŠ ูŠู‚ูˆู„

10
00:00:57,670 --> 00:01:07,450
ยซูƒู„ู‡ ู…ุชุดุงุจู‡ยป ุจุนุฏูŠู† ูŠุนู†ูŠ ุงุชูƒู„ู…ู†ุง ุนู† ุฅู†ู‡ ุนู†ุฏู†ุง ูŠุนู†ูŠ

11
00:01:07,450 --> 00:01:12,390
ู‡ูŠูƒ ูƒู…ุจุฏุฃ ุจุฏูŠ ุงู„ูˆุงุญุฏ ู‡ูŠูƒ ูŠุชุฐูƒุฑ ูˆุจุนุฏูŠู† ู‚ุถูŠุฉ ุฅู†ู‡

12
00:01:12,390 --> 00:01:18,290
ุงุญู†ุง ุชู‚ุฑูŠุจุงู‹ ูƒุฃู†ูˆุงุน ู…ุฑุงุฏ ูˆุญู„ุงู„ ุจุชู…ู†ูŠ ููŠ ุงู„ูˆุฑุงุซุฉ

13
00:01:18,290 --> 00:01:24,990
ู†ุชูƒู„ู… ุนู„ู‰ ุซู„ุงุซ ุฃู†ูˆุงุนููŠ ุญุงู„ุงุช ุฃูˆ ุฃู…ุฑุงุถ ู†ุชูŠุฌุฉ ุชุฎู„ู†ูŠ

14
00:01:24,990 --> 00:01:29,090
ููŠ ุงู„ูƒุฑูˆู…ูˆุฒูˆู… ูƒู„ู‡ ูุงู„ู€ Chromosomal Diseases ู‡ุฏูˆู„

15
00:01:29,090 --> 00:01:33,370
ุนุงุฏุฉ ุงูƒุจุงุฑ ูƒุซูŠุฑ ูˆุงู„ู„ูŠ ู‡ู… ู…ุดุงูƒู„ ูƒุซูŠุฑุฉ ุฒูŠ ุงู„ู€ Down

16
00:01:33,370 --> 00:01:39,910
Syndrome ูˆููŠ Mendelian Diseases ุงู„ู„ูŠ ู‡ูŠ ุจูŠู‚ูˆู„ ูู‚ุท

17
00:01:39,910 --> 00:01:44,890
Single Gene ู‡ูˆ ุงู„ู…ุณุคูˆู„ ุนู† ุงู„ู…ุฑุถ ูˆููŠ ุนู„ุงู‚ุฉ ุจูŠู†ู‡ู…

18
00:01:44,890 --> 00:01:49,910
ูˆููŠ ู„ู‡ุง ุฃู…ุซู„ุฉูˆุงู„ุดุบู„ ุงู„ุซุงู„ุซ ุงู„ู„ูŠ ู‡ูŠ ุงู„ุบุงู„ุจูŠู† ุฃุบู…ุถ

19
00:01:49,910 --> 00:01:53,170
ู…ู† ูƒุซูŠุฑ ู…ู† ุงู„ุฃู…ุฑุงุถ ุฒูŠ ุงู„ุถุบุท ูˆุงู„ุณูƒุฑูŠ ูˆุงู„ุฑุจูˆ

20
00:01:53,170 --> 00:02:00,050
ูˆุงู„ุฃู…ุฑุงุถ ุงู„ูƒุซูŠุฑุฉ ููŠ ุญุงู„ุงุช ุจูŠูƒูˆู† ุฃู†ู‡ ุจูŠุดุชุฑูƒ ุนุฏุฏ

21
00:02:00,050 --> 00:02:04,430
ูƒุจูŠุฑ ู…ู† ุงู„ุฌูŠู†ุงุช ููŠู‡ุง ุจุณ ู…ุด chromosome ุนุฏุฏ ูƒุจูŠุฑ ู…ู†

22
00:02:04,430 --> 00:02:14,470
ุงู„ุฌูŠู†ุงุช ุงู„ู†ูˆุน ุงู„ุซุงู„ุซ ู‡ุฐุง ู…ุฑุชุจุท ุจู‚ุงู„ูŠุฉ ุงู„ุชุญูƒู… ููŠ

23
00:02:14,470 --> 00:02:21,680
ุงู„ู€Expression ู„ู„ู€GeneูŠุนู†ูŠ ุจุฏูƒ ุชูู‡ู… ุฅู†ูƒ ุฃู†ุช ุงู„ุฌูŠู†

24
00:02:21,680 --> 00:02:26,920
ุงู„ูˆุงุญุฏ ู…ุด ุดุบุงู„ ููŠ ูƒู„ ุงู„ุฎู„ุงูŠุง ุงู„ุฎู„ูŠุฉ ุงู„ู„ูŠ ุจุชุญุชุงุฌ

25
00:02:26,920 --> 00:02:32,120
ู‡ุฐุง ุงู„ุฌูŠู† ูŠุดุชุบู„ ู‡ูŠ ุงู„ุฎู„ูŠุฉ ุงู„ู„ูŠ ุฑุงุญ ุชุดุบู„ู‡ ูˆุฃุญูŠุงู†ู‹ุง

26
00:02:32,120 --> 00:02:41,210
ูƒุซูŠุฑุฉ ูŠุนู†ูŠ ู…ู† ุงู„ู€22ุŒ 23 ุฃู„ู ุฌูŠู† ู…ูˆุฌูˆุฏูŠู†ุจูƒูˆู† ุนุฏุฏ

27
00:02:41,210 --> 00:02:46,310
ู‚ู„ูŠู„ ู…ู† ุงู„ุฌูŠู†ุงุช ุงู„ู„ูŠโ€ฆ ูŠุนู†ูŠ ู†ุณุจุฉ ู‚ู„ูŠู„ุฉ ู…ู† ุงู„ุฌูŠู†ุงุช

28
00:02:46,310 --> 00:02:53,570
ุจุชุชู… ุชุดุบูŠู„ู‡ุงุŒ ูโ€ฆ ุขู„ูŠุงุช ุงู„ุชุญูƒู… ููŠ ู…ูŠู† ู…ู† ุงู„ุฌูŠู†ุงุช

29
00:02:53,570 --> 00:02:57,950
ูŠุดุชุบู„ ูˆู…ูŠู† ู…ุง ูŠุดุชุบู„ุด ูˆุฅู…ุชู‰ ูŠุดุชุบู„ ูˆุฅู…ุชู‰ ู…ุง ูŠุดุชุบู„ุดุŒ

30
00:02:57,950 --> 00:03:01,910
ู‡ุฐู‡ ุจุฏู†ุง ู†ุณู…ูŠู‡ุง Epigenetic MechanismsุŒ ุงู„ู„ูŠ ู‡ูŠ

31
00:03:01,910 --> 00:03:09,740
ุขู„ูŠุงุช ุงู„ุชุญูƒู… ููŠ ุงู„ุชู†ุดูŠุท ุฃูˆ ุชู†ูˆูŠู… ุงู„ุฌูŠู†ุงุชูˆุงู„ูุฑูˆู‚ุงุช

32
00:03:09,740 --> 00:03:15,320
ููŠู‡ุง ูู‡ุฐู‡ ุงู„ุธูˆุงู‡ุฑ ุงู„ู„ูŠ ุจู†ุชูƒู„ู… ุนู†ู‡ุง ูƒู€ Epigenetic

33
00:03:15,320 --> 00:03:22,800
ุนู…ู„ูŠุฉ ุงู„ุชุฎู„ู‚ ูƒูŠู ุจุชุชู… ุนู…ู„ูŠุงุช ู…ุชุนุฏุฏุฉ ูˆูƒุซูŠุฑุฉ ูˆู‡ูŠ

34
00:03:22,800 --> 00:03:27,300
ูŠุนู†ูŠ ูŠุนู†ูŠ

35
00:03:27,300 --> 00:03:33,520
ู‡ูŠ ุจุชู‚ูˆู… ุงู„ุขู† ูŠุนู†ูŠ ุจูŠุญุงูˆู„ูˆุง ุฃู†ู‡ ู…ู† ุฎู„ุงู„ู‡ุง ูŠุนู†ูŠ

36
00:03:33,520 --> 00:03:39,620
ูŠูู‡ู…ูˆุง ูƒุซูŠุฑ ู…ู† ุงู„ุฃู…ุฑุงุถุŒ ุจุนุถ ุงู„ุฃู…ุฑุงุถูˆุจูŠู„ุงุญุธูˆุง ุฅู†ู‡

37
00:03:39,620 --> 00:03:45,920
ู…ู…ูƒู† ู†ูู‡ู… ู…ู†ู‡ุง ุฃูˆ ู…ู† ุฎู„ุงู„ู‡ุง ุฃูŠุถู‹ุง ู„ู„ุขู† ู…ุง ู†ุฌุญูˆุด ุจุณ

38
00:03:45,920 --> 00:03:53,480
ุจุชุฃู…ู„ูˆุง ุฅู†ู‡ ูŠูƒูˆู†ูˆุง ุฃุฏูˆูŠ ุฃูˆ ุทุฑุงุฆู‚ ุชุนุฏูŠู„ ุงู„ู…ุฑุถ ู…ู†

39
00:03:53,480 --> 00:04:00,560
ุฎู„ุงู„ ุงู„ุชุฏุฎู„ ุจุทุฑูŠู‚ุฉ ู…ููŠุฏุฉ ุฃูˆ ุถุฏ ุงู„ู…ุฑุถ ููŠ ุฅู†ู‡ ุดูˆ

40
00:04:00,560 --> 00:04:04,830
ุงู„ู„ูŠ ุจุฏู†ุง ูŠุนูŠุด ุชุดุชุบู„ ูˆุดูˆ ุงู„ู„ูŠ ุจุฏู†ุง ูŠุนูŠุด ู…ุดุชุบู„ุดุงู„ุขู†

41
00:04:04,830 --> 00:04:11,050
ุงู„ู…ุญุงุถุฑุฉ ุงู„ูุงุตู„ุฉ ุงู„ุซุงู„ุซ ู‡ูŠ ุจุชุชูƒู„ู… ุนู† ุชุฑูƒูŠุจ

42
00:04:11,050 --> 00:04:17,690
ุงู„ูƒุฑู…ูˆุฒูˆู…ุงุช ูˆุงู„ุฌูŠู†ุงุช ูˆูƒูŠู ู‡ูŠ ู…ูˆุฌูˆุฏุฉ ุนู„ู‰ ุงู„ู€DNA ููŠ

43
00:04:17,690 --> 00:04:24,170
ูˆุณุท ุงู„ุฎู„ูŠุฉ ุงู„ู…ุญุงุถุฑุฉ ุงู„ู„ูŠ ุจุนุฏู‡ุงุŒ ุงู„ุซุงู†ูŠุฉุŒ ุฑุงุญ ู†ุชูƒู„ู…

44
00:04:24,170 --> 00:04:29,430
ูƒูŠู ุฅุญู†ุง ู…ุชู†ูˆุนูŠู†ุŒ ุดูˆ ุงู„ุงุฎุชู„ุงูุงุช ุงู„ู„ูŠ ู…ูˆุฌูˆุฏุฉ ุจูŠู†

45
00:04:29,430 --> 00:04:38,020
ุงู„ุจุดุฑ ุนู…ูˆู…ุงุŒ ูˆุจุงู„ุชุงู„ูŠ ูŠุนู†ูŠ ู…ุญุงูˆู„ุฉ ุชุดุฑุญุงู„ูˆุฌูˆุฏ ุชูุงูˆุช

46
00:04:38,020 --> 00:04:44,460
ุจูŠู† ุงู„ุจุดุฑ ุฅู†ู‡ ู…ุด ุจุณ ุงู„ุชูุงูˆุช ู‡ูˆ ู†ุชูŠุฌุฉ ุงุฎุชู„ุงู ุงู„ู€

47
00:04:44,460 --> 00:04:49,620
DNA ู†ูุณู‡ ุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ุฌูŠู†ุงุช ู†ูุณู‡ุง ุงู„ู€ Epigenetic

48
00:04:49,620 --> 00:04:54,260
Mechanisms ุฏูˆู„ุฉ ูƒู…ุงู† ุงู„ู„ูŠ ู„ู‡ู… ุฏูˆุฑ ููŠ ุฅู†ู‡ ู‡ุฐุง

49
00:04:54,260 --> 00:04:59,000
ุงู„ุฅู†ุณุงู† ูŠุทู„ุน ุดูˆูŠู‡ ู…ุฎุชู„ู ุนู† ุงู„ุฅู†ุณุงู†ูู‡ู†ุง ู…ุซู„ู‹ุง ู…ุซุงู„

50
00:04:59,000 --> 00:05:04,480
ุฅู†ู‡ ุฃู†ุง ุงู„ู€โ€ฆ ุจุงู„ู€Karyotype ุทุจุนู‹ุง ุฅุฐุง ุญุฏ ู…ุด ูุงู‡ู…

51
00:05:04,480 --> 00:05:11,340
ุฅูŠุด ูŠูˆู‚ู ูŠุนู†ูŠ ุฏูƒุชูˆุฑ ุฃุญู…ุฏ ุฃุทู„ุจ ู…ู† ุฃูŠ ุฅู†ุณุงู† ุนู†ุฏู‡ ุฃู†ุง

52
00:05:11,340 --> 00:05:16,200
ู…ุด ุญุงุทุท ุงู„ู€Chat ุฃูˆ ู…ุด ู…ุจูŠู† ู…ุนุงู‡ ุงู„ู€Chat ุฅุฐุง ุจุฏูƒู…

53
00:05:16,200 --> 00:05:21,180
ุฃุญุทู‡ Show Video Grid ูˆู„ุง ูƒุฏู‡ ุฅุฐุง ุญุฏ ุจูŠุญุจ ูŠุณุฃู„ ุฃูˆ

54
00:05:21,180 --> 00:05:26,590
ุนู„ู‰ ุงู„ู€Facebook ุฃูˆ ุงู„ู€WhatsApp ุจูŠุณุฃู„ ุณุคุงู„ุจุฑุถู‡

55
00:05:26,590 --> 00:05:30,850
ุจูŠุตูŠุฑ ูุฅุฐุง

56
00:05:30,850 --> 00:05:38,130
ุฃุฎุฏู†ุง ุงู„ุขู† ูŠุนู†ูŠ ู„ู…ุง ุฅุญู†ุง ู†ูŠุฌูŠ ู†ู‚ุฑุฃ ุงู„ู€ ุจุฏู‚ุฉ ุฃูƒุซุฑ

57
00:05:38,130 --> 00:05:44,550
ุชุฑูƒูŠุจ ุงู„ู€ Gene ูˆุชุฑูƒูŠุจ ุงู„ู€ DNA ุฃูˆ ุงู„ู€ Chromosome

58
00:05:44,550 --> 00:05:50,530
ุงู„ู„ูŠ ู‡ูˆ ุงู„ูƒุชู„ุฉ ุงู„ูƒุจูŠุฑุฉ ุจู„ุงู‚ูŠ ุฅู† ุฃู†ุง ู„ู…ุง ุฃุฌูŠ ุฃุดูˆู

59
00:05:50,530 --> 00:05:55,630
Chromosome ุฒูŠ ู‡ู†ุง Chromosome 11ูƒู†ุง ู†ุญูƒูŠ ุฅู†ู‡ ููŠู‡

60
00:05:55,630 --> 00:06:00,470
Centromere ุจุงู„ู†ุตุฑ ุนุดุงู† ูŠุนุฑู ูŠุชูˆุฌู‡ ู„ู„ุฌู‡ุชูŠู†

61
00:06:00,470 --> 00:06:05,010
ุงู„ู…ุชุถุงุฏุงุช ููŠ ุงู†ู‚ุณุงู… ุงู„ุฎู„ูŠุฉ ููŠ ุฅุดูŠ ุฒูŠ ุงู„ู€Telomere

62
00:06:05,010 --> 00:06:09,810
ุนุดุงู† ุงู„ู„ูŠ ู‡ูˆ ุงู„ุฅุดูŠ ุงู„ู…ุทุฑู ุงู„ู„ูŠ ุขุฎุฑุชู‡ ู…ุณุจุญุฉ ุนุดุงู†

63
00:06:09,810 --> 00:06:16,570
ูŠุชุญูƒู… ููŠ ุนุฏุฏ ู…ุฑุงุช ุงู†ู‚ุณุงู… ุงู„ุฎู„ุงูŠุง ูุฅุฐุง ุจู†ุงุฎุฏ ุฅู†ู‡

64
00:06:16,570 --> 00:06:22,050
ุฃู†ุง ุฌุจุช ููŠ ู„ุญุธุฉ ู…ุนูŠู†ุฉ ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€Chromosome 11

65
00:06:23,210 --> 00:06:28,890
ุงู„ู…ู†ุทู‚ุฉ ุงู„ู„ูŠ ู‡ูŠ ุงู„ุฎุงู…ุณ

66
00:06:28,890 --> 00:06:34,070
ูˆูุงุตู„ ุงู„ุฎู…ุณุชุงุดุฑ ุฅู„ู‰ ุงู„ุฎุงู…ุณ ูˆูุงุตู„ ุงู„ุฎู…ุณ ูˆุซู„ุงุซูŠู†

67
00:06:34,070 --> 00:06:40,070
ูŠุนู†ูŠ ู‡ู†ุง ู‡ุงูŠ ุงู„ู‚ุทุนุฉ ุงู„ุตุบูŠุฑุฉ ุงู„ู„ูŠ ุจูŠุณู…ูˆู‡ุง ุงู„ู€P ุงู„ู„ูŠ

68
00:06:40,070 --> 00:06:46,270
ู‡ูŠ P ู„ู„ุชุญุช ูˆุจุนุฏูŠู† ุงู„ู€Q ุงู„ุทูˆูŠู„ ู„ู„ุชุญุช ุนุงุฏุฉู‹ ุจู†ุจุฏุฃ ู…ู†

69
00:06:46,270 --> 00:06:52,780
ููˆู‚ ูˆู†ู…ุดูŠ ููŠู‡ู… ู„ู„ุชุญุชูุจู†ู„ุงุญุธ ุฅู†ู‡ ููŠ ู…ู†ุงุทู‚ ููŠู‡ุง ูƒุซูŠุฑ

70
00:06:52,780 --> 00:06:58,760
ุฌูŠู†ุงุช ูˆููŠู‡ุง ุทุฑูŠู‚ุฉ ุฅู† ุงู„ูˆุงุญุฏ ูŠุนุฑู ุฅู† ู‡ุฐุง ุนุจุงุฑุฉ ุนู†

71
00:06:58,760 --> 00:07:07,420
ุฌูŠู† ูŠุนู†ูŠ ู‚ุทุนุฉ ุงู„ู€ DNA ูŠุชู… ู‚ุฑุงุกุชู‡ุง ูŠู‚ุฏุฑ ุฒูŠ ู…ุง ุญูƒูŠุช

72
00:07:07,420 --> 00:07:12,700
ุงู„ู…ุฑุฉ ุงู„ู„ูŠ ูุงุชุช ุฅู†ู‡ ุญูˆุงู„ูŠ 4% ูู‚ุท ู…ู† ุงู„ู€ DNA ููŠ

73
00:07:12,700 --> 00:07:19,900
ุงู„ุฅู†ุณุงู† ุนุจุงุฑุฉ ุนู† coding DNA ูŠุนู†ูŠุฅุจุงุฑุฉ ุนู† ุฅุดูŠ ุฑุงุญ

74
00:07:19,900 --> 00:07:25,160
ูŠุชู… ุงุณุชูุงุฏุฉ ู…ู†ู‡ ููŠ ุนู…ู„ ุงู„ุจุฑูˆุชูŠู† ู„ุงุญู‚ู‹ุง ูˆุงู„ุบุงู„ุจูŠุฉ

75
00:07:25,160 --> 00:07:30,480
ุงู„ุนุธู…ู‰ ู…ู† ุงู„ู€DNA ุฅุจุงุฑุฉ ุนู† ุงู„ู€Non-Coding DNA ูŠุนู†ูŠ

76
00:07:30,480 --> 00:07:38,620
ุจุณ ุชูƒู…ุงู„ุฉ ูˆุญุดูˆุฉ ูˆุฅุดูŠ ู…ูˆุฌูˆุฏ ุจุงู„ู†ุตูŠุนู†ูŠ ูŠุธู† ุฅู† ู‡ุฐุง

77
00:07:38,620 --> 00:07:43,100
ุจูŠุณุงุนุฏ ู„ุฃู†ู‡ ุญุชู‰ ู„ูˆ ุตุงุฑ ุฎู„ู„ ููŠ ุงู„ู€ DNA ุฅู†ู‡ ูŠุตูŠุฑ

78
00:07:43,100 --> 00:07:48,300
ุงุญุชู…ุงู„ูŠุฉ ุฃูƒุจุฑ ุฅู† ูŠูƒูˆู† ุงู„ุฎู„ู„ ููŠ ู…ู†ุทู‚ุฉ ุบูŠุฑ ุถุงุฑุฉ ุฃูˆ

79
00:07:48,300 --> 00:07:54,680
ุบูŠุฑ ู…ุณุจุจุฉ ู„ู…ุฑุถ ูŠุนู†ูŠ ู‡ูŠูƒ ูŠุธู† ุงู„ุขู† ูู„ูˆ ุฌูŠู†ุง ู†ุงุฎุฏ ู‡ุฐู‡

80
00:07:54,680 --> 00:07:58,300
ุงู„ู‚ุทุนุฉ ุงู„ุตุบูŠุฑุฉ ุงู„ู„ูŠ ู‡ูŠ ู…ูˆุฌูˆุฏุฉ ู‡ู†ุง ุจุงู„ู€ Karyotype

81
00:07:58,300 --> 00:08:03,900
ุจุดูƒู„ ุงู„ู€ Karyotype ู„ู€ Chromosome 11 ูˆุฃู†ุง ุฃูƒุจุฑู‡ุง

82
00:08:03,900 --> 00:08:09,140
ุฃูƒุชุฑูุฅุฐุง ุฏุฎู„ุช ุจุชูุงุตูŠู„ ุฃูƒุซุฑุŒ ูˆุญู„ุงู‚ูŠ ุฅู†ู‡ ููŠ ุญูˆุงู„ูŠ

83
00:08:09,140 --> 00:08:12,780
ู‡ู†ุง ุจุนุฏ ูˆุธู†ู†ูŠ ู‚ุงู„ูˆุง ุนุดุฑ ุฌูŠู†ุงุช ู…ูˆุฌูˆุฏุงุช ููŠ ู‡ุฐุง

84
00:08:12,780 --> 00:08:19,520
ุงู„ู…ูƒุงู† ูˆููŠ ุงู„ุบุงู„ุจ ุจู†ู„ุงุญุธ ุฅู†ู‡ ููŠ ุชู‚ุงุฑุจ ููŠ ูˆุธุงุฆู ู‡ุฐู‡

85
00:08:19,520 --> 00:08:25,120
ุงู„ุฌูŠู†ุงุชูููŠ ุงู„ุบุงู„ุจ ู‡ู†ุง ุจุชุชูƒู„ู…ูˆุง ุนู„ู‰ ุฅุดูŠ ุงุณู…ู‡ ุงู„ู€

86
00:08:25,120 --> 00:08:29,620
Olfactory Receptor Genes ูˆู‡ุฏูˆู„ุฉ ุฎู…ุณุฉ ุจุฌุงู†ุจ ุจุนุถ

87
00:08:29,620 --> 00:08:34,440
ูˆููŠู‡ ุฅุดูŠ ุงู„ู„ูŠ ุฏุฎู„ ุจุงู„ู€ Beta Globulin Genes ูˆููŠู‡

88
00:08:34,440 --> 00:08:39,320
ุฎู…ุณุฉ ู…ู†ู‡ู… ูˆู„ู…ู‘ุง ู†ูŠุฌูŠ ู†ู‚ุฑุฃู‡ุŒ ู†ู‚ุฑุฃ ุจู‡ุฐุง ุงู„ุดูƒู„ ูˆุจูƒูˆู†

89
00:08:39,320 --> 00:08:48,100
ู‡ูƒุฐุง ูู‡ุฐุง ุชุฑูƒูŠุจ ุงู„ู€ DNA ูˆุชุฑูƒูŠุจู‡ ุนู„ู‰ ู…ุณุชูˆู‰ ุฃูˆู„ ุดูŠุก

90
00:08:48,100 --> 00:08:52,560
ุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ูƒุฑู…ะพะทูˆู…ูˆุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ู€ Bands ุชุจุนุฉ ุงู„ู€

91
00:08:52,560 --> 00:09:01,120
Chromosome ูˆุนู„ู‰ ู…ุณุชูˆู‰ ุจุนุฏูŠู† ุงู„ู„ูŠ ุจู†ุณู…ูŠู‡ ุงู„ู‚ุฑุงุกุฉ

92
00:09:01,120 --> 00:09:04,200
ุงู„ุฏู‚ูŠู‚ุฉ ุชุจุนุชู‡ ุงู„ู„ูŠ ุจู†ุณู…ูŠู‡ุง ุงู„ู€ Sequencing ุชุจุนุชู‡

93
00:09:04,200 --> 00:09:10,100
ูู‡ุฐู‡ ุฏุฑุฌุงุช ุชุนู‚ูŠุฏ ุงู„ู…ูˆุถูˆุน ูˆุจุงู„ุชุงู„ูŠุŒ ุจุฏู„ ูˆุงุญุฏ ูŠูƒูˆู†

94
00:09:10,100 --> 00:09:19,180
ู…ุชู†ุจู‡ ู„ู‡ุง ู†ุฐูƒุฑ ู…ุฑุฉ ุซุงู†ูŠุฉ ุฅู†ู‡ ู…ู‚ุงุฑู†ุฉ ุจุงู„ู€ DNAุงู„ู„ูŠ

95
00:09:19,180 --> 00:09:23,040
ู‡ูˆ ุงู„ู€ Deoxyribonucleic Acid ุงู„ู„ูŠ ููŠู‡ ุงู„ู€

96
00:09:23,040 --> 00:09:30,240
Deoxyribose ูƒุดุฌุฑ ูˆูุณููŠุช ูˆุงู„ุฃุฑุจุน ู†ูŠูˆูƒู„ูŠูƒ ุฃุณุฏ ุฃูˆ

97
00:09:30,240 --> 00:09:36,220
ุงู„ุฃุฑุจุน ู†ูŠุชุฑูˆุฌูŠู†ูŠุณ ุจุงูŠุฒูŠุฒ ุงู„ู„ูŠ ู‡ูŠ ุงู„ู€ Purines

98
00:09:36,220 --> 00:09:43,900
ูˆุงู„ุจุฑูŠู…ุฏูŠู† ุงู„ู€ RNA ุชุฑูƒูŠุจู‡ ู…ุฎุชู„ู ููŠ ู†ุงุญูŠุชูŠู† ุฃุณุงุณูŠุฉ

99
00:09:43,900 --> 00:09:49,520
ุฃูˆู„ ุดูŠุกุฅู† ุงู„ุดุฌุฑ ู‡ูˆ ุงู„ู€ ยซุฑูŠุจูˆุฒยป ูˆู„ูŠุณ ุงู„ู€

100
00:09:49,520 --> 00:09:56,500
ยซุฃูƒุณูŠุฑูŠุจูˆุฒยป ุงู„ุจุฏู„ ู„ู„ุซุงู…ูŠู†

101
00:09:56,500 --> 00:10:04,140
ููŠ ุงู„ู€ ยซู†ูŠูˆุฑุงุณูŠู„ยป ูƒู€ ยซู†ูŠุชุฑูˆุฌูŠู†ุณ ุจูŠุณยป ูˆุทุจุนู‹ุง ูŠุชุบูŠุฑ

102
00:10:04,140 --> 00:10:09,280
ุฅู†ู‡ ููŠ ุงู„ุฌุณู… ุจุดูƒู„ ุทุจูŠุนูŠ ุฃูˆ ููŠ ุบุงู„ุจูŠุฉ ุงู„ูˆู‚ุช ุจุดูƒู„

103
00:10:09,280 --> 00:10:18,000
ุทุจูŠุนูŠ ูŠูƒูˆู† ุนู„ู‰ ุดูƒู„ Single Strandู…ู† ุฏุฑุงุณุฉ ุงู„ุฃู…ุฑุงุถ

104
00:10:18,000 --> 00:10:22,140
ุงู„ู„ูŠ ู‡ูŠ ุฒูŠ ุงู„ู€ ยซAutoimmune Diseasesยป ุฃู…ุฑุงุถ ุงู„ู…ู†ุงุนุฉ

105
00:10:22,140 --> 00:10:26,960
ุงู„ุฏุงุชูŠุฉ ุงู„ู„ูŠ ููŠู‡ ุนู†ุง Double-Stranded RNA ู…ู…ูƒู†

106
00:10:26,960 --> 00:10:33,960
ูŠุชุดูƒู„ ุจุดูƒู„ ุตู†ุงุนูŠ Single-Stranded DNA ูŠุนู†ูŠ ุจุชู„ุงู‚ูŠ

107
00:10:33,960 --> 00:10:39,280
ููŠู‡ ุฅู†ู‡ ุฃู†ุง ู…ู…ูƒู† ูŠูƒูˆู† ุนู†ุฏูŠ ุฃู†ูˆุงุน ุฃุฎุฑู‰ ูููŠ ุญุฏ ุนู†ุฏู‡

108
00:10:39,280 --> 00:10:46,240
ุณุคุงู„ so farู‡ุฐู‡ ุงู„ู„ูŠ ู‡ูŠ ุงู„ุงุฎุชู„ุงูุงุช ุจูŠู† ุงู„ู€ ยซRNAยป

109
00:10:46,240 --> 00:10:52,720
ูˆุงู„ู€ ยซDNAยป ุงู„ู€ ยซDNAยป ุจูŠุธู„ูˆุง ุฌูˆุง ุงู„ู†ูˆุงุก ุงู„ู€

110
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ยซNucleusยป ุงู„ู€ ยซRNAยป ุจูŠุชู… Transcription ู„ู‡ ุจูŠูƒูˆู† ู‡ูˆ

111
00:11:00,920 --> 00:11:07,330
ู„ุณู‡ ุฌูˆุง ุงู„ู†ูˆุงุก ุจูŠุชู… ุนู…ู„ูŠุฉ ู‚ุต ูˆ ู„ุตู‚ ู„ู‡ุจุญูŠุซ ุฅู†

112
00:11:07,330 --> 00:11:12,430
ุงู„ู€Full Messenger RNA ุงู„ู…ุทู„ูˆุจ ู‡ูˆ ุงู„ู„ูŠ ุจุชุชู… ุฅุฎุฑุงุฌู‡

113
00:11:12,430 --> 00:11:21,150
ูู‡ู†ุง ุฃู…ุซู„ุฉ ุนู„ู‰ ุฅู†ู‡ ุฅุญู†ุง ูƒุชูŠุฑ ููŠ ู‚ุถุงูŠุง ุงู„ุจุฑูˆุชูŠู†ุงุช

114
00:11:21,150 --> 00:11:27,870
ุงู„ู„ูŠ ุจุชูƒูˆู† ู…ููŠุฏุฉ ููŠ ุงู„ุฌุณู… ูˆุถุฑูˆุฑูŠุฉ ุจุชุชู… ู…ู† ุฎู„ุงู„

115
00:11:27,870 --> 00:11:34,750
ุงุณุชุฎุฏุงู… ู‚ุทุนุฉ ูƒุซูŠุฑุฉ ู…ู† ุงู„ู€DNA

116
00:11:34,750 --> 00:11:42,030
ุจุญูŠุซ ุฅู†ู‡ุงู„ู…ู†ุทู‚ุฉ ุงู„ู„ูŠ ูŠุชู… ุงุณุชุฎุฏุงู…ู‡ุง ููŠ ุนู…ู„ ุงู„ุจุฑูˆุชูŠู†

117
00:11:42,030 --> 00:11:47,510
ุจุณู…ูŠู‡ุง ุงู„ู€ Exon ุจุณุจุจ ุฃู† ู…ุซู„ู‹ุง ู‡ุฐู‡ ุงู„ู‚ุทุนุฉ ุจุฏู‡ุง

118
00:11:47,510 --> 00:11:53,670
ู…ุซู„ู‹ุง ุฃูˆู„ ุจุฑูˆุชูŠู† ู…ุซู„ู‹ุง ู‡ุฐุง ู„ู‡ ุฃุฑุจุน Exons ู…ุซู„ู‹ุง ุฃูŠ

119
00:11:53,670 --> 00:11:59,870
ู‡ู†ุง ููˆู‚ ูˆุงู„ู„ูŠ ุจูŠู†ู‡ู… ุจู†ุณู…ูŠู‡ ุงู„ู€ Introns ุงู„ู„ูŠ ู‡ู… ูŠุชู…

120
00:11:59,870 --> 00:12:08,890
ู‚ุตู‡ู… ูˆูŠุนู†ูŠ ุฑู…ูŠู‡ู…ูˆุจูƒูˆู† ูŠุนู†ูŠ ู„ู‚ู„ูŠุงุช ุฃูˆ ู„ู‡ุฏู ูŠุนู†ูŠ ู…ุง

121
00:12:08,890 --> 00:12:15,290
ุจุฃุนุฑูู‡ ุงู„ุขู† ุจุณ ุฅุญู†ุง ุงู„ู€ ยซู‡ูŠยป ุจุชูƒูˆู† step ุฃูˆ ู…ุฑุญู„ุฉ

122
00:12:15,290 --> 00:12:19,490
ุถุฑูˆุฑูŠุฉ ููŠ ุตู†ุงุนุฉ ูƒุซูŠุฑ ู…ู† ุงู„ุจุฑูˆุชูŠู†ุงุช ุฅู†ู‡ ุจุชูƒูˆู† ุฃูƒุซุฑ

123
00:12:19,490 --> 00:12:26,770
ู…ู† ู‚ุทุนุฉ ูˆุจุชุนุทูŠู†ุง ุชุญูƒู… ุฃูƒุจุฑ ููŠ ู†ุงุชุฌ ุงู„ุจุฑูˆุชูŠู†ูŠ ู…ู†

124
00:12:26,770 --> 00:12:31,090
ู‡ุฐุง ุงู„ู€Gene ูุงู„ู€ยซู‡ูŠยป ุจุดูƒู„ ุนุงู…

125
00:12:33,890 --> 00:12:40,390
ุญุชู‰ ุงู„ู‚ู„ูŠุงุช ุนู…ู„ูŠุฉ ุงู„ู€ Transcription ู„ู„ู€ DNA into

126
00:12:40,390 --> 00:12:48,150
RNA ุชุจุฏุฃ ุจุฏู‡ุง ุชูƒูˆู† ุฃูˆู„ ุดูŠุก ุชุชุนุฑู ุนู„ู‰ ู†ู‚ุทุฉ ุงู„ู„ูŠ ู‡ูŠ

127
00:12:48,150 --> 00:12:53,210
ุญุงุทูŠู†ู‡ุง ู‡ู†ุง ุจุงู„ุฃูˆู„ ุงุณู…ู‡ุง Start of Transcription

128
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ูŠุนู†ูŠ ููŠ ุนุงุฏุฉ ู„ูƒู„ ุฌูŠู† ููŠ ู…ู†ุทู‚ุฉ ููŠ ู…ู‚ุฏู…ุชู‡ุจูƒูˆู† ุงู„ู€

129
00:13:01,390 --> 00:13:07,370
Transcription Mechanism ุงู„ู…ูŠูƒุงู†ูŠูƒูŠุงุช ุฃูˆ ุขู„ูŠุงุช

