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ุจุณู… ุงู„ู„ู‡ ุงู„ุฑุญู…ู† ุงู„ุฑุญูŠู… ู†ุณุชูƒู…ู„ ุทู„ุงุจู†ุง ูˆุทุงู„ุจุงุชู†ุง
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ุงู„ุนุฒุงุก ููŠ ุงู„ู…ูˆุถูˆุน ุงู„ุซุงู„ุซ ู…ุนู†ุงู‡ ููŠ ู…ุงุฏุฉ ุทุจ ุงู„ุชุฃู‡ูŠู„
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ูˆู‡ูˆ ู…ุงุฏุฉ ุงู„ุฌู„ุทุงุช ุงู„ุฏู…ุงุบูŠุฉ ุงู„ู€ management ูˆุงู„ู€
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rehabilitation ุทุจุนุง ุงู„ู€ stroke ุฅู„ู‡ุง ุฃูƒุซุฑ ู…ู† ู…ุณู…ู‰
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ูŠุนู†ูŠ ููŠ ู†ุงุณ ุจูŠุทู„ู‚ ุนู„ูŠู‡ุง brain attack ูˆู„ูƒู† ุงุณู…ู‡ุง
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ุงู„ุนู„ู…ูŠ ู‡ูˆ cerebrovascular accident ุฃูˆ ุงู„ู€ CVA
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ุงู„ู€ stroke ู‡ูŠ acute loss of circulation ูŠุนู†ูŠ blood
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circulation to a certain area in the brain with
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resultant ischemia and loss of neuronal function
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ูŠุนู†ูŠ ู‡ูŠ ูู‚ุฏุงู† ู„ู„ุชุฑูˆูŠุฉ ุงู„ุฏู…ูˆูŠุฉ ููŠ ู…ู†ุทู‚ุฉ ู…ุนูŠู†ุฉ ู†ุชุฌ ุนู†ู‡ุง
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ุฎู„ู„ ููŠ ุงู„ูˆุธูŠูุฉ ุงู„ุนุตุจูŠุฉ ู„ู„ุฎู„ุงูŠุง ุงู„ู…ูˆุฌูˆุฏุฉ ููŠ ุงู„ุฏู…ุงุบ
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it occurs when an artery that carries oxygen
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nutrients to the brain is either blocked or burst ุงู†ุณุฏ
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ุฃูˆ ุงู†ูุฌุฑ ู‡ุฐู‡ ุงู„ู…ู†ุทู‚ุฉ cannot get the needed oxygen
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and the needed nutrients ูˆุจุฑุถู‡ it cannot clear out
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the waste products that it has ูˆู„ู‡ุฐุง ุงู„ุณุจุจ ู‡ุฐู‡
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ุงู„ู…ู†ุทู‚ุฉ ุจุชุจุฏุฃ ุชู…ูˆุช ุจุนุฏ ูƒุฏู‡ ูˆู„ูƒู† ู…ุน ุงู„ุชู‚ุฏู… ุงู„ุนู„ู…ูŠ
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ุจุฏุฃุช ุชุฃุซูŠุฑุงุช ุงู„ุฌู„ุทุฉ ุนู„ู‰ ุงู„ุฏู…ุงุบ ูŠุนู†ูŠ ู†ูˆุนู‹ุง ู…ุง ุชุฎู
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ุจุงุณุชุฎุฏุงู… ุจุนุถ ุงู„ุชุฏุงุฎู„ุงุช ุงู„ุนู„ุงุฌูŠุฉ ุงู„ุทุงุฑุฆุฉ ุฃูˆ ุจุนุถ
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ุงู„ุชุฏุงุฎู„ุงุช ุงู„ูˆู‚ุงุฆูŠุฉ ูˆู„ู‡ุฐุง ุงู„ุณุจุจ ูƒู„ ู…ุง ู†ุชุนุงู…ู„ ุฃุณุฑุน
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ูƒู„ ู…ุง ุจู†ู‚ุฏุฑ ู†ู†ู‚ุฐ ุนุฏุฏ ู…ู† ุงู„ุฎู„ุงูŠุง ุฃูƒุซุฑ ูˆู„ู‡ุฐุง ุงู„ุณุจุจ
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ูŠุทู„ู‚ ู…ุตุทู„ุญ time is brain Okay ุงู„ู€ stroke ู‡ูˆ the most
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serious neurological disorder ููŠ ุฃู…ุฑูŠูƒุง ูˆููŠ ู…ุนุธู…
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ุงู„ุฏูˆู„ ุงู„ุนุงู„ู… ุงู„ู…ุชุญุถุฑ ุฃูˆ ุงู„ุนุงู„ู… ุงู„ุบู†ูŠ ุจูŠุดูƒู„ ููŠ
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ุฃู…ุฑูŠูƒุง ุฃูƒุซุฑ ู…ู† ุฎู…ุณูŠู† ููŠ ุงู„ู…ุฆุฉ ู…ู† ูƒู„ ุญุงู„ุงุช ุงู„ุฏุฎูˆู„
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ุงู„ู„ูŠ ุจุณุจุจ ุฃู…ุฑุงุถ ุงู„ุนุตุจ ุณู†ูˆูŠู‹ุง ุฃูƒุซุฑ ู…ู† ุณุจุนู…ุงุฆุฉ ุฃู„ู
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ุฃู…ุฑูŠูƒูŠ ูŠุตุงุจูˆุง ุจุฌู„ุทุฉุŒ ู…ู†ู‡ู… ุฎู…ุณู…ุงุฆุฉ ุฃู„ู ู„ู„ู…ุฑุฉ
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ุงู„ุฃูˆู„ู‰ุŒ ูˆู‡ุฐุง ุนุฏุฏ ู…ู‡ูˆู„ ุฌุฏุงุŒ ูŠุนู†ูŠ ุชู‚ุฑูŠุจุง ุนุฏุฏ
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ุงู„ุฌู„ุทุงุช ุจุนุฏุฏ ุชู‚ุฑูŠุจุง ุญุงู„ุงุช ุงู„ูˆููŠุงุช ู…ู† ุงู„ู€ COVID-19
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ุญุงู„ูŠู‹ุงุŒ ูˆ 200 ุฃู„ู ู‡ูˆ recurrent stroke ูƒู„ ุฎู…ุณุฉ
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ูˆุฃุฑุจุนูŠู† ุซุงู†ูŠุฉ ุฃู…ุฑูŠูƒูŠ ุจูŠุตุงุจ ุจุฌู„ุทุฉ ูˆูƒู„ ุณุชุฉ ูˆุฎู…ุณูŠู†
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ุซุงู†ูŠุฉ ุฃู…ุฑูŠูƒูŠ ุจูŠู…ูˆุช ู…ู† ุฌู„ุทุฉ ูุงู„ุนุฏุฏ ู…ู‡ูˆู„ ูˆุงู„ูˆููŠุงุช
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ู…ู‡ูˆู„ุฉ ู‚ุฏ ุชูƒูˆู† ุจุฃุนุฏุงุฏ ุฃูƒุซุฑ ู…ู† ุนุฏุฏ ุงู„ู„ูŠ ู…ุงุชูˆุง ุจุงู„
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COVID-19 ุจุนุฏุฏ ู…ุฑุงุช ูุนู„ูŠู‹ุง ุจูŠู…ูˆุช ุฃูƒุซุฑ ู…ู† ู…ุฆุฉ ูˆุซู„ุงุซุฉ
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ูˆุณุชูŠู† ุฃู„ู ุฃู…ุฑูŠูƒูŠ ุฃูˆ ู…ุฆุฉ ูˆุณุชูŠู† ุฃู„ู ููŠ ุนุงู… 2001
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ู„ูˆุญุฏู‡ ุงู„ุนุฏุฏ ูˆุตู„ ุชู‚ุฑูŠุจุง ู…ุฆุฉ ูˆุฃุฑุจุนุฉ ูˆุณุชูŠู† ุฃู„ู
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ุจุฑูŠุทุงู†ูŠุง ุงู„ุนุฏุฏ ุชู‚ุฑูŠุจุง ุฃู‚ู„ ุจุณุจุจ ู‚ู„ุฉ ุนุฏุฏ ุงู„ุณูƒุงู†
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ุนุงู…ูŠู‹ุง ูŠุนุชุจุฑ ู‡ูˆ ุงู„ู€ third killer ุจุนุฏ ุฃู…ุฑุงุถ ุงู„ู‚ู„ุจ
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ุงู„ู„ูŠ ู‡ูŠ ุจุชู‚ุชู„ ุชู‚ุฑูŠุจุง ููŠ ุงู„ุนุงู„ู… ุณุจุนุฉ ุนุดุฑ ู…ู„ูŠูˆู† ูˆ all
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forms of cancer ุงู„ู„ูŠ ุจุชู‚ุชู„ ููŠ ุงู„ุนุงู„ู… ููˆู‚ ุงู„ุนุดุฑุฉ
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ู…ู„ูŠูˆู† ุชุณุนุฉ ู…ู† ูƒู„ ุนุดุฑุฉ ู…ุฑุถู‰ ูŠุตุงุจูˆุง ุจุงู„ุฌู„ุทุงุช ุนู…ุฑู‡ ููˆู‚
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ุงู„ุฎู…ุณุฉ ูˆุงู„ุฎู…ุณูŠู† ูˆู„ูƒู† ู‡ุฏูˆู„ ุงู„ู„ูŠ ุจูŠุตูŠุฑ ู…ุนุงู‡ู… ุงู„ุฌู„ุทุฉ
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ุงู„ุฃูˆู„ู‰ ุจุชู„ุชู… ุจุชุญุณู† ูˆุจุชู„ุชู… ุจูŠุตูŠุฑ ููŠ ุนู†ุฏู‡ moderate
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to severe disability ูˆุงู„ุชู„ุช ุงู„ุขุฎุฑ ุจูŠู…ูˆุช ููŠ ุฎู„ุงู„
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ุงู„ุณู†ุฉ ุงู„ู‚ุงุฏู…ุฉ ูˆู„ูƒู† ุงู„ุฏุฑุงุณุงุช ุฃุธู‡ุฑุช ุฃู†ู‡ ููŠ ุฎู„ุงู„
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ุนุดุฑ ุณู†ูˆุงุช 65% ู…ู† ูƒู„ ุงู„ู†ุงุณ ุงู„ู„ูŠ ุนุฏูˆุง ุงู„ุฌู„ุทุฉ ุงู„ุฃูˆู„ู‰
