In current clinical practices, electroencephalograms (EEG) are reviewed and analyzed by trained neurologists to provide supports for therapeutic decisions. Manual reviews can be laborious and error prone. Automatic and accurate seizure non-seizure classification methods are desirable. A critical challenge is that seizure morphologies exhibit considerable variabilities. In order to capture essential seizure features, this paper leverages an emerging deep learning model, the independently recurrent neural network (IndRNN), to construct a new approach for the seizure non-seizure classification. This new approach gradually expands the time scales, thereby extracting temporal and spatial features from the local time duration to the entire record. Evaluations are conducted with cross-validation experiments across subjects over the noisy data of CHB-MIT. Experimental results demonstrate that the proposed approach outperforms the current state-of-the-art methods. In addition, we explore how the segment length affects the classification performance. Thirteen different segment lengths are assessed, showing that the classification performance varies over the segment lengths, and the maximal fluctuating margin is more than 4 . Thus, the segment length is an important factor influencing the classification performance.
explore two kinds of neural networks over TUH EEG Corpus @cite_21 . Their experiment results show that convolutional LSTM network outperforms convolutional GRU network. Different initialization and regularization methods are considered. LSTM and GRU are limited when using multiple layers.
@cite_21
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Recurrent Neural Networks (RNNs) with sophisticated units that implement a gating mechanism have emerged as powerful technique for modeling sequential signals such as speech or electroencephalography (EEG). The latter is the focus on this paper. A significant big data resource, known as the TUH EEG Corpus (TUEEG), has recently become available for EEG research, creating a unique opportunity to evaluate these recurrent units on the task of seizure detection. In this study, we compare two types of recurrent units: long short-term memory units (LSTM) and gated recurrent units (GRU). These are evaluated using a state of the art hybrid architecture that integrates Convolutional Neural Networks (CNNs) with RNNs. We also investigate a variety of initialization methods and show that initialization is crucial since poorly initialized networks cannot be trained. Furthermore, we explore regularization of these convolutional gated recurrent networks to address the problem of overfitting. Our experiments revealed that convolutional LSTM networks can achieve significantly better performance than convolutional GRU networks. The convolutional LSTM architecture with proper initialization and regularization delivers 30 sensitivity at 6 false alarms per 24 hours. In this work, we investigate the use of sparsity-inducing regularizers during training of Convolution Neural Networks (CNNs). These regularizers encourage that fewer connections in the convolution and fully connected layers take non-zero values and in effect result in sparse connectivity between hidden units in the deep network. This in turn reduces the memory and runtime cost involved in deploying the learned CNNs. We show that training with such regularization can still be performed using stochastic gradient descent implying that it can be used easily in existing codebases. Experimental evaluation of our approach on MNIST, CIFAR, and ImageNet datasets shows that our regularizers can result in dramatic reductions in memory requirements. For instance, when applied on AlexNet, our method can reduce the memory consumption by a factor of four with minimal loss in accuracy. We trained a large, deep convolutional neural network to classify the 1.2 million high-resolution images in the ImageNet LSVRC-2010 contest into the 1000 different classes. On the test data, we achieved top-1 and top-5 error rates of 37.5 and 17.0 which is considerably better than the previous state-of-the-art. The neural network, which has 60 million parameters and 650,000 neurons, consists of five convolutional layers, some of which are followed by max-pooling layers, and three fully-connected layers with a final 1000-way softmax. To make training faster, we used non-saturating neurons and a very efficient GPU implementation of the convolution operation. To reduce overriding in the fully-connected layers we employed a recently-developed regularization method called "dropout" that proved to be very effective. We also entered a variant of this model in the ILSVRC-2012 competition and achieved a winning top-5 test error rate of 15.3 , compared to 26.2 achieved by the second-best entry. Abstract Long-short term memory networks (LSTMs), which have recently emerged in sequential data analysis, are the most widely used type of recurrent neural networks (RNNs) architecture. Progress on the topic of deep learning includes successful adaptations of deep versions of these architectures. In this study, a new model for deep bidirectional LSTM network-based wavelet sequences called