130
00:13:07,370 --> 00:13:15,470
ุงู„ุนู…ู„ ุจุชูู‡ู…ูˆุง ุฅู†ู‡ ุงุจุฏุฃ ู…ู† ู‡ู†ุง ูˆุฑุงุญ ูŠูƒูˆู† ุฅู†

131
00:13:15,470 --> 00:13:21,190
ุงู„ู€Initiator Codon ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€Codon ุงู„ู„ูŠ ู‡ูˆ ุซู„ุงุซูŠ

132
00:13:21,190 --> 00:13:26,430
ุงู„ู€Nucleotides ุจุชุฑุชูŠุจ ู…ุนูŠู† ุจุชู‚ูˆู„ ุงุจุฏุฃ ู‡ู†ุง ูุจูŠุจุฏุฃ

133
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ูŠู‚ุฑุฃูˆู‡ุฐู‡ ุงู„ู€ Direction of Transcription ู„ุญุฏ ู…ุง ูŠุตู„

134
00:13:31,910 --> 00:13:37,550
ุจุงู„ุฃุฎูŠุฑ ุฅู„ู‰ ุงู„ู€ Termination Codon ุงู„ู„ูŠ ูŠู‚ูˆู„ ู„ู‡

135
00:13:37,550 --> 00:13:44,510
ูˆุงู‚ู ู‡ู†ุง ูˆุจุนุฏูŠู† ุญุชู‰ ูŠุญู…ูŠู‡ ูˆูŠู…ุดูŠ ุฎุทูˆุงุช ุฃุฎุฑู‰ ุจูŠูƒูˆู†

136
00:13:44,510 --> 00:13:50,930
ููŠู‡ Untranslated Region ูˆ Polyadenylation Signal

137
00:13:50,930 --> 00:13:56,230
ูˆููŠ ุฃุดูŠุงุก ุฅุถุงููŠุฉ ุญุชู‰ ุชุณุงุนุฏ ููŠ ุนู…ู„ูŠุฉ ุงู„ุชุญูƒู…ููŠ

138
00:13:56,230 --> 00:14:02,010
ุงู„ู€Transcription ุฅู„ู‰ ุงู„ู€Translation ุฅู„ู‰ ุงู„ู€Protein

139
00:14:02,010 --> 00:14:07,850
synthesis ูู…ุซู„ู‹ุงุŒ ุฏูƒุชูˆุฑุŒ ุฏูƒุชูˆุฑุŒ ู†ุนู… ูููŠ ุจุณ ุณุคุงู„ ู…ู†

140
00:14:07,850 --> 00:14:12,570
ุฏูƒุชูˆุฑ ู‡ุฏูŠู„ ู†ุนู… ุจุฎุตูˆุต ู…ุณุชูˆูŠุงุช ุชุฑูƒูŠุจ ุงู„ู€DNA ู†ุนู…

141
00:14:12,570 --> 00:14:17,510
ุจุชู‚ูˆู„ุŒ ุนู„ู‰ ุฃูŠ ุฃุณุงุณ ุตุงุฑูˆุง ุงู„ุซู„ุงุซุฉุŸ ู„ุฃุŒ ุฅุญู†ุง ู„ู…ุง

142
00:14:17,510 --> 00:14:24,790
ู†ุชูƒู„ู… ุนู† ุงู„ู€DNA ู‡ูˆ ู†ูุณู‡ ุฎุท ุทูˆูŠู„ูŠุนู†ูŠ ุจูŠู‚ูˆู„ู‘ูƒ ุฅุฐุง

143
00:14:24,790 --> 00:14:30,110
ุจุชู„ููŠู‡ Single Nucleotides ูˆุงุญุฏ ูˆุฑุง ุงู„ุซุงู†ูŠุŒ ุจูŠู„ู

144
00:14:30,110 --> 00:14:35,050
ุงู„ูƒูˆุฑุฉ ุงู„ุฃุฑุถูŠุฉุŒ ู…ุงุดูŠุŸ ูุฃู†ุง ุฅุฐุง ุจุฏูŠ ุฃุชุฎูŠู„ ูƒูŠู ุจุฏูŠ

145
00:14:35,050 --> 00:14:38,950
ุฃุชุนุงู…ู„ ู…ุนุงู‡ุŒ ู…ู…ูƒู† ุฃู†ุง ุจูƒูˆู† ููŠ ู…ุฑุญู„ุฉ ู…ุนูŠู†ุฉุŒ ููŠ ู„ุญุธุฉ

146
00:14:38,950 --> 00:14:44,230
ู…ุนูŠู†ุฉุŒ ุจุชูƒู„ู… ุนู† ูƒุฑูˆู…ุฒูˆู…ุงุชุŒ ูู‡ูˆ ุฃูŠ ุฌูŠู† ู…ูˆุฌูˆุฏ ุนู„ู‰

147
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ูƒุฑูˆู…ุฒูˆู… ู…ุนูŠู†ูููŠ ุฃุญุฏุงุซ ุชุฑุชุจุท ุจุงู„ู€ Chromosomes ูˆุงู„ู€

148
00:14:49,880 --> 00:14:53,980
Chromosomes ู…ู‡ู…ุฉ ุจู‡ุฐุง ุงู„ุดูƒู„ ุงู„ู…ุถุบูˆุท ุงู„ู„ูŠ ุจู†ุดูˆูู‡ ููŠ

149
00:14:53,980 --> 00:14:58,100
ู‡ุฐู‡ ุงู„ู„ุญุธุฉ ูŠุนู†ูŠ ู‡ูˆ ุงู„ู€ Chromosome ู…ุงุฑุญุด ู…ุงุดูŠุŒ ุจุณ

150
00:14:58,100 --> 00:15:06,500
ุดูƒู„ู‡ ุฒูŠ ูŠุนู†ูŠ ุฎูŠุท ูุงู„ุช ูˆู…ุด ู…ู„ููˆู ุจู‚ู‰ ุจุงู„ู€ Pistons

151
00:15:06,500 --> 00:15:12,200
ุจุดูƒู„ ู…ุถุบูˆุท ูƒุชูŠุฑ ุงู„ุฏุบุทุฉ ุงู„ุดุฏูŠุฏุฉ ู‡ูŠ ุฃู†ุง ุจุฏูŠู‡ุง ูˆู‚ุช

152
00:15:12,200 --> 00:15:19,360
ุงู„ู€ Cell Divisionููˆู‚ุชู‡ุง ุจุญุชุงุฌ ุงู„ูƒุฑูˆู…ูˆุฒูˆู… ูŠูƒูˆู† ุจู‡ุฐุง

153
00:15:19,360 --> 00:15:24,960
ุงู„ุดูƒู„ ุงู„ู„ูŠ ู‡ูˆ ุญุงุทู†ุงู‡ ููˆู‚ ูู„ู…ุง ุฃู†ุง ุฃุดูˆูู‡ ุจู‡ุฐุง ุงู„ุดูƒู„

154
00:15:24,960 --> 00:15:30,080
ู‡ู†ุง ุจุงู„ู…ุชูˆุณุท ูƒู„ู†ุง ูƒู„ ูƒุฑูˆู…ูˆุฒูˆู… ููŠู‡ ุญูˆุงู„ูŠ ุฃู„ู ุฌูŠู†

155
00:15:30,080 --> 00:15:34,860
ูุฃู†ุง ู…ู‚ุฏุฑุด ุฃุชุนุงู…ู„ ู…ุน ุงู„ุฃู„ู ุฌูŠู† ุฃุญูŠุงู†ุงู‹ ููŠู‡ ุธูˆุงู‡ุฑ

156
00:15:34,860 --> 00:15:42,860
ูˆุฃู…ุฑุงุถ ูˆุญุงู„ุงุช ุจุชูƒูˆู† ู‚ุทุนุฉ ู…ู†ู‡ ุจุณูˆู…ุฑุงุช ุงู„ูƒุฑู…ูˆุฒูˆู…ุงุช

157
00:15:42,860 --> 00:15:45,940
ุฒูŠ ู…ุง ู‡ู†ุง ุญุงุทูŠู† ุจูŠุณู…ูˆู‡ุง ุงู„ู€ Binding ู‡ุฐุง ุงู„ู€

158
00:15:45,940 --> 00:15:54,280
Binding ู‡ูŠ ู…ุฑุชุจุท ุจูƒู… ุนุฏุฏ ุงู„ุฌูŠู†ุงุช ููŠ ู‡ุฐู‡ ุงู„ู‚ุทุนุฉ ู…ู†

159
00:15:54,280 --> 00:16:01,320
ุงู„ู€ DNA ุฃูˆ ู…ู† ุงู„ูƒุฑู…ูˆุฒูˆู… ูˆุจุนุฏูŠู† ุจุฏุฑุฌุฉ ุฃุฏู‚ ูŠุนู†ูŠ ุงู„ู€

160
00:16:01,320 --> 00:16:08,000
Binds ุฅุดูŠ ุฌุงูŠ ุจุงู„ู†ุต ูŠุนู†ูŠ ู‡ุฐุง ุงู„ุขู† ุงู„ู„ูŠ ูŠุนู†ูŠ ุฏู‡

161
00:16:08,000 --> 00:16:15,150
ุจุฏู†ุง ู†ุชุฎูŠู„ ู‡ู†ุงุงู„ู€ Chromosome ู‡ุฐุง ุญูˆุงู„ูŠ ุฃู„ู ุฌูŠู† ุงู„ู€

162
00:16:15,150 --> 00:16:18,410
Band ุงู„ูˆุญุฏูŠ ู‡ู†ุง ุงู„ู„ูŠ ุญุงุทูŠู†ุง ู‡ูŠ ุนุจุงุฑุฉ ุนู† ุฎู…ุณุชุงุดุฑ

163
00:16:18,410 --> 00:16:23,330
ุฌูŠู† ุจุณ ุจุณ ุจุนุฏูŠู† ู„ู…ุง ุฃุฏุฎู„ ุฃู†ุง ุจุงู„ุชูุตูŠู„ ุทุจุนุงู‹ ู‡ู†ุง

164
00:16:23,330 --> 00:16:29,630
ุงู„ู€ Chromosome ู‡ุฐุง ู…ู‚ุณู… ุญูˆุงู„ูŠ ู…ุซู„ุงู‹ ู†ู‚ูˆู„ ุซู„ุงุซูŠู†

165
00:16:29,630 --> 00:16:35,770
Band ูƒู„ Band ู…ุซู„ุงู‹ ููŠู‡ุง ุนุดุฑูŠู†ุŒ ุซู„ุงุซูŠู† ุฌูŠู†ูˆุงู„ุฌูŠู†

166
00:16:35,770 --> 00:16:40,890
ุงู„ูˆุงุญุฏ ู„ุณู‡ ูƒู…ุงู† ู„ู‡ ุชุนู‚ูŠุฏ ุฌูˆุง ุฒูŠ ุงู„ู„ูŠ ุจู†ุดูˆูู‡ ู‡ู†ุง

167
00:16:40,890 --> 00:16:47,750
ูุฃู†ุง ุจุชูƒู„ู… ุนู„ู‰ ุฅู†ู‡ ุงู„ูˆุงุญุฏ ู„ุงุฒู… ูŠูƒูˆู† ู‡ูŠูƒ ู„ู…ุง ู†ู‚ุฑุง

168
00:16:47,750 --> 00:16:54,710
ุฃูŠ ู…ุนู„ูˆู…ุฉ ู…ุงุดูŠุŒ ุจุฏู‡ ู‡ูŠูƒ ุจุณุฑุนุฉ ูŠูู‡ู… ุดูˆ ุงู„ู…ู‚ุตูˆุฏ ู…ู†

169
00:16:54,710 --> 00:16:58,910
ุงู„ูƒู„ุงู… ู‡ุฐุง ุงู„ู„ูŠ ู‡ูˆ ุงุญู†ุง ุจู†ุชูƒู„ู… ุนู„ู‰ ู…ุณุชูˆู‰ ูƒู€

170
00:16:58,910 --> 00:17:04,360
Chromosome ููŠ Band ู…ุนูŠู†ุฉู†ุชุญุฏุซ ุนู† ู†ูุณ ุงู„ู€ ยซุฌูŠู†ยป

171
00:17:04,360 --> 00:17:12,240
ุงู„ู„ูŠ ุณู†ุชุญุฏุซ ุนู†ู‡ ู…ุซู„ู‹ุง ู…ุซู„ู‹ุง ุงู„ู€ ยซFMFยป ุงู„ู€ ยซFamily

172
00:17:12,240 --> 00:17:19,960
Mediterranean Feverยป ุฃุจุงุฑุนู‹ุง ยซุฌูŠู†ยป ุญูˆุงู„ูŠ ู†ุชุญุฏุซ ุนู†

173
00:17:19,960 --> 00:17:26,540
ู…ุฑูƒุจ ุงุณู…ู‡ ุงู„ู€ ยซุจุงูŠุฑูŠู†ยป ููŠู‡ ุญูˆุงู„ูŠ 11 ยซูƒูˆุฏูˆู†ยป 11 ุฃุณู

174
00:17:26,540 --> 00:17:33,550
ยซุฅูƒุฒูˆู†ยป ูŠุนู†ูŠ ููŠู‡11 ู‚ุทุนุฉ ูŠุชู… ู‚ุฑุงุฆุชู‡ุง ูˆู„ุณู‚ุฉ ูˆููŠู‡ุง

175
00:17:33,550 --> 00:17:40,210
ุญูˆุงู„ูŠ ุนุดุฑุฉ ุจุงู„ู†ุต ุฑุงุญ ูŠุทูŠุฑูˆุง ุงู„ุขู† ุงู„ู€ FMF ู‡ูŠ ุนุจุงุฑุฉ

176
00:17:40,210 --> 00:17:50,050
ุนู† ู…ุดูƒู„ุฉ ููŠ ุงู„ู€ Exons ุฑู‚ู… 2 ูˆุฑู‚ู… 10 ุฏูˆุงู‡ุฑ ุงู„ู„ูŠ

177
00:17:50,050 --> 00:17:55,670
ุนู†ุฏู‡ ูŠุนู†ูŠ ู„ูˆ ูˆุงุญุฏ ุนู†ุฏู‡ mutation ููŠ Exons ุชุงู†ูŠู†

178
00:17:55,670 --> 00:18:04,740
ู…ุงูŠูƒูˆู†ุด ุนู†ุฏู‡ ู…ุฑุถ ูุงุญู†ุง ู†ุชูƒู„ู… ุนู„ู‰ุงู„ุขู† ูˆุตู ู„ู…ุณุชูˆูŠุงุช

179
00:18:04,740 --> 00:18:11,240
ุงู„ุจุนุฏ ุนู† ู†ุธุฑ ุนู„ู‰ ุชุฑูƒูŠุจ ุงู„ู€DNA ูŠุนู†ูŠ ุจุฏุฃ ุญุฏุง ู…ู†ูƒู…

180
00:18:11,240 --> 00:18:17,660
ูŠุณุชุฎุฏู… ู…ุซู„ู‹ุง Google Earth ู…ุงุดูŠุŒ ู„ู…ุง ุฃู†ุช ุชุชูุฑุฌ ู…ู†

181
00:18:17,660 --> 00:18:21,120
ุงุฑุชูุงุน ุนุงู„ูŠ ุฌุฏู‹ุง ุฌุฏู‹ุง ุฌุฏู‹ุง ุนู„ู‰ ูƒู„ ุงู„ูƒูˆุฑุฉ ุงู„ุฃุฑุถูŠุฉ

182
00:18:21,120 --> 00:18:28,150
ูŠู…ูƒู† ูƒู„ ุงู„ู‚ุงุฑุฉ ุฏูˆุจุฉ ุชุดูˆูู‡ุง ุจู…ุณุชูˆู‰ ูˆุงุญุฏุจุนุฏูŠู† ุจุชู†ุฒู„

183
00:18:28,150 --> 00:18:33,690
ุจุดูƒู„ ุฃุฏู‚ ุจุชุตูŠุฑ ู…ุซู„ู‹ุง ุจู„ุฏ ุฒูŠ ูู„ุณุทูŠู† ุฃูˆ ุงู„ุฃุฑุฏู†

184
00:18:33,690 --> 00:18:37,690
ุจุชุชุจูŠู† ูƒู„ู‡ุง ููŠ ุงู„ุดุงุดุฉ ุจุญูŠุซ ุฃู†ู‡ ุจุชุตูŠุฑ ุงู„ู‚ุฑู‰

185
00:18:37,690 --> 00:18:44,370
ูˆุงู„ุฃุณู…ุงุก ุงู„ู…ุฏู† ุชุชุจูŠู† ุฃูƒุซุฑูˆุจุนุฏูŠู† ุจุชุฏุฎู„ ุจุฏู‚ุฉ ุฃูƒุซุฑุŒ

186
00:18:44,370 --> 00:18:48,930
ุจุชุตูŠุฑ ู…ุซู„ุง ูˆุงู„ู„ู‡ ุตูˆุฑุฉ ุงู„ุดุงุฑุนุŒ ุตูˆุฑุฉ ุงู„ุจูŠุชุŒ ุตูˆุฑุฉ

187
00:18:48,930 --> 00:18:53,830
ุงู„ูƒุฐุง ูุฃู†ุง ุจุชุชูƒู„ู… ุนู„ู‰ ู…ุณุชูˆูŠุงุช ุซู„ุงุซุฉ ุฃู†ุง ุจุงู„ู†ุณุจุฉ

188
00:18:53,830 --> 00:18:58,190
ุฅู„ูŠุŒ ุจุดุจู‡ู‡ุง ุฃู†ู‡ ุนู† ุฅูŠุด ุฃู†ุช ุจุชุชูƒู„ู… ุนู„ู‰ ู…ุณุชูˆู‰

189
00:18:58,190 --> 00:19:01,730
ุงู„ู€ChromosomeุŒ ุนู„ู‰ ู…ุณุชูˆู‰ Band ููŠ ุงู„ู€Chromosome

190
00:19:01,730 --> 00:19:05,570
ูˆููŠู‡ ุญูˆุงู„ูŠ ู…ุซู„ุง ุชู„ุงุชูŠู†ุŒ ุฃุฑุจุนูŠู†ุŒ ุฃุดุฑูŠู†ุŒ ุฃู‚ู„ ุฃูƒุซุฑ

191
00:19:05,570 --> 00:19:10,940
BandูˆุจุนุฏูŠู† ูƒู„ Band ููŠู‡ุง ุนุฏุฏ ู…ู† ุงู„ุฌูŠู†ุงุช ูˆุจุนุฏูŠู† ู„ู…ุง

192
00:19:10,940 --> 00:19:16,060
ุชุฏุฎู„ ููŠ ุงู„ุฌูŠู† ู…ุซู„ู‹ุงุŒ ู‡ุฐูˆู„ุฉ ุซู„ุงุซ ุฌูŠู†ุงุช ุจูŠุญุทูˆู†ู‡ุง ุงู„ู€

193
00:19:16,060 --> 00:19:21,180
Beta-Globulin ุชุจุน ุงู„ู€Hemoglobin ุงู„ู„ูŠ ู‡ูˆ ุชุจุน ุงู„ู€โ€ฆ

194
00:19:21,180 --> 00:19:24,000
ุงู„ู…ุนุฑูˆููŠู† ุงู„ู€2-Alpha-Chain ูˆ2-Beta-Chain ูˆููŠู‡

195
00:19:24,000 --> 00:19:32,120
BracaุŒ ู‡ุฐุง ุนุจุงุฑุฉ ุนู† ุฌูŠู† ู…ุณุฆูˆู„ ุฅุฐุง ููŠ ุฎู„ู„ ุนู† ุญุฏูˆุซ

196
00:19:32,120 --> 00:19:38,080
ุงู„ู€Cancerูุจุฑุงูƒุง I ูˆุจุฑุงูƒุง IIุŒ ุจุฑุงูƒุง I ูŠุนู†ูŠ ุฅุญู†ุง ุฑุงุญ

197
00:19:38,080 --> 00:19:43,780
ู†ุงุฎุฏ ุจุนุฏูŠู† ุฃู…ุซู„ุฉ ุนู„ูŠู‡ุง ูˆููŠ ุงู„ู€myocardial heart

198
00:19:43,780 --> 00:19:49,780
muscle gene ู†ุณู…ูŠู†ู‡ MyH7 ุงู„ู„ูŠ ุฏุฎู„

199
00:19:49,780 --> 00:19:54,160
ุจุงู„ู€cardiomyopathy inherited hypertrophic

200
00:19:54,160 --> 00:20:00,040
cardiomyopathy ูุงู„ุขู† ู‡ุฐุง ุฃู†ุง ุจุชูƒู„ู… ุนู„ู‰ ู…ุณุชูˆู‰

201
00:20:00,040 --> 00:20:07,430
ุงู„ู€DNAุฃู†ุง ุจุชูƒู„ู… ุงู„ู€ Globulin part ู…ุซู„ู‹ุง ุจูŠุจุฏุฃ ู‡ูˆู†

202
00:20:07,430 --> 00:20:14,990
ูŠู„ูˆ ุซู„ุงุซ Exons ููŠู‡ Two Introns ุงู„ู„ูŠ ุจุงู„ู†ุต ู‡ุฐูˆู„

203
00:20:14,990 --> 00:20:20,350
ุงู„ู„ูŠ ุฑุงุญ ูŠุทูŠุฑูˆุง ูˆู‡ูˆู†ุง ุงู„ุจุฏุงูŠุฉ ูˆู‡ูˆู†ุง ุงู„ู†ู‡ุงูŠุฉ

204
00:20:20,350 --> 00:20:28,410
ุงู„ุจุฑุงูƒุง ุงู„ุจุฑุงูƒุง ูŠุนู†ูŠ ุงู†ุชูˆุง ูƒู„ ู‡ุฐู‡ ุงู„ุฃุดูŠุงุก ูŠู…ูƒู†ูŠุนู†ูŠ

205
00:20:28,410 --> 00:20:32,330
ุฅุฐุง ุงู„ูˆุงุญุฏ ู…ุง ุจูŠุฑุจุทุงุด ุงู„ู‚ุตุฉ ู‡ูŠูƒูŠ ุจุชูุชูƒุฑู‡ ููŠ ุญุงู„ุฉุŒ

206
00:20:32,330 --> 00:20:39,550
ููŠ ุญุงุฌุฉ ูŠุนู†ูŠ ู‡ุฐุง ุนุจุงุฑุฉ ุนู† ุฌูŠู„ ู…ุดู‡ูˆุฑ ุฌุฏุงู‹ ู„ุฅุตุงุจุงุช

207
00:20:39,550 --> 00:20:44,150
ุณุฑุทุงู† ุงู„ุซุฏูŠ ูˆุณุฑุทุงู† ุงู„ุฑุญู… ุนู†ุฏ ุงู„ู†ุณุงุก ุจุงู„ุฐุงุช ูˆู‡ุฐู‡

208
00:20:44,150 --> 00:20:49,110
ู…ู…ุซู„ุฉ ู…ุดู‡ูˆุฑุฉ ุฌุฏุงู‹ ููŠ ุงู„ุนุงู„ู… Angelina Jolie ู‡ุฐู‡

209
00:20:49,110 --> 00:20:55,070
ุงู„ู„ูŠ ุนู…ู„ ููŠุฑ ูˆู„ูŠ ุฃูู„ุงู…ู‡ุงุŒ ู„ูˆ ุญุฏุง ูƒุงู† ุดุงุจ ูุงู„ู…ุฑูŠุถุฉ

210
00:20:55,070 --> 00:20:57,430
ู‡ุฐู‡ ูˆุงู„ุฏุชู‡ุง ููŠ ุนู†ุฏู‡ุง

211
00:21:03,710 --> 00:21:08,990
ุนุดุงู† ู‡ูŠ ุนู…ู„ุช ุจูŠู„ุงุชุฑุงู„ ู…ุณุชูƒุชูˆู…ูŠ ุนู„ู‰ ุถูˆุก ุฅู†ู‡ ุทู„ุน ุงู„ู€

212
00:21:08,990 --> 00:21:15,450
mutation ููŠ ู‡ุฐุง ุงู„ุฌูŠู† ู…ูˆุฌูˆุฏ ูููŠู‡ ุฌูŠู† ุงุณู…ู‡ Braca

213
00:21:15,450 --> 00:21:23,970
ุฅู„ู‡ ุฏุฎู„ ุจุงู„ูƒุงู†ุณุฑ ูˆุงู„ู€ MyH7 ุฅู„ู‡ ุญุงู„ุฉ ุฏุฎู„ ููŠ ุญุงู„ุฉ

214
00:21:23,970 --> 00:21:29,730
ุงู„ู„ูŠ ู‡ูŠุชุถุฎู… ุนุถู„ุฉ ุงู„ู‚ู„ุจ ุจุญูŠุซ ุฃู†ู‡ ุชู„ุงู‚ูŠ ุงู„ู„ูŠ ุฅุฐุง

215
00:21:29,730 --> 00:21:33,990
ุจุชู„ุงู‚ูŠ ุจูŠู‚ูˆู„ูƒ ู„ุงุนุจ ูƒุฑุฉ ู‚ุฏู… ูˆู‡ูˆ ุตุบูŠุฑ ู…ุงุนู†ุฏู‡ูˆุด ุณูƒุฑูŠ

216
00:21:33,990 --> 00:21:39,430
ูˆู„ุง ุถุบุท ูุฌุฃุฉ ุงู„ุทุจ ูƒู„ู‡ ุงู„ุทุจ ุณุงูƒู† ูุจูŠุตูŠุฑ ุนู†ุฏู‡ ุงูุชู„ุงู„

217
00:21:39,430 --> 00:21:44,970
ููŠ ู†ุธู… ุงู„ู‚ู„ุจ ุจูŠุตูŠุฑ ุนู†ุฏู‡ู… ูˆูุงุฉ ู…ูุงุฌุฆุฉ ูˆุจูŠู‚ูˆู„ ุฃู†ู‡

218
00:21:44,970 --> 00:21:49,470
ุฏุฎู„ ููŠ ุญุงู„ุฉ ูˆุฑุงููŠุฉ ุงู„ู„ูŠ ู‡ูŠ ุงู„ุญุงู„ุฉ ุงู„ู„ูŠ ุจุชูƒูˆู†

219
00:21:49,470 --> 00:21:53,560
ุญุงู„ุชู‡ุง ูŠุนู†ูŠ ุฃุญูŠุงู†ุงู‹ุชุถุฎู… ุงู„ู‚ู„ุจ ู‡ุฐุงุŒ ุจูŠูƒูˆู† ู…ุด ูˆุฑุงุซูŠ

220
00:21:53,560 --> 00:21:57,440
ุจุณ ุงู„ุญุงู„ุฉ ุงู„ูˆุฑุงุซูŠุฉ ุจุชูƒูˆู† ุฅู„ู‡ุง ุฏุฎู„ ุจู‡ุฐุง ุงู„ู€Gene

221
00:21:57,440 --> 00:22:03,280
ู…ู„ุงุญุธุฉ ูŠุนู†ูŠ ุฃุฎูŠุฑู‹ุง ุชุจู‚ูˆุง ุนู„ูŠู‡ุง ุชูุถู„ ุงู„ู„ูŠ ู‡ูŠ ุฅู†

222
00:22:03,280 --> 00:22:07,360
ุฃุณู…ุงุก ุงู„ุฌูŠู†ุงุช ู„ู…ุง ู†ุญูƒูŠ ุนู† ุงู„ุฌูŠู†ุงุช ุจูŠุญุทูˆู‡ุง ูƒู„ู‡ุง

223
00:22:07,360 --> 00:22:11,900
Capital Letters ููŠ ุงู„ู†ู‡ุงูŠุฉ ู„ู…ุง ูŠู‚ุนุฏูˆุง ูŠุดุฑุญูˆุง ุนู„ู‰

224
00:22:11,900 --> 00:22:16,280
ุฅู† ุงู„ุดุบู„ ุงู„ุฅูู„ุงู†ูŠ ุจูŠุญุท ู„ูƒูŠู‡ุง ูƒู„ู‡ุง Capital ูู‡ูˆ ู‚ุตุฏู‡

225
00:22:16,280 --> 00:22:22,000
ุงู„ู€GeneุŒ ู…ุงุดูŠุŸ ููŠ ุณุคุงู„ ุซุงู†ูŠ ุงุณุฃู„ู‡ููŠ ุณุคุงู„ ู…ู†

226
00:22:22,000 --> 00:22:26,060
ุงู„ุฏูƒุชูˆุฑุฉ ุฃุณู…ุงุก ุจุฎุตูˆุต ุงู„ู€ยซุจูˆู„ูŠ ุฃุฏูŠู†ุงู„ูŠุงุดู†ยป ุจุชู‚ูˆู„

227
00:22:26,060 --> 00:22:32,180
ุฃู†ู‡ ุฃุฎุฏูˆุง ู‚ุจู„ ุฐู„ูƒ ุฃู† ูŠุชู… ุฅุถุงูุฉ ุงู„ู€Nucleotide A ุจุนุฏ

228
00:22:32,180 --> 00:22:36,460
ุนู…ู„ูŠุฉ ุฅุฒุงู„ุฉ ุงู„ุงู†ุชุฑูˆู† ูˆู„ูƒู† ููŠ ุงู„ุตูˆุฑุฉ ุจูŠุชู… ุฅุถุงูุฉ

229
00:22:36,460 --> 00:22:44,620
ุงู„ู€A ู‚ุจู„ ุฅุฒุงู„ุฉ ุงู„ุงู†ุชุฑูˆู† ูˆุงู„ู„ู‡ ููŠ ุงู„ุตูˆุฑุฉ ู…ุจูŠู† ุฅู†ู‡

230
00:22:44,620 --> 00:22:46,400
ููŠ ุงู„ู€ยซุฃุฏูŠู†ุงู„ูŠุงุดู†ยป Signal

231
00:22:49,050 --> 00:22:54,190
ู…ูˆุฌูˆุฏุฉ ู‚ุจู„ ู…ุง ูŠุชู… ุนู…ู„ูŠุฉ ุชู‚ุทูŠุน ุงู„ู€ ExonsุŸ ูŠู…ูƒู†ุŒ

232
00:22:54,190 --> 00:23:00,670
ูŠู…ูƒู†ุŒ ุฃู†ุงุŒ ุดูˆูุŒ ู…ูŠุฉ ุจุงู„ู…ูŠุฉุŒ ุจู„ุงุด ู†ุฏุฎู„ ุงู„ุชูุงุตูŠู„ุŒ

233
00:23:00,670 --> 00:23:06,110
ุฃู†ุง ู…ุงุนู†ุฏูŠ ุนู„ู… ุฃู‚ูˆู„ูƒ ู‡ูŠูƒ ุจูŠุตูŠุฑ ุฃูˆ ู‡ูŠูƒ ุจูŠุตูŠุฑุดุŒ ุจุณ

234
00:23:06,110 --> 00:23:13,350
ุงู„ู…ู„ุงุญุธ ูŠุนู†ูŠ ู„ู…ุง ุชูŠุฌูŠ ุงู„ุตูˆุฑุฉ ู‡ุฐู‡ ู…ุงุดูŠุฉุŒ ุงู„ู„ูŠ ู‡ูŠ

235
00:23:13,350 --> 00:23:20,180
ุจุชุชูƒู„ู… ุฃูƒุซุฑ ุนู† ุงู„ู†ุงุญูŠุฉ ู‡ุฐู‡ุŒุฅู†ู‡ ุจุทุฑูŠู‚ุฉ ู…ุง ุงู„ู€

236
00:23:20,180 --> 00:23:25,640
ยซhighยป ุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ู€ ยซDNAยป ุจุฏู‘ูƒ ุชูุฑุทู‡ ูˆุชุจุนุฏู‡ ุนู†

237
00:23:25,640 --> 00:23:31,680
ุจุนุถ ุญุชู‰ ุชูุนู„ ุงู„ู€ Transcription ูˆุชู…ุดูŠ ู…ู† ุงู„ู€ ยซ5

238
00:23:31,680 --> 00:23:36,920
Endยป ู„ู€ ยซ3 Endยป ุฏุงุฆู…ุงู‹ุŒ ู…ู† ยซ5 Primeยป ู„ู€ ยซ3 Primeยป

239
00:23:36,920 --> 00:23:42,630
ูููŠ ู‡ู†ุง ุงู„ู€ ยซStartupยปูˆููŠ ุงู„ู€ Promoter Region ุงู„ู€

240
00:23:42,630 --> 00:23:46,930
Promoter Region ุดูˆูŠุฉ ู…ู†ุทู‚ุฉ ุฃู‚ุนุฏ ุดูˆูŠุฉ ู„ู‚ุฏุงู… ูˆุงู„ู„ูŠ

241
00:23:46,930 --> 00:23:51,690
ู‚ุตุฏ ููŠู‡ุง ุฅู†ู‡ุง ุชู†ุจู‡ ุงู„ู€ Transcription Mechanism

242
00:23:51,690 --> 00:23:55,510
ู‡ุงู„ูŠุงุช ุงู„ู€ Transcription ุฅู†ู‡ ุงุจุฏุฃ ู…ู† ู‡ูˆู†ุŒ ููŠู‡ ู‡ู†ุง

243
00:23:55,510 --> 00:24:00,190
ุฅุดูŠ ูˆููŠ ุงู„ู€ Startup Codon ุงู„ู„ูŠ ู‡ูˆ ุจูŠู‚ูˆู„ูƒ ุงุจุฏุฃ ู‡ู†ุง

244
00:24:00,190 --> 00:24:09,700
ูุจุชู… ู†ุณุฎ ุงู„ู€ RNAูƒู„ู‡ ุจู…ุง ููŠู‡ ุงู„ู€ Exon ุงู„ู„ูŠ ู‡ู… ู‡ุฐูˆู„ุฉ

245
00:24:09,700 --> 00:24:15,880
ุงู„ู…ููŠุฏุงุช ูˆุงู„ู€ Intron ุงู„ู„ูŠ ุจุฏู‡ู… ุงู†ู‚ุทุนู‡ ูˆุจุชู… ุฅุถุงูุฉ

246
00:24:15,880 --> 00:24:24,940
ุจุนุฏูŠู† ยซุฐูŠู„ยป ู…ุงุดูŠ ุฃู†ุง ุจูู‡ู… ุฅู† ู‡ุฐุง ูŠุชู… ุงู„ุงุณุชูุงุฏุฉ ู…ู†ู‡

247
00:24:24,940 --> 00:24:32,760
ููŠ ู‚ุถูŠุฉ ุชุญุฑูŠูƒ ุงู„ู€ Messenger RNA ุฎุงุฑุฌ ุงู„ู†ูˆุงุฉ ุงู„ู€

248
00:24:32,760 --> 00:24:38,180
TranscriptionุจูŠูƒูˆู† ุฎู„ุงู„ ุงู„ู†ูˆุงุฉ ูˆุงู„ู€Alternative

249
00:24:38,180 --> 00:24:44,480
Splicing ุฃูˆ Processing of the RNA ุจุญูŠุซ ุฅู†ู‡ ู‡ุฐูˆู„ุฉ

250
00:24:44,480 --> 00:24:52,200
ุงู„ู€Introns ุจุชู… ู‚ุตู‡ู… ูˆุงู„ู€Exons ุจุชู… ูˆุตู„ู‡ู… ู…ุน ุจุนุถุŒ

251
00:24:52,200 --> 00:24:55,840
ุจุญูŠุซ ูŠุนุทูŠู†ูŠ ู‡ุฐุง ุงู„ู„ูŠ ุฑุงุญ ูŠูƒูˆู† ู…ุณุคูˆู„ ุนู† ุงู„ุจุฑูˆุชูŠู†

