The use of Association Rule Mining techniques in diverse contexts and domains has resulted in the creation of numerous interestingness measures. This, in turn, has motivated researchers to come up with various classification schemes for these measures. One popular approach to classify the objective measures is to assess the set of mathematical properties they satisfy in order to help practitioners select the right measure for a given problem. In this research, we discuss the insufficiency of the existing properties in literature to capture certain behaviors of interestingness measures. This motivates us to present a novel approach to analyze and classify measures. We refer to this as a rate of change analysis (RCA). In this analysis a measure is described by how it varies if there is a unit change in the frequency count @math , for different pre-existing states of the frequency counts. More formally, we look at the first partial derivative of the measure with respect to the various frequency count variables. We then use this analysis to define two new properties, Unit-Null Asymptotic Invariance (UNAI) and Unit-Null Zero Rate (UNZR). UNAI looks at the asymptotic effect of adding frequency patterns, while UNZR looks at the initial effect of adding frequency patterns when they do not pre-exist in the dataset. We present a comprehensive analysis of 50 interestingness measures and classify them in accordance with the two properties. We also present empirical studies, involving both synthetic and real-world datasets, which are used to cluster various measures according to the rule ranking patterns of the measures. The study concludes with the observation that classification of measures using the empirical clusters share significant similarities to the classification of measures done through the properties presented in this research.
A large number of objective IMs have emerged as a result of the application of ARM across different domains. It is also documented that not all measures are capable of capturing the strength of associations and in some cases provide conflicting information of the strength of patterns @cite_7 . Given the abundance of measures and difficulty in choosing the appropriate IM, researchers have suggested various classification schemes (of the IMs) to help identify the appropriate measure for a given application @cite_1 , @cite_7 , @cite_9 , @cite_13 , @cite_8 , @cite_2 . There are two different types of classification that exist in literature: classification based on the properties of IMs (e.g. @cite_1 , @cite_7 , @cite_9 , @cite_13 ) and classification based on empirical results of IMs on different datasets (e.g. @cite_8 ).
@cite_7 @cite_8 @cite_9 @cite_1 @cite_2 @cite_13
2000292092 2522876520 2066277072 2126975755 1973036367 2124710650 2785994509 2017562693 2103231373 2837911466 2962743311 2603093240 2963876058 2202499615 2129367118 1520257903 2117169652 1808652302 2468923260 2125150859
Many machine learning and pattern classification methods have been applied to the diagnosis of Alzheimer’s disease (AD) and its prodromal stage, i.e., mild cognitive impairment (MCI). Recently, rather than predicting categorical variables as in classification, several pattern regression methods have also been used to estimate continuous clinical variables from brain images. However, most existing regression methods focus on estimating multiple clinical variables separately and thus cannot utilize the intrinsic useful correlation information among different clinical variables. On the other hand, in those regression methods, only a single modality of data (usually only the structural MRI) is often used, without considering the complementary information that can be provided by different modalities. In this paper, we propose a general methodology, namely Multi-Modal Multi-Task (M3T) learning, to jointly predict multiple variables from multi-modal data. Here, the variables include not only the clinical variables used for regression but also the categorical variable used for classification, with different tasks corresponding to prediction of different variables. Specifically, our method contains two key components, i.e., (1) a multi-task feature selection which selects the common subset of relevant features for multiple variables from each modality, and (2) a multi-modal support vector machine which fuses the above-selected features from all modalities to predict multiple (regression and classification) variables. To validate our method, we perform two sets of experiments on ADNI baseline MRI, FDG-PET, and cerebrospinal fluid (CSF) data from 45 AD patients, 91 MCI patients, and 50 healthy controls (HC). In the first set of experiments, we estimate two clinical variables such as Mini Mental State Examination (MMSE) and Alzheimer’s Disease Assessment Scale - Cognitive Subscale (ADAS-Cog), as well as one categorical variable (with value of ‘AD’, ‘MCI’ or ‘HC’), from the baseline MRI, FDG-PET, and CSF data. In the second set of experiments, we predict the 2-year changes of MMSE and ADAS-Cog scores and also the conversion of MCI to AD from the baseline MRI, FDG-PET, and CSF data. The results on both sets of experiments demonstrate that our proposed M3T learning scheme can achieve better performance on both regression and