Ability to quantify and predict progression of a disease is fundamental for selecting an appropriate treatment. Many clinical metrics cannot be acquired frequently either because of their cost (e.g. MRI, gait analysis) or because they are inconvenient or harmful to a patient (e.g. biopsy, x-ray). In such scenarios, in order to estimate individual trajectories of disease progression, it is advantageous to leverage similarities between patients, i.e. the covariance of trajectories, and find a latent representation of progression. Most of existing methods for estimating trajectories do not account for events in-between observations, what dramatically decreases their adequacy for clinical practice. In this study, we develop a machine learning framework named Coordinatewise-Soft-Impute (CSI) for analyzing disease progression from sparse observations in the presence of confounding events. CSI is guaranteed to converge to the global minimum of the corresponding optimization problem. Experimental results also demonstrates the effectiveness of CSI using both simulated and real dataset.
In linear mixed-effect model, each trajectory is estimated with @math degrees of freedom, which can still be too complex when observations are sparse. One typical solution is to assume a low-rank structure of the covariance matrix @math by introducing a contraction mapping @math from the functional basis to a low-dimensional latent space. More specifically, one may rewrite the LMM model as where @math is a @math matrix with @math and @math is the new, shorter random effect to be estimated. Methods based on low-rank approximations are widely adopted and applied in practice and different algorithms on fitting the model have been proposed @cite_2 @cite_5 @cite_6 . In the later sections, we will compare our algorithm with one specific implementation named functional-Principle-Component-Analysis (fPCA) @cite_2 , which uses EM algorithm for estimating model parameters and latent variables @math .
@cite_5 @cite_6 @cite_2
1977580401 2542071751 236111108 2024051019
Recovering low-rank and sparse matrices from incomplete or corrupted observations is an important problem in statistics, machine learning, computer vision, as well as signal and image processing. In theory, this problem can be solved by the natural convex joint mixed relaxations (i.e., l 1 -norm and trace norm) under certain conditions. However, all current provable algorithms suffer from superlinear per-iteration cost, which severely limits their applicability to large-scale problems. In this paper, we propose a scalable, provable and structured robust bilinear factorization (RBF) method to recover low-rank and sparse matrices from missing and grossly corrupted data, i.e., robust matrix completion (RMC), or incomplete and grossly corrupted measurements, i.e., compressive principal component pursuit (CPCP). Specifically, we first present two small-scale matrix trace norm regularized bilinear factorization models for RMC and CPCP problems, in which repetitively calculating SVD of a large-scale matrix is replaced by updating two much smaller factor matrices. Then, we apply the alternating direction method of multipliers (ADMM) to efficiently solve the RMC problems. Finally, we provide the convergence analysis of our algorithm, and extend it to address general CPCP problems. Experimental results verified both the efficiency and effectiveness of our method compared with the state-of-the-art methods. Motivated by online recommendation and advertising systems, we consider a causal model for stochastic contextual bandits with a latent low-dimensional confounder. In our model, there are @math observed contexts and @math arms of the bandit. The observed context influences the reward obtained through a latent confounder variable with cardinality @math ( @math ). The arm choice and the latent confounder causally determines the reward while the observed context is correlated with the confounder. Under this model, the @math mean reward matrix @math (for each context in @math and each arm in @math ) factorizes into non-negative factors @math ( @math ) and @math ( @math ). This insight enables us to propose an @math -greedy NMF-Bandit algorithm that designs a sequence of interventions (selecting specific arms), that achieves a balance between learning this low-dimensional structure and selecting the best arm to minimize regret. Our algorithm achieves a regret of @math at time @math , as compared to @math for conventional contextual bandits, assuming a constant gap between the best arm and the rest for each context. These guarantees are obtained under mild sufficiency conditions on the factors that are weaker versions of the well-known Statistical RIP condition. We further propose a class of generative models that satisfy our sufficient conditions, and derive a lower bound of @math . These are the first regret guarantees for online matrix completion with bandit feedback, when the rank is greater than one. We further compare the performance of our algorithm with the state of the art, on synthetic and real world data-sets. We present a novel probabilistic approach for fitting a statistical model to an image. A 3D Morphable Model (3DMM) of faces is interpreted as a generative (Top-Down) Bayesian model. Random Forests are used as noisy detectors (Bottom-Up) for the face and facial landmark positions. The Top-Down and Bottom-Up parts are then combined using a Data-Driven Markov Chain Monte Carlo Method (DDMCMC). As core of the integration, we use the Metropolis-Hastings algorithm which has two main advantages. First, the algorithm can handle unreliable detections and therefore does not need the detectors to take an early and possible wrong hard decision before fitting. Second, it is open for integration of various cues to guide the fitting process. Based on the proposed approach, we implemented a completely automatic, pose and illumination invariant face recognition application. We are able to train and test the building blocks of our application on different databases. The system is evaluated on the Multi-PIE database and reaches state of the art performance. In this paper, we propose a rank minimization method to fuse the predicted confidence scores of multiple models, each of which is obtained based on a certain kind of feature. Specifically, we convert each confidence score vector obtained from one model into a pairwise relationship matrix, in which each entry characterizes the comparative relationship of scores of two test samples. Our hypothesis is that the relative score relations are consistent among component models up to certain sparse deviations, despite the large variations that may exist in the absolute values of the raw scores. Then we formulate the score fusion problem as seeking a shared rank-2 pairwise relationship matrix based on which each original score matrix from individual model can be decomposed into the common rank-2 matrix and sparse deviation errors. A robust score vector is then extracted to fit the recovered low rank score relation matrix. We formulate the problem as a nuclear norm and l 1 norm optimization objective function and employ the Augmented Lagrange Multiplier (ALM) method for the optimization. Our method is isotonic (i.e., scale invariant) to the numeric scales of the scores originated from different models. We experimentally show that the proposed method achieves significant performance gains on various tasks including object categorization and video event detection.