[Study on effect of moxibustion and guben yiliu III combined with chemotherapy in treating middle-late stage malignant tumor]. [Observation on therapeutic effect of herb-partitioned moxibustion on fibromyalgia syndrome]. [Effects of warming needle moxibustion on improvement of gastrointestinal and immune function in patients with postoperation of colorectal cancer]. Efficacy and safety of ginger-salt-indirect moxibustion for urge urinary incontinence after stroke: protocol for a pilot multicentre randomised controlled trial The Effect of Hand Acupuncture Therapy and Hand Moxibustion Therapy on Premenstrual Syndrome Among Korean Women [Observation on therapeutic effect of acupuncture and moxibustion on hyperemesis gravidarum]. Observation of the efficacy of acupuncture and moxibustion in 62 cases of chronic colitis. The effectiveness of moxibustion for the treatment of functional constipation: a randomized, sham-controlled, patient blinded, pilot clinical trial Comparison of heat-sensitive moxibustion versus fluticasone/salmeterol (seretide) combination in the treatment of chronic persistent asthma: design of a multicenter randomized controlled trial [Randomized controlled study on ginger-salt-partitioned moxibustion at shenque (CV 8) on urination disorders poststroke]. Moxibustion for pain relief in patients with primary dysmenorrhea: A randomized controlled trial The Effectiveness of Moxibustion: An Overview During 10 Years Effects of infrared laser moxibustion on cancer-related fatigue in breast cancer survivors Comparison of the Efficacy between Conventional Moxibustion and Smoke-Free Moxibustion on Knee Osteoarthritis: A Randomized Controlled Trial Acupuncture As an Integrative Approach for the Treatment of Hot Flashes in Women With Breast Cancer: A Prospective Multicenter Randomized Controlled Trial (AcCliMaT). [Post-stroke depression treated with acupuncture and moxibustion: an evaluation of therapeutic effect and safety]. [Observation on clinical effects of moxibustion stimulation of different sensitive status acupoints for knee osteoarthritis].
OBJECTIVE To observe the complementary function of moxibustion and Guben Yiliu III ( GBYL ) , a Chinese herbal composite preparation , in combination with chemotherapy . METHODS Eighty-one patients of middle-late stage malignant tumor were r and omly divided into three groups , 16 in the control group treated with chemotherapy alone , 35 in the TCM group treated with chemotherapy combined GBYL and 30 in the TCM combined moxibustion group . The therapeutic effect of treatment was evaluated according to the immediate effect , living quality scoring , etc . RESULTS The comprehensive living quality score and Karnofsky score dropped significantly in the control group after treatment with significant increase of pain score and decrease of tongue figure score ( P < 0.05 or P < 0.01 ) . In the TCM group , the former two criteria lowered less than those in the control group , but no significant difference in the latter two criteria was shown . For those in the TCM combined moxibustion group , all the four criteria were improved better than those in the control group ( P < 0.01 or P < 0.05 ) . CONCLUSION GBYL combined or not combined with moxibustion could improve the living quality of patients received chemotherapy OBJECTIVE To observe the clinical therapeutic effect of herb-partitioned moxibustion combined with medication on fibromyalgia syndrome . METHODS Sixty cases were r and omly divided into a treatment group and an observation group , 30 cases in each group . The observation group was treated with oral administration of amitriptyline , and the treatment group with oral administration of amitriptyline and herb-partitioned moxibustion at Dazhui ( GV 14 ) , Zhiyang ( GV 9 ) , Mingmen ( GV 4 ) , Shenshu ( BL 23 ) , Guanyuan ( CV 4 ) , Shenque ( CV 8) , and direct moxibustion at Baihui ( GV 20 ) . After treatment of one month , their clinical therapeutic effect , and changes of the number of pain points and the scores of VAS and the HAMD depression rating scale were observed . RESULTS The total effective rate was 93.3 % in the treatment group and 56.7 % in the observation group , the former being better than the latter ( P<0.01 ) . The scores of VAS and HAMD and the number of pain points after treatment in the treatment group were better than those before treatment ( P<0.01 ) ; the score of HAMD and the number of pain points after treatment in the observation group were superior to those before treatment ( P<0.01 ) , and there was no significant difference in the score of VAS before and after treatment ( P>0.05 ) . After treatment , the score of HAMD and the number of pain points in the treatment group were significantly better than those in the observation group ( P<0.01 ) , and there was no significant difference between the two groups in the score of VAS ( P>0.05 ) . CONCLUSION The herb-partitioned moxibustion combined with medication is an effective therapy for fibromyalgia syndrome OBJECTIVE To verify the clinical therapeutic effect of warming needle moxibustion on improvement of the gastrointestinal and immune function in patients with postoperation of colorectal cancer . METHODS One hundred and five patients with postoperation of colorectal cancer were r and omly divided into an acupuncture and moxibustion group , a Chinese medicine group and a routine treatment group , 35 cases in each group . They were all treated with gastrointestinal decompression and fluid replacement after operation . The acupuncture and moxibustion group was also treated with warming needle moxibustion on the 1st day after operation , and Zusanli ( ST 36 ) , Shangjuxu ( ST 37 ) and Xiajuxu ( ST 39 ) etc . were selected , once a day for 10 days , and the Chinese medicine group with Simo Decoction oral solution , three times daily for 10 days . The gastrointestinal function , peripheral blood components and changes of T lymphocyte and NK cells in postoperative patients were observed . RESULTS The time of the first bowel sound , exhaust and defecation in the acupuncture and moxibustion group were all shorter than those in the Chinese medicine group and the routine treatment group ( P<0.05 , P<0.01 ) . On the 10th day after operation , the percentages distribution of lymphocyte and neutrophil in the acupuncture and moxibustion group were better than those in the Chinese medicine group and the routine treatment group ( all P<0.05 ) . The acupuncture and moxibustion group was also superior to the Chinese medicine group and the routine treatment group in improving the subgroup of T lymphocyte , NK cells and the digestive system symptoms ( all P<0.05 ) . CONCLUSION Warming needle moxibustion has a good therapeutic effect on gastrointestinal function and can regulate bidirectionally peripheral blood lymphocyte and neutrophile granulocyte and improve the T lymphocyte subgroup and NK cells so as to promote the recovery of immune function in patients with colorectal cancer after operation Introduction Ginger-salt-indirect moxibustion is widely applied to treat urge urinary incontinence after stroke , which is a common complication in stroke survivors . Moxa cone moxibustion and moxa box moxibustion are the main techniques of ginger-salt-indirect moxibustion . Our previous study had shown that ginger-salt-indirect moxibustion using moxa cones was feasible and effective for urination disorders post-stroke . This pilot study aims to assess the feasibility of conducting research to evaluate the efficacy and safety of ginger-salt-indirect moxibustion for patients with post-stroke urge urinary incontinence . Methods and analysis This is a multicentre , prospect i ve , single-blinded , pilot r and omised controlled trial . 120 eligible patients will be r and omly allocated to three groups . Treatment group A ( n=40 ) will receive moxa cone moxibustion and routine care ; treatment group B ( n=40 ) will receive moxa box moxibustion and routine care ; control group ( n=40 ) will only receive routine care for stroke recovery . The entire moxibustion treatment will consist of a total of 28 sessions during the course of 4 weeks . The primary outcome measure will be the increase in mean volume per void assessed at week 4 from the first moxibustion session ( baseline ) . Secondary outcome measures will include mean frequency of urination per day and quality of life assessment s measured by completion of the Incontinence Quality of Life Question naire and Barthel Index . All outcome measures will be assessed at baseline and at 4 and 16 weeks from baseline . Adverse events in the three groups will be recorded to assess the safety of moxibustion . Ethics and dissemination Research ethics was approved by the