Clinical assessment of mineral trioxide aggregate (MTA) as direct pulp capping in young permanent teeth. Direct Pulp Capping with Calcium Hydroxide, Mineral Trioxide Aggregate, and Biodentine in Permanent Young Teeth with Caries: A Randomized Clinical Trial A randomized controlled study of the use of ProRoot mineral trioxide aggregate and Endocem as direct pulp capping materials. A Randomized Controlled Study of the Use of ProRoot Mineral Trioxide Aggregate and Endocem as Direct Pulp Capping Materials: 3-month versus 1-year Outcomes. Comparison of CaOH with MTA for Direct Pulp Capping Mineral trioxide aggregate versus calcium hydroxide for pulpotomy in primary molars. Clinical, radiographic and histologic analysis of the effects of pulp capping materials used in pulpotomies of human primary teeth Comparison of mineral trioxide aggregate and calcium hydroxide as pulpotomy agents in young permanent teeth (apexogenesis). A comparative study on dental pulp response to calcium hydroxide, white and grey mineral trioxide aggregate as pulp capping agents A prospective clinical study of mineral trioxide aggregate for partial pulpotomy in cariously exposed permanent teeth Direct Pulp-Capping with Calcium Enriched Mixture in Primary Molar Teeth: A Randomized Clinical Trial Evaluation of indirect pulp capping using three different materials: A randomized control trial using cone-beam computed tomography Evaluation of two mineral trioxide aggregate compounds as pulp-capping agents in human teeth. Comparison of mineral trioxide aggregate and formocresol as pulp-capping agents in pulpotomized primary teeth. Effect of mineral trioxide aggregate and formocresol pulpotomy on vital primary teeth: a clinical and radiographic study. Evaluation and comparison of mineral trioxide aggregate and biodentine in primary tooth pulpotomy: Clinical and radiographic study Comparison of mineral trioxide aggregate and formocresol as pulp medicaments for pulpotomies in primary molars
UNLABELLED Carious pulp exposure in permanent molars of children is a common incident . Mineral trioxide aggregate is a new material that possesses numerous exciting possibilities for pulp therapy . AIM The purpose of this study was to evaluate the efficiency of MTA as a direct pulp capping agent in young permanent teeth . METHODS Thirty asymptomatic permanent molars with pulp exposures were treated by pulp capping using MTA . At each recall ( 6 12 , 18 and 24 months ) , the teeth were assessed clinical ly , through pulpal sensitivity tests , as well as radiographically to evaluate periapical healing . RESULTS None of the cases reported spontaneous pain at the six months follow up and the pulp showed signs of vitality and absence of periapical radiolucency . At 24 months , the clinical and radiographic success rate was 93 % with evidence of continued root growth . CONCLUSION Pulp capping with MTA is recommended for teeth with carious pulp exposures specially immature teeth with high potential for healing Introduction Direct pulp capping treatment is intended to preserve pulp vitality , to avoid or retard root canal treatment , and , in cases with an open apex , to allow continued root development . Historically , calcium hydroxide ( CH ) was the gold st and ard material , but nowadays calcium silicate material s ( CSMs ) are displacing CH because of their high bioactivity , biocompatibility , sealing ability , and mechanical properties . However , more r and omized clinical trials are needed to confirm the appropriateness of CSMs as replacement material s for CH in direct pulp capping procedures . Methods A r and omized clinical trial was conducted that included 169 patients ( mean age , 11.3 years ) from the Maipo district ( Chile ) . The inclusion criterion was patients with 1 carious permanent tooth with pulpal exposure , a c and i date for a direct pulp capping procedure . The patients were r and omly allocated to one of the experimental groups ( CH , Biodentine , or mineral trioxide aggregate [ MTA ] ) . Clinical follow‐up examinations were performed at 1 week , 3 months , 6 months , and 1 year . The Fisher exact test was performed . Results At the follow‐up examination at 1 week , the patients showed 100 % clinical success . At 3 months , there was 1 failure in the CH group . At 6 months , there were 4 new failures ( 1 in the CH group and 3 in the MTA group ) . At 1 year , there was another failure in the CH group . There were no statistically significant differences among the experimental groups . Conclusions CSMs