Media playback is unsupported on your device Media caption The BBC's Khaled Ezzelarab: "The president seems to have lost control over the security forces" 
 
 Anti-government protesters in Egypt have stormed the national headquarters of President Mohammed Morsi's Muslim Brotherhood in the capital, Cairo. 
 
 People ransacked the building in the Moqattam area and set parts on fire. 
 
 Officials say eight people have been killed in clashes outside since Sunday, while eight others have died elsewhere. 
 
 Meanwhile, four ministers are reported to have resigned, a day after millions took to the streets across the country to demand the president leave power. 
 
 The al-Watan website said the ministers of tourism, environment, communication and legal affairs had acted "in solidarity with the people's demand to overthrow the regime". 
 
 On Monday afternoon, Egyptian state television reported the armed forces would issue a statement on the situation later in the day, but did not provide further details. 
 
 Earlier, the opposition movement behind the protests, Tamarod (Revolt), gave Mr Morsi until Tuesday afternoon to step down and call fresh presidential elections, or else face a campaign of civil disobedience. 
 
 Analysis All sides in Egypt were surprised by the huge scale of the demonstrations against the president. The opposition is a broad and informal coalition, which ranges from supporters of the old Mubarak regime to people who risked their lives to topple it. Their challenge is to find a way to sustain the momentum of Sunday's protests. President Morsi's spokesman has called for dialogue. For that to work, the president would have to offer major concessions, perhaps on a rewritten constitution. He showed no signs of conciliation during a major political speech last week, instead appealing to his Muslim Brotherhood base. As for the demonstrators, they have called for his resignation and early elections. Political chaos looks likely to continue. 
 
 Protesters across Egypt accuse the president of failing to tackle economic and security problems since being elected a year ago. His supporters insist he needs more time. 
 
 'Dangerous' 
 
 The crowds seen in Cairo's Tahrir Square on Sunday were the biggest since the 2011 revolution that toppled Hosni Mubarak. 
 
 Protests and sporadic outbreaks of violence were reported nationwide. 
 
 The health ministry said at least 16 people had been killed and 781 injured since Sunday. 
 
 Three people died in the central province of Assiut, and another four in Alexandria, Fayoum, Beni Suef and Kafr al-Sheikh. Another protester suffocated to death at a protest outside the Ittihadiya presidential palace in Cairo. 
 
 Eight people were killed in clashes around the Muslim Brotherhood's headquarters in Moqattam, the ministry added. 
 
 Overnight, protesters threw petrol bombs and rocks at armed guards inside the six-storey building, who retaliated by firing at them. 
 
 On Monday morning, the protesters stormed the headquarters and began throwing objects out of broken windows. One protester was seen removing parts of the signage, while another waved an Egyptian flag from a window. Later, people began walking out carrying office equipment. 
 
 Image caption Protesters ransacked the Cairo headquarters of President Mohammed Morsi's Muslim Brotherhood group early on Monday. Image caption Earlier, the Tamarod protest group gave Mr Morsi a day to leave step down, a year after he took office. Image caption The crowd in Tahrir Square on Sunday was the biggest since the revolution in 2011. Hundreds returned to the square on Monday. Image caption Many protesters spent the night on the streets of Cairo, including outside the Ittihadiya presidential palace. Image caption Protesters across Egypt have accused the president of failing to tackle economic and security problems. previous slide next slide 
 
 "This is a historic moment. The Brotherhood ruined the country, so stealing from them is justified," one man, named Mohammed, told the AFP news agency. 
 
 Many protesters accuse the president of putting the Brotherhood's interests ahead of the country's as a whole. 
 
 Brotherhood spokesman Gehad El-Haddad criticised the security forces for failing to protect the building and warned that the movement was considering action to defend itself. 
 
 "It's very dangerous for one entity in society to take up violence as a means of change because it may entice others to do so," he told the Reuters news agency. 
 
 Mr Haddad noted that self-defence committees had been set up during the 2011 uprising, and said the Brotherhood's Guidance Bureau would make an announcement later on Monday. 
 
 "The people will not sit silent," he added. 
 
 'Constitutional legitimacy' 
 
 Some protesters had spent the night camped out in Tahrir Square and also in front of the Ittihadiya presidential palace to the north-east. They vowed to stay there until the president stepped down. 
 