252
00:24:55,840 --> 00:25:01,060
ุงู„ู†ู‡ุงุฆูŠุŒ ู‡ุฐุง ูŠุนู†ูŠ ุงู„ู„ู‡ ุฃุนู„ู… ูŠู…ูƒู† ุงู„ู€Poly-A tail

253
00:25:02,850 --> 00:25:10,910
ู…ุทู„ูˆุจ ุนุดุงู† ูŠุชู… ุณู‡ูˆู„ุฉ ุชุฎุฑูŠุฌู‡ ู…ู† ุงู„ู†ูˆุงุฉ ุญุชู‰ ูŠุฏุฎู„

254
00:25:10,910 --> 00:25:14,250
ุงู„ู€Cytoplasm ูˆูŠุฑูˆุญ ุนู„ู‰ ุงู„ู€Rough Endoplasmic

255
00:25:14,250 --> 00:25:19,250
Reticulum ูˆูŠุฑูˆุญ ุนู„ู‰ ุบูŠุฑู‡ ูˆูŠู‚ุฏุฑ ุจุนุฏูŠู† ูŠุฌูŠ ุฌู†ุจู‡

256
00:25:19,250 --> 00:25:27,050
ุงู„ู€Ribosome ุงู„ู„ูŠ ุฑุงุญ ุฒูŠ ุณุญุงุจ ุงู„ุจู†ุทู„ูˆู† ุฃูˆ ุณุญุงุจ

257
00:25:27,050 --> 00:25:35,020
ุงู„ุฌุงูƒูŠุช ุฃุญูŠุงู†ู‹ุง ูˆู„ุง ุฅุดูŠุจุตูŠุฑุŒ ุจู…ุณูƒ ุงู„ู€ ุงู„ู€ ูƒู„ ุซู„ุงุซุฉ

258
00:25:35,020 --> 00:25:39,240
ุงู„ู€ nucleotides ูˆุจูŠู‚ุฑุงู‡ู… ูˆุจูŠุญุท ุงู„ู€ amino acid

259
00:25:39,240 --> 00:25:44,280
ุงู„ู„ุงุฒู… ู„ุญูŠุซ ุฅู†ู‡ ุจูŠุจู†ูŠ ุงู„ู€ amino acid chain

260
00:25:44,280 --> 00:25:48,440
ุงู„ู…ุทู„ูˆุจุฉ ุงู„ู„ูŠ ู‡ูŠ ุงู„ู€ growing polypeptide chain

261
00:25:48,440 --> 00:25:54,540
ูุงู„ู€ ุงู„ู€ ุงู„ู€ terminal poly-A addition ู…ุงุดูŠุŒ ุธุงู‡ุฑุฉ

262
00:25:54,540 --> 00:26:02,660
ุจุชุญุฏุซ ูˆุงู„ู„ู‡ ู…ุง ุจุนุฑู ุดูˆ ู‡ู…ูŠุชู‡ุง100% ูŠุนู†ูŠ ู…ุง ุจุนุฑู ุฅุฐุง

263
00:26:02,660 --> 00:26:08,700
ููŠ ู…ุซู„ู‹ุง ู†ุงุณ ุนู†ุฏู‡ู… ุฃู…ุฑุงุถ ู†ุชูŠุฌุฉ ุฅู†ู‡ุง ู„ุง ุชุชู… ุฃูˆ ุดูˆ

264
00:26:08,700 --> 00:26:12,240
ุฏูˆุฑุฉุŒ ุจุณ ู‡ุงูŠ ุดุบู„ุฉ ูŠุนู†ูŠ ุงู„ู„ู‡ ุงู„ุนู„ูŠู… ุฅู†ู‡ุง ู„ูƒู„

265
00:26:12,240 --> 00:26:15,760
ุงู„ุฌูŠู†ุงุช ุฃูˆ ู„ุนุฏุฏ ูƒุจูŠุฑ ู…ู† ุงู„ุฌูŠู†ุงุชุŒ ุจู„ุงุด ุฃู‚ูˆู„ ูƒู„

266
00:26:15,760 --> 00:26:27,040
ุงู„ุฌูŠู†ุงุชุŒ ูˆุงุถุญุŸ ููŠ ุฃุณุฆู„ุฉุŸูู‡ุฐู‡ ุงู„ุธูˆุงู‡ุฑ ุงู„ู„ูŠ ุงู„ูˆุงุญุฏ

267
00:26:27,040 --> 00:26:37,700
ุจุฏู‡ ูŠุชุฐูƒุฑู‡ุง ุงู„ู€ Expression ุฃูˆ ุงู„ู…ุธู‡ุฑูŠู‹ุง ุงู„ุฌูŠู†

268
00:26:37,700 --> 00:26:44,960
ู…ุณุคูˆู„ ุนู† ุงู„ุจุฑูˆุชูŠู† ูˆุจุชู… ู‡ุฐู‡ ุงู„ู…ุณุคูˆู„ูŠุฉ ูˆุจุชู… ู‡ุฐู‡

269
00:26:44,960 --> 00:26:51,400
ุงู„ุธุงู‡ุฑุฉ ู…ู† ุฎู„ุงู„ ุงู„ุฎุทูˆุงุช

270
00:26:51,400 --> 00:26:57,980
ู‡ุฐู‡ TranscriptionูˆุจุนุฏูŠู† RNA Processing ุชู‚ูˆู… ู‡ู†ุง

271
00:26:57,980 --> 00:27:01,420
ุจุงู„ู€ Transport ู„ุงุฒู… ุชูƒูˆู† ู…ู† ุฌูˆู‡ ุงู„ุฎู„ูŠุฉ ู„ุจุฑู‡ ุงู„ุฎู„ูŠุฉ

272
00:27:01,420 --> 00:27:05,840
ุจูŠุตูŠุฑ ุนู†ุฏู‰ ุนู…ู„ูŠุฉ ุงู„ู€ Translation ู…ู† ุงู„ู€ Messenger

273
00:27:05,840 --> 00:27:10,700
RNA ู„ู€ Polypeptide Chain ูˆุจุนุฏูŠู† ุจูŠุตูŠุฑ ุนู†ุฏ ุงู„ู€

274
00:27:10,700 --> 00:27:13,840
Protein Assembly ุงู„ู„ูŠ ู‡ูˆ ุฑุงุญ ูŠู‚ุฏู‘ู„ ูˆุธูŠูุฉุŒ ุฑุงุญ

275
00:27:13,840 --> 00:27:20,040
ูŠู‚ุฏู‘ู„ ุงู„ุดูŠุก ุงู„ู…ุทู„ูˆุจุŒ ู…ุงุดูŠุŸ ู‡ุงูŠ ุงู„ู„ูŠ ูŠุนู†ูŠ ุณู…ูˆู‡ุง ู‡ูˆ

276
00:27:20,040 --> 00:27:23,620
ู‡ู†ุง ุงู„ู€ Flow of Informationู…ู† ุฏูŠุงู†ุงุช ูˆุงุฑุงู†ุงุช

277
00:27:23,620 --> 00:27:33,080
ูˆุจุฑูˆุชูŠู† ุนู„ู‰ ุฅุดูŠ ุงูุชุฑุงุถูŠุŒ ู…ุงุดูŠุŸ ุงู„ุขู†ุŒ

278
00:27:33,080 --> 00:27:40,940
ูƒูŠู ุงู„ู€DNA ู…ุณุฆูˆู„ ุนู† ุงู„ุจุฑูˆุชูŠู†ุŸ

279
00:27:40,940 --> 00:27:48,360
ู†ุชุฐูƒุฑ ุฅู† ุฃู†ุง ุนู†ุฏูŠ ุฃุฑุจุน ู†ูŠูƒู„ูŠูƒ ุฃุณู†ุฏ ุฃูˆ ู†ูŠูƒู„ูŠูˆุชุงูŠุฏ

280
00:27:48,360 --> 00:27:53,710
ุฃูˆ Nitrogenous basesูุงู„ุฃุฑุจุนุฉ ุงู„ู€ Nucleotides ุทุจุนู‹ุง

281
00:27:53,710 --> 00:28:00,650
ุฌุงูŠูŠู† ุจุชุฑุชูŠุจ ุฅู†ู‡ ูƒู„ ูˆุงุญุฏ ู„ุงุฒู… ูŠู‚ุงุจู„ู‡ ุฅุด ู…ุญุฏุฏ ูุฅุญู†ุง

282
00:28:00,650 --> 00:28:05,130
ุจู†ุญูƒูŠ ุนู† ุตู ูˆุงุญุฏุŒ ู…ู† ุฌู‡ุฉ ูˆุงุญุฏุฉ ู„ุณู‡ ุงู„ู„ูŠ ู‡ูŠ ู…ู†

283
00:28:05,130 --> 00:28:10,430
ุงู„ุฎู…ุณุฉ ู„ู„ุซู„ุงุซุฉ ุงู„ู„ูŠ ุฑุงุญ ูŠูƒูˆู† ู…ู† ุฎู„ุงู„ู‡ุง ุนู…ู„ูŠุฉ

284
00:28:10,430 --> 00:28:18,650
ุงู„ู‚ุฑุงุกุฉ ุจู‡ุฐุง ุงู„ุชุฑุชูŠุจ ู†ุชุฐูƒุฑ ุดุบู„ุฉ ุฃูˆู„ ุดูŠุก ุงุณุชู†ุชุฌูˆู‡ุง

285
00:28:18,650 --> 00:28:28,170
ุญุณุงุจูŠุงู‹ูˆุจุนุฏูŠู† ุชุจุฏุฃ ุจุงู„ูˆุงู‚ุน ูˆุจุงู„ู…ุดุงู‡ุฏุงุช ูˆุจุงู„ุชุฌุงุฑุจ

286
00:28:28,170 --> 00:28:34,370
ูˆูƒุฐุง ู„ูˆ ุงูุชุฑุถู†ุง ุทุจุนุงู‹ ุฃู†ุง ุจุนุฑู ุฃู†ู‡ ุฃู†ุง ูƒู€ Protein

287
00:28:34,370 --> 00:28:41,870
Structure ููŠ ุนู†ุฏูŠ 20 Amino Acids ูˆู‡ูŠ ุฃุณุงู…ูŠู‡ู… ูˆูŠู„ู‡ู…

288
00:28:41,870 --> 00:28:47,170
ุทุฑูŠู‚ุฉ ูƒุชุงุจุชู‡ู… ูˆุฑุงุญ ู†ู‚ุฑุฃ ุนู†ู‡ู… ุจุนุฏูŠู† ููŠ ุซู„ุงุซ ุทุฑู‚

289
00:28:47,170 --> 00:28:54,190
ู…ู…ูƒู†ู†ุญุท ุซู„ุงุซ ุฃุญุฑู ยซู„ูˆุณูŠู†ยป ู‡ุฐุง ุงู„ุฅุณู… ุงู„ูƒุงู…ู„ ุชุจุนู‡

290
00:28:54,190 --> 00:28:59,650
ูˆููŠ ุฃุญูŠุงู†ู‹ุง ุจูŠุฑู…ุฒูˆุง ู„ู„ู€ Amino Acid ุจุญุฑู ูˆุงุญุฏ ุงู„ู„ูŠ

291
00:28:59,650 --> 00:29:05,490
ู‡ูˆ ุงู„ู€ ยซLยป ู„ู…ุง ู†ุญุทู‡ ยซKยป ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€ ยซLysineยป ู‡ุฐุง

292
00:29:05,490 --> 00:29:10,550
ุงุณู…ู‡ุŒ ู‡ุฐุง ูƒู„ู‡ู… Amino Acids ุทุจุนู‹ุง ุงู„ู€ Amino Acid

293
00:29:10,550 --> 00:29:15,920
Structure ู„ุงุฒู… ุชูƒูˆู†ูˆุง ุนุงุฑููŠู† ููŠุงู„ู€ Carboxyl

294
00:29:15,920 --> 00:29:20,120
Terminal ูˆููŠ ุงู„ู€ Nitrogen Terminal ููŠ ุงู„ู€ N

295
00:29:20,120 --> 00:29:25,660
Terminal ูŠุนู†ูŠ ุงู„ู€ Backbone ูŠุนู†ูŠ ุฅุดูŠ ู‚ุฑูŠุจ ู…ู† ุงู„ู€ ู…ู†

296
00:29:25,660 --> 00:29:32,020
ุงู„ู€ DNA ูŠุนู†ูŠ ุฅุฐุง ุชุฎูŠู„ู†ุง ุงู„ู€ DNA ุงู„ู€ DNA ุฏูŠูˆูƒุณูŠ

297
00:29:32,020 --> 00:29:36,380
ุฑุงูŠุจูˆุฒ ููˆุณููŠุช ุฏูŠูˆูƒุณูŠ ุฑุงูŠุจูˆุฒ ููˆุณููŠุช ุฏูŠูˆูƒุณูŠ ุฑุงูŠุจูˆุฒ

298
00:29:36,380 --> 00:29:42,820
ููˆุณููŠุช ูˆููŠ ุงู„ู†ุตุฑ ุจูŠู†ู‡ู… ููŠ ุงู„ู€ Nitrogen Space ุจุณ

299
00:29:42,820 --> 00:29:49,120
ุงู„ู€ุงู„ู€ Amino Acids ู…ุงุดูŠุŒ ุนุจุงุฑุฉ ุนู† ููŠู‡ Carboxyl

300
00:29:49,120 --> 00:29:54,660
Terminal ุงู„ู„ูŠ ุฏุงูŠู…ุงู‹ ุจู†ุจุฏุฃ ุจูŠุจุฏูˆ ุจุงู„ู€ N Terminal

301
00:29:54,660 --> 00:29:59,720
ุงู„ู„ูŠ ู‡ูŠ ุงู„ุจุฏุงูŠุฉ ูˆุจูŠุฌูŠ ุจุนุฏูŠู† ุงู„ู€ Carboxyl Terminal

302
00:29:59,720 --> 00:30:06,440
ุชุจุนุชู‡ุง ุจุงู„ุทุฑู ููŠู‡ Side Chain Side Chain ู‡ูŠ ุงู„ู„ูŠ ู‡ูŠ

303
00:30:06,440 --> 00:30:12,120
ุจุชุณูˆูŠ ุงู„ุงุฎุชู„ุงูุงุช ุจูŠู† ุงู„ู€ Amino Acids ูููŠ ุนู†ุฏู†ุง

304
00:30:12,120 --> 00:30:18,430
Structure ู…ุชูƒุฑุฑุงู„ู„ูŠ ู‡ูˆ Nitrogen-based terminal

305
00:30:18,430 --> 00:30:22,270
ูˆCarboxyl terminal ู†ูŠุชุฑูˆุฌูŠู† ุชูŠุฑู…ูŠู†ุงู„ ูˆCarboxyl

306
00:30:22,270 --> 00:30:26,710
terminal ูˆุงู„ู€ Side Chain ู‡ู… ุงู„ู„ูŠ ุจูŠุนุทูŠู†ุง ุงู„ุฎูˆุงุต

307
00:30:26,710 --> 00:30:31,110
ุงู„ุฃุฎุฑู‰ ูˆุงู„ุชูุงุนู„ุงุช ุงู„ุฃุฎุฑู‰ ูˆุงู„ุฃุดูŠุงุก ู‡ุฐู‡ ูุฃู†ุง ุจู…ุง ุฃู†ู‡

308
00:30:31,110 --> 00:30:35,330
ุฃู†ุง ุนู†ุฏูŠุŒ ู‡ุฐู‡ ู…ุฑุงุฌุนุฉ ุดูˆูŠุฉ ู„ู„ู€Biochemistry ุจู…ุง ุฃู†ู‡

309
00:30:35,330 --> 00:30:42,470
ุฃู†ุง ุนู†ุฏูŠ ุฃุดุฑูŠู† Amino Acid ู„ูˆ ูƒุงู† ูƒู„ Amino Acid ู‡ูˆ

310
00:30:42,470 --> 00:30:48,560
ู†ุชูŠุฌุฉู‚ุฑุงุฉ ู†ูŠูƒู„ูŠูˆุชุงูŠุฏ ูˆุงุญุฏ ุฃูˆ Nitrogen Base ูˆุงุญุฏุฉ

311
00:30:48,560 --> 00:30:53,700
ูƒุงู† ุฑุงุญ ูŠูƒูˆู† ุฅู†ู‡ ุฃู†ุง ุนู†ุฏูŠ ุฃุฑุจุน Nitrogen Bases ุฑุงุญ

312
00:30:53,700 --> 00:31:00,560
ูŠูƒูˆู†ูˆุง ู…ุณุฆูˆู„ูŠู† ุนุฏูุฉ ุนู† ุฃุฑุจุน Amino Acids ุจุงู„ุชุงู„ูŠุŒ

313
00:31:00,560 --> 00:31:08,160
ู…ุง ุจุธุจุทุŒ ู…ุง ุฑุงุญ ูŠูƒูˆู† ูƒุงููŠุŒ ูู„ูˆ ูƒู†ุง ุฃุซู†ูŠู†ุงู„ู€2 ุฅุจุงุฑุฉ

314
00:31:08,160 --> 00:31:12,780
ุนู† 4ร—4 ุตุงุฑุช ุงู„ุงุญุชู…ุงู„ูŠุงุช ุฃุญุณู† ุจู„ ุงู„ู€16 ู„ุณุฉ ู…ุง ุจูŠูƒููŠ

315
00:31:12,780 --> 00:31:24,500
ุงู„ู€20 ุฃู…ุงุฆู† ูˆุงุณุฑ ููƒุงู†ุช ุงู„ู†ุชูŠุฌุฉ ุฃู†ู‡ ูุนู„ูŠู‹ุง

316
00:31:24,500 --> 00:31:31,320
ูƒู„ 3 ุฃู…ุงุก ุงู„ู€Nitrogenous Bases ูƒู„ 3 ู†ูŠูƒู„ูŠูˆุชุงูŠุฏ

317
00:31:31,320 --> 00:31:35,760
ุจุงู„ุชุฑุชูŠุจ ุงู„ู„ูŠ ู‡ู… ู…ูˆุฌูˆุฏูŠู† ููŠู‡ ุจูŠูƒูˆู†ูˆุง ู…ุณุคูˆู„ูŠู† ุนู†

318
00:31:37,960 --> 00:31:44,900
ุจุชุญุฏูŠุฏ ุงู„ู€ Amino Acid ุงู„ู…ุทู„ูˆุจ ุฅุฐุง ุฃุฎุฐู†ุง ุฃุฑุจุนุฉ

319
00:31:44,900 --> 00:31:50,240
ุจุฃุฑุจุนุฉ ุจุฃุฑุจุนุฉ ุจูŠุตูŠุฑ ุนู†ุฏูŠ ุฃุฑุจุนุฉ ูˆุณุชูŠู†ุŒ ุดูˆ ุงุณู…ู‡ุŸ

320
00:31:50,240 --> 00:31:56,280
ุฃุฑุจุนุฉ ูˆุณุชูŠู† possibility

321
00:31:56,280 --> 00:32:01,340
ูˆุงู„ุฃุฑุจุนุฉ ูˆุณุชูŠู†ุŒ ุนุดุงู† ูŠู€Calculate ุนุดุฑูŠู† Amino

322
00:32:01,340 --> 00:32:08,630
AcidsุŒ ุฑุงุญ ุชู„ุงุญุธ ุฃู†ู‡ูƒู„ ุฃุญูŠุงู†ู‹ุง ุฃูƒุซุฑ ู…ู† ูƒูˆุฏูˆู† ุฃูƒุซุฑ

323
00:32:08,630 --> 00:32:13,890
ู…ู† ุซู„ุงุซ ู…ู† ุงู„ู€Nucleotides ูˆุฑุง ุจุนุถ ู„ู…ุง ุชุฌูŠุจ ุชุฑุชูŠุจ

324
00:32:13,890 --> 00:32:20,850
ู…ุนูŠู† ุฑูˆุญ ุชุชุฃุดุฑู†ุง ุนู„ู‰ ู†ูˆุน ู…ุนูŠู† ู…ู† ุงู„ู€Amino Acids

325
00:32:20,850 --> 00:32:27,670
ูู‡ุฐุง ุฌุฏูˆู„ ุงู„ู„ูŠ ู‡ู… ุชุฑุชูŠุจ ุงู„ูƒูˆุฏูˆู†ุงุชุŒ ู…ุงุดูŠุŸ ูˆูƒู„ ูˆุงุญุฏ

326
00:32:27,670 --> 00:32:33,570
ุดูˆ ูŠู…ุซู„ ูƒู€Amino Acid ูู…ุซู„ู‹ุง ุฅุฐุง ุฌุจู†ุง ุฅู† ุฃู†ุง ุนู†ุฏูŠ

327
00:32:34,040 --> 00:32:41,240
AAA ุฑุญ ู‡ุฐุง ูŠุนุทูŠู†ุง ุงู„ู€ Lysine ุฅุฐุง AAG ูƒู…ุงู† ุฑุญ

328
00:32:41,240 --> 00:32:48,380
ูŠุนุทูŠู†ุง ุงู„ู€ Lysine ู…ุซู„ุงู‹ ู‡ุฐุง ุงู„ู€ Leucine UUA ุจุนุทูŠู†ุง

329
00:32:48,380 --> 00:32:52,840
ุงู„ู€ Leucine UUG ุจุนุทูŠู†ุง ุงู„ู€ Leucine CUU ุจุนุทูŠู†ุง ุงู„ู€

330
00:32:52,840 --> 00:32:59,740
Leucine ูู‡ูƒ ุชุทู„ุนูˆุง ุนู„ูŠู‡ ุฑุงุญ ุชู„ุงู‚ูŠ ุฅู†ู‡ ุจุงู„ุฃุฎูŠุฑ ู‡ู†ุงูƒ

331
00:32:59,740 --> 00:33:03,480
ุงู„ุนุดุฑูŠู† amino acid ููŠู‡ ูƒู„ ูˆุงุญุฏ ู…ู†ู‡ ุนู„ู‰ ุงู„ุฃู‚ู„ ู„ู‡

332
00:33:04,190 --> 00:33:10,010
Codon ู…ุนูŠู†ุŒ ุซู„ุงุซุฉ ู…ุนูŠู†ุฉ ูˆุฑุง ุจุนุถ ุชุนุทูŠูƒ ุฅูŠุด ู‡ูˆ ุงู„ู€

333
00:33:10,010 --> 00:33:17,030
Amino Acid ุงู„ู„ุงุฒู… ุจุงู„ุฅุถุงูุฉ ู„ุฅุฐุง ุฅู†ุชุจู‡ุช ู‡ู†ุง ููŠ ูƒู…ุงู†

334
00:33:17,030 --> 00:33:22,550
ูˆุงุญุฏ ุงุณู…ู‡ Stop Codon ูŠุนู†ูŠ ุนุจุงุฑุฉ ุนู† ุฅุดูŠ ุฅุฐุง ุงู„ู€

335
00:33:22,550 --> 00:33:28,030
Mechanism ุชุจุน ุงู„ู‚ุฑุงุกุฉ ุดุงูู‡ุง ยซUAAยป ู…ุนู†ุงู‡ ุชู€Stop

336
00:33:28,030 --> 00:33:34,720
ยซUAGยป ู…ุนู†ุงู‡ ุชู€Stop ยซUGAยป ุจุฑุถู‡ StopูˆููŠู‡ ู…ูุฑูˆุถ ูˆุงุญุฏุฉ

337
00:33:34,720 --> 00:33:42,020
ุชูƒูˆู† StartุŒ ู…ุงุดูŠุŒ ุจุญุงูˆู„ ุฃุทู„ุน ุนู„ูŠู‡ุง ุจุณ ุดูƒู„ู‡ุง ุตุนุจ ุฃูˆ

338
00:33:42,020 --> 00:33:49,960
ู…ุงู†ูŠุด ุดุงูŠูู‡ุงุŒ ูููŠู‡ ุงู„ .. ุงู„ .. ูŠุนู†ูŠ ู„ุงุฒู… ูŠูƒูˆู† ููŠู‡

339
00:33:49,960 --> 00:33:53,400
startup

340
00:33:53,400 --> 00:34:00,320
codonุŒ ูŠุนู†ูŠ StartุŒ ูˆููŠู‡ ุฅุดูŠ ู„ู„ StopุŒ ุญุชู‰ ุงู„ู€ ยซAOGยป

341
00:34:00,320 --> 00:34:06,530
ูŠุง ุฏูƒุชูˆุฑุŒ ุงู„ู€ Start Codonุนุงุฏุฉู‹ ุจุชูƒูˆู†ุŒ ุนุงุฏุฉู‹ ุจุชูƒูˆู†ุŒ

342
00:34:06,530 --> 00:34:12,510
ุฃู‡ุŒ ู…ุด ุดุงูŠูุฉ ุจุงู„ุฌุฏูˆู„ ุงู„ู„ูŠ ุญุงุทูŠู†ู‡ุŒ ู…ุงุดูŠุŒ ูุงู„ู…ู‡ู…ุŒ

343
00:34:12,510 --> 00:34:15,690
ู…ูˆุฌูˆุฏุŒ ู…ูˆุฌูˆุฏุŒ ู…ูˆุฌูˆุฏ ู…ุน ุงู„ู€ุŒ ู…ุน ูˆุฌูˆุฏ ู‚ุจุงู„

344
00:34:15,690 --> 00:34:23,430
ุงู„ู…ุซูŠูˆู†ูŠู†ุŒ ุฃู‡ุŒ ุงู„ู…ู‡ู…ุŒ ูŠุนู†ูŠ ุงู„ููƒุฑุฉ ุฃู†ู‡ ุงู„ู„ูŠ ู„ู…ุง

345
00:34:23,430 --> 00:34:28,860
ู†ูŠุฌูŠ ู†ู‚ุฑุฃุŒ ุงู„ู„ูŠ ู„ู…ุง ู†ุนู…ู„ ุจู†ุณู…ูŠู‡ุงู„ู€... ู†ู‚ุฑุฃ ุงู„ู€...

346
00:34:28,860 --> 00:34:33,880
ุงู„ู€Nucleotides ุชุจุนุงุช ุงู„ู€DNA ู„ู‚ุทุน ุงู„ู€DNA ููŠ ุงู„ู€Gene

347
00:34:33,880 --> 00:34:36,620
ุฃูˆ ููŠ ุบูŠุฑู‡ ุฃูˆ Whole Genome Sequence ู†ุณู…ูŠู‡ุง

348
00:34:36,620 --> 00:34:42,480
Sequencing ุจุฏูŠ ุฃู†ุชุจุงู‡ ุฅู†ู‡ ูƒู„ ุซู„ุงุซุฉ ุฑุงุญ ูŠุนุทูŠู†ุง

349
00:34:42,480 --> 00:34:47,520
ู…ู‚ุงุจู„ู‡ุง Amino Acid ูู‡ู†ุง ูŠุนู†ูŠ ููŠู‡ ุธูˆุงู‡ุฑ ูƒุชูŠุฑุฉ ุฑุงุญ

350
00:34:47,520 --> 00:34:52,880
ุชุชู…ู†ูŠ ุฅุญู†ุง ุงู„ู„ูŠ ุงุชูƒู„ู…ู†ุง ุงู„ู…ุฑุฉ ุงู„ู„ูŠ ูุงุชุช ุนู„ู‰ ู‚ุถูŠุฉ

351
00:34:52,880 --> 00:35:03,430
ุฅู†ู‡ ุงู„ู€ุนู„ู‰ ู‚ุถูŠุฉ ุฅู†ู‡ ุฃุญูŠุงู†ู‹ุง ู„ูˆ ููŠู‡ ND-SNP ุงู„ู„ูŠ ู‡ูˆ

352
00:35:03,430 --> 00:35:07,530
ุงู„ู€ Single Nucleotide Polymorphism ุฃุญูŠุงู†ู‹ุง ู…ุงู„ู‡ุงุด

353
00:35:07,530 --> 00:35:13,590
ู‚ูŠู…ุฉ ูŠุนู†ูŠุŒ OkayุŒ ููŠู‡ ุงุฎุชู„ุงู ุจูŠู† ุชุฑุชูŠุจ ุงู„ู€

354
00:35:13,590 --> 00:35:20,010
Nucleotides ููŠ ุฌูŠู† ู…ุนูŠู† ููŠ ู‚ุฑุงูŠุชู‡ุง ููŠ ุญุงู„ุฉ ู…ุนูŠู†ุฉ

355
00:35:20,010 --> 00:35:25,430
ุจูŠู† ุดุฎุต ูˆุดุฎุต ุชุงู†ูŠูˆุจุณ ู‡ุงูŠ ุจุงู„ุฃุฎูŠุฑ ุนู„ู‰ ู…ุณุชูˆู‰ ูˆุธูŠููŠ

356
00:35:25,430 --> 00:35:29,970
ุนู„ู‰ ู…ุณุชูˆู‰ ุดูƒู„ ุงู„ุจุฑูˆุชูŠู† ุนู„ู‰ ุดูƒู„ ูˆุธูŠูุฉ ุงู„ุจุฑูˆุชูŠู†

357
00:35:29,970 --> 00:35:39,030
ุจุนุฏูŠู† ู‚ุฏ ู„ุง ูŠูƒูˆู† ู‡ู†ุงูƒ ู‚ูŠู…ุฉ ูƒุซูŠุฑุฉ ูุฅุฐุง ุงูุชุฑุถู†ุง ู‡ุฐู‡

358
00:35:39,030 --> 00:35:43,670
ู…ูˆุฌูˆุฏุฉ ู‡ู†ุง ุงู„ู€ ATG ู…ุซู„ุงู‹ ุงุนุชุจุฑู†ุงู‡ุง Start Codon

359
00:35:43,670 --> 00:35:50,480
ุงู„ูˆุงุญุฏ ุจุฏู‡ ูŠู†ุชุจู‡ุŒ ู…ุงุดูŠู‚ุถูŠุฉ ุฅู†ู‡ ุจุงู„ุฃุฎูŠุฑ ุฅุญู†ุง ูƒู„

360
00:35:50,480 --> 00:35:55,380
ุซู„ุงุซุฉ ู†ู‚ุฑุงู‡ู… ู…ุน ุจุนุถ ุฃูƒุจุฑ ูƒุงุฑุซุฉ ุฑุงุญ ุชุตูŠุฑ ููŠ ุฌู‡ุฉ

361
00:35:55,380 --> 00:36:01,140
ูƒู„ู‡ุง ุงู„ู†ุธุงู… ุฅู†ู‡ ู„ูˆ ูˆุงุญุฏ ุฃูˆ ุงุซู†ูŠู† ู†ูŠูƒู„ูŠูˆุชูŠุฒ ูŠุตูŠุฑู‡ู…

362
00:36:01,140 --> 00:36:06,020
ยซDeletionยป ู‡ุฐุง ุฑุงุญ ูŠุฎุจุต ุงู„ุฏู†ูŠุง ูˆูŠุฎุฑุจุท ุงู„ุฏู†ูŠุง ู„ุฃู†

363
00:36:06,020 --> 00:36:11,440
ูƒู„ ุงู„ู„ูŠ ุจุนุฏู‡ ุฑุงุญ ูŠุตูŠุฑ ุบูŠุฑ ู…ูู‡ูˆู…ุŒ ู…ุงุดูŠุŸ ูู‡ุฐู‡ ุธุงู‡ุฑุฉ

364
00:36:11,440 --> 00:36:15,840
ุจุชุญุฏุซุŒ ูุฅุญู†ุง ู‡ู†ุง ูŠุนู†ูŠ ุฅุฐุง ุงูุชุฑุถู†ุง ู‡ุฐุง ุงู„ู€DNA ุงู„ุฃูˆู„

365
00:36:16,810 --> 00:36:20,410
ุฑุญ ูŠุตูŠุฑ ุนู…ู„ูŠุฉ ุงู„ู€ Transcription ุฑุญ ูŠุทู„ุนู†ูŠ

366
00:36:20,410 --> 00:36:25,930
Messenger RNA ู‡ุฐุง ุจุงู„ุฃูˆู„ ู‚ุงู„ู„ู‡ ุงุจุฏุฃ ู‡ู†ุง ุงู„ู€

367
00:36:25,930 --> 00:36:31,510
Messenger RNA ู‡ูŠู‡ ุงู„ุชุฑุชูŠุจ ุทู„ุน ู…ูƒุงูุฆ ู„ู„ูŠ ู‚ุจู„ ู„ู…ุง

368
00:36:31,510 --> 00:36:36,690
ู†ุนู…ู„ ุนู…ู„ูŠุฉ ุงู„ู€ Translation ุจุชุตูŠุฑ ู„ุงุฒู… ุชูƒูˆู† ุซู„ุงุซูŠุงุช

369
00:36:36,690 --> 00:36:43,520
ูู…ู† ุฃูˆู„ ู…ุง ุจูŠุจุฏุฃ ูƒู„ ุซู„ุงุซุฉ ุจู†ุตูŠุฑ ูŠู†ู‚ุฑู†ูŠุนู†ูŠ ู‡ูˆ ุฃู†ุง

370
00:36:43,520 --> 00:36:49,200
ุฃุธู† ุจุงู„ูŠู†ุŒ ู‡ุณุชูŠู†ุŒ ู„ูˆุณูŠู†ุŒ ุซุฑูˆู†ูŠู†ุŒ ุจุฑูˆู„ูŠู†ุŒ ุฌู„ูŠุณูŠู†ุŒ

371
00:36:49,200 --> 00:36:54,060
ูƒุฐุงุŒ ูุจุตูŠุฑ ุงู„ู€ TranscriptionุŒ ุงู„ู€ Translation ุงู„ู„ูŠ

372
00:36:54,060 --> 00:36:58,420
ุจุนุทูŠู†ุง ุงู„ุจุฑูˆุชูŠู† ุงู„ู„ูŠ ุฑุงุญ ุฃุดูˆูู‡ ุญุณุจ ุงู„ุชุฑุชูŠุจ ูุงู„ู„ูŠ

373
00:36:58,420 --> 00:37:04,360
ุจุชุญูƒู… ุจุชุฑุชูŠุจ ุดูƒู„ ุงู„ู€ Amino Acids ููŠ ุงู„ุจุฑูˆุชูŠู† ู‡ูˆ

374
00:37:04,360 --> 00:37:10,000
ุชุฑุชูŠุจ ุงู„ู€ Nucleotides ููŠ ุงู„ู€ DNA ูƒู„ Amino Acid ู‡ูˆ

375
00:37:10,000 --> 00:37:18,240
ู†ุชูŠุฌุฉ ุซู„ุงุซุฉูˆุฑุง ุจุนุถ ุงุณู…ู‡ู… Codon ู…ู† ุงู„ู€ ยซDNAยป ุฃูˆ ุงู„ู€

376
00:37:18,240 --> 00:37:24,800
ยซRNAยป ุงู„ู…ูƒุงูุฆู„ู‡ ุจู†ุณู…ูŠู‡ Reading Frame ูŠุนู†ูŠ ุงู„ู‚ุทุน

377
00:37:24,800 --> 00:37:29,880
ุงู„ู„ูŠ ุจู†ู‚ุฑุงู‡ุง ู‡ุฐู‡ ุถุฑูˆุฑูŠุฉ ุชูƒูˆู† ู…ุธุจูˆุทุฉ ุชู…ุงู…ุงู‹ ุญุชู‰

378
00:37:29,880 --> 00:37:34,140
ุชุทู„ุน ุงู„ู‚ุฑุงุกุฉ ุณู„ูŠู…ุฉ ุบูŠุฑ ู‡ูŠูƒ ุฑุงุญ ูŠุทู„ุน ุฅุดูŠ ู…ุงู„ูˆุด ู…ุนู†ู‰

