Shear bond strength comparison between two orthodontic adhesives and self-ligating and conventional brackets. Clinical performance of orthodontic brackets and adhesive systems: a randomized clinical trial. Shear bond strength of precoated orthodontic brackets: an in vivo study A Randomized Clinical Trial Comparing ‘One-Step’ and ‘Two-Step’ Orthodontic Bonding Systems Orthodontic in vivo bond strength: comparison with in vitro results. Comparison of bracket debonding force between two conventional resin adhesives and a resin-reinforced glass ionomer cement: an in vitro and in vivo study. Influence of force location in orthodontic shear bond strength testing. Microleakage under orthodontic brackets bonded with different adhesive systems Shear bond strength of a new fluoride-releasing orthodontic adhesive. A clinical trial comparing the failure rates of two orthodontic bonding systems. The influence of adding modified zirconium oxide-titanium dioxide nano-particles on mechanical properties of orthodontic adhesive: an in vitro study Comparison of bond strength of three adhesives: composite resin, hybrid GIC, and glass-filled GIC. Effect of changing a test parameter on the shear bond strength of orthodontic brackets. Comparison of bond strength between a conventional resin adhesive and a resin-modified glass ionomer adhesive: an in vitro and in vivo study. Influence of endodontic irrigants on bond strength of a self-etching adhesive. A Clinical Comparison of Bracket Bond Failures in Association with Direct and Indirect Bonding A 15-month evaluation of bond failures of orthodontic brackets bonded with direct versus indirect bonding technique: a clinical trial
OBJECTIVE To evaluate and compare the shear bond strengths of two adhesives using two types of brackets : a conventional and a self-ligating bracket system . MATERIAL S AND METHODS Sixty extracted human premolars were collected . The premolars were r and omly divided into three groups of 20 teeth . All three groups were direct bonded . Groups 1 and 2 used light-cured adhesive and primer ( Transbond XT ) with a conventional ( Orthos ) and a self-ligating bracket ( Damon 2 ) , respectively . Group 3 used a light-cured primer ( Orthosolo ) and a light-cured adhesive ( Blūgloo ) with a self-ligating bracket ( Damon 2 ) . The specimens were stored in distilled water at 37 degrees C for 40 + /- 2 hours , after which they were debonded and inspected for Adhesive Remnant Index ( ARI ) scoring . RESULTS The mean shear bond strength was 15.2 MPa for group 1 , 23.2 MPa for group 2 , and 24.8 MPa for group 3 . A one-way analysis of variance and post hoc Tukey test showed significant differences in bond strength ( P < .001 ) between group 1 and groups 2 and 3 but no significant difference ( P > .05 ) between groups 2 and 3 . A Weibull analysis demonstrated that all three groups provided sufficient bond strength with over 90 % survival rate at normal masticatory and orthodontic force levels . A Kruskal-Wallis test showed no significant difference ( P > .05 ) in ARI scores among all three groups . CONCLUSIONS All three groups demonstrated clinical ly acceptable bond strength . The Damon 2 self-ligating bracket exhibited satisfactory in vitro bond strength with both adhesive systems used The aim of the study was to evaluate and compare the clinical performance of adhesive precoated brackets ( APC ) with that of two types of uncoated bracket bases , Straight-Wire and Dyna-Lock , bonded using two types of orthodontic adhesives , Transbond XT , and Right-On .  Forty consecutive orthodontic patients entered the trial and 607 brackets were bonded . The incidence and site of first time bond failures were recorded over a period of 1 year . The time required for bonding was also recorded . The overall bond failure rate was 6.6 per cent . There were no significant differences between the failure rates of the five groups , or between the upper and lower arch . However , significantly more brackets failed on the left side than on the right . Premolar brackets were lost most often , whilst incisor brackets failed least . No association was found between bond failure and time elapsed since bonding . Bonding time was least with Right-On adhesive . There were no significant differences between bonding times using APC or Transbond . Results of the present study conflict with those of a previous ex vivo study by the authors , using the same material s and bonding technique . Suggested reasons for this are discussed Objective To evaluate the shear bond strength of precoated orthodontic brackets bonded with self-etching primer relative to that of noncoated conventionally-bonded brackets at two different time intervals . Methods Twenty-one subjects were selected for r and omized split-mouth bonding of two types of brackets