classification tasks than the conventional learning methods. We explore if and how Microsoft Academic (MA) could be used for bibliometric analyses. First, we examine the Academic Knowledge API (AK API), an interface to access MA data, and compare it to Google Scholar (GS). Second, we perform a comparative citation analysis of researchers by normalizing data from MA and Scopus. We find that MA offers structured and rich metadata, which facilitates data retrieval, handling and processing. In addition, the AK API allows retrieving frequency distributions of citations. We consider these features to be a major advantage of MA over GS. However, we identify four main limitations regarding the available metadata. First, MA does not provide the document type of a publication. Second, the "fields of study" are dynamic, too specific and field hierarchies are incoherent. Third, some publications are assigned to incorrect years. Fourth, the metadata of some publications did not include all authors. Nevertheless, we show that an average-based indicator (i.e. the journal normalized citation score; JNCS) as well as a distribution-based indicator (i.e. percentile rank classes; PR classes) can be calculated with relative ease using MA. Hence, normalization of citation counts is feasible with MA. The citation analyses in MA and Scopus yield uniform results. The JNCS and the PR classes are similar in both databases, and, as a consequence, the evaluation of the researchers' publication impact is congruent in MA and Scopus. Given the fast development in the last year, we postulate that MA has the potential to be used for full-fledged bibliometric analyses. Many techniques for association rule mining and feature selection require a suitable metric to capture the dependencies among variables in a data set. For example, metrics such as support, confidence, lift, correlation, and collective strength are often used to determine the interestingness of association patterns. However, many such measures provide conflicting information about the interestingness of a pattern, and the best metric to use for a given application domain is rarely known. In this paper, we present an overview of various measures proposed in the statistics, machine learning and data mining literature. We describe several key properties one should examine in order to select the right measure for a given application domain. A comparative study of these properties is made using twenty one of the existing measures. We show that each measure has different properties which make them useful for some application domains, but not for others. We also present two scenarios in which most of the existing measures agree with each other, namely, support-based pruning and table standardization. Finally, we present an algorithm to select a small set of tables such that an expert can select a desirable measure by looking at just this small set of tables. Objective A system that translates narrative text in the medical domain into structured representation is in great demand. The system performs three sub-tasks: concept extraction, assertion classification, and relation identification. @PARASPLIT Design The overall system consists of five steps: (1) pre-processing sentences, (2) marking noun phrases (NPs) and adjective phrases (APs), (3) extracting concepts that use a dosage-unit dictionary to dynamically switch two models based on Conditional Random Fields (CRF), (4) classifying assertions based on voting of five classifiers, and (5) identifying relations using normalized sentences with a set of effective discriminating features. @PARASPLIT Measurements Macro-averaged and micro-averaged precision, recall and F-measure were used to evaluate results. @PARASPLIT Results The performance is competitive with the state-of-the-art systems with micro-averaged F-measure of 0.8489 for concept extraction, 0.9392 for assertion classification and 0.7326 for relation identification. @PARASPLIT Conclusions The system exploits an array of common features and achieves state-of-the-art performance. Prudent feature engineering sets the foundation of our systems. In concept extraction, we demonstrated that switching models, one of which is especially designed for telegraphic sentences, improved extraction of the treatment concept significantly. In assertion classification, a set of features derived from a rule-based classifier were proven to be effective for the classes such as conditional and possible. These classes would suffer from data scarcity in conventional machine-learning methods. In relation identification, we use two-staged architecture, the second of which applies pairwise classifiers to possible candidate classes. This architecture significantly improves performance. Objective measures such as support, confidence, interest factor, correlation, and entropy are often used to evaluate the interestingness of association patterns. However, in many situations, these measures may provide conflicting information about the interestingness of a pattern. Data mining practitioners also tend to apply an objective measure without realizing that there may be better alternatives available for their application. In this paper, we describe several key properties one should examine in order to select the right measure