DBLSTM-WS was proposed for classifying electrocardiogram (ECG) signals. For this purpose, a new wavelet-based layer is implemented to generate ECG signal sequences. The ECG signals were decomposed into frequency sub-bands at different scales in this layer. These sub-bands are used as sequences for the input of LSTM networks. New network models that include unidirectional (ULSTM) and bidirectional (BLSTM) structures are designed for performance comparisons. Experimental studies have been performed for five different types of heartbeats obtained from the MIT-BIH arrhythmia database. These five types are Normal Sinus Rhythm (NSR), Ventricular Premature Contraction (VPC), Paced Beat (PB), Left Bundle Branch Block (LBBB), and Right Bundle Branch Block (RBBB). The results show that the DBLSTM-WS model gives a high recognition performance of 99.39 . It has been observed that the wavelet-based layer proposed in the study significantly improves the recognition performance of conventional networks. This proposed network structure is an important approach that can be applied to similar signal processing problems. Recent studies suggest that deep Convolutional Neural Network (CNN) models show higher representational similarity, compared to any other existing object recognition models, with macaque inferior temporal (IT) cortical responses, human ventral stream fMRI activations and human object recognition. These studies employed natural images of objects. A long research tradition employed abstract shapes to probe the selectivity of IT neurons. If CNN models provide a realistic model of IT responses, then they should capture the IT selectivity for such shapes. Here, we compare the activations of CNN units to a stimulus set of 2D regular and irregular shapes with the response selectivity of macaque IT neurons and with human similarity judgements. The shape set consisted of regular shapes that differed in nonaccidental properties, and irregular, asymmetrical shapes with curved or straight boundaries. We found that deep CNNs (Alexnet, VGG-16 and VGG-19) that were trained to classify natural images show response modulations to these shapes that were similar to those of IT neurons. Untrained CNNs with the same architecture than trained CNNs, but with random weights, demonstrated a poorer similarity than CNNs trained in classification. The difference between the trained and untrained CNNs emerged at the deep convolutional layers, where the similarity between the shape-related response modulations of IT neurons and the trained CNNs was high. Unlike IT neurons, human similarity judgements of the same shapes correlated best with the last layers of the trained CNNs. In particular, these deepest layers showed an enhanced sensitivity for straight versus curved irregular shapes, similar to that shown in human shape judgments. In conclusion, the representations of abstract shape similarity are highly comparable between macaque IT neurons and deep convolutional layers of CNNs that were trained to classify natural images, while human shape similarity judgments correlate better with the deepest layers. We trained a large, deep convolutional neural network to classify the 1.2 million high-resolution images in the ImageNet LSVRC-2010 contest into the 1000 different classes. On the test data, we achieved top-1 and top-5 error rates of 37.5 and 17.0 , respectively, which is considerably better than the previous state-of-the-art. The neural network, which has 60 million parameters and 650,000 neurons, consists of five convolutional layers, some of which are followed by max-pooling layers, and three fully connected layers with a final 1000-way softmax. To make training faster, we used non-saturating neurons and a very efficient GPU implementation of the convolution operation. To reduce overfitting in the fully connected layers we employed a recently developed regularization method called "dropout" that proved to be very effective. We also entered a variant of this model in the ILSVRC-2012 competition and achieved a winning top-5 test error rate of 15.3 , compared to 26.2 achieved by the second-best entry. Convolutional Neural Networks (CNNs) can be shifted across 2D images or 3D videos to segment them. They have a fixed input size and typically perceive only small local contexts of the pixels to be classified as foreground or background. In contrast, Multi-Dimensional Recurrent NNs (MD-RNNs) can perceive the entire spatio-temporal context of each pixel in a few sweeps through all pixels, especially when the RNN is a Long Short-Term Memory (LSTM). Despite these theoretical advantages, however, unlike CNNs, previous MD-LSTM variants were hard to parallelize on GPUs. Here we re-arrange the traditional cuboid order of computations in MD-LSTM in pyramidal fashion. The resulting PyraMiD-LSTM is easy to parallelize, especially for 3D data such as stacks of brain slice images. PyraMiD-LSTM achieved best known pixel-wise brain image segmentation results on MRBrainS13 (and competitive results on EM-ISBI12). In this paper, a novel architecture for a deep recurrent neural network, residual LSTM is introduced. A plain LSTM has an internal memory cell that can learn long term