Effect of mineral trioxide aggregate and formocresol pulpotomy on vital primary teeth: a clinical and radiographic study. Comparative evaluation of formocresol and mineral trioxide aggregate in pulpotomized primary molars--2 year follow up. Comparison of mineral trioxide aggregate and formocresol as pulp medicaments for pulpotomies in primary molars Mineral trioxide aggregate vs. formocresol in pulpotomized primary molars: a preliminary report. Success of mineral trioxide aggregate in pulpotomized primary molars. Randomized controlled trial of mineral trioxide aggregate and formocresol for pulpotomy in primary molar teeth. The effectiveness of mineral trioxide aggregate, calcium hydroxide and formocresol for pulpotomies in primary teeth. Success rates of mineral trioxide aggregate, ferric sulfate, and formocresol pulpotomies: a 24-month study. Long-term evaluation of pulpotomy in primary molars using mineral trioxide aggregate or formocresol. Comparison of gray mineral trioxide aggregate and diluted formocresol in pulpotomized primary molars: a 6- to 24-month observation. Mineral trioxide aggregate versus calcium hydroxide for pulpotomy in primary molars. Mineral trioxide aggregate produces superior outcomes in vital primary molar pulpotomy. Mineral Trioxide Aggregate Partial Pulpotomy Versus Formocresol Pulpotomy: A Randomized, Split-Mouth, Controlled Clinical Trial with 24 Months Follow-Up. Comparative evaluation of formocresol and mineral trioxide aggregate as pulpotomy agents in deciduous teeth. Comparison of mineral trioxide aggregate and formocresol as pulp-capping agents in pulpotomized primary teeth. Comparison of Ferric Sulfate Combined Mineral Trioxide Aggregate Pulpotomy and Zinc Oxide Eugenol Pulpectomy of Primary Maxillary Incisors: An 18-month Randomized, Controlled Trial. Dentin bridge formation after mineral trioxide aggregate (MTA) pulpotomies in primary teeth.
BACKGROUND Pulpotomy is the common therapy for cariously exposed pulps in symptom-free primary molar teeth .  Formocresol ( FC ) is considered the gold st and ard dressing agent for pulpotomy , but concerns have been raised over the years about its safety . Other alternative pulpotomy agents have been investigated and suggested . OBJECTIVE The objective was to evaluate and compare the clinical and radiographic response of FC and white mineral trioxide aggregate ( MTA ) as pulpotomy material s on primary molars . MATERIAL S AND METHODS Fifty primary molars , with deep carious lesion that exposed a vital but asymptomatic pulp , in 37 children aged 4 - 7 years were treated with conventional pulpotomy procedure .  The teeth were divided r and omly into two groups . Group I ( FC ) and group II ( MTA ) . The treated teeth were evaluated clinical ly and radiographically and were followed-up for 12 months . RESULTS At the end of the 12 months follow-up , the clinical success rates for FC and MTA were 81 % and 100 % , respectively . There was a statistically significant difference ( P = 0.04 ) between the clinical success rates of FC and MTA . While the radiographic success rates for FC and MTA were 81 % and 96 % , respectively , there was no statistically significant difference between the radiographic success of MTA and FC . CONCLUSION White MTA showed a higher clinical and radiographic success rate when compared to FC as a pulpotomy agent in vital primary molars , and it has a potential to become a replacement for FC in primary molars AIM The aim of the present study was to clinical ly and radiographically evaluate Mineral Trioxide Aggregate ( MTA ) as an agent for pulpotomy in primary teeth and to compare it with that of Formocresol ( FC ) pulpotomy . METHOD Seventy first and second primary m and ibular molars of children were chosen on patients who required minimum two pulpotomies in either arch or same arch . After the st and ardized technique of Pulpotomy with MTA and Formocresol , all molars were treated with a thick mix of Zinc oxide Eugenol cement into the coronal pulp chamber followed by preformed stainless steel crown . The children were followed up for clinical and radio graphical examination after 6 , 12 and 24 month for Pain , Swelling , Sinus/fistula , Periapical changes , Furcation radiolucency and internal resorption . RESULTS MTA represents 97 % clinical success rate in comparison to Formocresol with 85 % success . Radiographically also MTA showed more promising results