Introduction. Case Based Reasoning (CBR) is an emerg- ing decision making paradigm in medical research where new cases are solved relying on previously solved similar cases. Usually, a database of solved cases is provided, and every case is described through a set of attributes (inputs) and a label (output). Extracting useful information from this database can help the CBR system providing more reliable results on the yet to be solved cases. Objective. For that purpose we suggest a general frame- work where a CBR system, viz. K-Nearest Neighbor (K-NN) algorithm, is combined with various information obtained from a Logistic Regression (LR) model. Methods. LR is applied, on the case database, to assign weights to the attributes as well as the solved cases. Thus, five possible decision making systems based on K-NN and or LR were identified: a standalone K-NN, a standalone LR and three soft K-NN algorithms that rely on the weights based on the results of the LR. The evaluation of the described approaches is performed in the field of renal transplant access waiting list. Results and conclusion. The results show that our suggested approach, where the K-NN algorithm relies on both weighted attributes and cases, can efficiently deal with non relevant attributes, whereas the four other approaches suffer from this kind of noisy setups. The robustness of this approach suggests interesting perspectives for medical problem solving tools using CBR methodology.
As for Chuang s paper, the author points out classification improvements relying on Hybrid CBR approach compared to a standalone CBR. Huang's publication also compares several kinds of hybrid approaches: a neural network with or without fuzzy logic and two hybrid CBR systems, one combining CBR with a decision tree and one combining CBR with LM. The neural networks show superior performances, but the authors emphasized rapidity of cases retrieval and the more easily interpretable results of CBR methodology. In the present study, the CBR hybrid approaches did not show significant improvements for patient classification, compared to standalone CBR approach. However, the hybrid CBR system combing both attribute weighting and case weighting seems to be very robust to artifacts in the database that might occur in all realistic scenarios. From our point of view, this interesting observation provides new perspectives for future CBR system, particularly for integrating CBR systems into large and unspecific knowledge database as electronic health records @cite_8 @cite_7 .
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This paper proposes an effective segmentation-free approach using a hybrid neural network hidden Markov model (NN-HMM) for offline handwritten Chinese text recognition (HCTR). In the general Bayesian framework, the handwritten Chinese text line is sequentially modeled by HMMs with each representing one character class, while the NN-based classifier is adopted to calculate the posterior probability of all HMM states. The key issues in feature extraction, character modeling, and language modeling are comprehensively investigated to show the effectiveness of NN-HMM framework for offline HCTR. First, a conventional deep neural network (DNN) architecture is studied with a well-designed feature extractor. As for the training procedure, the label refinement using forced alignment and the sequence training can yield significant gains on top of the frame-level cross-entropy criterion. Second, a deep convolutional neural network (DCNN) with automatically learned discriminative features demonstrates its superiority to DNN in the HMM framework. Moreover, to solve the challenging problem of distinguishing quite confusing classes due to the large vocabulary of Chinese characters, NN-based classifier should output 19900 HMM states as the classification units via a high-resolution modeling within each character. On the ICDAR 2013 competition task of CASIA-HWDB database, DNN-HMM yields a promising character error rate (CER) of 5.24 by making a good trade-off between the computational complexity and recognition accuracy. To the best of our knowledge, DCNN-HMM can achieve a best published CER of 3.53 . Electronic patient records (EPRs) contain a wealth of patient-related data and capture clinical problem-solving experiences and decisions. Excelicare is such a system which is also a platform for the national generic clinical system in the UK. Objective: This paper presents, ExcelicareCBR, a case-based reasoning (CBR) system which has been developed to complement Excelicare. Objective of this work is to integrate CBR to support clinical decision making by harnessing electronic patient records for clinical experience reuse. Methods: CBR is a proven problem solving methodology in which past solutions are reused to solve new problems. A key challenge that we address in this paper is how to extract and represent a case from an EPR. Using an example from the lung cancer domain we demonstrate our generic case representation approach where Excelicare fields are mapped to case features. Once the case base is populated with cases containing data from the EPRs database a standard weighted k-nearest neighbour algorithm combined with a genetic algorithm based feature weighting mechanism is used for case retrieval and reuse. Conclusions: We conclude that incorporating case authoring functionality and a generic retrieval mechanism were key to successful integration of ExcelicareCBR. This paper also demonstrates how the application of CBR can enable sharing of lessons learned through the retrieval and reuse of EPRs captured as cases in a case base. The resources allocated for software quality assurance and improvement have not increased with the ever-increasing need for better software quality. A targeted software quality inspection can detect faulty modules and reduce the number of faults occurring during operations. We present a software fault prediction modeling approach with case-based reasoning (CBR), a part of the computational intelligence field focusing on automated reasoning processes. A CBR system functions as a software fault prediction model by quantifying, for a module under development, the expected number of faults based on similar modules that were previously developed. Such a system is composed of a similarity function, the number of nearest neighbor cases used for fault prediction, and a solution algorithm. The selection of a particular similarity function and solution algorithm may affect the performance accuracy of a CBR-based software fault prediction system. This paper presents an empirical study investigating the effects of using three different similarity functions and two different solution algorithms on the prediction accuracy of our CBR system. The influence of varying the number of nearest neighbor cases on the performance accuracy is also explored. Moreover, the benefits of using metric-selection procedures for our CBR system is also evaluated. Case studies of a large legacy telecommunications system are used for our analysis. It is observed that the CBR system using the Mahalanobis distance similarity function and the inverse distance weighted solution algorithm yielded the best fault prediction. In addition, the CBR models have better performance than models based on multiple linear regression. Deep learning methods such as convolutional neural networks (CNNs) can deliver highly accurate classification results when provided with large enough data sets and respective labels. However, using CNNs along with limited labeled data can be problematic, as this leads to extensive overfitting. In this letter, we propose a novel method by considering a pretrained CNN designed for tackling an entirely different classification problem, namely, the ImageNet challenge, and exploit it to extract an initial set of representations. The derived representations are then transferred into a supervised CNN classifier, along with their class labels, effectively training the system. Through this two-stage framework, we successfully deal with the limited-data problem in an end-to-end processing scheme. Comparative results over the UC Merced Land Use benchmark prove that our method significantly outperforms the previously best stated results, improving the overall accuracy from 83.1 up to 92.4 . Apart from statistical improvements, our method introduces a novel feature fusion algorithm that effectively tackles the large data dimensionality by using a simple and computationally efficient approach.