In Traditional Chinese Medicine (TCM), facial features are important basis for diagnosis and treatment. A doctor of TCM can prescribe according to a patient's physical indicators such as face, tongue, voice, symptoms, pulse. Previous works analyze and generate prescription according to symptoms. However, research work to mine the association between facial features and prescriptions has not been found for the time being. In this work, we try to use deep learning methods to mine the relationship between the patient's face and herbal prescriptions (TCM prescriptions), and propose to construct convolutional neural networks that generate TCM prescriptions according to the patient's face image. It is a novel and challenging job. In order to mine features from different granularities of faces, we design a multi-scale convolutional neural network based on three-grained face, which mines the patient's face information from the organs, local regions, and the entire face. Our experiments show that convolutional neural networks can learn relevant information from face to prescribe, and the multi-scale convolutional neural networks based on three-grained face perform better.
Deep learning and convolutional neural network have become popular topics in medical image processing. There are already a lot of research works that apply deep learning to medical image processing. In terms of disease classification, there are studies on breast cancer image classification @cite_36 @cite_37 , lung pattern classification @cite_44 , Alzheimer’s disease classification @cite_12 . In the detection of lesion targets and diseases, there are cancerous tissue recognition @cite_19 , detecting cardiovascular disease @cite_1 , and melanoma recognition @cite_38 . In the segmentation of organs and substructures, there are studies on skin lesion segmentation @cite_13 , microvasculature segmentation of arterioles @cite_41 , tumor segmentation @cite_11 . In addition, there are many other applications, such as studies of visual attention of patients with Dementia @cite_4 , diagnosis of cirrhosis stage @cite_0 , constructing brain maps @cite_22 .
@cite_38 @cite_37 @cite_4 @cite_22 @cite_36 @cite_41 @cite_1 @cite_44 @cite_19 @cite_0 @cite_13 @cite_12 @cite_11
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Abstract Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such datasets in the medical domain remains a challenge. In this paper, we present methods for generating synthetic medical images using recently presented deep learning Generative Adversarial Networks (GANs). Furthermore, we show that generated medical images can be used for synthetic data augmentation, and improve the performance of CNN for medical image classification. Our novel method is demonstrated on a limited dataset of computed tomography (CT) images of 182 liver lesions (53 cysts, 64 metastases and 65 hemangiomas). We first exploit GAN architectures for synthesizing high quality liver lesion ROIs. Then we present a novel scheme for liver lesion classification using CNN. Finally, we train the CNN using classic data augmentation and our synthetic data augmentation and compare performance. In addition, we explore the quality of our synthesized examples using visualization and expert assessment. The classification performance using only classic data augmentation yielded 78.6 sensitivity and 88.4 specificity. By adding the synthetic data augmentation the results increased to 85.7 sensitivity and 92.4 specificity. We believe that this approach to synthetic data augmentation can generalize to other medical classification applications and thus support radiologists’ efforts to improve diagnosis. Deep learning methods for image analysis have shown impressive performance in recent years. In this paper, we present deep learning based approaches to solve two problems in skin lesion analysis using a dermoscopic image containing skin tumor. In the first problem, we use a fully convolutional-deconvolutional architecture to automatically segment skin tumor from the surrounding skin. In the second problem, we use a simple convolutional neural network and VGG-16 architecture using transfer learning to address the two different tasks in skin tumor classification. The proposed models are trained and evaluated on standard benchmark datasets from the International Skin Imaging Collaboration (ISIC) 2017 Challenge, which consists of 2000 training samples and 600 testing samples. The result shows that the proposed methods achieve promising performances. In the first problem, the average value of Jaccard index for lesion segmentation using fully convolutional-deconvolutional architecture is 0.507. In the second problem, the values of area under the receiver operating characteristic curve (AUC) on two different lesion classifications using VGG16 with transfer learning are 0.763 and 0.869, respectively; the average value of AUC in two tasks is 0.816. Abstract Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks. Concise overviews are provided of studies per application area: neuro, retinal, pulmonary, digital pathology, breast, cardiac, abdominal, musculoskelet al. We end with a summary of the current state-of-the-art, a critical discussion of open challenges and directions for future research. In this work, we examine the strength of deep learning approaches for pathology detection in chest radiographs. Convolutional neural networks (CNN) deep architecture classification approaches have gained popularity due to their ability to learn mid and high level image representations. We explore the ability of CNN learned from a non-medical dataset to identify different types of pathologies in chest x-rays. We tested our algorithm on a 433 image dataset. The best performance was achieved using CNN and GIST features. We obtained an area under curve (AUC) of 0.87–0.94 for the different pathologies. The results demonstrate the feasibility of detecting pathology in chest x-rays using deep learning approaches based on non-medical learning. This is a first-of-its-kind experiment that shows that Deep learning with ImageNet, a large scale non-medical image database may be a good substitute to domain specific representations, which are yet to be available, for general medical image recognition tasks.