Contextual word embedding models such as ELMo (, 2018) and BERT (, 2018) have dramatically improved performance for many natural language processing (NLP) tasks in recent months. However, these models have been minimally explored on specialty corpora, such as clinical text; moreover, in the clinical domain, no publicly-available pre-trained BERT models yet exist. In this work, we address this need by exploring and releasing BERT models for clinical text: one for generic clinical text and another for discharge summaries specifically. We demonstrate that using a domain-specific model yields performance improvements on three common clinical NLP tasks as compared to nonspecific embeddings. These domain-specific models are not as performant on two clinical de-identification tasks, and argue that this is a natural consequence of the differences between de-identified source text and synthetically non de-identified task text.
@cite_1 , released in late February 2019, train a clinical note corpus BERT language model and uses complex task-specific models to yield improvements over both traditional embeddings and ELMo embeddings on the i2b2 2010 and 2012 tasks @cite_9 @cite_14 and the SemEval 2014 task 7 @cite_11 and 2015 task 14 @cite_18 tasks, establishing new state-of-the-art results on all four corpora. However, this work neither releases their embeddings for the larger community nor examines the performance opportunities offered by fine-tuning BioBERT with clinical text or by training note-type specific embedding models, as we do.
@cite_18 @cite_14 @cite_9 @cite_1 @cite_11
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This paper describes the SemEval-2014, Task 7 on the Analysis of Clinical Text and presents the evaluation results. It focused on two subtasks: (i) identification (Task A) and (ii) normalization (Task B) of diseases and disorders in clinical reports as annotated in the Shared Annotated Resources (ShARe) 1 corpus. This task was a follow-up to the ShARe CLEF eHealth 2013 shared task, subtasks 1a and 1b, 2 but using a larger test set. A total of 21 teams competed in Task A, and 18 of those also participated in Task B. For Task A, the best system had a strict F1-score of 81.3, with a precision of 84.3 and recall of 78.6. For Task B, the same group had the best strict accuracy of 74.1. The organizers have made the text corpora, annotations, and evaluation tools available for future research and development at the shared task website. 3 Neural network-based representations ("embeddings") have dramatically advanced natural language processing (NLP) tasks, including clinical NLP tasks such as concept extraction. Recently, however, more advanced embedding methods and representations (e.g., ELMo, BERT) have further pushed the state-of-the-art in NLP, yet there are no common best practices for how to integrate these representations into clinical tasks. The purpose of this study, then, is to explore the space of possible options in utilizing these new models for clinical concept extraction, including comparing these to traditional word embedding methods (word2vec, GloVe, fastText). Both off-the-shelf, open-domain embeddings and pre-training clinical embeddings from MIMIC-III are evaluated. We explore a battery of embedding methods consisting of traditional word embeddings and contextual embeddings, and compare these on four concept extraction corpora: i2b2 2010, i2b2 2012, SemEval 2014, and SemEval 2015. We also analyze the impact of the pre-training time of a large language model like ELMo or BERT on the extraction performance. Finally, we present an intuitive way to understand the semantic information encoded by contextual embeddings. Contextual embeddings pre-trained on a large clinical corpus achieves new state-of-the-art performances across all concept extraction tasks. The best-performing model outperforms all state-of-the-art methods with respective F1-measures of 90.25, 93.18 (partial), 80.74, and 81.65. We demonstrate the potential of contextual embeddings through the state-of-the-art performance these methods achieve on clinical concept extraction. Additionally, we demonstrate contextual embeddings encode valuable semantic information not accounted for in traditional word representations. Recently, neural models pretrained on a language modeling task, such as ELMo (, 2017), OpenAI GPT (, 2018), and BERT (, 2018), have achieved impressive results on various natural language processing tasks such as question-answering and natural language inference. In this paper, we describe a simple re-implementation of BERT for query-based passage re-ranking. Our system is the state of the art on the TREC-CAR dataset and the top entry in the leaderboard of the MS MARCO passage retrieval task, outperforming the previous state of the art by 27 (relative) in MRR@10. The code to reproduce our results is available at this https URL Biomedical text mining is becoming increasingly important as the number of biomedical documents rapidly grows. With the progress in machine learning, extracting valuable information from biomedical literature has gained popularity among researchers, and deep learning has boosted the development of effective biomedical text mining models. However, as deep learning models require a large amount of training data, applying deep learning to biomedical text mining is often unsuccessful due to the lack of training data in biomedical fields. Recent researches on training contextualized language representation models on text corpora shed light on the possibility of leveraging a large number of unannotated biomedical text corpora. We introduce BioBERT (Bidirectional Encoder Representations from Transformers for Biomedical Text Mining), which is a domain specific language representation model pre-trained on large-scale biomedical corpora. Based on the BERT architecture, BioBERT effectively transfers the knowledge from a large amount of biomedical texts to biomedical text mining models with minimal task-specific architecture modifications. While BERT shows competitive performances with previous state-of-the-art models, BioBERT significantly outperforms them on the following three representative biomedical text mining tasks: biomedical named entity recognition (0.51 absolute improvement), biomedical relation extraction (3.49 absolute improvement), and biomedical question answering (9.61 absolute improvement). We make the pre-trained weights of BioBERT freely available at this https URL, and the source code for fine-tuning BioBERT available at this https URL.