to the maxillary arch . Half of the teeth had precoated brackets bonded using self-etching adhesive , and the other half had regular brackets bonded using Transbond XT adhesive . Nitinol wires were tied to the upper arch and were left until the time of debonding . The patients were r and omly divided into two groups : one debonded after one hour and the other debonded two weeks after the initial wire placement . The shear bond strength was directly recorded from the patients ’ mouths using an in vivo debonding device . Results There were no significant differences in shear bond strength between the precoated and conventional groups or within each group at different time intervals . There were significant differences between anterior and posterior teeth in both the precoated and conventional groups . Conclusion Pre-coated brackets bonded with self-etching adhesive have the same bonding strength as the conventionally bonded brackets Objective The primary objective of this prospect i ve clinical trial was to assess the clinical bond failure rates of orthodontic brackets bonded using a self-etching primer ( SEP ) , compared with brackets bonded using a conventional acid-etched technique with control adhesive ( Transbond ™ ) . A secondary aim was to investigate whether characteristics of the operator , patient or tooth bonded had any influence on bracket failure . Design Single-centre r and omized controlled clinical trial . Thirty-four patients were bonded , each being r and omly assigned to either the test or control adhesive . Setting NHS Hospital Orthodontic Department , Chester , UK . Subjects Orthodontic patients requiring fixed appliance treatment . Main outcome measures Bond failure . Main outcome results Failure rates over the initial 6-month period were 2.0 % ( Transbond ™ ) and 1.7 % ( SEP ) with no statistically significant difference between the two groups . Over the duration of the fixed appliance treatment , bond failure rates increased , but remained acceptable at 7.4 % ( TB ) and 7.0 % ( SEP ) , respectively . When operator , patient and tooth characteristics were analysed , only the bracket location was found to be significant . Maxillary brackets were more likely to fail than m and ibular brackets ( RR 0.47 % ; 95 % CI 0.22 , 1.03 ) . The failure rate for brackets in our study was low when compared with previous studies . Conclusions Both the acid-etched control and self-etching primer in combination with adhesive pre-coated brackets were successful for clinical bonding . Their combined failure rate was lower than that reported in similar trials The purpose of the present study was to test a new in vivo debonding device and compare in vivo bond strengths recorded by this device with in vitro bond strengths recorded by a universal testing machine such as the Instron . For the in vitro part of the study , 60 extracted premolar teeth were divided into 2 groups of 30 each . Both groups of 30 teeth had 3 M Unitek Victory Twin brackets , precoated with Transbond XT composite resin , bonded to them . Shear bond strength tests were carried out in vitro using the universal testing machine on one group of 30 teeth while the debonding device was used on the other group of 30 teeth . The mean shear bond strength of the group debonded using the universal machine was 11.02 MPa and that of the group debonded with the debonding device was 12.82 MPa . For the in vivo part of the study , 8 patients r and omly assigned to the research clinician from patients in The University of Alabama School of Dentistry , Department of Orthodontics , had a total of 60 premolar teeth bonded with 3 M Unitek Victory Twin brackets . Following comprehensive orthodontic treatment ( average time of 23 months ) , shear bond strength tests were carried out using the debonding device , which can measure debonding forces in vivo . The mean shear bond strength recorded in vivo was 5.47 MPa . Statistically significant differences were found between all 3 groups tested . The results appear to indicate that mean bond strengths recorded in vivo following comprehensive orthodontic treatment are significantly lower than bond strengths recorded in vitro The purpose of this study was to compare the debonding force of orthodontic brackets bonded with two conventional resin adhesives ( Resilience L3 and Light Bond ) and a resin-reinforced glass ionomer cement ( Fuji Ortho LC ) . For the in vitro part of the study , 80 extracted premolars were r and omly divided into four groups . In groups A and B , brackets were bonded to unetched enamel using Fuji Ortho LC cement in wet and dry conditions , respectively . In groups C and D , brackets were bonded to etched enamel using Resilience L3 and Light Bond , respectively .  