dependencies of sequential data. It also provides a temporal shortcut path to avoid vanishing or exploding gradients in the temporal domain. The residual LSTM provides an additional spatial shortcut path from lower layers for efficient training of deep networks with multiple LSTM layers. Compared with the previous work, highway LSTM, residual LSTM separates a spatial shortcut path with temporal one by using output layers, which can help to avoid a conflict between spatial and temporal-domain gradient flows. Furthermore, residual LSTM reuses the output projection matrix and the output gate of LSTM to control the spatial information flow instead of additional gate networks, which effectively reduces more than 10 of network parameters. An experiment for distant speech recognition on the AMI SDM corpus shows that 10-layer plain and highway LSTM networks presented 13.7 and 6.2 increase in WER over 3-layer aselines, respectively. On the contrary, 10-layer residual LSTM networks provided the lowest WER 41.0 , which corresponds to 3.3 and 2.8 WER reduction over plain and highway LSTM networks, respectively. In this paper, we propose a novel two-stream framework based on combinational deep neural networks. The framework is mainly composed of two components: one is a parallel two-stream encoding component which learns video encoding from multiple sources using 3D convolutional neural networks and the other is a long-short-term-memory (LSTM)-based decoding language model which transfers the input encoded video representations to text descriptions. The merits of our proposed model are: 1) It extracts both temporal and spatial features by exploring the usage of 3D convolutional networks on both raw RGB frames and motion history images. 2) Our model can dynamically tune the weights of different feature channels since the network is trained end-to-end from learning combinational encoding of multiple features to LSTM-based language model. Our model is evaluated on three public video description datasets: one YouTube clips dataset (Microsoft Video Description Corpus) and two large movie description datasets (MPII Corpus and Montreal Video Annotation Dataset) and achieves comparable or better performance than the state-of-the-art approaches in video caption generation. Multivariate techniques based on engineered features have found wide adoption in the identification of jets resulting from hadronic top decays at the Large Hadron Collider (LHC). Recent Deep Learning developments in this area include the treatment of the calorimeter activation as an image or supplying a list of jet constituent momenta to a fully connected network. This latter approach lends itself well to the use of Recurrent Neural Networks. In this work the applicability of architectures incorporating Long Short-Term Memory (LSTM) networks is explored. Several network architectures, methods of ordering of jet constituents, and input pre-processing are studied. The best performing LSTM network achieves a background rejection of 100 for 50 signal efficiency. This represents more than a factor of two improvement over a fully connected Deep Neural Network (DNN) trained on similar types of inputs. Neural network models have been demonstrated to be capable of achieving remarkable performance in sentence and document modeling. Convolutional neural network (CNN) and recurrent neural network (RNN) are two mainstream architectures for such modeling tasks, which adopt totally different ways of understanding natural languages. In this work, we combine the strengths of both architectures and propose a novel and unified model called C-LSTM for sentence representation and text classification. C-LSTM utilizes CNN to extract a sequence of higher-level phrase representations, and are fed into a long short-term memory recurrent neural network (LSTM) to obtain the sentence representation. C-LSTM is able to capture both local features of phrases as well as global and temporal sentence semantics. We evaluate the proposed architecture on sentiment classification and question classification tasks. The experimental results show that the C-LSTM outperforms both CNN and LSTM and can achieve excellent performance on these tasks. Deep neural network is difficult to train and this predicament becomes worse as the depth increases. The essence of this problem exists in the magnitude of backpropagated errors that will result in gradient vanishing or exploding phenomenon. We show that a variant of regularizer which utilizes orthonormality among different filter banks can alleviate this problem. Moreover, we design a backward error modulation mechanism based on the quasi-isometry assumption between two consecutive parametric layers. Equipped with these two ingredients, we propose several novel optimization solutions that can be utilized for training a specific-structured (repetitively triple modules of Conv-BNReLU) extremely deep convolutional neural network (CNN) WITHOUT any shortcuts identity mappings from scratch. Experiments show that our proposed solutions can achieve distinct improvements for a 44-layer and a 110-layer plain networks on both the CIFAR-10 and ImageNet datasets. Moreover, we can successfully