379
00:37:34,140 --> 00:37:35,960
ูŠุนู†ูŠ ููŠ ุงุณู„ุฉ

380
00:37:41,180 --> 00:37:47,200
ุงู„ุขู† ู‡ุฐู‡ ู…ุฑุฉ ุซุงู†ูŠุฉ ู…ูˆุถูˆุน ุฅู†ู‡ ุฃู†ุง ุฃุญูŠุงู†ู‹ุง ุจูƒูˆู† ููŠ

381
00:37:47,200 --> 00:37:52,840
ุนู†ุฏู‰ Exons ุงู„ู„ูŠ ู‡ู… ุงู„ู…ู†ุทู‚ุฉ ุงู„ู„ูŠ ูŠุชู… ุงู„ุงุณุชูุงุฏุฉ ู…ู†ู‡ุง

382
00:37:52,840 --> 00:37:56,480
ูˆ ุงู„ุชุนุงู…ู„ ู…ุนู‡ุง ูˆู‡ูŠ ุงู„ู„ูŠ ุจุฏู†ุง ุฅูŠุงู‡ุง ูˆููŠ Introns

383
00:37:56,480 --> 00:38:03,680
ุงู„ู„ูŠ ู‡ู… ู…ุง ู„ู‡ูˆู…ุด ู…ุนู†ู‰ ู‡ุฐูˆู„ุฉ ูŠุนู†ูŠ ู†ุธุฑูŠู‹ุง ูŠุชู… ู‚ุตู‡ู… ูˆ

384
00:38:03,680 --> 00:38:09,820
ุงู„ุชุฎู„ุต ู…ู†ู‡ู… ูุงุญู†ุง ู†ุญูƒูŠ ุจุนุฏ ุดูˆูŠุฉุฅู†ู‡ ุงู„ู€ ยซnonยป

385
00:38:09,820 --> 00:38:16,000
ุจูŠุณู…ูˆู‡ ูŠุนู†ูŠ ยซnon-coding RNAยป ู…ุงุดูŠ ุงู„ู€ ยซDNAยป ู„ู…ุง

386
00:38:16,000 --> 00:38:21,020
ุญูƒูŠู†ุง ยซnon-codingยป ูƒู†ุง ู†ู‚ูˆู„ ูŠุนู†ูŠ ุจูู‡ู…ู‡ุง ุนู„ู‰ ู…ุณุชูˆูŠู†

387
00:38:21,020 --> 00:38:29,120
ุงู„ู„ูŠ ู‡ูŠ ุฅู†ู‡ ู…ู…ูƒู† ุชูƒูˆู† ยซnon-codingยป ูŠุนู†ูŠ ู†ู‡ุงุฆูŠู‹ุง ู„ุง

388
00:38:29,120 --> 00:38:37,570
ูŠุชู… ู†ุณู‚ู‡ุŒ ู…ุงุดูŠุงู„ู€ L-introns ุจูŠุชู… ู†ุณุฎู‡ุง ุจุณ ุจูŠุชู…

389
00:38:37,570 --> 00:38:42,610
ุงู„ุงุณุชุบู†ุงุก ุนู†ู‡ุง ุจุณ ู…ู…ูƒู† ู‚ุทุน ู…ู† ุงู„ู€ DNA ู„ุง ูŠุชู… ู†ุณุฎู‡ุง

390
00:38:42,610 --> 00:38:47,590
ุฃุตู„ุงู‹ ู…ุด ููŠู‡ุง ุจุฏุงูŠุฉ ูˆุฅุจุฏุฃ ู‡ูˆู† ูˆPromote ุงู„ region

391
00:38:47,590 --> 00:38:51,770
ูˆุฃุดูŠุงุก ุญุชู‰ ุชุชุญูƒู… ููŠู‡ุง ูููŠ ุฃุดูŠุงุก ู„ุง ูŠุชู… ู†ุณุฎู‡ุง

392
00:38:51,770 --> 00:38:58,930
ู†ู‡ุงุฆูŠุงู‹ ูู‡ุฐุง ุจู†ุนุชุจุฑู‡ Non-coding ุงู„ู€ DNAูˆููŠ ุงู„ู€ RNA

393
00:38:58,930 --> 00:39:04,610
ุงู„ู„ูŠ ุฑุงุญ ูŠุทู„ุน ุจุงู„ู†ุณุจุฉ ู„ู„ุขู† ูƒู€ Intron ู‡ูˆ Non-coding

394
00:39:04,610 --> 00:39:09,830
ูุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ู€ RNA ุงู„ู€ ExonsุŒ ู‡ู†ุง ุซู„ุงุซุฉ ููŠ ู‡ุฐุง

395
00:39:09,830 --> 00:39:17,270
ุงู„ุจุฑูˆุชูŠู† ุงู„ู€ Exons ู‡ู… ุงู„ู€ Coded ุจุญูŠุซ ุฃู†ู‡ ูŠุชู…

396
00:39:17,270 --> 00:39:22,010
ุงุณุชูุงุฏุฉ ู…ู† ุงู„ู€ RNA ุชุจุนู‡ู… ููŠ ุนู…ู„ ุงู„ุจุฑูˆุชูŠู† ูˆุงู„ู€

397
00:39:22,010 --> 00:39:27,810
Introns ู‡ูˆ Non-coding RNA ุงู„ู„ูŠ ุฑุงุญ ูŠุทู„ุนุŒ ู…ุงุดูŠุŸูู‡ุฐู‡

398
00:39:27,810 --> 00:39:32,750
ุฏุฑุฌุฉ ู…ู† ุงู„ุชุนู‚ูŠุฏ ูˆู…ู† ุงู„ุทูˆุงู‡ุฑ ุงู„ู„ูŠ ู…ูˆุฌูˆุฏุฉ ูˆโ€ฆ ู„ู…ุง

399
00:39:32,750 --> 00:39:39,670
ู†ูŠุฌูŠ ู†ุฏุฑุณ ุฃูŠ ุญุงู„ุฉุŒ ุฃูŠ ู…ุฑุถุŒ ุฃูŠ ุฎู„ูŠุฉุŒ ุฃูŠ ุฌุฒุก ู…ู† ุฌุณู…

400
00:39:39,670 --> 00:39:44,670
ุงู„ุฅู†ุณุงู† ู…ู† ู†ุงุญูŠุฉ ูˆุฑุงุซูŠุฉุŒ ููŠู‡ ุณุฑุทุงู† ู…ุนูŠู†ุŒ ููŠู‡ ู…ุฑุถ

401
00:39:44,670 --> 00:39:50,970
ู…ุนูŠู†ุŒ ู†ุชุนุงู…ู„ ู…ุน ู‡ุฐู‡ ุงู„ู…ูุงู‡ูŠู…ุŒ ู…ุงุดูŠุŸ ุฅู†ู‡ู„ู…ู‘ุง ุจุฏูŠ

402
00:39:50,970 --> 00:39:55,050
ุฃุตู ุฃู†ุงุŒ ูˆุดูˆ ุงู„ู„ูŠ ู…ูˆุฌูˆุฏ ุนู†ุฏู‡ู…ุŸ ูˆู„ูŠุด ุตุงุฑ ุงู„ู…ุฑุถุŸ ูˆุดูˆ

403
00:39:55,050 --> 00:39:59,130
ุงู„ุงุฎุชู„ุงู„ุŸ ู„ุฃู† ุทุจุนุงู‹ ุจุงู„ุฃูˆู„ ุจุฏูŠ ุฃูู‡ู… ูƒูŠู ุงู„ุทุจูŠุนูŠ

404
00:39:59,130 --> 00:40:06,570
ูˆูƒูŠู ุงู„ุฅู†ุณุงู† ุงู„ุฃุตู„ูŠ ุฃู…ูˆุฑู‡ ุณุงู„ูƒุฉ ูˆู…ุงุดูŠุŒ ู…ุงุดูŠุŒ ู„ุฃู†

405
00:40:06,570 --> 00:40:10,090
ุงู„ู€ุŒ

406
00:40:10,090 --> 00:40:18,350
ุญุณุงุŒ ุงู„ูƒุชุงุจูƒู… ุฏุฎู„ ููŠ ุงู„ู…ุฑุญู„ุฉ ู‡ุฐู‡ ุธุงู‡ุฑุฉ ู…ู‡ู…ุฉ ุฌุฏุงุŒ

407
00:40:18,350 --> 00:40:27,210
ุจุชุญุงูˆู„ ุชูุณุฑู„ูŠุด ุฃูˆ ูƒูŠู ู†ุชุญูƒู… ุจุงู„ู€ Expression ุชุจุน

408
00:40:27,210 --> 00:40:32,030
ุงู„ู€GeneุŸ ูŠุนู†ูŠ ุฅุญู†ุง ููŠ ุฌุณู… ุงู„ุฅู†ุณุงู† ููŠู‡ ู…ู„ูŠุงุฑุงุช

409
00:40:32,030 --> 00:40:40,290
ุงู„ุฎู„ุงูŠุง ูŠุนู†ูŠ ุนุฏุฏ ู…ู‡ูˆู„ ู„ู…ุง ุชูŠุฌูŠ ุชุฃุฎุฐ ุนุดุฑุฉ ุฃูˆ ูƒุณุงู…ุŒ

410
00:40:40,290 --> 00:40:46,370
ุณุชูŠู† ู…ุฑุฉ ุฃูˆ ุฎู…ุณูŠู† ู…ุฑุฉ ู„ู…ุง ุชูŠุฌูŠ ุชุถุฑุจ ุงู„ุชูˆุงูู‚

411
00:40:46,370 --> 00:40:51,500
ูˆุงู„ุชูˆุจุฉ ุฏูŠุŒ ุฅุญู†ุง ุจุงู„ู…ู„ูŠุงุฑุงุชูƒูŠู ูƒู„ ุฎู„ูŠุฉ ุจุชู‡ุชุฏูŠุŸ ุดูˆ

412
00:40:51,500 --> 00:41:00,960
ุงู„ุฌูŠู†ุงุช ุงู„ู„ูŠ ู‡ูŠ ู„ุงุฒู… ุชุนู…ู„ู‡ุงุŸ ู„ูˆ ุณุฃู„ุชูƒู… ุณุคุงู„ ุงู„ุฌู†ูŠู†

413
00:41:00,960 --> 00:41:05,960
ูƒูŠู ุจุชู†ูุณุŸ ูƒูŠู ุจุงุฎุฏ ุงู„ุฃูƒุณุฌูŠู† ู…ู† ุงู„ุฃู…ุŸ ููŠ ุญุฏ ุจูŠู‚ุฏุฑ

414
00:41:05,960 --> 00:41:11,140
ูŠูุณุฑู„ูŠ ู„ูŠุด ููŠ ุงู„ู€Machine ุงู„ุทูู„ ุฃูˆ ุงู„ุฌู†ูŠู† ุจุงุฎุฏ

415
00:41:11,140 --> 00:41:14,980
ุฃูƒุณุฌูŠู† ุงู„ุฃู…ุŸ ู…ูŠู† ุจุนุฑูุŸ

416
00:41:20,240 --> 00:41:24,380
ุฃู†ุง ุขุณู ุฅุฐุง ุจุฏูŠ ุฃุณู…ุน ู…ู†ูƒู…ุŒ ูŠุนู†ูŠ ูŠุง ุฏูƒุชูˆุฑ ุฃุญู…ุฏ ู„ูˆ

417
00:41:24,380 --> 00:41:30,940
ููŠ ุญุฏ ุจูŠู‚ุฏุฑ ูŠุฌุงูˆุจ ุฃูˆ ูŠุนู†ูŠ ููŠ ุญุฏ ุนู†ุฏู‡ ู…ุนุฑูุฉ ุฃูˆ

418
00:41:30,940 --> 00:41:31,520
ุงู‚ุชุฑุงุญ

419
00:41:37,230 --> 00:41:41,670
ุงู„ุณุคุงู„ ูŠุนู†ูŠ ุงู†ุณู…ุนุŒ ุจุณ ููŠ ุณุคุงู„ ุจุฑุถู‡ ู…ู† ุฏูƒุชูˆุฑุฉ ุจุณู…ุฉ

420
00:41:41,670 --> 00:41:46,930
ู‚ุจู„ ู…ุด ุนุงุฑูู‡ ุงู„ุณุคุงู„ุŒ ุจุชุณุฃู„ ูŠุนู†ูŠ ุงู„ู€Intron ู…ู†

421
00:41:46,930 --> 00:41:50,170
ุงู„ู€Non-coding RNA ูŠุนู†ูŠ ู‡ูŠ ุณุคุงู„ู‡ุง ุฅู†ู‡ ู‡ู„ ู‡ูˆ ู…ูˆุฌูˆุฏ

422
00:41:50,170 --> 00:41:53,990
ูˆู„ุง ู„ุฃุŒ ู…ุด ูุงู‡ู… ุงู„ุณุคุงู„ ุฏูƒุชูˆุฑุฉ ุจุณู…ุฉ ู„ุฃุŒ ู‡ูŠ ู„ู…ุง ู†ูŠุฌูŠ

423
00:41:53,990 --> 00:42:00,690
ู†ุชูุฑุฌ ุจุนุฏูŠู†ุŒ ูˆูŠู† ู‡ุฐุง ุงู„ู€IntronุŒ ุญุณุจ ุดูƒู„ู‡ุŒ ุญุณุจ

424
00:42:00,690 --> 00:42:07,920
ุงู„ุฑุณู…ุฉุŒ ู‚ุทุนุฉ RNA ุงู†ู‚ุตุช ูˆุฅู†ู‡ุง ููŠ ุงู„ู†ูˆุงุนู‡ู„ ู‡ูŠ ุชุทู„ุน

425
00:42:07,920 --> 00:42:14,100
ููŠ ุงู„ู€ CytoplasmุŸ ุฃูƒูŠุฏุŒ ุฃุชูˆู‚ุน ุฐู„ูƒุŒ ุจุณ ุฃู†ุง ุงู„ู„ูŠ

426
00:42:14,100 --> 00:42:18,160
ุจุนุฑูู‡ ู…ู† ุฏุฑุงุณุงุช ุฃุฎุฑู‰ ูˆู…ู† ุฃุดูŠุงุก ุฃุญู†ุง ุฏุฑุณู†ุงู‡ุง ุงู„ู„ูŠ

427
00:42:18,160 --> 00:42:23,440
ู‡ูˆ ุจูŠุณู…ูˆู‡ุง ุงู„ู€ Micro RNAs ุงู„ู„ูŠ ููŠ ุงู„ู€ SerumุŒ ูŠุนู†ูŠ

428
00:42:23,440 --> 00:42:30,020
ุญุชู‰ ุจุฑุง ุงู„ุฎู„ุงูŠุง ุชู…ุงู…ู‹ุงุŒ ุฃุณู‡ ู‡ูˆ ุดูŠุก ู…ูˆุฌูˆุฏุŒ ู…ุงุดูŠุŸ

429
00:42:30,020 --> 00:42:37,850
ูŠุนู†ูŠ ู†ุชูŠุฌุฉ ุชูƒูˆู† ุงู„ู€ Messenger RNAูˆู†ุฌุงุญู‡ ูˆุฎุฑูˆุฌู‡ ู…ู†

430
00:42:37,850 --> 00:42:44,290
ุงู„ู†ูˆุงุก ุฃูˆ ุชูƒูˆู†ู‡ ููŠ ู‚ุทุน ุฅุถุงููŠุฉ ูุฃุญูŠุงู†ู‹ุง ูƒุซูŠุฑุฉ ู‡ุฐู‡

431
00:42:44,290 --> 00:42:48,130
ุงู„ู‚ุทุน ุงู„ุฅุถุงููŠุฉ ูŠู…ูƒู† ุฅู„ู‡ุง ุฃุฏูˆุงุฑุŒ ูŠู…ูƒู† ุฅู„ู‡ุง ู‡ู…ูŠุฉ

432
00:42:48,130 --> 00:42:55,690
ูุฃู†ุง ุงู„ู„ูŠ ุจุญูƒูŠู‡ ุฃู†ุง ู…ุชุฃูƒุฏ ู…ู† ุฃู†ู‡ ู‡ูˆ ูŠูุนุชุจุฑ ู…ู†

433
00:42:55,690 --> 00:43:00,270
ุงู„ุธูˆุงู‡ุฑ ุงู„ู„ูŠ ูŠุชู… ุฏุฑุงุณุชู‡ุง ููŠ ุงู„ุชุณุจุจ ููŠ ุจุนุถ ุงู„ุฃู…ุฑุงุถ

434
00:43:00,270 --> 00:43:08,860
ูŠุนู†ูŠ ุจู‚ูŠุณู‡ ู‚ุฏุงุด ุฃุทูˆุงู„ู‡ุงูˆูƒู…ูŠูŠุชู‡ุง ุญุฌู… ู…ุนูŠู† ูƒุซูŠุฑ ู‚ู„ูŠู„

435
00:43:08,860 --> 00:43:14,660
ูˆุจุชูˆุตู„ ุฅู†ู‡ุง ู…ูˆุฌูˆุฏุฉ ููŠ ุงู„ู€ Serum ูŠุนู†ูŠ ู†ุณุญุจู‡ุง ู…ู† ุฏู…

436
00:43:14,660 --> 00:43:19,280
ุงู„ู…ุฑูŠุถ ูˆู†ูุญุต ุนู„ูŠู‡ุง ุงู„ู„ูŠ ู‡ูŠ ุงู„ู€ Micro RNA ุดุบู„ ุตุนุจ

437
00:43:19,280 --> 00:43:25,220
ู…ุด ุณู‡ู„ ูˆุฅู† ุงู„ูˆุงุญุฏ ูŠู‚ูŠู…ู‡ุง ุจุณ ู‡ุฐู‡ ุงู„ุธุงู‡ุฑุฉ ู‡ูŠ ุธุงู‡ุฑุฉ

438
00:43:25,220 --> 00:43:32,960
ุชุญุฏุซุŒ ู…ูˆุฌูˆุฏุฉุŒ ุดูˆ ุฏูˆุฑู‡ุงุŸ ุฎู„ู‘ูŠู†ุง ุงู„ุขู† ู†ุชูู‚ ุนู„ู‰ ู…ุจุฏุฃ

439
00:43:33,380 --> 00:43:42,200
ุฅู†ู‡ ู‚ุฏ ุชูƒูˆู† ู…ู† ุขู„ูŠุงุช ุงู„ุชุญูƒู… ููŠ ุชุดุบูŠู„ ุงู„ุฌูŠู†ุงุชุŒ ยซู„ูŠุด

440
00:43:42,200 --> 00:43:46,000
ู‡ุฐุง ุงู„ุฌูŠู† ุจูŠุดุชุบู„ุŸยป ยซู„ูŠุด ู‡ุฐุง ุงู„ุฌูŠู† ูƒุงู…ู„ุŸยป ยซู„ูŠุด ู‡ุฐุง

441
00:43:46,000 --> 00:43:50,100
ุงู„ุฌูŠู† ุงุดุชุบู„ 50%ุŸยป ยซู„ูŠุด ู‡ุฐุง ุงู„ุฌูŠู† ุงุดุชุบู„ 90%ุŸยป ยซู„ูŠุด

442
00:43:50,100 --> 00:43:55,720
ู‡ุฐุง ุงู„ุฌูŠู† ุงุดุชุบู„ 10%ุŸยป ูŠุนู†ูŠ ุธูˆุงู‡ุฑ ุฒูŠ ู‡ูŠูƒ ุณุคุงู„ูƒ ุจุฑุฌุน

443
00:43:55,720 --> 00:44:00,940
ู…ุฑุฉ ุซุงู†ูŠุฉ ุงู„ุขู† ุงู„ุฅู†ุณุงู† ุงู„ุทุจูŠุนูŠ ุงู„ู€Hemoglobin ุงู„ู„ูŠ

444
00:44:00,940 --> 00:44:07,520
ููŠ ุฏู…ู‡ ุนู†ุฏูŠุนู†ูŠ ููŠ ุงู„ุญูŠุงุฉ ู‡ูˆ ุจู†ุณู…ูŠู‡ Hemoglobin A1

445
00:44:07,520 --> 00:44:13,000
ูˆA2 ู‡ุฏูˆู„ุฉ ุงู„ู„ูŠ ู…ูˆุฌูˆุฏูŠู†ุŒ ู‡ุฏูˆู„ุฉ ุงู„ู„ูŠ ุจูŠููŠุฏูˆู†ู‡ ุงู„ุฌู†ูŠู†

446
00:44:13,000 --> 00:44:17,880
ููŠ ุจุทู† ุฃู…ู‡ ู…ุง ุจูŠููŠุฏู‡ ูŠูƒูˆู† ุนู†ุฏู‡ ู…ู† ู†ูุณ ู‡ุฐุง ุงู„ู†ูˆุน ู…ู†

447
00:44:17,880 --> 00:44:24,480
ุงู„ู€ Hemoglobin ูุฑุจู†ุง ุจูŠุฌุนู„ ููŠ ุงู„ุฌู†ูŠู† ููŠ ู…ุฑุญู„ุฉ ุงู„ู€

448
00:44:24,480 --> 00:44:27,820
ู…ุฑุญู„ุฉ ุงู„ุฌู†ูŠู†ูŠุฉ ุงู„ุชุณุนุฉ ุฃุดู‡ุฑ ุงู„ู„ูŠ ูˆุงุญุฏุฉ ููŠ ุจุทู† ุฃู…ู‡

449
00:44:28,320 --> 00:44:32,100
ุฅู†ู‡ ูŠูƒูˆู† ุนู†ุฏู‡ ุฅุดูŠ ุจูŠู‚ูˆู„ูˆู„ู‡ ุงู„ู€S-Hemoglobin F

450
00:44:32,100 --> 00:44:36,980
-HemoglobinุŒ ุงู„ู€S ุชุจุน ุงู„ู€Sickle Cell ูุงู„ู€F

451
00:44:36,980 --> 00:44:39,560
-Hemoglobin ุงู„ู„ูŠ ุจูŠุณู…ูˆู‡ Fetal Hemoglobin ู†ูˆุนูŠุฉ

452
00:44:39,560 --> 00:44:43,180
ู…ุฎุชู„ูุฉ ู…ู† ุงู„ู€Hemoglobin ุจุณ ู‡ูˆ HemoglobinุŒ Okay

453
00:44:43,180 --> 00:44:49,500
ู…ูŠุฒุชู‡ ุฅู† ุงุฑุชุจุงุทู‡ ุจุงู„ู€Oxygen ุฃู‚ูˆู‰ ูู‡ูˆ ุจูŠุณุญุจ

454
00:44:49,500 --> 00:44:56,920
ุงู„ู€Oxygen ู…ู† ุงู„ุฃู… ูุงู„ููƒุฑุฉ ุฅู†ู‡ ุฃู†ุง ููŠ ูƒู„ู†ุงุŒ ู…ุด ุจุณ

455
00:44:56,920 --> 00:45:03,610
ุฃู†ุงุŒ ูƒู„ู†ุงููŠ ู…ุฑุญู„ุฉ ุงู„ุฌู†ูŠู†ูŠุฉ ู…ู† ุญูŠุงุชู†ุง ุจุญุงุฌุฉ ุฅู†ู‡

456
00:45:03,610 --> 00:45:09,470
ู†ูƒูˆู‘ู† Hemoglobin F ูˆู„ูŠุณ Hemoglobin A1 ูˆA2 ุงู„ู„ูŠ

457
00:45:09,470 --> 00:45:13,490
ู…ูˆุฌูˆุฏ ู…ุนุงู†ุง ููŠ ุจุนุฏ ุงู„ุญูŠุงุฉ ูุงู„ู„ูŠ ุจูŠุตูŠุฑ ุจุณ ูŠูˆู„ุฏ

458
00:45:13,490 --> 00:45:17,690
ุงู„ุฅู†ุณุงู† ูˆูŠุชุบูŠุฑ ุงู„ุจูŠุฆุฉ ุงู„ู„ูŠ ู‡ูˆ ููŠู‡ุง ุจูŠุตูŠุฑ ุงู„ุฏุฑูŠู‚ุชูŠู†

459
00:45:17,690 --> 00:45:24,170
ุชุชู†ูุณ ูˆูŠุตูŠุฑ ูŠุฎุชู„ู ุดูˆูŠู‡ ุดูˆูŠู‡ ุงู„ู€Hemoglobin ุจุชุบูŠุฑ

460
00:45:24,750 --> 00:45:29,310
ุงู„ุฌุณู… ุจูŠุจุทู„ ูŠุทู„ุน ุงู„ู€ F- Hemoglobin ูˆูŠุตูŠุฑ ูŠุทู„ุน ุงู„ู€

461
00:45:29,310 --> 00:45:34,830
A1 ูˆุงู„ู€ A2 Hemoglobin ูู‡ุฐู‡ ุธุงู‡ุฑุฉ ูƒูŠู ุฑุจู†ุง ุณูˆู‘ุงู‡ุง

462
00:45:34,830 --> 00:45:41,230
ููŠู†ุงุŒ ู„ูŠุด ุชุชุญุฏุซุŸ ู‡ูŠ ุทุจุนู‹ุง ูˆุงุถุญุฉ ุณุจุจู‡ุง ุฅู†ู‡ ุฃู†ุง ู„ูˆ

463
00:45:41,230 --> 00:45:45,970
ูƒุงู† ุนู†ุฏูŠ ู†ูุณ ุงู„ู‚ูˆุฉ ุชุฌุฐุจ ุงู„ู€ Oxygen ุฒูŠ ุงู„ู€

464
00:45:45,970 --> 00:45:50,170
Hemoglobin ุชุจุน ุงู„ูˆุงู„ุฏ ู…ุนู†ุงุชู‡ ู…ุง ุฑุงุญ ุฃุฎุฏ Oxygen

465
00:45:50,170 --> 00:45:56,820
ู…ู†ู‡ุงุŒ ู…ุง ุฑุงุญ ูŠู†ุชู‚ู„ ุงู„ู€ OxygenูููŠ ู„ุญุธุฉ ู…ุนูŠู†ุฉ ุงู„ู€

466
00:45:56,820 --> 00:46:02,220
Hemoglobin F ู‡ุฐุง ู„ุงุฒู… ู‡ูˆ ุงู„ู„ูŠ ุงู†ุจู†ู‰ ูˆุจุนุฏูŠู† ุจุณ

467
00:46:02,220 --> 00:46:06,540
ู†ูˆู„ุฏุŒ ู‡ุฐุง ุจูŠูˆู‚ูุŒ ุจูŠุตูŠุฑ ุจูŠุทู„ุน ู†ูˆุน ุซุงู†ูŠ ูู‡ุฐู‡ ุงู„ุธูˆุงู‡ุฑ

468
00:46:06,540 --> 00:46:13,500
ุจุชุญุฏุซ ููŠ ุฌุณู… ุงู„ุฅู†ุณุงู† ูƒุชูŠุฑ ูˆูƒู„ ู†ูˆุน ุฎู„ุงูŠุง ุจุชู„ุงู‚ูŠ ููŠู‡

469
00:46:13,500 --> 00:46:18,380
ุฅุดูŠ ู„ุงุฒู… ูŠุชุดุบู„ ูˆููŠู‡ ุฅุดูŠ ู„ุงุฒู… ูŠุชูˆู‚ู ููŠู‡ ุฅุดูŠ ุจุชุดุบู„ุŒ

470
00:46:18,380 --> 00:46:21,500
ููŠู‡ ุฅุดูŠ ุจุชูˆู‚ู ุดูˆ ุงู„ุฃู„ูŠุงุช ุงู„ู„ูŠ ุจุชุชุญูƒู… ููŠ ู‡ุฐุง ุงู„ุฃู…ุฑุŸ

471
00:46:21,910 --> 00:46:25,210
ุงู„ู‚ุงู„ูŠุงุช ุงู„ู„ูŠ ุจุชุชุญูƒู… ููŠู‡ ู‡ูŠ ุงู„ู€ Epigenetic

472
00:46:25,210 --> 00:46:31,330
Mechanisms ุฃุญู†ุง ุฃุณุงู‰ ุจุทู„ู†ุง ู†ุชูƒู„ู… ุดูˆ ุงู„ู€ DNA ู†ูุณู‡

473
00:46:31,330 --> 00:46:37,350
ุนู†ุฏู‡ ุดูˆ ุงู„ู…ุนู„ูˆู… ุงู„ู„ูŠ ููŠู‡ ุฃุญู†ุง ุฃุณุงู‰ ุงู„ู€ ูŠุนู†ูŠ ูƒู„

474
00:46:37,350 --> 00:46:41,230
ุฎู„ุงูŠุง ุงู„ุฌุณู… ุฑุงุญ ูŠูƒูˆู† ููŠู‡ุง ุงู„ู€ Hemoglobin F ูˆ ุงู„ู€

475
00:46:41,230 --> 00:46:48,350
Hemoglobin S ูˆ ุงู„ู€ A1 ูˆ A2 ูƒุฌูŠู† ุขู‡ ูƒู„ู‡ุง ููŠู‡ุง ุงู„ุฌูŠู†

476
00:46:48,350 --> 00:46:55,460
ู‡ุฐุง ูˆุงู„ุฌูŠู†ุงุช ู‡ุฐู‡ุจุณ ููŠ ู…ุฑุญู„ุฉ ู…ุนูŠู†ุฉุŒ ููŠ ุญูŠุงุฉ ู…ุนูŠู†ุฉุŒ

477
00:46:55,460 --> 00:47:01,440
ููŠ ุธุฑู ู…ุนูŠู† ุจูŠุตูŠุฑ ููŠู‡ ุฏุงุนูŠ ู„ุฅูŠุด ู…ุญุฏุฏ ูุจูŠุชู… ุฅู†ุชุงุฌู‡

478
00:47:01,440 --> 00:47:06,160
ุฃูˆ ุจูŠุชู… ุชุดุบูŠู„ู‡ ุฃูˆ ุจูŠุชู…ุŒ ุจูŠู‚ูˆู„ ุณูˆูŠู‹ุง ู„ู…ุง ู†ู‚ูˆู„ ุนู†

479
00:47:06,160 --> 00:47:09,920
ุงู„ู€DNA ุจูŠุตูŠุฑ ุงู„ู€Transcription ุชุจุนู‡ ุนุดุงู† ูŠุนุทูŠู†ุง

480
00:47:09,920 --> 00:47:15,980
ุงู„ู€Messenger RNA ุนุดุงู† ูŠุนุทูŠู†ุง ุงู„ู€Protein ุชุจุนู‡ ุญุชู‰

481
00:47:15,980 --> 00:47:19,740
ุชู‚ุฏุฑ ุงู„ูˆุธูŠูุฉ ุงู„ู…ุทู„ูˆุจุฉ ูู„ู…ุง ุฃู†ุง ุฃุดูˆู ุงู„ู€Protein ุทู„ุน

482
00:47:20,300 --> 00:47:24,360
ู…ุนู†ุงุชู‡ ุงู„ุฌูŠู† ุชุจุนู‡ ุงุดุชุบู„ ุทุจ ู„ูŠุด ุงุดุชุบู„ุŸ ู„ูŠุด ุจุนุฏูŠู†

483
00:47:24,360 --> 00:47:29,460
ูˆู‚ูุŸ ู‡ุฐู‡ ุฏูˆุงู‡ุฑ ุงู„ู€ Epigenetics ุฏูˆุงู‡ุฑ ุงู„ู€

484
00:47:29,460 --> 00:47:37,460
Epigenetics ููŠ ุฌุฒุก ู…ู†ู‡ุง ูŠุนู†ูŠ ุฑุงุญ ู†ุญูƒูŠ ุนู† ููŠู‡

485
00:47:37,460 --> 00:47:46,840
ุงุฎุชู„ุงูุงุช ูˆุชูุงูˆุช ุจูŠู† ูƒู…ูŠุฉ ุงู„ุชุนุฏูŠู„ ุงู„ูƒูŠู…ุงูˆูŠ ุนู„ู‰ ู†ูุณ

486
00:47:46,840 --> 00:47:57,570
ุงู„ู€DNA ุฃูˆ ุงู„ู€Histonesูˆุงู„ู„ูŠ ู‡ูŠ ุจูŠุนุชุจุฑูˆู‡ุง ุงู„ู€

487
00:47:57,570 --> 00:48:02,610
ยซู‡ุณุชูˆู†ยป ูููŠ ุนู†ุฏูŠ ุธุงู‡ุฑุฉ ุงู„ู€ ยซDNA methylationยป ูŠุนู†ูŠ

488
00:48:02,610 --> 00:48:09,870
ุงู„ู€ ยซDNAยป ุจุนุฏ ู…ุง ูƒุงู† ุดูˆ ุงุณู…ู‡ุŸ

489
00:48:09,870 --> 00:48:16,210
ุงู„ู€ ยซDNAยป ุจุนุฏ ู…ุง ูƒุงู† ุจุทุฑูŠู‚ุชู‡ ุงู„ุนุงุฏูŠุฉ ู…ุซู„ู‹ุง ุฃู†ู‡ ููŠ

490
00:48:16,210 --> 00:48:20,150
ู…ูƒุงู† ู…ุนูŠู† ุจูŠุตูŠุฑ ุนู…ู„ูŠุฉ ยซmethylationยปุฃูˆ ุนู„ู‰ ุงู„ู€

491
00:48:20,150 --> 00:48:28,290
Histone ู…ู…ูƒู† ุชูƒูˆู† ููŠู‡ุง Variations ุฃูˆ Glucosylation

492
00:48:28,290 --> 00:48:33,010
ุฃูˆ Methylation ูƒู…ุงู† ู„ู„ู€ Histone ุฃูˆ ุงู„ู€ Histone-T

493
00:48:33,010 --> 00:48:38,450
ูŠุนู†ูŠ ุงู„ู€ Histone ู‡ูˆ ุงู„ู‚ุทุนุฉ

494
00:48:38,450 --> 00:48:44,590
ุงู„ู„ูŠ ุจุชู…ู„ู ุงู„ู€ DNA ุนู„ูŠู‡ุง ุจุดูƒู„ ุฃูƒุจุฑ ุญุชู‰ ูŠุตุบุฑ ุญุฌู…ู‡

495
00:48:44,590 --> 00:48:51,260
ุญุชู‰ ู†ุนุฑู ู†ุฏุฎู„ู‡ ูƒู„ู‡ ุจุงู„ูƒุฑู…ูˆุฒูˆู…ู…ุงุดูŠุŒ ุฅุฐุง ู…ุง ูƒุงู†ุด ููŠู‡

496
00:48:51,260 --> 00:48:59,980
ยซู‡ุณุชูˆู†ยป ูˆยซูƒุฑูˆู…ุงุชูŠุฏยป ุฃูˆ ุงู„ู€โ€ฆ ุงู„ู€โ€ฆ ูŠุนู†ูŠ ุงู„ุฃุดูŠุงุก

497
00:48:59,980 --> 00:49:04,640
ุงู„ุซุงู†ูŠุฉ ุงู„ู„ูŠ ู‡ูŠ ุฅุถุงููŠุฉ ุญุชู‰ ูŠุชู… ุนู…ู„ูŠุฉ ู„ู ุงู„ู€DNA ู…ุง

498
00:49:04,640 --> 00:49:09,000
ุจูŠูƒูˆู† ุจุงู„ุดูƒู„ ุงู„ู„ูŠ ุจูŠุทู„ุน ููŠู‡ ุจุดูƒู„ ู…ุถุบูˆุท ูˆุจุนุฏูŠู† ูŠูƒูˆู†

