Multimodal registration is a challenging problem in medical imaging due the high variability of tissue appearance under different imaging modalities. The crucial component here is the choice of the right similarity measure. We make a step towards a general learning-based solution that can be adapted to specific situations and present a metric based on a convolutional neural network. Our network can be trained from scratch even from a few aligned image pairs. The metric is validated on intersubject deformable registration on a dataset different from the one used for training, demonstrating good generalization. In this task, we outperform mutual information by a significant margin.
The idea of using supervised learning to build a similarity metric for multimodal images has been explored in a number of works. On one side, there are probabilistic approaches which rely on modelling the joint-image distribution. For instance, Guetter al propose a generative method based on Kullback-Leibler Divergence @cite_3 . Our work is closer to the discriminative concept proposed by Lee al @cite_8 and Michel al @cite_6 , where the problem of learning a similarity metric is posed as binary classification. Here the goal is to discriminate between aligned and misaligned patches given pairs of aligned images. Lee al propose the use of a Structured Support Vector Machine while Michel al use a method based on Adaboost. Different to these approaches we rely on CNN as our learning method of choice as the suitable set of characteristics for each type of modality combinations can be directly learned from the training data.
@cite_6 @cite_3 @cite_8
2142863987 2334328509 2949257576 2762941833
Metric learning aims at finding a distance that approximates a task-specific notion of semantic similarity. Typically, a Mahalanobis distance is learned from pairs of data labeled as being semantically similar or not. In this paper, we learn such metrics in a weakly supervised setting where "bags" of instances are labeled with "bags" of labels. We formulate the problem as a multiple instance learning (MIL) problem over pairs of bags. If two bags share at least one label, we label the pair positive, and negative otherwise. We propose to learn a metric using those labeled pairs of bags, leading to MildML, for multiple instance logistic discriminant metric learning. MildML iterates between updates of the metric and selection of putative positive pairs of examples from positive pairs of bags. To evaluate our approach, we introduce a large and challenging data set, Labeled Yahoo! News, which we have manually annotated and contains 31147 detected faces of 5873 different people in 20071 images. We group the faces detected in an image into a bag, and group the names detected in the caption into a corresponding set of labels. When the labels come from manual annotation, we find that MildML using the bag-level annotation performs as well as fully supervised metric learning using instance-level annotation. We also consider performance in the case of automatically extracted labels for the bags, where some of the bag labels do not correspond to any example in the bag. In this case MildML works substantially better than relying on noisy instance-level annotations derived from the bag-level annotation by resolving face-name associations in images with their captions. The present embodiments relate to machine learning for multimodal image data. By way of introduction, the present embodiments described below include apparatuses and methods for learning a similarity metric using deep learning based techniques for multimodal medical images. A novel similarity metric for multi-modal images is provided using the corresponding states of pairs of image patches to generate a classification setting for each pair. The classification settings are used to train a deep neural network via supervised learning. A multi-modal stacked denoising auto encoder (SDAE) is used to pre-train the neural network. A continuous and smooth similarity metric is constructed based on the output of the neural network before activation in the last layer. The trained similarity metric may be used to improve the results of image fusion. The main contribution of this paper is a simple semi-supervised pipeline that only uses the original training set without collecting extra data. It is challenging in 1) how to obtain more training data only from the training set and 2) how to use the newly generated data. In this work, the generative adversarial network (GAN) is used to generate unlabeled samples. We propose the label smoothing regularization for outliers (LSRO). This method assigns a uniform label distribution to the unlabeled images, which regularizes the supervised model and improves the baseline. We verify the proposed method on a practical problem: person re-identification (re-ID). This task aims to retrieve a query person from other cameras. We adopt the deep convolutional generative adversarial network (DCGAN) for sample generation, and a baseline convolutional neural network (CNN) for representation learning. Experiments show that adding the GAN-generated data effectively improves the discriminative ability of learned CNN embeddings. On three large-scale datasets, Market-1501, CUHK03 and DukeMTMC-reID, we obtain +4.37 , +1.6 and +2.46 improvement in rank-1 precision over the baseline CNN, respectively. We additionally apply the proposed method to fine-grained bird recognition and achieve a +0.6 improvement over a strong baseline. The code is available at this https URL With the development of deep learning, supervised learning has frequently been adopted to classify remotely sensed images using convolutional networks. However, due to the limited amount of labeled data available, supervised learning is often difficult to carry out. Therefore, we proposed an unsupervised model called multiple-layer feature-matching generative adversarial networks (MARTA GANs) to learn a representation using only unlabeled data. MARTA GANs consists of both a generative model @math and a discriminative model @math . We treat @math as a feature extractor. To fit the complex properties of remote sensing data, we use a fusion layer to merge the mid-level and global features. @math can produce numerous images that are similar to the training data; therefore, @math can learn better representations of remotely sensed images using the training data provided by @math . The classification results on two widely used remote sensing image databases show that the proposed method significantly improves the classification performance compared with other state-of-the-art methods.