with 88.6 % success in comparison to Formocresol with 54.3 % . CONCLUSIONS Thus , MTA pulpotomy has emerged as an easier line of treatment to save the premature loss of primary teeth due to caries or trauma Purpose The aim of this study was to compare the effect of white mineral trioxide aggregate ( MTA ) to that of formocresol ( FC ) as pulp dressing agents in pulpotomised primary molars . Methods In this clinical trial study , 60 lower second primary molars of 46 children were treated by a conventional pulpotomy technique . The teeth were r and omly assigned to the MTA ( experimental ) and FC ( control ) groups by r and om numbered table . Following removal of the coronal pulp and haemostasis , the pulp stumps were covered with an MTA paste in the experimental group . In the control group , FC was placed with a cotton pellet over the pulp stumps . The teeth of both groups were restored with stainless steel crowns . Children arrived for clinical and radiographic follow-up evaluation after 6 , 12 and 24 months . Results The treated teeth in FC group ( n = 18 ) were clinical ly and radiographically successful after 24 months . The radiographic follow-up evaluation revealed one failure ( furcation involvement ) in 18 molars treated with MTA after 24 months . The treated teeth in MTA group were clinical ly successful 24 months postoperatively . Pulp canal obliteration was observed in one of the teeth treated with MTA and four of the teeth treated with FC . Conclusion MTA could be used as a safe medicament for pulpotomy in cariously exposed primary molars and could be a substitute for FC PURPOSE The aim of this study was to compare the effect of mineral trioxide aggregate ( MTA ) to that of formocresol ( FC ) as pulp dressing agents in pulpotomized primary molars with carious pulp exposure . METHODS Forty-five primary molars of 26 children were treated by a conventional pulpotomy technique . The teeth were r and omly assigned to the MTA ( experimental ) or FC ( control ) group by a toss of a coin . Following removal of the coronal pulp and hemostasis the pulp stumps were covered with an MTA paste in the experimental group . In the control group , FC was placed with a cotton pellet over the pulp stumps for 5 minutes and removed ; the pulp stumps were then covered by zinc oxide-eugenol ( ZOE ) paste . The teeth of both groups were restored with stainless steel crowns . Eighteen children with 32 teeth arrived for clinical and radiographic follow-up evaluation ranging from 6 to 30 months . RESULTS The follow-up evaluations revealed only one failure ( internal resorption detected at a 17 months postoperative evaluation ) in a molar treated with formocresol . None of the MTA-treated teeth showed any clinical or radiographic pathology . Pulp canal obliteration was observed in 9 of 32 ( 28 % ) evaluated molars . This finding was detected in 2 out of the 15 teeth treated with FC ( 13 % ) and in 7 out of the 17 treated with MTA ( 41 % ) . CONCLUSION MTA showed clinical and radiographic success as a dressing material following pulpotomy in primary teeth and seems to be a suitable replacement for formocresol in primary teeth UNLABELLED The aim of the present study was to compare , clinical ly and radiographically , the mineral trioxide aggregate ( MTA ) to formocresol ( FC ) when used as medicaments in pulpotomized vital human primary molars . METHODS The sample consisted of 120 primary molars , all teeth were treated with the same conventional pulpotomy technique .  Sixty molars received FC and 60 received MTA throughout a r and om selection technique . RESULTS At the end of 24-month evaluation period , 74 molars ( 36 FC , 38 MTA ) were available for clinical and radiographic evaluation . None of the MTA treated teeth showed any clinical or radiographic pathology , while the FC group showed a success rate of 86.8 % radiographically and 98.6 % clinical ly . The difference between the two groups in the radiographic outcomes was statistically significant . It was concluded that MTA treated molars demonstrated significantly greater success .  