With pervasive applications of medical imaging in health-care, biomedical image segmentation plays a central role in quantitative analysis, clinical diagnosis, and medical intervention. Since manual annotation suffers limited reproducibility, arduous efforts, and excessive time, automatic segmentation is desired to process increasingly larger scale histopathological data. Recently, deep neural networks (DNNs), particularly fully convolutional networks (FCNs), have been widely applied to biomedical image segmentation, attaining much improved performance. At the same time, quantization of DNNs has become an active research topic, which aims to represent weights with less memory (precision) to considerably reduce memory and computation requirements of DNNs while maintaining acceptable accuracy. In this paper, we apply quantization techniques to FCNs for accurate biomedical image segmentation. Unlike existing literatures on quantization which primarily targets memory and computation complexity reduction, we apply quantization as a method to reduce overfitting in FCNs for better accuracy. Specifically, we focus on a state-of-the-art segmentation framework, suggestive annotation [26], which judiciously extracts representative annotation samples from the original training dataset, obtaining an effective small-sized balanced training dataset. We develop two new quantization processes for this framework: (1) suggestive annotation with quantization for highly representative training samples, and (2) network training with quantization for high accuracy. Extensive experiments on the MICCAI Gland dataset show that both quantization processes can improve the segmentation performance, and our proposed method exceeds the current state-of-the-art performance by up to 1 . In addition, our method has a reduction of up to 6.4x on memory usage.
Note that each FCN generates two outputs: contour of the objects and the segmented object. The suggestive FCNs and segmentation FCNs have the same network structure which is based on DCAN @cite_11 and active learning.
@cite_11
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Fully convolutional networks (FCNs) have been proven very successful for semantic segmentation, but the FCN outputs are unaware of object instances. In this paper, we develop FCNs that are capable of proposing instance-level segment candidates. In contrast to the previous FCN that generates one score map, our FCN is designed to compute a small set of instance-sensitive score maps, each of which is the outcome of a pixel-wise classifier of a relative position to instances. On top of these instance-sensitive score maps, a simple assembling module is able to output instance candidate at each position. In contrast to the recent DeepMask method for segmenting instances, our method does not have any high-dimensional layer related to the mask resolution, but instead exploits image local coherence for estimating instances. We present competitive results of instance segment proposal on both PASCAL VOC and MS COCO. Fully convolutional networks (FCNs) have been proven very successful for semantic segmentation, but the FCN outputs are unaware of object instances. In this paper, we develop FCNs that are capable of proposing instance-level segment candidates. In contrast to the previous FCN that generates one score map, our FCN is designed to compute a small set of instance-sensitive score maps, each of which is the outcome of a pixel-wise classifier of a relative position to instances. On top of these instance-sensitive score maps, a simple assembling module is able to output instance candidate at each position. In contrast to the recent DeepMask method for segmenting instances, our method does not have any high-dimensional layer related to the mask resolution, but instead exploits image local coherence for estimating instances. We present competitive results of instance segment proposal on both PASCAL VOC and MS COCO. With the development of Fully Convolutional Neural Network (FCN), there have been progressive advances in the field of semantic segmentation in recent years. The FCN-based solutions are able to summarize features across training images and generate matching templates for the desired object classes, yet they overlook intra-class difference (ICD) among multiple instances in the same class. In this work, we present a novel fine-to-coarse learning (FCL) procedure, which first guides the network with designed 'finer' sub-class labels, whose decisions are mapped to the original 'coarse' object category through end-to-end learning. A sub-class labeling strategy is designed with unsupervised clustering upon deep convolutional features, and the proposed FCL procedure enables a balance between the fine-scale (i.e. sub-class) and the coarse-scale (i.e. class) knowledge. We conduct extensive experiments on several popular datasets, including PASCAL VOC, Context, Person-Part and NYUDepth-v2 to demonstrate the advantage of learning finer sub-classes and the potential to guide the learning of deep networks with unsupervised clustering. Fully convolutional network (FCN) has been successfully applied in semantic segmentation of scenes represented with RGB images. Images augmented with depth channel provide more understanding of the geometric information of the scene in the image. The question is how to best exploit this additional information to improve the segmentation performance.,,In this paper, we present a neural network with multiple branches for segmenting RGB-D images. Our approach is to use the available depth to split the image into layers with common visual characteristic of objects scenes, or common “scene-resolution”. We introduce context-aware receptive field (CaRF) which provides a better control on the relevant contextual information of the learned features. Equipped with CaRF, each branch of the network semantically segments relevant similar scene-resolution, leading to a more focused domain which is easier to learn. Furthermore, our network is cascaded with features from one branch augmenting the features of adjacent branch. We show that such cascading of features enriches the contextual information of each branch and enhances the overall performance. The accuracy that our network achieves outperforms the stateof-the-art methods on two public datasets.