Efficacy of standard (SLA) and modified sandblasted and acid-etched (SLActive) dental implants in promoting immediate and/or early occlusal loading protocols: a systematic review of prospective studies. Prospective 10-year cohort study based on a randomized controlled trial (RCT) on implant-supported full-arch maxillary prostheses. Part 1: sandblasted and acid-etched implants and mucosal tissue. Early loading of sandblasted and acid-etched (SLA) implants: a prospective split-mouth comparative study. Early loading of nonsubmerged titanium implants with a chemically modified sand-blasted and acid-etched surface: 6-month results of a prospective case series study in the posterior mandible focusing on peri-implant crestal bone changes and implant stability quotient (ISQ) values. Early loading (2 or 6 weeks) of sandblasted and acid-etched (SLA) ITI implants in the posterior mandible. A 1-year randomized controlled clinical trial. Early loading at 21 days of non-submerged titanium implants with a chemically modified sandblasted and acid-etched surface: 3-year results of a prospective study in the posterior mandible. Early loading of sandblasted, acid-etched implants in the posterior maxilla and mandible: a 1-year follow-up report from a multicenter 3-year prospective study. Enhanced implant stability with a chemically modified SLA surface: a randomized pilot study. Early loading of nonsubmerged titanium implants with a sandblasted and acid-etched (SLA) surface: 3-year results of a prospective study in partially edentulous patients. Immediate restoration of nonsubmerged titanium implants with a sandblasted and acid-etched surface: five-year results of a prospective case series study using clinical and radiographic data. Early loading of non-submerged titanium implants with a sandblasted and acid-etched surface. 5-year results of a prospective study in partially edentulous patients. Early loading of sandblasted and acid-etched titanium implants in the edentulous mandible: a prospective 5-year study. A randomized, 12-month controlled trial to evaluate non-inferiority of early compared to conventional loading of modSLA implants in single tooth gaps Immediate vs. early loading of SLA implants in the posterior mandible: 5-year results of randomized controlled clinical trial. Immediate and early non-occlusal loading of Straumann implants with a chemically modified surface (SLActive) in the posterior mandible and maxilla: interim results from a prospective multicenter randomized-controlled study. Early loading of sandblasted and acid-etched implants: a randomized-controlled double-blind split-mouth study. Five-year results. Preliminary 3-dimensional surface texture measurement and early loading results with a microtextured implant surface.
OBJECTIVE To assess the survival percentage , clinical and radiographic outcomes of s and blasted and acid-etched ( SLA ) dental implants  and its modified surface ( SLActive ) in protocol s involving immediate and early occlusal loading . METHODS MEDLINE , EMBASE and the Cochrane Oral Health Group 's Trials Register CENTRAL were search ed in duplicate up to , and including , June 2013 to include r and omised controlled trials ( RCTs ) and prospect i ve observational studies of at least 6-month duration published in all language s. Studies limited to patients treated with SLA and /or SLActive implants involving a treatment protocol describing immediate and early loading of these implants were eligible for inclusion . Data on clinical and /or radiographic outcomes following implant placement were considered for inclusion . RESULTS Of the 447 potentially eligible publications identified by the search strategy , seven RCTs comprising a total of 853 implants ( 8 % titanium plasma-sprayed , 41.5 % SLA and 50.5 % SLActive ) and 12 prospect i ve observational studies including 1394 SLA and 145 SLActive implants  were included in this review . According to the Cochrane Collaboration 's tool for assessing risk of bias , one of the studies was considered to be at a low risk of bias , whereas the remaining studies were considered to be at an unclear risk . Regarding the observational studies , all of them presented a medium method ological quality based on the Modified Newcastle-Ottawa scale . There were no significant differences reported in the studies in relation to implant loss or clinical parameters between the immediate/early loading and delayed loading protocol s. Overall , 95 % of SLA and 97 % of SLActive implants  still survive at the end of follow-up . CONCLUSIONS Despite of the positive findings achieved by the included studies , few RCTs were available for analysis for SLActive implants . Study heterogeneity , scarcity of data and the lack of pooled estimates represent a limitation between studies ' comparisons and