Debonding force was determined using a servohydraulic testing machine at a crosshead speed of 1 mm/min . Data was analyzed using the ANOVA and Tukey-Kramer multiple comparison test at p<0.05 . A significant difference was found in debonding force between unetched Fuji Ortho LC and the two conventional resins . There was no significant difference between the two conventional resins or between unetched resin-reinforced glass ionomer in the wet and dry conditions . For the in vivo part of the study , 30 patients were r and omly assigned to one of the three bonding material groups . Bracket survival rates and distributions were obtained by following these patients for 1.2 years . Data was analyzed using the Kaplan-Meier product-limit estimates of survivorship function . Bond failure interface was determined using a modified adhesive remnant index ( ARI ) . These results showed no significant difference between survival rates and distributions among the three bonding material s with respect to the type of malocclusion , type of orthodontic treatment , or location of bracket . There were significant differences between survival distributions of males and females in the unetched Fuji Ortho LC group and among type of teeth in the conventional resin groups . The predominant mode of bracket failure for the unetched Fuji Ortho LC cement was at the enamel-adhesive interface , and for conventional resins , the enamel-adhesive interface and the bracket-adhesive interface . These results suggest that resin-reinforced glass ionomer cement can withst and occlusal and orthodontic forces despite having a bond strength lower than that of conventional resin adhesives OBJECTIVE The purpose of the present study was to analyze the influence of debonding force location in shear bond strength testing of orthodontic brackets in vitro . METHODS Ninety extracted permanent bovine m and ibular incisors were r and omly divided into 3 groups of 30 specimens each . Teeth were bonded with stainless steel orthodontic brackets . Enamel surfaces were etched with 37 % phosphoric acid for 30s and bonded with a composite adhesive .  Debonding force measurements were performed with a universal testing machine . Location of the debonding force was : bracket base ( group A ) , ligature groove ( group B ) , occlusal bracket wings ( group C ) . RESULTS Mean shear bond strength measurements were as follows : 22.70(4.23)MPa ( group A ) , 11.52(2.74)MPa ( group B ) , 9.44(2.96)MPa ( group C ) . Analysis of variance indicated that there were significant differences in shear bond strength . Post-hoc Tukey tests showed that bond strength measurements of group A were significantly different from those of groups B and C. The adhesive remnant index also showed significant differences and ranged from a mean of 1.53 in group A to a mean of 2.10 in group C. SIGNIFICANCE Debonding force location had a significant influence on shear bond strength measurements and bond failure pattern , indicating that this parameter needs to be taken into consideration for inter study comparison of in vitro results Objective : This in vitro study aim ed to compare the microleakage of orthodontic brackets between enamel-adhesive and adhesive-bracket interfaces at the occlusal and gingival margins bonded with different adhesive systems . Material s and Methods : A total of 144 human maxillary premolar teeth extracted for orthodontic reasons was r and omly divided into four groups . Each group was then further divided into three sub-groups . Three total-etching bonding systems ( Transbond XT , Greengloo and Kurasper F ) , three one-step self-etching bonding systems ( Transbond Plus SEP , Bond Force and Clearfil S3 ) , three two-step self-etching bonding systems ( Clearfil SE Bond , Clearfil Protectbond and Clearfil Liner Bond ) , and three self-adhesive resin cements ( Maxcem Elite , Relyx U 100 and Clearfil SA Cement ) were used to bond the brackets to the teeth . After bonding , all teeth were sealed with nail varnish and stained with 0.5 % basic fuchsine for 24 h. All sample s were sectioned and examined under a stereomicroscope to score for microleakage at the adhesive-enamel and adhesive-bracket interfaces from both occlusal and gingival margins . Statistical Analysis Used : Statistical analyses were performed with Kruskal-Wallis and Wilcoxon signed-rank tests . Results : The results indicate no statistically significant differences between the microleakage scores of the adhesives ; microleakage was detected in all groups . Comparison of the average values of the microleakage scores in the enamel-adhesive and adhesive-bracket interfaces indicated statistically significant differences ( P < 0.05 ) . The amount of the microleakage was higher at the enamel-adhesive interface than at the bracket-adhesive interface . Conclusions : All of the brackets exhibited some amount of