499
00:49:09,000 --> 00:49:14,140
ู‡ูŠูƒ ู…ุฑุชุจ ูˆูŠูŠุฌูŠ ุฌุงู†ุจ ุจุนุถ ูˆูŠู†ูุตู„ูˆุง ุนู† ุจุนุถ ู„ูˆ ูƒุงู† ููŠู‡

500
00:49:14,140 --> 00:49:20,060
ุงุฎุชู„ุงู„ ููŠ ุงู„ู„ููˆู…ุด ู…ุถุบูˆุท ุจุดูƒู„ ูƒุจูŠุฑ ู…ู…ูƒู† ูŠุฎุฑู‘ุจ

501
00:49:20,060 --> 00:49:25,360
ุงู„ุฏู†ูŠุง ุฅู† ุงู†ูุตุงู„ู‡ุง ู…ุง ูŠูƒูˆู† ุงู†ูุตุงู„ ุณู„ุณ ูˆุณู‡ู„ ู…ุชูƒุงูุฆ

502
00:49:25,360 --> 00:49:33,100
ู…ุธุจูˆุท ุฒูŠ ู…ุง ุจุฏู†ุงูŠุง ูˆุงุถุญุŸ ููŠ ุฃุณุฆู„ุฉุŸ

503
00:49:33,100 --> 00:49:38,920
ููŠ ุฃุณุฆู„ุฉุŸ

504
00:49:38,920 --> 00:49:44,440
ู…ุงุดูŠ ูุงู„ุขู†

505
00:49:45,120 --> 00:49:49,960
ุงู„ุธูˆุงู‡ุฑ ุงู„ู€ Epigenetics ุงู„ู„ูŠ ู‡ูŠ ุญูƒูŠู†ุง ูˆุชูƒู„ู…ู†ุง ุนู†

506
00:49:49,960 --> 00:49:57,060
ุงู„ู€ Micro-RNA ุฃูˆ ุงู„ู€ Non-coding RNA ูˆุฌูˆุฏู‡ ูƒูŠู

507
00:49:57,060 --> 00:50:05,020
ุฃุฏูˆุงุฑู‡ุŒ ุงู„ู€ DNA methylation ุงู„ู€ Histone ุณูˆุงุก Tail

508
00:50:05,020 --> 00:50:09,720
methylation ุฃูˆ Histone variationุŒ ู‡ุฐู‡ ูƒู„ู‡ุง ุธูˆุงู‡ุฑ

509
00:50:09,720 --> 00:50:17,740
ู…ูˆุฌูˆุฏุฉ ูˆุชุดุชุฑูƒููŠ ู‚ุถูŠุฉ ุงู„ุชุญูƒู… ููŠ ุนู…ู„ูŠุฉ ู‚ุฑุงุกุฉ ุงู„ุฌูŠู†ุงุช

510
00:50:17,740 --> 00:50:22,180
ุฃู†ู‡ ุงู„ุฌูŠู† ุงู„ู„ูŠ ูŠุดุชุบู„ ูˆุฃู†ู‡ ุงู„ุฌูŠู† ุงู„ู„ูŠ ูŠุธู„ ุณุงูƒู† ูู‡ุฐู‡

511
00:50:22,180 --> 00:50:27,940
ูƒู„ู‡ุง ุบูˆุงู‡ุฑ ู…ูˆุฌูˆุฏุฉ ูˆุฅู† ุดุงุก ุงู„ู„ู‡ ู„ู…ุง ู†ุฏุฎู„ ุจุนุฏูŠู† ููŠ

512
00:50:27,940 --> 00:50:32,690
ุจุนุถ ุงู„ู…ุญุงุถุฑุงุช ูŠู…ูƒู† ู†ุถุฑุจ ุฃู†ูู„ ุนู„ูŠู‡ู…ุจุณ ุฃู†ุง ุจุธู† ุฅู†ู‡

513
00:50:32,690 --> 00:50:38,430
ู…ู‡ู… ูƒู…ุจุฏุฃ ููƒุฑูŠ ู‡ูŠูƒูŠ ุนู‚ู„ูŠ ุงู„ูˆุงุญุฏ ูŠูƒูˆู† ูุงู‡ู…ู‡ ูˆูŠุณุชูˆุนุจ

514
00:50:38,430 --> 00:50:42,030
ู„ู…ู† ูŠุณู…ุน ู‡ุฐู‡ ุงู„ูƒู„ู…ุฉ ุดูˆ ุงู„ู„ูŠ ู…ูˆุฌูˆุฏ ูˆุดูˆ ุงู„ู„ูŠ ุจุชูƒู„ู…

515
00:50:42,030 --> 00:50:47,590
ุนู†ู‡ุŒ ู‡ุงูŠ ุงู„ู€ Methylation ูุงู„ู€ Cytosine ู…ู…ูƒู† ูŠุชุญูˆู„

516
00:50:47,590 --> 00:50:53,030
ู„ู€ Methylcytosine ูˆFive-Hydroxymethylcytosine ูƒู†ูˆุน

517
00:50:53,030 --> 00:51:03,360
ู…ูˆุฌูˆุฏุฉ ุงู„ุฃุดูŠุงุก ู‡ุฐู‡ ุฃุญูŠุงู†ู‹ุง ุชุชุฏุฎู„ ุฅู†ู‡ู„ู…ู‘ุง ุชู… ู‚ุฑุงุกุฉ

518
00:51:03,360 --> 00:51:12,400
ุฃูˆ ุชุนุงู…ู„ ุงู„ู€ DNA ุจุชู… ุฃุญูŠุงู†ู‹ุง ุงุณุชุฎุฏุงู… ู‡ุฐู‡ ุงู„ุชุฑุงูƒูŠุจ

519
00:51:12,400 --> 00:51:17,640
ููŠ ุฅู†ู‡ ูƒูŠู ูŠู‚ุฑุฃุŒ ูƒูŠูุŒ ู…ู† ูˆูŠู† ู„ูˆูŠู†ุŒ ูƒูŠู ูŠู‚ุฑุฃ ุงู„ู€

520
00:51:17,640 --> 00:51:21,100
Three-dimensional architecture ุงู„ู€ Dynamic

521
00:51:21,100 --> 00:51:23,800
packaging of the genome ุจูŠูˆุถุน Increasing Level of

522
00:51:23,800 --> 00:51:28,530
ResolutionููŠู‡ ู‡ู†ุง ุงู„ู€ Individual Chromosome

523
00:51:28,530 --> 00:51:35,710
Territories ูŠุนู†ูŠ ููŠ ุงู„ู†ูˆุงุฉ ูƒู„ ูƒุฑูˆู…ูˆุฒูˆู… ู‡ูƒูŠ ู„ู ุตุงุฑุช

524
00:51:35,710 --> 00:51:40,110
ู…ุด ู…ุถุบูˆุทุฉ ูƒุซูŠุฑ ุฒูŠ ู…ุง ุจู†ุดูˆูู‡ ุนู†ุฏ ุงู„ู€ Karyotype ููŠ

525
00:51:40,110 --> 00:51:43,910
ุงู„ู€ Cell Division ุจุณ ูƒู„ ูˆุงุญุฏ ุฅู„ู‡ ุฒูŠ ู…ุง ุจูŠู‚ูˆู„ูˆุง ู‡ู†ุง

526
00:51:43,910 --> 00:51:48,870
ู…ุนุชุจุฑูŠู†ู‡ ุฅู„ู‡ ู…ู†ุทู‚ุฉุŒ ุฅู„ู‡ TerritoryูˆุจุนุฏูŠู† ุฃุญูŠุงู†ู‹ุง

527
00:51:48,870 --> 00:51:53,830
ุจุชูุงุนู„ูˆุง ู…ุน ุจุนุถ ุจุณ ููŠ ุงู„ุฃุฎูŠุฑ ู„ู…ุง ุจุฏู†ุง ู†ูŠุฌูŠ ู†ู‚ุฑุฃ

528
00:51:53,830 --> 00:52:00,890
ุฅุดูŠ ุจุฏู‡ ุงู„ู€ Promoter Region ุชุจุฏุฃ ุชุดุชุบู„ ูˆูŠุชู… ุชุญููŠุฒ

529
00:52:00,890 --> 00:52:06,010
ุงู„ู‚ู„ูŠุงุช ู†ุณู‚ ุงู„ู€ DNA ุฃูˆ ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€ Transcription

530
00:52:06,010 --> 00:52:09,510
ู„ู„ู€ DNA ูˆุฃุญูŠุงู†ู‹ุงุŒ ูŠุนู†ูŠ ู‡ูˆู† ุงู„ุธุงู‡ุฑุฉ ุงู„ู„ูŠ ุจุฏูŠูˆุง

531
00:52:09,510 --> 00:52:14,310
ูŠุญูƒูˆู‡ุง ุฃู†ู‡ ุฃุตู„ ุฃู† ุงู„ู€ Promoter Region ุฅุญู†ุง ู†ูƒูˆู†

532
00:52:14,310 --> 00:52:22,110
ู‚ุจู„ุงู„ู€ Coding Gene Segment ู…ุจุงุดุฑุฉ ุจุณ ุฃุญูŠุงู†ู‹ุง ููŠู‡

533
00:52:22,110 --> 00:52:27,790
Promoter Areas ุฃูˆ Promoter Regions ุจุชูƒูˆู† ุฃุจุนุฏ

534
00:52:27,790 --> 00:52:34,210
ุจูƒุชูŠุฑ ุจุณ ู†ุชูŠุฌุฉ ุงู„ุญุจู„ ุงู„ุทูˆูŠู„ ู…ู…ูƒู† ูŠูƒูˆู†ูˆุง ุฌู†ุจ ุจุนุถ ููŠ

535
00:52:34,210 --> 00:52:42,210
ู„ุญุธุฉ ู…ุนูŠู†ุฉ ุจุญูŠุซ ุฃู† ู‡ุฐุง ูŠุณุงุนุฏ ุนู„ู‰ ุฃู†ู‡ ู‚ู„ูŠู„ุฉ ุงู„ุชุญูƒู…

536
00:52:42,210 --> 00:52:47,800
ุฃู†ู‡ ูˆูŠู† ุชุจุฏุฃ ููŠ ุงู„ู‚ุฑุงุกุฉู…ุงุดูŠุŒ ู…ู† ูˆูŠู† ุฃุจุฏุฃ ููŠ ุงู„ู€DNA

537
00:52:47,800 --> 00:52:55,540
ุงู„ู„ุงุฒู…ุŸ ูู‡ุฐู‡ ู‚ุทุน ูˆุธูˆุงู‡ุฑ ุจุชุญุฏุซ ุงู„ุขู†

538
00:52:55,540 --> 00:53:03,200
ุฃู†ุง ู‡ุฐุง ุงู„ู…ูˆุถูˆุน ุฃุชูˆู‚ูู†ุง ุนู†ุฏู‡ ุงู„ู…ุฑุฉ ุงู„ู„ูŠ ูุงุชุช ูˆูŠุนู†ูŠ

539
00:53:03,200 --> 00:53:14,060
ุฎู„ู‘ูŠู†ุง ู†ูู‡ู…ู‡ ู…ู† ุฎู„ุงู„ ุฃู…ุซู„ุฉู†ูุชุฑุถ ุฃู†ุง ุจุฏูŠ ุฃุฏุฑุณ ุงู„ู€

540
00:53:14,060 --> 00:53:18,080
ยซุฌูŠู†ยปุŒ ููŠ ุฃุณุฆู„ุฉุŸ

541
00:53:18,080 --> 00:53:22,500
ุฏูƒุชูˆุฑ ุฃุญู…ุฏุŒ ููŠ ุฅูŠุด ุฃุณุฆู„ุฉุŸ ุชู‚ุฑูŠุจู‹ุง ู„ุญุฏ ุงู„ุขู†ุŒ ู„ุฃ

542
00:53:22,500 --> 00:53:29,560
ุทูŠุจุŒ ุฃุณุณุง ู†ูุชุฑุถ ุฃู†ุง ุจุฏุฑุณ ุงู„ู€ ยซABO System Blood

543
00:53:29,560 --> 00:53:37,800
Groupยป ููŠู‡ ู‚ู„ูŠู„ุŒ ููŠู‡ ู…ูƒุงู†ุŒ ูˆุฅู„ูŠ ุฃูƒุซุฑ ู…ู† ุฎูŠุงุฑุŒ

544
00:53:37,800 --> 00:53:42,840
ู…ุงุดูŠุŸุฃู†ุง ุงู„ู€ Blood Group ุงู„ู€ Inheritance ุชุจุนุชู‡ุง

545
00:53:42,840 --> 00:53:47,440
ุงู„ู€ ABO System ูˆู…ูู‡ูˆู… ุดูˆู‡ูŠู‡ ูˆุงู„ู„ูŠ ุฏู‡ ุจู†ุฏุฎู„ ููŠู‡ุง

546
00:53:47,440 --> 00:53:54,000
ุชูุงุตูŠู„ุฉ ุจุนุฏูŠู† ุจูŠุตูŠุฑ ุจุณ ู†ูุชุฑุถ ุฅู†ุณุงู† AB ุดูˆ ุตุงุฑ ููŠู‡

547
00:53:54,000 --> 00:53:59,340
ู‡ุฐุง ุงู„ุฅู†ุณุงู†ุŸ ู„ุงุฒู… ูŠูƒูˆู† ุฃุฎุฐ ุงู„ู€A ู…ู† ุงู„ุฃุจ ูˆุฃุฎุฐ ุงู„ู€B

548
00:53:59,340 --> 00:54:04,840
ู…ู† ุงู„ุฃู… ู…ุซู„ุง ุฃูˆ ุงู„ุนูƒุณูุงู„ููƒุฑุฉ ุฅู†ู‡ ููŠ ุนู†ุฏูŠ Two

549
00:54:04,840 --> 00:54:09,040
Chromosomes ู„ู‡ุฐุง ุงู„ู‚ู„ูŠู„ ุงู„ุขู† ุงู„ู„ูŠ ู‡ูŠุญูƒูŠ ุฃู†ุง ุจู‡ู…ู†ูŠ

550
00:54:09,040 --> 00:54:16,020
ููŠ ุนู†ุฏูŠ ู†ุณุฎุชูŠู† ู…ูˆุฌูˆุฏุฉ ู…ู† ุงู„ุฃุจ ูˆุงู„ุฃู… ูˆูƒู„ ูˆุงุญุฏ ู…ูˆุฌูˆุฏ

551
00:54:16,020 --> 00:54:22,920
ุนู„ู‰ Chromosome ุชุจุนู‡ ูˆูƒู„ ูˆุงุญุฏ ุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ุฌูŠู† ู…ูˆุฌูˆุฏ

552
00:54:22,920 --> 00:54:31,390
ุฃุซู†ุงุก ุญุงู„ุฉ ุงู„ู€ ABO System ู†ูุชุฑุถ ู„ุญุงู„ุฉ ุฅู†ุณุงู† ABุงู„ู„ูŠ

553
00:54:31,390 --> 00:54:35,790
ุฑุงุญ ูŠุตูŠุฑ ุนู†ุฏู‰ ุจูŠุณู…ูŠู‡ ููˆู‚ Balanced Expression ุดูˆ

554
00:54:35,790 --> 00:54:41,370
ูŠุนู†ูŠุŸ ูŠุนู†ูŠ ู„ู…ุง ุฃู†ุง ุฃุฌู‰ ุฃุญูุธู‡ ุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ุจุฑูˆุชูŠู†

555
00:54:41,370 --> 00:54:44,890
ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€ enzyme ุงู„ู„ูŠ ุฑุงุญ ูŠุบูŠุฑ ุงู„ู€ H-antigen ู„ู„ู€

556
00:54:44,890 --> 00:54:49,530
A B-antigen ุจุญูŠุซ ุฅู†ู‡ ุฃู†ุง ุจู„ู…ุง ุฃู„ุงู‚ูŠ ุงู„ู€ A ูˆุงู„ู€ B

557
00:54:49,530 --> 00:54:54,290
-antigen ู…ุนู†ุงุชู‡ ุงู„ู€ enzyme ู…ูˆุฌูˆุฏ ูˆุงู„ู€ enzyme ุฃุฌู‰

558
00:54:54,290 --> 00:55:05,150
ู…ู† ุงู„ู€ RNA ุงู„ู„ูŠ ุฃุฌู‰ ู…ู† ุงู„ู€ DNAู„ู…ุง ุฃู†ุง ุขุฌูŠ ุฃุดูˆู ูƒู…

559
00:55:05,150 --> 00:55:09,910
ุนู†ุฏู‡ ู…ู† ู‡ุฐุง ุงู„ู†ูˆุน ูˆู…ู† ู‡ุฐุง ุงู„ู†ูˆุน ู…ู† ุงู„ู€ DNA ูˆู…ู† ุงู„ู€

560
00:55:09,910 --> 00:55:19,670
RNA ุฑุงุญ ุฃู„ุงู‚ูŠ ุฅู† ุงู„ู€ Two copies ู…ู† ุงู„ู…ุตุฏุฑูŠู†

561
00:55:19,670 --> 00:55:29,190
ุฃุซู†ูŠู†ู‡ู… ุดุบู„ุชุŒ ู…ุงุดูŠุŸ ุงู„ู…ุซุงู„ ุนู†ุฏูƒู… ู‡ู†ุงุญุทูŠู†ู‡ ุฅู†ู‡ ุฃู†ุง

562
00:55:29,190 --> 00:55:34,830
ุจุฏุฑุณ ุงู„ู…ูˆุถูˆุน ุชุจุน ุฅู†ู‡ ุงู„ู€ ยซRNAยป ู„ู„ูŠ ู…ู† ุฃุจูˆูŠ ููŠ SNP

563
00:55:34,830 --> 00:55:39,230
ุฅู†ู‡ ููŠ ู‡ุฐุง ุงู„ู…ูƒุงู† Single Nucleotide Polymorphism

564
00:55:39,230 --> 00:55:45,350
ูŠุนู†ูŠ ู„ู…ุง ู‚ุฑูŠุชู‡ ูƒู„ ุงู„ู…ุชุดุงุจู‡ุงุช ู…ุนุงุฏุฉ ุจุณ ููŠ ู…ูƒุงู† ูˆุงุญุฏ

565
00:55:45,350 --> 00:55:53,430
ู‡ุฐุง ุทู„ุน ยซGยป ู…ุด ุงู„ู€ ยซAยป ู…ุงุดูŠุŒ ูู‡ุฐู‡ ุจู†ุณู…ูŠู‡ุง ยซSNPยปุงู„ู€

566
00:55:53,430 --> 00:55:58,990
SNP ู‡ุฐุง ุฎู„ู‘ุชู†ูŠ ุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ู€ RNA ุฃู‚ุฏุฑ ุฃูุฑู‘ู‚ ุจูŠู†ู‡ู…

567
00:55:58,990 --> 00:56:05,810
ุฃู…ุง ูˆุธูŠููŠุงู‹ ูƒุดูŠุก ููŠ ุงู„ูˆุธูŠูุฉ ูŠู…ูƒู† ุฃุซู†ูŠู†ู‡ู… ุจูŠุคุฏูŠ

568
00:56:05,810 --> 00:56:09,490
ู„ู†ูุณ ุงู„ู€ Amino Acid ูˆุจุงู„ุชุงู„ูŠ ู…ุง ููŠ ุงุฎุชู„ุงู ุจุงู„ูˆุธูŠูุฉ

569
00:56:09,490 --> 00:56:14,150
ูŠุนู†ูŠ ู‡ูˆ ู…ุด ุฅู†ู‡ ุงุฎุชู„ููˆุง ุนู† ุจุนุถ ุจุณ ู‡ูŠ ู‚ุงู„ูŠุฉ ู‚ุฑุงุกุฉ

570
00:56:14,150 --> 00:56:22,070
ูˆูู‡ู… ู…ู† ูˆูŠู† ุฃุฌุช ู‡ุฐู‡ ุงู„ู€ RNAูู‡ู†ุง ุจุงู„ู…ุซุงู„ ุงู„ู„ูŠ

571
00:56:22,070 --> 00:56:26,950
ุญุงุทูŠู†ู‡ ุงู„ู€Snap ุฅู†ู‡ ุนู„ู‰ ุงู„ู…ุตุฏุฑ ู‡ุฐุง ุงู„ู„ูŠ ู‡ูˆ ุถู…ู†

572
00:56:26,950 --> 00:56:34,450
ุงู„ู€App ุจูŠูƒูˆู† ุฅู†ู‡ ููŠู‡ ุงู„ู€T ู‡ู†ุง ูˆู‡ู†ุง ู…ู† ุงู„ู€M ููŠู‡

573
00:56:34,450 --> 00:56:41,030
ุงู„ู€C ูุงู„ู€RNA ุฑุงุญ ูŠูƒูˆู† ู‡ู†ุง ุงู„ู€G ูˆู‡ู†ุง ุงู„ู€A ูู„ู…ุง ูŠูƒูˆู†

574
00:56:41,030 --> 00:56:45,550
ุนู†ุฏูŠ ุญุงู„ุฉ ุฒูŠ ู…ุซู„ุง ูˆุงุญุฏ blood group ุชุจุนุชู‡ AB blood

575
00:56:45,550 --> 00:56:51,490
groupููŠู‡ Expression Balanced ุฑุงุญ ูŠูƒูˆู† ู…ุนุฑูˆู ุงู„ู€ A

576
00:56:51,490 --> 00:57:00,270
ูˆุงู„ู€ B ูˆู†ุฎุชุงุฑ ุฃู†ู‡ู… ุฒูŠ ุจุนุถุŒ ู…ุงุดูŠ ูู‡ูŠ ุธุงู‡ุฑุฉ ุจุชุญุฏุซ ุฃู†

577
00:57:00,270 --> 00:57:07,950
ุฃุญูŠุงู†ู‹ุง ููŠ ุฌูŠู†ุงุช ู„ู…ุง ู†ูƒูˆู† ุนู†ุฏู‡ Two copies ุฃุซู†ุงู† ู‡ู…

578
00:57:07,950 --> 00:57:13,670
ุดุบุงู„ูŠู† ุจู…ุง ูŠุฑุถูŠ ุงู„ู„ู‡ ุจุญูŠุซ ุฃู†ู‡ ุงู„ุจุฑูˆุชูŠู† ุงู„ู†ุงุชุฌ ู…ู†

579
00:57:13,670 --> 00:57:20,450
RNAู„ู‚ู†ุง ุจู†ุณุจุฉ 50% ู„ู‡ุฐุง ุงู„ู†ูˆุน ูˆ50% ู…ู† ู‡ุฐุง ุงู„ู†ูˆุนุŒ

580
00:57:20,450 --> 00:57:27,770
ู…ุงุดูŠุŸ ุงู„ุขู† ู†ุงุฎุฏ ุงู„ู…ุซุงู„ ุงู„ู„ูŠ ุชุญุช ูˆุจุฏู‰ ุฃู†ุง ุฃุฑูƒุฒ ุนู„ูŠู‡

581
00:57:27,770 --> 00:57:33,170
ู…ู† ู†ุงุญูŠุฉ ุงู„ู„ูŠ ุฃู†ู‡ ููŠ ุงู„ู…ู†ุงุนู… ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€ Light

582
00:57:33,170 --> 00:57:39,490
Chain ูˆุงู„ู€ Heavy Chain ุชุจุน ุงู„ู€ Immunoglobulin ุงู„ู€

583
00:57:39,490 --> 00:57:44,310
Immunoglobulin ู…ุซู„ุง ุงู„ู€ Light Chain ู†ุนุฑู ููŠู‡ Kappa

584
00:57:44,310 --> 00:57:52,820
ูˆLambdaูˆุงู„ู€ Lambda ูˆุงู„ู€ Kappa ู…ู†ูŠ ุนู†ุฏูŠ ู†ูˆุนูŠู† ูˆุงุญุฏ

585
00:57:52,820 --> 00:57:57,340
ู…ู† ุฃุจูˆูŠ ูˆูˆุงุญุฏ ู…ู† ุฃู…ูŠ ูˆุงู„ู€ Lambda ุนู†ุฏูŠ ุจุฑุถู‡ ู†ูˆุนูŠู†

586
00:57:57,340 --> 00:58:04,360
ูˆุงุญุฏ ู…ู† ุฃุจูˆูŠ ูˆูˆุงุญุฏ ู…ู† ุฃู…ูŠ ูุจุงู„ู†ุณุจุฉ ู„ู„ู€ Light Chain

587
00:58:04,360 --> 00:58:12,600
Gene ููŠ ุนู†ุฏูŠ ุฃุฑุจุน copies ู‡ุฐูˆู„ุฉ ุฃุฑุจุน copies ู…ูˆุฌูˆุฏุฉ

588
00:58:12,600 --> 00:58:18,350
ููŠ ูƒู„ ุฎู„ุงูŠุง ุงู„ุฌุณู…ูˆููŠ ุงู„ุฌูŠู†ุงุชุŒ ููŠ ุงู„ู€DNAุŒ ุนู„ู‰

589
00:58:18,350 --> 00:58:24,830
ุงู„ู€Chromosome ุฃุธู† Chromosome 22ุŒ ูˆู‡ู†ุงูƒู… ู…ูˆุฌูˆุฏูŠู†ุŒ

590
00:58:24,830 --> 00:58:32,430
ู…ุงุดูŠุŒ ุงู„ุดูŠุก ุงุณู…ู‡ุŒ ุงู„ุฃุฑุจุนุฉ ู…ูˆุฌูˆุฏูŠู†ุŒ Chromosomes

591
00:58:32,430 --> 00:58:39,910
222ุŒ ูุนู†ุฏูŠ ุฃุฑุจุนุฉ ู†ุตููŠู†ุŒ ููŠ ุฃูŠ ุฎู„ูŠุฉ ููŠ ุงู„ุฌุณู…ุŒ ูŠุนู†ูŠ

592
00:58:39,910 --> 00:58:42,770
ุฃู†ุง ุจู…ุณูƒ ุงู„ู€B-Lymphocytes ุงู„ู…ุณุคูˆู„ุงุช ุนู†

593
00:58:42,770 --> 00:58:47,530
ุงู„ู€ImmunoglobulinsูˆุจุงุฌูŠ ุจุฏุฑุณู‡ู… ููŠ ุงุฎุชู„ุงูุงุช ุจูŠู†ู‡ู…

594
00:58:47,530 --> 00:58:53,530
ุฅู†ู‡ ูƒู„ ูˆุงุญุฏ ู…ู†ู‡ู… ู…ู† ุงู„ุฃุฑุจุน ู†ุณุฎ ู…ู† ุงู„ุฌูŠู†ุงุช ูˆุงุญุฏุฉ

595
00:58:53,530 --> 00:58:58,850
ุจุชูƒูˆู† ุดุบุงู„ุฉ ูŠุนู†ูŠ ุฃู†ุง ุจุงุฌูŠ ู‡ู†ุง ุฃุฏุฑุณ ุงู„ู€ Protein

596
00:58:58,850 --> 00:59:04,050
ุงู„ู†ุงุชุฌ ูˆู„ู‡ ุฌุงูŠ ู…ู† ุงู„ู€ RNA ูุฃู†ุง ุฏุฑุณุช ุงู„ู€ RNA ุงู„ู†ุงุชุฌ

597
00:59:04,050 --> 00:59:10,490
ุจู„ุงู‚ูŠ ู‡ุฐุง ูƒู„ู‡ ุฅูŠู‡ ูุงู„ู„ูŠ ุตุงุฑ ุฅู†ู‡ ููŠ ู‡ุฐู‡ ุงู„ุฎู„ูŠุฉ

598
00:59:10,490 --> 00:59:13,310
ุชุญุฏูŠุฏุงู‹

599
00:59:14,280 --> 00:59:17,840
ู‡ุฐู‡ ุงู„ู†ุณู‚ุฉ ู‡ูŠ ุงู„ู„ูŠ ุดุบุงู„ุฉ ูˆู‡ุฐู‡ ุงู„ู†ุณู‚ุฉ ุชู…ุงู…ู‹ุง ู…ุด

600
00:59:17,840 --> 00:59:25,560
ุดุบุงู„ุฉ ูˆุงุถุญุŸ ูู‡ุฐู‡ ุฃุญูŠุงู†ู‹ุง ุธุงู‡ุฑุฉ ุจุชุญุฏุซ ุจู†ุณู…ูŠู‡ุง ุงู„ู€

601
00:59:25,560 --> 00:59:30,240
Monoallelic Expression ุฃูˆ ุจุงู„ู€ ุฏุงุฆู…ู‹ุง ุจูŠู‚ูˆู„ูˆู†ู‡ุง

602
00:59:30,240 --> 00:59:35,220
Allelic Exclusion ูŠุนู†ูŠ ุฅู†ู‡ ุฅุฐุง ุงุดุชุบู„ ูˆุงุญุฏ ุจูŠู…ู†ุน

603
00:59:35,220 --> 00:59:39,260
ุงู„ุซุงู†ูŠ ูŠุดุชุบู„ ูู‡ุฏูˆู„ุฉ

604
00:59:39,260 --> 00:59:45,400
ุฒูŠ ู…ุง ุชู‚ูˆู„ Two Extremes ูŠุง ุฅู…ุง50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ

605
00:59:45,400 --> 00:59:45,760
50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ

606
00:59:45,760 --> 00:59:55,880
50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ

607
00:59:55,880 --> 01:00:00,760
50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ

608
01:00:00,760 --> 01:00:01,600
50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ

609
01:00:01,600 --> 01:00:03,980
50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ

610
01:00:03,980 --> 01:00:08,320
50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ

611
01:00:08,320 --> 01:00:09,560
50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ 50%ุŒ

612
01:00:09,560 --> 01:00:20,660
50%ุŒ 50%ูู‡ู†ุง ุฃู†ุง ุงุณุชุฎุฏู…ุช ุขู„ูŠุฉ ุงู„ู€ Snip ูˆู„ู‚ูŠุช ุจู…ุญุถ

613
01:00:20,660 --> 01:00:25,980
ุงู„ุตุฏูุฉ ุญุธ ุงู„ูˆุงุญุฏ ูŠูƒูˆูŠุณ ุฅู†ู‡ ููŠู‡ Snip ู…ุนูŠู† ูˆุงุถุญ

614
01:00:25,980 --> 01:00:31,200
ุจูŠูุฑู‚ู„ูŠ ุฅู† ู‡ุฐุง ุฌุงูŠ ู…ู† ูˆูŠู† ูˆู‡ุฐุง ุฌุงูŠ ู…ู† ูˆูŠู† ุฅุฐุง ู„ู‚ูŠุช

615
01:00:31,200 --> 01:00:38,100
ุฅุดูŠ ูˆุจู‚ุฏุฑ ุฃู‚ูŠู… ู‚ุฏุงุด ุดุบู„ ูƒู„ ู‚ู„ูŠู„ ู…ู† ุงู„ู€Gene ู‡ุฐุง

616
01:00:38,100 --> 01:00:39,700
ูˆุงุถุญุฉ

617
01:00:43,240 --> 01:00:47,380
ููŠ ุฃุณุฆู„ุฉุŸ ููŠ ุณุคุงู„ุŒ ูŠุง ุฏูƒุชูˆุฑุŒ ุนู„ู‰ ุงู„ู€ ยซุณู„ุงูŠุฏยป

618
01:00:47,380 --> 01:00:51,160
ุงู„ุณุงุจู‚ ุงู„ู…ูˆุถูˆุน ุงู„ู€ Subchromosomal domains ุงู„ู„ูŠ

619
01:00:51,160 --> 01:00:56,100
ู…ูˆุฌูˆุฏ ููŠ ุงู„ู„ูŠ ู‡ูˆ ุงู„ุตูˆุฑุฉ ยซAยป ุจุชุณุฃู„ุŒ ุจุชุณุฃู„ ุงู„ุฏูƒุชูˆุฑุฉ

620
01:00:56,100 --> 01:00:57,860
ุฃูŠุด ุงู„ูุฑู‚ ุจูŠู† ุงู„ู€ ยซChromosomeยป ูˆุงู„ู€

621
01:00:57,860 --> 01:01:00,080
ยซSubchromosomal domainsยป ุฃูˆ ุงู„ู€ ยซChromosomal

622
01:01:00,080 --> 01:01:02,580
domainsยป ุฃู‡ ุงู„ู€ ยซSubchromosomal domainsยป ูˆุงู„ู€

623
01:01:02,580 --> 01:01:07,280
ยซChromosomeยป ุฃูŠุด ุงู„ูุฑู‚ ุจูŠู†ู‡ู…ุŸ ู„ุฃุŒ ู„ุฃุŒ ุงู„ุญูŠู† ุงู„ู€

624
01:01:07,280 --> 01:01:12,160
ยซChromosomesยป ุฃู†ุช ุจุชุดูˆูู‡ุง ููŠ ุญุงู„ุฉ ุงู„ู€ ยซKaryotypeยป

625
01:01:13,720 --> 01:01:19,700
ุงู„ู„ูŠ ู‡ูˆ ุงู„ุดูƒู„ ุงู„ู…ุถุบูˆุท ุชู…ุงู…ู‹ุง ุงู„ู„ูŠ ุจู†ุณุชููŠุฏ ุฃูˆ

626
01:01:19,700 --> 01:01:26,580
ุจุญุงุฌุชู‡ ู„ู…ุง ุงู„ุฎู„ูŠุฉ ุชู†ู‚ุณู…ุŒ ู‡ูŠ ุนู†ุฏ ุงู„ุงู†ู‚ุณุงู…ุŒ ู…ุงุดูŠุŸ

627
01:01:26,580 --> 01:01:30,860
ุญุชู‰ ุงู„ู€ ยซDNAยป ูŠุดุชุบู„ ูˆุงู„ู€ ยซChromosomeยป ูˆุงู„ู€

628
01:01:30,860 --> 01:01:37,800
ยซWerabiยป ุชุดุชุบู„ุŒ ุจุณ ู„ุงุฒู… ุงู„ู€ ยซDNAยป ู…ุง ูŠูƒูˆู† ุจู‡ุฐุง

629
01:01:37,800 --> 01:01:43,960
ุงู„ุดูƒู„ ุงู„ู…ุถุบูˆุทุŒ ู„ุงุฒู… ูŠููƒุŒ ูุงู‡ู… ุนู„ูŠูƒุŸูู„ู…ุง ุชู‚ูˆู„ ุฅู†ู‡

630
01:01:43,960 --> 01:01:50,940
Fact ุงู„ู„ูŠ ุฑุงุญ ูŠุตูŠุฑ ุฅู†ู‡ ููŠ ุงู„ู€ Nucleus ูƒู„ ูƒุฑูˆู…ูˆุฒูˆู…

631
01:01:50,940 --> 01:01:58,380
ูƒุฃู†ู‡ ู…ุงุฎุฐ ุญูŠุฒ ู…ุงุดูŠ ุฃุญูŠุงู†ู‹ุง ููŠ ู…ุณุงุนุฏุฉ ุจูŠู† ุจุนุถ

632
01:01:58,380 --> 01:02:04,220
ุงู„ู…ุณุงุนุฏุฉ ุงู„ู…ุทู„ูˆุจุฉ ุฅู† ุฃุญูŠุงู†ู‹ุง ุงู„ู€ Promoter Region

633
01:02:04,220 --> 01:02:11,100
ู‡ูˆ ู‚ุทุนุฉ ุจุดูƒู„ ุนู„ู‰ ุงู„ู€ Primary Structure ุฃูˆ ุนู„ู‰ุงู„ู€

634
01:02:11,100 --> 01:02:17,020
ยซู„ูˆยป ุนู„ู‰ ุงู„ุญุจู„ ุฃูˆ ุงู„ุฎูŠุฑ ุชุจุน ุงู„ู€ ยซDNAยป ู‡ูŠ ู…ู†ุทู‚ุฉ