MTA seems to be a suitable replacement for formocresol in pulpotomized primary teeth AIM To compare the outcome after 6 months of the application of formocresol ( FC ) or mineral trioxide aggregate ( MTA ) during pulpotomy in primary molar teeth . METHODOLOGY A maximum of 126 children ( aged 5 - 9 years ) with carious primary teeth that required pulpotomy were selected . Following r and omization , a st and ard pulpotomy preparation was undertaken , and the coronal pulp removed and bleeding arrested . In the FC group , cotton balls , soaked in FC , were placed for 5 min , and then the pulp chamber was filled with Zonalin , a pulpotomy agent . In the MTA group , a 1-mm-thick paste of MTA was used as a pulpotomy agent . The crowns in both groups were restored with amalgam or glass ionomer .  The teeth of 100 patients were evaluated and compared clinical ly and radiographically after 3 and 6 months . RESULTS No signs of clinical failure were observed at the 3- and 6-month follow-up appointments in either group . There were no significant differences in the radiographic findings of the teeth and surrounding tissue at the 3-month follow-up . However , at the 6-month follow-up , significantly more cases ( P = 0.036 ) with root resorption were seen in the FC group ; no cases of resorption occurred amongst the MTA cases . The surrounding tissue showed radiographic signs of post-treatment disease in four FC cases ; none was seen in the MTA cases . CONCLUSION After 6 months , pulpotomy with MTA was associated with fewer cases of root resorption and post-treatment disease .  MTA appears to be a reliable alternative material for pulpotomy in primary molar teeth AIM To compare the effectiveness of mineral trioxide aggregate ( MTA ) , calcium hydroxide ( CH ) and formocresol ( FC ) as pulp dressing agents in carious primary teeth . METHODOLOGY Forty-five primary m and ibular molars with dental caries in 23 children [ AUTHOR QUERY : How many children ? ] between 5 and 9 years old were treated by a conventional pulpotomy technique . The teeth were r and omly assigned to the experimental ( CH or MTA ) or control ( FC ) groups . After coronal pulp removal and haemostasis , remaining pulp tissue was covered with MTA paste or CH powder in the experimental groups . In the control group , diluted FC was placed with a cotton pellet over the pulp tissue for 5 min and removed ; the pulp tissue was then covered with zinc oxide-eugenol ( ZOE ) paste . All teeth were restored with reinforced ZOE base and resin modified glass-ionomer cement .  Clinical and radiographic successes and failures were recorded at 3 , 6 , 12 , 18 and 24 month follow-up . RESULTS Forty-three teeth were available for follow-up . In the FC and MTA groups , 100 % of the available teeth were clinical ly and radiographically successful at all follow-up appointments ; dentine bridge formation could be detected in 29 % of the teeth treated with MTA . In the CH group , 64 % of the teeth presented clinical and radiographic failures detected throughout the follow-up period , and internal resorption was a frequent radiographic finding . CONCLUSIONS Mineral trioxide aggregate was superior to CH and equally as effective as FC as a pulpotomy dressing in primary m and ibular molars . Internal resorption was the most common radiographic finding up to 24 month after pulpotomies performed with CH PURPOSE The purpose of this study was to evaluate the total success rates of mineral trioxide aggregate ( MTA ) , ferric sulfate ( FS ) , and formocresol ( FC ) as pulpotomy agents in primary molars . METHODS A r and omized , split-mouth study design was used in 32 healthy 5- to 7-year-old children with 128 carious primary molars without clinical or radiographic evidence of pulp degeneration . The pulpotomy agents were assigned as follows : Group 1=MTA ; Group 2=FS ; Group 3=1:5 diluted Buckley 's FC ; and Group 4=zinc oxide eugenol ( ZOE ) base . Clinical and radiographic follow-up at 6 , 12 , and 24 months used the following criteria : pain ; swelling ; sinus tract ; mobility ; internal root resorption ; and furcation and /or periapical bone destruction . The data were analyzed using chi-square . RESULTS No significant differences in success rates were found among the groups at 6 and 12 months . Success rates in groups 1 to 4 at 24 months were 96 % , 88 % , 88 % , and 68 % respectively . There was a significant difference ( P<.001 ) between the MTA and ZOE groups at 24 months . CONCLUSIONS ZOE , as the only pulpotomy medicament , had a significantly lower success rate than MTA . No significant differences were observed , among the 3 experimental material s ( MTA , FC , and FS ) at 2 years follow-up PURPOSE The objective of this study was to assess the effect of