appear to be suitable material s to replace CH . Although no significant differences were found among the material s studied , Biodentine and MTA offered some advantages over CH . HighlightsThis trial compared the efficacy of calcium hydroxide , MTA , and Biodentine as pulp capping material s in young permanent molars . MTA and Biodentine are suitable material s to replace calcium hydroxide in pulp capping procedures .Pulp capping in carious teeth is a successful treatment when done under good clinical protocol INTRODUCTION The purpose of the present study was to evaluate and compare the short-term clinical outcomes of direct pulp capping using ProRoot MTA ( Dentsply , Tulsa , OK ) or Endocem ( Maruchi , Wonju , Korea ) as capping material s in a prospect i ve r and omized controlled study . MATERIAL S AND METHODS This study was conducted with subjects who were recruited from the pool of patients from the Department of Conservative Dentistry at the Dental College of Yonsei University , Seoul , Korea , between January and May 2013 . Of the 48 teeth confirmed to be eligible for direct pulp capping , a total of 46 teeth were r and omly assigned to either the ProRoot MTA or the Endocem group ( 23 teeth per group ) . Direct pulp capping was performed using these 2 material s , and clinical and radiographic evaluations were performed at 1 , 2 , 4 , and 12 weeks after the treatments . Teeth with no response to pulp vitality test and those exhibiting clinical or radiographic signs and /or symptoms of irreversible pulpitis or pulp necrosis were considered to be failures . RESULTS Thirty-two patients ( 43 teeth ) were examined at the 3-month follow-up ( patient recall rate = 91.4 % ) ; 22 of these teeth were in the ProRoot MTA group , and 21 were in the Endocem group . The overall success rate was 93 % , and the success rates in the ProRoot MTA and Endocem groups were 95.5 % ( 21/22 teeth ) and 90.5 % ( 19/21 teeth ) , respectively . Statistical analyses of these success rates did not reveal any significant difference between the groups ( P = .522 ) . CONCLUSIONS In this r and omized controlled study , no significant difference in the short-term clinical outcomes of direct pulp capping using ProRoot MTA or Endocem as the capping material was found . Furthermore , the favorable short-term outcome success rate of 93 % indicates that direct pulp capping may be a reliable treatment for pulp exposure in adult teeth INTRODUCTION The purpose of this study was to assess the long-term clinical outcomes of direct pulp capping ( DPC ) with ProRoot MTA ( Dentsply , Tulsa , OK ) and Endocem ( Maruchi , Wonju , Korea ) as pulp capping material s. To this end , the 1-year cumulative successes of both material s were evaluated and compared with those of the 3-month outcomes in a prospect i ve , r and omized controlled trial . METHODS Patients were recruited from the Department of Conservative Dentistry of the Yonsei University Dental Hospital , Seoul , South Korea , from January to May 2013 . Of the 48 teeth that met the inclusion criteria , 46 teeth were r and omly allocated to either ProRoot MTA or Endocem groups ( n = 23 ) . Direct pulp capping was performed , and clinical and radiographic examinations were conducted over 1 year after the treatment . Survival analyses were conducted to compare the cumulative successes between ProRoot MTA and Endocem and to evaluate other clinical variables . RESULTS Forty-one teeth were recalled 1 year after the treatments ( recall rate = 89.13 % ) . There were no significant differences between the cumulative successes  of ProRoot MTA and Endocem in either log-rank or Cox proportional hazard regression analyses ( P > .05 ) . Among the other clinical variables , cavity type ( class I , II , III vs class V ) was determined to be significant in both the log-rank test ( P = .001 ) and Cox regression analysis ( P = .006 ) . CONCLUSIONS Both ProRoot MTA and Endocem exhibited similar cumulative successes as direct pulp capping material s up to 1 year . The teeth restored with class V cavities exhibited significantly lower cumulative success rates after direct pulp capping compared with the teeth restored with other types of cavities This practice -based , r and omized clinical trial evaluated and compared the success of direct pulp capping in permanent teeth with MTA ( mineral trioxide aggregate ) or CaOH ( calcium hydroxide ) .  