MIRANSHAH, Pakistan (Reuters) - A U.S. drone strike on suspected Islamist militants in northwest Pakistan killed 10 people on Thursday, Pakistani intelligence officials said, an attack likely to raise tensions in a standoff with Washington over NATO supply routes to Afghanistan. 
 
 The pilotless drone aircraft attacked a compound in a village in North Waziristan, a day after a similar attack killed four suspected militants in the same region. 
 
 "The drone fired two missiles at the compound. We believe it was being used by militants," one of the Pakistani officials said. 
 
 The United States has been urging Pakistan to mount an offensive in North Waziristan to pursue members of the Haqqani militant network, one of Washington's most feared foes in neighboring Afghanistan. 
 
 That looks more unlikely than ever, as a result of a crisis in relations between Washington and Islamabad over a range of issues. 
 
 The United States has been pushing Pakistan to re-open supply routes to NATO forces in Afghanistan in difficult talks that show no signs of a breakthrough any time soon. 
 
 Pakistan closed the routes, which are seen as vital to the planned withdrawal of most foreign troops from Afghanistan before the end of 2014, in protest against last November's killing of 24 Pakistani soldiers in a NATO air attack along the Afghan border. 
 
 U.S. frustrations with Pakistan deepened on Wednesday after Pakistani authorities sentenced a doctor accused of helping the CIA find Osama bin Laden to 33 years in jail on charges of treason. 
 
 Attacks by unmanned drone aircraft, which U.S. officials say are highly effective against militants, fuel anti-American sentiment in Pakistan because they are seen as violations of sovereignty that inflict civilian casualties. 
 
 After a review of ties with the United States following the killing of the 24 Pakistani soldiers, Pakistan's parliament demanded an end to drone strikes. 
 
 Pakistan has spelt out in no uncertain terms that the drone attacks inside its territory must stop, but Washington is not listening, Foreign Minister Hina Rabbani Khar told Reuters in an interview in April. 
 
 Analysts say the CIA could not kill high-value al Qaeda or Taliban militants without cooperation from Pakistani authorities, unless intelligence from informants on the ground used in drone strikes has improved dramatically. 
 
 (Additional reporting by Jibran Ahmad in PESHAWAR; Writing by Michael Georgy; Editing by Daniel Magnowski) ||||| Deputy Pakistani Taliban leader Wali-ur-Rehman (C) is flanked by militants as he speaks to a group of reporters in Shawal town, which lies between North and South Waziristan region in the northwest bordering Afghanistan, in this July 28, 2011 file photo. 
 
 PESHAWAR, Pakistan A U.S. drone strike killed the number two of the Pakistani Taliban in the North Waziristan region on Wednesday, three security officials said, in what would be a major blow in the fight against militancy. 
 
 The drone strike killed seven people, Pakistani security officials said, including Taliban deputy commander Wali-ur-Rehman, in the first such attack since a May 11 general election in which the use of the unmanned aircraft was a major issue. 
 
 Wali-ur-Rehman had been poised to succeed Hakimullah Mehsud as leader of the Pakistani Taliban, a senior army official based in the South Waziristan region, had said in December. 
 
 "This is a huge blow to militants and a win in the fight against insurgents," one security official told Reuters, declining further comment. 
 
 The Pakistani Taliban are a separate entity allied to the Afghan Taliban. Known as the Tehreek-e-Taliban Pakistan (TTP), they have launched devastating attacks against the Pakistani military and civilians. 
 
 Pakistani Taliban spokesman Ihsanullah Ihsan told Reuters the group did not have "confirmed reports" that Wali-ur-Rehman had been killed. He declined further comment. 
 
 Drone casualties are difficult to verify. Foreign journalists must have permission from the military to visit the Pashtun tribal areas along the Afghan border. 
 
 Taliban fighters also often seal off the sites of drone strikes immediately so Pakistani journalists cannot see the victims. 
 
 "That the Taliban are remaining silent and neither denying or confirming the news is itself peculiar," said Saleem Safi, a Pakistani expert on the Taliban. "But if this news is true, then the Pakistan army has the U.S. to thank." 
 
 The security officials and Pashtun tribesmen in the northwestern region said the drone fired two missiles that struck a mud-built house at Chashma village, 3 km (2 miles) east of Miranshah, the region's administrative town. 
 
 They said seven people were killed and four wounded. 
 
 FOREIGN MINISTRY DENOUNCES DRONES 
 
 "Tribesmen started rescue work an hour after the attack and recovered seven bodies," said resident Bashir Dawar. "The bodies were badly damaged and beyond recognition." 
 
 The Pakistan government had yet to confirm Wali-ur-Rehman's death. 
 
 A U.S. drone killed Pakistani Taliban commander Baitullah Mehsud in 2009. There had been several reports that his successor, Hakimullah Mehsud, was killed the same way but they turned out to be untrue. 
 
 But the Foreign Ministry again denounced drones in general on Wednesday. 
 
 "The government has consistently maintained that the drone strikes are counter-productive, entail loss of innocent civilian lives, have human rights and humanitarian implications and violate the principles of national sovereignty, territorial integrity and international law," it said. 
 
 U.S. President Barack Obama recently indicated he was scaling back the drone strike program, winning cautious approval from Pakistan, a key ally in the U.S. fight on militancy. 
 
 North Waziristan is on the Afghan border and has long been a stronghold of militants including Afghan Taliban and their al Qaeda and Pakistani Taliban allies. 
 
 Prime Minister-elect Nawaz Sharif said this month that drone strikes were a "challenge" to Pakistan's sovereignty. 
 
 "We will sit with our American friends and talk to them about this issue," he said. 
 
 Obama's announcement of scaling back drone strikes was widely welcomed by the people of North Waziristan, where drones armed with missiles have carried out the most strikes against militants over the past seven years, sometimes with heavy civilian casualties. 
 
 The strike also coincided with the first session of the newly elected provincial assembly of Khyber Pakhtunkhwa, the former Northwest Frontier Province. 
 
 Former cricketer Imran Khan's Pakistan Tehrik-e-Insaf party won most seats in the assembly and denounced the strike, saying Obama had gone back on his word. 
 
 (Additional reporting by Mehreen Zahra-Malik and Syed Raza Hassan in Islamabad, Saud Mehsud in Dera Ismail Khan; Writing by Nick Macfie; Editing by Robert Birsel)
– The Taliban is being controlled by Pakistan and Islamabad could bring fighting in Afghanistan to a halt "in weeks" if it gave the order, the chief of the Afghan National Army tells the BBC. The Taliban's "leadership is in Pakistan," Sher Mohammad Karimi says, accusing Afghanistan's neighbor of "unleashing" the militants on the country. A NATO report earlier this year found that Pakistan was well aware that Taliban leaders had found refuge within its borders. Despite its public denunciations of drone strikes, Pakistan is complicit in the program and gives the US military lists of targets, Karimi claims. "The drones are used against those Taliban who are Pakistani Taliban," he says. "The drones are never used against Haqqani or Afghan Taliban." Pakistan says at least 17 people were killed in a US drone strike in the North Waziristan region today, the biggest such strike this year, Reuters reports.