mineral trioxide aggregate ( MTA ) as pulp dressing material following pulpotomy in primary molars with carious pulp exposure and compare them to those of formocresol ( FC ) . METHODS Of 33 children , primary molars treated via a conventional pulpotomy technique  were r and omly assigned to the MTA  group ( 33 teeth ) or FC  group ( 29 teeth ) . Clinical and radiographic follow-up ranged between 4 and 74 months . The mean follow-up time was 38 months , with no difference between the groups . Twenty-nine teeth were followed until uneventful shedding ( mean=33 months ) . Failures were detected after a mean period of 16 months ( range=4 to 30 ) . RESULTS The success rate of pulpotomy was 97 % for MTA ( 1 failure ) and 83 % for FC ( 5 failures ) . Eight teeth presented internal resorption . In 4 of them ( 2 of each group ) , progress of the resorption process stopped and the pulp tissue was replaced by a radioopaque calcified tissue . Pulp canal obliteration was observed in 58 % of the MTA group and in 52 % of the FC group ( total=55 % ) . CONCLUSIONS MTA showed a higher ( though not statistically significant ) long-term clinical and radiographic success rate than formocresol , and can be recommended as its replacement as , unlike FC , MTA does not induce undesirable responses PURPOSE The purpose of this multisite , multioperator , prospect i ve , r and omized , controlled clinical trial was to evaluate 2-year outcomes of diluted formocresol ( DFC ) compared to gray mineral trioxide aggregate ( GMTA ) as pulpotomy medicaments . METHODS Following the st and ard pulpotomy procedure , the pulp stumps of 252 primary molars in 168 healthy children were r and omly covered with GMTA or DFC . Pulp chambers were filled with Intermediate Restorative Material ( IRM ( ® ) ) and teeth were restored with stainless steel crowns . At each follow-up appointment , the clinical status of the treated tooth was assessed and radiographs were taken . A total of 694 clinical and radiographic evaluations were analyzed . RESULTS Gender , study site , arch type , and tooth type did not influence treatment outcome . At the combined 6- to 24-month follow-up , clinical success in the DFC group was no different than for the GMTA group . Radiographically , a significantly lower success rate was found in the DFC group vs the MTA group at all time points ( P<.01 ) . Dentin bridge formation was observed at a significantly higher frequency among the GMTA group ( P<.01 ) , while internal root resorption was observed at a higher frequency in the DFC group ( P<.01 ) . CONCLUSION At the combined 6- to 24-month follow-up , gray mineral trioxide aggregate demonstrated significantly better radiographic outcomes vs diluted formocresol as pulpotomy medicaments OBJECTIVE To compare the effects of mineral trioxide aggregate ( MTA ) and calcium hydroxide ( CH ) for pulpotomy in primary molars . METHODS A r and omised , bilateral self-controlled clinical trial was design ed to compare the clinical effect of MTA and CH in pulpotomies in primary molars in 4- to 9-year-old children . Children with two similar-sized cavities on bilateral primary molar counterparts requiring pulpotomies were included . The two contralateral molars in each patient were r and omly assigned to MTA or CH treatment . Clinical and radiographic examinations were performed to evaluate the treatment results at post-treatment recall . RESULTS Seventeen pairs of self-controlled contralateral teeth were available for follow-up evaluations . The success rate of MTA was 94.1 % ( 16/17 ) , while the success rate of CH was 64.7 % ( 11/17 ) . Internal root resorption was the most frequent reason for failure in the CH group . Crown discolouration was common in the MTA-treated group . CONCLUSION MTA was more successful than CH for pulpotomies in primary molar teeth , and may be a suitable replacement for CH in primary molar pulpotomies PURPOSE The purpose of this study was to investigate the outcomes of vital primary molar pulpotomy  when there is no direct contact between eugenol and the vital pulp . Four pulpotomy techniques were compared : ( 1 ) ferric sulfate ( FS ) pulpotomy ; ( 2 ) eugenol-free FS pulpotomy ; ( 3 ) mineral trioxide aggregate ( MTA ) pulpotomy ; and ( 4 ) FS/MTA pulpotomy . METHODS The pulpotomy technique assigned to each molar was determined by r and om selection . Two blinded , disinterested raters classified each molar into 