microleakage . This result means that microleakage does not depend on the type of adhesive used This study evaluated the shear bond strength of stainless steel brackets bonded to enamel with a new fluoride-releasing orthodontic adhesive system . A total of 140 extracted human bicuspids were r and omly divided into four groups . Group I ( Transbond XT ) was a control group in which enamel was etched with phosphoric acid . For the remaining groups , enamel was conditioned with a self-etching primer ( SEP ) : Group II ( Transbond Plus ) , Group III ( BeautyOrtho Bond ) , and Group IV ( BeautyOrtho Bond + Salivatect ) . Stainless steel brackets were bonded to all tooth sample s. After which , the sample s were stored , thermocycled , tested , and statistically analyzed . Besides bond strength evaluation , the adhesive remnant index ( ARI ) was also evaluated . The shear bond strengths of Groups II , III , and IV were significantly lower than Group I , and Group II was significantly greater than that of Group III . Concerning ARI scores , no significant differences were found between the groups . Further , no enamel fracture was observed during shear bond test with the new SEP . In conclusion , when enamel was conditioned with the new SEP , the mean values of shear bond strength yielded were lower than when it was etched with 37 % phosphoric acid . Nonetheless , these mean values were higher than the average suggested by Reynolds as optimum for clinical treatment A clinical trial was carried out to compare the failure rates of a visible light-cured fluoride-releasing material with a chemically cured adhesive .  Fifty patients were used for the trial and 762 brackets were bonded in a split-mouth experimental design . Bracket failures were reported over the full period of orthodontic treatment . Statistical data analysis was carried out by means of chi 2 tests . The results of this study indicate that brackets , bonded with a chemically cured material ( Lee Insta-bond , Lee Pharmaceuticals , EI Monte , Calif. ) , showed significantly fewer failures than brackets bonded with the light-cured material ( Orthon , Orthon Dental Inc. , Victoria , Canada ) . When the site of bond failure was evaluated in an overall manner , there were significantly more lower than upper , and more posterior than anterior bond failures Background The purpose of this in-vitro study was to examine the effect of incorporating different concentrations of Zirconium oxide-Titanium dioxide ( ZrO2-TiO2 ) nanoparticles , which can have antibacterial properties , on the mechanical properties of an orthodontic adhesive . Methods ZrO2-TiO2 ( Zirconium oxide , HWNANO , Hongwu International Group Ltd , China ) -Titanium dioxide , Nanoshell , USA ) nanopowder were incorporated into orthodontic adhesive ( Transbond XT , 3 M Unitek , Monrovia , USA ) with different concentrations ( 0.5 % weight nonofiller and 1 % weight nanofiller ) . The size of nanoparticle was 70–80 nm for ZrO2 and less than 50 nm for TiO2 . For measuring the shear bond strength of the three groups of orthodontic adhesives [ Transbond ( control ) , Transbond mixed with 0.5 % weight ZrO2-TiO2 , and Transbond mixed with 1 % weight ZrO2-TiO2 ] , 30 freshly extracted human first premolars were used and bonded with stainless steel metal brackets ( Dentaurum ® , Discovery ® , Deutschl and ) , using the 3 orthodontic adhesives and 3 M Unitek ; Transbond TM Plus Self-Etching Primer ( 10 sample s in each group ) . The recorded values of compressive strength and tensile strength ( measured separately on 10 sample s of orthodontic adhesives ( add the 3 D size of sample , light cured for 40 s on both sides ) of each orthodontic adhesives ) , as well as the shear bond strength in Mega Pascal unit ( MPa ) were collected and exposed to one-way analysis of variance ( ANOVA ) and Tukey ’s post-hoc tests . Results orthodontic adhesive with 1 % weight ZrO2-TiO2 showed the highest mean compressive ( 73.42 ± 1.55 MPa , p : 0.003 , F : 12.74 ) , tensile strength ( 8.65 ± 0.74 MPa , p : 0.001 , F : 68.20 ) , and shear bond strength ( 20.05 ± 0.2 MPa , p : 0.001 , F : 0.17 ) . Conclusions Adding ZrO2-TiO2 nanoparticle to orthodontic adhesive increased compressive strength , tensile strength , and shear bond strength in vitro , but in vivo studies and r and omized clinical trials are needed to vali date the present findings The objective of this study was to compare 3  orthodontic adhesives  in the areas of shear-peel bond strength , location of adhesive failure , and extent of enamel cracking before bonding and after debonding of orthodontic brackets . The adhesives included a composite resin control ( Transbond XT ; 3M/Unitek , St Paul , Minn ) , a resin-modified glass ionomer cement ( Fuji Ortho LC ; GC America Corp , Alsip , Ill ) , and