Thirty-five practice s in Northwest PRECEDENT were r and omized to perform direct pulp caps with either CaOH ( 16 practice s ) or MTA ( 19 practice s ) . Three hundred seventy-six individuals received a direct pulp cap with CaOH ( n = 181 ) or MTA ( n = 195 ) . They were followed for up to 2 yrs at regular recall appointments , or as dictated by tooth symptoms . The primary outcomes were the need for extraction or root canal therapy . Teeth were also evaluated for pulp vitality , and radiographs were taken at the dentist ’s discretion . The probability of failure at 24 mos was 31.5 % for CaOH vs. 19.7 % for MTA ( permutation log-rank test , p = .046 ) . This large r and omized clinical trial provided confirmatory evidence for a superior performance with MTA as a direct pulp-capping agent as compared with CaOH when evaluated in a practice -based research network for up to 2 yrs ( Clinical Trials.gov NCT00812887 ) OBJECTIVE To compare the effects of mineral trioxide aggregate ( MTA ) and calcium hydroxide ( CH ) for pulpotomy in primary molars . METHODS A r and omised , bilateral self-controlled clinical trial was design ed to compare the clinical effect of MTA and CH in pulpotomies in primary molars in 4- to 9-year-old children . Children with two similar-sized cavities on bilateral primary molar counterparts requiring pulpotomies were included . The two contralateral molars in each patient were r and omly assigned to MTA or CH treatment . Clinical and radiographic examinations were performed to evaluate the treatment results at post-treatment recall . RESULTS Seventeen pairs of self-controlled contralateral teeth were available for follow-up evaluations . The success rate of MTA was 94.1 % ( 16/17 ) , while the success rate of CH was 64.7 % ( 11/17 ) . Internal root resorption was the most frequent reason for failure in the CH group . Crown discolouration was common in the MTA-treated group . CONCLUSION MTA was more successful than CH for pulpotomies in primary molar teeth , and may be a suitable replacement for CH in primary molar pulpotomies Aim To compare the clinical , radiographic and histological responses of the pulp to mineral trioxide aggregate ( MTA ) , calcium hydroxide ( CH ) and Portl and cement ( PC ) when used as a pulpotomy agent in human primary teeth . Study design Forty-five m and ibular primary molar teeth were r and omly assigned to CH , MTA or PC groups and treated by pulpotomy technique . Methods The teeth were treated by conventional pulpotomy technique , differing only in the capping material for each group . Clinical and radiographic evaluations were recorded at 6- , 12- and 24-month follow-up . Teeth in the regular exfoliation period were further processed for histologic analysis .Statistics Data were tested using parametric tests at a significance level of 5 % . The histological results were expressed descriptively . Results Clinical ly and radiographically , the MTA and PC groups showed 100 % success rates at 6 , 12 and 24 months . In CH group , several teeth presented clinical and radiographic failures detected throughout the follow-up period , and internal resorption was a frequent radiographic finding . Histologic analysis revealed the presence of dentine-like mineralised material deposition obliterating the root canal in the PC and MTA groups . CH group presented , in most of the sections , necrotic areas in the root canals . Conclusions MTA and PC may serve as effective material s for pulpotomies of primary teeth as compared to CH . Although our results are very encouraging , further studies and longer follow-up assessment s are needed in order to determine the safe clinical indication of Portl and cement PURPOSE The purpose of this study was to compare mineral trioxide aggregate ( MTA ) with calcium hydroxide ( Ca(OH)2 ) clinical ly and radiographically as a pulpotomy agent in immature permanent teeth ( apexogenesis ) . METHODS Fifteen children , each with at least 2 immature permanent teeth requiring pulpotomy ( apexogenesis ) , were selected for this study . All selected teeth were evenly divided into 2 test groups . In group 1 , the conventional Ca(OH)2pulpotomy ( control ) was performed , whereas in group 2 , the MTA pulpotomy ( experimental ) was done . The children were recalled for clinical and radiographic evaluations after 3 , 6 , and 12 months . RESULTS The follow-up evaluations revealed failure due to pain and swelling detected at 6 and 12 months postoperative evaluations in only 2 teeth treated with Ca(OH)2 . The remaining 28 teeth appeared to be clinical ly and radiographically successful 12 months postoperatively . Calcific metamorphosis was a radiographic