The MIMIC-CXR dataset is (to date) the largest released chest x-ray dataset consisting of 473,064 chest x-rays and 206,574 radiology reports collected from 63,478 patients. We present the results of training and evaluating a collection of deep convolutional neural networks on this dataset to recognize multiple common thorax diseases. To the best of our knowledge, this is the first work that trains CNNs for this task on such a large collection of chest x-ray images, which is over four times the size of the largest previously released chest x-ray corpus (ChestX-Ray14). We describe and evaluate individual CNN models trained on frontal and lateral CXR view types. In addition, we present a novel DualNet architecture that emulates routine clinical practice by simultaneously processing both frontal and lateral CXR images obtained from a radiological exam. Our DualNet architecture shows improved performance in recognizing findings in CXR images when compared to applying separate baseline frontal and lateral classifiers.
While computer-aided diagnosis in chest radiography has been studied for many years , the public release of the ChestX-ray14 dataset has resulted in many recent works that attempt to classify thorax diseases from frontal chest x-rays . Perhaps the most well-known of these works is that of @cite_0 , in which the authors present the ChexNet system. In addition to evaluating ChexNet by determining how well the model classifies 14 thorax diseases labeled within the ChestX-ray14 dataset, @cite_0 extracted a subset of 420 images and evaluated the performance of a binary ChexNet model trained to detect pneumonia. They compare the performance of ChexNet to that of four practicing academic radiologists and show that ChexNet was able to achieve a better @math score compared to the average score from the radiologists.
@cite_0
2770241596 2611650229 2770384498 2884149198
We develop an algorithm that can detect pneumonia from chest X-rays at a level exceeding practicing radiologists. Our algorithm, CheXNet, is a 121-layer convolutional neural network trained on ChestX-ray14, currently the largest publicly available chest X-ray dataset, containing over 100,000 frontal-view X-ray images with 14 diseases. Four practicing academic radiologists annotate a test set, on which we compare the performance of CheXNet to that of radiologists. We find that CheXNet exceeds average radiologist performance on the F1 metric. We extend CheXNet to detect all 14 diseases in ChestX-ray14 and achieve state of the art results on all 14 diseases. The chest X-ray is one of the most commonly accessible radiological examinations for screening and diagnosis of many lung diseases. A tremendous number of X-ray imaging studies accompanied by radiological reports are accumulated and stored in many modern hospitals Picture Archiving and Communication Systems (PACS). On the other side, it is still an open question how this type of hospital-size knowledge database containing invaluable imaging informatics (i.e., loosely labeled) can be used to facilitate the data-hungry deep learning paradigms in building truly large-scale high precision computer-aided diagnosis (CAD) systems. In this paper, we present a new chest X-ray database, namely ChestX-ray8, which comprises 108,948 frontal-view X-ray images of 32,717 unique patients with the text-mined eight disease image labels (where each image can have multi-labels), from the associated radiological reports using natural language processing. Importantly, we demonstrate that these commonly occurring thoracic diseases can be detected and even spatially-located via a unified weakly-supervised multi-label image classification and disease localization framework, which is validated using our proposed dataset. Although the initial quantitative results are promising as reported, deep convolutional neural network based reading chest X-rays (i.e., recognizing and locating the common disease patterns trained with only image-level labels) remains a strenuous task for fully-automated high precision CAD systems. Chest X-ray is one of the most accessible medical imaging technique for diagnosis of multiple diseases. With the availability of ChestX-ray14, which is a massive dataset of chest X-ray images and provides annotations for 14 thoracic diseases; it is possible to train Deep Convolutional Neural Networks (DCNN) to build Computer Aided Diagnosis (CAD) systems. In this work, we experiment a set of deep learning models and present a cascaded deep neural network that can diagnose all 14 pathologies better than the baseline and is competitive with other published methods. Our work provides the quantitative results to answer following research questions for the dataset: 1) What loss functions to use for training DCNN from scratch on ChestX-ray14 dataset that demonstrates high class imbalance and label co occurrence? 2) How to use cascading to model label dependency and to improve accuracy of the deep learning model? Chest X-rays is one of the most commonly available and affordable radiological examinations in clinical practice. While detecting thoracic diseases on chest X-rays is still a challenging task for machine intelligence, due to 1) the highly varied appearance of lesion areas on X-rays from patients of different thoracic disease and 2) the shortage of accurate pixel-level annotations by radiologists for model training. Existing machine learning methods are unable to deal with the challenge that thoracic diseases usually happen in localized disease-specific areas. In this article, we propose a weakly supervised deep learning framework equipped with squeeze-and-excitation blocks, multi-map transfer and max-min pooling for classifying common thoracic diseases as well as localizing suspicious lesion regions on chest X-rays. The comprehensive experiments and discussions are performed on the ChestX-ray14 dataset. Both numerical and visual results have demonstrated the effectiveness of proposed model and its better performance against the state-of-the-art pipelines.