1 of 3 radiographic outcomes : ( 1 ) N = normal molar without pathologic change ; ( 2 ) Po = pathologic change present , follow-up recommended ; ( 3 ) Px = pathologic change present , extract . RESULTS A total of 92 patients with 227 pulpotomy-treated molars returned for at least 1 recall examination . Median follow-up for molars was 24 months ( range=12 - 38 months ) . MTA molars demonstrated significantly fewer Px radiographic outcomes than FS molars ( P=.002 , chi-square test ) . Eugenol-free FS molars demonstrated significantly more Px radiographic outcomes than MTA ( P<.001 , chi-square test ) or FS/MTA ( P=.002 , chi-square test ) molars . Significantly lower survival was demonstrated for eugenol-free FS molars compared to MTA molars ( P=.02 , log-rank test ) over 6 to 38 months . CONCLUSIONS Outcomes for mineral trioxide aggregate pulpotomy were superior to ferric sulfate and eugenol-free ferric sulfate pulpotomy after a median follow-up of 2 years PURPOSE The purpose of this study was to evaluate the clinical and radiographic success rates of mineral trioxide aggregate partial pulpotomy ( PP ) compared to formocresol pulpotomy ( FP ) in human primary molars . METHODS In this r and omized , controlled , split-mouth , clinical trial , 25 healthy five- to eight-year-olds , with 50 carious primary m and ibular second molars lacking clinical and radiographic evidence of pulp pathology , were selected . The selected teeth were r and omly assigned into two groups , PP and FP , for vital pulp therapy . Stainless steel crowns were placed as final restorations for both groups . Clinical and radiographic evaluation at six , 12 , and 24 months used the following criteria for failure : pain ; swelling ; sinus tract ; mobility ; internal or external root resorption ; furcation or periapical radiolucency ; and widening of periodontal ligament space . The data were analyzed using a binary logistic generalized estimating equation model . RESULTS At the 12-month and 24-month follow-ups , one child and three children , respectively , were lost to follow-up . At the 24-month follow-up , the clinical , radiographic , and overall success rates of PP were 90.9 percent , 90.5 percent , and 81.8 percent versus FP success of 100 percent , 95.2 percent , and 95.2 percent , respectively . CONCLUSION There were no significant differences between clinical , radiographic , and overall success rate of mineral trioxide aggregate partial pulpotomy and formocresol pulpotomy overall 24 months AIM To evaluate and compare mineral trioxide aggregate ( MTA ) and formocresol as pulpotomy medicaments by clinical and radiographic assessment s and to assess the histological features of both pulpotomy medicaments in deciduous teeth . MATERIAL S AND METHODS This study was performed on 100 m and ibular deciduous molar teeth requiring pulpotomy treatment . Children between age four and six years were r and omly selected and divided into formocresol or MTA group . The patients were recalled after 3 , 6 , 9 , 12 months respectively and evaluated clinical ly and radiographically . Histological assessment was done on lower deciduous canine teeth , which were undergoing serial extraction for interceptive orthodontic purpose . Pulpotomy was done on four teeth with formocresol and another four teeth with MTA . The teeth were extracted after six months following pulpotomy procedure and histologically evaluated . Two freshly extracted carious teeth were taken as controls . RESULTS Clinical and radiographic criteria were laid and Chi analysis revealed significant difference in mobility ( P≤0.05 ) , periodontal ligament widening ( P≤0.01 level ) and inter - radicular radiolucency ( P≤0.02 level ) between two groups at the end of 12 months . Histologically , in MTA group , a layer of new dentine formation with less dentinal tubules at the pulpotomized site was found . In formocresol group , increased inflammatory cells , a zone of atrophy , were noted in radicular portion of pulp . CONCLUSION MTA is superior to formocresol clinical ly , radiographically . Histological analysis showed better reparative ability with hard tissue barrier formation with MTA compared to formocresol PURPOSE The aim of this study was to use clinical , radiographic , and histologic examinations to compare the relative success of gray mineral trioxide aggregate ( MTA ) , white MTA , and formocresol as pulp dressings in pulpotomized