finding in 2 teeth treated with Ca(OH)2 and 4 teeth treated with MTA . CONCLUSIONS Mineral trioxide aggregate showed clinical and radiographic success as a pulpotomy agent in immature permanent teeth ( apexogenesis ) and seems to be a suitable alternative to calcium hydroxide Context : Vital pulp therapy has been known as one of the treatment options to preserve pulp after being exposed by trauma or caries . Aim : To investigate human pulpal response to white and grey mineral trioxide aggregate ( WMTA , GMTA ) and Dycal ( MTA ) as pulp capping agents . Setting and Design : Human volunteers were participated in this r and omized clinical trial . Material s and Methods : This study was conducted on 90 intact first and second premolars of human maxillary and m and ibular teeth . The teeth were r and omly assigned into three groups of 30 each . Under local anesthesia , teeth were exposed and capped either with GMTA , WMTA , or Dycal . After 30 , 60 , and 90 days 10 teeth of each group were extracted and prepared for histologic observation . Statistical Analysis : Histopathologic data were analyzed by χ2 , Kruskal Wallis and Mann Whitney tests . Results : the calcified bridge in teeth that were capped with GMTA was significantly thicker than Dycal at 30 and 60 days ( P= 0.015 and P=0.002 , respectively ) ; whereas WMTA showed significantly thicker calcified bridge than Dycal at 90 days ( P=0.02 ) . In addition , GMTA specimens showed significantly less inflammation compared to Dycal sample s at 90 days interval ( P=0.019 ) . No significant difference was found between GMTA and WMTA in terms of calcified bridge thickness and pulp inflammatory response to the capping material s ( P>0.05 ) . Conclusions : Based on the result of this study , both types of MTA can be suggested as the material s of choice for direct pulp capping procedure instead of Dycal as hard setting calcium hydroxide cement After 2 yrs ' follow-up , mineral trioxide aggregate ( MTA ) appeared suitable for this purpose INTRODUCTION The aim of this trial was to compare clinical and radiographic success rates of direct pulp capping ( DPC ) using a novel bio material called Calcium Enriched Mixture ( CEM ) cement versus Mineral Trioxide Aggregate ( MTA ) in primary molar teeth . MATERIAL S AND METHODS In this r and omized clinical trial 42 deciduous molars in 21 patients who had at least two teeth requiring DPC , were treated . The enrolled patients were between 5 - 8 years . The molar teeth were r and omly divided into two experimental groups . Patients and operators were blinded . The teeth were anaesthetized , caries were removed and after pinpoint exposure of dental pulp , haemostasis was achieved . The exposure points were capped with MTA or CEM cement . All teeth were restored with amalgam . Patients were recalled for the 6-month follow up . Statistical analysis was carried out using McNemar test . RESULTS Thirty-eight teeth were available for follow up ( 19 in each group ) . The radiographic evaluations did not show failure in experimental groups ; however , in clinical examinations one sinus tract was found in CEM cement group . Clinical success rates in CEM cement and MTA groups were 94.8 % and 100 % , respectively . Dentinal bridge formation was not observed in the two experimental groups . CONCLUSION There is no significant difference between treatment outcomes of direct pulp capping with either CEM cement or MTA ; therefore , both bio material s can be used successfully for DPC in primary molar teeth Objective : The objective of this study was to determine the most suitable material for indirect pulp treatment ( IPT ) clinical ly and to determine the thickness ( in mm ) and type of tissue in terms of radiodensity ( in Hounsfield units [ HU ] ) formed after pulp capping using cone-beam computed tomography ( CBCT ) scan . Material s and Methods : A longitudinal interventional single-blind r and omized clinical trial was conducted on 94 children ( 7–12 years ) with a deep carious lesion in one or more primary second molar and permanent first molar without the history of spontaneous pain indicated for indirect pulp capping ( IPC ) procedure . About 109 teeth were treated using three material s , namely , calcium hydroxide ( setting type ) , glass ionomer cement ( Type VII ) , and mineral trioxide aggregate r and omly . The teeth were followed up at an interval of 8 weeks , 6 months , and 1 year for success of IPT as per the American Academy of Pediatric Dentistry clinical criteria . For determining