635
01:02:17,020 --> 01:02:26,680
ุจุนูŠุฏุฉ ูู„ุงุฒู… ูŠุตูŠุฑ ุงู„ .. ูˆูŠู† ุฃู†ุช ุจุชุญูƒูŠ ุงู„ู€ domainุŸ

636
01:02:26,680 --> 01:02:31,260
ุดูˆู ุชุญุชุŒ ุดูˆ ุงู„ู„ูŠ ุจุชุญูƒูŠ ุฃู†ุช ุนู†ู‡ุงุŸ ููŠ ููŠ ุงู„ุตูˆุฑุฉ ุฃูˆ

637
01:02:31,260 --> 01:02:36,160
ููŠ ุงู„ุชุนู„ูŠู‚ ุนู„ู‰ ุงู„ุตูˆุฑุฉ BASF ุจูŠู‚ูˆู„ ุฅู† ุงู„ู€ ยซChromatin

638
01:02:36,160 --> 01:02:40,240
Organized Enlarged Subchromosomaldomain within

639
01:02:40,240 --> 01:02:44,840
each territory with loops ุฏู‡ ุทุจุนุงู‹ ุจูŠูƒู…ู„ุŒ ุจูŠูุตู„

640
01:02:44,840 --> 01:02:48,440
ุฅูŠุด ุงู„ interaction ุจุณุŒ ูุจุชุณุฃู„ ุฅูŠุด ุงู„ูุฑู‚ ู…ุง ุจูŠู†

641
01:02:48,440 --> 01:02:51,720
ุงู„ู€subchromosome ุงู„ุฏู…ูŠู† ุงู„ู„ูŠ ุจูŠุญูƒูŠ ุนู†ู‡ุง ุฃู†ุง ูˆ

642
01:02:51,720 --> 01:02:56,880
ุงู„ู€chromosomeุŒ ูŠุนู†ูŠ ุญุชุฉ โ€ฆ ู„ุฃุŒ ู„ุฃุŒ ุฅุณู…ุนู„ูŠุŒ ุฅุณู…ุนู„ูŠุŒ

643
01:02:56,880 --> 01:03:04,200
ุงู„ู€chromosome ู‡ูˆ ุงู„ุฎูŠุฑ ู„ูุฉ ุญุจู„ุŒ ู…ุงุดูŠุŸ ุฃู†ุช ู„ู…ุง ุชุฑูˆุญ

644
01:03:04,200 --> 01:03:09,310
ุชุดุชุฑูŠู‡ุง ู…ุซู„ุง ู…ู† ุนู†ุฏ ุงู„ุจู‚ุงู„ุฉุŒ ูƒูŠู ุชุดุชุฑูŠ ุงู„ุญุจู„ุŸุจุฏูˆ

645
01:03:09,310 --> 01:03:15,990
ูŠุนุทูŠูƒ ุฅูŠุงู‡ ู…ู„ููˆู ูˆู…ุฑุจูˆุท ูˆูƒุฐุงุŒ ุตุญุŸ ุตุญุŸ ุชู…ุงู… ู„ู…ุง

646
01:03:15,990 --> 01:03:23,450
ุชูŠุฌูŠ ุจุฏูƒ ุชุณุชุฎุฏู…ู‡ ูุนู„ูŠู‹ุงุŒ ู…ุงุดูŠุŸ ุจุฏูƒ ุชููƒู‡ุŒ ุตุญุŸ ุตุญูŠุญ

647
01:03:23,450 --> 01:03:29,710
ุงู„ููƒ ูˆุงู„ุฑุจุท ู…ู† ุฎู„ุงู„ ุงู„ุชุฑุชูŠุจ ู‡ุฐุง ุจุณ ููŠ ุฏุงุฎู„ ุงู„ู†ูˆุงุก

648
01:03:29,710 --> 01:03:35,590
ูƒู„ ูƒุฑูˆู…ูˆุฒูˆู… ุฒูŠ ูƒุฃู†ู‡ ู…ุงุฎุฐ ุฌู‡ุฉ ุญุชู‰ ู‡ูŠูƒ ูŠุงุฎุฏ ุฑุงุญุชู‡

649
01:03:35,590 --> 01:03:41,150
ุฅู†ู‡ ูŠููƒู‡ุŒ ู…ุงุดูŠุŸ ุตุญูŠุญุจู‡ุฐู‡ ุงู„ู†ุงุญูŠุฉุŒ ุญุณู†ุงู‹ุŒ ููŠ ู…ู„ุงุญุธุฉ

650
01:03:41,150 --> 01:03:47,010
ุซุงู†ูŠุฉ ุญุชู‰ ุฃูŠ ู‚ุทุน ุงู„ุฌูŠู† ุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ุฌูŠู† ุญุณู†ุงู‹ุŒ

651
01:03:47,010 --> 01:03:52,070
ุงู„ู€Chromosome ุงู„ูˆุงุญุฏ ููŠู‡ ุฃู„ู ุฌูŠู†ุŒ ุตุญุŸ ุตุญูŠุญ ุงู„ุฌูŠู†

652
01:03:52,070 --> 01:03:57,130
ุงู„ูˆุงุญุฏุŒ ุญุชู‰ ูŠุดุชุบู„ุŒ ู„ุงุฒู… ูŠูƒูˆู† ููŠู‡ ุชู‡ูŠุฆุฉ ู…ู† ู…ู†ุทู‚ุฉ

653
01:03:57,130 --> 01:04:03,150
ู‚ุจู„ู‡ ุฅู†ู‡ ููŠู‡ Promoter RegionุŒ ููŠ ู…ู†ุทู‚ุฉ ุจุฏู‡ุง ูŠุนู†ูŠ

654
01:04:03,150 --> 01:04:08,210
ุชู‡ูŠุฆ ุฃู†ู‡ ุขู‡ ูˆุงู„ู„ู‡ุŒ ุงุจุฏุฃ ุฃู‚ุฑุฃ ู…ู† ู‡ู†ุงุงู„ู„ูŠ ู‡ูŠ ุงู„ู€

655
01:04:08,210 --> 01:04:14,550
Starton Codon ู„ู„ุจุฏุงูŠุฉ ูุงู„ู€ Promoter Regions

656
01:04:14,550 --> 01:04:20,950
ุฃุญูŠุงู†ู‹ุง ู‚ุฏ ุชูƒูˆู† ุฅูŠุด ุงู„ู„ูŠ ู‡ูŠ ุงู„ุฌุฒุก ุงู„ู…ุจุงุดุฑ ูˆุฃุญูŠุงู†ู‹ุง

657
01:04:20,950 --> 01:04:26,150
ุจุชูƒูˆู† ู…ู†ุทู‚ุฉ ุจุนูŠุฏุฉ ูˆุฃุญูŠุงู†ู‹ุง ุฒูŠ ู…ุง ุญุงุทูŠู† ู‡ู†ุง ู…ู† ู„ุณู‡

658
01:04:26,150 --> 01:04:32,750
ูุชุนุฉ ุซุงู†ูŠุฉ ูŠุนู†ูŠ ูŠุนู†ูŠ ุฒูŠ ู…ุง ู‡ู… ุญุงุทูŠู† ู‡ู†ุง ุฃู†ู‡ ยซhighยป

659
01:04:32,750 --> 01:04:39,610
ูˆ ยซhighยป ูŠุนู†ูŠ ููŠู‡ ูƒุฑูˆู…ูˆุฒูˆู…ุงู„ุฌูŠู† ูˆูŠูƒูˆู† ุงู„ู€ Promoter

660
01:04:39,610 --> 01:04:46,390
Region ุชุจุนู‡ ุจุงุชุญุงุฌ ู„ู‚ุทุน ุซุงู†ูŠ ู…ู† ุฎูŠุท ุซุงู†ูŠ ู…ูˆุฌูˆุฏ

661
01:04:46,390 --> 01:04:50,250
ุฌู†ุจู‡ุŒ ุจุณ ู„ุงุฒู… ูŠูƒูˆู† ุฌู†ุจู‡ ุจุญูŠุซ ุฃู†ู‡ ูŠู‚ุฏุฑ ูŠุชูุงุนู„ ู…ุนุงู‡ุŒ

662
01:04:50,250 --> 01:04:53,050
ุญุชู‰ ู„ูˆ ู‡ูˆ ุจุนูŠุฏ ุนู† ุจุนุถุŒ ูˆุงุถุญุฉุŸ

663
01:04:56,080 --> 01:05:00,280
ุชู…ุงู…ุŒ ูŠุนู†ูŠ ุฏูƒุชูˆุฑุฉ ุฃุชู…ู†ู‰ ูŠูƒูˆู† ุณุคุงู„ ูˆุถุญ ูŠุนู†ูŠ ุฏูƒุชูˆุฑุฉ

664
01:05:00,280 --> 01:05:04,200
ุฃุณู…ุงุกุŒ ู‡ูˆ ูŠุนู†ูŠ ุงู„ู„ูŠ ุงู„ู…ู‚ุตูˆุฏ ุบุงู„ุจู‹ุง ุงู„ุญูŠุซ ุงู„ู„ูŠ

665
01:05:04,200 --> 01:05:07,940
ุจูŠุญุชู„ูˆุง ุงู„ูƒุฑู…ูˆุฒูˆู… ู…ู† ุงู„ู†ูˆุงุก ุจุดูƒู„ ุฑุฆูŠุณูŠุŒ ู‡ูˆ ุงู„ุณุจู‚

666
01:05:07,940 --> 01:05:10,940
ูƒุฑู…ูˆุฒูˆู… ุงู„ุฏูˆู„ูŠ ุฃูุถู„ุŒ ู„ู…ุง ู†ูƒูˆู† ููŠ ุงู„ู†ูˆุงุกุŒ ู„ุงุฒู… ูŠูƒูˆู†

667
01:05:10,940 --> 01:05:16,800
ู…ููƒูˆูƒ ุฒูŠุงุฏุฉ ุตุญูŠุญ ู…ู…ูƒู† ุชุดุชุบู„ ุนู„ูŠู‡ ูˆุงู†ุช ู„ูู‡ ู„ู ุดุฏูŠุฏุŒ

668
01:05:16,800 --> 01:05:22,490
ู…ู…ูƒู†ุด ุชู‚ุฑุง ู…ู†ู‡ ุฅูŠุดุŒ ู„ุงุฒู… ุชููƒู‡ ู‡ูŠูƒ ุดูˆูŠุฉูˆู„ู…ู‘ุง ุจุฏูƒ

669
01:05:22,490 --> 01:05:26,690
ุชุตู„ ู„ู„ู…ู†ุทู‚ุฉ ุงู„ู„ูŠ ุจุฏูƒ ุฅูŠุงู‡ุง ุถุฑูˆุฑูŠ ูƒุชูŠุฑ ูƒุชูŠุฑ ู„ุณู‡ ุจุฏูƒ

670
01:05:26,690 --> 01:05:34,750
ุชููƒู‡ุง ุฃูƒุซุฑุŒ ูˆุงุถุญุŸ ุฅู† ุดุงุก ุงู„ู„ู‡ ูุงู„ุขู† ูŠุนู†ูŠ ุฅุญู†ุง ุงู„ู„ูŠ

671
01:05:34,750 --> 01:05:41,150
ุจุฏู†ุง ู†ุญูƒูŠ ุฅู†ู‡ ู…ู† ุงู„ุธูˆุงู‡ุฑ ุงู„ู„ูŠ ูƒู…ุงู† ุงู„ู…ูˆุฌูˆุฏุฉ ุฅู†ู‡

672
01:05:41,150 --> 01:05:53,840
ุฃุญูŠุงู†ู‹ุง ุงู„ู€โ€ฆ ุงู„ู€โ€ฆ ุงู„ู€Expression ุชุจุนุงู„ู€ DNA ูŠุนู†ูŠ

673
01:05:53,840 --> 01:05:57,460
ุงู„ู€ expression ู„ู„ู€ DNA ู„ู„ุฌูŠู† ูŠุนู†ูŠ ู‚ุถูŠุฉ ุดูˆ ุงู„ู„ูŠ

674
01:05:57,460 --> 01:06:02,800
ูŠู‚ุฑุฃุŒ ู…ุงุดูŠุŸ ูˆู„ูŠุด ุฃูŠ ุฎู„ูŠุฉ ููŠู‡ุง ุงู„ุฌูŠู† ุงู„ู„ูŠ ูู„ุงู†ูŠ

675
01:06:02,800 --> 01:06:09,260
ูŠู‚ุฑุฃ ุณูˆุงุก ู†ุชูŠุฌุฉ ูŠุนู†ูŠ ู…ู† ุงู„ู€ chromosome ุงู„ู„ูŠ ู…ู†

676
01:06:09,260 --> 01:06:12,720
ุงู„ุฃุจ ูˆู„ุง ู…ู† ุงู„ุฃู…ุŒ ูŠุนู†ูŠ ู‡ุฐู‡ ุงู„ู„ูŠ ู‡ูŠ ุงู„ู€ Allelic

677
01:06:12,720 --> 01:06:17,600
imbalanceุŒ ูŠุนู†ูŠ ุฃู‡ู…ูŠุฉ ุฃู†ู‡ุฃุญูŠุงู†ู‹ุง ูŠุนู†ูŠ ู†ูุชุฑุถ ุฃู†ุง

678
01:06:17,600 --> 01:06:25,340
ุนู†ุฏูŠ Two copies ุฃุจูˆูŠ ู…ุฑูŠุถ ุนู†ุฏู‡ ู…ุฑุถ ู…ุนูŠู† ู…ุซู„ู‹ุง

679
01:06:25,340 --> 01:06:30,220
Female patient ูˆุงู„ุฏู‡ุง ุฃุฎุฐุช Two X-Chromosomes ูˆุงุญุฏ

680
01:06:30,220 --> 01:06:34,180
ู…ู† ุงู„ุฃู… ูˆูˆุงุญุฏ ู…ู† ุงู„ุฃุจ ุงูุฑุถ ุงู„ุฃุจ ุนู†ุฏู‡ ู…ุฑุถ

681
01:06:34,180 --> 01:06:41,120
Hemophilia ู‡ู„ ุงู„ู€Hemophilia ู‡ูŠ ุนู†ุฏู‡ุง ูˆุงุญุฏ ุดุบุงู„ ู…ู†

682
01:06:41,120 --> 01:06:46,530
ุงู„ุฃู…ุŒ ุตุญุŸุจุณ ู‡ู„ ุฏุงูŠู…ุงู‹ ูู‚ุท ุงู„ุฃู… ุงู„ู„ูŠ ูŠุดุบุงู„ูŠ ูˆู…ุงููŠุด

683
01:06:46,530 --> 01:06:50,890
ุฅุดูŠ ู…ู† ุงู„ุฃุจ ูˆู„ุง ุดูˆ ุฏุฎู„ู‡ ูˆู„ุง ูƒุฏู‡ ูู„ู…ุง ูŠูƒูˆู† ุนู†ุฏูŠ

684
01:06:50,890 --> 01:06:56,510
ุธูˆุงู‡ุฑ ูŠุนู†ูŠ ุฃู†ุง ู‡ู†ุง ุจุญูƒูŠ ุงู„ู„ูŠ ู‡ูŠ ุงู„ู€ Unbalanced

685
01:06:56,510 --> 01:07:01,790
Expression ูŠุนู†ูŠ ุงู„ู„ูŠ ู‡ูŠ ุฅุญู†ุง ู†ูุชุฑุถ ุฒูŠ ุงู„ู€ ABO

686
01:07:01,790 --> 01:07:05,010
System ุฅู† ุฃุซู†ูŠู† ุฑุงุญ ูŠุดุชุบู„ูˆุง ูˆ ุฃุซู†ูŠู† ุฑุงุญ ูŠุฌูŠุจูˆุง

687
01:07:05,010 --> 01:07:08,650
ุฎู…ุณูŠู† ุจุงู„ู…ูŠุฉ ู…ู† ุงู„ู„ุงุฒู… ูˆูŠุนุทูˆู†ุง ุงู„ุฃุดูŠ ุงู„ูƒู…ูŠุฉ ุงู„ู„ูŠ

688
01:07:08,650 --> 01:07:13,300
ุฃู†ุง ุจุฏูŠู‡ุง ุฒูŠ ุงู„ู€ ABO Systemูู‡ุฐู‡ ุงู„ู„ูŠ ุจูŠูƒูˆู† ููŠู‡ุง

689
01:07:13,300 --> 01:07:18,500
ุงู„ู€ Allelic Balance ู†ุณู…ูŠู‡ ุจูŠูƒูˆู† ุงุซู†ูŠู†ู‡ุง ู…ุดุบู„ุฉ ุงู„ู€

690
01:07:18,500 --> 01:07:23,700
Unbalanced Expression ู‡ูˆ ู†ุญุทูŠู† ุฅู†ู‡ ุญูˆุงู„ูŠ ู…ู† ุฎู…ุณ

691
01:07:23,700 --> 01:07:27,080
ุฅู„ู‰ ุนุดุฑูŠู† ุจุงู„ู…ุฆุฉ ู…ู† ุงู„ู€ Autosomal Genes ูŠุนู†ูŠ ู‡ูŠ

692
01:07:27,080 --> 01:07:33,540
ุธุงู‡ุฑุฉ ุจุชุญุฏุซ ููŠ ู†ุณุจุฉ ู‚ู„ูŠู„ุฉ ู…ู† ุงู„ู€ Autosomal GenesุŒ

693
01:07:33,540 --> 01:07:38,680
ู†ุงุดูŠุŸ ูุงู„ู€ ู„ูŠุดุŸ

694
01:07:40,360 --> 01:07:47,580
ู‡ู†ุง ูŠุนู†ูŠ ุจุงู„ุฃุฎูŠุฑ Epigenetic Changes ูŠุนู†ูŠ ุธูˆุงู‡ุฑ

695
01:07:47,580 --> 01:07:51,580
ู…ุนูŠู†ุฉ ูŠู…ูƒู† ุฏุฑุฌุฉ ุงู„ู€ methylation ู„ู‡ุฐู‡ ุงู„ุฃุดูŠุงุก ุบูŠุฑ

696
01:07:51,580 --> 01:07:54,740
ุฏุฑุฌุฉ ุงู„ู€ methylation ู„ู‡ุฐุง ุงู„ู€ ูŠุนู†ูŠ ุงู„ู€ copy ู…ู†

697
01:07:54,740 --> 01:07:58,580
ุงู„ุฃุจ ุบูŠุฑ ุงู„ู€ copy ู…ู† ุงู„ุฃู… ููŠ ุฏุฑุฌุฉ ุงู„ู€ methylation

698
01:07:58,580 --> 01:08:05,160
ู…ุซู„ุงู‹ ูุฎู„ุช ูˆุงุญุฏุฉ ุชู‚ุฏุฑ ุชูƒูˆู† ุฃู†ุฌุญุฉ ู…ุซู„ุงู‹ ูˆู‡ุฐู‡ ูŠุนู†ูŠ

699
01:08:05,160 --> 01:08:11,470
ู†ุณุจุฉ ู‚ู„ูŠู„ุฉ ู…ู† ุงู„ุฌูŠู†ุงุช ุจุชุชุซุซุฑ ุจู‡ุฐู‡ ุงู„ุธุงู‡ุฑุฉูˆุงู„ู€ ูŠุนู†ูŠ

700
01:08:11,470 --> 01:08:21,650
ููŠ ุงู„ุบุงู„ุจ ู‡ุฐู‡ ููŠ ุงู„ู…ุฑุญู„ุฉ ุงู„ุฃูˆู„ู‰ ู…ู† ุงู„ุญูŠุงุฉ ุงู„ู†ูˆุงุญูŠ

701
01:08:21,650 --> 01:08:27,850
ุงู„ุซุงู†ูŠุฉ ุงู„ุฃู…ุซู„ ุงู„ุซุงู†ูŠุฉ ุญุงุทูŠู†ุง ุฃุฑุจุนุฉ ุฃู†ู‡ ุฃุฑุจุนุฉ

702
01:08:27,850 --> 01:08:32,250
ุจูŠูƒูˆู†ูˆุง ูˆุงุญุฏุฉ ู…ู† ุงู„ู€ Two copies ู‡ูŠ ุงู„ุดุบุงู„ุฉ

703
01:08:32,250 --> 01:08:38,530
ูˆุงู„ุซุงู†ูŠุฉ ู†ู‡ุงุฆูŠุง ู…ุด ุดุบุงู„ุฉุŒ ู…ุงุดูŠุŸูู‡ูŠ ุงู„ู„ูŠ ุจูŠุณู…ูˆู‡ุง

704
01:08:38,530 --> 01:08:42,210
ยซmonoallelic expressionยป ุญูƒูŠู†ุง ู‚ุจู„ ุดูˆูŠุฉ ุนู„ู‰

705
01:08:42,210 --> 01:08:45,550
ุงู„ุฎู„ุงูŠุง ุงู„ู…ู†ุนู… ุงู„ู€ ยซTยป ูˆุงู„ู€ ยซBยป ุงู„ู€ ยซLymphocytesยป

706
01:08:45,550 --> 01:08:48,590
ู„ู„ู€ ยซAmminoglobulinยป ุงู„ู€ ยซheavy and light chainsยป

707
01:08:48,590 --> 01:08:51,410
ูˆู„ู„ู€ ยซAlphaยป ูˆยซBetaยป ุงู„ู€ ยซChainsยป ุชุจุนุงุช ุงู„ู€ ยซT

708
01:08:51,410 --> 01:08:57,350
Cellยป ูู‡ุฏูˆู„ุฉ ููŠ ยซSomatic Rearrangementยป ูŠุนู†ูŠ

709
01:08:57,350 --> 01:09:06,220
ุจุทุฑูŠู‚ุฉ ู…ุง ุญุชู‰ ุชุตูŠุฑ ู…ูƒูˆู‘ู†ุฅู…ูƒุงู†ูŠุฉ ุฅู†ู‡ ูŠูƒูˆู† ุนู†ุฏู†ุง

710
01:09:06,220 --> 01:09:11,380
Antibodies ูˆู…ู†ุงุนุฉ ุชู‡ุงุฌู… ุฃูŠ ุฅุดูŠ ููŠ ุงู„ุญูŠุงุฉุŒ ุฃูŠ ุฅุดูŠ

711
01:09:11,380 --> 01:09:17,100
ููŠ ุงู„ูƒูˆู†ุŒ ุฃูŠ ุฅุดูŠ ู…ู…ูƒู† ู†ุชุนุฑุถ ุฅู„ูŠู‡ุŒ ูŠุนู†ูŠ ุงู„ู€TCR

712
01:09:17,100 --> 01:09:20,340
ูˆุงู„ู€Immunoglobulin ู†ุชูƒู„ู… ุนู† ุนุดุฑ ุฃูˆ ุฃุณ ุฃุญุฏุงุดุฑ ู„ุนุดุฑ

713
01:09:20,340 --> 01:09:25,260
ุฃูˆ ุฃุณ ุชู…ุงู†ุชุงุดุŒ AntibodiesุŒ Variable Region ูู„ู…ุง

714
01:09:25,260 --> 01:09:31,360
ุชูƒูˆู† ู‡ุฐู‡ ุงู„ุดุบู„ุฉ ุชู…ุชุŒ ุจุตูŠุฑ ู‚ุต ูˆู„ุณู‚ ููŠ ุงู„ู€DNA ุงู„ู„ูŠ

715
01:09:31,360 --> 01:09:37,390
ูŠุณู…ูˆู†ู‡ Somatic Rearrangementูู‡ุฐู‡ ุงู„ุธุงู‡ุฑุฉ ูŠุนู†ูŠ

716
01:09:37,390 --> 01:09:43,450
ู…ูƒู„ูุฉ ุฌุฏุงู‹ ูˆุฃู†ุง ู…ุซู„ุงู‹ ู„ู„ู€ B-Lymphocytes ู„ู„ู€

717
01:09:43,450 --> 01:09:46,790
Immunoglobulins ุจูƒูˆู† ุนู†ุฏูŠ Two copies ูˆุงุญุฏ ุนู„ู‰

718
01:09:46,790 --> 01:09:51,930
ูƒุฑูˆู…ูˆุฒูˆู… 14 ู…ู† ุฃุจูˆูŠ ูˆุงุญุฏ ุนู„ู‰ ูƒุฑูˆู…ูˆุฒูˆู… ุชุจุน ุฃู…ูŠ

719
01:09:51,930 --> 01:09:56,930
ุจูŠูƒูˆู† ููŠ ุฃูŠ ุฎู„ูŠุฉ B-Lymphocytes ูˆุงุญุฏ ุดุบู„ุช ู…ุงูŠูƒูˆู†ูˆุด

720
01:09:56,930 --> 01:10:01,170
ุงุซู†ูŠู† ุดุบู„ุช ููŠ ู†ูุณ ุงู„ุฎู„ูŠุฉ ููŠ ุฎู„ุงูŠุฉ ุจุชุดุบู„ ู‡ุฐุง ุงู„

721
01:10:01,170 --> 01:10:05,700
copy ููŠ ุฎู„ุงูŠุฉ ู…ุดุบู„ุฉ ุงู„ copy ุงู„ุชุงู†ูŠุฉุจุงู„ู†ุณุจุฉ ู„ู„ู€

722
01:10:05,700 --> 01:10:10,520
Light ChainุŒ ููŠ ุนู†ุฏู‰ ุฃุฑุจุน ู†ุณุฎ ุจุฑุถู‡ ูˆุงุญุฏ ู…ู† ุงู„ุฃุฑุจุน

723
01:10:10,520 --> 01:10:15,000
ู‡ูŠ ุงู„ู„ูŠ ุดุบู„ู‡ุง ุงู„ู€ ุซู„ุงุซ ุงู„ุซุงู†ูŠุงุชุŒ ูŠุง ุฅู…ุง ู…ุฌุฑุจุงุชุŒ ูŠุง

724
01:10:15,000 --> 01:10:20,260
ุฅู…ุง ู…ุด ู…ุฌุฑุจุงุช ุจุณ ุจุงู„ุฃุฎูŠุฑ ุฃูŠ De-Lymphocyte ู†ุงุฌุญุฉ

725
01:10:20,260 --> 01:10:25,880
ูŠูƒูˆู† ููŠู‡ุง one copy ู„ู€ ุงู„ู€ one ู‚ู„ูŠู„ ู‡ูˆ ุงู„ู„ูŠ ุจุณ ุดุบุงู„

726
01:10:25,880 --> 01:10:31,820
ุงู„ุซุงู†ูŠ ุณุงูƒู†ุŒ ู…ุงููŠุด ุฅู„ู‡ expression ูู‡ูŠ ุธุงู‡ุฑุฉ ู…ูˆุฌูˆุฏุฉ

727
01:10:31,820 --> 01:10:36,610
ูˆุธุงู‡ุฑุฉ ู…ู‡ู…ุฉูˆุจูŠุณู…ูˆู‡ุง ู…ู† ุฎู„ุงู„ ุงู„ู€ Somatic

728
01:10:36,610 --> 01:10:40,830
Rearrangement ูˆู‡ูŠ ุธุงู‡ุฑุฉ ูŠุนู†ูŠ ู…ุชุฃูƒุฏุฉ ู…ู†ู‡ุง ูˆุณู‡ู„ุฉ

729
01:10:40,830 --> 01:10:47,410
ูˆู…ูู‡ูˆู…ุฉ ูŠุนู†ูŠ ููŠู‡ ูƒุงู†ูˆุง ูŠู‚ูˆู„ูˆู„ู†ุง ูˆุฅุญู†ุง ุทู„ุงุจ ุนู„ู‰ ู…ู†

730
01:10:47,410 --> 01:10:52,530
ุฒู…ุงู† ุนู„ู‰ X-chromosome in inactivation ูŠุนู†ูŠ ุจุงู„ู†ุณุจุฉ

731
01:10:52,530 --> 01:11:00,330
ุจุงู„ุฐุงุช ู„ู„ู€Females ู„ู…ุง ุฃู†ุง ุขุฌูŠ ุฃุฏุฑุณ ุงู„ู€ โ€ฆ ู„ู…ุง ุฃู†ุง

732
01:11:00,330 --> 01:11:07,400
ุขุฌูŠ ุฃุฏุฑุณูƒูŠู ุฃู†ู‡ ุงู„ู€ X-Chromosome ุงู„ู„ูŠ ุจูŠุดุชุบู„ ุฑุงุญ

733
01:11:07,400 --> 01:11:12,420
ู†ู„ุงู‚ูŠ ุฅู†ู‡ ูƒู„ ุฎู„ุงูŠุงู‡ุง ุฑุงุญ ูŠู†ู‚ุณู…ูˆุง ูŠุง ุฅู…ุง ุฎู„ูŠุฉ

734
01:11:12,420 --> 01:11:17,220
ุจุชุดุชุบู„ ุนู„ู‰ ุงู„ู€ Chromosome ู…ุซู„ุง X ุชุจุน ุงู„ุฃุจ ุฃูˆ ุงู„ู€

735
01:11:17,220 --> 01:11:22,980
Chromosome ุชุจุน ุงู„ุฃู… ูˆู‡ุฐู‡ ุจุงู„ู€ Early Empyrogenesis

736
01:11:22,980 --> 01:11:27,600
ู…ุงุดูŠุŒ ุธุงู‡ุฑุฉ ุจุชุญุฏุซุŒ ุจุงู„ุชุงู„ุช ุฅุฐุง ู…ุซู„ุง ููŠ ูƒูˆุจูŠ ููŠู‡ุง

737
01:11:27,600 --> 01:11:32,590
ู…ุฑุถ ูˆููŠ ูƒูˆุจูŠ ู…ุงููŠุด ููŠู‡ุง ู…ุฑุถุŒ ู…ุงุดูŠุŸุนู„ู‰ ู…ุณุชูˆู‰

738
01:11:32,590 --> 01:11:38,250
ุงู„ุฌุฒูŠุฆูŠ ุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ู€ ยซุจูŠูˆ ูƒูŠู…ูŠูƒู„ยป ุนู„ู‰ ู…ุณุชูˆู‰ ุฃุฏุฑุณ

739
01:11:38,250 --> 01:11:43,830
ุงู„ู€ ยซRNAยป ูˆุงู„ุจุฑูˆุชูŠู† ุงู„ู…ูˆุฌูˆุฏ ููŠ ุงู„ุฎู„ูŠุฉ ู‡ุฐู‡ ุจูŠู„ุงู‚ูŠู‡

740
01:11:43,830 --> 01:11:49,530
ูƒู„ู‡ ู…ู† ู…ุตุฏุฑ ูˆุงุญุฏ ู…ุด ู…ู† ุงู„ู…ุตุฏุฑูŠู† ููŠ ู†ูุณ ุงู„ุฎู„ูŠุฉ ูู‡ุฐู‡

741
01:11:49,530 --> 01:11:53,950
ุจุฏู†ุง ู†ุณู…ูŠู‡ุง ยซmono-allelic expressionยป ูู‡ูŠ ุธุงู‡ุฑุฉ

742
01:11:53,950 --> 01:12:00,990
ุจุชุญุฏุซ ุงู„ู„ูŠ ุญุงุทูŠู†ุง ู‡ู†ุง ุฃู†ุช ู‡ุฐู‡ ุงู„ุฃุตู„ ุฃู†ุช ู‡ูŠูƒ ู…ูˆุฌูˆุฏ

743
01:12:02,360 --> 01:12:07,820
ูˆุดูƒู„ู‡ุง ุธุงู‡ุฑุฉ ุจุชุญุฏุซ ู„ู€โ€ฆ ูŠุนู†ูŠ ููŠู‡ ู„ู‡ุง Ex

744
01:12:07,820 --> 01:12:16,240
-inactivation center ุญุงุทูŠู†ู‡ ู‡ู†ุง ูุงู„ุฎู„ูŠุฉ

745
01:12:16,240 --> 01:12:24,380
ููŠ ุงู„ู€ Early Epidermogenesis ููŠ ุจุฏุงูŠุฉ ุชุฎู„ู‚ ุงู„ุฎู„ุงูŠุง

746
01:12:24,380 --> 01:12:28,660
ููŠ ุฌุณู… ุงู„ุฅู†ุณุงู† ููŠ ุงู„ู…ุฑุญู„ุฉ ุงู„ุฃูˆู„ู‰ ู„ู…ุง ุนุฏุฏ ุงู„ุฎู„ุงูŠุง

747
01:12:29,240 --> 01:12:39,040
120ุŒ 40ุŒ ูƒุฐุงุŒ ุจุชู… ุงู†ู‚ุณุงู…ู‡ุง ุฃูˆ ุจุชู… ู…ู„ุงุญุธุฉ ุฅู†ู‡ ุจุณ

748
01:12:39,040 --> 01:12:42,200
ู†ุตู‡ุง ูˆุงุญุฏุฉ ู…ู† ุงู„ู€ X-Chromosome ุดุบุงู„ ูˆุงู„ุซุงู†ูŠ

749
01:12:42,200 --> 01:12:46,960
ุจูŠุนุทูŠู†ุง ุงุณู…ู‡ Bar Body ุจูƒูˆู† ู‡ูƒุฐุงุŒ Condensed

750
01:12:46,960 --> 01:12:55,960
ูˆUnactivated ูุงู„ู€ โ€ฆ ู‡ู†ุง ู…ุซู„ุงุŒ ู‡ุฐุง ุชุจุน ุงู„ุฃุจ ุงู„ุดุบุงู„

751
01:12:55,960 --> 01:13:00,350
ูˆู‡ุฐุง ุชุจุน ุงู„ุฃู… ุงู„ู„ูŠ ูƒุงู† ู†ุงูŠู…ุงู„ุฎู„ูŠุฉ ุงู„ุชุงู†ูŠุฉ ุฌู†ุจู‡ุงุŒ

752
01:13:00,350 --> 01:13:06,190
ู„ุฃุŒ ุชุจุน ุงู„ุฃู… ู‡ูˆ ุงู„ู„ูŠ ุดุบุงู„ ูˆุชุจุน ุงู„ุฃุจ ุฃูˆ ุจุงู„ุนูƒุณ ุงู„ู„ูŠ

753
01:13:06,190 --> 01:13:12,010
ู†ุงุนู… ูู€ Serial and clonal maintenance of that gene

754
01:13:12,010 --> 01:13:24,250
ู‡ุฐุง ูŠุนู†ูŠ ุจูŠุนุทูŠู†ุง ุชูุณูŠุฑ ุชุฎูŠู„ ุฃู†ู‡ ุฃู†ุง ุจูุชุฑุถ ู„ูˆ ุฅู†ุณุงู†

755
01:13:24,250 --> 01:13:31,060
ุนู†ุฏู‡ two copiesู„ู„ู€ X-Chromosome ุนู„ูŠู‡ู… ู…ุฑุถ ู…ุนูŠู†

756
01:13:31,060 --> 01:13:37,300
ุงู„ุฃุตู„ ุฅุฐุง ูƒุงู† ุงู„ู€Chromosome ุงู„ูˆุงุญุฏ ุดูุงู„ุŒ ุดูุงู„ ูƒูˆูŠุณ

757
01:13:37,300 --> 01:13:42,680
ูˆุจูŠุนุทูŠู†ุง ุงู„ุงุดูŠ ุงู„ู…ุทู„ูˆุจ ุฃู† ู‡ุฐู‡ ุงู„ู…ุฑุฃุฉ ู…ุด ุจุณ ุฅู†ู‡ุง