 One man heading to the palace was confident it would not take long. 
 
 Tamarod (Revolt) The Tamarod movement says more than 22 million people have signed a petition complaining that: Security has not been restored since the 2011 revolution that toppled Hosni Mubarak 
 
 The poor "have no place" in society 
 
 The government has had to "beg" the International Monetary Fund (IMF) for a $4.8bn loan to help shore up the public finances 
 
 There has been "no justice" for people killed by security forces during the uprising and at anti-government protests since then 
 
 "No dignity is left" for Egyptians or their country 
 
 The economy has "collapsed", with growth poor and inflation high 
 
 Egypt is "following in the footsteps" of the US Egypt deeply polarised as Morsi marks first year 
 
 "Mubarak took only 18 days although he had behind him the security, intelligence and a large sector of Egyptians," Amr Tawfeeq told the Associated Press. 
 
 Earlier, Tamarod issued a statement saying the protesters would give Mr Morsi until 17:00 (15:00 GMT) on Tuesday to leave power and allow state institutions to prepare for early presidential elections. 
 
 Otherwise, people would begin a campaign of "complete civil disobedience", the group warned. 
 
 It urged "state institutions including the army, the police and the judiciary, to clearly side with the popular will as represented by the crowds". 
 
 The group also rejected offers of dialogue from the president. 
 
 "There is no way to accept any half measures," it said. "There is no alternative other than the peaceful end of power of the Muslim Brotherhood and its representative, Mohammed Morsi." 
 
 On Saturday, Tamarod said it had collected more than 22 million signatures - more than a quarter of Egypt's population - in support. 
 
 But Mr Morsi was defiant in an interview published on Sunday, rejecting the opposition calls for early presidential elections. 
 
 "If we changed someone in office who [was elected] according to constitutional legitimacy - well, there will be people opposing the new president too, and a week or a month later they will ask him to step down," he told the Guardian newspaper. 
 
 "There is no room for any talk against this constitutional legitimacy. There can be demonstrations and people expressing their opinions. But what's critical in all this is the adoption and application of the constitution." ||||| Media playback is unsupported on your device Media caption The BBC's Aleem Maqbool in Tahrir Square says the size of the protest has been wholly unexpected 
 
 Huge protests across Egypt calling for the resignation of President Mohammed Morsi have taken place through the night, with some outbreaks of violence. 
 
 In the capital, Cairo, tens of thousands of people massed in Tahrir Square and outside the presidential palace in the biggest demonstration there since the 2011 revolution. 
 
 At least one person was killed in clashes at Cairo's headquarters of Mr Morsi's Muslim Brotherhood movement. 
 
 Four others died in clashes elsewhere. 
 
 Millions of protesters across the country accuse the country's first Islamist president of failing to tackle economic and security problems since taking power a year ago. 
 
 The most striking aspect of the protests in Alexandria is the variety of people here - veiled and non-veiled Mahmoud Abu Bakr, Alexandria Angry mood in provincial Egypt 
 
 The demonstration was largely peaceful, but some protesters later threw stones and petrol bombs at the Cairo headquarters of the Muslim Brotherhood. 
 
 At least one person was killed when shooting broke out near the political office, activists and a hospital official said. 
 
 Meanwhile, thousands of Mr Morsi supporters staged a rally in the Cairo suburb of Nasr City. 
 
 A presidential spokesman later urged the protesters to respect the democratic process, referring to Mr Morsi's victory in last year's elections which were widely seen as free and fair. 
 
 Analysis Many of those on the streets feel betrayed by a president who they say has been uninterested in uniting Egyptians despite once promising to be inclusive. They feel that he has instead governed purely in the interests of his own party. For his part, the president insists he has invited opposition groups to enter into dialogue but that they have not co-operated. His supporters say that whatever the considerable problems Egypt is facing, Mohammed Morsi must see out his full term in office for the sake of stability. Some pro-Morsi demonstrators have decided to stage their own sit-ins, and there are fears of clashes between opposing groups. The coming hours, and the way the situation is handled by the authorities, are likely to give us clear indications about whether or not Egypt's president can survive in office as he insists he will. 
 