should be considered when interpreting the present findings BACKGROUND There have been very few long-term controlled studies ( i.e. , over 5 years duration ) focusing on marginal conditions for implants with a s and blasted , large grit , and acid-etched ( SLA ) surface . PURPOSE To evaluate and report 10-year data on outcomes of  implants with an SLA surface placed in the edentulous maxilla . MATERIAL S AND METHODS In a r and omized controlled trial ( RCT ) cohort of 24 patients , the outcomes of implants with an SLA surface were registered . The RCT cohort has previously been reported after 1 year , 3 years , and 5 years of loading . RESULTS One patient dropped out of the study prior to the 10-year control . Of the 23 remaining patients , the implant survival rate was 95.1 % . If implants of unknown status were also considered lost , that is , one drop-out patient with three implants for whom no information could be obtained , the implant survival rate was 93 % . The mean marginal bone loss from baseline ( 139 implants ) to 10 years ( 102 implants ) was 1.07 mm ( st and ard deviation 0.98 ) . One implant out of 102 available for radiographic examination according to the original protocol showed a bone loss exceeding 4 mm . Of the 84 implants available for clinical examination , none showed a Plaque Index or sulcus bleeding index of 3 . The mean implant stability quotient was significantly higher for mesial-distal versus buccal-palatal measurements . CONCLUSION The implant survival was 95.1 % . The mean value of bone loss after 10 years was 1.07 mm . Peri-implantitis were noted at the 5-year follow-up for one patient with a previous history of periodontitis ; this patient did not attend the 10-year follow-up . This study shows that s and blasted and acid-etched implants offers predictable long-term results as support for full-arch maxillary prostheses S and blasted and acid-etched ( SLA ) implants were recently introduced to reduce the healing period between surgery and prosthesis . In this split-mouth study , SLA implants were compared to titanium plasma-sprayed ( TPS ) implants under loaded conditions one year after placement in 32 healthy patients , with comparable bilateral edentulous sites and no discrepancies in the opposing dentition . The surgical procedure was performed by the same operator and was identical at 68 SLA ( test ) and 68 TPS ( control ) sites . Tapping was never performed and primary stability was always achieved . Abutment connection was carried out at 35 Ncm 6 weeks postsurgery for test sites and 12 weeks for the controls , by the same dentist blind to the type of surface of the implant . In 4 of the 68 test sites the implant rotated slightly , patients reported minor pain and connection was not completed . Provisional restoration was fabricated and a new tightening was performed after six weeks . Similar gold-ceramic restorations were cemented on the same type of solid abutments on both sites . No implant was lost . Clinical measures and radiographic changes were recorded by the same operator , blind to the type of surface of the implant , 1 year post surgery . No significant differences were found with respect to presence of plaque ( 24 % vs. 27 % ) , bleeding on probing ( 24 % vs. 31 % ) , mean pocket depth ( 3.3 mm vs. 2.9 mm ) or mean marginal bone loss ( 0.65 mm vs. 0.77 mm ) . The results suggest that SLA implants are suitable for early loading at 6 weeks . Limited implant spinning may occasionally be found but , if properly h and led , it produces no detrimental effect on the clinical outcome PURPOSE The aim of this prospect i ve case series study was to evaluate the short-term success rates of  titanium screw-type implants  with a chemically modified s and -blasted and acid-etched ( mod SLA ) surface after 3 weeks of healing . MATERIAL AND METHODS A total of 56 implants were inserted in the posterior m and ible of 40 partially edentulous patients exhibiting bone densities of class I to III . After a healing period of 3 weeks , all implants were functionally loaded with a screw-retained crown or fixed dental prosthesis . The patients were recalled at weeks 4 , 7 , 12 , and 26 for monitoring and assessment of clinical and radiological parameters , including implant stability quotient ( ISQ ) measurements . RESULTS None of the implants failed to integrate . However , two implants were considered " spinners " at day 21 and left unloaded for an extended period . Therefore , 96.4 % of the inserted implants were loaded according to the protocol tested . All 56 implants including the " spinners " showed favorable clinical and radiographic findings at the 6-month follow-up examination . The ISQ values increased steadily throughout the follow-up period . At the time of implant placement , the range of ISQ values