train plain CNNs to match the performance of the residual counterparts. Besides, we propose new principles for designing network structure from the insights evoked by orthonormality. Combined with residual structure, we achieve comparative performance on the ImageNet dataset. Deep neural network is difficult to train and this predicament becomes worse as the depth increases. The essence of this problem exists in the magnitude of backpropagated errors that will result in gradient vanishing or exploding phenomenon. We show that a variant of regularizer which utilizes orthonormality among different filter banks can alleviate this problem. Moreover, we design a backward error modulation mechanism based on the quasi-isometry assumption between two consecutive parametric layers. Equipped with these two ingredients, we propose several novel optimization solutions that can be utilized for training a specific-structured (repetitively triple modules of Conv-BNReLU) extremely deep convolutional neural network (CNN) WITHOUT any shortcuts identity mappings from scratch. Experiments show that our proposed solutions can achieve distinct improvements for a 44-layer and a 110-layer plain networks on both the CIFAR-10 and ImageNet datasets. Moreover, we can successfully train plain CNNs to match the performance of the residual counterparts. Besides, we propose new principles for designing network structure from the insights evoked by orthonormality. Combined with residual structure, we achieve comparative performance on the ImageNet dataset. While deep convolutional neural networks (CNN) have been successfully applied for 2D image analysis, it is still challenging to apply them to 3D anisotropic volumes, especially when the within-slice resolution is much higher than the between-slice resolution and when the amount of 3D volumes is relatively small. On one hand, direct learning of CNN with 3D convolution kernels suffers from the lack of data and likely ends up with poor generalization; insufficient GPU memory limits the model size or representational power. On the other hand, applying 2D CNN with generalizable features to 2D slices ignores between-slice information. Coupling 2D network with LSTM to further handle the between-slice information is not optimal due to the difficulty in LSTM learning. To overcome the above challenges, we propose a 3D Anisotropic Hybrid Network (AH-Net) that transfers convolutional features learned from 2D images to 3D anisotropic volumes. Such a transfer inherits the desired strong generalization capability for within-slice information while naturally exploiting between-slice information for more effective modelling. The focal loss is further utilized for more effective end-to-end learning. We experiment with the proposed 3D AH-Net on two different medical image analysis tasks, namely lesion detection from a Digital Breast Tomosynthesis volume, and liver and liver tumor segmentation from a Computed Tomography volume and obtain the state-of-the-art results. Convolutional neural networks (CNNs) have achieved remarkable performance in a wide range of computer vision tasks, typically at the cost of massive computational complexity. The low speed of these networks may hinder real-time applications especially when computational resources are limited. In this paper, an efficient and effective approach is proposed to accelerate the test-phase computation of CNNs based on low-rank and group sparse tensor decomposition. Specifically, for each convolutional layer, the kernel tensor is decomposed into the sum of a small number of low multilinear rank tensors. Then we replace the original kernel tensors in all layers with the approximate tensors and fine-tune the whole net with respect to the final classification task using standard backpropagation. Comprehensive experiments on ILSVRC-12 demonstrate significant reduction in computational complexity, at the cost of negligible loss in accuracy. For the widely used VGG-16 model, our approach obtains a 6.6 @math speed-up on PC and 5.91 @math speed-up on mobile device of the whole network with less than 1 increase on top-5 error. Machine learning algorithms based on deep neural networks have achieved remarkable results and are being extensively used in different domains. However, the machine learning algorithms requires access to raw data which is often privacy sensitive. To address this issue, we develop new techniques to provide solutions for running deep neural networks over encrypted data. In this paper, we develop new techniques to adopt deep neural networks within the practical limitation of current homomorphic encryption schemes. More specifically, we focus on classification of the well-known convolutional neural networks (CNN). First, we design methods for approximation of the activation functions commonly used in CNNs (i.e. ReLU, Sigmoid, and Tanh) with low degree polynomials which is essential for efficient homomorphic encryption schemes. Then, we train convolutional neural networks with the approximation polynomials instead of original activation functions and analyze the performance of the models. Finally, we implement convolutional neural networks over encrypted data