a polyacid-modified composite resin under dry and saliva-contaminated conditions ( Assure ; Reliance Orthodontic Products Inc , Itasca , Ill ) . Metal brackets were bonded to the buccal surfaces of 160 ( 4 groups of 40 ) human premolars . The bonded teeth were stored in deionized water at 37 degrees C for 30 days and thermocycled for 24 hours before debonding with a Universal Instron ( Instron Corp , Canton , Mass ) testing machine . The extent of cracking in the buccal surfaces was evaluated under 16x magnification before bonding and after debonding . Although the bond strength of the composite resin control ( 20.19 MPa ) was significantly greater ( P < .05 ) than that of the adhesives in the other groups , clinical ly acceptable shear-peel bond strengths were found for all adhesives ( Fuji Ortho LC = 13.57 MPa , Assure-dry = 10.74 MPa , Assure-wet = 10.99 MPa ) . The bond strength for the Assure adhesive was not significantly affected by saliva contamination . The sample of extracted premolars used in this study displayed a greater frequency of buccal surface enamel cracking ( 46.7 % ) than that reported in the literature for in vivo premolars ( 7.8%-10.2 % ) , which was possibly due to the extraction process . The frequency of enamel cracking in a subset of this sample ( n = 34 ) increased from 46.4 % at prebonding to 62.4 % at postdebonding as a result of the forces of debonding The purpose of this study was to determine the effect of changing the crosshead speed of the testing machine on the shear bond strength of orthodontic brackets to enamel while st and ardizing all the other variables . Forty freshly extracted human molars were bonded using the Transbond XT adhesive system ( 3 M Unitek , Monrovia , Calif ) . The teeth were r and omly divided into two groups . In group I , the shear bond strength was measured at a crosshead speed of 5.0 mm/min , and in group II the shear bond strength was measured at a crosshead speed of 0.5 mm/ min . Within half an hour from the initial bonding of each tooth , an occlusogingival load was applied to the bracket , producing a shear force at the bracket-tooth interface . This was accomplished by using the flattened end of a steel rod attached to the crosshead of a Universal Test Machine ( Zwick GmbH & Co , Ulm , Germany ) . The t-test results ( t = 2.71 ) indicated that there was a significant difference ( P = .014 ) in the shear bond strengths between the group tested at a crosshead speed of 5.0 mm/min and the group tested at a crosshead speed of 0.5 mm/min . The mean shear bond strengths for the two groups were 7.0 + /- 4.6 MPa and 12.2 + /- 4.0 MPa , respectively . These findings indicated that it is important to identify the parameters included in shear bond testing in order to enable meaningful comparisons of the performance of different material The objectives of this study were ( 1 ) to compare the in vivo survival rates of orthodontic brackets bonded with a resin-modified glass ionomer adhesive ( Fuji Ortho LC ; GC America , Alsip , Ill ) after conditioning with 10 % polyacrylic acid and a conventional resin adhesive ( Light Bond ; Reliance Orthodontic Products , Itasca , Ill ) bonded with 37 % phosphoric acid , ( 2 ) to compare the in vitro bond shear/peel bond strength between the 2 adhesives , ( 3 ) to determine the mode of bracket failure in the in vivo and in vitro tests according to the adhesive remnant index ( ARI ) , and ( 4 ) to compare the changes in surface morphology of enamel surface after etching or conditioning with 10 % polyacrylic acid , with scanning electron microscopy . In the in vitro study , 50 extracted premolars were r and omly divided into 4 groups : brackets bonded with Fuji Ortho LC or Light Bond adhesive that were debonded after either 30 minutes or 24 hours . Bond strengths were determined with a testing machine at a crosshead speed of 1 mm/min . Data were analyzed with analysis of variance and a paired Student t test . The in vivo study consisted of 398 teeth that were r and omly bonded with Fuji Ortho LC or Light Bond adhesive in 22 subjects with the split-mouth technique . Bracket survival rates and distribution were followed for 1.3 years . Data were analyzed with Kaplan-Meier product-limit estimates of survivorship function . The in vitro study results showed significant differences ( P < .05 ) among the adhesives and the debond times . Light Bond had significantly greater bond strengths than Fuji Ortho LC at 24 hours ( 18.46 + /- 2.95 MPa vs 9.56 + /- 1.85 MPa ) and 30 minutes ( 16.19 + /- 2.04 MPa vs 6.93 + /- 1.93 MPa ) . Mean ARI scores showed that Fuji Ortho LC had significantly greater incidences of enamel/adhesive failure than Light Bond adhesive ( 4.9 vs 4.1 ) . For the in vivo study , no significant differences in failure rate , sex , or location