the thickness and type of dentin tissue formed , a CBCT scan was done immediately postoperative and another scan at an interval of 6 months . The scans were compared to evaluate the average thickness of the dentin bridge formed . Results and Conclusions : Success rate for IPC was 96.85 % . A significant difference was obtained in the average thickness of reparative dentin at immediate postoperative and 6-month postoperative values in all three groups suggesting distinct barrier formation . Similar significant findings were obtained in radiodensity of barrier formed ( in HU ) . All three material s were found to be equally suitable as IPC agents suggesting mineral gain AIM The present r and omized , controlled prospect i ve study evaluated the histomorphological response of human dental pulps capped with two grey mineral trioxide aggregate ( MTA ) compounds . METHODOLOGY Pulp exposures were performed on the occlusal floor of 40 human permanent pre-molars . The pulp was capped either with ProRoot ( Dentsply ) or MTA-Angelus ( Angelus ) and restored with zinc oxide eugenol cement . After 30 and 60 days , teeth were extracted and processed for histological examination and the effects on the pulp were scored . The data were subjected to Kruskal-Wallis and Conover tests ( alpha = 0.05 ) . RESULTS In five out of the 40 teeth bacteria were present in pulp tissue . No significant difference was observed between the two material s ( P > 0.05 ) in terms of overall histological features ( hard tissue bridge , inflammatory response , giant cells and particles of capping material s ) . Overall , 94 % and 88 % of the specimens capped with MTA-Angelus and ProRoot , respectively , showed either total or partial hard tissue bridge formation ( P > 0.05 ) . CONCLUSIONS Both commercial material s ProRoot ( Dentsply ) and MTA-Angelus ( Angelus ) produced similar responses in the pulp when used for pulp capping in intact , caries-free teeth PURPOSE The aim of this study was to use clinical , radiographic , and histologic examinations to compare the relative success of gray mineral trioxide aggregate ( MTA ) , white MTA , and formocresol as pulp dressings in pulpotomized primary teeth . METHODS Twenty-four children , each with at least 3 primary molars requiring pulpotomy , were selected for this study 's clinical and radiographic portion . An additional 15 carious primary teeth planned for serial extraction were selected for this study 's histologic portion . All selected teeth were evenly divided into 3 test groups and treated with pulpotomies . Gray MTA was used as the pulp dressing for one third of the teeth , white MTA was the dressing for one third , and the remaining one third were treated with formocresol . The treated teeth selected for the clinical and radiographic evaluations were monitored periodically for 12 months . The treated teeth selected for histologic study were monitored periodically and extracted 6 months postoperatively . RESULTS Four children with 12 pulpotomized teeth failed to return for any follow-up evaluations in the clinical and radiographic study . Of the remaining 60 teeth in 20 patients , 1 tooth ( gray MTA ) exfoliated normally and 6 teeth ( 4 white MTA and 2 formocresol ) failed due to abscesses . The remaining 53 teeth appeared to be clinical ly and radiographically successful 12 months postoperatively . Pulp canal obliteration was a radiographic finding in 11 teeth treated with gray MTA and 1 tooth treated with white MTA . In the histologic study , both types of MTA successfully induced thick dentin bridge formation at the amputation sites , while formocresol induced thin , poorly calcified dentin . Teeth treated with gray MTA demonstrated pulp architecture nearest to normal pulp by preserving the odontoblastic layer and delicate fibrocellular matrix , yet few inflammatory cells or isolated calcified bodies were seen . Teeth treated with white MTA showed a denser fibrotic pattern , with more isolated calcifications in the pulp tissue along with secondary dentin formation . CONCLUSIONS Gray MTA appears to be superior to white MTA and formocresol as a pulp dressing for pulpotomized primary teeth BACKGROUND Pulpotomy is the common therapy for cariously exposed pulps in symptom-free primary molar teeth .  