Objective: Herein, a neural network-based liver segmentation algorithm is proposed, and its performance was evaluated using abdominal computed tomography (CT) images. Methods: A fully convolutional network was developed to overcome the volumetric image segmentation problem. To guide a neural network to accurately delineate a target liver object, the network was deeply supervised by applying the adaptive self-supervision scheme to derive the essential contour, which acted as a complement with the global shape. The discriminative contour, shape, and deep features were internally merged for the segmentation results. Results and Conclusion: 160 abdominal CT images were used for training and validation. The quantitative evaluation of the proposed network was performed through an eight-fold cross-validation. The result showed that the method, which uses the contour feature, segmented the liver more accurately than the state-of-the-art with a 2.13 improvement in the dice score. Significance: In this study, a new framework was introduced to guide a neural network and learn complementary contour features. The proposed neural network demonstrates that the guided contour features can significantly improve the performance of the segmentation task.
The V-net is a volumetric FCN used for medical image segmentation @cite_55 . The U-net architecture @cite_45 was extended to a volumetric convolution (i.e., 3D convolution), and U-net-like downward and upward transitions (i.e., convolutional reduction and de-convolutional expanding of feature dimensions @cite_55 ) were adopted together with multiple skip connections via an element-wise summation scheme. The dice loss was first presented to overcome the class imbalance issue.
@cite_55 @cite_45
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U-Net has been providing state-of-the-art performance in many medical image segmentation problems. Many modifications have been proposed for U-Net, such as attention U-Net, recurrent residual convolutional U-Net (R2-UNet), and U-Net with residual blocks or blocks with dense connections. However, all these modifications have an encoder-decoder structure with skip connections, and the number of paths for information flow is limited. We propose LadderNet in this paper, which can be viewed as a chain of multiple U-Nets. Instead of only one pair of encoder branch and decoder branch in U-Net, a LadderNet has multiple pairs of encoder-decoder branches, and has skip connections between every pair of adjacent decoder and decoder branches in each level. Inspired by the success of ResNet and R2-UNet, we use modified residual blocks where two convolutional layers in one block share the same weights. A LadderNet has more paths for information flow because of skip connections and residual blocks, and can be viewed as an ensemble of Fully Convolutional Networks (FCN). The equivalence to an ensemble of FCNs improves segmentation accuracy, while the shared weights within each residual block reduce parameter number. Semantic segmentation is essential for retinal disease detection. We tested LadderNet on two benchmark datasets for blood vessel segmentation in retinal images, and achieved superior performance over methods in the literature. The implementation is provided https: github.com juntang-zhuang LadderNet Convolutional neural networks (CNNs) have revolutionized medical image analysis over the past few years. The U-Net architecture is one of the most well-known CNN architectures for semantic segmentation and has achieved remarkable successes in many different medical image segmentation applications. The U-Net architecture consists of standard convolution layers, pooling layers, and upsampling layers. These convolution layers learn representative features of input images and construct segmentations based on the features. However, the features learned by standard convolution layers are not distinctive when the differences among different categories are subtle in terms of intensity, location, shape, and size. In this paper, we propose a novel CNN architecture, called Dense-Res-Inception Net (DRINet), which addresses this challenging problem. The proposed DRINet consists of three blocks, namely a convolutional block with dense connections, a deconvolutional block with residual inception modules, and an unpooling block. Our proposed architecture outperforms the U-Net in three different challenging applications, namely multi-class segmentation of cerebrospinal fluid on brain CT images, multi-organ segmentation on abdominal CT images, and multi-class brain tumor segmentation on MR images. Recent advances in deep learning, like 3D fully convolutional networks (FCNs), have improved the state-of-the-art in dense semantic segmentation of medical images. However, most network architectures require severely downsampling or cropping the images to meet the memory limitations of today's GPU cards while still considering enough context in the images for accurate segmentation. In this work, we propose a novel approach that utilizes auto-context to perform semantic segmentation at higher resolutions in a multi-scale pyramid of stacked 3D FCNs. We train and validate our models on a dataset of manually annotated abdominal organs and vessels from 377 clinical CT images used in gastric surgery, and achieve promising results with close to 90 Dice score on average. For additional evaluation, we perform separate testing on datasets from different sources and achieve competitive results, illustrating the robustness of the model and approach. With the development of Fully Convolutional Neural Network (FCN), there have been progressive advances in the field of semantic segmentation in recent years. The FCN-based solutions are able to summarize features across training images and generate matching templates for the desired object classes, yet they overlook intra-class difference (ICD) among multiple instances in the same class. In this work, we present a novel fine-to-coarse learning (FCL) procedure, which first guides the network with designed 'finer' sub-class labels, whose decisions are mapped to the original 'coarse' object category through end-to-end learning. A sub-class labeling strategy is designed with unsupervised clustering upon deep convolutional features, and the proposed FCL procedure enables a balance between the fine-scale (i.e. sub-class) and the coarse-scale (i.e. class) knowledge. We conduct extensive experiments on several popular datasets, including PASCAL VOC, Context, Person-Part and NYUDepth-v2 to demonstrate the advantage of learning finer sub-classes and the potential to guide the learning of deep networks with unsupervised clustering.