Synthesized medical images have several important applications, e.g., as an intermedium in cross-modality image registration and as supplementary training samples to boost the generalization capability of a classifier. Especially, synthesized computed tomography (CT) data can provide X-ray attenuation map for radiation therapy planning. In this work, we propose a generic cross-modality synthesis approach with the following targets: 1) synthesizing realistic looking 3D images using unpaired training data, 2) ensuring consistent anatomical structures, which could be changed by geometric distortion in cross-modality synthesis and 3) improving volume segmentation by using synthetic data for modalities with limited training samples. We show that these goals can be achieved with an end-to-end 3D convolutional neural network (CNN) composed of mutually-beneficial generators and segmentors for image synthesis and segmentation tasks. The generators are trained with an adversarial loss, a cycle-consistency loss, and also a shape-consistency loss, which is supervised by segmentors, to reduce the geometric distortion. From the segmentation view, the segmentors are boosted by synthetic data from generators in an online manner. Generators and segmentors prompt each other alternatively in an end-to-end training fashion. With extensive experiments on a dataset including a total of 4,496 CT and magnetic resonance imaging (MRI) cardiovascular volumes, we show both tasks are beneficial to each other and coupling these two tasks results in better performance than solving them exclusively.
In computer vision, recent image-to-image translation is formulated as a pixel-to-pixel mapping using encoder-decoder CNNs @cite_31 @cite_35 @cite_29 @cite_20 @cite_35 @cite_23 @cite_14 . Several studies have explored cross-modality translation for medical images, using sparse coding @cite_39 @cite_27 , GANs @cite_24 @cite_13 , CNN @cite_32 , etc. GANs have attracted wide interests in helping addressing such tasks to generate high-quality, less blurry results @cite_15 @cite_26 @cite_38 @cite_25 . More recent studies apply pixel-to-pixel GANs for brain MRI to CT image translation @cite_24 @cite_3 and retinal vessel annotation to image translation @cite_28 . However, these methods presume targeting images have paired cross-domain data. Learning from unpaired cross-domain data is an attractive yet not well explored problem @cite_27 @cite_16 .
@cite_35 @cite_38 @cite_14 @cite_26 @cite_15 @cite_28 @cite_29 @cite_32 @cite_3 @cite_39 @cite_24 @cite_27 @cite_23 @cite_31 @cite_16 @cite_13 @cite_25 @cite_20
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Conditional Generative Adversarial Networks (GANs) for cross-domain image-to-image translation have made much progress recently. Depending on the task complexity, thousands to millions of labeled image pairs are needed to train a conditional GAN. However, human labeling is expensive, even impractical, and large quantities of data may not always be available. Inspired by dual learning from natural language translation, we develop a novel dual-GAN mechanism, which enables image translators to be trained from two sets of unlabeled images from two domains. In our architecture, the primal GAN learns to translate images from domain U to those in domain V, while the dual GAN learns to invert the task. The closed loop made by the primal and dual tasks allows images from either domain to be translated and then reconstructed. Hence a loss function that accounts for the reconstruction error of images can be used to train the translators. Experiments on multiple image translation tasks with unlabeled data show considerable performance gain of DualGAN over a single GAN. For some tasks, DualGAN can even achieve comparable or slightly better results than conditional GAN trained on fully labeled data. Image-to-image translation tasks have been widely investigated with Generative Adversarial Networks (GANs) and dual learning. However, existing models lack the ability to control the translated results in the target domain and their results usually lack of diversity in the sense that a fixed image usually leads to (almost) deterministic translation result. In this paper, we study a new problem, conditional image-to-image translation, which is to translate an image from the source domain to the target domain conditioned on a given image in the target domain. It requires that the generated image should inherit some domain-specific features of the conditional image from the target domain. Therefore, changing the conditional image in the target domain will lead to diverse translation results for a fixed input image from the source domain, and therefore the conditional input image helps to control the translation results. We tackle this problem with unpaired data based on GANs and dual learning. We twist two conditional translation models (one translation from A domain to B domain, and the other one from B domain to A domain) together for inputs combination and reconstruction while preserving domain independent features. We carry out experiments on men's faces from-to women's faces translation and edges to shoes&bags translations. The results demonstrate the effectiveness of our proposed method. Conditional Generative Adversarial Networks (GANs) for cross-domain image-to-image translation have made much progress recently [7, 8, 21, 12, 4, 18]. Depending on the task complexity, thousands to millions of labeled image pairs are needed to train a conditional GAN. However, human labeling is expensive, even impractical, and large quantities of data may not always be available. Inspired by dual learning from natural language translation [23], we develop a novel dual-GAN mechanism, which enables image translators to be trained from two sets of unlabeled images from two domains. In our architecture, the primal GAN learns to translate images from domain U to those in domain V, while the dual GAN learns to invert the task. The closed loop made by the primal and dual tasks allows images from either domain to be translated and then reconstructed. Hence a loss function that accounts for the reconstruction error of images can be used to train the translators. Experiments on multiple image translation tasks with unlabeled data show considerable performance gain of DualGAN over a single GAN. For some