Research Ethical Committee of Beijing Hospital of Traditional Chinese Medicine Affiliated to the Capital Medical University ( ref : 2013BL-094 ) . Written informed consent will be obtained from all participants . Study results will be published in peer review ed journals . Trial registration number IS RCT N 44706974 Premenstrual syndrome ( PMS ) symptoms can reduce quality of life and impair daily functioning . This study examined the effects of Korean h and acupuncture therapy ( HAT ) and h and moxibustion therapy ( HMT ) on symptom severity in Korean women with PMS . This quasi-experimental pilot study based on the khi , yin , yang , and the five elements theory used a nonequivalent control group pretest — posttest design . Experimental groups received 10 sessions of either HAT or HMT treatment . Outcome measures included menstrual symptom severity as measured with the Menstrual Symptom Severity List and skin temperature change measured with Digital Infrared Thermographic Imaging . Both experimental groups had significantly reduced overall PMS symptom severity scores following therapy as compared to women in the control group .  The HMT but not the HAT group showed improved flow of khi and balanced skin temperature in symmetric body areas . HAT and HMT may be effective strategies for women to reduce PMS symptoms OBJECTIVE To search for the best method for treatment of hyperemesis gravidarum . METHODS One hundred and fifty cases of hyperemesis gravidarum were r and omly divided into 3 groups , acup-moxibustion group , Chinese drug group and Western medicine group , 50 cases in each group . The acup-moxibustion group were treated with acupuncture at Zhongwan ( CV 12 ) , Neiguan ( PC 6 ) , Zusanli ( ST 36 ) and Yinlingquan ( SP 9 ) , and after arrival of qi , mild warming moxibustion of 10 - 15 min was added ; the Chinese drug group with oral administration of modified Suye Huanglian Decoction , and the Western medicine group with oral administration of phenobarbital and supplement of water and electrolyte . RESULTS The total effective rate was 86.0 % in the acup-moxibustion group , 42.0 % in the Chinese drug group and 38.0 % in the Western medicine group with a significant difference among the 3 groups ( P < 0.05 ) , the therapeutic effect in the acup-moxibustion group being the best . CONCLUSION Acup-moxibustion is the best method for hyperemesis gravidarum 62 patients with chronic colitis were r and omly divided into two groups . Acupuncture and moxibustion at acupoints such as Tianshu ( St 25 ) , Guanyuan ( Ren 4 ) were applied in the treatment group , and western drugs were applied in the control group . The results showed that acupuncture and moxibustion had a marked curative effective with few side effects , and therefore was readily acceptable to the patients Background Moxibustion is an ancient traditional medicine using burning mugworts to stimulate acupuncture points . The aim of this study was to investigate the safety and efficacy of moxibustion for the treatment of constipation using a r and omized , sham-controlled , participant-blinded , pilot trial . Methods Twenty-six participants ( identified with either qi ( vital energy ) deficiency or qi excess syndrome ) were r and omly divided into either a moxibustion or sham group . Participants were treated with real or sham moxibustion at 4 acupuncture points , ST23 and ST27 , bilaterally , 3 times per week for four weeks . The primary outcome was the frequency of defecations ; secondary outcomes were the Bristol stool form scale ( BSS ) and the constipation assessment scale ( CAS ) . Results Of the 26 participants that were r and omized , 24 completed the study .  Defecation frequency , BSS , and CAS showed no difference between the moxibustion and sham groups . The differences were -0.25 ( 95 % CI : -2.08 , 1.58 , p = 0.78 ) , -1.22 ( 95 % CI : -2.7 , 0.26 , p = 0.1 ) , 0.91 ( 95 % CI : -1.46 , 3.28 , p = 0.44 ) in defecation frequency , BSS , CAS , respectively . The defecation frequency increased from an average of 3.3 to 4.6 times per week in the moxibustion group ( 1.5[-0.5 , 2 ] , p = 0.06 ) and from 2.7 to 3.7 stools per week in the sham group ( 1[-1 , 2 ] , p = 0.15 ) after four weeks of treatment . The difference between participants with a deficiency or an excess syndrome , determined based on assessment of sweat , facial features , pain , body energy , and pulse type , was significant in only defecation frequency . The difference was 3.3 ( 95 % CI : 0.41 , 6.19 , p = 0.03 ) . Conclusion Moxibustion treatment appears safe , but showed no positive effect on constipation . The effectiveness of moxibustion treatment may depend on the syndrome pattern , and further long-term studies with a larger number of subjects are warranted . Trial registration Clinical Research Information Service , Background Asthma is a major health problem and has significant mortality around the world . Although the symptoms can be controlled by drug treatment in most patients , effective low-risk , non-drug strategies could constitute a significant advance in asthma management . An increasing number of patients with asthma are attracted by acupuncture and moxibustion . Therefore , it is of importance that scientific evidence about the efficacy of this type of therapy is regarded . Our past research es suggested heat-sensitive moxibustion might be effective in treatment of asthma . Our objective is to investigate the effectiveness of  heat-sensitive moxibustion  compared with conventional drug treatment . Methods / Design This study is comprised of a multi-centre ( 12 centers in China ) , r and omized , controlled trial with two parallel arms ( A : heat-sensitive moxibustion ; B : conventional drug ) . Group A selects heat- sensitive acupoints from the rectangle region which consist of two outer lateral lines of dorsal Bladder Meridian of Foot-Taiyang , and two horizontal lines of BL13(Fei Shu ) and BL17 ( Ge Shu);6 inch outer the first and second rib gap of anterior chest . Group B treats with fluticasone/salmeterol ( seretide ) . The outcome measures will be assessed over a 3-month period before each clinic visit at days 15 , 30 , 60 , and 90 . Follow-up visit will be at 3 , 6 months after the last treatment session . Adverse event information will be collected at each clinic visit . Discussion This trial will utilize high quality trial method ologies in accordance with CONSORT guidelines . It may provide evidence for the effectiveness of heat-sensitive moxibustion as a treatment for chronic moderate persistent asthma . Moreover , the result may propose a new type moxibustion to control asthma . Trial Registration The trial is registered at Chinese Clinical Trials Registry : OBJECTIVE To probe the therapeutic effect and safety of ginger-salt-partitioned moxibustion on urination disorders poststroke . METHODS Eighty-two cases of cerebral apoplexy , including cerebral infa rct ion and cerebral hemorrhage , with urination disorders induced by neurogenic bladder at restoration stage were r and omly divided into a treatment group treated with ginger-salt-partitioned moxibustion at Shenque ( CV 8) and routine acupuncture , and a control group treated with routine acupuncture .  Thirty-nine cases in the treatment group and 36 cases in the control group completed all treatments . The treatment was given 5 times each week and the therapeutic effects were observed after treatment of 3 consecutive weeks . RESULTS Ginger-salt-partitioned moxibustion in improvement of mean urination times of each day , mean times to be asked to awaken for the nursing personnel at night , mean times of urgent urinary incontinence at day for the patient , cases-times of urinary incontinence of the patient at night , and increasing degree of urinary incontinence was better than the control group ( P<0.01 , P<0.05 ) . CONCLUSION Ginger-salt-partitioned moxibustion is a safe and effective therapy for urination disorders poststroke Background Though moxibustion is frequently used to treat primary dysmenorrhea in China , relevant evidence supporting its effectiveness is still scanty . Methods This study was a pragmatic r and omized , conventional drug controlled , open-labeled clinical trial . After initial screen , 152 eligible participants were averagely r and omized to receive two different treatment strategies : Moxibustion and conventional drugs . Participants and practitioners were not blinded in this study . The duration of each treatment was 3 months . The primary outcome was pain relief measured by the Visual Analogue Scale . The menstrual pain severity was recorded in a menstrual pain diary . Results 152 eligible patients were included but only 133 of them eventually completed the whole