Halcinonide
Halcinonide cream contains Halcinonide which is a class of primarily synthetic steroid used as topical anti-inflammatory, anti-allergic & antipruritic agent. It is highly effective in corticosteroid-responsive dermatoses because of bi-phasic base. Bi-phasic base offers immediate release of medicaments and prolonged action. On topical application, it can be absorbed from normal intact skin. Inflammation as well as other disease processes in the skin increase percutaneous absorption of halcinonide. Occlusive dressings substantially increase the percutaneous absorption of the drug. Once absorbed through the skin, topical corticosteroid is handled through pharmacokinetic pathways similar to systemically administered corticosteroids.
Adults: Halcinonide should be applied to the affected areas 2-3 times daily. In long term therapy or where lower strength preparation are required, use intermittently.Children: Use minimal amount necessary for effective therapy. For effective treatment use the minimal amount, if necessary.
Halcinonide cream should not be applied to patients sensitive with halcinonide. It should not be used in the treatment of rosacea and discriminately for pruritus.
Zemalog cream is well tolerated. Where adverse reactions occur, they are usually reversible on cessation therapy. However, the following side effects have been reported usually with prolonged uses: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneform eruptions, hypopigmentation, perioral dermatitis, maceration, secondary infection, skin atrophy, striae etc.
Pregnancy Category C. Do not use over extensive areas, in large amounts or for prolonged period. Topical corticosteroids should be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Information is not available whether topical corticosteroids are excreted in quantity unlikely to harm nursing infants, this preparation should be used with caution in nursing mothers.
Zemalog cream applications should not be made with an occlusive dressing to large areas of the body because of the increased risk of systemic toxicity. In general should not be used in presence of infections particularly to the eye. It should not be applied to ulcers of the leg and long term topical use is best to be avoided, specially in children.
Other Topical corticosteroids
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
{'Indications': 'Zemalog cream is suitable for both wet and dry eczematous lesions. For acute and chronic corticosteroid-responsive conditions which may include psoriasis, anogenital eczema, nummular eczema and intertrigo infantile. Contact dermatitis, atopic dermatitis, dermatitis herpetiformis, neurodermatitis, seborrhoeic dermatitis.'}