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ุจูŠูƒูˆู†ูˆุง ุชูˆูุฑ
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ุฃู…ุง ู…ู† ู†ุงุญูŠุฉ ุงู„ู€ gender ูู€ ุงู„ู€ stroke ุจุชุคุฏูŠ ุฅู„ู‰
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ุฅุตุงุจุงุช ุฃูƒุซุฑ ุจูŠู† ุงู„ุฑุฌุงู„ ุนู†ู‡ุง ุจูŠู† ุงู„ู†ุณุงุก ูˆู„ูƒู† ุงู„ุณุชุงุช
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ุงู„ู„ูŠ ูŠุตุงุจูˆุง ุจุงู„ุฌู„ุทุงุช ุจูŠู…ูˆุชูˆุง ุฃูƒุซุฑ ู…ู† ู†ุณุจุฉ ุงู„ุฑุฌุงู„
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ุงู„ู„ูŠ ูŠุตุงุจูˆุง ุจุงู„ุฌู„ุทุงุช Okay ุงู„ู€ Hispanic population
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ูŠุนู†ูŠ ุงู„ุณูƒุงู† ุงู„ู„ูŠ ู…ู† ู…ู† ุงู„ุฃุตูˆู„ ุบูŠุฑ ุฃู…ุฑูŠูƒูŠุฉ ุบูŠุฑ
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ุจูŠุถุงุก ุฌุงูŠูŠู† ู…ู† ุฅุณุจุงู†ูŠุง ู…ู† ุงู„ู„ุงุชูŠู†ูˆุฒ ู…ู† ุงู„ุจุฑุงุฒูŠู„
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ูŠุนู†ูŠ ุงู„ู€ Hispanics has lower incidence of CVA and
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you know ูˆู„ูƒู† greater incidence of lacunar
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infarcts ุงู„ู€ sex distribution ูƒู…ุง ุฐูƒุฑู†ุง ุฃู† ุงู„ู€ male
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to female ุซู„ุงุซุฉ ู„ุงุซู†ูŠู† ุญุงู„ูŠู‹ุง ูŠุนู†ูŠ ููŠ ุนู†ุฏู†ุง ุฃูƒุซุฑ ู…ู†
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ุฎู…ุณุฉ ู…ู„ูŠูˆู† ุดุฎุต ู…ุนุงู‡ู… stroke ูˆู…ุงุฒุงู„ูˆุง ุนุงูŠุดูŠู† ู„ุญุชู‰
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ุงู„ุฌู„ุทุงุช
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ู‡ูŠ ุงู„ู€ leading cause of disability ูŠุนู†ูŠ ู‡ูŠ ู…ู†
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ุงู„ู…ุณุจุจุงุช ุงู„ุฃุณุงุณูŠุฉ ู„ู„ุฅุนุงู‚ุงุช ููŠ ุงู„ุนุงู„ู… ุฎู…ุณูŠู† ููŠ
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ุงู„ู…ุฆุฉ ู…ู† ูƒู„ ุงู„ู„ูŠ ุจูŠุตุงุจูˆุง ุจุงู„ุฌู„ุทุงุช ุนู†ุฏู‡ู… one-sided
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00:04:43,480 --> 00:04:46,520
paralysis ุฎู…ุณุฉ ูˆุซู„ุงุซูŠู† ููŠ ุงู„ู…ุฆุฉ ุนู†ุฏู‡ู… depressive
64
00:04:46,520 --> 00:04:50,940
symptoms ุซู„ุงุซูŠู† ููŠ ุงู„ู…ุฆุฉ ู„ุง ูŠุณุชุทูŠุนูˆุง ุงู„ู…ุดูŠ ุจุฏูˆู†
65
00:04:50,940 --> 00:04:55,900
ู…ุณุงุนุฏุฉ ุฎุงุฑุฌูŠุฉุŒ ุณุชุฉ ุนุดุฑูŠู† ููŠ ุงู„ู…ุฆุฉ ู…ุง ุฒุงู„ูˆุง ู…ุนุชู…ุฏูŠู†
66
00:04:55,900 --> 00:04:58,820
ุจุฃุฏุงุก ุฃู†ุดุทุฉ ุงู„ุญูŠุงุฉ ุงู„ูŠูˆู…ูŠุฉ ุนู„ู‰ ุงู„ุขุฎุฑูŠู† ู…ุซู„ ุงู„ู€
67
00:04:58,820 --> 00:05:02,360
groomingุŒ ุงู„ู‡ู†ุฏู…ุฉ ูˆุงู„ุฃูƒู„ ูˆุงู„ุดุฑุจ ูˆุงู„ุญู…ุงู… ูˆ
68
00:05:02,360 --> 00:05:06,540
ุงู„ุฃุฎุฑูˆู† ุนุดุฑูŠู† ููŠ ุงู„ู…ุฆุฉ ุจูŠุนุงู†ูˆุง ู…ู† ูู‚ุฏุงู† ุงู„ู‚ุฏุฑุฉ ุนู„ู‰
69
00:05:06,540 --> 00:05:12,920
ุงู„ุชูˆุงุตู„ ุงู„ู„ุบูˆูŠ ุณูˆุงุก ูƒุงู† ุจุงู„ุงุณุชู‚ุจุงู„ ุฃูˆ ุจุงู„ุชุนุจูŠุฑ ูู‚ุท
70
00:05:12,920 --> 00:05:17,680
ููŠ ุนุงู… 2004 ู‚ุฏุฑูˆุง ุงู„ุนู„ู…ุงุก ุจุชุฑุงุนูŠุฉ ุงู„ู€ stroke
71
00:05:17,680 --> 00:05:23,220
ูˆุงู„ุชุฃู‡ูŠู„ ุจุฃูƒุซุฑ ู…ู† ุชู‚ุฑูŠุจุง 54 ู…ู„ูŠุงุฑ ุฏูˆู„ุงุฑ ุฃู…ุฑูŠูƒูŠ
72
00:05:23,220 --> 00:05:30,040
ุทุจุนุง ู‡ุฐุง ุงู„ุฑู‚ู… ู…ู‡ูˆู„ ู‡ุฐุง ุงู„ุฑู‚ู… ูŠุนู†ูŠ ุจูŠุฏู…ุฑ ุจุนุถ ุงู„ุฏูˆู„
73
00:05:30,040 --> 00:05:33,900
ุงู„ู€ path facility of stroke ุทุจุนุง ุจุฏู†ุง ู†ูู‡ู… ู‡ุฐู‡ ุงู„ู€
74
00:05:33,900 --> 00:05:40,160
slide ุจุดูƒู„ ู…ู‡ู… ุฌุฏุง ุฌุฏุง ุฌุฏุง ุนุดุงู† ู†ุนุฑู ู„ูŠุด time is
75
00:05:40,160 --> 00:05:46,590
very important ุงู„ู€ brain ุจุดูƒู„ the most metabolically
76
00:05:46,590 --> 00:05:51,690
active organ in our body. ู„ูŠุด ู‡ุฐู‡ ุงู„ุญู‚ูŠู‚ุฉุŸ ู„ุฃู†ู‡ he
77
00:05:51,690 --> 00:05:57,170
has high demand for oxygen ุทุจ ู„ูŠุดุŸ ู„ุฃู†ู‡ ู‡ูˆ ูู‚ุท
78
00:05:57,170 --> 00:06:02,170
ุจุดูƒู„ 2% ู…ู† ูˆุฒู† ุฌุณู… ุงู„ุฅู†ุณุงู† ูˆู„ูƒู† ุจูŠุณุชู‡ู„ูƒ ุญูˆุงู„ูŠ 20%
79
00:06:02,170 --> 00:06:06,350
ู…ู† ุงู„ู€ total cardiac output ุจูŠุณุชู‡ู„ูƒ 20% ู…ู† ุงู„ู€ total
80
00:06:06,350 --> 00:06:11,870
oxygen ุชุฎูŠู„ ูƒู„ ู‡ุฐู‡ ุงู„ุฅู…ูƒุงู†ูŠุงุช ุนุดุงู† ู‡ูŠูƒ ู„ู…ุง ุฃู†ุช ูƒู„
81
00:06:11,870 --> 00:06:15,790
ุฏู‚ูŠู‚ุฉ ูˆุฃู†ุช ุจุชุฏุฑุณ ูˆุฃู†ุช ุจุชุฏุฑุณ ูˆุจุชุฑุงุฌุนูŠ ุจุชุฑูˆุญ ุชุทู„ุน
82
00:06:15,790 --> 00:06:19,450
ูˆุชุงูƒู„ูŠ ูˆุชุงุฎุฏูŠ ุดุฎุตูŠุงุช ุฃูˆ ุชุงุฎุฏูŠ .. ู‡ุฐุง ุจูŠู‚ูˆู„ูˆู„ูƒ
83
00:06:19,450 --> 00:06:22,750
ูŠุดูƒ ุฃู† ุงู†ูุฌุนุช ุงู„ุจู†ุช ูˆู„ุง ุงู†ูุฌุน ุงู„ูˆู„ุฏ ู„ุฃ ู‡ุฐุง ุดูŠุก
84
00:06:22,750 --> 00:06:26,810
ุทุจูŠุนูŠ ู„ุฃู†ู‡ ูˆุฃู†ุช ู‚ุงุนุฏ ุชุณุชุฎุฏู… ุฏู…ุงุบูƒ ููŠ ุงู„ุชุฑูƒูŠุฒ ูˆ
85
00:06:26,810 --> 00:06:31,830
ุงู„ุญูุธ ูˆุงู„ุชุญู„ูŠู„ ุฏู…ุงุบูƒ ุจูŠุณุชู‡ู„ูƒ ู…ุนุธู… ุทุงู‚ุฉ ุงู„ู€ oxygen
86
00:06:31,830 --> 00:06:35,950
ููŠ ุงู„ุฌุณู… ูˆู…ุนุธู… ุงู„ูƒุชู„ุฉ ุงู„ุฏู…ูˆูŠุฉ ุงู„ู„ูŠ ุทุงู„ุน ู…ู† ุงู„ู‚ู„ุจ
87
00:06:36,560 --> 00:06:40,680
ูˆู„ู‡ุฐุง ุงู„ุณุจุจ ุงู„ู€ brain needs continuous oxygen and
88
00:06:40,680 --> 00:06:45,880
glucose supply ูู‚ุท ู„ูˆ ุงุชุนุฑุถ ู„ู†ู‚ุต ุงู„ุชุฑูˆูŠุฉ ุงู„ุฏู…ูˆูŠุฉ
89
00:06:45,880 --> 00:06:50,700
ู„ุฏู‚ุงุฆู‚ ู…ุนุฏูˆุฏุฉ ุฑุงุญ ุชู‚ู„ ูˆุธุงุฆู ุงู„ุฃุนุตุงุจ ูˆู…ู…ูƒู† ุฅุฐุง ุงุณุชู…ุฑ
90
00:06:50,700 --> 00:06:53,040
ู‡ุฐุง ุงู„ุดูŠุก ุจุนุฏ ุฃุฑุจุน ุฏู‚ุงุฆู‚ ูŠุตูŠุฑ ููŠ ุนู†ุฏูŠ
91
00:06:53,040 --> 00:06:57,160
irreversible damage ุจุนุถ ุงู„ุนู„ู…ุงุก ู‚ุฏุฑูˆุง ุงู„ุญุฏ ุงู„ุฃู‚ุตู‰
92
00:06:57,160 --> 00:07:00,860
ุงู„ู„ูŠ ู…ู…ูƒู† ูŠุชุญู…ู„ูˆุง ุงู„ุฏู…ุงุบ ู…ู† ุงู„ู†ู‚ุต ุฅู„ู‰ ุฃู‚ู„ ู…ู† 18
93
00:07:00,860 --> 00:07:04,740
ู…ู„ู„ูŠ ู„ูƒู„ 100 ู…ู„ู„ูŠ ุฌุฑุงู… ู…ู† ู…ุงุฏุฉ ุงู„ุฏู…ุงุบ ุฅุฐุง ุตุงุฑ ู‡ุฐุง
94
00:07:04,740 --> 00:07:07,780
ุงู„ุดูŠุก ู…ุนู†ุงู‡ ุฑุงุญ ูŠุตูŠุฑ ููŠ ุงู„ุฏู…ุงุบ ุดูŠุก ุจู†ุณู…ูŠู‡ ุงุญู†ุง
95
00:07:07,780 --> 00:07:12,660
irreversible damage ุงู„ุขู† ุฅุฐุง ุตุงุฑ ู‡ุฐุง ุงู„ุดูŠุก ุจูŠุตูŠุฑ
96
00:07:12,660 --> 00:07:15,600
ุนู†ุฏูŠ ุณู„ุณู„ุฉ ุฃุญุฏุงุซ ุจู†ุณู…ูŠู‡ุง ุงู„ู€ ischemic cascade
97
00:07:15,600 --> 00:07:18,780