for a given application. A comparative study of these properties is made using twenty-one measures that were originally developed in diverse fields such as statistics, social science, machine learning, and data mining. We show that depending on its properties, each measure is useful for some application, but not for others. We also demonstrate two scenarios in which many existing measures become consistent with each other, namely, when support-based pruning and a technique known as table standardization are applied. Finally, we present an algorithm for selecting a small set of patterns such that domain experts can find a measure that best fits their requirements by ranking this small set of patterns. Classification with imbalanced datasets supposes a new challenge for researches in the framework of machine learning. This problem appears when the number of patterns that represents one of the classes of the dataset (usually the concept of interest) is much lower than in the remaining classes. Thus, the learning model must be adapted to this situation, which is very common in real applications. In this paper, a dynamic over-sampling procedure is proposed for improving the classification of imbalanced datasets with more than two classes. This procedure is incorporated into a memetic algorithm (MA) that optimizes radial basis functions neural networks (RBFNNs). To handle class imbalance, the training data are resampled in two stages. In the first stage, an over-sampling procedure is applied to the minority class to balance in part the size of the classes. Then, the MA is run and the data are over-sampled in different generations of the evolution, generating new patterns of the minimum sensitivity class (the class with the worst accuracy for the best RBFNN of the population). The methodology proposed is tested using 13 imbalanced benchmark classification datasets from well-known machine learning problems and one complex problem of microbial growth. It is compared to other neural network methods specifically designed for handling imbalanced data. These methods include different over-sampling procedures in the preprocessing stage, a threshold-moving method where the output threshold is moved toward inexpensive classes and ensembles approaches combining the models obtained with these techniques. The results show that our proposal is able to improve the sensitivity in the generalization set and obtains both a high accuracy level and a good classification level for each class. Many text classification tasks are known to be highly domain-dependent. Unfortunately, the availability of training data can vary drastically across domains. Worse still, for some domains there may not be any annotated data at all. In this work, we propose a multinomial adversarial network (MAN) to tackle the text classification problem in this real-world multidomain setting (MDTC). We provide theoretical justifications for the MAN framework, proving that different instances of MANs are essentially minimizers of various f-divergence metrics (Ali and Silvey, 1966) among multiple probability distributions. MANs are thus a theoretically sound generalization of traditional adversarial networks that discriminate over two distributions. More specifically, for the MDTC task, MAN learns features that are invariant across multiple domains by resorting to its ability to reduce the divergence among the feature distributions of each domain. We present experimental results showing that MANs significantly outperform the prior art on the MDTC task. We also show that MANs achieve state-of-the-art performance for domains with no labeled data. In the past several years studies have started to appear comparing the accuracies of various science mapping approaches. These studies primarily compare the cluster solutions resulting from different similarity approaches, and give varying results. In this study we compare the accuracies of cluster solutions of a large corpus of 2,153,769 recent articles from the biomedical literature (2004–2008) using four similarity approaches: co-citation analysis, bibliographic coupling, direct citation, and a bibliographic coupling-based citation-text hybrid approach. Each of the four approaches can be considered a way to represent the research front in biomedicine, and each is able to successfully cluster over 92p of the corpus. Accuracies are compared using two metrics—within-cluster textual coherence as defined by the Jensen-Shannon divergence, and a concentration measure based on the grant-to-article linkages indexed in MEDLINE. Of the three pure citation-based approaches, bibliographic coupling slightly outperforms co-citation analysis using both accuracy measures; direct citation is the least accurate mapping approach by far. The hybrid approach improves upon the bibliographic coupling results in all respects. We consider the results of this study to be robust given the very large size of the corpus, and the specificity of the accuracy measures used. © 2010 Wiley Periodicals, Inc. The use of statistical AI techniques in authorship recognition (or stylometry) has contributed to literary and historical breakthroughs. These successes have led to the use of these techniques in criminal investigations and prosecutions. However, few have studied