tasks, DualGAN can even achieve comparable or slightly better results than conditional GAN trained on fully labeled data. Unsupervised image translation, which aims in translating two independent sets of images, is challenging in discovering the correct correspondences without paired data. Existing works build upon Generative Adversarial Networks (GANs) such that the distribution of the translated images are indistinguishable from the distribution of the target set. However, such set-level constraints cannot learn the instance-level correspondences (e.g. aligned semantic parts in object transfiguration task). This limitation often results in false positives (e.g. geometric or semantic artifacts), and further leads to mode collapse problem. To address the above issues, we propose a novel framework for instance-level image translation by Deep Attention GAN (DA-GAN). Such a design enables DA-GAN to decompose the task of translating samples from two sets into translating instances in a highly-structured latent space. Specifically, we jointly learn a deep attention encoder, and the instance-level correspondences could be consequently discovered through attending on the learned instances. Therefore, the constraints could be exploited on both set-level and instance-level. Comparisons against several state-of-the-arts demonstrate the superiority of our approach, and the broad application capability, e.g, pose morphing, data augmentation, etc., pushes the margin of domain translation problem.1 Unsupervised image translation, which aims in translating two independent sets of images, is challenging in discovering the correct correspondences without paired data. Existing works build upon Generative Adversarial Network (GAN) such that the distribution of the translated images are indistinguishable from the distribution of the target set. However, such set-level constraints cannot learn the instance-level correspondences (e.g. aligned semantic parts in object configuration task). This limitation often results in false positives (e.g. geometric or semantic artifacts), and further leads to mode collapse problem. To address the above issues, we propose a novel framework for instance-level image translation by Deep Attention GAN (DA-GAN). Such a design enables DA-GAN to decompose the task of translating samples from two sets into translating instances in a highly-structured latent space. Specifically, we jointly learn a deep attention encoder, and the instancelevel correspondences could be consequently discovered through attending on the learned instance pairs. Therefore, the constraints could be exploited on both set-level and instance-level. Comparisons against several state-ofthe- arts demonstrate the superiority of our approach, and the broad application capability, e.g, pose morphing, data augmentation, etc., pushes the margin of domain translation problem. Recently, Image-to-Image Translation (IIT) has achieved great progress in image style transfer and semantic context manipulation for images. However, existing approaches require exhaustively labelling training data, which is labor demanding, difficult to scale up, and hard to adapt to a new domain. To overcome such a key limitation, we propose Sparsely Grouped Generative Adversarial Networks (SG-GAN) as a novel approach that can translate images in sparsely grouped datasets where only a few train samples are labelled. Using a one-input multi-output architecture, SG-GAN is well-suited for tackling multi-task learning and sparsely grouped learning tasks. The new model is able to translate images among multiple groups using only a single trained model. To experimentally validate the advantages of the new model, we apply the proposed method to tackle a series of attribute manipulation tasks for facial images as a case study. Experimental results show that SG-GAN can achieve comparable results with state-of-the-art methods on adequately labelled datasets while attaining a superior image translation quality on sparsely grouped datasets is available at https: github.com zhangqianhui SGGAN-tensorflow.. Despite the promising results on paired unpaired image-to-image translation achieved by Generative Adversarial Networks (GANs), prior works often only transfer the low-level information (e.g. color or texture changes), but fail to manipulate high-level semantic meanings (e.g., geometric structure or content) of different object regions. On the other hand, while some researches can synthesize compelling real-world images given a class label or caption, they cannot condition on arbitrary shapes or structures, which largely limits their application scenarios and interpretive capability of model results. In this work, we focus on a more challenging semantic manipulation task, aiming at modifying the semantic meaning of an object while preserving its own characteristics (e.g. viewpoints and shapes), such as cow ( )sheep, motor ( )bicycle, cat ( )dog. To tackle such large semantic changes, we introduce a contrasting GAN (contrast-GAN) with a novel adversarial contrasting objective which is able to perform all types of semantic translations with one category-conditional generator. Instead of directly making the synthesized samples close to target data as previous GANs did, our adversarial contrasting objective optimizes over the distance comparisons between samples, that is, enforcing the manipulated data be semantically closer to the real data with target category than the input data. Equipped with the new contrasting objective, a novel mask-conditional contrast-GAN architecture is proposed to enable disentangle image background with object semantic changes. Extensive qualitative and quantitative experiments on several semantic manipulation tasks on ImageNet and MSCOCO dataset show considerable performance gain by our contrast-GAN over other conditional GANs. It's useful to automatically transform an image from its original form to some synthetic form (style, partial contents, etc.), while keeping the original structure or semantics. We define this requirement as the "image-to-image translation" problem, and propose a general approach to achieve it, based on deep convolutional and conditional generative adversarial networks (GANs), which has gained a phenomenal success to learn mapping images from noise input since 2014. In this work, we develop