Digital whole-slide images of pathological tissue samples have recently become feasible for use within routine diagnostic practice. These gigapixel sized images enable pathologists to perform reviews using computer workstations instead of microscopes. Existing workstations visualize scanned images by providing a zoomable image space that reproduces the capabilities of the microscope. This paper presents a novel visualization approach that enables filtering of the scale-space according to color preference. The visualization method reveals diagnostically important patterns that are otherwise not visible. The paper demonstrates how this approach has been implemented into a fully functional prototype that lets the user navigate the visualization parameter space in real time. The prototype was evaluated for two common clinical tasks with eight pathologists in a within-subjects study. The data reveal that task efficiency increased by 15 using the prototype, with maintained accuracy. By analyzing behavioral strategies, it was possible to conclude that efficiency gain was caused by a reduction of the panning needed to perform systematic search of the images. The prototype system was well received by the pathologists who did not detect any risks that would hinder use in clinical routine.
Another way to raise the salience of important visual features is to modify their apparent size. @cite_12 enlarged image regions based on a user-selected transfer function. Correa and Ma @cite_14 @cite_15 experimented with local size and occlusion of objects as an additional parameter to the transfer function to increase different discrimination possibilities between image features. Our method also extracts important details from a large dataset, but brings this capability to the domain of large two-dimensional images.
@cite_15 @cite_14 @cite_12
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In this paper we propose a novel computational method to infer visual saliency in images. The method is based on the idea that salient objects should have local characteristics that are different than the rest of the scene, being edges, color or shape. By using a novel operator, these characteristics are combined to infer global information. The obtained information is used as a weighting for the output of a segmentation algorithm so that the salient object in the scene can easily be distinguished from the background. The proposed approach is fast and it does not require any learning. The experimentation shows that the system can enhance interesting objects in images and it is able to correctly locate the same object annotated by humans with an F-measure of 85.61 when the object size is known, and 79.19 when the object size is unknown, improving the state of the art performance on a public dataset. If a physical object has a smooth or piecewise smooth boundary, its images obtained by cameras in varying positions undergo smooth apparent deformations. These deformations are locally well approximated by affine transforms of the image plane. In consequence the solid object recognition problem has often been led back to the computation of affine invariant image local features. Such invariant features could be obtained by normalization methods, but no fully affine normalization method exists for the time being. Even scale invariance is dealt with rigorously only by the scale-invariant feature transform (SIFT) method. By simulating zooms out and normalizing translation and rotation, SIFT is invariant to four out of the six parameters of an affine transform. The method proposed in this paper, affine-SIFT (ASIFT), simulates all image views obtainable by varying the two camera axis orientation parameters, namely, the latitude and the longitude angles, left over by the SIFT method. Then it covers the other four parameters by using the SIFT method itself. The resulting method will be mathematically proved to be fully affine invariant. Against any prognosis, simulating all views depending on the two camera orientation parameters is feasible with no dramatic computational load. A two-resolution scheme further reduces the ASIFT complexity to about twice that of SIFT. A new notion, the transition tilt, measuring the amount of distortion from one view to another, is introduced. While an absolute tilt from a frontal to a slanted view exceeding 6 is rare, much higher transition tilts are common when two slanted views of an object are compared (see Figure hightransitiontiltsillustration). The attainable transition tilt is measured for each affine image comparison method. The new method permits one to reliably identify features that have undergone transition tilts of large magnitude, up to 36 and higher. This fact is substantiated by many experiments which show that ASIFT significantly outperforms the state-of-the-art methods SIFT, maximally stable extremal region (MSER), Harris-affine, and Hessian-affine. The visualization of complex 3D images remains a challenge, a fact that is magnified by the difficulty to classify or segment volume data. In this paper, we introduce size-based transfer functions, which map the local scale of features to color and opacity. Features in a data set with similar or identical scalar values can be classified based on their relative size. We achieve this with the use of scale fields, which are 3D fields that represent the relative size of the local feature at each voxel. We present a mechanism for obtaining these scale fields at interactive rates, through a continuous scale-space analysis and a set of detection filters. Through a number of examples, we show that size-based transfer functions can improve classification and enhance volume rendering techniques, such as maximum intensity projection. The ability to classify objects based on local size at interactive rates proves to be a powerful method for complex data exploration. The objective of this paper is large scale object instance retrieval, given a query image. A starting point of such systems is feature detection and description, for example using SIFT. The focus of this paper, however, is towards very large scale retrieval where, due to storage requirements, very compact image descriptors are required and no information about the original SIFT descriptors can be accessed directly at run time. We start from VLAD, the state-of-the art compact descriptor introduced by for this purpose, and make three novel contributions: first, we show that a simple change to the normalization method significantly improves retrieval performance, second, we show that vocabulary adaptation can substantially alleviate problems caused when images are added to the dataset after initial vocabulary learning. These two methods set a new state-of-the-art over all benchmarks investigated here for both mid-dimensional (20k-D to 30k-D) and small (128-D) descriptors. Our third contribution is a multiple spatial VLAD representation, MultiVLAD, that allows the retrieval and localization of objects that only extend over a small part of an image (again without requiring use of the original image SIFT descriptors).