in dental arch or ARI ratings were found between the 2 adhesives . These results suggest that , compared with conventional resin , brackets bonded with resin-modified glass ionomer adhesive had significantly less shear bond strength in vitro . However , similar survival rates of the 2 material s studied after 1.3 years indicate that resin-reinforced glass ionomers can provide adequate bond strengths clinical ly . The weaker chemical bonding between the adhesive and the enamel might make it easier for clinicians to clean up adhesives on the enamel surface after debonding The aim of this in vitro study was to evaluate the bond strength of a self-etching adhesive system to dentine irrigated with sodium hypochlorite ( NaOCl ) , chlorhexidine solution ( CX ) and ethylene diamine tetra acetic acid ( EDTA ) by microtensile testing . Sixty human third molars were sectioned 3 mm below the occlusal level and then r and omly divided into six groups : G1(control ) , without irrigant solution ; G2 , 1 % NaOCl ; G3 , 1 % NaOCl followed by the application of 17 % EDTA ; G4 , 2 % CX ; G5 , 2 % CX followed by the application of 17 % EDTA and G6 , 17 % EDTA . The specimens received the self-etching adhesive system were restored with composite resin , then sectioned and trimmed to obtain four hourglass-shaped slabs from each tooth . The specimens were su bmi tted to the microtensile test in a Universal Testing Machine at a crosshead speed of 0.5 mm min(-1 ) until fracture . The results were su bmi tted to statistical analysis by anova /Newman-Keuls . The means and st and ard deviations ( MPa ) were : G1 , 26.88 ( ±3.81 ) ; G2 , 19.08 ( ±3.89 ) ; G3 , 18.16 ( ±2.21 ) ; G4 , 18.14 ( ±4.32 ) ; G5 , 34.30 ( ±3.32 ) ; G6 , 13.61 ( ±1.21 ) . It was concluded that the application of 2 % CX followed by the application of 17 % EDTA result ed in increasing the bond strength of the self-etching adhesive system to dentine , when compared with the results obtained for the other tested groups Objective To compare bond failure rates between direct and indirect techniques for bonding orthodontic brackets . Design A two-centre single blinded prospect i ve r and omized controlled clinical trial . Material s and methods This study was undertaken at the Birmingham Dental Hospital and Good Hope Hospital , Sutton Coldfield . Thirty-three subjects meeting the inclusion criteria were selected from orthodontic waiting lists and assigned to either of two study groups according to a split-mouth study design . The number and site of bracket failures between tooth types was recorded over 1 year . Statistical analysis was carried out using chi-square tests . Results Brackets were lost from 14 of the 553 teeth bonded , giving an overall bond failure rate of 2.5 % . There were no significant differences in bond failures between direct and indirect bonding or in the tooth types of the failures . Conclusions There was no significant difference in the bond failure rates between direct and indirect bonding Background The purpose of this clinical longitudinal study was to investigate the effectiveness of indirect bonding technique evaluating the number of bond failures which occurred during treatment . Methods Fifty-two patients were selected and divided into two groups : group A ( 33 patients ) bonded with the direct technique and group B ( 19 patients ) bonded with the indirect technique . The number and date of bracket failure were recorded for over 15 months . Moreover , also the effect of crowding level on bracket failures was calculated . Statistical analysis was performed by means of t-test , Kaplan-Meier survival estimates and chi-squared test . Results No statistically significant differences were found in the total bond failure rate between direct and indirect techniques , also when comparing the upper and lower arches . The only significant difference was found comparing the posterior segment of the lower arches , in which a higher percentage of detachments were recorded in group B , bonded with the indirect technique . Moreover , no significant differences between direct and indirect bonding were found when evaluating crowding level . Conclusions Orthodontic practitioners can safely use the indirect bonding technique , even in patients with severe crowding , because it does not influence the adhesive quality and the bracket survival rate
The review reached no real conclusion apart from the lack of efforts to clinical ly evaluate the bonding efficiency of a wide range of orthodontic bracket-adhesive systems in terms of debonding force compared to laboratory-based in vitro and ex vivo studies
The aim of this study was to systematic ally review the available studies measuring the bond strength of  orthodontic bracket-adhesive system  under different experimental conditions in vivo .