exhibited a mean of 74.33 , and by week 26 , a mean value of 83.82 was recorded . Based on strict criteria , all 56 implants were considered successfully integrated , result ing in a 6-month survival and success rate of 100.0 % . CONCLUSION This prospect i ve study using an early-loading protocol after 3 weeks of healing demonstrated that titanium implants with the modified SLA surface can achieve and maintain successful tissue integration over a period of at least 6 months . The ISQ method seems feasible to monitor implant stability during the initial wound-healing period UNLABELLED The aim of this 1-year prospect i ve controlled clinical trial was to evaluate the effect of early loading of ITI solid screw titanium implants with a s and blasted and acid-etched ( SLA ) surface on clinical and radiographic parameters . MATERIAL AND METHODS Twenty-seven consecutively admitted patients presenting bilateral edentulous posterior m and ibular areas and in need of prosthetic reconstruction were recruited . Sixty-seven ITI st and ard solid screw implants with an SLA surface , a diameter of 4.1 mm and a length of 8 , 10 or 12 mm were installed bilaterally in molar and premolar areas according to a one-stage surgical protocol . One week ( test ) and 5 weeks ( control ) after implant placement , solid ITI prosthetic abutments were connected using a torque of 35 N cm . No provisional restoration was fabricated . Two weeks ( test ) and 6 weeks ( control ) after implant placement , porcelain-fused-to-metal single-tooth crowns were cemented . Clinical measurements were obtained at day 0 and 2 , 6 , 12 , 24 and 52 weeks thereafter . Periapical radiographs were taken immediately after implant placement , after 6 weeks and at the 1-year examination . RESULTS After 1 year , implant survival was 100 % . Two test and one control implants rotated at the time of abutment connection and were left unloaded for 12 additional weeks . At the 1-year examination , no statistically significant differences were found between the test and control sites with respect to pocket probing depths ( 2.6 mm + /- 0.5 vs. 2.7 mm + /- 0.5 ) , mean clinical attachment levels ( 3.1 mm + /- 0.4 vs. 3.2 mm + /- 0.5 ) , mean percentages of sites bleeding on probing ( 9.7 % vs. 8.3 % ) , mean widths of keratinized mucosa ( 1.8 mm + /- 0.4 vs. 1.9 mm + /- 0.5 ) , mean PerioTest values ( -1.4 PTV + /- 0.9 vs. -1.6 PTV + /- 0.8 ) or mean crestal bone loss measurements ( 0.57 mm + /- 0.49 vs. 0.72 mm + /- 0.50 ) . CONCLUSION Based on these results , loading of titanium implants with an SLA surface as early as 2 weeks did not appear to jeopardize the osseointegration healing process in the posterior m and ible . Furthermore , implants rotating at 35 N cm , if left unloaded for additional 12 weeks , did not negatively affect clinical and radiographic outcomes BACKGROUND This study evaluates 3-year success rates of  titanium screw-type implants with a chemically modified s and blasted and acid-etched surface ( mod SLA ) , which were functionally loaded after 3 weeks of healing . METHODS A total of 56 implants , inserted in the posterior m and ibles of 39 partially edentulous patients , underwent undisturbed healing for 3 weeks . At day 21 , the implants were fully loaded with provisional crowns . Definitive metal ceramic restorations were fabricated after 6 months of healing . Clinical measurements regarding soft tissue parameters and radiographs were obtained at different time points up to 36 months after implant placement . The soft tissue and radiographic parameters for the mod SLA implants after 3 years in function were compared to a historic control group of implants with an SLA surface using an early loading protocol after 6 weeks . RESULTS None of the implants failed to integrate . However , two implants were considered " spinners " at day 21 and were left unloaded for an extended period . Therefore , 96.4 % of the inserted implants were loaded according to the protocol tested . All 56 implants , including the " spinners , " showed favorable clinical and radiographic findings at the 3-year follow-up examination . All 56 implants were considered successfully integrated , result ing in a 3-year survival and success rate of 100 % . Dental implants with a mod SLA surface demonstrated statistically significant differences for probing depths and clinical attachment level values compared to the historic control group , with the mod SLA surface implants having overall lower probing depths and clinical attachment level scores . CONCLUSION This prospect i ve study using an early loading protocol demonstrates that titanium implants with the mod SLA surface can achieve and maintain successful tissue integration over a period of 3 years PURPOSE The aim of the present study was to evaluate the concept of an