758
01:13:42,680 --> 01:13:46,940
ุญุงู…ู„ ุญุงู…ู„ุŒ ู…ู…ูƒู† ุชู†ู‚ู„ ุฅู„ู‰ ุฃุทูุงู„ู‡ุงุŒ ุจุณ ุงู„ุฃุตู„ ู…ุงูŠูƒูˆู†

759
01:13:46,940 --> 01:13:50,800
ุนู†ุฏู‡ุง ู…ุฑุถ ุจุณ ู„ูˆ ู„ู‚ูŠู†ุง ุฏุฑุฌุฉ ุจุณูŠุทุฉ ู…ู† ุงู„ู…ุฑุถุŒ ุดูˆ

760
01:13:50,800 --> 01:13:56,200
ู…ุนู†ุงุชู‡ุŸู…ุนู†ุงุชู‡ ุฅู†ู‡ ุตุงุฑ ููŠ ุฌุฒุก ู…ู† ุงู„ุฎู„ุงูŠุง ููŠ ุฌุณู…ู‡ุง

761
01:13:56,200 --> 01:14:01,560
ูุนู„ุงู‹ ุญุงู…ู„ ู„ูˆ ุจุชุนุฑุถ ุงู„ุฌูŠู† ุฃูˆ ุจุชุนุฑุถ ุงู„ุจุฑูˆุชูŠู† ุฃูˆ

762
01:14:01,560 --> 01:14:07,400
ุจุชุนุฑุถ ุงู„ุฅุดูŠ ุงู„ู„ูŠ ุนุงู…ู„ ุงู„ู…ุดูƒู„ุฉ ูˆุจุงู„ุชุงู„ูŠ ูุจุชูƒูˆู†

763
01:14:07,400 --> 01:14:12,320
ุนู†ุฏู‡ุง ู†ุณุจุฉ ู…ู† ุงู„ู…ุฑุถ ุฃุฎู ู…ุด ู…ู‚ุงุฑู†ุฉ ุฒูŠ ุงู„ุฐูƒุฑ ุงู„ู„ูŠ

764
01:14:12,320 --> 01:14:16,020
ุจูŠูƒูˆู† ุจุณ ยซ1Xยป ูˆุฏู‡ disease ุจูŠูƒูˆู† Catastrophic ูŠุนู†ูŠ

765
01:14:16,020 --> 01:14:20,500
ุฅุดูŠ ู‚ูˆูŠ ูƒุซูŠุฑ ุจุณ ู…ุงุจุชูƒูˆู†ุด Normal ุฒูŠ ุงู„ุฅู†ุณุงู† ุงู„ุนุงุฏูŠ

766
01:14:22,650 --> 01:14:28,970
ูู‡ุฏูˆู„ุฉ ุถุงู‡ุฑุชูŠู† ุณู‡ู„ุงุช Random Allelic Silencing ุฃูˆ

767
01:14:28,970 --> 01:14:33,610
Activation ุฃูˆ Genomic Imprinting ุจุงู„ุฃุฎูŠุฑุŒ ู‡ุฏูˆู„ุฉ

768
01:14:33,610 --> 01:14:37,570
Epigenetic Details

769
01:14:37,570 --> 01:14:43,290
ุฃู†ุง ูˆุงู„ู„ู‡ ูŠุนู†ูŠุŒ ุจุงู„ุฐุงุช ุนู„ู‰ ู‡ุฏูˆู„ุฉ ุงู„ุทูˆุงู‡ุฑ ูŠุนู†ูŠ ู…ุด

770
01:14:45,390 --> 01:14:50,470
ูŠุนู†ูŠ ู…ุด aware ุงู„ุขู† ุนู„ู‰ ุดูˆ ุงู„ุญุงู„ุฉุŒ ุดูˆ ุงู„ู…ุฑุถ ุดูˆ

771
01:14:50,470 --> 01:14:56,830
ุงู„ุฃุดูŠ ุงู„ู„ูŠ ุจุญูƒูˆุง ุนู†ู‡ ุจุณ ูŠุนู†ูŠ ุจุงู„ุฃุฎูŠุฑ ูŠุนู†ูŠ ุงู„ุฑุณุงู„ุฉ

772
01:14:56,830 --> 01:15:05,070
ุงู„ู„ูŠ ุจุฏู†ุง ุฅูŠุงู‡ุง ุฃู†ู‡ ุฃู†ุง ุนู†ุฏูŠ ุฃูƒุชุฑ ุฃุญูŠุงู†ู‹ุง one pair

773
01:15:05,070 --> 01:15:11,190
ุฃุญูŠุงู†ู‹ุง ุฃูƒุชุฑ ู…ู† ู†ูุณ ุงู„ู€Gene ูˆุญุชู‰ ู„ูˆ ุนู†ุฏูŠ ุฃูƒุชุฑ ู…ู†

774
01:15:11,190 --> 01:15:19,810
pair ู‡ู†ุงูƒู„ุณุฉ ูƒู…ุงู† ุฏุฑุฌุฉ ู…ู† ุงู„ุชุนู‚ูŠุฏ ููŠ ุฅู†ู‡ ูƒู…ูŠุฉ ุงู„ู€

775
01:15:19,810 --> 01:15:26,850
Transcription ุฅู†ู‡ ุดูˆ ุฏุฑุฌุฉ ุงู„ุดุบู„ ู„ูˆ ูƒุงู†ุŒ ูŠุนู†ูŠ ู‡ุณุฉ

776
01:15:26,850 --> 01:15:30,830
ุตุญูŠุญ ููŠู‡ ุฌูŠู†ุงุช ู…ุนูŠู†ุฉ ููŠ ุฎู„ุงูŠุง ู…ุนูŠู†ุฉุŒ ุจุฏูƒ ุฅูŠู‡ุŸ Red

777
01:15:30,830 --> 01:15:34,370
blood cell ุจุฏู‡ุง ุงู„ู€ Hemoglobin ู…ุซู„ุงู‹ ุงู„ู€

778
01:15:34,370 --> 01:15:36,530
Immunoglobin ุฃูˆ ุงู„ู€ B-Lymphocyte ุจุฏู‡ุง ุงู„ู€

779
01:15:36,530 --> 01:15:40,230
Immunoglobin ุฌูŠู† ูŠุดุชุบู„ ุจุณุŒ ุทุจ ุฃู†ุง ุนู†ุฏูŠ ุฃูƒุชุฑ ู…ู†

780
01:15:40,230 --> 01:15:45,600
ุฎูŠุงุฑุŒ ุดูˆ ุจุดุชุบู„ุŸุนู†ุฏู‰ Two copies ุจูŠุดุชุบู„ูˆุง ุชู…ุงู…ุง ุฒู‰

781
01:15:45,600 --> 01:15:52,080
ุจุนุถ ุฃุญูŠุงู†ุง ู†ุนู… ุจุณ ููŠ ุฎู…ุณ ู„ุนุดุฑูŠู† ุจุงู„ู…ูŠุฉ ู…ู† ุงู„ู€

782
01:15:52,080 --> 01:15:58,080
Autosomal Genes ุจูŠุตูŠุฑ Unbalanced ู…ู…ูƒู† ุชูˆุตู„ ุฅู†ู‡

783
01:15:58,080 --> 01:16:02,480
Monoallelic Expression ุฅู†ู‡ 100% ู…ู† ู…ุตุฏุฑ ุงู„ู…ุตุฏุฑ

784
01:16:02,480 --> 01:16:09,910
ุงู„ุชุงู†ูŠ ุงู„ู…ุงุฆู„ ูˆุฏุฎู„ ูˆู…ู…ูƒู† ูŠูƒูˆู†ู†ุณุจ ุฃู‚ู„ ู…ุชูุงูˆุชุฉ ู…ุง

785
01:16:09,910 --> 01:16:13,950
ุจูŠู† ุฎู…ุณูŠู† ุจุงู„ู…ูŠุฉ ูˆุฎู…ุณูŠู† ุจุงู„ู…ูŠุฉ ูˆู…ูŠุฉ ุจุงู„ู…ูŠุฉ ูˆุตูุฑ

786
01:16:13,950 --> 01:16:19,750
ููƒู„ ุงู„ุธูˆุงู‡ุฑ ุงู„ู„ูŠ ุจุชุชูƒู„ู… ุนู†ู‡ุง ู‡ูŠ ุจู†ุณู…ูŠู‡ุง Epigenetic

787
01:16:19,750 --> 01:16:27,050
Influences Epigenetic Control ู…ุงุดูŠ ูˆุงู„ุณุจุจ ู…ู† ู„ูŠุด

788
01:16:27,050 --> 01:16:31,030
ุจู†ุณู…ูŠู‡ Epigenetic ู…ุด Genetic ู„ุฃู†ู‡ ุงู„ู€Gene ู†ูุณู‡

789
01:16:31,030 --> 01:16:34,290
ุงู„ู€Gene ู…ุง ุชุบูŠุฑุด ุงู„ู€Gene ู‡ูˆ ุงู„ู„ูŠ ุจุฏูŠ ูŠุนุทูŠู†ุง

790
01:16:34,290 --> 01:16:39,950
ุงู„ุจุฑูˆุชูŠู† ู‡ุฐุง ู„ุณู‡ุจูŠู†ู‡ู… ู…ุง ููŠุด ู‡ุงู„ูุฑู‚ุŒ ูŠุนู†ูŠ ู…ุง ูƒุงู†ุด

791
01:16:39,950 --> 01:16:45,790
ููŠู‡ ูุฑู‚ ู†ุงุชุฌ ุนู† ุงู„ุฌูŠู† ู†ูุณู‡ุŒ ููŠ ุฃุณุฆู„ุฉุŸ ุฏูƒุชูˆุฑุŒ ููŠ

792
01:16:45,790 --> 01:16:52,050
ุณุคุงู„ุŒ ุจุณ ุฃุฎูŠุฑ ู…ู† ุงู„ุฏูƒุชูˆุฑุฉุŒ ุฃุนุชู‚ุฏุŒ ุจุฎุตูˆุต ุงู„ู€Clonal

793
01:16:52,050 --> 01:16:56,270
Maintenance ุจุนุฏ ู…ุง ูŠุตูŠุฑ ุนู…ู„ูŠุฉ ุงู„ู€Clonal

794
01:16:56,270 --> 01:17:02,010
Maintenance ู…ุนู†ุงุชู‡ ุฃู†ู‡ ุฅุฐุง ุจุฏุช ุจุดูƒู„ ู…ุนูŠู†ุŒ ุจุชูƒู…ู„

795
01:17:02,010 --> 01:17:07,750
ุจู‡ุฐุง ุงู„ุดูƒู„ุŒ ู…ุงุดูŠุŸูŠุนู†ูŠ ุจูŠุตูŠุฑ ุฌูˆุง ุฌุณู… ุงู„ุฅู†ุณุงู†

796
01:17:07,750 --> 01:17:14,190
ู…ุฌู…ูˆุนุชูŠู† ู…ู† ุงู„ุฎู„ุงูŠุง ุจุงู„ู†ุณุจุฉ ู„ู‡ุฐุง ุงู„ู€GeneุŒ ู…ุงุดูŠุŸ

797
01:17:14,190 --> 01:17:20,750
ูŠุนู†ูŠ ู†ุฎุชุฑุถ Chromosome ู…ุนูŠู† ุฃูˆ ุงู„ู€X-Chromosome

798
01:17:20,750 --> 01:17:27,070
ู…ุซู„ุงุŒ ุงู„ู„ูŠ ุญุทูŠู†ุง ุนู„ูŠู‡ ู‚ุจู„ ุดูˆูŠุฉ ุงู„ุขู†ุŒ

799
01:17:27,070 --> 01:17:32,590
ุฅู…ุง ู‡ุนู…ู„ ู…ุซู„ุง ู†ู‚ูˆู„ ุจุงู„ู€G6PD Deficiencyู…ุงุดูŠุŒ ููŠู‡

800
01:17:32,590 --> 01:17:38,530
ุงู„ู€G6PD ุงู„ู€โ€ฆ ุงู„ู€Enzyme ู‡ุฐุง ููŠู‡ ุนู„ู‰ ุงู„ู€X-Chromosome

801
01:17:38,530 --> 01:17:49,310
ูˆููŠู‡ ู…ุฑุถ ูุณโ€ฆ ุงู„ู€โ€ฆ ุงู„ู€โ€ฆ ุงู„ู€โ€ฆ ุงู„ู€โ€ฆ ู„ู…ุง ู†ุชูƒู„ู… ุนู† ุดูˆ

802
01:17:49,310 --> 01:17:57,530
ุงุณู…ู‡ุŸ ุงู„ู€โ€ฆ ุงู„ู€โ€ฆ ุงู„ุฎู„ุงูŠุง ุชุจุนุช ุงู„ู€โ€ฆ ุงู„ู€โ€ฆ ุงู„ู„ูŠ ุจุธู†

803
01:17:57,530 --> 01:18:05,840
ุงู„ูˆุงุญุฏ ุฅุฐุง ูƒุงู†ุจุฏูŠุช ุฅู†ุณุงู† ุฐูƒุฑ ูˆู‚ุนุฏุช ุฃูุญุต ููŠ ุงู„ู€

804
01:18:05,840 --> 01:18:12,380
ยซexpressionยป ุชุจุน ู‡ุฐุง ุงู„ู€ ยซุฌูŠู†ยปุŒ ู…ุงุดูŠุŸ ุจู„ุงู‚ูŠ ุฅู† ูƒู„

805
01:18:12,380 --> 01:18:17,940
ุฎู„ุงูŠุง ู…ุด ู‚ุงุฏุฑุฉ ุชุนู…ู„ ุงู„ู€ ยซุจุฑูˆุชูŠู†ยป ุงู„ู„ูŠ ุฃู†ุง ุจุฏูŠู‡ุงุŒ

806
01:18:17,940 --> 01:18:23,700
ุจุณ ููŠ ู…ุฑุญู„ุฉ ู…ุจูƒุฑุฉ ููŠ ุญูŠุงุฉ ุงู„ุฃู†ุซู‰ุŒ ุจูƒูˆู† ุฃู†ุง ุนู†ุฏูŠ

807
01:18:23,700 --> 01:18:28,540
two copiesุŒ ุจุณ ู…ุงูŠุตูŠุฑ ุฃุซู†ูŠู†ู‡ู… ูŠุดุชุบู„ูˆุง ุฃุญูŠุงู†ู‹ุงุจุชูƒูˆู†

808
01:18:28,540 --> 01:18:33,500
ุฅู†ู‡ ู„ู‡ุฐุง ู„ุบุฑุถ ุงู„ุฌูŠู† ู…ุนูŠู† ู„ุณุจุจ ู…ุนูŠู† ู„ุดุบู„ ู…ุนูŠู†ุฉ

809
01:18:33,500 --> 01:18:39,380
ุจุชู„ุงู‚ูŠ ุจุณ ู†ุณุฎุฉ ูˆุงุญุฏุฉ ุงุดุชุบู„ุช ูููŠ ู…ุฑุญู„ุฉ ู…ุนูŠู†ุฉ ูŠู…ูƒู†

810
01:18:39,380 --> 01:18:45,340
ูŠูƒูˆู† ู…ุด 100%ุŒ 50%ุŒ 50% ุฎู„ุงูŠุง ุดุบู„ุช ู‡ุฐุง ุงู„ุฌูŠู† ูˆุฎู„ุงูŠุง

811
01:18:45,340 --> 01:18:50,540
ุดุบู„ุช ู‡ุฐุง ุงู„ุฌูŠู† ูŠู…ูƒู† ู…ุซู„ุง 20%ุŒ 80% ุฅุดูŠ ุดุบู„ ู‡ุฐุง

812
01:18:50,540 --> 01:18:57,760
ุงู„ุฌูŠู† ูˆ80% ุดุบู„ ุงู„ุฌูŠู† ุงู„ุชุงู†ูŠ ุงู„ู€20% ุจูŠุธู„ูˆุง 20%ูƒู„ ู…ุง

813
01:18:57,760 --> 01:19:04,640
ุจู†ู‚ุณู…ู‡ ุจูŠุธู„ู‡ู… ู†ูุณู‡ู… ู…ู† ู†ุงุญูŠุฉ ุชุดุบูŠู„ู‡ู… ู„ุฃูŠ ู†ุณุฎุฉ ู…ู†

814
01:19:04,640 --> 01:19:10,420
ุงู„ู€ X-Chromosome ูˆุงู„ู…ุฌู…ูˆุนุฉ ุงู„ุซุงู†ูŠุฉ ุจุชุธู„ ุชุดุบู„ ู†ูุณ

815
01:19:10,420 --> 01:19:18,000
ุงู„ู€G ูŠุนู†ูŠ ู‡ุฐู‡ ุฎุงุตูŠุฉ ุชุธู„ ุชูˆุฑุซ ููŠ ุงู„ุฎู„ุงูŠุง ุงู„ู†ุงุชุฌุฉ ุนู†

816
01:19:18,000 --> 01:19:22,960
ุงู†ู‚ุณุงู… ุงู„ุฎู„ูŠุฉ ุงู„ู„ูŠ ุธู‡ุฑุช ููŠู‡ุง ู‡ุฐู‡ ุงู„ู†ุงุญูŠุฉุŒ ูˆุงุถุญุŸ

817
01:19:25,080 --> 01:19:29,560
ุทุจุนู‹ุงุŒ ุฏูƒุชูˆุฑุŒ ุจุณ ุซุงู†ูŠ ู…ู† ุงู„ู€ ุฃูˆ ุงู„ู†ู‚ุทุฉ ูŠุนู†ูŠ ุงู„ุญุงุจุจ

818
01:19:29,560 --> 01:19:32,900
ุงู„ูƒุฑูŠู… ุฃู†ู‡ ุงุชูˆุถุญ ุฃู†ู‡ ุนู…ุฑู‡ ูŠุฎุฏ ุงู„ู€ chromosomal

819
01:19:32,900 --> 01:19:36,980
domain ุงู„ู„ูŠ ุญูƒูŠู†ุง ุนู†ู‡ ู‚ุจู„ ุดูˆูŠุฉ ููŠู‡ ู…ูƒุงู† ู„ู„ู†ู‚ุทุฉ ุฏูŠ

820
01:19:36,980 --> 01:19:42,880
ูŠุนู†ูŠ ู…ุง ู„ู‡ุง ุงู„ chromosomal domainุŸ ุจุฏู‡ ุชุนูŠุฏ ุจุณ

821
01:19:42,880 --> 01:19:47,340
ุงู„ู†ู‚ุทุฉ ูŠุนู†ูŠ ุฃูˆ ุงู„ุดุฑุญ ุฅู„ู‡ุง ูŠุนู†ูŠ ุฅูŠุด ู‡ูŠ ุฃูˆ ุชุทู„ุน ูŠุนู†ูŠ

822
01:19:47,340 --> 01:19:52,040
ูŠุนู†ูŠุŒ ูŠุนู†ูŠ ู…ุง ุชุฃุฎุฏูˆุด ุงู„ู…ูˆุงุถูŠุน ูƒุซูŠุฑุฉุŒ ู…ุงุดูŠุŒ ุงุญู†ุง

823
01:19:52,040 --> 01:19:57,490
ุจู‡ู…ู†ุงุงู„ุดูŠุก ุจุงู„ุฐุงุช ุฅุฐุง ุฅู„ู‡ ุชุทุจูŠู‚ ุณุฑูŠุฑูŠ ุฅุฐุง ุฅู„ู‡

824
01:19:57,490 --> 01:20:09,290
ุฃู‡ู…ูŠุฉ ุญุชู‰ ุฃู‚ุฏุฑ ุฃู†ุณุฎ ูˆุฃุนู…ู„ Transcription ู„ู€DNA ุจุฏูŠ

825
01:20:09,290 --> 01:20:16,410
ุญุจู„ ุงู„ุบุณูŠู„ุŒ ุญุจู„ ุณู„ูƒ ุงู„ุบุณูŠู„ ูŠูƒูˆู† ุงู„ู…ูุฑูˆุถ ุฅุฐุง ู…ู„ููˆู

826
01:20:16,410 --> 01:20:21,860
ูƒุซูŠุฑ ูƒุซูŠุฑ ูƒุซูŠุฑ ู…ุงุนุฑูุด ุฃุณุชุฎุฏู…ู‡ุŒ ูˆุงุถุญุŸูโ€ฆ ุตุญูŠุญ ูˆ ุฃู†ุง

827
01:20:21,860 --> 01:20:24,700
ุฏูƒุชูˆุฑ ุจุฑุถู‡ ูŠุนู†ูŠ ุจุฑูƒุฒ ุนู„ู‰ ู‡ุฐู‡ ุงู„ู†ู‚ุทุฉ ูŠุนู†ูŠ ู‚ุถูŠุฉ ุงู†ู‡

828
01:20:24,700 --> 01:20:30,040
ูŠุนู†ูŠ ู…ุง ุชุณุฃู„ูˆุด ุนู† ุฃุดูŠุงุก ูŠุนู†ูŠ ุนุดุงู† ู…ุง ุชุณูŠุฑูŠุด ู…ุทู„ูˆุจ

829
01:20:30,040 --> 01:20:33,440
ู…ู†ูƒูˆุง ูŠุนู†ูŠ ู‚ุถูŠุฉ ุงู„ุฏูƒุชูˆุฑ ู…ุนุชุฒ ุจุฑุถู‡ ุจูŠุณุฃู„ ุนู† ุงู„ู€

830
01:20:33,440 --> 01:20:38,000
ยซุฎุฏู‡ุง ุจุจุณุงุทุฉยป ยซุฎุฏู‡ุง ุจุจุณุงุทุฉยป ูŠุนู†ูŠ ุงู„ุฏูƒุชูˆุฑ ู…ุนุชุฒ ุจุฑุถู‡

831
01:20:38,000 --> 01:20:41,360
ุจูŠุณุฃู„ ุนู† ยซGenomic Imprintingยป ุงู„ุฏูƒุชูˆุฑ ุทุจ ูŠุนู†ูŠ ู…ุง

832
01:20:41,360 --> 01:20:45,280
ุนุฑุด ุญุงุฌุงุชู‡ ู„ูˆ ูุฑู‚ุชู‡ ุฃู†ุง ุจู‚ูˆู„ูƒ ู‡ูŠ ู†ูˆุน ู…ู† ุงู„ู€ ูŠุนู†ูŠ

833
01:20:45,280 --> 01:20:49,380
ู†ูˆุน ู…ู† ุงู„ู€ Epigenetic Mechanisms ุจุณ ููŠ ู…ู„ุงุญุธุฉ ูŠุนู†ูŠ

834
01:20:49,380 --> 01:20:55,440
ุจุฏูƒู… ุชูู‡ู…ูˆุง ุดุบู„ุชุงู„ูƒุชุงุจ ู‡ุฐุง ู…ุน ุฃู†ู‡ ู…ู…ุชุงุฒ ูˆ up to

835
01:20:55,440 --> 01:21:02,020
date ูˆู…ู‡ู… ูˆูƒูˆูŠุณุŒ ุจุณ ู…ุด ู‚ุฑุขู†ุŒ ู…ุด ุญู‚ูŠู‚ุฉ ู…ุทู„ู‚ุฉุŒ ู…ุด

836
01:21:02,020 --> 01:21:09,160
ุฅุดูŠ ูŠุนู†ูŠ ูŠู…ูƒู† ุจุนุฏ ู†ุณุฎุชูŠู† ู…ู† ุงู„ูƒุชุงุจ ูŠุดูŠู„ูˆู‡ุง ูƒู„ู‡ุง

837
01:21:09,900 --> 01:21:14,180
ูŠุนู†ูŠ ุงู„ู€ Genetic Imprinting ู‡ุฐู‡ ุฅุฐุง ุจุฏูŠ ุฃุฏุฎู„ ููŠู‡ุง

838
01:21:14,180 --> 01:21:22,140
ูŠุนู†ูŠ ู‡ูŠ ุชูุณูŠุฑุŒ ู‡ูŠ ู…ู„ุงุญุธุฉ ุจุชุนุฑููˆุง ูŠุนู†ูŠ ูƒู„ู…ุฉ ู†ุธุฑูŠุฉุŒ

839
01:21:22,140 --> 01:21:26,680
ุดูˆ ูŠุนู†ูŠ ู†ุธุฑูŠุฉุŸ ู†ุธุฑูŠุฉ ู‡ูŠ ุชูุณูŠุฑ ู‚ุงุจู„ ุฅู† ูŠูƒูˆู† ุตุญ ุฃูˆ

840
01:21:26,680 --> 01:21:32,410
ุฎุทุฃู…ุง ููŠ ุดูŠุก ู…ุทู„ุจุŒ ู‡ูŠูƒ ุฃู†ู‡ ุจุณ ู„ู…ุง ู†ุญูƒูŠ ุนู† ูŠุนู†ูŠ

841
01:21:32,410 --> 01:21:37,510
ุธุงู‡ุฑุฉ ุจุชุญุฏุซ ูˆุฃู†ุง ุจูุณุฑู‡ุง ุจุดูƒู„ ู…ุนูŠู† ุฃู†ุง ุจุญุงูˆู„ ุฃู†ู‡ ุฃูˆ

842
01:21:37,510 --> 01:21:44,130
ุฃู†ุง ุจุชุฏุนูŠ ูˆุงู„ูˆุงุญุฏ ุจุฏู‡ ูŠุฏุนูŠ ู‡ูŠูƒ ุฃู†ู‡ ู‡ุฐุง ู‡ูˆ ุงู„ุชูุณูŠุฑ

843
01:21:44,130 --> 01:21:50,270
ุงู„ุญู‚ูŠู‚ูŠ ู„ุฃู†ู‡ ุงู„ุธุงู‡ุฑุฉ ุงู„ุฅูู„ุงู†ูŠุฉ ุญุฏุซุช ุจุณ ู…ู…ูƒู† ุจุนุฏูŠู†

844
01:21:50,270 --> 01:21:53,950
ู†ูƒุชุดู ุฃู†ู‡ ุงู„ูƒู„ุงู… ู‡ุฐุง ุบู„ุท ูˆุจุนุฏูŠู† ูŠุนู†ูŠ ูŠุทู„ุน ุฃู†ู‡

845
01:21:53,950 --> 01:21:58,700
ู…ุงู„ูˆุด ู‚ูŠู…ุฉ ูƒุชูŠุฑุŒ ู‡ุงูŠ ู…ู† ู†ุงุญูŠุฉูˆุงู„ู†ุงุญูŠุฉ ุงู„ุซุงู†ูŠุฉ ุงู„ู„ูŠ

846
01:21:58,700 --> 01:22:05,700
ู‡ูŠ ุฃู†ู‡ ูŠุนู†ูŠ ุญุณุจ ุงู„ุฃุฏูˆุงุช ุงู„ู„ูŠ ุนู†ุฏู‡ุง ุญุณุจ ุงู„ุฅู…ูƒุงู†ุงุช

847
01:22:05,700 --> 01:22:09,220
ุงู„ู„ูŠ ุนู†ุฏู‡ุง ูŠุนู†ูŠ ุฃู†ุง ู„ู…ุง ู†ุตูŠุฑ ุนู†ุฏูŠ ุฅู…ูƒุงู†ุงุช ุฃูƒุซุฑ

848
01:22:09,220 --> 01:22:15,400
ูˆุฃุฏู‚ ุจู‚ูˆู„ ุจู‚ุฏุฑ ุฃุณูˆูŠู‡ุง ูุงู„ู€ Imprinting ุตุฑุงุญุฉ ูŠุนู†ูŠ

849
01:22:15,400 --> 01:22:20,480
ููŠู‡ ุธุงู‡ุฑุฉ ุจู‚ุฑุงู‡ุง ุงู„ู€ Epigenetics ู…ุนู‚ุฏุฉ ุงู„ู€

850
01:22:20,480 --> 01:22:24,140
Epigenetics ูƒู„ู‡ุงุŒ MechanismsุŒ ูƒูŠู ุจุชุชู…ุŒ ูˆุดูˆ ู‡ูŠ

851
01:22:25,580 --> 01:22:33,600
ุจุฏู‘ุนูŠ ุฅู†ู‡ ู„ู„ุขู† ู…ุง ุญุฏุง ุนู†ุฏู‡ ุฃุฏูˆุงุช ุงู†ุนุฏู„ ุงู„ู€

852
01:22:33,600 --> 01:22:41,640
Epigenetics ู…ุงุดูŠุŒ ูู‡ูŠ ุธูˆุงู‡ุฑ ู‡ูŠูƒ ุชุธู† ู‡ูŠูƒ ุงู„ู†ุธุฑูŠุฉ

853
01:22:41,640 --> 01:22:50,080
ุงู„ุนุงู„ูŠุฉ ุงู„ู…ู‚ุจูˆู„ุฉ ุงู„ู„ูŠ ู‡ูŠ ูŠุนู†ูŠ ุฅู†ู‡ุง ูŠุนู†ูŠ ุงู„ุชูุณูŠุฑ

854
01:22:50,080 --> 01:22:55,950
ุงู„ุฃู‚ุฑุจ ู„ู„ุตุญุฉ ู†ุนุชุจุฑู‡ ุจู‡ุฐุง ุงู„ุดูƒู„ุจุณ ูŠุนู†ูŠ ุฃู†ุง

855
01:22:55,950 --> 01:23:01,070
ู…ุงูู‡ู…ุชู‡ุงุด ูƒุซูŠุฑ ู…ุด ูƒุฏู‡ุŒ ู‚ูˆู„ุชู„ูƒู… ุฃู†ุง ู…ุงุนู†ุฏูŠุด ุฃู…ุซู„ุฉ

856
01:23:01,070 --> 01:23:05,910
ูŠุนู†ูŠ ุงู„ู„ูŠ ู‡ูŠ ุชูุณุฑู‡ุง ุฒูŠ ู…ุซู„ุง ุจุงู„ู†ุณุจุฉ ู„ู„ู€ B-cells

857
01:23:05,910 --> 01:23:09,530
ูˆุงู„ู€ Immunoglobulin ุงู„ู€Genes ูˆูƒูŠู ุจุชุนุงู…ู„ ุงู„ุฌุณู…

858
01:23:09,530 --> 01:23:13,170
ู…ุนุงู‡ู… ูˆูƒูŠู ุงุฎุชู„ุงูุงุช ุงู„ู€ B-Lymphocytes ูˆูƒูŠู ูƒุฏู‡

859
01:23:13,170 --> 01:23:17,690
ูˆูƒูŠู ูƒุฏู‡ ูู‡ูŠ ุจุชุนุชู…ุฏ ุนู„ู‰ ุฅู†ูƒ ูŠูƒูˆู† ุนู†ุฏูƒ ุขู„ุงุช ุฃูˆ

860
01:23:17,690 --> 01:23:23,310
ุฃุฏูˆุงุช ูˆุชูƒูˆู† ุชุฏูˆุฑ ุนู„ู‰ ุฅุดูŠ ู…ุนูŠู† ูˆุชุณุชููŠุฏ ู…ู†ู‡ุจุณ ู‡ูŠ

861
01:23:23,310 --> 01:23:30,110
ู†ุธุฑูŠุงุช ุจู‚ูˆู„ูƒ ููŠู‡ ุฅุดูŠ ุฒูŠ ู‡ูŠูƒ ู…ุงุดูŠ ููŠู‡

862
01:23:30,110 --> 01:23:36,070
ูŠุนู†ูŠ ู‡ูŠูƒ ุจุชุฏุฎู„ูˆู†ุง ุจุฅุดูŠ ูŠุนู†ูŠ ู…ู…ูƒู† ู†ุทูˆู„ ูˆู…ุด ุฑุงุญ

863
01:23:36,070 --> 01:23:40,390
ุฃุนุชุจุฑู‡ ุฏุงุฎู„ ู„ุฃู†ู‡ ุฃู†ุง ู…ุด ู…ุชุฃูƒุฏ ู…ู†ู‡ ููŠู‡ ุจูŠู‚ูˆู„ูƒ ู„ูŠุด

864
01:23:40,390 --> 01:23:45,930
ุจุฑุงุกุฉ ุงู„ุฑุญู… ูˆู„ูŠุด ุงู„ุฅู…ุฑุฃุฉ ุงู„ู…ุทู„ู‚ุฉ ูˆ ู„ุง ุงู„ุฅู…ุฑุฃุฉ

865
01:23:45,930 --> 01:23:51,620
ุงู„ู…ุงุช ุนู†ุฏ ุฒูˆุฌู‡ุง ุงู„ุฃุฑู…ุงู„ูŠู„ุงุฒู… ุชู…ุชู†ุน ูƒุฏุง ุนู† ุงู„ุฒูˆุงุฌ

866
01:23:51,620 --> 01:24:02,480
ู„ุฃู†ู‡ ููŠู‡ ูŠุนู†ูŠ ููŠู‡ ุฃุฎุชุงู…ุŒ ููŠู‡ ุชุฃุซูŠุฑุงุช ููŠ ุฌุณู… ุงู„ู…ุฑุฃุฉ

867
01:24:02,480 --> 01:24:09,200
ู…ู† ุฒูˆุฌู‡ุงุŒ ู…ุงุดูŠ ูˆุฃุญูŠุงู†ู‹ุง ู‡ุฐู‡ ุงู„ุดุบู„ุงุช ุจุชุชู… ุชูˆุฑูŠุซู‡ุง

868
01:24:09,200 --> 01:24:15,210
ูŠุนู†ูŠุŒ ุฏู‡ ุจุชุชุฐูƒุฑูˆุงุŒ ูŠุนู†ูŠ ู‡ูŠ ุฅุดูŠ ุจุนุฑูู‡ุงู„ู€MHC

869
01:24:15,210 --> 01:24:18,710
MoleculesุŒ ุงู„ู€Antibodies ุงู„ู„ูŠ ูƒู†ุง ู†ุณุชุฎุฏู…ู‡ู… ุนุดุงู†

870
01:24:18,710 --> 01:24:23,090
ู†ุนุฑู ุดูˆ ุงู„ู€Type ุชุจุน ุงู„ู€HLAุŒ ุงู„ู€Typing ูˆูƒุฐุง ู…ู†

871
01:24:23,090 --> 01:24:29,290
ุงู„ู†ุณุงุกุŒ ุงุชุฒูˆุฌูˆุง ุฑุฌุงู„ ูƒุซูŠุฑูŠู† ูŠุนู†ูŠ ุจุชู„ุงู‚ูŠู‡ุง ุนู†ุฏู‡ุง

872
01:24:29,290 --> 01:24:34,930
ุฏู…ู‡ุง ููŠู‡ Antibodies ุจุดูƒู„ ู…ุนูŠู† ูŠุนู†ูŠ ูุฅู†ู‡ุง ุชุชุฑูƒ ุจุตู…ุฉ

873
01:24:34,930 --> 01:24:38,210
Imprinting ูŠุนู†ูŠ ุงู„ุจุตู…ุฉ ุงู„ูˆุฑุงุซูŠุฉุŒ ู‡ูˆ ุฃู†ุง ุจุฏู†ุง

874
01:24:38,210 --> 01:24:43,270
ู†ุณู…ูŠู‡ุง ุฃูŠู‡ ูƒุฏู‡ ุฃุณุณ ุฃู†ุง ุจูู‡ู…ู‡ุงุฎู„ู‘ูŠู†ุง ู‡ูŠูƒ ู†ุงุฎุฏู‡ุง

875
01:24:43,270 --> 01:24:53,390
ุงู„ุจุณุงุทุฉ ุฅู†ู‡ ุนุจุงุฑุฉ ุนู† ู‚ุงู„ูŠุฉ ู„ู„ุชุญูƒู… ุฃู†ู‡ copy ู…ู† ุงู„ู€