primary teeth . METHODS Twenty-four children , each with at least 3 primary molars requiring pulpotomy , were selected for this study 's clinical and radiographic portion . An additional 15 carious primary teeth planned for serial extraction were selected for this study 's histologic portion . All selected teeth were evenly divided into 3 test groups and treated with pulpotomies . Gray MTA was used as the pulp dressing for one third of the teeth , white MTA was the dressing for one third , and the remaining one third were treated with formocresol . The treated teeth selected for the clinical and radiographic evaluations were monitored periodically for 12 months . The treated teeth selected for histologic study were monitored periodically and extracted 6 months postoperatively . RESULTS Four children with 12 pulpotomized teeth failed to return for any follow-up evaluations in the clinical and radiographic study . Of the remaining 60 teeth in 20 patients , 1 tooth ( gray MTA ) exfoliated normally and 6 teeth ( 4 white MTA and 2 formocresol ) failed due to abscesses . The remaining 53 teeth appeared to be clinical ly and radiographically successful 12 months postoperatively . Pulp canal obliteration was a radiographic finding in 11 teeth treated with gray MTA and 1 tooth treated with white MTA . In the histologic study , both types of MTA successfully induced thick dentin bridge formation at the amputation sites , while formocresol induced thin , poorly calcified dentin . Teeth treated with gray MTA demonstrated pulp architecture nearest to normal pulp by preserving the odontoblastic layer and delicate fibrocellular matrix , yet few inflammatory cells or isolated calcified bodies were seen . Teeth treated with white MTA showed a denser fibrotic pattern , with more isolated calcifications in the pulp tissue along with secondary dentin formation . CONCLUSIONS Gray MTA appears to be superior to white MTA and formocresol as a pulp dressing for pulpotomized primary teeth PURPOSE The purpose of this study was to compare outcomes and survival of ferric sulfate with mineral trioxide aggregate ( FS+MTA ) pulpotomy and root canal therapy ( RCT ) in carious vital primary maxillary incisors . METHODS In this parallel group noninferiority trial , asymptomatic carious vital primary incisors with pulp exposure in healthy 18- to 46-month-olds were allocated r and omly to receive FS+MTA pulpotomy or RCT between September 2010 and September 2012 . Each incisor was classified into one of the following radiographic outcomes : N ( incisor without pathologic change ) ; Po ( pathologic change present , follow-up recommended ) ; Px ( pathologic change present , extract . ) Clinical findings and incisor survival were secondary outcomes . RESULTS Seventy subjects were enrolled with a total of 172 incisors . Twelve- and 18-month radiographic outcomes demonstrated no statistical difference between FS+MTA pulpotomy and RCT incisors for Px outcomes ( P=0.38 ; odds ratio equals 0.60 ; 95 percent confidence interval equals 0.19 to 1.89 ; chi-square test ) . There was no statistical differences in clinical outcomes for FS+MTA pulpotomy and RCT at 12 and 18 months ( P=0.51 ; Fisher 's exact test ) or survival for FS+MTA pulpotomy and RCT incisors ( P=0.11 ; log-rank test ) . CONCLUSIONS Ferric Sulfate with Mineral Trioxide Aggregate ( FS+MTA ) is an alternative to RCT for vital primary incisors PURPOSE To evaluate the results of using mineral trioxide aggregate ( MTA ) in pulpotomy procedures in primary teeth . METHODS Seven patients were selected and a total of 20 molars and two canines were treated with pulpotomy procedures using MTA instead of formocresol . RESULTS After 6 months , 55 % of the molars and 100 % of the canines treated showed radiographic signs of dentin bridge formation . Also , 6 months after treatment , 60 % of the molars showed root canal calcification ( obliteration ) . Color change of the crown of the canines treated was noticeable . No clinical or radiographic signs of pathology was observed
Conclusion : Primary molars pulpotomy with MTA have better clinical and radiographic success rates than FC . (
Introduction : There are various studies looking at the effects of formocresol ( FC ) and mineral trioxide aggregate ( MTA ) on pulpotomy of primary molars .
This is a systematic review of literature comparing the success rates of MTA and FC in pulpotomy of primary molars .