Estimating vaccination uptake is an integral part of ensuring public health. It was recently shown that vaccination uptake can be estimated automatically from web data, instead of slowly collected clinical records or population surveys. All prior work in this area assumes that features of vaccination uptake collected from the web are temporally regular. We present the first ever method to remove this assumption from vaccination uptake estimation: our method dynamically adapts to temporal fluctuations in time series web data used to estimate vaccination uptake. We show our method to outperform the state of the art compared to competitive baselines that use not only web data but also curated clinical data. This performance improvement is more pronounced for vaccines whose uptake has been irregular due to negative media attention (HPV-1 and HPV-2), problems in vaccine supply (DiTeKiPol), and targeted at children of 12 years old (whose vaccination is more irregular compared to younger children).
Linear models have been used previously to estimate health events, for instance by combining data from multiple sources with an ensemble of decision trees @cite_4 , or, closer to our work, by using query frequencies for influenza like illness @cite_5 or vaccination uptake estimation @cite_2 . These approaches are designed for stationary time-series analysis, i.e. they assume data is generated by a stationary stochastic process. Our motivation is that vaccination uptake often does not follow stationary seasonal patterns. External events such as disease outbreaks, suspicion of adverse effects, or temporary vaccine shortages can alter uptake patterns for shorter or longer periods of time. Hence, while historical data is a good estimator in stable periods, as shown in @cite_2 , we reason that adapting the estimation to any unstability can reduce estimation error. We experimentally confirm this on all official children vaccines data used in Denmark between 2011 - 2016.
@cite_5 @cite_4 @cite_2
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User-generated content can assist epidemiological surveillance in the early detection and prevalence estimation of infectious diseases, such as influenza. Google Flu Trends embodies the first public platform for transforming search queries to indications about the current state of flu in various places all over the world. However, the original model significantly mispredicted influenza-like illness rates in the US during the 2012–13 flu season. In this work, we build on the previous modeling attempt, proposing substantial improvements. Firstly, we investigate the performance of a widely used linear regularized regression solver, known as the Elastic Net. Then, we expand on this model by incorporating the queries selected by the Elastic Net into a nonlinear regression framework, based on a composite Gaussian Process. Finally, we augment the query-only predictions with an autoregressive model, injecting prior knowledge about the disease. We assess predictive performance using five consecutive flu seasons spanning from 2008 to 2013 and qualitatively explain certain shortcomings of the previous approach. Our results indicate that a nonlinear query modeling approach delivers the lowest cumulative nowcasting error, and also suggest that query information significantly improves autoregressive inferences, obtaining state-of-the-art performance. Estimating vaccination uptake is an integral part of ensuring public health. It was recently shown that vaccination uptake can be estimated automatically from web data, instead of slowly collected clinical records or population surveys. All prior work in this area assumes that features of vaccination uptake collected from the web are temporally regular. We present the first ever method to remove this assumption from vaccination uptake estimation: our method dynamically adapts to temporal fluctuations in time series web data used to estimate vaccination uptake. We show our method to outperform the state of the art compared to competitive baselines that use not only web data but also curated clinical data. This performance improvement is more pronounced for vaccines whose uptake has been irregular due to negative media attention (HPV-1 and HPV-2), problems in vaccine supply (DiTeKiPol), and targeted at children of 12 years old (whose vaccination is more irregular compared to younger children). We present a method that uses ensemble learning to combine clinical and web-mined time-series data in order to predict future vaccination uptake. The clinical data is official vaccination registries, and the web data is query frequencies collected from Google Trends. Experiments with official vaccine records show that our method predicts vaccination uptake effectively (4.7 Root Mean Squared Error). Whereas performance is best when combining clinical and web data, using solely web data yields comparative performance. To our knowledge, this is the first study to predict vaccination uptake using web data (with and without clinical data). We present a method that uses ensemble learning to combine clinical and web-mined time-series data in order to predict future vaccination uptake. The clinical data is official vaccination registries, and the web data is query frequencies collected from Google Trends. Experiments with official vaccine records show that our method predicts vaccination uptake effectively (4.7 Root Mean Squared Error). Whereas performance is best when combining clinical and web data, using solely web data yields comparative performance. To our knowledge, this is the first study to predict vaccination uptake using web data (with and without clinical data).