876
01:24:53,390 --> 01:25:00,130
DNA ุงู„ู„ูŠ ุจุชุชู… ุชุดุบูŠู„ู‡ ุงู„ุฌุณู… ูˆุงู„ุฎู„ุงูŠุง ู…ุชู†ูˆุนุฉ ุฌุฏุงู‹

877
01:25:00,130 --> 01:25:05,170
ููŠู‡ ุฎู„ุงูŠุง ูƒู„ู‡ุง ุชุดุชุบู„ ุงู„ู€ two couples ุฒูŠ ุจุนุถ

878
01:25:05,170 --> 01:25:11,350
ูˆุดุบุงู„ูŠู† ุงุซู†ูŠู† ู…ุน ุงุฎุชู„ุงูู‡ู… ุนู† ุจุนุถ ุจู†ุณุจุฉ 50% ูˆ50%

879
01:25:12,280 --> 01:25:15,640
ูˆุงู„ู…ุซุงู„ ุงู„ู„ูŠ ุญุทูŠู†ุงู‡ ุนู„ู‰ ู…ุณุชูˆู‰ ุฅู†ูƒ ุฏุฑุณุชู‡ ุนู„ู‰ ู…ุณุชูˆู‰

880
01:25:15,640 --> 01:25:19,560
ุงู„ู€ RNA ู„ุณู‡ ู…ุด ุนู„ู‰ ู…ุณุชูˆู‰ ุงู„ุจุฑูˆุชูŠู† ูŠู…ูƒู† ุงู„ุจุฑูˆุชูŠู†

881
01:25:19,560 --> 01:25:22,760
ูŠุทู„ุน ุฅู†ู‡ ู…ุงููŠุด ูุฑู‚ ุจูŠู†ู‡ู… ุนู„ู‰ ุงู„ู€ SNP ุงู„ู„ูŠ

882
01:25:22,760 --> 01:25:29,780
ุญุทูˆู†ุงูŠุงู‡ู… ุฃู…ุง ุงู„ุฃู…ุซู„ ุงู„ุซุงู†ูŠ ุนุจุงุฑุฉ ุนู† ููŠู‡ ุชูุงูˆุช ุฅู†ู‡

883
01:25:29,780 --> 01:25:36,760
ุงู„ู†ุณุฎุชูŠู† ู…ู† ุงู„ู€ DNA ู„ุง ูŠุชู… ู‚ุฑุงุกุชู‡ู… ุจุดูƒู„ ู…ุชุณุงูˆูŠุŒ

884
01:25:36,760 --> 01:25:41,390
ูˆุงุถุญุฉุŸุนุดุงู† ุจุฑุถู‡ ูŠุง ุฏูƒุชูˆุฑ ุจุนุฏ ุฃุฐู†ูƒ ูŠุนู†ูŠ ุนุดุงู† ูŠุนู†ูŠ

885
01:25:41,390 --> 01:25:48,130
ูƒู†ู‚ุทุฉ ุฃุฎูŠุฑุฉ ูŠุนู†ูŠูŠุนู†ูŠ ุซุจุชู‡ุง .. ูŠุนู†ูŠ ุงู„ู€ chapter ุฒูŠ

886
01:25:48,130 --> 01:25:52,050
ู…ุง ุญูƒุช ุชุณุฃู„ ูŠุนู†ูŠ ู‡ุฏูŠุฑ ูŠุนู†ูŠ ุงู„ chapter ููŠู‡ ู…ุนู„ูˆู…ุงุช

887
01:25:52,050 --> 01:25:55,450
ูƒุจูŠุฑุฉ ูˆูƒุซูŠุฑุฉ ูˆู…ู„ูŠุงู† ู…ุนู„ูˆู…ุงุช ูŠุนู†ูŠ ููŠู‡ ูƒุชูŠุฑ ู…ุนู„ูˆู…ุงุช

888
01:25:55,450 --> 01:25:59,890
ู…ู…ูƒู† ุงู„ุฏูƒุชูˆุฑ ู…ุง ุงุชุทุฑู‚ ุฅู„ู‡ุง ูุฅู†ุชูˆุง ู…ุง ุช .. ูŠุนู†ูŠ

889
01:25:59,890 --> 01:26:03,410
ุชุณุฏุฏูˆุด ุนู„ู‰ ุญุงู„ูƒ ูˆ ุชุฑุฌุนูˆุง ุชุณุฃู„ูˆุง ุนู†ู‡ุง ูˆุฎู„ุงุต ูŠุนู†ูŠ

890
01:26:03,410 --> 01:26:06,850
ุทุงู„ู…ุง ุงู„ุฏูƒุชูˆุฑ ู…ุง ุฑูƒุฒ ุนู„ูŠู‡ุง ูุงู„ุชุฑูƒูŠุฒ ุนู„ูŠู‡ุง ู…ุด ู‡ูŠูƒูˆู†

891
01:26:06,850 --> 01:26:11,910
ุจุงู„ู‚ุฏุฑ ุงู„ู„ูŠ ุงู„ุฏูƒุชูˆุฑ ุดุงู‡ูˆ ูŠุนู†ูŠ ุตุญูŠุญ .. ุตุญูŠุญุงู„ู…ุฑุงุฌุน

892
01:26:11,910 --> 01:26:18,310
ุงู„ู„ูŠ ุฒูŠ ู‡ูŠูƒ ุฃู†ุง ุจู‚ูˆู„ ูŠุนู†ูŠุŒ ูŠุนู†ูŠ ุฅุฐุง ุงู„ูˆุงุญุฏ ุนู†ุฏู‡

893
01:26:18,310 --> 01:26:22,830
ุงู‡ุชู…ุงู… ุจู…ุฑุถ ู…ุนูŠู†ุŒ ุจุญุงู„ุฉ ู…ุนูŠู†ุฉุŒ ุจุฏู‡ ูŠูู‡ู… ุฌุงู†ุจ ู…ุนูŠู†ุŒ

894
01:26:22,830 --> 01:26:28,550
ู…ุด ุบู„ุทุŒ ูŠูƒูˆู† ุทุจุนุงู‹ ูŠุนู†ูŠ ููŠ ุนุฒุฏ ุงู„ู€Net ูˆุงู„ุฅู†ุชุฑู†ุช

895
01:26:28,550 --> 01:26:34,330
ูˆุงู„ู€Google ูˆูƒุฐุงุŒ ู…ู…ูƒู† ุงู„ุฃู…ูˆุฑ ุงุฎุชู„ูุชุŒ ุจุณ ุนูŠุจ

896
01:26:34,330 --> 01:26:39,040
ุงู„ู…ุตุงุฏุฑ ุงู„ุชุงู†ูŠุฉ ููŠ ุงู„ู…ุนู„ูˆู…ุงุชุงู„ู„ูŠ ู‡ูŠ ู‚ุถูŠุฉ ุฅู†

897
01:26:39,040 --> 01:26:44,660
ุฃุญูŠุงู†ู‹ุง ู…ุด ู…ูˆุซู‚ุฉ ุงู„ู€ ยซู†ุชยป ูŠู…ูƒู† ุชู‚ุน ููŠ ู…ุตุฏุฑ ูŠุนุชุจุฑ

898
01:26:44,660 --> 01:26:51,640
ุถุนูŠูุŒ ูŠุนุชุจุฑ ุจุงู„ุฃุฎูŠุฑ ุฃูŠ ู…ุนู„ูˆู…ุฉ ู…ู…ูƒู† ุชูƒูˆู† ุนุจุงุฑุฉ ุนู†

899
01:26:51,640 --> 01:26:59,740
ู†ุณู…ูŠู‡ุง ุฑุฃูŠ ุดุฎุต ู…ุนูŠู† ูŠุนู†ูŠุŒ ู…ุด ุนุงุฑู ุนู„ูŠุงุŸ ู…ุด ุจู‚ุตูŠู†

900
01:26:59,740 --> 01:27:08,860
ุญู‚ูŠู‚ุฉ ูุงู„ุขู† ู„ู…ุง ู†ู‚ุฑ ู‡ุฐุง ุงู„ูƒุชุงุจ ู…ุงุดูŠุฃู†ุง ุจุงุนุชุจุฑ ุฅุฐุง

901
01:27:08,860 --> 01:27:13,400
ุงู„ูˆุงุญุฏ ุจุฏูŠ ูŠุฏุฑุณ ุทุจ ูˆูŠูƒูˆู† ุนู†ุฏู‡ ุฎุตูˆุตุง ูŠุนู†ูŠ ุฃู†ุง ู…ู‚ุฏุฑ

902
01:27:13,400 --> 01:27:17,660
ุฃู†ู‡ ุนู†ุฏูƒู… ุงู…ุชุญุงู†ุงุช ุชุงู†ูŠุฉ ูˆู…ูˆุงุฏ ุชุงู†ูŠุฉ ูˆู…ูˆุงุถูŠุน ุชุงู†ูŠุฉ

903
01:27:17,660 --> 01:27:25,610
ู…ุทู„ูˆุจุฉ ู…ู†ูƒู… ุฃู†ู‡ุงู„ูˆุงุญุฏ ุจุฏูŠ ูŠูˆุฎุฏ ุฒูŠ ู…ุง ุชู‚ูˆู„ ูŠุฑูƒุฒ ููŠ

904
01:27:25,610 --> 01:27:31,690
ุฐู‡ู†ู‡ ุนู„ู‰ ุฅู†ู‡ ูŠุณุชูˆุนุจ ุงู„ู…ูุงู‡ูŠู… ูˆูŠุณุชูˆุนุจ ุงู„ู…ูุงู‡ูŠู… ุจู‚ุฏุฑ

905
01:27:31,690 --> 01:27:38,430
ุงู„ู…ุณุชุทุงุน ู…ู† ุฎู„ุงู„ ุฃู…ุซู„ุฉ ุชู‚ุฑู‘ุจ ู„ู‡ ุงู„ูู‡ู… ูˆุชูƒูˆู† ูŠุนู†ูŠ

906
01:27:38,430 --> 01:27:44,450
ููŠู‡ ุฅู„ู‡ุง ูŠุนู†ูŠ ุดูŠุก ู‡ูˆ ุดุงูู‡ ูŠุนู†ูŠ ุฃู†ุง ูˆุงู„ู„ู‡ุŒ ุขู‡ ูˆุงู„ู„ู‡

907
01:27:44,450 --> 01:27:47,960
ุดูˆูุช ุซู„ุงุซูŠู…ูŠุง ุฃูˆ ุดูˆูุช ยซSkills of AnemiaยปุดุงูŠู Down

908
01:27:47,960 --> 01:27:51,760
Syndrome ุดุงูŠู ู†ุงุณ ุนู†ุฏู‡ู… Cancer ุงู„ุฃุดูŠุงุก ุงู„ู„ูŠ ุฃู†ุช

909
01:27:51,760 --> 01:27:56,980
ุจุชุดูˆูู‡ุง ู„ู…ุง ุชูƒูˆู† ุฅุดูŠ ุจุชูƒูˆู† ุจุชุดูˆูู‡ ุฅู†ูƒ ุชูู‡ู… ุจุฏู‚ุฉ

910
01:27:56,980 --> 01:28:01,500
ู„ูŠุด ู‡ุฐุง ุงู„ุฃู…ุฑ ุญุฏุซุŒ ู‡ุฐุง ุถุฑูˆุฑูŠ ุฌุฏุงู‹ ูู„ู…ุง ูŠูƒูˆู† ุญุฏ

911
01:28:01,500 --> 01:28:06,120
ุจูŠุดุฑุญู„ูƒ ุงู„ุชูุตูŠู„ ุฒูŠุงุฏุฉ ูŠุง ุฑูŠุช ูŠูƒูˆู† ุนู†ุฏูŠ ู…ุฑุฌุน ุฃู‚ุฏุฑ

912
01:28:06,120 --> 01:28:12,460
ุฃุฑุฌุนู„ู‡ ุนุดุงู† ุฃู‚ุฑุฃ ุนู† ู‡ุฐู‡ ุงู„ุญุงู„ุฉ ุฃู…ุง ูƒุงู„ุขู† ู…ูุงู‡ูŠู…

913
01:28:12,980 --> 01:28:19,740
ุจุงู„ุฐุงุช ุฅู† ู†ุชูƒู„ู… ุนู† ุงู„ู…ู†ุงุนุŒ ุนู† ุงู„ูˆุฑุงุซุฉุŒ ุงู„ู…ูุงู‡ูŠู…

914
01:28:19,740 --> 01:28:26,460
ูŠุนู†ูŠุŒ ุจุฏู„ ูˆุงุญุฏ ู„ู…ุง ู†ุชูƒู„ู… ุนู„ู‰ ุดูˆ ูŠุนู†ูŠ ุงู„ู€Structure

915
01:28:26,460 --> 01:28:30,980
of the DNAุŒ ููŠู‡ ูƒุฑูˆู…ูˆุฒูˆู…ุŒ ุงู„ู…ู‚ูˆู„ ูƒุฑูˆู…ูˆุฒูˆู… ู…ูˆุฌูˆุฏุŒ

916
01:28:30,980 --> 01:28:35,820
ุณูˆุงุก ูŠุนู†ูŠ ุงู„ุญุจู„ ู‡ุฐุง ู„ูุชู‡ ูˆู„ุง ูุฑุชู‡ุŒ ู…ุง ู‡ูˆ ุญุจู„ุŒ

917
01:28:35,820 --> 01:28:40,740
ุจุงู„ุฃุฎูŠุฑ ุญุจู„ุŒ ู…ุงุดูŠุŸ ููŠ ุญุงู„ุฉ ุงู„ู€Cell DivisionุŒ ุจุฏูŠู‡ุง

918
01:28:40,740 --> 01:28:45,130
ู…ุถุบูˆุท ูƒุชูŠุฑุŒููŠ ุญุงู„ุฉ ุงู„ู„ูŠ ู„ู…ุง ุจุฏูŠ ุฃุดุชุบู„ ุนู„ูŠู‡ุงุŒ ุจุฏูŠ

919
01:28:45,130 --> 01:28:51,730
ุฃููƒู‡ ู„ู…ุง ุฃู†ุง ุฃููƒู‡ุŒ ู…ุฑุงุช ุจููƒู‡ ู†ุตู ููƒุฉ ุนุดุงู† ูŠุนู†ูŠ

920
01:28:51,730 --> 01:28:56,890
ุจูƒูˆู† ููŠู‡ุง ู…ุฌุงู„ ูˆู‚ุชู‡ุง ุฅู†ู‡ ููŠู‡ promoter regions ููŠ

921
01:28:56,890 --> 01:29:00,870
ุจุนุถ ุงู„ู€ยซุจุฑูˆู…ูˆุชุฑ ุฑูŠุฌู†ยป ู‚ุจู„ ุงู„ุฌูŠู† ุชู…ุงู…ุงู‹ ูˆููŠู‡

922
01:29:00,870 --> 01:29:05,290
promoter regions ู…ู…ูƒู† ุชูƒูˆู† ุจุนูŠุฏ ุนู†ู‡ ุจู…ุง ููŠู‡ุง ุจุนูŠุฏ

923
01:29:05,290 --> 01:29:09,870
ุนู†ู‡ ุญุชู‰ ู„ูˆ ุนู„ู‰ ูƒุฑู…ูˆุฒูˆู… ุซุงู†ูŠ ุจุณ ู„ุฃู†ู‡ ูƒู„ ูˆุงุญุฏ ุฅู„ู‡

924
01:29:09,870 --> 01:29:15,930
ู…ูƒุงู†ู‡ู…ุงุดูŠ ู‡ูŠูƒ ุจุงุญุชูุธ ููŠู‡ ุงู„ุฃู…ูˆุฑ ุจุงู„ู†ุณุจุฉ ู„ู„ุฅุณู„ุงูƒ

925
01:29:15,930 --> 01:29:19,850
ู‡ุฐู‡ ูˆุงู„ุฅุญุจุงู„ ู‡ุฐู‡ ู…ุงุดูŠ ุญุงุฌุฉ ุจุชู‚ุฏุฑ ุงู„ูˆุธูŠู ุงู„ู…ุทู„ูˆุจ

926
01:29:19,850 --> 01:29:25,030
ูŠุนู†ูŠ ุฎู„ูŠู‡ุง ุจุดูƒู„ ู…ุจุณุท ูˆู„ู…ู‘ุง ุฃู†ุชูˆุง ุชู‚ุฑุฃูˆุง ู…ู† ุงู„ูƒุชุงุจ

927
01:29:25,030 --> 01:29:32,570
ุชุทู„ุนูˆุง ุงู„ุตูˆุฑ ุงู‚ุฑุฃูˆุง ุงู„ุฌุฏุงูˆู„ ุงู‚ุฑุฃูˆุง ุงู„ู…ุฑุจุนุงุช

928
01:29:32,570 --> 01:29:36,550
ู‡ูŠูƒ ุงู„ู„ูŠ ุญุงุทุท ููŠู‡ุง ุฅุดูŠ ุงู‚ุฑุฃูˆุง ุงู„ู…ู‚ุฏู…ุฉ ูˆุงู‚ุฑุฃูˆุง

929
01:29:36,550 --> 01:29:44,010
ุงู„ุฎุชุงู…ูŠุนู†ูŠ ุฏุงูŠู…ุงู‹ ุฅุฐุง ุจูŠุญุทู„ูƒ ุฅุดูŠ ู‡ูˆ ุจูŠูƒูˆู† ุจุฏูŠูƒ

930
01:29:44,010 --> 01:29:48,230
ุชูู‡ู… ู…ู‚ู‡ูˆู… ู…ุนูŠู†ุŒ ู‡ุฐุง ุงู„ู„ูŠ ุจูŠู‡ู…ู†ุงู‡ุŒ ู…ุงุดูŠุŸ ุงู„ู€Too

931
01:29:48,230 --> 01:29:54,150
much details ู…ุด ู…ุทู„ูˆุจุฉุŒ ู…ุงุดูŠุŸ ูˆู…ุด ุดุทุงุฑุฉ ูŠุนู†ูŠุŒ ูˆู…ุด

932
01:29:54,150 --> 01:30:02,350
ุจุงู„ุฐุงุช ุฅุฐุง ุดุบู„ ูŠุนู†ูŠ ูŠู…ูƒู† ู…ุด ู…ุชูู‚ ุนู„ูŠู‡ุงุŒ ู…ุงุดูŠุŸุทุจุนุง

933
01:30:02,350 --> 01:30:05,170
ู†ุณุชุบู„ ูˆุฌูˆุฏูƒ ูŠุง ุฏูƒุชูˆุฑ ุจุฑุถู‡ ููŠ ู†ู‚ุทุฉ ุชุงู†ูŠุฉ ูŠุนู†ูŠ ุฃู†ู‡

934
01:30:05,170 --> 01:30:09,790
ุงู„ู€ ยซุฌุฏูˆู„ยป ุงู„ู„ูŠ ุจุนุชู†ุงู„ู‡ ู„ู„ุทู„ุงุจ ุตุญูŠุญ ุฅู†ู‡ ููŠู‡ ูŠุนู†ูŠ

935
01:30:09,790 --> 01:30:12,670
ู‡ุฐุง ุงู„ูƒู„ุงู… ุจูˆุฌู‡ู‡ ู„ู„ุทู„ุงุจ ูŠุนู†ูŠ ุตุญูŠุญ ุฅู†ู‡ ููŠู‡ 18

936
01:30:12,670 --> 01:30:16,490
chapter ู…ูˆุฌูˆุฏูŠู† ู„ูƒู† ุทุจูŠุนูŠ ู…ุด ู‡ูŠูุชู… ุดุฑุญ ุงู„ู€18

937
01:30:16,490 --> 01:30:19,810
chapter ุจุงู„ุชูุตูŠู„ ูŠุนู†ูŠ ุงู„ุฏูƒุชูˆุฑ ูˆุตู„ู„ูŠ ุตูˆุฑุฉ ูˆูŠุนู†ูŠ

938
01:30:19,810 --> 01:30:24,650
ุฃุชู…ู†ู‰ ุฃู† ุฃุคูƒุฏู‡ุง ูƒู…ุงู† ุฃุฌูŠุชู‡ุงุฅู† ุงู„ุดุจุงุชุฑ ุงู„ุฃุฎูŠุฑุฉ ู„ู†

939
01:30:24,650 --> 01:30:27,770
ุชุชู… ุชุฃุฎุฐ ุงู„ุฃู…ุฑุงุถ ููŠู‡ุง ุจุงู„ุชูุงุตูŠู„ุŒ ู„ุฃู† ู‡ุฐู‡ ูƒู„ู‡ุง

940
01:30:27,770 --> 01:30:31,530
ุฃู…ุฑุงุถ ุณุฑูŠุฑูŠุฉ ุงู„ุชูุงุตูŠู„

941
01:30:31,530 --> 01:30:36,970
ุงู„ุณุฑูŠุฑูŠุฉ ุทุจุนุง ู…ุง ู‡ุฐู‡ ูƒู„ ุญูŠุงุชูƒ ุจุฏูƒ ุชุชุนู„ู… ุนู„ูŠู‡ุงุŒ ูˆู‡ูŠ

942
01:30:36,970 --> 01:30:41,750
ู„ู…ุฑุญู„ุฉ ู„ุงุญู‚ุฉ ุจุงู„ุธุจุท ุงู„ุฃู…ุฑุงุถ ุงู„ุณุฑูŠุฑูŠุฉ ู…ุง ุจุฏู†ุง ู†ุฏุฎู„

943
01:30:41,750 --> 01:30:45,880
ุชูุงุตูŠู„ู‡ุงูŠุนู†ูŠ ุฃู† ุชู…ู†ุชุงุดุฑ ุดุงุจุชุฑ ุตุญูŠุญ ุนุฏุฏ ู„ูƒู† ููŠ

944
01:30:45,880 --> 01:30:48,820
ุงู„ู…ุถู…ูˆู† ู‡ูŠูƒูˆู† ุนู„ู‰ ุนุฏุฏ ุงู„ุฃุณุงุจูŠุน ุงู„ู„ูŠ ู…ูˆุฌูˆุฏุฉ ุงู„ู„ูŠ ู‡ูŠ

945
01:30:48,820 --> 01:30:53,140
14 ุฃูˆ 13 ุฃุณุจูˆุน ุจุงู„ุธุจุท ูŠุนู†ูŠ ู…ุด ู‡ู†ุฃุฎุฏ ุชู…ู†ุชุงุดุฑ ุดุงุจุชุฑ

946
01:30:53,140 --> 01:30:59,240
ุจุงู„ุชูุตูŠู„ ูŠุนู†ูŠ ุงู„ู…ูู‡ูˆู… ุจุชุฑุณุฎ ู…ู† ุฎู„ุงู„ ุงู„ู…ุซุงู„ ุตุญูŠุญ

947
01:30:59,240 --> 01:31:04,820
ู…ุซุงู„ ุฅุฐุง ุฃู†ุช ูุงู‡ู… ูƒู…ุฑุถุฅู†ู‡ ููŠ ุญุงู„ุฉ ุงุณู…ู‡ุง ูƒุฏุงุŒ ุจูŠุฌูŠ

948
01:31:04,820 --> 01:31:08,460
ุงู„ู…ุฑูŠุถ ุนู†ุฏู‡ ู‡ูŠูƒ ู„ุงุญุธู†ุง ุนู„ูŠู‡ ู‡ูŠูƒุŒ ู„ูŠุด ุจูŠูƒูˆู† ู‡ูŠูƒ

949
01:31:08,460 --> 01:31:13,520
ูุฅู†ุช ู‡ู†ุง ุจุชุณูŠุจ ูŠุนู†ูŠ ู…ู…ูƒู† ุญุชู‰ ุทุจุนุงู‹ ูŠู…ูƒู† ุงู„ุขู† ุนู„ู‰

950
01:31:13,520 --> 01:31:19,660
ู…ุณุชูˆู‰ ุทุงู„ุจ ุทุจ ุซุงู†ูŠ ุซุงู†ูŠ ุซุงู„ุซ ุจุฏุงูŠุชู‡ ูŠู…ูƒู† ูŠุนู†ูŠ

951
01:31:19,660 --> 01:31:24,360
ู…ุนู„ูˆู…ุงุช ูƒุชูŠุฑ ูˆุชูุงุตูŠู„ ูƒุชูŠุฑุฉ ุจุณ ุฅุญู†ุง ุจู†ุงุฎุฐู‡ุง ุฃู†ุง

952
01:31:24,360 --> 01:31:30,430
ุจู‡ู…ู†ูŠ ุงู„ุฃู…ุซู„ุฉ ุงู„ู„ูŠ ุจุชูˆุถุญ ุงู„ู…ูู‡ูˆู…ูุงู‡ู… ุนู„ูŠูƒ ูƒูŠูุŸ

953
01:31:30,430 --> 01:31:34,230
ูŠุนู†ูŠ ู„ู…ุง ุชู‚ูˆู„ู‘ูŠ ยซA.B.O Systemยป ูƒู„ูƒู… ุจุชุนุฑููˆุง ูƒูŠู

954
01:31:34,230 --> 01:31:37,330
ุงู„ู€Genetics ุชุจุนุชู‡ ูˆู…ูŠู† ุงู„ู€Dominant ูˆู…ูŠู†

955
01:31:37,330 --> 01:31:40,670
ุงู„ู€Recessive

956
01:31:40,670 --> 01:31:45,050
ูˆูƒูŠู ุจูƒูˆู† ูˆูƒูŠู ูƒุฐุง ูˆูƒูŠู ูƒุฐุง ููŠุนู†ูŠ ู‡ุฐู‡ ุงู„ุฃุดูŠุงุก ุฃู†ุง

957
01:31:45,050 --> 01:31:50,190
ุจู‡ู…ู† ุงู„ู…ูุงู‡ูŠู… ูˆุงู„ู…ูุงู‡ูŠู… ูŠุชู… ุดุฑุญู‡ุง ููŠ ุดูƒู„ ู…ุจุณุท ู…ู†

958
01:31:50,190 --> 01:31:55,450
ุฎู„ุงู„ ุฃู…ุซู„ุฉ ูุฅุฐุง ููŠ ู…ุซุงู„ ูŠุนู†ูŠ ุจุงู„ุฐุงุช ุจูŠุจูŠู† ู…ูู‡ูˆู…

959
01:31:55,450 --> 01:32:01,560
ู…ุนูŠู†ูƒูˆูŠุณ ูˆุงู„ูˆุงุญุฏ ู‡ูŠูƒ ูŠุงุฎุฏู‡ ุจุดูƒู„ ู…ุจุณุท ู†ุนุด ู†ุงุฎุฏ

960
01:32:01,560 --> 01:32:06,840
ุจุงู„ุชูุงุตูŠู„ ุงู„ุฏู‚ูŠู‚ุฉ ูˆุฅู† ูƒุงู† ูŠุนู†ูŠ ุฅุฐุง ุงู„ูˆุงุญุฏ ูŠุนู†ูŠ ู‡ุณุง

961
01:32:06,840 --> 01:32:11,480
ุณู…ุน ุงู„ู€ ูŠุนู†ูŠ ู‡ุณุง ุงู„ู€ band ุงู„ู„ูŠ ูู„ุงู†ูŠ ููŠ ุงู„ู€

962
01:32:11,480 --> 01:32:14,700
chromosome ุงู„ู„ูŠ ูู„ุงู†ูŠ ุฃู†ุช ุจุชุชุฎูŠู„ ูˆูŠู† ู‡ูŠุŒ ุดูˆ ู‡ูŠุŒ

963
01:32:14,700 --> 01:32:19,820
ู…ุงุดูŠ ูˆู„ู…ู‘ุง ู†ุชู„ุงู‚ู‰ ุงู„ segment ููŠู‡ุง ูƒุฏู‡ ู…ู† gene ูƒูŠู

964
01:32:19,820 --> 01:32:24,460
ุชุฑุชูŠุจู‡ุง ูˆูƒู… intron ูˆูƒู… exon ูˆูƒุฏู‡ ูŠุนู†ูŠ ู„ู…ุง ุฃู†ุง ุฃู‚ูˆู„

965
01:32:24,460 --> 01:32:28,670
ูˆุงู„ู„ู‡ ุงู„ู€FFMุŒ FMFุงู„ุฌูŠู† ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€ Pyrene ุงู„ู€

966
01:32:28,670 --> 01:32:34,250
ยซุฅุฌุฒูˆู†ยป ุฑู‚ู… 2 ูˆุฑู‚ู… 10 ู‡ู… ุงู„ู„ูŠ ููŠู‡ู… ุจู„ูŠู…ุงุฑูุฒู… ุงู„ู„ูŠ

967
01:32:34,250 --> 01:32:38,690
ู‡ูŠ ุญูˆุงู„ูŠ 200 ู†ูˆุน ุจู„ูŠู…ุงุฑูุฒู… ูˆุฅุฐุง ูƒุงู† double ูŠุนู†ูŠ

968
01:32:38,690 --> 01:32:42,950
double heterozygous ุฃูˆ homozygous ู‡ูŠ ุงู„ู„ูŠ ุจุชูƒูˆู†

969
01:32:42,950 --> 01:32:48,930
ุดุฏูŠุฏุฉ ูˆูƒุฐุง ูˆูƒุฐุง ูŠุนู†ูŠ ุจุชุนุทูŠูƒ ุชุตูˆุฑ ุจุณุงุนุฏูƒ ููŠ ูู‡ู…

970
01:32:48,930 --> 01:32:53,230
ุงู„ู…ุฑุถ ุจุณุงุนุฏูƒ ููŠ ู‚ุฑุงุกุฉ ุงู„ู…ุนู„ูˆู…ุงุช ุฅุฐุง ู‚ุฑูŠุชู‡ุง ู…ู† ู…ุฌู„ุฉ

971
01:32:53,230 --> 01:33:01,560
ุฃูˆ ู…ู† ู…ุญู„ุทุจุนู‹ุง ุฅู† ุดุงุก ุงู„ู„ู‡ ุฅู† ุดุงุก ุงู„ู„ู‡ ุฎูŠุฑ ุฃู†ุง ุฅู†

972
01:33:01,560 --> 01:33:07,000
ุดุงุก ุงู„ู„ู‡ ูŠุนู†ูŠ ุงู„ูŠูˆู… ุงู„ู€ chapter ุงู„ุชุงู„ุช ุฌุงูŠ ู…ุด ุทูˆูŠู„

973
01:33:07,000 --> 01:33:13,700
ูƒุชูŠุฑ ูู„ูŠู†ุง ุฅุฐุง ููŠ ุญุฏ ุนู†ุฏู‡ ุฃุณุฆู„ุฉ ููŠ group ุงู„ู€

974
01:33:13,700 --> 01:33:19,910
WhatsAppุจุฑุถู‡ ุจูŠุญุท ุงู„ูˆุงุญุฏ ุฅุฐุง ุจุฏู‡ ุฃุณุฆู„ุฉ ุงุณุฃู„ู‡ ุฃู†ุง

975
01:33:19,910 --> 01:33:24,090
ู…ุจุณูˆุท ุงู„ูŠูˆู… ุฅู†ู‡ ุฅุฐุง ููŠ ุฃุณุฆู„ุฉ ูˆุญุชู‰ ู†ุดุฑุญ ุจุจุทุก ู…ุด

976
01:33:24,090 --> 01:33:28,690
ุญุฑูŠุต ุนู„ู‰ ุฅู†ู‡ ุฃุฎู„ุต ูƒู„ ุดูŠุก ูŠุนู†ูŠ ูŠู…ูƒู† ููŠ ูุตูˆู„ ู†ู‚ุฏุฑ

977
01:33:28,690 --> 01:33:34,250
ู†ุดูŠุฑ ุฅู„ูŠู‡ุง ุฅุดุงุฑุฉ ุจุณูŠุทุฉ ุนุงุฏุฑุฉ ุจู‚ุฏุฑ ู…ุง ุฅู†ู‡ ููŠ ุฃุดูŠุงุก

978
01:33:34,250 --> 01:33:39,970
ู…ูุงู‡ูŠู… ุฃู‡ู… ูŠุนู†ูŠูˆ ุจู…ู…ูƒู†ูƒูˆุง ุชุฌู…ุนูˆุง ุงู„ุฃุณุฆู„ุฉ ุณูˆุงุก ูŠุนู†ูŠ

979
01:33:39,970 --> 01:33:43,250
ุฎู„ุงู„ ุงู„ู…ุญุงุถุฑุงุช ุฃูˆ ููŠ ุจุฏุงูŠุฉ ุฃูŠ ู…ุญุงุถุฑุฉุŒ ูŠุนู†ูŠ ุงู„ุฏูƒุชูˆุฑ

980
01:33:43,250 --> 01:33:46,650
ุจูŠุชุฑูƒ ูุฑุตุฉ ู„ูƒูˆุง ุชุณุฃู„ูˆุง ุณูˆุงุก ุจุงู„ุตูˆุชุŒ ุณูˆุงุก ุจุงู„ู†ุต

981
01:33:46,650 --> 01:33:50,590
ูƒุชุงุจุฉุŒ ุฒูŠ ู…ุง ุจุชุญุจูˆุง ุจุชุณุฃู„ูˆุง ููŠ ุจุฏุงูŠุฉ ูƒู„ ู…ุญุงุถุฑุฉ ุฃูˆ

982
01:33:50,590 --> 01:33:54,370
ููŠ ู†ุต ุงู„ู…ุญุงุถุฑุฉุŒ ูŠุนู†ูŠ ุงู„ุฃู…ุฑ ู…ุชุฑูˆูƒ ู„ูƒูˆุง ุจูƒู„ ุงู„ุญุฑูŠุฉ

983
01:33:54,370 --> 01:33:57,970
ุฅู† ุดุงุก ุงู„ู„ู‡ ุงู„ู„ู‡ ูŠุนุทูŠูƒู… ุงู„ุนุงููŠุฉุŒ ูˆ ุงู„ู„ู‡ ูŠุฑุถู‰

984
01:33:57,970 --> 01:34:01,780
ุนู„ูŠูƒู…ุŒ ูˆ ู†ุดูˆููƒู… ุนู„ู‰ ุฎูŠุฑ ุจุนุฏ ุฏูƒุฑุฉุณุงู…ุญู†ุง ุนู„ู‰ ุงู„ุบู„ุจ

985
01:34:01,780 --> 01:34:03,580
ูŠุง ุฏูƒุชูˆุฑุŒ ูŠุนุทูŠู†ุง ุงู„ูุนุงู„ูŠุฉ ู„ุงุŒ ู„ุงุŒ ู„ูŠุณ ุบู„ุจุŒ ุฃู†ุง

986
01:34:03,580 --> 01:34:09,760
ูˆุงู„ู„ู‡ ุฃุชุดุฑู ุฃู†ูŠ ุฃุดุชุฑูƒ ู…ุนุงูƒู…ุŒ ูˆ ุงู„ู„ู‡ ูŠูˆูู‚ูƒู…ุŒ ูŠุนุทูŠู†ุง

987
01:34:09,760 --> 01:34:11,880
ุงู„ูุนุงู„ูŠุฉ ูˆุฅุญู†ุง ูˆุงู„ู„ู‡ ุฃูƒุซุฑ ุฒุงุฏู†ุง ุงู„ุดุฑู ูŠุง ุฏูƒุชูˆุฑุŒ

988
01:34:11,880 --> 01:34:15,160
ูˆุงู„ู„ู‡ ูŠูƒููŠ ุงู„ู„ู‡ ูŠุญูŠุทุŒ ุงู„ู„ู‡ ูŠุญูŠุทุŒ ูŠู„ุง ุงู„ุณู„ุงู… ุนู„ูŠูƒู…

989
01:34:15,160 --> 01:34:15,960
ููŠ ุฑุนุงูŠุฉ ุงู„ู„ู‡