and measure performance of the models. Our experimental results validate the soundness of our approach with several convolutional neural networks with varying number of layers and structures. When applied to the MNIST optical character recognition tasks, our approach achieves 99.52 accuracy which significantly outperforms the state-of-the-art solutions and is very close to the accuracy of the best non-private version, 99.77 . Also, it can make close to 164000 predictions per hour. We also applied our approach to CIFAR-10, which is much more complex compared to MNIST, and were able to achieve 91.5 accuracy with approximation polynomials used as activation functions. These results show that CryptoDL provides efficient, accurate and scalable privacy-preserving predictions. Neural network based approaches have recently produced record-setting performances in natural language understanding tasks such as word labeling. In the word labeling task, a tagger is used to assign a label to each word in an input sequence. Specifically, simple recurrent neural networks (RNNs) and convolutional neural networks (CNNs) have shown to significantly outperform the previous state-of-the-art - conditional random fields (CRFs). This paper investigates using long short-term memory (LSTM) neural networks, which contain input, output and forgetting gates and are more advanced than simple RNN, for the word labeling task. To explicitly model output-label dependence, we propose a regression model on top of the LSTM un-normalized scores. We also propose to apply deep LSTM to the task. We investigated the relative importance of each gate in the LSTM by setting other gates to a constant and only learning particular gates. Experiments on the ATIS dataset validated the effectiveness of the proposed models. Deep Convolutional Neural Networks (CNNs) offer remarkable performance of classifications and regressions in many high-dimensional problems and have been widely utilized in real-word cognitive applications. However, high computational cost of CNNs greatly hinder their deployment in resource-constrained applications, real-time systems and edge computing platforms. To overcome this challenge, we propose a novel filter-pruning framework, two-phase filter pruning based on conditional entropy, namely , to compress the CNN models and reduce the inference time with marginal performance degradation. In our proposed method, we formulate filter pruning process as an optimization problem and propose a novel filter selection criteria measured by conditional entropy. Based on the assumption that the representation of neurons shall be evenly distributed, we also develop a maximum-entropy filter freeze technique that can reduce over fitting. Two filter pruning strategies -- global and layer-wise strategies, are compared. Our experiment result shows that combining these two strategies can achieve a higher neural network compression ratio than applying only one of them under the same accuracy drop threshold. Two-phase pruning, that is, combining both global and layer-wise strategies, achieves 10 X FLOPs reduction and 46 inference time reduction on VGG-16, with 2 accuracy drop. To attain a favorable performance on large-scale datasets, convolutional neural networks (CNNs) are usually designed to have very high capacity involving millions of parameters. In this work, we aim at optimizing the number of neurons in a network, thus the number of parameters. We show that, by incorporating sparse constraints into the objective function, it is possible to decimate the number of neurons during the training stage. As a result, the number of parameters and the memory footprint of the neural network are also reduced, which is also desirable at the test time. We evaluated our method on several well-known CNN structures including AlexNet, and VGG over different datasets including ImageNet. Extensive experimental results demonstrate that our method leads to compact networks. Taking first fully connected layer as an example, our compact CNN contains only (30 , ) of the original neurons without any degradation of the top-1 classification accuracy. For the past decade, convolutional networks have been used for 3D reconstruction of neurons from electron microscopic (EM) brain images. Recent years have seen great improvements in accuracy, as evidenced by submissions to the SNEMI3D benchmark challenge. Here we report the first submission to surpass the estimate of human accuracy provided by the SNEMI3D leaderboard. A variant of 3D U-Net is trained on a primary task of predicting affinities between nearest neighbor voxels, and an auxiliary task of predicting long-range affinities. The training data is augmented by simulated image defects. The nearest neighbor affinities are used to create an oversegmentation, and then supervoxels are greedily agglomerated based on mean affinity. The resulting SNEMI3D score exceeds the estimate of human accuracy by a large margin. While one should be cautious about extrapolating from the SNEMI3D benchmark to real-world accuracy of large-scale neural circuit reconstruction, our result inspires optimism that the goal of full automation may be realizable in the future.