treatment course . The results showed that the menstrual pain intensity in experimental group and control group was reduced from 6.38±1.28 and 6.41±1.29 , respectively , at baseline , to 2.54±1.41 and 2.47±1.29 after treatment . The pain reduction was not significantly different between these two groups ( P = 0.76 ) , however ; the pain intensity was significantly reduced relative to baseline for each group ( P<0.01 ) . Three months after treatment , the effectiveness of moxibustion sustained and started to be superior to the drug ’s effect ( -0.87 , 95%CI -1.32 to -0.42 , P<0.01 ) . Secondary outcome analyses showed that moxibustion  was as effective as drugs in alleviating menstrual pain-related symptoms . The serum levels of pain mediators , such as PGF2α , OT , vWF , β-EP , PGE2 , were significantly improved after treatment in both groups ( P<0.05 ) . No adverse events were reported in this trial . Conclusions Both moxibustion and conventional drug showed desirable merits in managing menstrual pain , given their treatment effects and economic costs . This study as a pragmatic trial only demonstrates the effectiveness , not the efficacy , of moxibustion for menstrual pain . It ca n’t rule out the effect of psychological factors during treatment process , because no blind procedure or sham control was used due to availability . In clinical practice , moxibustion should be used at the discretion of patients and their physicians . Trial registration ClinialTrials.gov Moxibustion has been used to treat various types of disease . However , there is still insufficient evidence regarding its effectiveness . This study was performed to summarize and evaluate the effectiveness of moxibustion . A search was performed for all r and omized controlled trials in PubMed between January 1998 and July 2008 with no language restriction . The results yielded 47 trials in which six moxibustion types were applied to 36 diseases ranging from breech presentation to digestive disorders .  Moxibustion was compared to three types of control group : general care , Oriental medical therapies or waiting list . Moxibustion was superior to the control in 14 out of 54 control groups in 46 studies . There were no significant differences among groups in 7 studies , and the outcome direction was not determined in 33 studies . Seven studies were included in a meta- analysis . Moxibustion was more effective than medication in two ulcerative colitis studies ( relative risk ( 95 % CI ) , 2.20 ( 1.37 , 3.52 ) , P = .001 , I 2 = 0 % ) . Overall , our results did not support the effectiveness of moxibustion  in specific diseases due to the limited number and low quality of the studies and inadequate use of controls . In order to provide appropriate evidence regarding the effectiveness of moxibustion , more rigorous clinical trials using appropriate controls are warranted Abstract Background : Cancer-related fatigue ( CRF ) is the most common and distressing symptom associated with cancer treatment that breast cancer survivors ( BCS ) experience . We previously found that laser moxibustion may be efficacious for CRF . The primary aim of this study is to determine the specific efficacy of 10.6 μm infrared laser moxibustion on CRF . The secondary aim is to evaluate the effect of infrared laser moxibustion on co-existing symptoms that BCS experience . Methods : We will conduct a r and omized , sham-controlled , three-arm trial of infrared laser moxibustion ( ILM ) against sham ILM ( SILM ) and waitlist control ( WLC )  among BCS with moderate to severe fatigue . The two intervention groups will receive either real or sham infrared laser moxibustion on four acupoints ( i.e. , ST36 [ bilateral ] , CV4 , and CV6 ) for 20 minutes each session for 6 weeks ( twice per week ) . The primary endpoint is the change in fatigue score from Baseline to Week 6 as measured by the Chinese version of the Brief Fatigue Inventory ( BFI-C ) . Our secondary aim is to compare the severity of co-morbidities ( e.g. , depression , insomnia , and pain ) among the 3 groups . Discussion : The results of our trial will establish evidence for the efficacy of infrared laser moxibustion for CRF , a very common and challenging symptom . Trial registration number : NCT03553355 Objective The aim of this study was to investigate the difference of efficacy between conventional moxibustion ( CM ) and smoke-free moxibustion ( SM ) for patients with osteoarthritis of the knee ( KOA ) . Methods This is a multicentre , r and omized , single blinded , parallel-group clinical trial . Patients with KOA were r and omly allocated to CM group ( 69 ) and SM group ( 69 ) in 7 hospitals of China .  