adversarial attacks and their devastating effect on the robustness of existing classification methods. This paper presents a framework for adversarial attacks including obfuscation attacks, where a subject attempts to hide their identity imitation attacks, where a subject attempts to frame another subject by imitating their writing style. The major contribution of this research is that it demonstrates that both attacks work very well. The obfuscation attack reduces the effectiveness of the techniques to the level of random guessing and the imitation attack succeeds with 68-91 probability depending on the stylometric technique used. These results are made more significant by the fact that the experimental subjects were unfamiliar with stylometric techniques, without specialized knowledge in linguistics, and spent little time on the attacks. This paper also provides another significant contribution to the field in using human subjects to empirically validate the claim of high accuracy for current techniques (without attacks) by reproducing results for three representative stylometric methods. Modern cyber attacks consist of a series of steps and are generally part of larger campaigns. Large-scale field data provides a quantitative measurement of these campaigns. On the other hand, security practitioners extract and report qualitative campaign characteristics manually. Linking the two sources provides new insights about attacker strategies from measurements. However, this is a time-consuming task because qualitative measurements are generally reported in natural language and are not machine-readable. We propose an approach to bridge measurement data with manual analysis. We borrow the idea from threat intelligence: we define campaigns using a 4-stage model, and describe each stage using IOCs (indicators of compromise), e.g. URLs and IP addresses. We train a multi-class classifier to extract IOCs and further categorize them into different stages. We implement these ideas in a system called ChainSmith. Our system can achieve 91.9 precision and 97.8 recall in extracting IOCs, and can determine the campaign roles for 86.2 of IOCs with 78.2 precision and 80.7 recall. We run ChainSmith on 14,155 online security articles, from which we collect 24,653 IOCs. The semantic roles allow us to link manual attack analysis with large scale field measurements. In particular, we study the effectiveness of different persuasion techniques used on enticing user to download the payloads. We find that the campaign usually starts from social engineering and "missing codec" ruse is a common persuasion technique that generates the most suspicious downloads each day. Motivated by applications in computational advertising and systems biology, we consider the problem of identifying the best out of several possible soft interventions at a source node @math in an acyclic causal directed graph, to maximize the expected value of a target node @math (located downstream of @math ). Our setting imposes a fixed total budget for sampling under various interventions, along with cost constraints on different types of interventions. We pose this as a best arm identification bandit problem with @math arms where each arm is a soft intervention at @math and leverage the information leakage among the arms to provide the first gap dependent error and simple regret bounds for this problem. Our results are a significant improvement over the traditional best arm identification results. We empirically show that our algorithms outperform the state of the art in the Flow Cytometry data-set, and also apply our algorithm for model interpretation of the Inception-v3 deep net that classifies images. Motivated by applications in computational advertising and systems biology, we consider the problem of identifying the best out of several possible soft interventions at a source node V in an acyclic causal directed graph, to maximize the expected value of a target node Y (located downstream of V). Our setting imposes a fixed total budget for sampling under various interventions, along with cost constraints on different types of interventions. We pose this as a best arm identification bandit problem with K arms where each arm is a soft intervention at V, and leverage the information leakage among the arms to provide the first gap dependent error and simple regret bounds for this problem. Our results are a significant improvement over the traditional best arm identification results. We empirically show that our algorithms outperform the state of the art in the Flow Cytometry data-set, and also apply our algorithm for model interpretation of the Inception-v3 deep net that classifies images. Class labels have been empirically shown useful in improving the sample quality of generative adversarial nets (GANs). In this paper, we mathematically study the properties of the current variants of GANs that make use of class label information. With class aware gradient and cross-entropy decomposition, we reveal how class labels and associated losses influence GAN's training. Based on that, we propose Activation Maximization Generative Adversarial Networks (AM-GAN) as an advanced solution. Comprehensive experiments have been conducted to validate our analysis and evaluate the effectiveness