Due to low tissue contrast, irregular object appearance, and unpredictable location variation, segmenting the objects from different medical imaging modalities (e.g., CT, MR) is considered as an important yet challenging task. In this paper, we present a novel method for interactive medical image segmentation with the following merits. (1) Our design is fundamentally different from previous pure patch-based and image-based segmentation methods. We observe that during delineation, the physician repeatedly check the inside-outside intensity changing to determine the boundary, which indicates that comparison in an inside-outside manner is extremely important. Thus, we innovatively model our segmentation task as learning the representation of the bi-directional sequential patches, starting from (or ending in) the given central point of the object. This can be realized by our proposed ConvRNN network embedded with a gated memory propagation unit. (2) Unlike previous interactive methods (requiring bounding box or seed points), we only ask the physician to merely click on the rough central point of the object before segmentation, which could simultaneously enhance the performance and reduce the segmentation time. (3) We utilize our method in a multi-level framework for better performance. We systematically evaluate our method in three different segmentation tasks including CT kidney tumor, MR prostate, and PROMISE12 challenge, showing promising results compared with state-of-the-art methods. The code is available here: this https URL Sequential-patch-based-segmentation .
Moreover, from the perspective of interactive segmentation, our method belongs to the point-based interaction. Point-based interactive segmentation models have aroused increasing interest very recently. However, how to effectively integrate it with the state-of-the-art deep learning methods is still in its early stage. In @cite_14 , the points given by human were regarded as weak supervision label for segmentation. Sun @cite_13 focused on generating prior map according to the given point to improve segmentation performance. Furthermore, the RNN has been introduced to image segmentation in recent years. Liang @cite_6 separated natural image with clear boundaries into different disjoint superpixels according to raw RGB pixels, then employed RNN to capture relations among superpixels. Cai @cite_7 used RNN to capture the relations among adjacent slices. We claim that our method is fundamentally different from these previous ones: the point in our method is just an indicator of the object; We capture the inside-outside changing trends with overlapped patches (which may contain both foreground and background) to determine the blurry boundary. Besides, our ConvRNN could be embedded into different levels of convnet instead of only the last few layers.
@cite_14 @cite_13 @cite_7 @cite_6
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Pixel-level labelling tasks, such as semantic segmentation, play a central role in image understanding. Recent approaches have attempted to harness the capabilities of deep learning techniques for image recognition to tackle pixel-level labelling tasks. One central issue in this methodology is the limited capacity of deep learning techniques to delineate visual objects. To solve this problem, we introduce a new form of convolutional neural network that combines the strengths of Convolutional Neural Networks (CNNs) and Conditional Random Fields (CRFs)-based probabilistic graphical modelling. To this end, we formulate Conditional Random Fields with Gaussian pairwise potentials and mean-field approximate inference as Recurrent Neural Networks. This network, called CRF-RNN, is then plugged in as a part of a CNN to obtain a deep network that has desirable properties of both CNNs and CRFs. Importantly, our system fully integrates CRF modelling with CNNs, making it possible to train the whole deep network end-to-end with the usual back-propagation algorithm, avoiding offline post-processing methods for object delineation. We apply the proposed method to the problem of semantic image segmentation, obtaining top results on the challenging Pascal VOC 2012 segmentation benchmark. Recently, deep convolutional neural networks (DCNNs) have significantly promoted the development of semantic image segmentation. However, previous works on learning the segmentation network often rely on a large number of ground-truths with pixel-level annotations, which usually require considerable human effort. In this paper, we explore a more challenging problem by learning to segment under image-level annotations. Specifically, our framework consists of two components. First, reliable hypotheses based localization maps are generated by incorporating the hypotheses-aware classification and cross-image contextual refinement. Second, the segmentation network can be trained in a supervised manner by these generated localization maps. We explore two network training strategies for achieving good segmentation performance. For the first strategy, a novel multi-label cross-entropy loss is proposed to train the network by directly using multiple localization maps for all classes, where each pixel contributes to each class with different weights. For the second strategy, the rough segmentation mask can be inferred from the localization maps, and then the network is optimized based on the single-label cross-entropy loss with the produced masks. We evaluate our methods on the PASCAL VOC 2012 segmentation benchmark. Extensive experimental results demonstrate the effectiveness of the proposed methods compared with the state-of-the-arts. HighlightsLocalization map generation is proposed by using the hypothesis-based classification.A novel multi-label loss is proposed to train the network based on localization maps.An effective method is proposed to predict the rough mask of the given training image.Our methods achieve new state-of-the-art results on PASCAL VOC 2012 benchmark. Over the last years, deep convolutional neural networks (ConvNets) have transformed the field of computer vision thanks to their unparalleled capacity to learn high level semantic image features. However, in order to successfully learn those features, they usually require massive amounts of manually labeled data, which is both expensive and impractical to scale. Therefore, unsupervised semantic feature learning, i.e., learning without requiring manual annotation effort, is of crucial importance in order to successfully harvest the vast amount of visual data that are available today. In our work we propose to learn image features by training ConvNets to recognize the 2d rotation that is applied to the image that it gets as input. We demonstrate both qualitatively and quantitatively that this apparently simple task actually provides a very powerful supervisory signal for semantic feature learning. We exhaustively evaluate our method in various unsupervised feature learning benchmarks and we exhibit in all of them state-of-the-art performance. Specifically, our results on those benchmarks demonstrate dramatic improvements w.r.t. prior state-of-the-art approaches in unsupervised representation learning and thus significantly close the gap with supervised feature learning. For instance, in PASCAL VOC 2007 detection task our unsupervised pre-trained AlexNet model achieves the state-of-the-art (among unsupervised methods) mAP of 54.4 that is only 2.4 points lower from the supervised case. We get similarly striking results when we transfer our unsupervised learned features on various other tasks, such as ImageNet classification, PASCAL classification, PASCAL segmentation, and CIFAR-10 classification. The code and models of our paper will be published on: this https URL . Fully convolutional networks (FCN) have achieved great success in human parsing in recent years. In conventional human parsing tasks, pixel-level labeling is required for guiding the training, which usually involves enormous human labeling efforts. To ease the labeling efforts, we propose a novel weakly supervised human parsing method which only requires simple object keypoint annotations for learning. We develop an iterative learning method to generate pseudo part segmentation masks from keypoint labels. With these pseudo masks, we train an FCN network to output pixel-level human parsing predictions. Furthermore, we develop a correlation network to perform joint prediction of part and object segmentation masks and improve the segmentation performance. The experiment results show that our weakly supervised method is able to achieve very competitive human parsing results. Despite our method only uses simple keypoint annotations for learning, we are able to achieve comparable performance with fully supervised methods which use the expensive pixel-level annotations.