Moxibustion treatment in 12 sessions over 4 weeks was administrated at 3 acupuncture points ( EX-LE4 , ST35 , and ST36 ) . Patients completed st and ard question naires at baseline and after 2 weeks , 4 weeks , 8 weeks , and 12 weeks . The primary outcome was the Western Ontario and McMaster Universities Osteoarthritis Index ( WOMAC ) from the baseline to 4 weeks . The secondary outcomes include Visual Analogue Scale ( VAS ) and Patient Global Assessment score ( PGA ) . Results Analyses showed that the WOMAC score improved in pain ( 95 % CI,-0.1[-1.2 to 0.9 ] , p=0.76 ) , stiffness ( 95 % CI,-0.1 [ -0.5 to 0.3 ] , p=0.71 ) , and function ( 95 % CI , 2.2 [ -1.3 to 5.8 ] , p=0.22 ) compared between the two groups at 4 weeks , as well as the VAS score ( 95 % CI,0.1 [ -0.3 to 0.6 ] , p=0.60 ) . Similar results presented at 8 and 12 weeks . No statistically significant difference was observed between CM and SM groups for outcome measurements . Conclusions It suggested that smoke generated during moxibustion treatment does not affect the efficacy of moxibustion in the treatment of KOA , which should be taken into account to be removed for the sake of reducing environmental pollution or moxa smoke exposure of acupuncturists or patients . This trial is registered with Clinical Trials.gov , NCT02772055 PURPOSE To determine the effectiveness of acupuncture for the management of hot flashes in women with breast cancer . PATIENTS AND METHODS We conducted a pragmatic , r and omized controlled trial comparing acupuncture plus enhanced self-care versus enhanced self-care alone . A total of 190 women with breast cancer were r and omly assigned . R and om assignment was performed with stratification for hormonal therapy ; the allocation ratio was 1:1 . Both groups received a booklet with information about climacteric syndrome and its management to be followed for at least 12 weeks . In addition , the acupuncture group received 10 traditional acupuncture treatment sessions involving needling of predefined acupoints . The primary outcome was hot flash score at the end of treatment ( week 12 ) , calculated as the frequency multiplied by the average severity of hot flashes . The secondary outcomes were climacteric symptoms and quality of life , measured by the Greene Climacteric and Menopause Quality of Life scales . Health outcomes were measured for up to 6 months after treatment . Expectation and satisfaction of treatment effect and safety were also evaluated . We used intention-to-treat analyses . RESULTS Of the participants , 105 were r and omly assigned to enhanced self-care and 85 to acupuncture plus enhanced self-care . Acupuncture plus enhanced self-care was associated with a significantly lower hot flash score than enhanced self-care at the end of treatment ( P < .001 ) and at 3- and 6-month post-treatment follow-up visits ( P = .0028 and .001 , respectively ) . Acupuncture was also associated with fewer climacteric symptoms and higher quality of life in the vasomotor , physical , and psychosocial dimensions ( P < .05 ) . CONCLUSION Acupuncture in association with enhanced self-care is an effective integrative intervention for managing hot flashes and improving quality of life in women with breast cancer OBJECTIVE To evaluate the efficacy and safety of acupuncture and moxibustion in the treatment of post-stroke depression ( PSD ) by regulating the liver and strengthening the root prescription . METHODS In light of the r and om controlled trial principle , 123 cases were r and omized into an acupuncture-moxibustion group ( 42 cases ) , a medication group ( 40 cases ) and an acupuncture + medication group ( 41 cases ) . In the acupuncture-moxibustion group , the therapy of regulating the liver and strengthening the root was applied . Acupuncture was given at Hegu ( LI 4 ) , Taichong ( LR 3 ) , Baihui ( GV 20 , Yintang ( GV 29 ) , etc . The granule moxibustion was applied at Zhongwan ( CV 12 ) , Xiawan ( CV 10 ) , Guanyuan ( CV 4 ) and Qihai ( CV 6 ) . The treatment was given once a day and stopped in weekend . In the