of our solution, where AM-GAN outperforms other strong baselines and achieves state-of-the-art Inception Score (8.91) on CIFAR-10. In addition, we demonstrate that, with the Inception ImageNet classifier, Inception Score mainly tracks the diversity of the generator, and there is, however, no reliable evidence that it can reflect the true sample quality. We thus propose a new metric, called AM Score, to provide more accurate estimation on the sample quality. Our proposed model also outperforms the baseline methods in the new metric. In the context of fine-grained visual categorization, the ability to interpret models as human-understandable visual manuals is sometimes as important as achieving high classification accuracy. In this paper, we propose a novel Part-Stacked CNN architecture that explicitly explains the finegrained recognition process by modeling subtle differences from object parts. Based on manually-labeled strong part annotations, the proposed architecture consists of a fully convolutional network to locate multiple object parts and a two-stream classification network that encodes object-level and part-level cues simultaneously. By adopting a set of sharing strategies between the computation of multiple object parts, the proposed architecture is very efficient running at 20 frames sec during inference. Experimental results on the CUB-200-2011 dataset reveal the effectiveness of the proposed architecture, from multiple perspectives of classification accuracy, model interpretability, and efficiency. Being able to provide interpretable recognition results in realtime, the proposed method is believed to be effective in practical applications. Objective A supervised machine learning approach to discover relations between medical problems, treatments, and tests mentioned in electronic medical records. @PARASPLIT Materials and methods A single support vector machine classifier was used to identify relations between concepts and to assign their semantic type. Several resources such as Wikipedia, WordNet, General Inquirer, and a relation similarity metric inform the classifier. @PARASPLIT Results The techniques reported in this paper were evaluated in the 2010 i2b2 Challenge and obtained the highest F1 score for the relation extraction task. When gold standard data for concepts and assertions were available, F1 was 73.7, precision was 72.0, and recall was 75.3. F1 is defined as 2 *Precision *Recall (Precision+Recall). Alternatively, when concepts and assertions were discovered automatically, F1 was 48.4, precision was 57.6, and recall was 41.7. @PARASPLIT Discussion Although a rich set of features was developed for the classifiers presented in this paper, little knowledge mining was performed from medical ontologies such as those found in UMLS. Future studies should incorporate features extracted from such knowledge sources, which we expect to further improve the results. Moreover, each relation discovery was treated independently. Joint classification of relations may further improve the quality of results. Also, joint learning of the discovery of concepts, assertions, and relations may also improve the results of automatic relation extraction. @PARASPLIT Conclusion Lexical and contextual features proved to be very important in relation extraction from medical texts. When they are not available to the classifier, the F1 score decreases by 3.7 . In addition, features based on similarity contribute to a decrease of 1.1 when they are not available. Finding interesting association rules is an important and active research field in data mining. The algorithms of the Apriori family are based on two rule extraction measures, support and confidence. Although these two measures have the virtue of being algorithmically fast, they generate a prohibitive number of rules most of which are redundant and irrelevant. It is therefore necessary to use further measures which filter uninteresting rules. Many synthesis studies were then realized on the interestingness measures according to several points of view. Different reported studies have been carried out to identify "good" properties of rule extraction measures and these properties have been assessed on 61 measures. The purpose of this paper is twofold. First to extend the number of the measures and properties to be studied, in addition to the formalization of the properties proposed in the literature. Second, in the light of this formal study, to categorize the studied measures. This paper leads then to identify categories of measures in order to help the users to efficiently select an appropriate measure by choosing one or more measure(s) during the knowledge extraction process. The properties evaluation on the 61 measures has enabled us to identify 7 classes of measures, classes that we obtained using two different clustering techniques. The application of frequent patterns in classification appeared in sporadic studies and achieved initial success in the classification of relational data, text documents and graphs. In this paper, we conduct a systematic exploration of frequent pattern-based classification, and provide solid reasons supporting this methodology. It was well known that feature combinations (patterns) could capture more underlying semantics than single