ischemic cascade ุฃู†ู‡ ุจูŠุตูŠุฑ ููŠ ุงู† ischemic
98
00:07:18,780 --> 00:07:22,060
process occurs at cellular level ุนู„ู‰ ู…ุณุชูˆู‰
99
00:07:22,060 --> 00:07:25,200
ุงู„ุฎู„ุงูŠุง ุจุชุจุฏุฃ ุชุตูŠุฑ ุงู„ุชุบูŠุฑุงุช it happens within
100
00:07:25,200 --> 00:07:29,550
seconds to minutes of losing glucose and oxygen It
101
00:07:29,550 --> 00:07:32,310
begins with losing cellular electrophysiological
102
00:07:32,310 --> 00:07:36,610
functionsุŒ ุฅุฐุง ุชููƒุฑูŠู† ุงู„ู€ ATPsุŒ ุงู„ุนููˆู‹ุงุŒ ุงู„ู€ action
103
00:07:36,610 --> 00:07:41,210
potentialsุŒ ุงู„ู€ cell metabolism ุจุชุชุญูˆู„ ู…ู† aerobic ู„ู€
104
00:07:41,210 --> 00:07:44,190
AnaerobicุŒ ุจูŠุตูŠุฑ ุนู†ุฏู†ุง depletion ููŠ ุงู„ู€ ATP storeุŒ
105
00:07:44,190 --> 00:07:48,990
ุจูŠุตูŠุฑ ููŠ ุนู†ุฏู†ุง ุงู„ู€ ion pumps ุจุชูุดู„ุŒ ุจูŠุตูŠุฑ ููŠ ุนู†ุฏู†ุง
106
00:07:48,990 --> 00:07:53,150
ุงู„ุชุฌู…ูŠุน ู„ู„ูƒุงู„ุณูŠูˆู… ูˆุงู„ุตูˆุฏูŠูˆู… ููŠ ุฏุงุฎู„ ุงู„ุฎู„ูŠุฉุŒ ุจุจุฏุฃ ููŠ
107
00:07:53,150 --> 00:07:58,250
ุนู†ุฏูŠ ุชูุงุนู„ุงุช ุจู†ุดุทู‡ุง ุงู„ู€ calcium-mediated cytotoxic
108
00:07:58,250 --> 00:08:02,490
reactions ุชุจุฏุฃ ุชุดุชุบู„ ุจุชุทู„ุนู„ูŠ ูƒู„ ุงู„ู€ excitatory
109
00:08:02,490 --> 00:08:06,450
neurotransmitters ุฏูŠ glutamate ูˆุจุชุทู„ุนู„ูŠ ุงู„ู€ ุงู†ุฒูŠู…ุงุช
110
00:08:06,450 --> 00:08:10,530
ุฒูŠ ุงู„ู€ proteases ูˆุงู„ู€ endonucleases ูˆุงู„ููˆุณููˆู„ุงูŠ
111
00:08:10,530 --> 00:08:14,670
ุจูŠุฒ ูƒู„ ู‡ุฏูˆู„ ุจูŠุคุฏูˆุง ุฅู„ู‰ ุฐูˆุจุงู† ุงู„ุฎู„ูŠุฉ ุงู„ู€ cell lysis
112
00:08:14,670 --> 00:08:18,830
ุทุจ ู„ู…ุง ุงู„ุฎู„ูŠุฉ ุฐุงุจุช ุจูŠุทู„ุน ู…ู†ู‡ุง free radicals
113
00:08:18,830 --> 00:08:22,630
free radicals ุณุงู…ุฉ ู„ู„ุฎู„ุงูŠุง ุงู„ู…ุญูŠุทุฉ ุจูŠู‡ุง ูู…ู…ูƒู†
114
00:08:22,630 --> 00:08:25,190
ูŠุนู…ู„ ุงู„ู€ neuronal damageุŒ glial damageุŒ
115
00:08:25,190 --> 00:08:29,130
irreversible injury ุจุงู„ุฅุถุงูุฉ ู„ุชุฌู…ุน ุงู„ุณูˆุงุฆู„ ุงู„ู„ูŠ ู‡ูˆ
116
00:08:29,130 --> 00:08:37,310
ุจูŠุนู…ู„ brain edema ููŠ
117
00:08:37,310 --> 00:08:40,910
ุนู†ุฏู†ุง ู…ุตุทู„ุญ ู…ู‡ู… ุฌุฏุง ุจุชุนู„ู‚ ุจุงู„ุฅุณูƒูŠู…ูŠุง ุงุณู…ู‡
118
00:08:40,910 --> 00:08:44,490
ุงู„ุฅุณูƒูŠู…ูŠูƒ ุจู†ุงู…ุจุฑุง ischemic penumbra ู„ู…ุง ุจูŠุตูŠุฑ ููŠ
119
00:08:44,490 --> 00:08:48,630
ุนู†ุฏู†ุง acute occlusion it will lead to heterogeneous
120
00:08:48,630 --> 00:08:52,410
regions of ischemia ูŠุนู†ูŠ ู…ู†ุงุทู‚ ู…ุฎุชู„ูุฉ ู…ู†ุงุทู‚ ุจูŠุตูŠุฑ
121
00:08:52,410 --> 00:08:56,450
ููŠู‡ุง ู†ู‚ุต ูƒุงู…ู„ ู„ู„ุชุฑูˆูŠุฉ ุงู„ุฏู…ูˆูŠุฉ ูˆู‡ุฐู‡ ุจูŠุณู…ูŠู‡ุง the
122
00:08:56,450 --> 00:08:59,630
core ู‡ุฐุง ุงู„ู€ region without any blood flow ูˆุงู„ุฎู„ุงูŠุง
123
00:08:59,630 --> 00:09:03,930
ุจุชู…ูˆุช ุฎู„ุงู„ ุฏู‚ุงุฆู‚ ุฃุฑุจุน ุฏู‚ุงุฆู‚ ุฎู…ุณ ุฏู‚ุงุฆู‚ ู„ู„ุฎู„ุงูŠุง ุฎู„ุงุต
124
00:09:03,930 --> 00:09:07,550
finito finished ูˆู„ูƒู† ููŠ ุนู†ุฏูŠ ู…ู†ุทู‚ุฉ ุซุงู†ูŠุฉ ุงุณู…ู‡ุง ุงู„ู€
125
00:09:07,550 --> 00:09:13,550
penumbra ู‡ู†ุง ุงู„ุฃู†ุณุฌุฉ ุจุชุธู„ ููŠู‡ุง marginal perfusion
126
00:09:13,550 --> 00:09:18,870
ุฌุงูŠ ู…ู† ู…ู†ุงุทู‚ ุทุฑููŠุฉ ู†ุชูŠุฌุฉ ุจุนุถ ุงู„ู€ collateral's ุฒูŠ ู…ุง
127
00:09:18,870 --> 00:09:21,770
ุดุงูŠููŠู† ููŠ ุงู„ุตูˆุฑุฉ ู‡ู†ุง ููŠ ุฌุงูŠ ุนู†ุฏูŠ collateral's
128
00:09:21,770 --> 00:09:25,830
ุจุชุบุฐู‰ ุจุนุถ ุงู„ู…ู†ุงุทู‚ ูููŠ ุนู†ุฏูŠ ุฃู†ุง ู…ู†ุทู‚ุฉ ู…ุซู„ุง ู‡ุฐู‡
129
00:09:25,830 --> 00:09:30,130
ุงู„ู…ู†ุทู‚ุฉ ู‡ุฐู‡ ุงู„ู…ู†ุทู‚ุฉ core ุงู„ู…ู†ุทู‚ุฉ ุงู„ุจูŠุถุงุก ูˆู„ูƒู† ู‡ุฐู‡
130
00:09:30,130 --> 00:09:32,990
ุงู„ู…ู†ุทู‚ุฉ ุงู„ู„ูŠ ู„ูˆู†ู‡ุง ุดูˆูŠุฉ ู…ุง ุจูŠู† ุงู„ุฃุจูŠุถ ูˆ ู…ุง ุจูŠู†
131
00:09:32,990 --> 00:09:36,550
ุงู„ู„ูˆู† ุงู„ุทุจูŠุนูŠ ู‡ูŠ ู‡ุฐู‡ ุงู„ู…ู†ุทู‚ุฉ ุงู„ู„ูŠ ุจู†ุณู…ูŠู‡ุง ุงู„ู€
132
00:09:36,550 --> 00:09:39,970
penumbra ุงู„ู„ูŠ ุนู„ูŠู‡ุง ูƒู„ ุงู„ุดุบู„ ุนุดุงู† ู†ุญุงูˆู„ ู†ู†ู‚ุฐู‡ุง
133
00:09:39,970 --> 00:09:44,330
ูˆู‡ุฐู‡ ุงู„ู…ู†ุทู‚ุฉ ู„ูˆ ุงุณุชุทุนู†ุง ุฃู†ู‡ ู†ู†ู‚ุฐู‡ุง ุจู‚ุฏุฑ ุงู„ุงู…ูƒุงู†
134
00:09:44,650 --> 00:09:49,190
ุจุฅุฐู† ุงู„ู„ู‡ ู…ู…ูƒู† ู†ุญุงูˆู„ ู†ู‚ู„ู„ ุชุฃุซูŠุฑ ุงู„ุฌู„ุทุฉ ุจุดูƒู„ ูƒุจูŠุฑ
135
00:09:49,190 --> 00:09:55,610
ุงู„ุขู† ูƒู„ ู…ุง ุจู†ุณุฑู‘ุน ุฃูƒุซุฑ ูƒู„ ู…ุง ุจู†ู‚ู„ู„ ุชุฃุซูŠุฑ ุงู„ุฌู„ุทุฉ ุนู„ู‰
136
00:09:55,610 --> 00:09:59,950
ุงู„ุฃูˆุนูŠุฉ ุชุจุน ุงู„ุฏู…ุงุบ ุจุดูƒู„ ุฃูƒุจุฑ ูˆู…ู…ูƒู† ููŠ ุจุนุถ ุงู„ุญุงู„ุงุช
137
00:09:59,950 --> 00:10:04,910
ู†ู†ุฌุญ ููŠ ุฃู†ู‡ ู†ุนูˆุฏ ุจุงู„ู…ุฑูŠุถ ุฅู„ู‰ ุงู„ูˆุถุน ุงู„ุทุจูŠุนูŠ ู‚ุจู„
138
00:10:04,910 --> 00:10:10,270
ุงู„ุฌู„ุทุฉ ุงู„ุขู† ู‡ุฐุง ุงู„ู…ูˆุถูˆุน ูŠุนู†ูŠ ู…ุง ุจุฏูŠุด ุฃู†ุง ุฃุทุฑู‚ ููŠู‡
139
00:10:10,270 --> 00:10:15,070
ุงู„ู„ูŠ ู‡ูˆ blood supply ู‡ุฐุง ุฃุฎุฐุชู‡ ููŠ ุงู„ู€ anatomy ูุฃูƒูŠุฏ
140
00:10:15,070 --> 00:10:19,470
ูŠุนู†ูŠ ุฅู†ุดุฑุญ ู„ูƒู… ุจุชูุตูŠู„ ูˆู„ูƒู† ุจุณูˆุก ุจุณ ู†ุฐูƒุฑ ุงุญู†ุง ููŠ
141
00:10:19,470 --> 00:10:23,410
ุงู„ุฃุดูŠุงุก ุงู„ู…ู‡ู…ุฉ ุฃู†ู‡ ููŠ ุนู†ุฏู†ุง ุงู„ุชุฑูˆูŠุฉ ุงู„ุฏู…ุงุบูŠุฉ ุชูŠุฌูŠ
142
00:10:23,410 --> 00:10:26,950
ู…ู† ุงู„ู€ left ูˆ ุงู„ู€ right common carotid ูˆ ุจุฑุถู‡ ู…ู† ุงู„ู€
143
00:10:26,950 --> 00:10:30,810
vertebral artery ูŠุนู†ูŠ ููŠ ุนู†ุฏูŠ ุงู„ู€ .. ุงู„ู€ .. ุงู„ู€ left
144
00:10:30,810 --> 00:10:33,970
ูˆ ุงู„ู€ right common carotid ูˆ ููŠ ุนู†ุฏ ุงู„ู€ vertebral
145
00:10:33,970 --> 00:10:37,930
arteries internal carotid ุจุจุฏุฃ ุจุบุฒูŠู„ุฉ ุงู„ู€ antenna
146
00:10:37,930 --> 00:10:41,190
two third of the cerebrum except parts of temporal
147
00:10:41,190 --> 00:10:44,810
and occipital lobe ุงู„ุจุฑุชุจุฑูˆ ุจุงุฒูŠู„ุฑ ุงู„ู€ circulation
148
00:10:44,810 --> 00:10:48,750
ุจุชุบุฒูŠู„ ุงู„ู€ two-fifth of cerebrum, cerebellum and
149
00:10:48,750 --> 00:10:54,950
brainstem ุงู„ุขู† ู‡ุฐู‡ ุงู„ุฃุดูŠุงุก ุถุฑูˆุฑูŠุฉ ููŠ ู…ุนุฑูุฉ ุงู„ู€
150
00:10:54,950 --> 00:10:58,730
affected region ูŠุนู†ูŠ ู„ูˆ ุฃู†ุง ููŠ ุนู†ุฏูŠ ู…ุซู„ุง ูˆุงู„ู„ู‡ ุงู„ู€
151
00:10:58,730 --> 00:11:02,490
region ู‡ุฐุง ู‡ูˆ ุงู„ู„ูŠ ุฃุซุฑ ู ุฃู†ุง ุจุฏูŠ ุฃุจุญุซ ููŠ ุงู„ู€ blood
152
00:11:02,490 --> 00:11:06,710
supply ุงู„ู„ูŠ ู‡ูˆ ูŠุฌูŠ ู…ู†ู‡ ู‚ุฏ ูŠูƒูˆู† ุฌุงุจ ู„ูŠ ุงู„ุฎุณุงุฑุฉ ู…ู†
