With pervasive applications of medical imaging in health-care, biomedical image segmentation plays a central role in quantitative analysis, clinical diagnosis, and medical intervention. Since manual annotation suffers limited reproducibility, arduous efforts, and excessive time, automatic segmentation is desired to process increasingly larger scale histopathological data. Recently, deep neural networks (DNNs), particularly fully convolutional networks (FCNs), have been widely applied to biomedical image segmentation, attaining much improved performance. At the same time, quantization of DNNs has become an active research topic, which aims to represent weights with less memory (precision) to considerably reduce memory and computation requirements of DNNs while maintaining acceptable accuracy. In this paper, we apply quantization techniques to FCNs for accurate biomedical image segmentation. Unlike existing literatures on quantization which primarily targets memory and computation complexity reduction, we apply quantization as a method to reduce overfitting in FCNs for better accuracy. Specifically, we focus on a state-of-the-art segmentation framework, suggestive annotation [26], which judiciously extracts representative annotation samples from the original training dataset, obtaining an effective small-sized balanced training dataset. We develop two new quantization processes for this framework: (1) suggestive annotation with quantization for highly representative training samples, and (2) network training with quantization for high accuracy. Extensive experiments on the MICCAI Gland dataset show that both quantization processes can improve the segmentation performance, and our proposed method exceeds the current state-of-the-art performance by up to 1 . In addition, our method has a reduction of up to 6.4x on memory usage.
We based our proposed framework on suggestive annotation @cite_0 , which achieves state-of-the-art performance on the Gland dataset. The key idea of the work is that better performance can be achieved with representative training samples instead of original training samples. As shown in Figure , the suggestive annotation framework @cite_0 has two steps: suggestive annotation and network training. The first step extracts typical samples from the original training set with multiple suggestive FCNs, and the second step trains segmentation FCNs with the extracted samples. In the first step, multiple suggestive FCNs are trained in parallel. During the inference stage, multiple suggestive FCNs produce multiple predictions for the same input from the original training set, which can be used to calculate the representativeness of the samples.
@cite_0
2963948425 2607119937 2952103128 2899943572
With pervasive applications of medical imaging in health-care, biomedical image segmentation plays a central role in quantitative analysis, clinical diagnosis, and medical intervention. Since manual annotation suffers limited reproducibility, arduous efforts, and excessive time, automatic segmentation is desired to process increasingly larger scale histopathological data. Recently, deep neural networks (DNNs), particularly fully convolutional networks (FCNs), have been widely applied to biomedical image segmentation, attaining much improved performance. At the same time, quantization of DNNs has become an active research topic, which aims to represent weights with less memory (precision) to considerably reduce memory and computation requirements of DNNs while maintaining acceptable accuracy. In this paper, we apply quantization techniques to FCNs for accurate biomedical image segmentation. Unlike existing literatures on quantization which primarily targets memory and computation complexity reduction, we apply quantization as a method to reduce overfitting in FCNs for better accuracy. Specifically, we focus on a state-of-the-art segmentation framework, suggestive annotation [26], which judiciously extracts representative annotation samples from the original training dataset, obtaining an effective small-sized balanced training dataset. We develop two new quantization processes for this framework: (1) suggestive annotation with quantization for highly representative training samples, and (2) network training with quantization for high accuracy. Extensive experiments on the MICCAI Gland dataset show that both quantization processes can improve the segmentation performance, and our proposed method exceeds the current state-of-the-art performance by up to 1 . In addition, our method has a reduction of up to 6.4x on memory usage. This paper focuses on a novel and challenging vision task, dense video captioning, which aims to automatically describe a video clip with multiple informative and diverse caption sentences. The proposed method is trained without explicit annotation of fine-grained sentence to video region-sequence correspondence, but is only based on weak video-level sentence annotations. It differs from existing video captioning systems in three technical aspects. First, we propose lexical fully convolutional neural networks (Lexical-FCN) with weakly supervised multi-instance multi-label learning to weakly link video regions with lexical labels. Second, we introduce a novel submodular maximization scheme to generate multiple informative and diverse region-sequences based on the Lexical-FCN outputs. A winner-takes-all scheme is adopted to weakly associate sentences to region-sequences in the training phase. Third, a sequence-to-sequence learning based language model is trained with the weakly supervised information obtained through the association process. We show that the proposed method can not only produce informative and diverse dense captions, but also outperform state-of-the-art single video captioning methods by a large margin. This paper focuses on a novel and challenging vision task, dense video captioning, which aims to automatically describe a video clip with multiple informative and diverse caption sentences. The proposed method is trained without explicit annotation of fine-grained sentence to video region-sequence correspondence, but is only based on weak video-level sentence annotations. It differs from existing video captioning systems in three technical aspects. First, we propose lexical fully convolutional neural networks (Lexical-FCN) with weakly supervised multi-instance multi-label learning to weakly link video regions with lexical labels. Second, we introduce a novel submodular maximization scheme to generate multiple informative and diverse region-sequences based on the Lexical-FCN outputs. A winner-takes-all scheme is adopted to weakly associate sentences to region-sequences in the training phase. Third, a sequence-to-sequence learning based language model is trained with the weakly supervised information obtained through the association process. We show that the proposed method can not only produce informative and diverse dense captions, but also outperform state-of-the-art single video captioning methods by a large margin. Annotating the right data for training deep neural networks is an important challenge. Active learning using uncertainty estimates from Bayesian Neural Networks (BNNs) could provide an effective solution to this. Despite being theoretically principled, BNNs require approximations to be applied to large-scale problems, where both performance and uncertainty estimation are crucial. In this paper, we introduce Deep Probabilistic Ensembles (DPEs), a scalable technique that uses a regularized ensemble to approximate a deep BNN. We conduct a series of large-scale visual active learning experiments to evaluate DPEs on classification with the CIFAR-10, CIFAR-100 and ImageNet datasets, and semantic segmentation with the BDD100k dataset. Our models require significantly less training data to achieve competitive performances, and steadily improve upon strong active learning baselines as the annotation budget is increased.