Pridinol Mesilate
Pridinol mesilate is a centrally acting muscle relaxant that is used in the symptomatic treatment of muscle spasm. It is also used as the hydrochloride salt for its antimuscarinic activity in the management of parkinsonism.
1.5-3 mg pridinol 3 times daily. The duration of administration is decided by the treating doctor. The administration is independent of meals, with the onset of the effect being faster when taken before meals. Tablets should be taken with sufficient fluid (e.g. 1 glass of water) and not chewed.
Prindol potentiates the effect of anticholinergics such as atropine.
Hypersensitivity to the active substance or to any of the excipients, glaucoma, prostate hypertrophy, syndrome with urinary retention, gastrointestinal obstructions, arrhythmia, first trimester of pregnancy.
The following adverse effects may occur, particularly during concomitant administration with other anticholinergic medicinal products: dry mouth, thirst, transient visual disorder (mydriasis, difficulties with accommodation, photosensitivity, slight increase in intraocular pressure), redness and dryness of the skin, bradycardia followed by tachycardia, micturition disorders, constipation and, very rarely, vomiting, dizziness and unsteady gait. Other side effects occur in fewer than 1 in 100 patients.
Pridinol Mesilate is contraindicated during the first trimester of pregnancy and should be avoided during breastfeeding. Pridinol Mesilate may only be used later in pregnancy after careful consideration, under medical supervision and only if absolutely necessary.
Use with caution in the elderly, and in patients with severe renal and/or hepatic insufficiency, because higher and/or longer-lasting blood levels must be expected. In patients who suffer from hypotension, the risk of circulatory problems (fainting) may be increased. Prindol contains lactose. Patients with the rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.
Centrally acting Skeletal Muscle Relaxants
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
{'Indications': 'Prindol is indicated for the treatment of central and peripheral muscle spasms: lumbar pain, torticollis, general muscle pain, in adults.'}