153
00:11:06,710 --> 00:11:10,750
ุงู„ู‚ู„ุจ ุฃูˆ ู‚ุฏ ูŠูƒูˆู† ุงุฌุช ู…ู† ูˆุฑุง ุฃูˆ ู‚ุฏ ุชูƒูˆู† ุงุฌุช ู…ู† ุฏุงุฎู„
154
00:11:11,050 --> 00:11:15,630
ุงู„ุฏู…ุงุบ ุฃูˆ ุชูƒูˆู† ุฌุฒุก ู…ู†ู‡ุง ุงู†ูุฌุฑ ู„ุง ุณู…ุญ ุงู„ู„ู‡ ุทุจุนุง
155
00:11:15,630 --> 00:11:18,810
ุงุญู†ุง ู‚ู„ู†ุง ู…ุง ุจุฏู†ุงุด ู†ูุตู„ ููŠู‡ู… ุงู„ู€ anterior cerebral
156
00:11:18,810 --> 00:11:22,590
artery ูˆ ุงู„ุชูˆุฒูŠุน ู‡ุฐู‡ ุทุจุนุง ู„ุฃู†ู‡ ุฅู†ุดุฑุญ ููŠ ุงู„ู€
157
00:11:22,590 --> 00:11:27,850
anatomy ูˆ ุนุฏุฉ ู…ุฑุงุช ูˆ ุฐูƒุฑู†ุง ุฃู† ุงู„ู€ anterior ู…ู† ุงู„ุงุณู…
158
00:11:27,850 --> 00:11:32,730
ุจูŠุบุฐูŠ ุฃูƒุซุฑ ุงู„ู€ frontal lobe ูู„ูˆ ุฃู†ู‡ ุดุฎุต ุตุงุฑ ููŠ ุนู†ุฏู‡
159
00:11:32,730 --> 00:11:36,410
ุฃูŠ ู…ุดูƒู„ุฉ ู ุฃู†ุง ุจุฏู‡ ุฃุธู† ุฃู†ู‡ ููŠ ุงู„ู€ frontal lobe ุทุงู„ู…ุง
160
00:11:36,410 --> 00:11:39,090
ุจูŠุจู‚ู‰ ุดูƒ ุฃู†ุง ููŠ ุงู„ู€ anterior cerebral artery ุงู„ู€
161
00:11:39,090 --> 00:11:42,450
middle cerebral artery ู‡ูˆ ู‡ุฐุง ุงู„ู€ largest branch of
162
00:11:42,450 --> 00:11:45,870
internal carotid ู‡ุฐุง ุจูŠุบุฐูŠ portion of frontal
163
00:11:45,870 --> 00:11:49,570
portion of temporal portion of parietal ูŠุนู†ูŠ ู…ุนุธู…
164
00:11:49,570 --> 00:11:53,750
ุงู„ุฃุฌุฒุงุก ููŠ ุงู„ุฏู…ุงุบ ุจูŠุบุฐูŠู‡ุง ู‡ูˆ ู‡ุฐุง the most commonly
165
00:11:53,750 --> 00:11:58,440
occluded artery in stroke ูŠุจู‚ู‰ ู„ูˆ ุณุฃู„ุช ูˆุงู„ู„ู‡
166
00:11:58,440 --> 00:12:01,580
ููŠ ุนู†ุฏูŠ anterior ูˆ middle ูˆ cerebral ุฃู† ู‡ูˆ ูˆ ุฃู†ุช
167
00:12:01,580 --> 00:12:04,900
ู…ุด ุนุงุฑู ุงู„ุฌูˆุงุจ ุงู„ู€ middle ู‡ูˆ ุงู„ู€ most probably
168
00:12:04,900 --> 00:12:08,340
occluded ู„ุฃู†ู‡ ู‡ูˆ ุงู„ู€ most commonly occluded artery
169
00:12:08,340 --> 00:12:13,920
ุงู„ู€ posterior ู‡ุฐุง ูŠุนู†ูŠ ุจูŠุบุฐูŠ ู„ูŠ ุงู„ู€ .. ุงู„ู€ temporal ูˆ
170
00:12:13,920 --> 00:12:18,420
ุงู„ู€ occipital lobe ูˆ .. ูˆ ุจูŠุนู…ู„ูŠ visual disturbances
171
00:12:18,420 --> 00:12:21,060
ู„ุฃู†ู‡ ููŠ ุงู„ุฃุณุงุณ ุจูŠุบุฐูŠ ุงู„ู…ู†ุงุทู‚ ุชุจุนูŠ ุงู„ุฑุคูŠุฉ
172
00:12:22,580 --> 00:12:25,500
Lenticulostriate arteries ู‡ุฏูˆู„ penetrating
173
00:12:25,500 --> 00:12:28,620
arteries ุฏุงุฆู…ุง ุดุงูŠููŠู† ููŠ ุงู„ุตูˆุฑุฉ ุทุงู„ุนูŠู† ู…ู† ุงู„ู€
174
00:12:28,620 --> 00:12:31,660
middle cerebral artery ูˆ ู‡ุฏูˆู„ ุจูŠุบุฒูˆุง ุงู„ู…ู†ุงุทู‚ deep
175
00:12:31,660 --> 00:12:36,260
ุฅุฐุง ูุงูƒุฑูŠู† ููŠ ู„ู…ุง ุดุฑุญู†ุง ุงู„ู€ basal ganglia ููŠ ุงู„ูุตู„
176
00:12:36,260 --> 00:12:40,720
ุงู„ุซุงู†ูŠ ุฐูƒุฑู†ุง ุนู† ุงู„ู€ sub cortical areas ู‡ุฏู‰ ู…ู†ุงุทู‚
177
00:12:40,720 --> 00:12:45,240
ุนู…ูŠู‚ุฉ ุฌุฏุง ููŠ ุฏุงุฎู„ ุงู„ุฏู…ุงุบ ุนู†ุฏ ู…ู†ุทู‚ุฉ ุงู„ุงู†ุด ู„ูˆ ุฏูŠุจ
178
00:12:45,240 --> 00:12:50,590
okay ูˆ ุจูŠุบุฐูŠู‡ุง ุงู„ู€ lenticulostriate arteries ู‡ุฐู‡ ุงู„ู€
179
00:12:50,590 --> 00:12:54,370
.. ุงู„ู€ .. ุงู„ู€ arteries ุจุนุถ ุงู„ุฃุญูŠุงู† ู„ู…ุง ูŠุฒูŠุฏ ุงู„ุถุบุท
180
00:12:54,370 --> 00:12:58,570
ุจูŠุตูŠุฑ ููŠู‡ุง ุงู†ูุฌุงุฑุงุช ุจุนุถ ุงู„ุฃุญูŠุงู† ุจูŠุตูŠุฑ ููŠู‡ุง
181
00:12:58,570 --> 00:13:03,270
ุงู†ุณุฏุงุฏุงุช ูˆู„ูƒู† ุงู„ู€ .. ุงู„ู€ .. ุงู„ู€ stroke ุงู„ู„ูŠ ุจุชู†ุชุฌ
182
00:13:03,270 --> 00:13:06,950
ุนู†ู‡ู… ุจู†ุณู…ูŠู‡ุง ุงู„ู€ lacunar stroke ูˆู‡ูŠ ู„ู‡ุง ุงู„ู€ best
183
00:13:06,950 --> 00:13:13,090
prognosis ู„ูŠุดุŸ ู„ุฃู†ู‡ ููŠ ุฃูƒุซุฑ ู…ู† ุดุฑูŠุงู† ุฌู†ุจ ุจุนุถ ูุญุชู‰
184
00:13:13,090 --> 00:13:16,450
ู„ูˆ ู‡ุฐุง ุงู†ูุฌุฑ ููŠ ู…ู†ุทู‚ุฉ ุซุงู†ูŠุฉ ุจุชุบุฐูŠู‡ุง ุญุชู‰ ู„ูˆ ู‡ุฐุง ุณุฏุฏ
185
00:13:16,450 --> 00:13:21,940
ููŠ ุดุฑูŠุงู† ุซุงู†ูŠ ุฌู†ุจู‡ ุจูŠุบุฐูŠู‡ุง ูู‡ุฐุง ุจุชุฏูŠู‡ุง huge
186
00:13:21,940 --> 00:13:26,520
collateral's ู„ุฃู† ู†ุญูƒูŠ ุนู† ุงู„ู€ clinical categories
187
00:13:26,520 --> 00:13:29,440
ุจุงู„ู€ general ููŠ ุนู†ุฏูŠ ischemic stroke ููŠ ุนู†ุฏูŠ
188
00:13:29,440 --> 00:13:33,140
hemorrhagic stroke ุงู„ู€ ischemic ุจุชุดูƒู„ ู„ูŠ 80% ุงู„ู€
189
00:13:33,140 --> 00:13:39,380
hemorrhagic ุจุชุดูƒู„ ู„ูŠ ุญูˆุงู„ูŠ ู…ู† 10 ู„ 15% ุงู„ู€ ischemic
190
00:13:39,380 --> 00:13:44,120
stroke ุทุจุนุง ููŠ ุชุญุชู‡ุง ุจูŠุฌูŠ ุฃูƒุซุฑ ู…ู† ูุฑุน ููŠ ุจูŠุฌูŠ
191
00:13:44,120 --> 00:13:49,320
ุชุญุชู‡ุง ุฐูƒุฑู†ุง ุฃู† ููŠ ุนู†ุฏูŠ two main categories
192
00:13:49,320 --> 00:13:51,920
ischemic ูˆ hemorrhagic ุชุญุช ุงู„ู€ ischemic ุจูŠุฌูŠ ููŠ
193
00:13:51,920 --> 00:13:54,720
ุนู†ุฏู†ุง transient ischemic attack ููŠ ุนู†ุฏู†ุง
194
00:13:54,720 --> 00:13:57,540
thrombotic CVA ููŠ ุนู†ุฏู†ุง embolic ูˆ ููŠ ุนู†ุฏู†ุง lacunar
195
00:13:57,540 --> 00:14:03,400
ุงู„ุขู† ู†ุจุฏุฃ ูˆุงุญุฏุฉ ูˆุงุญุฏุฉ ููŠู‡ู… ู‡ุฏูˆู„ ุชุญุช ุงู„ู€ ischemic ุฃูˆ
196
00:14:03,400 --> 00:14:08,520
ุงู„ู€ TIA ู‡ุฐู‡ ุจู†ุณู…ูŠู‡ุง mini stroke ุฃูˆ TIA ุทุจุนุง ููŠ
197
00:14:08,520 --> 00:14:13,960
ุงู„ู…ุงุถูŠ ูƒุงู†ูˆุง ุจูŠุนุฑููˆู‡ุง ุนู„ู‰ ุฃู†ู‡ ูˆุฌูˆุฏ ุฃุนุฑุงุถ ู„ู€ stroke ููŠ
198
00:14:13,960 --> 00:14:18,380
ูุชุฑุฉ ุฃู‚ู„ ู…ู† ุฃุฑุจุน ูˆุนุดุฑูŠู† ุณุงุนุฉ ูˆู„ูƒู† ุงู„ุขู† ุฎู„ุงุต ูŠุนู†ูŠ
199
00:14:18,380 --> 00:14:24,840
ุทุงู„ู…ุง ุฃู†ู‡ ููŠ ูุชุฑุฉ ู‚ุตูŠุฑุฉ ูˆู„ู… ุชุณุชู‚ุฑ ูƒู…ุง ู‡ูŠ ูŠุนู†ูŠ ุชุนูˆุฏ
200
00:14:24,840 --> 00:14:28,400
ุฅู„ู‰ ุงู„ูˆุถุน ุงู„ุทุจูŠุนูŠ ูู‡ุฐู‡ ูŠุทู„ู‚ ุนู„ูŠู‡ุง TIA ุงู„ู„ูŠ ู‡ูŠ ู…ุณู…ูŠุงุช
201
00:14:28,400 --> 00:14:33,480
ุซุงู†ูŠุฉ ู…ู† stroke and gene of the brain ูˆู„ูƒู† ุฃู‡ู…ูŠุชู‡ุง
202
00:14:33,480 --> 00:14:39,020
ู„ุง ุชูƒู…ู† ููŠ ุฃู†ู‡ ู‡ูŠ ุตุงุฑ ุนู†ุฏ ุงู„ุดุฎุต ุฃุนุฑุงุถ ูˆู„ูƒู† ู‡ุฐู‡
203
00:14:39,020 --> 00:14:43,020
ุงู„ุฃุนุฑุงุถ ุงุฎุชูุช ุฃู‡ู…ูŠุชู‡ุง ุฃู† ู‡ุฐุง ุงู„ุดุฎุต ู…ุนุฑุถ ู„ุฌู„ุทุฉ
204
00:14:43,020 --> 00:14:47,400
ุญู‚ูŠู‚ูŠุฉ ุฎู„ุงู„ ุฃุฑุจุน ุฃุณุงุจูŠุน ุจุนุฏ ุงู„ุฌู„ุทุฉ ู‡ุฐู‡ ุงู„ุชุญุฐูŠุฑูŠุฉ
205
00:14:47,400 --> 00:14:52,060
ูˆู„ู‡ุฐุง ุงู„ุณุจุจ ูŠุญุชุงุฌ ุฅู„ู‰ ุฑุนุงูŠุฉ ูˆ precautions
206
00:14:53,430 --> 00:14:57,430
Thrombotic CVA ู‡ุฐูŠ ุจุชุดูƒู„ 60% of all ischemic
207
00:14:57,430 --> 00:15:01,870
strokes 70% ุจุชูŠุฌูŠ ููŠ ุงู„ู€ large vessels ูˆ 30% ููŠ ุงู„ู€
208
00:15:01,870 --> 00:15:06,650
small vessels ู‡ุฐูŠ ุจูŠุตูŠุฑ ููŠู‡ ุฃู†ู‡ ุฃุซุฑ ุงุณูƒู„ูŠุฑุณูŠุณ ู‚ุฏ
