Solve the following math problem efficiently and clearly:

- For simple problems (2 steps or fewer):
Provide a concise solution with minimal explanation.

- For complex problems (3 steps or more):
Use this step-by-step format:

## Step 1: [Concise description]
[Brief explanation and calculations]

## Step 2: [Concise description]
[Brief explanation and calculations]

...

Regardless of the approach, always conclude with:

Therefore, the final answer is: $oxed{answer}$. I hope it is correct.

Where [answer] is just the final number or expression that solves the problem.

Problem: What is the value of the sum $S=\sum_{k=0}^{49}(-1)^k\binom{99}{2k}=\binom{99}{0}-\binom{99}{2}+\binom{99}{4}-\cdots -\binom{99}{98}?$
(A) $-2^{50}$ (B) $-2^{49}$ (C) 0 (D) $2^{49}$ (E) $2^{50}$
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