Formocresol ( FC ) is considered the gold st and ard dressing agent for pulpotomy , but concerns have been raised over the years about its safety . Other alternative pulpotomy agents have been investigated and suggested . OBJECTIVE The objective was to evaluate and compare the clinical and radiographic response of FC and white mineral trioxide aggregate ( MTA ) as pulpotomy material s on primary molars . MATERIAL S AND METHODS Fifty primary molars , with deep carious lesion that exposed a vital but asymptomatic pulp , in 37 children aged 4 - 7 years were treated with conventional pulpotomy procedure .  The teeth were divided r and omly into two groups . Group I ( FC ) and group II ( MTA ) . The treated teeth were evaluated clinical ly and radiographically and were followed-up for 12 months . RESULTS At the end of the 12 months follow-up , the clinical success rates for FC and MTA were 81 % and 100 % , respectively . There was a statistically significant difference ( P = 0.04 ) between the clinical success rates of FC and MTA . While the radiographic success rates for FC and MTA were 81 % and 96 % , respectively , there was no statistically significant difference between the radiographic success of MTA and FC . CONCLUSION White MTA showed a higher clinical and radiographic success rate when compared to FC as a pulpotomy agent in vital primary molars , and it has a potential to become a replacement for FC in primary molars Objectives : Pulpotomy is the common therapy for cariously exposed pulps in symptom-free primary molar teeth . For many years , research ers have search ed for an ideal material that allows regeneration of the residual pulp . The purpose of this study was to evaluate the efficacy of mineral trioxide aggregate ( MTA ) , Biodentine as a pulpotomy medicament in primary teeth , both clinical ly and radiographically . Material s and Methods : A total of 25 children ( 50 human primary molar teeth ) aged between 5 and 9 years were selected in this r and omized clinical study . The patients were r and omly assigned to receive the pulpotomy medicaments in either [ Group 1 ] : MTA or [ Group 2 ] : Biodentine . All pulpotomized teeth were restored with stainless steel crowns and evaluated clinical ly and radiologically at 1 , 3 , 6 and 12 months . Statistical analysis using Mann – Whitney U test and Fisher 's exact test , and chi-square test was performed to determine the significant differences between the groups . Results : Clinical and radiological success rates were 96 and 80 % in Group 1 and 96 and 60 % in Group 2 , respectively . There were no significant differences between the groups ( P > 0.05 ) . The radiographic success rates decreased in the controls , but there were no significant differences . Conclusion : Biodentine showed similar clinical and radiographic results as MTA in the 12-month evaluation and can be safely used as a pulpotomy medicament Purpose The aim of this study was to compare the effect of white mineral trioxide aggregate ( MTA ) to that of formocresol ( FC ) as pulp dressing agents in pulpotomised primary molars . Methods In this clinical trial study , 60 lower second primary molars of 46 children were treated by a conventional pulpotomy technique . The teeth were r and omly assigned to the MTA ( experimental ) and FC ( control ) groups by r and om numbered table . Following removal of the coronal pulp and haemostasis , the pulp stumps were covered with an MTA paste in the experimental group . In the control group , FC was placed with a cotton pellet over the pulp stumps . The teeth of both groups were restored with stainless steel crowns . Children arrived for clinical and radiographic follow-up evaluation after 6 , 12 and 24 months . Results The treated teeth in FC group ( n = 18 ) were clinical ly and radiographically successful after 24 months . The radiographic follow-up evaluation revealed one failure ( furcation involvement ) in 18 molars treated with MTA after 24 months . The treated teeth in MTA group were clinical ly successful 24 months postoperatively . Pulp canal obliteration was observed in one of the teeth treated with MTA and four of the teeth treated with FC . Conclusion MTA could be used as a safe medicament for pulpotomy in cariously exposed primary molars and could be a substitute for FC
In conclusion , MTA has a higher clinical success rate for direct pulp capping comparing to calcium hydroxide , and might be a suitable replacement for calcium hydroxide
Direct pulp capping is one of the most common dental practice s in endodontic therapy .
This systematic review and meta- analysis aim to determine whether the effect of mineral trioxide aggregate ( MTA ) and calcium hydroxide for direct pulp capping is different , as measured by the clinical and radiographic analysis .