209
00:15:06,650 --> 00:15:10,270
ูŠูƒูˆู† ุงู„ุดุฎุต ููŠู‡ ุนู†ุฏู‡ thrombogenic factors ุฒูŠ injury
210
00:15:10,270 --> 00:15:15,170
ููŠ ุงู„ู€ endothelial cellsุŒ platelet activation ูŠุนู†ูŠ
211
00:15:15,170 --> 00:15:19,600
ููŠ ุญุงู„ุงุช ุงู„ู€ hypercoagulable state ู…ุซู„ุง ููŠ ุฅู† ู…ุนุงู‡ุง
212
00:15:19,600 --> 00:15:24,420
activation of clotting cascade ููŠ stasis ุนู†ุฏูŠ
213
00:15:24,420 --> 00:15:29,700
frequently arise from rupture plaque ูŠุนู†ูŠ ู‡ุฐุง
214
00:15:29,700 --> 00:15:33,280
ุงู„ุชุฌู…ุน ุงู„ุตูุงุฆุญ ุงู„ุฏู‡ู†ูŠุฉ ุงู„ู„ูŠ ุจุชูƒูˆู† ู…ุชุฑุงูƒู…ุฉ ููŠ ุฌู„ุจ
215
00:15:33,280 --> 00:15:38,520
ุงู„ุดุฑุงูŠูŠู† ุฌุฒุก ู…ู†ู‡ุง ู…ุน ุณุฑูŠุงู† ุงู„ุฏู… ุจูŠุตูŠุฑ ุจูู„ุช ูˆ
216
00:15:38,520 --> 00:15:43,560
ุจุชุทู„ุน ูˆ ุชุชุญุฑูƒ ูˆ ู…ู…ูƒู† ุชุตู„ ู„ู„ุฏู…ุงุบ ุนู†ุฏ ุตุบุงุฑ ุงู„ุณู† ู„ุงุฒู…
217
00:15:43,560 --> 00:15:48,290
ุงุญู†ุง ู†ุดูƒ ููŠ ู…ุดุงูƒู„ ููŠ ุชุฌู„ุท ุงู„ุฏู… ู†ุดูƒ ููŠ aortic
218
00:15:48,290 --> 00:15:53,350
dissection ูˆ vasoconstriction ูˆู„ูƒู† ู…ู…ูƒู† ู†ุดูƒ ุจุฑุถู‡
219
00:15:53,350 --> 00:15:56,190
ุฃู† ุงู„ู…ุฑูŠุถ ููŠู‡ endovascolitis ูˆู‡ูŠ ุงู„ู„ูŠ ู‚ุฏุช ุฅู„ู‰
220
00:15:56,190 --> 00:16:00,730
ุงู„ุฌู„ุทุฉ ุจุณุจุจ ุชุนุงุทูŠ ุจุนุถ ุงู„ู…ุฎุฏุฑุงุช ุฃูˆ ุจุนุถ ุงู„ู…ู†ุจู‡ุงุช
221
00:16:00,730 --> 00:16:05,670
ูˆุงู„ู…ุญุฑู…ุงุช ุงู„ู€ embolic stroke ุจุชุดูƒู„ ู„ุนุดุฑูŠู† ููŠ ุงู„ู…ูŠุฉ
222
00:16:05,670 --> 00:16:08,870
of all is chemical strokes ู…ุตุฏุฑู‡ุง ุงู„ุฃุณุงุณูŠ ุจูŠูƒูˆู† ุงู„ู€
223
00:16:08,870 --> 00:16:12,970
heart ููŠ ุนู†ุฏ ุงู„ู†ุงุณ ุงู„ู„ูŠ ุนู†ุฏู‡ู… AFindolescent MI,
224
00:16:13,150 --> 00:16:17,390
prostatic valve ู„ู…ุง ู†ุถุน ู„ู‡ ุตู…ุงู… ุตู†ุงุนูŠ ุนุฑุถุฉ ุฃู†ู‡ ูŠูƒูˆู†
225
00:16:17,390 --> 00:16:22,350
ุฎุทุฑุงุช ุญูˆุงู„ูŠู‡ ูˆ ุชุทู„ุน ุจุนุฏ ูƒุฏู‡ ู…ู† ุงู„ุดุฑุงูŠูŠู† ุงู„ู„ูŠ ุทุงู„ุน
226
00:16:22,350 --> 00:16:25,230
ู…ู† ุงู„ู‚ู„ุจ ูˆ ุชุตู„ ู„ู„ู€ internal carotid ู…ู†ู‡ ุฅู„ู‰ ุงู„ุฏู…ุงุบ,
227
00:16:25,790 --> 00:16:28,830
vulvar disease, endocarditis, myorthrombosis,
228
00:16:28,970 --> 00:16:32,050
dilated cardiomyopathy ูƒู„ ู‡ุฐู‡ ุงู„ุฃุดูŠุงุก ุฃูˆ ุชุชูƒูˆู† ููŠ
229
00:16:32,050 --> 00:16:36,830
ุงู„ู€ arteries ุจุงู„ุฐุงุช ุงู„ู€ big arteries ู†ุชูŠุฌุฉ ูƒูˆู„ูŠุณุชุฑูˆู„
230
00:16:36,830 --> 00:16:42,750
ุงู†ุจู„ุงูŠ ุฃูˆ ุฒูŠ ู…ุง ู‚ู„ู†ุง ุจู„ุงูƒ ุดุฑุงุจู†ู„ุฒ ู‡ุฐู‡ ุงู„ู…ุฑุถุฉ ุชุตุฏุฏ
231
00:16:42,750 --> 00:16:46,550
ู„ู€ very sudden onset ู„ุฃู† ู‚ุทุนุฉ ุฏู„ุช ุชุฌุฑูŠ ููŠ ุงู„ุฏู…
232
00:16:46,550 --> 00:16:50,950
ูˆุจุนุฏูŠู† ุชุตุฏุฏ ููŠ ู…ูƒุงู† ุฏู‚ูŠู‚ ุฌุฏุง ูˆู„ูƒู† ู‡ุฏูˆู„ ุงู„ู…ุฑุถู‰ ุนุงุฏุฉ
233
00:16:50,950 --> 00:16:55,690
ุจูŠูƒูˆู† ููŠ ุนู†ุฏู‡ู… ุฌู„ุทุงุช ุณุงุจู‚ุฉ ุจุชุธู‡ุฑ ููŠ ุงู„ุณูˆุงุฑ ูŠุดุนุฑ
234
00:16:55,690 --> 00:17:00,710
ุงู„ู„ูŠ ูƒูˆู†ู‡ infection ุจุชุดูƒู„ ุจุฑุถู‡ 20% ู…ู† ุงู„ู€ chemical
235
00:17:00,710 --> 00:17:04,250
strokes ูˆู‡ุฐู‡ ุจูŠุตูŠุฑ ููŠ ุงู† ุฃูƒู„ูˆุฌูŠู† of penetrating
236
00:17:04,250 --> 00:17:07,830
branches ููŠ ุงู„ู€ middle cerebral arteries ุฃูˆ ุงู„ู„ูŠ
237
00:17:07,830 --> 00:17:11,360
ุทุงู„ุน ู…ู† ุณูŠุฑูƒู„ูˆููˆู„ูŠุณ ุทุจุนุง ู‡ุฏูˆู„ ุงู„ู€ penetrating
238
00:17:11,360 --> 00:17:15,640
arteries ู‚ู„ู†ุง ุฑู‚ูŠู‚ุฉ ุฌุฏุง ุฌุฏุง ูู…ู† ุงู„ุณู‡ู„ ุฃู† ูŠุตูŠุฑ
239
00:17:15,640 --> 00:17:19,680
ููŠู‡ุง ุชุฌู…ุนุงุช ูˆู…ู† ุงู„ุณู‡ู„ ุฃู† ู‡ูŠ ุชุชุดุฏู ู…ู†ู‡ุง ู‚ุทุน ุจุงู„ุฐุงุช
240
00:17:19,680 --> 00:17:23,340
ุฅุฐุง ุตุงุฑ ููŠ ุนู†ุฏูŠ microarthroma ุฃูˆ hyaluronosis ุฃูˆ
241
00:17:23,340 --> 00:17:28,820
fibrinoid degeneration ุฃูˆ amyloid accumulation ููŠ
242
00:17:28,820 --> 00:17:32,420
ุงู„ุฌุฏุงุฑ ู‡ุฐู‡ ุงู„ุชุฌู…ุนุงุช ุงู„ุบูŠุฑ ุทุจูŠุนูŠุฉ ููŠ ุงู„ุฌุฏุงุฑ ุชุจุน
243
00:17:32,420 --> 00:17:37,260
ู‡ุฐู‡ ุงู„ุฃูˆุนูŠุฉ ุงู„ุฏู‚ูŠู‚ุฉ ุจุชุถุนูู‡ุง ู…ู…ูƒู† ุชุฎู„ูŠู‡ุง ุชุณุฏุฏ ู„ุง ุณู…ุญ
244
00:17:37,260 --> 00:17:42,940
ุงู„ู„ู‡ ู‡ุฐู‡ ู‡ูˆ ุงู„ุฃูุถู„ ุงู„ู€ prognosis ูˆ ุฐูƒุฑู†ุง ุงุญู†ุง ุงู„ุณุจุจ
245
00:17:42,940 --> 00:17:47,320
ู„ูŠุดุŸ ู„ุฃู†ู‡ ูƒุซุฑุฉ ุงู„ู€ collateral ู†ูŠุฌูŠ ู†ุญูƒูŠ ุนู† ุงู„ู€
246
00:17:47,320 --> 00:17:50,020
hemorrhage ููŠ ุนู†ุฏูŠ ุฃู†ุง subarachnoid hemorrhage ููŠ
247
00:17:50,020 --> 00:17:53,240
intra cerebral hemorrhage ุงู„ู€ subarachnoid occurs
248
00:17:53,240 --> 00:17:56,440
when a vessel on the brain surface ruptures and
249
00:17:56,440 --> 00:18:00,540
bleeds into the space ูˆู„ูƒู† not inside the brain
250
00:18:01,110 --> 00:18:04,110
ูˆู‡ุฐู‡ ุจุชุดูƒู„ 7% ู…ู† ุงู„ู€ All Strokes ุฃู…ุง ุงู„ู€
251
00:18:04,110 --> 00:18:06,730
Intracerebral Hemorrhage ูู‡ุฐู‡ ุจูŠุตูŠุฑ ููŠ ุนู†ุฏูŠ
252
00:18:06,730 --> 00:18:11,410
defective artery or aneurysm ุจู†ูุฌุฑ ุจูŠุบุฑู‚ู„ ุงู„ู…ู†ุทู‚ุฉ
253
00:18:11,410 --> 00:18:16,050
ุงู„ู…ุญูŠุทุฉ ูˆู‡ุฐู‡ ุจุชุดูƒู„ ู…ู† 10% ู„ 15% ูŠุนู†ูŠ ู‡ูŠูƒ ุฌู…ุนู†ุง ุงู„
254
00:18:16,050 --> 00:18:20,210
20% ูˆุธู„ุช 80% ู„ู€ ุงู„ ischemic strokes ู‡ุฐู‡ high
255
00:18:20,210 --> 00:18:25,550
mortality rate ู„ุฃู† ู‡ุฐู‡ ุจุชู†ุฒู ููŠ ุฌู„ุจ ุงู„ู€ brain parenchyma ู‡ุฐุง
256
00:18:25,550 --> 00:18:30,830
ุงู„ุณุจุจ ู‚ุฏ ูŠูƒูˆู† ุถุนู ุงู„ุฌุฏุงุฑ ุจุณุจุจ ุชุฑุงูƒู… ุงู„ู€ amylodosis
257
00:18:30,830 --> 00:18:35,770
ุฃูˆ ุงู„ู€ hyaline ููŠ ู‚ู„ุจ ุงู„ุฌุฏุงุฑ ุชุจุน ุงู„ูˆุนุงุก ุฎู„ุงู‡ ูŠุถุนู
258
00:18:35,770 --> 00:18:40,050
cocaine abuse ุนู…ู„ู„ูŠ vasculitis ูˆ ุฎู„ุงู‡ ุงู„ุดุฑูŠุงู†
259
00:18:40,050 --> 00:18:45,190
ูŠู†ูุฌุฑ ู…ุฑูŠุถ ููŠ ุนู†ุฏู‡ ุฎู„ู„ ููŠ ุนู…ู„ูŠุฉ ุชุฌู„ุท ุงู„ุฏู… ู‡ุฐุง
260
00:18:45,190 --> 00:18:49,990
ุงู„ู…ุดูƒู„ุฉ ุฃู†ู‡ ุจูŠุนู…ู„ู„ูŠ sudden headache ุจูŠู‚ู„ู„ู„ูŠ ู…ุณุชูˆู‰
261
00:18:49,990 --> 00:18:54,490
ุงู„ูˆุนูŠ ุจูŠุนู…ู„ู„ูŠ ุชุดู†ุฌุงุช seizures nausea vomiting ูˆ
262
00:18:54,490 --> 00:18:58,280
increase blood pressure ุงู„ู…ุดูƒู„ุฉ ู‡ู†ุง double ุฃูˆู„
263
00:18:58,280 --> 00:19:03,200
ู…ุดูƒู„ุฉ ููŠ ุนู†ุฏูŠ ุงู†ูุฌุงุฑ ู†ุงุชุฌ ุนู†ู‡ accumulation of
264
00:19:03,200 --> 00:19:06,720
blood ูู‡ุฐุง ุจุฏุฃ ูŠุถุบุท ุนู„ู‰ ุงู„ู€ surrounding tissue
