Examining blood microscopic images for leukemia is necessary when expensive equipment for flow cytometry is unavailable. Automated systems can ease the burden on medical experts for performing this examination and may be especially helpful to quickly screen a large number of patients. We present a simple, yet effective classification approach using a ResNeXt convolutional neural network with Squeeze-and-Excitation modules. The approach was evaluated in the C-NMC online challenge and achieves a weighted F1-score of 88.91 on the test set. Code is available at this https URL
@cite_9 classify ALL subtypes on a private dataset of 330 images using a pre-trained AlexNet and fine-tuning. Shafique and Tehsin @cite_13 classify ALL subtypes on ALL-IDB augmented with 50 private images, also using a pre-trained AlexNet and fine-tuning. @cite_17 classify ALL on ALL-IDB using a number of different pre-trained CNNs as fixed feature extractors. From these CNN features the most informative ones are selected using PCA and finally classification is performed with an ensemble of SVM, MLP, and random forest.
@cite_9 @cite_13 @cite_17
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In image classification, visual separability between different object categories is highly uneven, and some categories are more difficult to distinguish than others. Such difficult categories demand more dedicated classifiers. However, existing deep convolutional neural networks (CNN) are trained as flat N-way classifiers, and few efforts have been made to leverage the hierarchical structure of categories. In this paper, we introduce hierarchical deep CNNs (HD-CNNs) by embedding deep CNNs into a category hierarchy. An HD-CNN separates easy classes using a coarse category classifier while distinguishing difficult classes using fine category classifiers. During HD-CNN training, component-wise pretraining is followed by global finetuning with a multinomial logistic loss regularized by a coarse category consistency term. In addition, conditional executions of fine category classifiers and layer parameter compression make HD-CNNs scalable for large-scale visual recognition. We achieve state-of-the-art results on both CIFAR100 and large-scale ImageNet 1000-class benchmark datasets. In our experiments, we build up three different HD-CNNs and they lower the top-1 error of the standard CNNs by 2.65 , 3.1 and 1.1 , respectively. The availability of large-scale annotated data and the uneven separability of different data categories have become two major impediments of deep learning for image classification. In this paper, we present a semi-supervised hierarchical convolutional neural network (SS-HCNN) to address these two challenges. A large-scale unsupervised maximum margin clustering technique is designed, which splits images into a number of hierarchical clusters iteratively to learn cluster-level CNNs at parent nodes and category-level CNNs at leaf nodes. The splitting uses the similarity of CNN features to group visually similar images into the same cluster, which relieves the uneven data separability constraint. With the hierarchical cluster-level CNNs capturing certain high-level image category information, the category-level CNNs can be trained with a small amount of labeled images, and this relieves the data annotation constraint. A novel cluster splitting criterion is also designed, which automatically terminates the image clustering in the tree hierarchy. The proposed SS-HCNN has been evaluated on the CIFAR-100 and ImageNet classification datasets. The experiments show that the SS-HCNN trained using a portion of labeled training images can achieve comparable performance with other fully trained CNNs using all labeled images. Additionally, the SS-HCNN trained using all labeled images clearly outperforms other fully trained CNNs. Remarkable progress has been made in image recognition, primarily due to the availability of large-scale annotated datasets and deep convolutional neural networks (CNNs). CNNs enable learning data-driven, highly representative, hierarchical image features from sufficient training data. However, obtaining datasets as comprehensively annotated as ImageNet in the medical imaging domain remains a challenge. There are currently three major techniques that successfully employ CNNs to medical image classification: training the CNN from scratch, using off-the-shelf pre-trained CNN features, and conducting unsupervised CNN pre-training with supervised fine-tuning. Another effective method is transfer learning, i.e., fine-tuning CNN models pre-trained from natural image dataset to medical image tasks. In this paper, we exploit three important, but previously understudied factors of employing deep convolutional neural networks to computer-aided detection problems. We first explore and evaluate different CNN architectures. The studied models contain 5 thousand to 160 million parameters, and vary in numbers of layers. We then evaluate the influence of dataset scale and spatial image context on performance. Finally, we examine when and why transfer learning from pre-trained ImageNet (via fine-tuning) can be useful. We study two specific computer-aided detection (CADe) problems, namely thoraco-abdominal lymph node (LN) detection and interstitial lung disease (ILD) classification. We achieve the state-of-the-art performance on the mediastinal LN detection, and report the first five-fold cross-validation classification results on predicting axial CT slices with ILD categories. Our extensive empirical evaluation, CNN model analysis and valuable insights can be extended to the design of high performance CAD systems for other medical imaging tasks. Convolutional Neural Networks (CNN) have revolutionized perception for color images, and their application to sonar images has also obtained good results. But in general CNNs are difficult to train without a large dataset, need manual tuning of a considerable number of hyperparameters, and require many careful decisions by a designer. In this work, we evaluate three common decisions that need to be made by a CNN designer, namely the performance of transfer learning, the effect of object image size and the relation between training set size. We evaluate three CNN models, namely one based on LeNet, and two based on the Fire module from SqueezeNet. Our findings are: Transfer learning with an SVM works very well, even when the train and transfer sets have no classes in common, and high classification performance can be obtained even when the target dataset is small. The ADAM optimizer combined with Batch Normalization can make a high accuracy CNN classifier, even with small image sizes (16 pixels). At least 50 samples per class are required to obtain 90 test accuracy, and using Dropout with a small dataset helps improve performance, but Batch Normalization is better when a large dataset is available.