immediate loading protocol in the posterior maxilla and m and ible through analysis of implant survival at 1 year . MATERIAL S AND METHODS One year follow-up data of a multicenter study are reported . Eighty-two ITI s and blasted , acid-etched ( SLA ) implants in 40 patients were loaded between 0 and 11 days after implant placement ( mean 4.3 + /- 2.8 days ) . The restorations consisted of either 2 splinted crowns or a 3-unit fixed prosthesis . All restorations were put into full functional occlusion . Periapical radiographs were evaluated for changes in crestal bone level from baseline to 1 year postloading . Primary stability of the implants was checked initially and before the fitting of the definitive prosthesis . The restorations were evaluated by the practitioners for retention , stability , and esthetics . RESULTS Three patients ' implants were not loaded because of lack of primary stability , and a fourth patient was excluded from the study because of a protocol violation ( more than 4 implants were used ) . All 4 patients were successfully treated outside the protocol . The overall survival rate of the remaining implants at 1 year was 98.8 % . The mean bone loss at 1 year was 0.52 + /- 0.98 mm , which is within the reported limits of less than 1 mm ( range 0.4 to 1.4 mm ) loss in the first year . DISCUSSION AND CONCLUSION The early results from this study indicate that early and immediate loading of 2 implants in the posterior maxilla and m and ible may be suitable in selected patients . On the basis of 1 year of observation , the results appear similar to those achieved with a delayed procedure PURPOSE Chemical modification to a s and blasted , large-grit , acid-etched ( SLA ) implant surface has been shown to enhance the rate of osseointegration . The goal of the present study was to examine changes in stability for implants with a chemically modified SLA surface and to compare their outcomes to those of control implants . MATERIAL S AND METHODS A r and omized controlled trial was conducted with 31 patients . Each patient received 2 implants with the same physical properties but with surfaces that were chemically different . The control implants had a st and ard SLA surface , while the test implants had a chemically modified surface . Resonance frequency analysis was assessed weekly over the first 6 weeks following implant placement . RESULTS All implants proved clinical ly successful , allowing for restoration . Most implants were placed in the m and ible ( 50 of 62 ) . A shift in implant stability from decreasing stability to increasing stability ( P < .001 ) , occurred after 2 weeks for the test implants and after 4 weeks for the control implants . CONCLUSION The findings from this pilot study provide clinical support for the potential for chemical modification of the SLA surface to alter biologic events during the osseointegration process and demonstrate levels of short-term clinical success similar to those observed for implants with an SLA surface PURPOSE The aim of this study was to evaluate the success rate of ITI implants with the SLA surface that were loaded after 6 weeks of healing . MATERIAL S AND METHODS In this prospect i ve cohort study , a total of 104 implants were placed in posterior sites of 51 partially edentulous patients exhibiting bone densities of Class 1 , 2 , or 3 . After a healing period of 6 weeks , all implants were functionally loaded with cemented crowns or fixed partial dentures . The patients were recalled at 3 , 12 , 24 , and 36 months for clinical and radiographic examination . RESULTS One implant failed to integrate during healing , and 1 implant was lost to follow-up and considered a dropout . The remaining 102 implants showed favorable clinical and radiographic findings and were considered successfully integrated at the 3-year examination . This result ed in a 3-year success rate of 99.03 % . DISCUSSION The peri-implant soft tissues were stable over time , as evidence d by no changes in the mean probing depths and the mean attachment levels during the follow-up period . None of the radiographs exhibited signs of continuous peri-implant radiolucency , which confirmed ankylotic stability of all 102 implants . The radiographic evaluation of the bone level at the implant indicated stability of the bone crest levels . CONCLUSION The results of this prospect i ve study demonstrated that early loading of ITI implants with the SLA surface after an unloaded healing period of 6 weeks provided successful tissue integration with high predictability , and that successful tissue integration was well maintained up to 3 years of follow-up in this study population The aim of this study was to evaluate the survival and success rates of immediately restored implants with s and blasted , large-grit , acid-etched ( SLA ) surfaces over a period of 5 years . Twenty patients ( mean age , 47.3 years ) received a total of 21 SLA wide-neck implants in healed m and ibular first molar sites after initial periodontal treatment . To be included in the study , the implants had to demonstrate primary stability with an insertion torque value of 35 Ncm . A provisional restoration was fabricated chairside and placed on the day of surgery . Definitive cemented restorations were inserted 8 weeks after surgery . Community Periodontal Index of Treatment Needs ( CPITN ) indices and the radiographic distance between the implant shoulder and the first visible bone-implant contact ( DIB ) were measured and compared over the study period . The initial mean CPITN was 3.24 , and decreased over the study period to 1.43 . At the postoperative radiographic examination , the mean DIB was 1.41 mm for the 21 implants , indicating that part of the machined neck of the implants was placed slightly below the osseous crest . The mean DIB value increased to 1.99 mm at the 5-year examination . This increase proved to be statistically significant ( P < .0001 ) . Between the baseline and 5-year examinations , the mean bone crest level loss was 0.58 mm . Success and survival rates of the 21 implants after 5 years of function were 100 % . This 5-year study confirms that immediate restoration of m and ibular molar wide-neck implants with good primary stability , as noted by insertion torque values of at least 35 Ncm , is a safe and predictable procedure OBJECTIVES The aim of this prospect i ve cohort study was to evaluate the success rate of titanium screw-type implants with the s and blasted and acid-etched ( SLA ) surface loaded early , after 6 weeks of healing . MATERIAL AND METHODS A total of 104 implants were inserted into posterior sites of 51 partially edentulous patients exhibiting bone densities of class I-III . After a healing period of 6 weeks , all implants were functionally loaded with cemented crowns or fixed partial dentures . The patients were recalled at 3 , 12 , 24 , 36 , 48 and 60 months for clinical and radiographic examination . RESULTS One implant failed to integrate during healing , and three implants were lost to follow-up and were considered drop-outs . The remaining 100 implants showed favorable clinical and radiographic findings at the 5-year examination . The peri-implant soft tissues were stable over time ; the mean probing depths and mean attachment levels did not change during the follow-up period . None of the radiographs exhibited signs of continuous peri-implant radiolucency , which confirmed ankylotic stability for all 100 implants . The measurement of the bone crest levels ( DIB values ) indicated stability as well . Based on strict success criteria , all 100 implants were considered successfully integrated , result ing in a 5-year success rate of 99 % . CONCLUSION This prospect i ve study using an early loading protocol with 6 weeks of healing demonstrated that titanium implants with the SLA surface can achieve and maintain successful tissue integration with high predictability for at least 5 years of follow-up in selected patients and sites PURPOSE The aim of this prospect i ve cohort study was to determine the 5-year implant survival and success rates associated with early loading ( 6 weeks after nonsubmerged placement ) of s and blasted and acid-etched ( SLA ) Straumann implants in the edentulous m and ible . A secondary objective was to determine the peri-implant tissue response and measure alterations in peri-implant crestal bone levels . MATERIAL S AND METHODS SLA implants were placed and primarily loaded 6 weeks later with 35 Ncm during abutment placement . The peri-implant bone and mucosal conditions of the participants were monitored radiographically and clinical ly over a 5-year period . RESULTS Fourteen patients received 60 implants . Thirteen patients and 54 implants were examined at the 5-year appointment . Two of 60 implants failed during the healing period , and four implants were lost during follow-up and considered as dropouts . The remaining implants showed favorable clinical and radiographic findings and were considered successfully integrated at the 5-year examination . The mean loss of crestal bone height after 5 years was 0.77 mm ( SEM 0.09 ) . This result ed in a 5-year cumulative success rate of 96.7 % . CONCLUSION In this prospect i ve study , the early loading of  Straumann implants with the SLA surface in the edentulous m and ible after a healing time of 6 weeks provided successful osseointegration with high predictability . Successful integration was maintained for 5 years Background The aim of the study was to evaluate whether early loading of implants with a chemically modified s and blasted , large-grit , acid-etched ( SLA ) ( SLActive ® ) surface was non-inferior to conventional loading in terms of change in crestal bone level . Methods This was a r and omized , controlled , multicenter study . Patients requiring single-tooth rehabilitation in the posterior maxilla or m and ible received implants and were r and omized to receive a provisional restoration in occlusal load after 25 ± 3 days ( early loading ) or after 13 ± 1 weeks ( conventional loading ) . The primary endpoint was change in crestal bone level between implant placement ( baseline ) and 6 months . Secondary endpoints included change in crestal bone level between baseline and 12 months , implant survival and success rates , and patient satisfaction . Results Of the 84 patients enrolled , 78 received implants  and were r and omized onto the  early loading ( 41 patients ) and  conventional loading ( 37 patients ) groups . The mean change in crestal bone level between baseline and 6 months was 0.56 ± 0.58 and 0.51 ± 0.62 mm for early and conventional loading , respectively ; at 12 months , the mean change was 0.76 ± 0.60 and 0.73 ± 0.77 mm , respectively . Implant survival and success at 12 months were 100 % for both groups . Patient satisfaction was similar between the groups , except that more patients in the early loading group were satisfied or highly satisfied with the time taken for fitting . Conclusion The study demonstrated that early implant loading was non-inferior to conventional implant loading in terms of crestal bone level change in a Japanese patient population in short follow-up period and single tooth gaps in molar regions OBJECTIVES The aim of this study was to compare clinical results of immediate and early loading ( EL ) self-tapping implants placed in posterior m and ibles . MATERIAL AND METHODS Twelve patients with bilateral edentulous posterior m and ibular were r and omly assigned to treatment either with immediate ( test ) or early loaded implants ( control ) . Seventy-two self-tapping implants  with SLA surface ( Ø 4 , 1/4 , 8 mm ; length 8 and 10 mm ) were analyzed in this study . Test implants ( 36 ) were loaded on the day of surgery and control implants 6 weeks later . The measuring of implant stability quotient ( ISQ ) was performed on 0 , 6th , 12th , and 52nd week after implant insertion . The bone resorption , modified plaque , and bleeding index were notified at 1 and 5 years later . RESULTS After 5 years , survival in the both groups was 100 % . The mean value of primary implant stability was 76.92 ± 0.79 ISQ . In the first 6 weeks , ISQ values significantly increased in the test group ( 77.92 ± 1.16 vs. 79.61 ± 0.90 ) as well as in the control group ( 7.92 ± 1.05 vs. 77.55 ± 0.99 ) . A significant longitudinal increase in ISQ value was recorded in test and control group . The differences between immediate and early loaded implants were statistically insignificant ( P > 0.05 ) . At the 5 years , no statistically significant differences were found between immediate and early loaded implants with respect to mean crestal bone loss measurements ( 0.4 ± 0.24 vs. 0.8 ± 0.15 mm ) , mean bleeding index ( 0.22 ± 0.11 vs. 0.25 ± 0.11 ) , and mean plaque index ( 0.17 ± 0.15 vs. 0.19 ± 0.20 ) . CONCLUSION Based on these results , the self-tapping implants inserted in posterior m and ible can provide adequate primary stability value as the main factor for immediate and EL protocol OBJECTIVE Immediate and early loading of dental implants can simplify treatment and increase overall patient satisfaction . The purpose of this 3-year prospect i ve r and omized-controlled multicenter study was to assess the differences in survival rates and bone level changes between immediately and early-loaded implants with a new chemically modified surface ( SLActive ) . This investigation shows interim results obtained after 5 months . MATERIAL AND METHODS Patients > or = 18 years of age missing at least one tooth in the posterior maxilla or m and ible were enrolled in the study . Following implant placement , patients received a temporary restoration either on the day of surgery ( immediate loading ) or 28 - 34 days after surgery ( early loading ) ; restorations consisted of single crowns or two to four unit fixed dental prostheses . Permanent restorations were placed 20 - 23 weeks following surgery . The primary efficacy variable was change in bone level ( assessed by st and ardized radiographs ) from baseline to 5 months ; secondary variables included implant survival and success rates . RESULTS A total of 266 patients were enrolled ( 118 males and 148 females ) , and a total of 383 implants were placed ( 197 and 186 in the immediate and early loading groups , respectively ) . Mean patient age was 46.3+/-12.8 years . After 5 months , implant survival rates were 98 % in the immediate group