265
00:19:06,720 --> 00:19:10,280
ูุฃุฏู‰ ุฅู„ู‰ ุงู„ู€ ischemia ููŠ ุงู„ู€ surrounding tissue ูˆู…ู†ุน
266
00:19:10,280 --> 00:19:14,540
ู„ู„ุฏู… ููŠ ุงู„ู…ู†ุงุทู‚ ุงู„ุจุนูŠุฏุฉ ูŠุนู†ูŠ ู…ุซู„ู‹ุง ู„ูˆ ูƒุงู† ููŠ ุนู†ุฏูŠ
267
00:19:14,540 --> 00:19:18,900
200 CC ุงู„ู…ูุฑูˆุถ ูŠุตู„ ู„ู€ ุงู„ู…ู†ุทู‚ุฉ ุงู„ู€ occipital lobe ู…ุซู„ู‹ุง
268
00:19:18,900 --> 00:19:22,260
ูˆู…ุง ูˆุตู„ูˆุด ู„ุฃู†ู‡ ุตุงุฑ ุงู†ูุฌุงุฑ ููŠ ุงู„ุดุฑูŠุงู† ู‚ุจู„ ู…ุง ูŠุตู„
269
00:19:22,260 --> 00:19:25,900
ู‡ู†ุงูƒ ูุงู„ู…ู†ุทู‚ุฉ ุงู„ู„ูŠ ุงู†ูุฌุฑ ููŠู‡ุง ุบุฑู‚ุช ูˆ ุงู„ู…ู†ุทู‚ุฉ
270
00:19:25,900 --> 00:19:30,600
ุงู„ุจุนูŠุฏุฉ ุงู„ู„ูŠ ุงู„ู…ูุฑูˆุถ ูŠุตู„ู‡ุง ุนุทุดุช ู„ู‡ุฐุง ุงู„ุณุจุจ ู‡ูˆ ูŠู„ูŠ
271
00:19:30,600 --> 00:19:33,720
ุงู„ู€ double effect ูˆู…ู…ูƒู† ูŠุนู…ู„ู„ูŠ shifting ููŠ ุฏุงุฎู„
272
00:19:33,720 --> 00:19:37,020
ุงู„ุฏู…ุงุบ ูˆูŠุนู…ู„ู„ูŠ ู…ุดุงูƒู„ ู‡ุงูŠ ุนู†ุฏูŠ ุตูˆุฑ ุฃู†ุง ู„ุตุจุญ
273
00:19:37,020 --> 00:19:42,030
arachnoid hemorrhage ุนู†ุฏูŠ ุจุฑุถู‡ ุตูˆุฑ ุซุงู†ูŠุฉ ุงู„ู€
274
00:19:42,030 --> 00:19:44,690
intraventricular hemorrhage ููŠ ุนู†ุฏูŠ ู‡ูŠู‡ุง ุฏูŠ ุงู„ู€
275
00:19:44,690 --> 00:19:50,130
aneurysm ูƒูŠู ู…ูˆุฌูˆุฏุฉ ููŠ ุงู„ู†ุต ูˆ ูƒูŠู ุจุชู†ูุฌุฑุŒ ุงู„ุขู† ููŠ
276
00:19:50,130 --> 00:19:53,490
ุนู†ุฏูŠ general warning signs ู„ู€ stroke ุฃู†ู‡ ุจูŠุตูŠุฑ ููŠ
277
00:19:53,490 --> 00:19:58,370
ุนู†ุฏูŠ sudden weakness ูˆ sudden numbness sudden
278
00:19:58,370 --> 00:20:01,710
tingling sensation ููŠ one side of the body sudden
279
00:20:01,710 --> 00:20:05,690
dimness or loss of vision sudden inability to talk
280
00:20:05,690 --> 00:20:08,870
or trouble understanding the person's speech
281
00:20:08,870 --> 00:20:13,150
sudden headache without a cause unexplained
282
00:20:13,150 --> 00:20:16,730
dizziness unsteadiness or fog sudden decrease in
283
00:20:16,730 --> 00:20:20,030
consciousness ูƒู„ ู‡ุฐู‡ ุงู„ุฃุนุฑุงุถ ู…ู…ูƒู† ุชูˆุญูŠู„ูƒ ุฃู† ู‡ุฐุง
284
00:20:20,030 --> 00:20:24,390
ุงู„ุดุฎุต ู‚ุฏ ูŠูƒูˆู† ููŠ ุนู†ุฏู‡ ุฌู„ุทุฉ ุงู„ุขู† ููŠ ุฃู…ุฑูŠูƒุง ุทูˆุฑูˆุง
285
00:20:24,630 --> 00:20:28,410
scale ุจุณูŠุท ุฌุฏู‹ุง ุงุณู…ู‡ Cincinnati pre-hospital stroke
286
00:20:28,410 --> 00:20:32,630
ู„ุฃู†ู‡ ุฅุฐุง ุจุชุฐูƒุฑูˆุง ููŠ ุจุฏุงูŠุฉ ุงู„ู…ุญุงุถุฑุฉ ุฐูƒุฑุช time is
287
00:20:32,630 --> 00:20:37,210
brain ูŠุนู†ูŠ ูƒู„ ู…ุง ุฃู†ุง ุจูู‚ุฏ ุฏู‚ุงุฆู‚ ูƒู„ ู…ุง ุจูู‚ุฏ ุฎู„ุงูŠุง
288
00:20:37,210 --> 00:20:40,090
ูุงู„ู…ูุฑูˆุถ ุฃุฏุฑุจ ุงู„ู†ุงุณ ุงู„ู„ูŠ ุจุฏุฃุช ุชุดูˆู ุงู„ู…ุฑูŠุถ ููŠ ุฎู„ุงู„
289
00:20:40,090 --> 00:20:43,190
ุฏู‚ุงุฆู‚ ูƒูŠู ูŠุชุนุฑู ุฃู† ู‡ุฐุง ุงู„ู…ุฑูŠุถ ุนู†ุฏู‡ ุฌู„ุทุฉ ูˆูŠุจุฏุฃ
290
00:20:43,190 --> 00:20:47,190
ูŠุดุชุบู„ ู…ุนุงู‡ ู‡ูˆ ููŠ ุฏุงุฎู„ ุงู„ุฅุณุนุงู ูู‡ุฐุง ุจุชูƒูˆู† ู…ู† ุชู„ุงุชุฉ
291
00:20:47,190 --> 00:20:51,590
components ุฃูˆู„ ุญุงุฌุฉ ุงู„ู€ facial drop ุฃูˆ asymmetry
292
00:20:52,310 --> 00:20:55,510
ุจู†ุทู„ุจ ู…ู† ุงู„ู…ุฑูŠุถ ุฃู†ู‡ ูŠุถุญูƒ ุจู†ู„ุงู‚ูŠ ุชู…ูŠู„ ูˆ ุจุฑูˆุญ ุฌู‡ุฉ ุฃูƒุซุฑ ู…ู†
293
00:20:55,510 --> 00:20:59,910
ุฌู‡ุฉ ู‡ูŠ ู‡ุฐู‡ ุนู„ุงู…ุฉ ุจู†ุทู„ุจ ู…ู† ุงู„ู…ุฑูŠุถ ูŠุฑูุน ูŠุฏูŠู‡ ุฅุฐุง ูƒุงู†
294
00:20:59,910 --> 00:21:03,210
ุงู„ู…ู†ุทู‚ุฉ ุงู„ู„ูŠ ููŠู‡ุง ุงู„ุถุนู ุฃูˆ ุงู„ุฌู„ุทุฉ ู‡ูˆ ุงู„ู…ุฑูŠุถ ู…ุบู…ุถ
295
00:21:03,210 --> 00:21:08,370
ุนูŠู†ูŠู‡ ุฑุงุญ ุชู„ุงู‚ูŠู‡ุง ุชุญุช ุงูŠู‡ ุจู†ุทู„ุจ ู…ู† ุงู„ู…ุฑูŠุถ ูŠุญูƒูŠ ุฌู…ู„ุฉ
296
00:21:08,370 --> 00:21:13,150
ู…ุนูŠู†ุฉ ุฃูˆ ูŠู‚ูˆู„ ุจุณู… ุงู„ู„ู‡ ุฃูˆ ูŠู‚ุฑุฃ ุตูˆุฑุฉ ู…ุซู„ู‹ุง ุงู„ูุงุชุญุฉ
297
00:21:13,150 --> 00:21:16,530
ูุจู†ู„ุงู‚ูŠ ุงู„ู…ุฑูŠุถ ุจุฏุฃ ูŠุชู„ุนุซู… ุจุงู„ูƒู„ุงู… ูู‡ุฐู‡ ุจุฑุถู‡ ุจุฏูŠู†ุง
298
00:21:16,530 --> 00:21:19,880
ุนู„ุงู…ุงุช ููŠ ู‡ุฐู‡ ุงู„ู„ุญุธุฉ ุงู„ู…ูุฑูˆุถ ุงู„ู„ูŠ ููŠ ุงู„ุฅุณุนุงู ููŠ ุงู„ู€
299
00:21:19,880 --> 00:21:23,040
paramedics ูŠุจู„ุบูˆุง ููŠ ุฃู‚ุณุงู… ุงู„ุทูˆุงุฑุฆ ุฃู†ู‡ ุฃู†ุง ููŠ ุนู†ุฏูŠ
300
00:21:23,040 --> 00:21:25,820
ู…ุฑูŠุถ suspected of stroke ูˆูŠู† ุงู„ู„ูŠ ูŠุจู‚ูˆุง ุงู„ูƒุงุฏุฑ
301
00:21:25,820 --> 00:21:29,320
ูŠูุนู„ูˆุง ูุฑูŠู‚ ุงู„ู€ stroke ููŠ ุงู„ู…ุณุชุดูู‰ ุทุจ ุฅูŠุด ุจุฏู†ุง
302
00:21:29,320 --> 00:21:32,360
ู†ุนู…ู„ู‡ ุฃูˆู„ ู…ุง ูŠุตู„ุŸ ููŠ ุฃูˆู„ ุนุดุฑ ุฏู‚ุงุฆู‚ ุจุฏู†ุง ู†ู‚ูŠู… ุงู„ู€
303
00:21:32,360 --> 00:21:36,830
ABC ุงู„ู„ูŠ ู‡ุชุดูŠุฑ ู„ู€ ุงู„ู€ blood ุงู„ู€ ABC ุงู„ู„ูŠ ู‡ูˆ ุงู„ู„ูŠ ุงู„ู€
304
00:21:36,830 --> 00:21:39,630
airway ูˆ ุงู„ู€ breathing ูˆ ุงู„ู€ circulation ูˆ ุงู„ู€ vital
305
00:21:39,630 --> 00:21:43,290
signs ุจุฏู†ุง ู†ุดูˆู ุงู„ู€ ABG ุฅุฐุง ููŠ ุนู†ุฏู‡ ู†ู‚ุต ุงู„ู€ oxygen
306
00:21:43,290 --> 00:21:50,090
ุจุฏู†ุง ู†ุนู…ู„ู‡ ู…ุซู„ู‹ุง ู†ุนุทูŠู‡ oxygen by nasal cannula ู„ุฃู†ู‡
307
00:21:50,090 --> 00:21:53,470
ุฐูƒุฑู†ุง ุฃู‡ู… ุงู„ุฃุณุจุงุจ ุชุจุน ุงู„ุฌู„ุทุฉ ู‡ูˆ ู†ู‚ุต ุงู„ู€ oxygen ูˆ
308
00:21:53,470 --> 00:21:57,550
blood supply ูุฃู‚ู„ ุดูŠุก ุฃู†ู‡ ู†ุฏูŠู„ู‡ oxygen ุนุดุงู† ู†ุญุงูˆู„
309
00:21:57,550 --> 00:22:02,410
ู†ู†ู‚ุฐ ุทุจุนู‹ุง ููŠ ุฏุฑุงุณุงุช ุจุชู†ููŠ ู…ูุนูˆู„ ุงู„ู€ oxygen ุงู„ู€
310
00:22:02,410 --> 00:22:06,500
hundred percent concentration ูˆู„ูƒู† ู„ู…ุง ุฒุงู„ ู‡ุฐุง
311
00:22:06,500 --> 00:22:10,660
ุงู„ู…ู…ุงุฑุณุฉ ุดุบุงู„ุฉ ููŠ ู…ุนุธู… ุงู„ู…ุณุชุดููŠุงุช ุจุฏู†ุง ู†ุฌูŠุจ IV
312
00:22:10,660 --> 00:22:15,180
line access ุงู„ู„ูŠ ู†ุงุฎุฏ ู…ู†ู‡ ุนูŠู†ุงุช ูˆูุญูˆุตุงุช ุงู„ุฏู… ุจุฏู†ุง
313
00:22:15,180 --> 00:22:18,660
ู†ุนู…ู„ู‡ ุชุฎุทูŠุท ู„ู„ู‚ู„ุจ ู†ุดูˆู ุงู„ู€ rhythm ูˆู†ุดูˆู ุฅุฐุง ูƒุงู† ููŠ
314
00:22:18,660 --> 00:22:23,240
ุนู†ุฏูŠ ุฃูŠ ู…ุดูƒู„ุฉ ููŠ ุงู„ู‚ู„ุจ AF ู…ู…ูƒู† ุชูƒูˆู† ู‡ูŠ ุณุจุจ ุงู„ุฌู„ุทุฉ
315
00:22:23,240 --> 00:22:28,190
ู†ุดูˆู ุงู„ุณูƒุฑ ู…ู…ูƒู† ูŠูƒูˆู† ููŠ ุนู†ุฏู‡ hypoglycemia ุจุฏู†ุง ู†ู†ุงุฏูŠ
316
00:22:28,190 --> 00:22:31,490
ูุฑูŠู‚ ุงู„ู€ stroke ุงู„ู„ูŠ ู‡ูˆ ุจุชูƒูˆู† ู…ู† ุงู„ู€ acute
317
00:22:31,490 --> 00:22:34,770
neurologist ูˆ ุงู„ู€ radiologist ูˆ ุงู„ู€ CT stuff ุจุฏู†ุง
318
00:22:34,770 --> 00:22:39,130
ู†ุนู…ู„ assessment ู„ู„ู…ุฑูŠุถ ูˆ always reassess ู„ุฃู†
319
00:22:39,130 --> 00:22:44,340