 One clear achievement of President Morsi's opponents has been to get so many people out on to the streets, BBC's Middle East editor Jeremy Bowen reports from Cairo. 
 
 The last time such numbers were seen on the square was during the revolution in 2011 which saw the removal of President Hosni Mubarak from power. 
 
 The question they face now is how to fashion a political strategy that can rival the organisation of the Muslim Brotherhood, he says. 
 
 Another big question, he adds, is what the army will do. The defence minister has warned that the military may intervene if Egypt becomes ungovernable. 
 
 Society split 
 
 On Sunday, one man was killed and at least 24 injured in Beni Suef, 115km (71 miles) south of Cairo, security sources said. 
 
 According to a report on the Ahram news website, Morsi supporters attacked an opposition rally and unidentified gunmen opened fire. The report could not be confirmed independently. 
 
 Image copyright AFP Image caption A huge crowd of protesters stretched along an avenue near the presidential palace in Cairo on Sunday evening Image copyright Reuters Image caption Tahrir Square, focus of the uprising which ousted Hosni Mubarak, teemed with protesters Image copyright AP Image caption A protester in Cairo held a crossed-out photo of President Morsi framed with a tyre Image copyright AP Image caption In one picture police officers are seen in the middle of opposition supporters in Cairo Image copyright Reuters Image caption A big rally against Mr Morsi took place in Alexandria too Image copyright Reuters Image caption Alexandria was the scene of bloody fighting earlier this week previous slide next slide 
 
 In the southern city of Assiut, three people died and several were injured when shots were fired at protesters, reportedly by attackers on a motorcycle. 
 
 According to the health ministry, 253 people were injured across the country during Sunday's protests. 
 
 Mohammed Morsi's first year Image copyright AP June 2012 - Narrowly wins presidential election. Orders parliament to meet in defiance of a military decree dissolving it 
 
 Narrowly wins presidential election. Orders parliament to meet in defiance of a military decree dissolving it July 2012 - Submits to a Supreme Court ruling that the parliamentary elections were invalid 
 
 Submits to a Supreme Court ruling that the parliamentary elections were invalid August 2012 - Dismisses Defence Minister Hussein Tantawi and Chief of Staff Sami Annan, and strips military of say in legislation and drafting the new constitution 
 
 Dismisses Defence Minister Hussein Tantawi and Chief of Staff Sami Annan, and strips military of say in legislation and drafting the new constitution November 2012 - Rescinds a decree stripping the judiciary of the right to challenge his decisions, after popular protests 
 
 - Rescinds a decree stripping the judiciary of the right to challenge his decisions, after popular protests December 2012 - Public vote approves draft constitution boosting the role of Islam and restricting freedom of speech and assembly 
 
 Public vote approves draft constitution boosting the role of Islam and restricting freedom of speech and assembly March 2013 - Court halts his plans to bring parliamentary elections forward to April, citing failure to refer the electoral law to the Constitutional Court 
 
 Court halts his plans to bring parliamentary elections forward to April, citing failure to refer the electoral law to the Constitutional Court June 2013 - Puts Islamists in charge of 13 of Egypt's 27 governorships - controversially he appoints a member of the former armed group Gamaa Islamiya to be governor of Luxor Polarisation marks Morsi's first year Egyptian views of Morsi one year on Families torn by political divide 
 
 In Cairo, unidentified persons attacked the Muslim Brotherhood headquarters, which had been fortified with sandbags earlier. Staff inside said they had not broken in, Reuters news agency reports. 
 
 Demonstrations were also held in Alexandria, Port Said, Suez and other cities. 
 
 Presidential spokesman Ihab Fahmi called on all Egyptians to "unite and listen to the sound of wisdom". 
 
 "Political diversity necessitates on all parties to abide by the democratic process," he said. 
 
 And he reiterated that President Morsi was open to a "real and serious national dialogue". 
 
 As darkness fell, the opposition National Salvation Front (NSF) released what it called "Revolution Statement 1", calling on protesters across Egypt to "maintain their peaceful [rallies] in all the squares and streets and villages and hamlets of the country... until the last of this dictatorial regime falls". 
 
 The NSF is among liberal and secular opposition groups which have endorsed a petition organised by the grassroots movement Tamarod (Rebellion), which calls for a snap election. Opposition activists say more than 22 million people have signed it. 
 