and 97 % in the early group . Mean bone level change from baseline was 0.81+/-0.89 mm in the immediate group and 0.56+/-0.73 mm in the early group ( P<0.05 ) . Statistical analysis revealed a significant center effect ( P<0.0001 ) and a significant treatment x center interaction ( P=0.008 ) . CONCLUSIONS The results suggested that Straumann implants with an SLActive can be used predictably in time-critical ( early or immediate ) loading treatment protocol s when appropriate patient selection criteria are observed . The mean bone level changes observed from baseline to 5 months ( 0.56 and 0.81 mm ) corresponded to physiological observations from other studies , i.e. , were not clinical ly significant . The presence of a significant center effect and treatment x center interaction indicated that the differences in bone level changes between the two groups were center dependent OBJECTIVES The aim of the present split-mouth study is to assess the peri-implant conditions around early-loaded s and blasted and acid-etched ( SLA ) implants , 5 years after abutment connection and to compare , in the same patients , the results obtained with a st and ard protocol using identical implants with a TPS surface . MATERIAL AND METHODS Surgical procedure was performed by the same operator and was identical at test ( SLA ) and control ( TPS ) sites , in 32 healthy patients . Abutment connection was carried out at 35 N cm 6 weeks postsurgery for test sites and 12 weeks for the controls . Patients were seen regularly , for control and professional cleaning . At 60 months , clinical measures and radiographic bone changes were recorded by the same operator , blind to the type of surface of the implant , on 27 patients , as five patients were lost to follow-up . RESULTS A total number of 106 implants were examined . No implant was lost . No significant differences were found with respect to the presence of plaque [ modified plaque index ( mPI ) 0.27+/-0.56 vs. 0.32+/-0.54 ] , bleeding on probing ( 29 % vs. 32 % ) , mean pocket depth ( 3.2+/-1 vs. 3.2+/-1 mm ) or mean marginal bone loss ( 0.32+/-1.04 vs. 0.44+/-1.12 mm ) between test and control . Four implants that presented ' spinning ' at the time of abutment connection presented no significant differences from the rest of the test sites . CONCLUSION The results of this prospect i ve study confirm that SLA implants , under defined conditions , are suitable for early loading at 6 weeks in both the m and ible and the maxilla . Limited implant spinning , occasionally found at abutment connection , produces no detrimental effect on the clinical outcome when properly h and led PURPOSE This investigation was conducted to obtain preliminary roughness data on a microtextured implant surface and to determine its ability to sustain a 1-stage surgical procedure and early full occlusal loading of single-tooth restorations in humans . MATERIAL S AND METHODS Three-dimensional ( 3D ) vertical scanning interferometry was conducted on sample s of the test surface ( MTX ) and 2 control surfaces ( Osseotite and s and blasted/acid-etched [ SLA ] ) . Test implants were also placed in vivo , restored with fully occluding single-tooth restorations ( n = 27 ) after 2 months of nonsubmerged healing , and clinical ly monitored for 48 months of follow-up . RESULTS Microtexture was relatively uniform on the test surface and more r and om and irregular on the control surfaces . MTX and Osseotite were similar in some roughness parameters , but the MTX surface had a greater number of micropits that were spaced closer together ( Stylus Y lambda q ) and with higher slope values ( Stylus Y delta q ) . Cumulative life table results were 100 % for all MTX implants placed in maxillary and m and ibular jaw locations , and no discernible marginal bone changes were observed . Overall implant success was 100 % after 4 years of clinical functioning . DISCUSSION The findings of this study appear promising but should be considered preliminary , because of the limitations in the number of locations measured on each product sample and the small number of implants clinical ly studied . CONCLUSION Within the scope of the present study , MTX implants exhibited a uniform micropitted surface , as well as 100 % survival and 100 % clinical success after nonsubmerged placement , early loading with single-tooth restorations at 2 months , and 48 months of clinical functioning . ( More than 50 references .
Despite of the positive findings achieved by the included studies , few RCTs were available for analysis for SLActive implants .
OBJECTIVE To assess the survival percentage , clinical and radiographic outcomes of s and blasted and acid-etched ( SLA ) dental implants  and its modified surface ( SLActive ) in protocol s involving immediate and early occlusal loading .