ุงู„ู…ุฑูŠุถ ุจูŠุชุฏู‡ูˆุฑ ุจุณุฑุนุฉ ููŠ ุฃูˆู„ 25 ุฏู‚ูŠู‚ุฉ ู…ู† ูˆุตูˆู„ ุงู„ู…ุฑูŠุถ
320
00:22:44,340 --> 00:22:48,540
ุงู„ู…ูุฑูˆุถ ุฃู†ู‡ ุงู„ู…ุฑูŠุถ ุจุฏุฃู†ุง ู†ุงุฎุฏ better history ุนู†ู‡
321
00:22:48,540 --> 00:22:52,720
ุฅูŠุด ุงู„ู„ูŠ ุตุงุฑ ู…ุนู‡ ุจุฏู†ุง ู†ุงุฎุฏ ุงู„ู€ symptoms ุงู…ุชู‰ ุธู‡ุฑุช
322
00:22:52,720 --> 00:22:56,240
ุฅุฐุง ูƒุงู† ุฃู‚ู„ ู…ู† ุชู„ุงุช ุณุงุนุงุช ุนุดุงู† ู…ู…ูƒู† ู‡ุฐุง ุงู„ู…ุฑูŠุถ ูŠูƒูˆู†
323
00:22:56,240 --> 00:23:00,560
candidate ู…ุฑุดุญ ู„ุฅู†ู‡ ูŠุงุฎุฏ ุงู„ู€ fibrinolytic agents ุงู„ู„ูŠ
324
00:23:00,560 --> 00:23:05,920
ูŠู†ู‚ุฐ ุญูŠุงุชู‡ ุจุฏู†ุง ู†ุนู…ู„ ูุญูˆุตุงุช ุนุตุจูŠุฉ ุฃูƒุซุฑ ูˆุฃูƒุซุฑ ู†ุงุฎุฏ
325
00:23:05,920 --> 00:23:09,180
ุงู„ู€ Glasgow ู†ุงุฎุฏ ุงู„ู€ deficit severity ุถุฑูˆุฑูŠ ุฃู†ู‡
326
00:23:09,180 --> 00:23:13,520
ู†ุนู…ู„ู‡ ุงู„ู€ CT scan ุงู„ู…ูุฑูˆุถ ุฃู† ุงู„ู€ CT ูƒุงู†ุช ุฎู„ุงู„ 45
327
00:23:13,520 --> 00:23:18,620
ุฏู‚ูŠู‚ุฉ ุงู†ู‚ุฑุช ูˆุทู„ุนุช ุชู‚ุฑูŠุฑ ุชุจุนู‡ุง ุจุฑุถู‡ ุฅุฐุง ูƒุงู† ุดุงูƒูŠูŠู†
328
00:23:18,620 --> 00:23:23,160
ุฃู† ุงู„ู…ุฑูŠุถ ููŠ ุนู†ุฏู‡ ุฅุตุงุจุฉ ุฃูˆ ุถุฑุจุฉ ุจู†ุนู…ู„ู‡ lateral x
329
00:23:23,160 --> 00:23:27,540
-ray ู„ู€ ุงู„ู€ neck ุนุดุงู† ู†ุณุชุจุนุฏ ูˆุฌูˆุฏ ุถุฑุจุฉ ุฃูˆ ูƒุณุฑ ููŠ
330
00:23:27,540 --> 00:23:32,860
ุงู„ุฑู‚ุจุฉ ุงู„ุขู† ู„ูŠุด ุถุฑูˆุฑูŠ ู†ุนู…ู„ ุงู„ู€ CT ููŠ ุฃูˆู„ ุญุงุฌุฉ ู†ุนู…ู„ู‡ุง
331
00:23:32,860 --> 00:23:38,260
ุงู„ู‡ุฏู ุงู„ุฃุณุงุณูŠ ุชุจุนู‡ุง ุดูŠุก ูˆุงุญุฏ ู…ุด ุชุดุฎูŠุต ischemic
332
00:23:38,260 --> 00:23:41,480
stroke ูˆู„ูƒู† ุงุณุชุจุนุงุฏ hemorrhagic stroke ุงุณุชุจุนุงุฏ
333
00:23:41,480 --> 00:23:43,920
hemorrhagic stroke ู„ุฃู† ุฅุฐุง ูƒุงู† ุงุณุชุจุนุงุฏ hemorrhagic
334
00:23:43,920 --> 00:23:48,180
stroke ุฃูˆ ุงุณุชุจุนุงุฏ ู†ูŠูˆ ุจู„ุงุฒู… ุฃูˆ abscess ุณุงุนุชู‡ุง ุจูŠุธู„
335
00:23:48,180 --> 00:23:51,180
ุนู†ุฏูŠ ุงู„ู€ 80% ุงู„ู„ูŠ ู‡ูˆ ุงู„ู€ ischemic ูุจูŠุตูŠุฑ ู‡ุฐุง ุงู„ุดุฎุต
336
00:23:51,180 --> 00:23:55,500
ู…ุคู‡ู„ ุฃู† ุฃู†ุง ุฃุฏูŠู„ู‡ fibrinolytic agent ุฃุฏูˆุจู„ู‡
337
00:23:55,500 --> 00:24:03,320
ุงู„ุฌู„ุทุฉ ุงู„ุขู† ูƒู€ ischemic stroke ุนููˆู‹ุง ู…ุด ุฑุงุญ ุชุธู‡ุฑ
338
00:24:03,320 --> 00:24:07,580
ุงู„ู†ุชุงุฆุฌ ุชุจุนู‡ุง ุฅู„ุง ุบูŠุฑ ุจุนุฏ ูŠูˆู… ุฃูˆ ูŠูˆู…ูŠู† ุชุธู‡ุฑ ู„ูŠ ููŠู‡
339
00:24:07,580 --> 00:24:13,810
ischemia ูˆู„ูƒู† hemorrhage ุจุธู‡ุฑ ููŠ ุฎู„ุงู„ ุฃูˆู„ ุนุดุฑ ุฏู‚ูŠู‚ุฉ
340
00:24:13,810 --> 00:24:17,070
ุฃูˆ ุงุชู†ูŠู† ุฏู‚ูŠู‚ุฉ ุจุธู‡ุฑ ุทุจ ุฅูŠุด ูุญูˆุตุงุช ุซุงู†ูŠุฉ ู…ู…ูƒู† ุฃุนู…ู„ู‡ุง
341
00:24:17,070 --> 00:24:20,530
carotid duplex scanning ุนุดุงู† ุฃุดูˆู ุฅุฐุง ูƒุงู† ุงู„ู€
342
00:24:20,530 --> 00:24:25,610
carotid artery ููŠ ุนู†ุฏู‡ atheroma ูู…ู…ูƒู† ู†ุฑุดุญ ู‡ุฐุง
343
00:24:25,610 --> 00:24:30,070
ุงู„ู…ุฑูŠุถ ูƒูˆู‚ุงุฆูŠ ู†ุนู…ู„ู‡ endarterectomy ุฅุฒุงู„ุฉ ู‡ุฐุง ุงู„ู€
344
00:24:30,070 --> 00:24:32,710
atheroma ู…ู† ุงู„ู€ carotid artery ุจุฑุถู‡ ุงู„ู€
345
00:24:32,710 --> 00:24:36,010
echocardiography ู†ุดูˆู ุฅุฐุง ูƒุงู† ููŠู‡ ุงู„ู€ imbalance ุฌุงูŠ
346
00:24:36,010 --> 00:24:39,520
ู…ู† ุงู„ู€ heart ุจุฑุถู‡ ุงู„ู€ MRI ุจุงู„ู†ุงุณ ุงู„ู„ูŠ ุนู†ุฏู‡ู…
347
00:24:39,520 --> 00:24:43,320
cerebellar ุฃูˆ ุงู„ู€ corner in fact ู„ุฃู† ู‡ุฐู‡ ุงู„ู…ู†ุงุทู‚ ุฏู‚ูŠู‚ุฉ
348
00:24:43,320 --> 00:24:46,980
ูˆู„ุง ุชุธู‡ุฑ ููŠ ุงู„ู€ CT scan ุจุฑุถู‡ ุจุฏู†ุง ู†ุดูˆู ุฅุฐุง
349
00:24:46,980 --> 00:24:49,400
ุงู„ู…ุฑูŠุถ ููŠ ุนู†ุฏู‡ ู…ุดุงูƒู„ ููŠ ุงู„ู‚ู„ุจ ู†ุนู…ู„ู‡ Holter
350
00:24:49,400 --> 00:24:54,540
monitoring ู„ุฃู†
351
00:24:54,540 --> 00:24:58,140
ู„ู…ุง ุจู†ุญูƒูŠ ุนู„ู‰ ุงู„ู€ management ุชุจุน ุงู„ู€ stroke ุทุจุนู‹ุง
352
00:24:58,140 --> 00:25:04,560
ุจุชุถู…ู† ู„ู€ ุฃุฑุจุน ุฃุฑุจุน ู…ุฑุงุญู„ ุฃูˆ ุฃุฑุจุน approaches ู…ู…ูƒู†
353
00:25:04,560 --> 00:25:07,560
ูŠุดุชุบู„ูˆุง ู…ุน ุจุนุถ ุฃูˆ ุจุดูƒู„ ู…ุชุชุงู„ูŠ ุฃูˆู„ ุญุงุฌุฉ ุงู„ู€
354
00:25:07,560 --> 00:25:10,760
preventive ู‡ุฐู‡ ู‚ุจู„ ูˆุจุนุฏ ุงู„ุฌู„ุทุฉ ุนุดุงู† ู†ู…ู†ุน ุญุฏูˆุซ
355
00:25:10,760 --> 00:25:14,940
ุฌู„ุทุฉ ูˆู„ูˆ ุตุงุฑุช ู†ู…ู†ุน ุชูƒุฑุงุฑ ุงู„ุฌู„ุทุฉ ุจุฑุถู‡ emergency
356
00:25:14,940 --> 00:25:18,900
drugs and supporting care ู‡ุฐู‡ ุจุฏู†ุง ู†ู‚ู„ู„ ุงู„ุชุฃุซูŠุฑ
357
00:25:18,900 --> 00:25:22,580
ุงู„ุณู„ุจูŠ ุชุจุน ุงู„ุฌู„ุทุฉ ุนู„ู‰ ุงู„ุฏู…ุงุบ ูˆู†ูˆู‚ู ุนู†ุฏ ุงู„ุญุฏ ู‡ุฐุง
358
00:25:22,580 --> 00:25:27,560
ุงู„ู€ neuroprotective agents ู‡ุฐู‡ ุชุณุชุฎุฏู… ูƒุญู…ุงูŠุฉ ู„ุจุงู‚ูŠ
359
00:25:27,560 --> 00:25:34,270
ุงู„ุฎู„ุงูŠุง ู…ู† ุงู„ุชุฃุซุฑ ุจุงู„ู€ metabolic products ุงู„ู„ูŠ
360
00:25:34,270 --> 00:25:37,110
ู‡ูŠ ู…ู…ูƒู† ุชุถุฑู‡ุง ูˆุจุฑุถู‡ ุงู„ู€ rehabilitative management
361
00:25:37,110 --> 00:25:47,830
ู…ุง ุจุนุฏ ุงู„ุญุงู„ุฉ ุงู„ู€ acute ุงู„ู„ูŠ ุจูŠุตูŠุฑ ุนู†ุฏ ุงู„ู…ุฑูŠุถ ุงู„ุขู†
362
00:25:47,830 --> 00:25:50,750
ููŠ ุงู„ู€ emergency ุถุฑูˆุฑูŠ ุงู„ู€ airway ูˆ ุงู„ู€ breathing
363
00:25:50,750 --> 00:25:55,130
ุถุฑูˆุฑูŠ ุฃู† ู†ุดูŠูƒ ุฃู† ูˆุถุน ุงู„ู…ุฑูŠุถ ุงู„ู€ Glasgow coma scale
364
00:25:55,130 --> 00:25:59,710
ู…ุง ูŠู‚ู„ุด ุนู† ุชู…ุงู†ูŠุฉ ุงู„ู€ blood pressure ุงู„ุขู† ููŠ ู…ุฑุถู‰
365
00:25:59,710 --> 00:26:03,730
ุจูŠูƒูˆู† ุนู†ุฏู‡ hemorrhagic CVA ุทุจ ุงุญู†ุง ู„ุฌูŠู†ุง ุตุงุฑ ุนู†ุฏู‡
366
00:26:03,730 --> 00:26:06,950
ุงู„ู€ hemorrhagic ุจุณุจุจ ุงู†ูุฌุงุฑ ุดุฑูŠุงู† ููŠ ุงู„ุฏู…ุงุบ ูˆูƒุงู†
367
00:26:06,950 --> 00:26:11,930
ุงู„ุณุจุจ ุฃู†ู‡ ุถุบุทู‡ ู„ุฌูŠู†ุง ู…ุซู„ู‹ุง ู…ุงุฆุชูŠู† ูˆุฎู…ุณูŠู† ุนู„ู‰ .. ุนู„ู‰
368
00:26:11,930 --> 00:26:17,090
ู…ูŠุฉ ูˆุฃุฑุจุนูŠู† ู…ุซู„ู‹ุง ุถุบุท ุนุงู„ูŠ ุฌุฏู‹ุง ุทุจ ุงุญู†ุง ุงู„ู…ูุฑูˆุถ ุฃู†ู‡
369
00:26:17,090 --> 00:26:20,210
ู†ุฑุฌุน ุงู„ุถุบุท ู„ู„ูˆุถุน ุงู„ุทุจูŠุนูŠ ุงู„ูˆุถุน ุงู„ุทุจูŠุนูŠ ู…ูŠุฉ ูˆุนุดุฑูŠู†
370
00:26:20,210 --> 00:26:23,910
ุนู„ู‰ ุซู…ุงู†ูŠู† ุจุฏู†ุง ู†ุงุฎุฏ ููŠ ู‡ุฐุง ุงู„ุงุนุชุจุงุฑ ุนุฏุฉ ุดุบู„ุงุช ุฃูˆู„
371
00:26:23,910 --> 00:26:28,420
ุดูŠุก ู„ู…ุง ุงู„ู…ุฑูŠุถ ูŠูƒูˆู† ุนู…ุฑู‡ ุณุชูŠู† ุฃูˆ ุฎู…ุณ ูˆ ุณุชูŠู† ุงู„ูˆุถุน
372
00:26:28,420 --> 00:26:31,560
ุงู„ุทุจูŠุนูŠ ู„ู„ุถุบุท ู…ุด ู…ูŠุฉ ูˆุนุดุฑูŠู† ุนู„ู‰ ุซู…ุงู†ูŠู† ุงู„ูˆุถุน