features. However, inclusion of infrequent patterns may not significantly improve the accuracy due to their limited predictive power. By building a connection between pattern frequency and discriminative measures such as information gain and Fisher score, we develop a strategy to set minimum support in frequent pattern mining for generating useful patterns. Based on this strategy, coupled with a proposed feature selection algorithm, discriminative frequent patterns can be generated for building high quality classifiers. We demonstrate that the frequent pattern-based classification framework can achieve good scalability and high accuracy in classifying large datasets. Empirical studies indicate that significant improvement in classification accuracy is achieved (up to 12 in UCI datasets) using the so-selected discriminative frequent patterns. Objective To summarize literature describing approaches aimed at automatically identifying patients with a common phenotype. @PARASPLIT Materials and methods We performed a review of studies describing systems or reporting techniques developed for identifying cohorts of patients with specific phenotypes. Every full text article published in (1) Journal of American Medical Informatics Association , (2) Journal of Biomedical Informatics , (3) Proceedings of the Annual American Medical Informatics Association Symposium , and (4) Proceedings of Clinical Research Informatics Conference within the past 3 years was assessed for inclusion in the review. Only articles using automated techniques were included. @PARASPLIT Results Ninety-seven articles met our inclusion criteria. Forty-six used natural language processing (NLP)-based techniques, 24 described rule-based systems, 41 used statistical analyses, data mining, or machine learning techniques, while 22 described hybrid systems. Nine articles described the architecture of large-scale systems developed for determining cohort eligibility of patients. @PARASPLIT Discussion We observe that there is a rise in the number of studies associated with cohort identification using electronic medical records. Statistical analyses or machine learning, followed by NLP techniques, are gaining popularity over the years in comparison with rule-based systems. @PARASPLIT Conclusions There are a variety of approaches for classifying patients into a particular phenotype. Different techniques and data sources are used, and good performance is reported on datasets at respective institutions. However, no system makes comprehensive use of electronic medical records addressing all of their known weaknesses. Existing billion-scale nearest neighbor search systems have mostly been compared on a single dataset of a billion of SIFT vectors, where systems based on the Inverted Multi-Index (IMI) have been performing very well, achieving state-of-the-art recall in several milliseconds. SIFT-like descriptors, however, are quickly being replaced with descriptors based on deep neural networks (DNN) that provide better performance for many computer vision tasks. In this paper, we introduce a new dataset of one billion descriptors based on DNNs and reveal the relative inefficiency of IMI-based indexing for such descriptors compared to SIFT data. We then introduce two new indexing structures, the Non-Orthogonal Inverted Multi-Index (NO-IMI) and the Generalized Non-Orthogonal Inverted Multi-Index (GNO-IMI). We show that due to additional flexibility, the new structures are able to adapt to DNN descriptor distribution in a better way. In particular, extensive experiments on the new dataset demonstrate that these data structures provide considerably better trade-off between the speed of retrieval and recall, given similar amount of memory, as compared to the standard Inverted Multi-Index. In general in an organisation whose system of governance involves weighted voting, a member's weight in terms of the number of votes and the formal power it represents differ. Power indices provide a means of analysing this difference. The paper uses new algorithms for computing power indices for large games. Three analyses are carried out: (1) the distribution of Banzhaf voting power among members in 1999; the results show that the United States has considerably more power over ordinary decisions than its weight of 17 but that the use of special supermajorities limits its power; (2) the effect of varying the majority requirement on the power of the IMF to act and the powers of members to prevent and initiate action (Coleman indices); the results show the effect of supermajorities severely limits the power to act and therefore renders the voting system ineffective in democratic terms, also the sovereignty of the United States within the IMF is effectively limited to just the power of veto; (3) the paper proposes the determination of the weights instrumentally by means of an iterative algorithm to give the required power distribution; this would be a useful procedure for determining appropriate changes in weights consequent on changes to individual countries' quotas; this is applied to the 1999 data. Policy recommendations are, first, that the IMF use only simple majority voting, and discontinue using special supermajorities, and, second, allocate voting weight instrumentally using power indices.