In current clinical practice, electroencephalograms (EEG) are reviewed and analyzed by well-trained neurologists to provide supports for therapeutic decisions. The way of manual reviewing is labor-intensive and error prone. Automatic and accurate seizure nonseizure classification methods are needed. One major problem is that the EEG signals for seizure state and nonseizure state exhibit considerable variations. In order to capture essential seizure features, this paper integrates an emerging deep learning model, the independently recurrent neural network (IndRNN), with a dense structure and an attention mechanism to exploit temporal and spatial discriminating features and overcome seizure variabilities. The dense structure is to ensure maximum information flow between layers. The attention mechanism is to capture spatial features. Evaluations are performed in cross-validation experiments over the noisy CHB-MIT data set. The obtained average sensitivity, specificity and precision of 88.80 , 88.60 and 88.69 are better than using the current state-of-the-art methods. In addition, we explore how the segment length affects the classification performance. Thirteen different segment lengths are assessed, showing that the classification performance varies over the segment lengths, and the maximal fluctuating margin is more than 4 . Thus, the segment length is an important factor influencing the classification performance.
presented a recurrent convolutional neural network to capture spectral, spatial and temporal features of seizures @cite_26 . EEG signals were firstly transformed into images. Created images were fed to CNN. Output vectors of the CNN were organized to be sequences in the chronological order. The sequences were passed on to the bidirectional RNN to make classification. Both patient-specific experiments and cross-patient experiments were performed. In the cross-patient testing, the obtained average sensitivity was 85 proposed a deep recurrent architecture by combining cellular neural network with bidirectional RNN @cite_5 . The bidirectional RNN was deployed into each cell of the cellular neural network to extract temporal features in the forward and the backward directions. Each cell interacts with its neighboring cells to extract local spatial-temporal features. The method was evaluated in patient-specific experiments over five patients from CHB-MIT. The obtained sensitivities are 100 explored two kinds of neural networks over TUH EEG Corpus @cite_28 . Their experimental results showed that convolutional LSTM network outperformed convolutional GRU network. Different initialization and regularization methods were also tested.
@cite_28 @cite_5 @cite_26
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Recurrent Neural Networks (RNNs) with sophisticated units that implement a gating mechanism have emerged as powerful technique for modeling sequential signals such as speech or electroencephalography (EEG). The latter is the focus on this paper. A significant big data resource, known as the TUH EEG Corpus (TUEEG), has recently become available for EEG research, creating a unique opportunity to evaluate these recurrent units on the task of seizure detection. In this study, we compare two types of recurrent units: long short-term memory units (LSTM) and gated recurrent units (GRU). These are evaluated using a state of the art hybrid architecture that integrates Convolutional Neural Networks (CNNs) with RNNs. We also investigate a variety of initialization methods and show that initialization is crucial since poorly initialized networks cannot be trained. Furthermore, we explore regularization of these convolutional gated recurrent networks to address the problem of overfitting. Our experiments revealed that convolutional LSTM networks can achieve significantly better performance than convolutional GRU networks. The convolutional LSTM architecture with proper initialization and regularization delivers 30 sensitivity at 6 false alarms per 24 hours. We present and evaluate the capacity of a deep neural network to learn robust features from EEG to automatically detect seizures. This is a challenging problem because seizure manifestations on EEG are extremely variable both inter- and intra-patient. By simultaneously capturing spectral, temporal and spatial information our recurrent convolutional neural network learns a general spatially invariant representation of a seizure. The proposed approach exceeds significantly previous results obtained on cross-patient classifiers both in terms of sensitivity and false positive rate. Furthermore, our model proves to be robust to missing channel and variable electrode montage. In existing convolutional neural networks (CNNs), both convolution and pooling are locally performed for image regions separately, no contextual dependencies between different image regions have been taken into consideration. Such dependencies represent useful spatial structure information in images. Whereas recurrent neural networks (RNNs) are designed for learning contextual dependencies among sequential data by using the recurrent (feedback) connections. In this work, we propose the convolutional recurrent neural network (C-RNN), which learns the spatial dependencies between image regions to enhance the discriminative power of image representation. The C-RNN is trained in an end-to-end manner from raw pixel images. CNN layers are firstly processed to generate middle level features. RNN layer is then learned to encode spatial dependencies. The C-RNN can learn better image representation, especially for images with obvious spatial contextual dependencies. Our method achieves competitive performance on ILSVRC 2012, SUN 397, and MIT indoor. We adopt Convolutional Neural Networks (CNN) to learn discriminative features for local patch classification. We further introduce quaddirectional 2D Recurrent Neural Networks to model the long range dependencies among pixels. Our quaddirectional 2D-RNN is able to embed the global image context into the compact local representation, which significantly enhance their discriminative power. Our experiments demonstrate that the integration of CNN and quaddirectional 2D-RNN achieves very promising results which are comparable to state-of-the-art on real-world image labeling benchmarks.