373
00:26:31,560 --> 00:26:35,640
ุงู„ุทุจูŠุนูŠ ู„ู‡ุฐุง ุงู„ุดุฎุต ุจู‡ุฐุง ุงู„ุณู† ู‚ุฏ ูŠูƒูˆู† ู…ูŠุฉ ูˆุซู„ุงุซูŠู†
374
00:26:35,640 --> 00:26:38,340
ุนู„ู‰ ุฎู…ุณ ูˆุซู…ุงู†ูŠู† ู‚ุฏ ูŠูƒูˆู† ู…ูŠุฉ ูˆุฃุฑุจุนูŠู† ุนู„ู‰ ุชุณุนูŠู†
375
00:26:38,340 --> 00:26:43,460
ู‡ุฐุง ุนุงุฏูŠ ู…ู‚ุจูˆู„ ุจู‡ุฐุง ุงู„ุณู† ูˆุญุชู‰ ู„ูˆ ูƒุงู† ุงู„ูˆุถุน ุงู„ุทุจูŠุนูŠ
376
00:26:43,460 --> 00:26:48,280
ู„ู‡ูŠุฆู„ู‡ ุฃู†ู‡ ุดุงุจุดุงุจ ููŠ ุงู„ู…ู…ู†ูˆุน ู…ู†ุนุง ุจุญูŠุซ ุฃู† ุงุญู†ุง ู†ู‚ู„ู„
377
00:26:48,280 --> 00:26:54,140
ุงู„ุถุบุท ุจุดูƒู„ ู…ุชุณุงุฑุน ู„ุฃู†ู‡ ู„ูˆ ู†ุฒู„ู†ุง ุงู„ุถุบุท ู…ู† 250 ู„ู€ 120
378
00:26:54,140 --> 00:26:59,100
ุฃูˆ ู„ู€ 130 ุงุญู†ุง ุฑุงุญ ู†ุณุจุจ ู„ู‡ ischemic changes ูุฑุงุญ ูŠุตูŠุฑ
379
00:26:59,100 --> 00:27:02,120
ุนู†ุฏู‡ ุจุงู„ุฅุถุงูุฉ ู„ู€ hemorrhagic cva ุฑุงุญ ูŠุตูŠุฑ ููŠ ุนู†ุฏู‡
380
00:27:02,120 --> 00:27:07,220
ischemic changes ูู„ุงุฒู… ุงุญู†ุง ู†ู†ูˆุท ุงู„ุถุบุท ุจุงู„ุชุฏุฑูŠุฌ ูˆ
381
00:27:07,220 --> 00:27:10,580
ู†ุงุฎุฐ ููŠ ุงู„ุงุนุชุจุงุฑ ุฅุฐุง ูƒุงู† ุงู„ู…ุฑูŠุถ ููŠ ุนู†ุฏู‡ ุฃู…ุฑุงุถ
382
00:27:10,580 --> 00:27:16,230
ุฃุฎุฑู‰ ุทุจ ุงู…ุชู‰ ุงุญู†ุง ุจุฏู†ุง ู†ู†ูˆุท ุงู„ุถุบุทุŸ ูˆู†ูˆุทูŠู‡ ุจุดูƒู„
383
00:27:16,230 --> 00:27:20,890
ุฃุณุฑุน ุฅุฐุง ูƒุงู† ุงู„ู€ .. ุงู„ู€ .. ุงู„ุถุบุท ุนุงู„ูŠ ุฌุฏุง ุฃูƒุซุฑ ู…ู†
384
00:27:20,890 --> 00:27:24,450
220 ูˆ ุงู„ู€ diastolic ุฃูƒุซุฑ ู…ู† 120 ุฅุฐุง ูƒุงู† ููŠ
385
00:27:24,450 --> 00:27:27,070
ู†ุฒูŠู ุฏู…ุงุบูŠ ุชุญูˆู„ูŠ ูˆุฃู†ุง ุฎุงุฆู ู…ู†ู‡ุง ุฃู†ู‡
386
00:27:27,070 --> 00:27:31,960
ูŠุชุญูˆู„ ู„ู…ุฑูŠุถ ู…ู† ู…ุฑูŠุถ ูƒุงู† ููŠู‡ ุนู†ุฏู‡ ischemic ูˆุฌุงูŠูŠู†
387
00:27:31,960 --> 00:27:36,360
ุจุฌู„ุทุฉ ูˆู…ุน ุงุฑุชูุงุน ุงู„ุถุบุท ู…ู…ูƒู† ูŠู†ูุฌุฑ ุดุฑูŠุงู† ุฃูˆ ูŠุชุญูˆู„
388
00:27:36,360 --> 00:27:39,520
ู„ู†ูŽุฒูŠู ุงู„ู…ุฑูŠุถ ููŠู‡ ุนู†ุฏู‡ cardiac ischemia ุงู„ู…ุฑูŠุถ ููŠู‡
389
00:27:39,520 --> 00:27:43,180
ุนู†ุฏู‡ aortic dissection ูˆู…ู…ูƒู† ู„ูˆ ุชุฑูƒู†ุง ุงู„ุดุฎุต ุงู„ุถุบุท
390
00:27:43,180 --> 00:27:47,420
ุนุงู„ูŠ ุฌุฏุง ู…ู…ูƒู† ู‡ุฐุง ุงู„ุดุฑูŠุงู† ุงู„ุฃูˆุฑุทูŠ ูŠุตูŠุฑ ููŠู‡ ุชู…ุฒู‚
391
00:27:47,420 --> 00:27:51,220
ุฃูƒุซุฑ ูˆุงู„ู…ุฑูŠุถ ูŠุตูŠุฑ ูŠุฎุด ููŠ ู…ุดูƒู„ุฉ ุซุงู†ูŠุฉ ุฃูƒุซุฑ ู„ูˆ
392
00:27:51,220 --> 00:27:54,920
ุงู„ู…ุฑูŠุถ ููŠู‡ ุนู†ุฏู‡ ischemia ููŠ ุงู„ู€ kidneys ู‡ุฐุง ุจุฑุถู‡
393
00:27:54,920 --> 00:28:00,420
ู„ุงุฒู… ู†ู†ูˆุท ุงู„ุถุบุท ุงู„ู…ุฑูŠุถ ู„ุงุฒู… ู†ุฏูŠู„ู‡ antibiotics ู„ูŠุด
394
00:28:00,420 --> 00:28:03,040
ุจู†ุฏูŠู‡ ุงู„ู€ antibioticsุŸ ุนุดุงู† ู†ู‚ู„ู„ ุงู„ุญุฑุงุฑุฉ ููŠ ุงู„ุฌุณู… ุทุจ
395
00:28:03,040 --> 00:28:06,440
ู„ูŠุด ุจู†ู‚ู„ู„ ุญุฑุงุฑุฉ ุงู„ุฌุณู…ุŸ ุนุดุงู† ู†ู‚ู„ู„ ุงู„ู€ metabolic needs
396
00:28:06,440 --> 00:28:11,000
ู„ุฃู† ุงู„ุฏู…ุงุบ ู…ุง ููŠุด ูƒู…ูŠุฉ ุฃูƒุณุฌูŠู† ูƒุงููŠุฉ ูู„ุงุฒู… ู†ู‚ู„ู„ ูƒู…ูŠุฉ
397
00:28:11,000 --> 00:28:14,800
ุงู„ุฃูƒุณุฌูŠู† ุงู„ู…ุทู„ูˆุจุฉ ููŠ ุงู„ุฌุณู… ูุจู†ุนู…ู„ ู†ุฏูŠู„ู‡
398
00:28:14,800 --> 00:28:18,020
antibiotics ุจุฑุถู‡ ุจู†ุฏูŠ seizure control ุนุดุงู† ู†ู‚ู„ู„
399
00:28:18,020 --> 00:28:19,280
ุงู„ุญุฑูƒุฉ ุชุจุน ุงู„ู…ุฑูŠุถ
400
00:28:22,210 --> 00:28:25,530
ุงู„ู€ neuroprotective agents ู‡ู†ุง ููŠู‡ ุฏุฑุงุณุงุช ูƒุซูŠุฑุฉ
401
00:28:25,530 --> 00:28:30,310
ุนู…ู„ุช ุนู„ู‰ ุนุดุฑุงุช ุงู„ุฃู†ูˆุงุน ูˆู„ูƒู† ู„ู„ุฃุณู ูŠุนู†ูŠ ู‚ู„ูŠู„ ู…ู†ู‡ุง
402
00:28:30,310 --> 00:28:34,790
ุงู„ู„ูŠ ุฃุธู‡ุฑ evidence ุฃู†ู‡ ูุนู„ุง ุจูŠุณูˆูŠ ุชุบูŠูŠุฑ ูˆู„ูƒู† ููŠู‡
403
00:28:34,790 --> 00:28:39,010
ุงุฏุนุงุก case by case ูŠุนู†ูŠ case studies case series
404
00:28:39,010 --> 00:28:44,230
ุฃู†ู‡ ุงู„ู…ุฑุถู‰ ุชุญุณู† ู„ู…ุง ู†ุฏูŠู‡ู… ู…ุซู„ุง Notreville ู„ู…ุง ู†ุฏูŠู‡
405
00:28:44,230 --> 00:28:49,440
ู„ู‡ู… Campton ู„ู…ุง ู†ุฏูŠู‡ ู„ู‡ู… Oxibrol ุจุนุถ ุงู„ุฃุดูŠุงุก ู‡ุฐู‡
406
00:28:49,440 --> 00:28:53,960
ุงู„ู…ู†ุดุทุฉ ุงู„ุฏูˆุงุก ุงู„ูˆุญูŠุฏ ุจุตุฏู‚ ุงู„ู„ูŠ ู‡ูˆ ุนู„ูŠู‡ ุฏุฑุงุณุงุช
407
00:28:53,960 --> 00:28:58,240
ูˆูŠู„ู‡ some evidence ุฃู†ู‡ ุจููŠุฏ ูˆููŠ ุฃูˆู„ ู…ุฑุงุญู„ ูู‡ูˆ ุงู„ู€
408
00:28:58,240 --> 00:29:02,420
cerebralazine ูˆุจุงู„ุฐุงุช ููŠ ุญุงู„ุงุช ุงู„ุฌู„ุทุงุช ุงู„ุงู†ุณุฏุงุฏูŠุฉ
409
00:29:02,420 --> 00:29:08,400
ู„ุฃู† ุงู„ู€ prognosis ู„ู„ู…ุฑุถู‰ ุงู„ู„ูŠ ุนู†ุฏู‡ู… ischemic stroke
410
00:29:08,400 --> 00:29:12,700
ูˆู†ุฏูŠู†ุงู„ู‡ู… fibrolytic agent ุฃูˆ TBA ุฃูˆ tissue plasma
411
00:29:12,700 --> 00:29:17,270
gene activator ุงู„ู„ูŠ ุฌูŠู†ุง ุงู„ู…ุฑุถู‰ ุงู„ูˆุถุน ุงู„ุนุตุจูŠ ุชุจุนู‡ู…
412
00:29:17,270 --> 00:29:20,070
ุซู„ุงุซูŠู† ููŠ ุงู„ู…ุฆุฉ ุจูŠุฑุฌุนู‡ normal ุฃูˆ minimal
413
00:29:20,070 --> 00:29:23,070
neurological deficit ุซู„ุงุซูŠู† ููŠ ุงู„ู…ุฆุฉ ุจูŠุธู„ ููŠ ุนู†ุฏู‡ู…
414
00:29:23,070 --> 00:29:26,110
mild to moderate ุนุดุฑูŠู† ููŠ ุงู„ู…ุฆุฉ ุจูŠุธู„ ููŠ ุนู†ุฏู‡ู…
415
00:29:26,110 --> 00:29:29,010
moderate to severe ูˆุนุดุฑูŠู† ููŠ ุงู„ู…ุฆุฉ ุจุชูˆููˆุง
416
00:29:29,010 --> 00:29:32,350
ูุงู„ุนู…ู„ูŠุฉ ู…ุด ุณู‡ู„ุฉ ุงู„ู…ุฑูŠุถ ู„ุงุฒู… ูŠู…ุถูŠ ุนู„ู‰ consent ุฃู†
417
00:29:32,350 --> 00:29:36,230
ู‡ูˆ ูŠุชู‚ุจู„ ุงู„ู€ risk ููŠ ู‡ุฐู‡ ุงู„ุนู…ู„ูŠุฉ functional
418
00:29:36,230 --> 00:29:41,030
speaking ุจุนุฏ ุฅุนุทุงุก ู‡ุฐุง ุงู„ุฏูˆุงุก 50% ู…ู†ู‡ู… ุจูŠุตูŠุฑ ููŠ
419
00:29:41,030 --> 00:29:44,870
ุนู†ุฏู‡ู… complete or almost complete independence 15%
420
00:29:44,870 --> 00:29:48,530
ุจูŠุจู‚ูˆุง ููŠ ุนู†ุฏู‡ู… some moderate dependence 15%
421
00:29:48,530 --> 00:29:54,050
complete dependence on others 20% mortality ู†ุญูƒูŠ
422
00:29:54,050 --> 00:29:59,130
ุนู„ู‰ ุงู„ุดู‚ ุงู„ุฃุฎูŠุฑ ุงู„ุขู† ูˆู‡ูˆ ุงู„ุฌู„ุทุงุช ุงู„ุชุฃู‡ูŠู„ ุนู…ู„ูŠุฉ
423
00:29:59,130 --> 00:30:02,610
ุงู„ุชุฃู‡ูŠู„ ุนู…ู„ูŠุฉ ุงู„ุชุฃู‡ูŠู„ ู‡ุฐู‡ ุฑุงุญ ู†ุชุญุฏุซ ุนู„ูŠู‡ุง ุฅู† ุดุงุก
424
00:30:02,610 --> 00:30:06,890
ุงู„ู„ู‡ ููŠ ุงู„ุดู‚ ุงู„ุซุงู†ูŠ ู„ุฃู†ู‡ ุงู„ุญุฌู… ุชุจุน ุงู„ู…ุญุงุถุฑุฉ ุฐุงุช
425
00:30:07,160 --> 00:30:09,460
ูู‡ูˆ ุฃู†ุง ุฑุงุญ ุฃุชูˆู‚ู ุงู„ุขู† ูˆุฅู† ุดุงุก ุงู„ู„ู‡ ู†ูƒู…ู„ ููŠ ุงู„ุดู‚
426
00:30:09,460 --> 00:30:11,900
ุงู„ุซุงู†ูŠุŒ ูŠุนุทูŠูƒู… ุงู„ุนููˆ ูˆุฃุชู…ู†ู‰ ู„ูƒู… ุงู„ุณุนุงุฏุฉ