 There was also some evidence of anti-American and anti-Israeli feeling among the protesters, with one flag portraying President Morsi inside a Star of David. 
 
 The BBC's Aleem Maqbool in Cairo says many ordinary Egyptians - angered by Mr Morsi's political and economic policies - have been taking part in the rally in Tahrir Square. 
 
 At one point, army helicopters flew over Tahrir Square and dropped Egyptian flags, to cheers from the anti-Morsi crowd, he says. 
 
 Mr Morsi, who hails from the Muslim Brotherhood, became president on 30 June 2012. 
 
 His first year as president has been marred by constant political unrest and a sinking economy. ||||| Media playback is unsupported on your device Media caption Egyptian state television is saying the unrest is "terrorism" 
 
 The head of Egypt's armed forces has said that his message to the supporters of ousted President Mohammed Morsi is that "there is room for everyone". 
 
 Gen Abdul Fattah al-Sisi urged them to help "rebuild the democratic path" and "integrate in the political process". 
 
 But he also warned the military would not be silent in the face of violence. 
 
 Later, at least 36 detained members of the Muslim Brotherhood were killed when they tried to escape during their transfer to a prison outside Cairo. 
 
 Initially, the interior ministry said they died in an exchange of fire after some of them took a military officer hostage and the convoy of prison vehicles, transporting a total of 612 detainees to Abu Zaabal prison in Qalyubia province, was attacked by unidentified gunmen. 
 
 But later the ministry said the prisoners died from the effects of inhaling tear gas, which was fired when the escaping detainees took a police officer hostage. He was freed, but was badly injured, it added. 
 
 A legal source told the Reuters news agency that the Brotherhood members had suffocated in the back of a crammed police van. 
 
 The interior ministry separately said so-called "people's committees", which have been set up by residents of some areas to provide security, would be banned because some had been used for vigilante activities. 
 
 Crisis timeline 3 Jul: President Mohammed Morsi deposed by military after mass protests 
 
 President Mohammed Morsi deposed by military after mass protests 4 Jul: Pro-Morsi protesters gather at the Rabaa al-Adawiya (above) and Nahda sites in Cairo 
 
 Pro-Morsi protesters gather at the Rabaa al-Adawiya (above) and Nahda sites in Cairo 27 Jul: More than 70 people killed in clashes with security forces at Rabaa al-Adawiya 
 
 More than 70 people killed in clashes with security forces at Rabaa al-Adawiya 14 Aug: Security forces break up both camps, leaving at least 638 people dead 
 
 Security forces break up both camps, leaving at least 638 people dead 16 Aug: Muslim Brotherhood holds "day of anger" protest in Ramses Square, Cairo. Clashes leave at least 173 dead 
 
 Muslim Brotherhood holds "day of anger" protest in Ramses Square, Cairo. Clashes leave at least 173 dead 17 Aug: Siege at al-Fath mosque in Cairo; 79 killed in political violence nationwide 
 
 Siege at al-Fath mosque in Cairo; 79 killed in political violence nationwide 18 Aug: 36 detained Brotherhood members are killed while attempting to escape prison vehicles Timeline: Pro-Morsi protests Who is who in Muslim Brotherhood In pictures: Cairo mosque siege 
 
 Meanwhile, Mena reported that 79 people were killed and 549 wounded in violence across the country on Saturday. 
 
 That raised the nationwide death toll since Wednesday, when security forces forcibly cleared two pro-Morsi protest camps in Cairo, to more than 830, including 70 police and soldiers. 
 
 'Torching the nation' 
 
 Gen Sisi deposed Mr Morsi on 3 July, saying the military could not ignore the millions of people who had been demanding the resignation of Egypt's first democratically elected president. 
 
 Before security forces launched the operation to disperse the Cairo sit-ins, the armed forces chief asked millions of people to take to the streets to give him a "mandate" to fight "violence and terrorism", an apparent reference to the Muslim Brotherhood, the Islamist movement to which Mr Morsi belongs. 
 
 In a speech to army and police officers on Sunday, Gen Sisi warned that the military would not allow further violence after the latest unrest. 
 
 "We will not stand by silently watching the destruction of the country and the people or the torching the nation and terrorising the citizens," he quoted as saying on the military's Facebook page. 
 
