Parameter inference for stochastic differential equations is challenging due to the presence of a latent diffusion process. Working with an Euler-Maruyama discretisation for the diffusion, we use variational inference to jointly learn the parameters and the diffusion paths. We use a standard mean-field variational approximation of the parameter posterior, and introduce a recurrent neural network to approximate the posterior for the diffusion paths conditional on the parameters. This neural network learns how to provide Gaussian state transitions which bridge between observations in a very similar way to the conditioned diffusion process. The resulting black-box inference method can be applied to any SDE system with light tuning requirements. We illustrate the method on a Lotka-Volterra system and an epidemic model, producing accurate parameter estimates in a few hours.
Several authors have looked at variational inference for SDEs @cite_19 or related problems such as Markov jump processes @cite_12 and state space models @cite_23 @cite_14 . The novelty of our approach is to use: (1) stochastic optimisation rather than variational calculus; (2) a RNN-based variational approximation for the latent states instead of a mean-field or multivariate Gaussian approach. We expect (2) is especially relevant to sparsely observed SDEs, where the latent states between observations may have a particularly complex dependency structure.
@cite_19 @cite_14 @cite_23 @cite_12
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We present a novel approach to inference in conditionally Gaussian continuous time stochastic processes, where the latent process is a Markovian jump process. We first consider the case of jump-diffusion processes, where the drift of a linear stochastic differential equation can jump at arbitrary time points. We derive partial differential equations for exact inference and present a very efficient mean field approximation. By introducing a novel lower bound on the free energy, we then generalise our approach to Gaussian processes with arbitrary covariance, such as the non-Markovian RBF covariance. We present results on both simulated and real data, showing that the approach is very accurate in capturing latent dynamics and can be useful in a number of real data modelling tasks. Models defined by stochastic differential equations (SDEs) allow for the representation of random variability in dynamical systems. The relevance of this class of models is growing in many applied research areas and is already a standard tool to model, for example, financial, neuronal, and population growth dynamics. However, inference for multidimensional SDE models is still very challenging, both computationally and theoretically. Approximate Bayesian computation (ABC) allows to perform Bayesian inference for models which are sufficiently complex that the likelihood function is either analytically unavailable or computationally prohibitive to evaluate. A computationally efficient ABC-MCMC algorithm is proposed, halving the running time in our simulations. Focus here is on the case where the SDE describes latent dynamics in state-space models; however, the methodology is not limited to the state-space framework. We consider simulation studies for a pharmacokinetics pharmacodynamics model and for stochast... Stochastic variational inference makes it possible to approximate posterior distributions induced by large datasets quickly using stochastic optimization. The algorithm relies on the use of fully factorized variational distributions. However, this "mean-field" independence approximation limits the fidelity of the posterior approximation, and introduces local optima. We show how to relax the mean-field approximation to allow arbitrary dependencies between global parameters and local hidden variables, producing better parameter estimates by reducing bias, sensitivity to local optima, and sensitivity to hyperparameters. Until recently, the lack of ground truth data has hindered the application of discriminative structured prediction techniques to the stereo problem. In this paper we use ground truth data sets that we have recently constructed to explore different model structures and parameter learning techniques. To estimate parameters in Markov random fields (MRFs) via maximum likelihood one usually needs to perform approximate probabilistic inference. Conditional random fields (CRFs) are discriminative versions of traditional MRFs. We explore a number of novel CRF model structures including a CRF for stereo matching with an explicit occlusion model. CRFs require expensive inference steps for each iteration of optimization and inference is particularly slow when there are many discrete states. We explore belief propagation, variational message passing and graph cuts as inference methods during learning and compare with learning via pseudolikelihood. To accelerate approximate inference we have developed a new method called sparse variational message passing which can reduce inference time by an order of magnitude with negligible loss in quality. Learning using sparse variational message passing improves upon previous approaches using graph cuts and allows efficient learning over large data sets when energy functions violate the constraints imposed by graph cuts.