a two step (unsupervised) learning method to translate images between different domains by using unlabeled images without specifying any correspondence between them, so that to avoid the cost of acquiring labeled data. Compared with prior works, we demonstrated the capacity of generality in our model, by which variance of translations can be conduct by a single type of model. Such capability is desirable in applications like bidirectional translation Deep image translation methods have recently shown excellent results, outputting high-quality images covering multiple modes of the data distribution. There has also been increased interest in disentangling the internal representations learned by deep methods to further improve their performance and achieve a finer control. In this paper, we bridge these two objectives and introduce the concept of cross-domain disentanglement. We aim to separate the internal representation into three parts. The shared part contains information for both domains. The exclusive parts, on the other hand, contain only factors of variation that are particular to each domain. We achieve this through bidirectional image translation based on Generative Adversarial Networks and cross-domain autoencoders, a novel network component. Our model offers multiple advantages. We can output diverse samples covering multiple modes of the distributions of both domains, perform domain-specific image transfer and interpolation, and cross-domain retrieval without the need of labeled data, only paired images. We compare our model to the state-of-the-art in multi-modal image translation and achieve better results for translation on challenging datasets as well as for cross-domain retrieval on realistic datasets. Image-to-image translation has recently received significant attention due to advances in deep learning. Most works focus on learning either a one-to-one mapping in an unsupervised way or a many-to-many mapping in a supervised way. However, a more practical setting is many-to-many mapping in an unsupervised way, which is harder due to the lack of supervision and the complex inner- and cross-domain variations. To alleviate these issues, we propose the Exemplar Guided & Semantically Consistent Image-to-image Translation (EGSC-IT) network which conditions the translation process on an exemplar image in the target domain. We assume that an image comprises of a content component which is shared across domains, and a style component specific to each domain. Under the guidance of an exemplar from the target domain we apply Adaptive Instance Normalization to the shared content component, which allows us to transfer the style information of the target domain to the source domain. To avoid semantic inconsistencies during translation that naturally appear due to the large inner- and cross-domain variations, we introduce the concept of feature masks that provide coarse semantic guidance without requiring the use of any semantic labels. Experimental results on various datasets show that EGSC-IT does not only translate the source image to diverse instances in the target domain, but also preserves the semantic consistency during the process. Unsupervised image-to-image translation is an important and challenging problem in computer vision. Given an image in the source domain, the goal is to learn the conditional distribution of corresponding images in the target domain, without seeing any examples of corresponding image pairs. While this conditional distribution is inherently multimodal, existing approaches make an overly simplified assumption, modeling it as a deterministic one-to-one mapping. As a result, they fail to generate diverse outputs from a given source domain image. To address this limitation, we propose a Multimodal Unsupervised Image-to-image ( Translation (MUNIT) ) framework. We assume that the image representation can be decomposed into a content code that is domain-invariant, and a style code that captures domain-specific properties. To translate an image to another domain, we recombine its content code with a random style code sampled from the style space of the target domain. We analyze the proposed framework and establish several theoretical results. Extensive experiments with comparisons to state-of-the-art approaches further demonstrate the advantage of the proposed framework. Moreover, our framework allows users to control the style of translation outputs by providing an example style image. Code and pretrained models are available at https: github.com nvlabs MUNIT. Unsupervised image-to-image translation is an important and challenging problem in computer vision. Given an image in the source domain, the goal is to learn the conditional distribution of corresponding images in the target domain, without seeing any pairs of corresponding images. While this conditional distribution is inherently multimodal, existing approaches make an overly simplified assumption, modeling it as a deterministic one-to-one mapping. As a result, they fail to generate diverse outputs from a given source domain image. To address this limitation, we propose a Multimodal Unsupervised Image-to-image Translation (MUNIT) framework. We assume that the image representation can be decomposed into a content code that is domain-invariant, and a style code that captures domain-specific properties. To translate an image to another domain, we recombine its content code with a random style code sampled from the style space of the target domain. We analyze the proposed framework and establish several theoretical results. Extensive experiments with comparisons to the state-of-the-art approaches further demonstrates the advantage of the proposed framework. Moreover, our framework allows users to control the style of translation outputs by providing an example style image. Code and pretrained models are available at this https URL Recent studies on unsupervised image-to-image translation have made remarkable progress by training a pair of generative adversarial networks with a cycle-consistent loss. However, such unsupervised methods may generate inferior results when the image resolution is high or the two image domains are of significant appearance differences, such as the translations between semantic layouts and natural images in the Cityscapes dataset. In this paper, we propose novel