Image alignment across domains has recently become one of the realistic and popular topics in the research community. In this problem, a deep learning-based image alignment method is usually trained on an available largescale database. During the testing steps, this trained model is deployed on unseen images collected under different camera conditions and modalities. The delivered deep network models are unable to be updated, adapted or fine-tuned in these scenarios. Thus, recent deep learning techniques, e.g. domain adaptation, feature transferring, and fine-tuning, are unable to be deployed. This paper presents a novel deep learning based approach to tackle the problem of across unseen modalities. The proposed network is then applied to image alignment as an illustration. The proposed approach is designed as an end-to-end deep convolutional neural network to optimize the deep models to improve the performance. The proposed network has been evaluated in digit recognition when the model is trained on MNIST and then tested on unseen domain MNIST-M. Finally, the proposed method is benchmarked in image alignment problem when training on RGB images and testing on Depth and X-Ray images.
Image alignment for medical images has been early developed. They are feature-based methods, e.g. SIFT @cite_17 , SURF @cite_15 , popularly adopted for general computer vision applications, especially in image alignment. Xiahai et. al. @cite_6 presented a conception-normal vector information to evaluate the similarity between two images. Jingfan et. al. @cite_9 introduced an unsupervised image alignment for medical images. The registration network is trained based on feedbacks from the discrimination network designed to judge whether a pair of registered images is aligned.
@cite_9 @cite_15 @cite_6 @cite_17
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While image alignment has been studied in different areas of computer vision for decades, aligning images depicting different scenes remains a challenging problem. Analogous to optical flow, where an image is aligned to its temporally adjacent frame, we propose SIFT flow, a method to align an image to its nearest neighbors in a large image corpus containing a variety of scenes. The SIFT flow algorithm consists of matching densely sampled, pixelwise SIFT features between two images while preserving spatial discontinuities. The SIFT features allow robust matching across different scene object appearances, whereas the discontinuity-preserving spatial model allows matching of objects located at different parts of the scene. Experiments show that the proposed approach robustly aligns complex scene pairs containing significant spatial differences. Based on SIFT flow, we propose an alignment-based large database framework for image analysis and synthesis, where image information is transferred from the nearest neighbors to a query image according to the dense scene correspondence. This framework is demonstrated through concrete applications such as motion field prediction from a single image, motion synthesis via object transfer, satellite image registration, and face recognition. A new approach to the problem of multimodality medical image registration is proposed, using a basic concept from information theory, mutual information (MI), or relative entropy, as a new matching criterion. The method presented in this paper applies MI to measure the statistical dependence or information redundancy between the image intensities of corresponding voxels in both images, which is assumed to be maximal if the images are geometrically aligned. Maximization of MI is a very general and powerful criterion, because no assumptions are made regarding the nature of this dependence and no limiting constraints are imposed on the image content of the modalities involved. The accuracy of the MI criterion is validated for rigid body registration of computed tomography (CT), magnetic resonance (MR), and photon emission tomography (PET) images by comparison with the stereotactic registration solution, while robustness is evaluated with respect to implementation issues, such as interpolation and optimization, and image content, including partial overlap and image degradation. Our results demonstrate that subvoxel accuracy with respect to the stereotactic reference solution can be achieved completely automatically and without any prior segmentation, feature extraction, or other preprocessing steps which makes this method very well suited for clinical applications. Image registration, the process of aligning two or more images, is the core technique of many (semi-)automatic medical image analysis tasks. Recent studies have shown that deep learning methods, notably convolutional neural networks (ConvNets), can be used for image registration. Thus far training of ConvNets for registration was supervised using predefined example registrations. However, obtaining example registrations is not trivial. To circumvent the need for predefined examples, and thereby to increase convenience of training ConvNets for image registration, we propose the Deep Learning Image Registration (DLIR) framework for unsupervised affine and deformable image registration. In the DLIR framework ConvNets are trained for image registration by exploiting image similarity analogous to conventional intensity-based image registration. After a ConvNet has been trained with the DLIR framework, it can be used to register pairs of unseen images in one shot. We propose flexible ConvNets designs for affine image registration and for deformable image registration. By stacking multiple of these ConvNets into a larger architecture, we are able to perform coarse-to-fine image registration. We show for registration of cardiac cine MRI and registration of chest CT that performance of the DLIR framework is comparable to conventional image registration while being several orders of magnitude faster. Unsupervised joint alignment of images has been demonstrated to improve performance on recognition tasks such as face verification. Such alignment reduces undesired variability due to factors such as pose, while only requiring weak supervision in the form of poorly aligned examples. However, prior work on unsupervised alignment of complex, real-world images has required the careful selection of feature representation based on hand-crafted image descriptors, in order to achieve an appropriate, smooth optimization landscape. In this paper, we instead propose a novel combination of unsupervised joint alignment with unsupervised feature learning. Specifically, we incorporate deep learning into the congealing alignment framework. Through deep learning, we obtain features that can represent the image at differing resolutions based on network depth, and that are tuned to the statistics of the specific data being aligned. In addition, we modify the learning algorithm for the restricted Boltzmann machine by incorporating a group sparsity penalty, leading to a topographic organization of the learned filters and improving subsequent alignment results. We apply our method to the Labeled Faces in the Wild database (LFW). Using the aligned images produced by our proposed unsupervised algorithm, we achieve higher accuracy in face verification compared to prior work in both unsupervised and supervised alignment. We also match the accuracy for the best available commercial method.