 But the general also appeared to strike a conciliatory tone towards his opponents, urging them to join in the political process. 
 
 "There is room for everyone in Egypt, and we are cautious about every drop of Egyptian blood." 
 
 The Brotherhood has called for daily demonstrations since security forces cleared its protest camps in Cairo on Wednesday and declared a state of emergency. 
 
 More than 600 people were killed during the operations, including dozens of security forces personnel, and at least another 173 died on Friday during a "day of rage" called by the Brotherhood . 
 
 Brotherhood members detained 
 
 Also on Sunday, the interim government met to discuss the unrest. 
 
 Afterwards, Information Minister Dorreya Sharaf al-Din said the cabinet wished to express its regret the loss of life, but would continue to confront "terrorism" firmly. 
 
 Media playback is unsupported on your device Media caption Bethany Bell asks Cairo residents for their views on the political conflict engulfing Egypt 
 
 She added that the cabinet would name several streets and squares after soldiers killed in the recent unrest, and review the legal status of al-Jazeera TV, which she accused of threatening security and stability. 
 
 The cabinet is also believed to have discussed Prime Minister Hazem Beblawi's proposal for the legal dissolution of the Brotherhood. 
 
 The 85-year-old Islamist movement was banned by Egypt's military rulers in 1954, but registered itself as a non-governmental organisation in March in response to a court case bought by opponents who contested its legal status. 
 
 The Brotherhood also has a legally registered political wing, the Freedom and Justice Party, which was set up in June 2011 as a "non-theocratic" group after the uprising that forced President Hosni Mubarak from power. 
 
 At a news conference on Sunday, the interim Foreign Minister, Nabil Fahmy, showed video clips apparently showing armed protesters firing on security forces in Cairo. He said the government was faced with an attempt to "shake the foundation of the state". 
 
 More than 1,000 Brotherhood members have been detained in raids since Wednesday, with officials saying bombs, weapons and ammunition have been seized. Some 300 were held in several cities on Sunday, including Cairo, Alexandria, Assiut and Suez, security sources said. 
 
 EU concerns 
 
 Earlier, the European Union said it would be reviewing its relationship with Egypt's interim authorities at an emergency meeting next week. 
 
 Image caption Footage from Ismailiya shows a Morsi supporter confronting tanks on Friday. The unverified video shows the man then being shot and falling 
 
 The presidents of the European Commission and European Council said in a joint statement calls for democracy and fundamental rights "cannot be disregarded, much less washed away in blood". 
 
 It added that the violence and killings "cannot be justified nor condoned". 
 
 The EU has pledged several billion dollars in loans and grants to Egypt. 
 
 Mr Fahmy sought to pre-empt any attempt by the West to compel the interim authorities to back down by announcing that he would be reviewing all foreign assistance. 
 
 "I want to determine what is useful and what is not and what aid is being used to pressure Egypt and whether this aid has good intentions and credibility. We will proceed based on our findings," he told reporters. 
 
 Correction 19 August 2013: An earlier version of this story which said Muslim Brotherhood members and their supporters had attacked churches, police stations and the homes and businesses of Christians should have attributed this as a claim made by the authorities.
– Officials say three anti-government protesters have been killed in the southern Egyptian city of Assiut, after suspected Islamists riding a motorbike fired on protesters outside a local government building. One was killed and seven injured, prompting protesters to march on the local office of the Muslim Brotherhood's Freedom and Justice party, where at least two more were shot by gunmen inside the building, the AP reports. Another protester was killed outside Freedom and Justice party headquarters in Beni Suef. The country is gripped with anti-government protests today, with hundreds of thousands massing in Cairo's Tahrir Square and other cities around the country to call for the removal of President Mohamed Morsi, the AP reports. "Today is the Brotherhood's last day in power," says one protestor at Tahrir. "I came here today because Morsi did not accomplish any of the [2011] revolution's goals ... the needs of the poor were not met." But Morsi, who has three years left in office, remains defiant in the face of growing opposition and calls for an early election. "If we changed someone in office who [was elected] according to constitutional legitimacy—well, there will be people opposing the new president too, and a week or a month later they will ask him to step down," he told the Guardian.