Stacked Cycle-Consistent Adversarial Networks (SCANs) by decomposing a single translation into multi-stage transformations, which not only boost the image translation quality but also enable higher resolution image-to-image translation in a coarse-to-fine fashion. Moreover, to properly exploit the information from the previous stage, an adaptive fusion block is devised to learn a dynamic integration of the current stage’s output and the previous stage’s output. Experiments on multiple datasets demonstrate that our proposed approach can improve the translation quality compared with previous single-stage unsupervised methods. Image-to-image translation aims to learn the mapping between two visual domains. There are two main challenges for many applications: 1) the lack of aligned training pairs and 2) multiple possible outputs from a single input image. In this work, we present an approach based on disentangled representation for producing diverse outputs without paired training images. To achieve diversity, we propose to embed images onto two spaces: a domain-invariant content space capturing shared information across domains and a domain-specific attribute space. Our model takes the encoded content features extracted from a given input and the attribute vectors sampled from the attribute space to produce diverse outputs at test time. To handle unpaired training data, we introduce a novel cross-cycle consistency loss based on disentangled representations. Qualitative results show that our model can generate diverse and realistic images on a wide range of tasks without paired training data. For quantitative comparisons, we measure realism with user study and diversity with a perceptual distance metric. We apply the proposed model to domain adaptation and show competitive performance when compared to the state-of-the-art on the MNIST-M and the LineMod datasets. Image-to-image translation is a class of vision and graphics problems where the goal is to learn the mapping between an input image and an output image using a training set of aligned image pairs. However, for many tasks, paired training data will not be available. We present an approach for learning to translate an image from a source domain X to a target domain Y in the absence of paired examples. Our goal is to learn a mapping G : X → Y such that the distribution of images from G(X) is indistinguishable from the distribution Y using an adversarial loss. Because this mapping is highly under-constrained, we couple it with an inverse mapping F : Y → X and introduce a cycle consistency loss to push F(G(X)) ≈ X (and vice versa). Qualitative results are presented on several tasks where paired training data does not exist, including collection style transfer, object transfiguration, season transfer, photo enhancement, etc. Quantitative comparisons against several prior methods demonstrate the superiority of our approach. Convolutional networks (ConvNets) have achieved great successes in various challenging vision tasks. However, the performance of ConvNets would degrade when encountering the domain shift. The domain adaptation is more significant while challenging in the field of biomedical image analysis, where cross-modality data have largely different distributions. Given that annotating the medical data is especially expensive, the supervised transfer learning approaches are not quite optimal. In this paper, we propose an unsupervised domain adaptation framework with adversarial learning for cross-modality biomedical image segmentations. Specifically, our model is based on a dilated fully convolutional network for pixel-wise prediction. Moreover, we build a plug-and-play domain adaptation module (DAM) to map the target input to features which are aligned with source domain feature space. A domain critic module (DCM) is set up for discriminating the feature space of both domains. We optimize the DAM and DCM via an adversarial loss without using any target domain label. Our proposed method is validated by adapting a ConvNet trained with MRI images to unpaired CT data for cardiac structures segmentations, and achieved very promising results. Cross-domain mapping has been a very active topic in recent years. Given one image, its main purpose is to translate it to the desired target domain, or multiple domains in the case of multiple labels. This problem is highly challenging due to three main reasons: (i) unpaired datasets, (ii) multiple attributes, and (iii) the multimodality associated with the translation. Most of the existing state-of-the-art has focused only on two reasons, i.e. producing disentangled representations from unpaired datasets in a one-to-one domain translation or producing multiple unimodal attributes from unpaired datasets. In this work, we propose a joint framework of diversity and multi-mapping image-to-image translations, using a single generator to conditionally produce countless and unique fake images that hold the underlying characteristics of the source image. Extensive experiments over different datasets demonstrate the effectiveness of our proposed approach with comparisons to the state-of-the-art in both multi-label and multimodal problems. Additionally, our method is able to generalize under different scenarios: continuous style interpolation, continuous label interpolation, and multi-label mapping. Unsupervised image-to-image translation aims at learning a joint distribution of images in different domains by using images from the marginal distributions in individual domains. Since there exists an infinite set of joint distributions that can arrive the given marginal distributions, one could infer nothing about the joint distribution from the marginal distributions without additional assumptions. To address the problem, we make a shared-latent space assumption and propose an unsupervised image-to-image translation framework based on Coupled GANs. We compare the proposed framework with competing approaches and present high quality image translation results on various challenging unsupervised image translation tasks, including street scene image translation, animal image translation, and face image translation. We also apply the proposed framework to domain adaptation and achieve state-of-the-art performance on benchmark datasets. Code and additional results are available in this https URL .