medication group , paroxetine hydrochloride tablets were prescribed for oral administration , 20 mg each day after breakfast . In the acupuncture + medication group , the therapies were adopted as the acupuncture-moxibustion group and the medication group . In the 2nd and 4th week of treatment , HAMD was used as the primary index and Barthel index as the secondary one for the efficacy assessment in the three groups respectively . The spleen and stomach syndrome scale of TCM was used for the assessment of TCM syndrome efficacy . Treatment emergent symptom scale ( TESS ) was applied for the safety assessment . RESULTS In the 4th week of treatment , the markedly effective rates were 69.0 % ( 29/42 ) , 65.0 % ( 26/40 ) and 70.7 % ( 29/41 ) in the acupuncture-moxibustion group , the medication group and the acupuncture + medication group respectively . The efficacies of anti-depression were similar in comparison among groups ( P > 0.05 ) . In the 2nd week of treatment , the improvement of HAMD score was significant in the acupuncture + medication group as compared with that before treatment and in comparison with the medication group ( P < 0.05 , P < 0.01 ) . As for improving Barthel index , reducing the spleen and stomach symptom score of TCM and decreasing the score of TESS , the results in the acupuncture-moxibustion group and the acupuncture + medication group were superior to those in the medication group ( P < 0.05 , P < 0.01 ) . CONCLUSION The therapy of acupuncture and moxibustion with regulating the liver and strengthening the root achieves the definite efficacy of anti-depression and presents the quite high safety in treatment OBJECTIVE To observe the clinical effect of moxibustion of different acupoints undergoing heat-sensitive state and resting state in the treatment of knee osteoarthritis ( KOA ) patients . METHODS A total of 60 cases of KOA patients were enrolled in the present trial . They were divided into heat-sensitive moxibustion ( heat-sensitive ) group and non-sensitive moxibustion group ( resting group ) . Moxibustion was applied to Neixiyan ( EX-LE 4 ) , Waixiyan ( i.e. Dubi , ST 35 ) and Heding ( EX-LE 2 ) for about 45 min , once daily for 20 days . The heat-sensitive state was evaluated according to the patient 's feeling . After moxibustion stimulation at the acupoint area , if the patient feels the heat penetrating from the skin surface to the deep tissue , or/ and extending peripherally around the moxibustion site , or/ and transmitting toward a certain direction , it is considered to be heat sensitization state . The therapeutic effect was evaluated by using visual analogue scale ( VAS ) for pain severity changes and by Guiding Principles for Clinical Trials of New Drugs of Chinese Materia Medica for evaluating functional activity of the knee-joint . RESULTS After 20 sessions of treatment and after a half year 's follow-up , the total integrated scores of VAS in the heat-sensitive group were all lower than those of the resting group ( P < 0.01 ) . Following 20 sessions of treatment , of the two 30 KOA patients in the heat-sensitive group and resting group , 14 ( 46.67 % ) and 5 ( 16.67 % ) experienced a marked improvement , 10 ( 33.33 % ) and 9 ( 30.00 % ) were effective , 6 ( 20.00 % ) and 16 ( 53.33 % ) were invalid , with the effective rates being 80.00 % and 46.67 , respectively . Half-year 's follow-up showed that the effective rates of the heat-sensitive group and resting group were 79.17 % ( 19/24 ) and 42.86 % ( 6/14 ) , respectively , suggesting a better therapeutic effect of heat-sensitive moxibustion . CONCLUSION The clinical n effect of heat-sensitive moxibustion is significantly superior to that of non-sensitive moxibustion in the treatment of KOA patients , being worthy of clinical application
Conclusion The evidence is limited to suggest moxibustion is an effective supportive cancer care in nausea and vomiting .
Background Moxibustion is a traditional Chinese method that uses the heat generated by burning herbal preparations containing Artemisia vulgaris to stimulate acupuncture points .
Considering moxibustion is closely related to acupuncture , it seems pertinent to evaluate the effectiveness of moxibustion as a treatment of symptoms of cancer .
The objective of this review was to systematic ally assess the effectiveness of moxibustion for supportive cancer care .