The motivation for this paper is to apply Bayesian structure learning using Model Averaging in large-scale networks. Currently, Bayesian model averaging algorithm is applicable to networks with only tens of variables, restrained by its super-exponential complexity. We present a novel framework, called LSBN(Large-Scale Bayesian Network), making it possible to handle networks with infinite size by following the principle of divide-and-conquer. The method of LSBN comprises three steps. In general, LSBN first performs the partition by using a second-order partition strategy, which achieves more robust results. LSBN conducts sampling and structure learning within each overlapping community after the community is isolated from other variables by Markov Blanket. Finally LSBN employs an efficient algorithm, to merge structures of overlapping communities into a whole. In comparison with other four state-of-art large-scale network structure learning algorithms such as ARACNE, PC, Greedy Search and MMHC, LSBN shows comparable results in five common benchmark datasets, evaluated by precision, recall and f-score. What's more, LSBN makes it possible to learn large-scale Bayesian structure by Model Averaging which used to be intractable. In summary, LSBN provides an scalable and parallel framework for the reconstruction of network structures. Besides, the complete information of overlapping communities serves as the byproduct, which could be used to mine meaningful clusters in biological networks, such as protein-protein-interaction network or gene regulatory network, as well as in social network.
The third major approach performs a score-and-search strategy. In general, score-and-search algorithms search through structure space guided by a scoring function. One of the most basic score-and-search algorithms is Greedy Search @cite_4 . Since the size of structure space grows super-exponentially, the search approach would get inevitably trapped into local maximum, even there are many ways to escape, such as random restarts, simulated annealing or search in the space of equivalence classes of DAGs, called PDAGs.
@cite_4
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We discuss the relationships between three approaches to greedy heuristic search: best-first, hill-climbing, and beam search. We consider the design decisions within each family and point out their oft-overlooked similarities. We consider the following best-first searches: weighted A*, greedy search, ASeps, window A* and multi-state commitment k-weighted A*. For hill climbing algorithms, we consider enforced hill climbing and LSS-LRTA*. We also consider a variety of beam searches, including BULB and beam-stack search. We show how to best configure beam search in order to maximize robustness. An empirical analysis on six standard benchmarks reveals that beam search and best-first search have remarkably similar performance, and outperform hill-climbing approaches in terms of both time to solution and solution quality. Of these, beam search is preferable for very large problems and best first search is better on problems where the goal cannot be reached from all states. [See the paper for the full abstract.] We show tight upper and lower bounds for time-space trade-offs for the @math -Approximate Near Neighbor Search problem. For the @math -dimensional Euclidean space and @math -point datasets, we develop a data structure with space @math and query time @math for every @math such that: This is the first data structure that achieves sublinear query time and near-linear space for every approximation factor @math , improving upon [Kapralov, PODS 2015]. The data structure is a culmination of a long line of work on the problem for all space regimes; it builds on Spherical Locality-Sensitive Filtering [Becker, Ducas, Gama, Laarhoven, SODA 2016] and data-dependent hashing [Andoni, Indyk, Nguyen, Razenshteyn, SODA 2014] [Andoni, Razenshteyn, STOC 2015]. Our matching lower bounds are of two types: conditional and unconditional. First, we prove tightness of the whole above trade-off in a restricted model of computation, which captures all known hashing-based approaches. We then show unconditional cell-probe lower bounds for one and two probes that match the above trade-off for @math , improving upon the best known lower bounds from [Panigrahy, Talwar, Wieder, FOCS 2010]. In particular, this is the first space lower bound (for any static data structure) for two probes which is not polynomially smaller than the one-probe bound. To show the result for two probes, we establish and exploit a connection to locally-decodable codes. We study the problem of incrementally maintaining a topological sorting in a large DAG. The Discovery Algorithm (DA) of [Proc. 1st Annual ACM-SIAM Symp. on Discrete Algorithms, 1990, pp. 32-42] computes a cover K of nodes such that a solution to the modified problem can be found by changing node priorities within K only. It achieves a runtime complexity that is polynomially bounded in terms of the minimal cover size k.The temporary space complexity of DA grows quickly with increasing number of added edges and cover size. We introduce the Depth-First Discovery Algorithm (DFDA), which uses depth-first search to reduce the temporary space of DA from O(|A| × ||-K||) to O(|A| + ||K||), where |A| is the number of edges to add and ||K|| is the extended size of the cover. DFDA is simpler than DA and performs better in our empirical tests. We consider a framework for structured prediction based on search in the space of complete structured outputs. Given a structured input, an output is produced by running a time-bounded search procedure guided by a learned cost function, and then returning the least cost output uncovered during the search. This framework can be instantiated for a wide range of search spaces and search procedures, and easily incorporates arbitrary structured-prediction loss functions. In this paper, we make two main technical contributions. First, we describe a novel approach to automatically defining an effective search space over structured outputs, which is able to leverage the availability of powerful classification learning algorithms. In particular, we define the limited-discrepancy search space and relate the quality of that space to the quality of learned classifiers. We also define a sparse version of the search space to improve the effciency of our overall approach. Second, we give a generic cost function learning approach that is applicable to a wide range of search procedures. The key idea is to learn a cost function that attempts to mimic the behavior of conducting searches guided by the true loss function. Our experiments on six benchmark domains show that a small amount of search in limited discrepancy search space is often sufficient for significantly improving on state-of-the-art structured-prediction performance. We also demonstrate significant speed improvements for our approach using sparse search spaces with little or no loss in accuracy.